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https://www.readbyqxmd.com/read/28103834/depression-alcohol-use-and-intimate-partner-violence-among-outpatients-in-rural-uganda-vulnerabilities-for-hiv-stis-and-high-risk-sexual-behavior
#1
Susan M Kiene, Haruna Lule, Katelyn M Sileo, Kazi Priyanka Silmi, Rhoda K Wanyenze
BACKGROUND: Intimate partner violence (IPV), alcohol use, and depression are key vulnerabilities for HIV in Uganda, and taken together may have a synergistic effect on risk. Our objective was to investigate the associations between depression, IPV, and alcohol use and HIV-risk indicators among a sample of outpatients in rural Uganda, and the effect of co-occurrence of these factors on HIV-risk indicators. METHODS: In a structured interview we collected data on high-risk sexual behavior, depression symptoms, emotional and physical IPV, and alcohol use, as well as a blood sample for HIV and syphilis tests and a urine sample for chlamydia and gonorrhea tests from 325 male and female outpatients receiving provider-initiated HIV testing and counseling (PITC) at a public hospital outpatient clinic in rural Uganda...
January 19, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28103295/prevalence-and-trends-of-hiv-syphilis-and-hcv-in-migrant-and-resident-men-who-have-sex-with-men-in-shandong-china-results-from-a-serial-cross-sectional-study
#2
Jun Hu, Xu Gu, Xiaorun Tao, Yaosheng Qian, Giridhara R Babu, Guoyong Wang, Meizhen Liao, Larry Han, Dianmin Kang, Weiming Tang
BACKGROUND: Migrant men who have sex with men (MSM) have a higher predisposition for HIV transmission. We aimed to determine and compare the prevalence and trends of HIV, Syphilis, and HCV between migrant and resident MSM in Shandong, China. METHODS: A serial cross-sectional study was conducted in eight cities in Shandong, China from 2010 to 2014. The surveys collected information on demographics, HIV-related knowledge, and HIV-related behaviors including the serologic status of HIV, syphilis, and HCV...
2017: PloS One
https://www.readbyqxmd.com/read/28100187/prevalence-of-hiv-and-syphilis-co-infection-and-associated-factors-among-non-commercial-men-who-have-sex-with-men-attending-a-sexually-transmitted-disease-clinic-in-shenzhen-china
#3
Wenjie Dai, Zhenzhou Luo, Ruiwei Xu, Guanglu Zhao, Dan Tu, Lin Yang, Feng Wang, Yumao Cai, Lina Lan, Fuchang Hong, Tubao Yang, Tiejian Feng
BACKGROUND: Although HIV and syphilis co-infection has been frequently observed in men who have sex with men (MSM), only few studies have focused on it. Different subgroups of MSM might exhibit heterogeneous HIV and syphilis risk profiles, indicating that interventions for HIV and HIV-related co-infections may vary with different subgroups of MSM. However, no previous study has investigated HIV and syphilis co-infection among non-commercial MSM (ncMSM) attending a sexually transmitted disease (STD) clinic...
January 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28100178/a-retinopathy-in-young-patient-with-co-inheritance-of-heterozygous-alpha%C3%A2-%C3%A2-thalassemia-and-sickle-trait-a-case-report
#4
Zohra Ouzzif, Aissam El Maataoui, Zeinab Traore, Asmae Biaz, Samira El Machtani, Abdellah Dami, Sanae Bouhsain, Nezha Messaoudi, Fatiha Benchrifa
BACKGROUND: The retinopathy is an uncommon complication in individuals with sickle cell trait except for the cases of sickle cell trait associated with systemic arterial hypertension, diabetes mellitus, syphilis, tuberculosis and sarcoidosis. CASE PRESENTATION: A retinopathy in a 16 year-old child with no history of consanguinity in the parents revealed a sickle S trait associated to heterozygous alpha thalassemia. His mother has Sickle cell anaemia (Hb SS) and his father is a carrier of heterozygous alpha-thalassemia status that it was unknown before...
