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https://www.readbyqxmd.com/read/28802596/effects-of-differential-phase-remote-ischemic-preconditioning-intervention-in-laparoscopic-partial-nephrectomy-a-single-blinded-randomized-controlled-trial-in-a-parallel-group-design
#1
Yuan-Yuan Hou, Yun Li, Shu-Fang He, Jie Song, De-Xin Yu, Gordon T C Wong, Ye Zhang
STUDY OBJECTIVE: There are two windows of protection for remote ischemic preconditioning (RIPC), an early (ERIPC) and a late-phase (LRIPC). While ERIPC has been well studied, works on LRIPC are relatively scarce, especially for the kidneys. We aimed to compare the effects of early-phase versus late-phase RIPC in patients with laparoscopic partial nephrectomy (LPN). DESIGN: A randomized controlled study SETTING: The Second Affiliated Hospital of Anhui Medical University, 1 May 2012 to 30 October 2013 PATIENTS: Sixty-five ASA 1 to 2 patients scheduled for LPN were located randomly to ERIPC group, LRIPC group and CON group (control)...
September 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28797586/obesity-as-defined-by-waist-circumference-but-not-body-mass-index-is-associated-with-higher-renal-mass-complexity
#2
Laura A Bertrand, Lewis J Thomas, Peng Li, Claire M Buchta, Shannon K Boi, Rachael M Orlandella, James A Brown, Kenneth G Nepple, Lyse A Norian
OBJECTIVES: Obesity, typically defined as a body mass index (BMI)≥30kg/m(2), is an established risk factor for renal cell carcinoma (RCC) but is paradoxically linked to less advanced disease at diagnosis and improved outcomes. However, BMI has inherent flaws, and alternate obesity-defining metrics that emphasize abdominal fat are available. We investigated 3 obesity-defining metrics, to better examine the associations of abdominal fat vs. generalized obesity with renal tumor stage, grade, or R...
August 7, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28764630/optimising-assessment-of-kidney-function-when-managing-localised-renal-masses
#3
REVIEW
Robert J Ellis, Andre Joshi, Keng L Ng, Ross S Francis, Glenda C Gobe, Simon T Wood
Increased early and incidental detection, improved surgical techniques and technological advancement mean that the management of renal mass lesions is constantly evolving. The treatment of choice for renal mass lesions has historically been radical nephrectomy. Partial nephrectomy is now recommended for localised renal masses, owing to favourable renal functional outcomes. Ablative renal surgery confers a significant risk of chronic kidney disease. There are few studies assessing long term outcomes of nephrectomy on renal outcomes, and virtually no studies assessing long term outcomes for less invasive therapies such as ablation...
August 7, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28749068/trifecta-outcomes-of-robot-assisted-partial-nephrectomy-in-solitary-kidney-a-vattikuti-collective-quality-initiative-vcqi-database-analysis
#4
Sohrab Arora, Ronney Abaza, James M Adshead, Rajesh K Ahlawat, Benjamin J Challacombe, Prokar Dasgupta, Giorgio Gandaglia, Daniel A Moon, T B Yuvaraja, Umberto Capitanio, Alessandro Larcher, Francesco Porpiglia, James R Porter, Alexander Mottrie, Mahendra Bhandari, Craig Rogers
OBJECTIVES: To analyze the outcomes of robot-assisted partial nephrectomy (RAPN) in patients with a solitary kidney in a large multi-institutional database. PATIENTS AND METHODS: A total of 2755 patients in the Vattikuti Collective Quality Initiative database underwent RAPN by 22 surgeons at 14 centers in nine 9 countries. Out of these patients, 74 underwent RAPN in solitary kidney between 2007 and 2016. A retrospective analysis of the functional and oncological outcomes was performed...
July 27, 2017: BJU International
https://www.readbyqxmd.com/read/28741414/the-decline-of-laparoendoscopic-single-site-surgery-a-survey-of-the-endourological-society-to-identify-shortcomings-and-guidance-for-future-directions
#5
Igor Sorokin, Noah E Canvasser, Brian Irwin, Riccardo Autorino, Evangelos N Liatsikos, Jeffrey A Cadeddu, Abhay Rane
INTRODUCTION: To analyze the most recent temporal trends in the adoption of urologic laparoendoscopic single-site (LESS), to identify the perceived limitations associated with its decline, and to determine factors that might revive the role of LESS in the field of minimally invasive urological surgery. METHODS: A 15 question survey was created and sent to members of the Endourological Society in September 2016. Only members who performed LESS procedures in practice were asked to respond...
July 25, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28741377/renal-cell-carcinoma-alternative-nephron-sparing-treatment-options-for-small-renal-masses-a-systematic-review
#6
Fieke M Prins, Linda G W Kerkmeijer, Anne A Pronk, Evert-Jan P A Vonken, Richard P Meijer, Axel Bex, Maurits M Barendrecht
<i>Background</i> The standard treatment of T1 renal cell carcinoma is (partial-) nephrectomy. For patients where surgery is not the treatment of choice, for example in the elderly, in case of severe comorbidity, inoperability or refusal of surgery, alternative treatment options are available. These treatment options include active surveillance, radiofrequency ablation, cryoablation, microwave ablation or stereotactic body radiotherapy. In the present overview, the efficacy, safety and outcome of these different options are summarized, particularly focusing on recent developments...
July 25, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28731925/thoracic-paravertebral-block-for-postoperative-pain-management-after-renal-surgery-a-randomised-controlled-trial
#7
Maja Copik, Szymon Bialka, Andrzej Daszkiewicz, Hanna Misiolek
BACKGROUND: Thoracic paravertebral block (ThPVB) combined with general anaesthesia is used in thoracic and general surgery. It provides effective analgesia, reduces surgical stress response and the incidence of chronic postoperative pain. OBJECTIVE: To assess the efficacy of ThPVB in reducing opioid requirements and decreasing the intensity of pain after renal surgery. DESIGN: A randomised, open label study. SETTING: A single university hospital...
September 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28727381/nephrometry-scores-and-perioperative-outcomes-following-robotic-partial-nephrectomy
#8
Renato B Corradi, Emily A Vertosick, Daniel P Nguyen, Antoni Vilaseca, Daniel D Sjoberg, Nicole Benfante, Lucas N Nogueira, Massimiliano Spaliviero, Karim A Touijer, Paul Russo, Jonathan A Coleman
OBJECTIVES: Based on imaging features, nephrometry scoring systems have been conceived to create a standardized and reproducible way to characterize renal tumor anatomy. However, less is known about which of these individual measures are important with regard to clinically relevant perioperative outcomes such as ischemia time (IT), estimated blood loss (EBL), length of hospital stay (LOS), and change in estimated glomerular filtration rate (eGFR) after robotic partial nephrectomy (PN)...
July 20, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28719609/renal-function-following-xenon-anesthesia-for-partial-nephrectomy-an-explorative-analysis-of-a-randomized-controlled-study
#9
Ana Stevanovic, Patrick Schaefer, Mark Coburn, Rolf Rossaint, Christian Stoppe, Peter Boor, David Pfister, Axel Heidenreich, Hildegard Christ, Martin Hellmich, Astrid V Fahlenkamp
BACKGROUND: Perioperative preservation of renal function has a significant impact on morbidity and mortality in kidney surgery. Nephroprotective effects of the anesthetic xenon on ischemia-reperfusion injury were found in several experimental studies. OBJECTIVE: We aimed to explore whether xenon anesthesia can reduce renal damage in humans undergoing partial nephrectomy and to gather pilot data of possible nephroprotection in these patients. DESIGN: A prospective randomized, single-blinded, controlled study...
2017: PloS One
https://www.readbyqxmd.com/read/28716561/influence-of-renal-biopsy-results-on-the-management-of-small-kidney-cancers-in-older-patients-results-from-a-population-based-cohort
#10
Marc A Bjurlin, Elena B Elkin, Coral L Atoria, Paul Russo, Samir S Taneja, William C Huang
BACKGROUND AND OBJECTIVE: Small kidney cancers are a heterogeneous group with varying malignant potential. Pathologic information obtained from a renal biopsy may guide decision-making for small kidney cancers. We sought to assess the effect of pathologic information from renal biopsy on the nonsurgical management of small kidney cancers in a population-based cohort of patients over 65 years of age. METHODS: In the Surveillance, Epidemiology and End Results-Medicare dataset, we identified patients ≥66 years diagnosed with a kidney cancer<4cm between 2002 and 2011...