January 18, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28096307/-he-would-by-no-means-risque-his-reputation-patient-and-doctor-shame-in-daniel-turner-s-de-morbis-cutaneis-1714-and-syphilis-1717
#5
Emily Cock
This article offers a historical corollary to the examination of shame in medical practice by considering the negotiation of shame in the treatment of a stigmatised disease at a time in which surgeons themselves occupied a highly ambivalent social position. It will focus on case studies provided by Daniel Turner (1667-1741), prominent surgeon and later member of the College of Physicians, in his textbooks De Morbis Cutaneis. A Treatise of Diseases Incident to the Skin (1714) and Syphilis. A Practical Dissertation on the Venereal Disease (1717)...
January 17, 2017: Medical Humanities
https://www.readbyqxmd.com/read/28095879/treatment-seeking-behaviour-and-barriers-to-service-access-for-sexually-transmitted-diseases-among-men-who-have-sex-with-men-in-china-a-multicentre-cross-sectional-survey
#6
Jun-Jie Xu, Yan-Qiu Yu, Qing-Hai Hu, Hong-Jing Yan, Zhe Wang, Lin Lu, Ming-Hua Zhuang, Xi Chen, Ji-Hua Fu, Wei-Ming Tang, Wen-Qing Geng, Yong-Jun Jiang, Hong Shang
BACKGROUND: Delayed or inappropriate treatment for sexually transmitted diseases (STDs) increases the risk of HIV acquisition and may cause other harmful outcomes. However, studies on STD treatment-seeking behaviour and correlated factors in men who have sex with men (MSM) are scarce. This information is crucial for the promotion of STD treatment-seeking behaviour and reduction of HIV transmission among Chinese MSM. METHODS: During 2012-2013, a multicentre cross-sectional study was conducted in 7 Chinese cities...
January 18, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28094553/burden-of-hiv-syphilis-and-hepatitis-b-and-c-among-inmates-in-a-prison-state-system-in-mexico
#7
Pablo F Belaunzaran-Zamudio, Juan Luis Mosqueda-Gómez, Alejandro Macías-Hernández, Sonia Rodríguez-Ramírez, Juan Sierra-Madero, Chris Beyrer
We studied the prevalence of HIV, syphilis, HBV and HCV infection and associated risk behaviors in the prison state system of Guanajuato, Mexico between September 2011 and February 2012. Blood samples were drawn from adult inmates in all State prisons agreeing to participate in this cross-sectional study. Data on risk behaviors was collected using self-administered questionnaires. Prevalence of HIV, syphilis, HBV and HCV infection was 0.6% (95%CI=0.2-1.1), 0.7% (95%CI=0.4-1.0), 0.4 (95%CI=0.04-0.74) and 4.8 (95%CI=3...
January 17, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28094165/psoriasiform-dermatitides-a-brief-review
#8
Mark R Wick
Psoriasis vulgaris (PV)-the prototypical "psoriasiform" dermatitis-may assume a spectrum of histologic appearances, depending on whether it has been treated or not. Because of that relative lack of morphological uniformity, other skin disorders that feature epidermal acanthosis, with or without associated inflammation, may be confused diagnostically with PV. This brief review considers the clinicopathologic attributes of PV and its imitators, including chronic spongiotic dermatitides, lichen simplex chronicus, prurigo nodularis, pityriasis rubra pilaris, psoriasiform secondary syphilis, and Reiter syndrome...
December 14, 2016: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/28093460/a-double-edged-sword-does-highly-active-antiretroviral-therapy-contribute-to-syphilis-incidence-by-impairing-immunity-to-treponema-pallidum
#9
REVIEW
Michael L Rekart, Wilfred Ndifon, Robert C Brunham, Jonathan Dushoff, Sang Woo Park, Sanjana Rawat, Caroline E Cameron
BACKGROUND AND HYPOTHESIS: Recently, the world has experienced a rapidly escalating outbreak of infectious syphilis primarily affecting men who have sex with men (MSM); many are taking highly active antiretroviral therapy (HAART) for HIV-1 infection. The prevailing hypothesis is that HAART availability and effectiveness have led to the perception among both individuals who are HIV-1 infected and those who are uninfected that HIV-1 transmission has become much less likely, and the effects of HIV-1 infection less deadly...
January 16, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28093459/syphilis-and-hiv-is-haart-at-the-heart-of-this-epidemic
#10
EDITORIAL
Susan Tuddenham, Maunank Shah, Khalil G Ghanem
No abstract text is available yet for this article.