July 14, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28704481/renal-auto-transplantation-promotes-cortical-microvascular-network-remodeling-in-a-preclinical-porcine-model
#11
Souleymane Maïga, Geraldine Allain, Thierry Hauet, Jerome Roumy, Edouard Baulier, Michel Scepi, Manuel Dierick, Luc Van Hoorebeke, Patrick Hannaert, Franck Guy, Frederic Favreau
The vascular network is a major target of ischemia-reperfusion, but has been poorly investigated in renal transplantation. The aim of this study was to characterize the remodeling of the renal vascular network that follows ischemia-reperfusion along with the most highly affected cortex section in a preclinical renal transplantation model. There were two experimental groups. The first was a grafted kidney group consisting of large white pigs for which the left kidney was harvested, cold flushed, preserved for 24 h in the University of Wisconsin's preservation solution, and then auto-transplanted (n = 5); the right kidney was removed to mimic the situation of human kidney transplantation...
2017: PloS One
https://www.readbyqxmd.com/read/28701891/comprehensive-analysis-of-factors-affecting-post-partial-nephrectomy-renal-global-function
#12
Takehiro Sejima, Tetsuya Yumioka, Noriya Yamaguchi, Hideto Iwamoto, Toshihiko Masago, Shuichi Morizane, Masashi Honda, Atsushi Takenaka
BACKGROUND: To explore new factors that are predictive of post-partial nephrectomy (PN) renal global function, we analyzed various clinico-pathological factors with a special focus on renal volume measured via three-dimensional imaging technology and histopathological parameters in non-neoplastic parenchyma. METHODS: Estimated glomerular filtration rate (eGFR) and computed tomography (CT) scan were examined pre- and 6 months. post-operatively in 52 patients treated by PN...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28664237/surgical-and-minimally-invasive-therapies-for-the-management-of-the-small-renal-mass
#13
REVIEW
John Withington, Joana B Neves, Ravi Barod
PURPOSE OF REVIEW: This article aims to summarise recent developments in surgical and minimally invasive therapies in the management of small renal masses (SRMs). RECENT FINDINGS: The incidence of the small renal mass is increasing. Standard management of the SRM is partial nephrectomy. More recently, use of ablative techniques to manage the SRM has been increasing and an exciting array of technical advances is currently being made in the field. Nephron-sparing surgery looks set to become more financially viable with the advent of newer robotic platforms and, potentially, even less invasive with the evaluation of single-port access...
August 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28656359/comparison-of-retroperitoneal-and-transperitoneal-robotic-partial-nephrectomy-for-pentafecta-perioperative-and-renal-functional-outcomes
#14
Sean P Stroup, Zachary A Hamilton, Michael T Marshall, Hak J Lee, Sean W Berquist, Abd-Elrahman S Hassan, Alp T Beksac, Charles A Field, Aaron Bloch, Fang Wan, Michelle L McDonald, Nishant D Patel, James O L'Esperance, Ithaar H Derweesh
BACKGROUND: We compared quality outcomes between transperitoneal (TRPN) and retroperitoneal robotic partial nephrectomy (RRPN). METHODS: Two-center retrospective analysis of TRPN and RRPN from 10/2009 to 10/2015. Perioperative/renal function outcomes were analyzed. Primary endpoint was Pentafecta, a composite measure of quality [negative margin, no 30-day complication, ischemia time ≤25 min, return of glomerular filtration rate (eGFR) to >90% from baseline at last follow-up, and no chronic kidney disease upstaging]...
June 27, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28652124/ureterocalicostomy-for-reconstruction-of-complicated-ureteropelvic-junction-obstruction-in-adults-long-term-outcome-factors-predicting-its-failure-in-contemporary-cohort
#15
Devarshi Srivastava, Sanjoy K Sureka, Priyank Yadav, Ankur Bansal, Shashikant Gupta, Rakesh Kapoor, M S Ansari, Aneesh Srivastava
INTRODUCTION: Ureterocalicostomy (UC) is a well-established treatment option for patients with recurrent ureteropelvic junction obstruction (UPJO) with postoperative fibrosis and a relatively inaccessible renal pelvis. This study aimed to evaluate the long-term outcome of UC and factors predicting its failure. MATERIALS AND METHODS: We retrospectively analysed data of 72 patients who underwent open or laparoscopic UC from 2000 to 2014. Variables that may affect the outcomes of UC were assessed with regard to primary pathology, age, serum creatinine, preoperative renal size (<15 cm and > 15 cm), renal cortical thickness (<5mm and >5 mm), grade of hydronephrosis and preoperative renal function (GFR < or >20 ml/min)...
June 23, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28624829/preoperative-c-reactive-protein-values-as-a-potential-component-in-outcome-prediction-models-of-metastasized-renal-cell-carcinoma-patients-receiving-cytoreductive-nephrectomy
#16
Charis Kalogirou, Philipp Mulfinger, Ioannis Sokolakis, Markus Krebs, Hubert Kübler, Hubertus Riedmiller, Daniel Vergho
PURPOSE: To validate preoperative C-reactive protein (CRP) levels as a prognostic marker for survival in a metastasized renal cell carcinoma (mRCC) patient cohort receiving cytoreductive nephrectomy (CN). PATIENTS AND METHODS: By chart review, 146 mRCC patients receiving CN at our tertiary referral centre from 1997 to 2015 were identified retrospectively. All relevant clinicopathological features including laboratory parameters were collected and correlated to overall survival, progression-free survival and cancer-specific survival (CSS)...
June 17, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28623071/overall-survival-in-swedish-patients-with-renal-cell-carcinoma-treated-in-the-period-2002-to-2012-update-of-the-rencomp-study-with-subgroup-analysis-of-the-synchronous-metastatic-and-elderly-populations
#17
Magnus Lindskog, Thomas Wahlgren, Rickard Sandin, Jan Kowalski, Maria Jakobsson, Sven Lundstam, Börje Ljungberg, Ulrika Harmenberg
BACKGROUND: This retrospective study investigated overall survival (OS) and factors influencing OS in Swedish patients with metastatic renal cell carcinoma (mRCC) during the pre- (2002-2005), early (2006-2008), and late (2009-2012) targeted therapy (TT) era. METHODS: Three national Swedish registries identified patients with mRCC. Median OS was estimated using the Kaplan-Meier method. Multivariate analysis was performed using Cox proportional hazards regression...
June 13, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28604288/laparoendoscopic-single-site-nephrectomy-for-hemodialysis-patients-with-dialysis-related-renal-tumors
#18
Kohei Takei, Mutsushi Yamasaki, Satoki Abe, Naoyuki Yamanaka, Shinya Sejiyama, Takahiro Narimatsu, Shinro Hata, Tadamasa Shibuya, Kenichi Hirai, Tadasuke Ando, Toshitaka Shin, Kenichi Mori, Yasuhiro Sumino, Takeo Nomura, Fuminori Sato, Toshiro Terachi, Hiromitsu Mimata
PURPOSE: The purpose of this study is to assess the efficacy of laparoendoscopic single-site (LESS) nephrectomy in hemodialysis patients, we compared outcomes between LESS nephrectomy and conventional laparoendoscopic nephrectomy in hemodialysis patients with dialysis-related renal tumors. MATERIAL AND METHODS: A total of 16 hemodialysis patients who underwent LESS nephrectomy (LESS-N; n = 8) or conventional laparoendoscopic nephrectomy (C-N; n = 8) between November 2003 and July 2012 were retrospectively evaluated...
June 12, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28588626/clinical-and-paraclinical-evaluation-of-partial-nephrectomy-using-laparoscopy-and-open-surgery-in-dogs-new-suturing-technique
#19
E Shariati, J Bakhtiari, A Khalaj, M Molazem, E Shariati, A Niasari-Naslaji
Partial nephrectomy, using open surgery or laparoscopy, is a standard surgical approach to treat renal disorders. The objective of this study was to compare and evaluate the feasibility and safety of laparoscopic partial nephrectomy using figure eight ligation technique. Mixed-breed dogs were randomly dedicated for partial nephrectomy using laparoscopy (n=6) and open surgery (n=6). During 30 days after operation, clinical, hematological and ultrasonographic findings, intra- and post-operative complications, operation and ischemia times, urine analysis and incision length were recorded...
2017: Iranian journal of veterinary research
https://www.readbyqxmd.com/read/28583563/impact-of-the-ratio-of-visceral-to-subcutaneous-adipose-tissue-in-donor-nephrectomy-patients
#20
H H Lee, S K Kang, Y E Yoon, K H Huh, M S Kim, S I Kim, Y S Kim, W K Han
OBJECTIVE: It was reported that a metabolic syndrome affected the remaining renal function after living donor nephrectomy. However, the measurement of waist circumference is unclear because it cannot distinguish between visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT). We investigate the clinical correlation between body adipose tissue and renal function recovery after living donor nephrectomy. METHODS: From July 2013 to February 2015, 75 living kidney donors were enrolled...
June 2017: Transplantation Proceedings
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