January 16, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28081374/cytokine-profiles-in-aqueous-humor-and-plasma-of-hiv-infected-individuals-with-ocular-syphilis-or-cytomegalovirus-retinitis
#11
Matilde Ruiz-Cruz, Santiago Ávila-Rios, Christopher E Ormsby, Yuria Ablanedo-Terrazas, Claudia Alvarado-de la Barrera, Leticia Kuri-Cervantes, Gustavo Reyes-Terán
PURPOSE: To characterize the immunologic profile in aqueous humor (AqH) of HIV-infected individuals with cytomegalovirus retinitis (CMVr) or ocular syphilis and to assess if AqH and plasma represent independent cytokine compartments. METHODS: Concentrations of 27 cytokines in AqH and plasma of HIV-infected individuals with CMVr (n = 23) or ocular syphilis (n = 16) were measured by multiplex assay. Cytokine profiles of both groups were compared. RESULTS: Individuals with CMVr had higher plasma concentrations of interleukin (IL)-7, IL-8, IL-10, interferon (IFN)-γ, IFN-α2, G-CSF, IP-10 and IL-1α; as well as higher AqH concentrations of IL-1α, IP-10 and GM-CSF than those with ocular syphilis...
January 12, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28079920/serum-microrna-profiles-in-patients-with-syphilis
#12
Ping Lu, Chang Fang, Qing Cheng, Wu-Jian Ke, Tao Huang, Jun Zhang, He-Ping Zheng, Bin Yang
Syphilis is an acute and chronic inflammatory disorder caused by the non-cultivatable spirochete Treponema pallidum subsp. pallidum (T. pallidum).(1,2) T. pallidum does not produce any known toxic proteins; therefore, most of the symptoms and tissue damage related to syphilis are caused by activation of the host's inflammatory and immune responses,(3) thus suggesting that host genetics play an important role in regulating the progression of syphilis infection. MiRNAs are a class of 19- to 24-nt noncoding RNAs that influence many biological systems, including development, cellular differentiation, proliferation, apoptosis, metabolism, and the immune response;(4-6) they also play crucial roles during microbial infection...
January 12, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28079818/factors-associated-with-syphilis-incidence-in-the-hiv-infected-in-the-era-of-highly-active-antiretrovirals
#13
Mohaned Shilaih, Alex Marzel, Dominique L Braun, Alexandra U Scherrer, Helen Kovari, Jim Young, Alexandra Calmy, Katharine Darling, Manuel Battegay, Matthias Hoffmann, Enos Bernasconi, Maria C Thurnheer, Huldrych F Günthard, Roger D Kouyos
After several years of steady decline, syphilis is reemerging globally as a public health hazard, especially among people living with human immunodeficiency virus (HIV). Syphilis resurgence is observed mainly in men who have sex with men (MSM), yet other transmission groups are affected too. In this manuscript, we study the factors associated with syphilis incidence in the Swiss HIV cohort study in the era of highly effective antiretrovirals. Using parametric interval censored models with fixed and time-varying covariates, we studied the immunological, behavioral, and treatment-related elements associated with syphilis incidence in 3 transmission groups: MSM, heterosexuals, and intravenous drug users...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28077740/the-jarisch-herxheimer-reaction-after-antibiotic-treatment-of-spirochetal-infections-a-review-of-recent-cases-and-our-understanding-of-pathogenesis
#14
REVIEW
Thomas Butler
Within 24 hours after antibiotic treatment of the spirochetal infections syphilis, Lyme disease, leptospirosis, and relapsing fever (RF), patients experience shaking chills, a rise in temperature, and intensification of skin rashes known as the Jarisch-Herxheimer reaction (JHR) with symptoms resolving a few hours later. Case reports indicate that the JHR can also include uterine contractions in pregnancy, worsening liver and renal function, acute respiratory distress syndrome, myocardial injury, hypotension, meningitis, alterations in consciousness, seizures, and strokes...
January 11, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28076583/-social-factors-associated-with-use-of-prenatal-care-in-ecuador
#15
Amaya Sánchez-Gómez, William Cevallos, Mario J Grijalva, Luis C Silva-Ayçaguer, Susana Tamayo, Jerry O Jacobson, Jaime A Costales, Rodrigo Jiménez-Garcia, Valentín Hernández-Barrera, Suzanne Serruya, Celia Riera
Objectives: Prenatal care is a pillar of public health, enabling access to interventions including prevention of mother-to-child transmission of HIV and congenital syphilis. This paper describes social factors related to use of prenatal care in Ecuador. Methods: In 2011 and 2012, participant clinical history and interview information was analyzed from a national probability sample of 5 998 women presenting for delivery or miscarriage services in 15 healthcare facilities in Ecuador, to estimate prevalence of HIV, syphilis, and Chagas disease, and prenatal care coverage...
November 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28070492/kissing-chancre-of-primary-syphilis
#16
Xiao Ke Liu, Zhong Shuai Wang, Jun Li
No abstract text is available yet for this article.
2017: IDCases
https://www.readbyqxmd.com/read/28058468/-nonviral-sexually-transmitted-infections-epidemiology-clinical-manifestations-diagnostic-workup-therapy-part%C3%A2-3-treponemes-gardnerella-and-trichomonads
#17
REVIEW
P Nenoff, A Manos, I Ehrhard, C Krüger, U Paasch, P Helmbold, W Handrick
In Germany, the reported syphilis prevalence has increased continuously since 2010, with a total of 6834 syphilis cases being reported in 2015. The largest increase of reported syphilis occurred in men who have sex with men (MSM). The antibiotic agent of choice for treatment of syphilis is still penicillin. There are no penicillin-resistant Treponema pallidum strains. Alternatives are ceftriaxone and doxycycline. In Germany, azithromycin is not approved for treatment of syphilis; however, therapy failures are increasingly reported...
January 5, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28057143/-infection-status-of-hiv-in-men-who-have-sex-with-men-in-nanjing-2011-2015
#18
Y Y Xu, Z P Zhu, S S Wu, Z Q Pu, L Liu, L Guo, M Zhang
Objective: To understand the current status of HIV infection in men who have sex with men (MSM) in Nanjing, explore the associated factors with HIV infection, and provide information for the intervention in MSM. Methods: Data collected in the consecutive sentinel surveillances among MSM during 2011-2015 includes MSM's social-demographic information, sexual behavior histories, access to HIV prevention services and HIV testing in the past year. The infection trend was analyzed with χ(2) test and the factors associated with HIV infection were identified through multivariate logistic regression analysis...
November 10, 2016: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28056870/anti-n-methyl-d-aspartate-receptor-nmdar-antibody-encephalitis-presents-in-atypical-types-and-coexists-with-neuromyelitis-optica-spectrum-disorder-or-neurosyphilis
#19
Kaiyu Qin, Wenqing Wu, Yuming Huang, Dongmei Xu, Lei Zhang, Bowen Zheng, Meijuan Jiang, Cheng Kou, Junhua Gao, Wurong Li, Jinglin Zhang, Sumei Wang, Yanfei Luan, Chaoling Yan, Dan Xu, Xinmei Zheng
BACKGROUND: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a clinically heterogeneous disorder characterized by epileptic seizures, psychosis, dyskinesia, consciousness impairments, and autonomic instability. Symptoms are always various. Sometimes it presents in milder or incomplete forms. We report 4 cases of anti-NMDAR encephalitis with incomplete forms, 3 cases of which were accompanied by neuromyelitis optica spectrum disorder or neurosyphilis respectively. CASE PRESENTATION: A 33-year-old man presented with dysarthria, movement disorder and occasional seizures...
January 5, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28052976/reciprocal-physical-intimate-partner-violence-is-associated-with-prevalent-sti-hiv-among-male-tanzanian-migrant-workers-a-cross-sectional-study
#20
Alison H Norris, Michele R Decker, Yiska L Weisband, Michelle J Hindin
OBJECTIVES: Physical intimate partner violence (IPV) and STIs, including HIV, are highly prevalent in east Africa. While we have some evidence about women's experience with physical IPV, little is known about men's experience with physical IPV, particularly in sub-Saharan Africa. Our objective was to examine, in Tanzanian male migrant plantation residents, the prevalence of, and associations among, experience and enactment of physical IPV and prevalent STI/HIV. METHODS: Data from a cross-sectional survey of male plantation residents (n=158) in northern Tanzania were analysed to estimate prevalence of physical IPV experience and enactment...
January 4, 2017: Sexually Transmitted Infections
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