Read by QxMD icon Read


Mohamad Reza Sedaghat, Hadi Ostadi-Moghadam, Mahmoud Jabbarvand, Farshad Askarizadeh, Hamed Momeni-Moghaddam, Foroozan Narooie-Noori
Purpose: To evaluate and compare corneal hysteresis (CH) and corneal resistance factor (CRF) in pellucid marginal degeneration (PMD), keratoconus (KCN), and normal eyes using the Ocular Response Analyzer (ORA). Methods: In this retrospective study, corneal biomechanical parameters were measured in patients with PMD ( n  = 102) and KCN ( n  = 202) and normal subjects ( n  = 208) using the ORA. Data, including full patient history as well as the results of refraction, slit-lamp biomicroscopy, Pentacam HR (Oculus), and ORA (Reichert; Buffalo, New York, USA), were collected from medical records...
March 2018: Journal of Current Ophthalmology
Lyndsay Brown, William Foulsham, Savva Pronin, Andrew J Tatham
PURPOSE: To examine the effect of corneal biomechanical properties on intraocular pressure (IOP) measurements obtained using a rebound self-tonometer (Icare HOME) compared to Goldmann applanation tonometry (GAT). METHODS: An observational study of 100 patients with glaucoma or ocular hypertension. All had a comprehensive ophthalmic examination and standard automated perimetry. IOP was assessed by GAT, Icare HOME and Ocular Response Analyzer (ORA), which was also used to assess corneal hysteresis (CH) and corneal resistance factor (CRF)...
March 19, 2018: Journal of Glaucoma
Sven Oras, Sergei Vlassov, Marta Berholts, Rünno Lõhmus, Karine Mougin
Adhesion forces between functionalized gold colloidal nanoparticles (Au NPs) and scanning probe microscope silicon tips were experimentally investigated by atomic force microscopy (AFM) equipped with PeakForce QNM (Quantitative Nanoscale Mechanics) module. Au NPs were synthesized by a seed-mediated process and then functionalized with thiols containing different functional groups: amino, hydroxy, methoxy, carboxy, methyl, and thiol. Adhesion measurements showed strong differences between NPs and silicon tip depending on the nature of the tail functional group...
2018: Beilstein Journal of Nanotechnology
Nicole Zimmermann, Svea Brandt, Jeanette Brünner, Carl Erb
INTRODUCTION: Our study compares the biomechanical properties of the cornea in patients with long-term pre-existing (for at least 10 years) systemic sclerosis (SSc) with those of healthy suspects. MATERIAL/METHODS: The examination was performed in 14 systemic SSc patients and 38 healthy volunteers. Non-invasive assessment of corneal biomechanical parameters, including central corneal thickness (CCT), corneal hysteresis (CH) and corneal resistance factor (CRF), was performed in one randomised study eye in accordance with a standardised protocol...
March 7, 2018: Klinische Monatsblätter Für Augenheilkunde
Saskia D M van Schaik, Ora Oudgenoeg-Paz, Osnat Atun-Einy
The present study explored cultural differences in parental beliefs about motor development across 2 Western cultures: Israel and the Netherlands. Can 2 cultural models be distinguished regarding infant motor development in Israel and the Netherlands or are parental beliefs about motor development similar across these cultures? Using a questionnaire containing closed and open questions, beliefs of 206 Israeli and 198 Dutch parents of first-born children between 2 and 7 months old were analyzed. Based on both quantitative and qualitative analyses, distinct cultural models were found showing that the Dutch attributed a bigger role to maturation and children's own pace than to stimulation...
March 5, 2018: Developmental Psychology
K El Kinany, M Deoula, Z Hatime, B Bennani, K El Rhazi
BACKGROUND: This systematic review was conducted to explain the association between dairy products and colorectal cancer (CRC) risk in Middle Eastern and North African countries (MENA). METHODS: The database consulted were PubMed, Clinical Trials, and Cochrane to extract the relevant studies published till the 31stof December 2016, using inclusion and exclusion criteria according to Prisma Protocol. The characteristics of these studies comprised the consumption of all types of dairy products in relation to CRC risk...
March 1, 2018: BMC Cancer
Daniela Siqueira Prado, Rosemar Barbosa Mendes, Rosana Queiroz Gurgel, Ikaro Daniel de Carvalho Barreto, Felipa Daiana Bezerra, Rosana Cipolotti, Ricardo Queiroz Gurgel
OBJECTIVE: To describe practices and interventions used during labor and childbirth and factors associated with such practices in puerperae in the state of Sergipe. METHOD: A cross-sectional study with 768 postpartum women from 11 maternity hospitals interviewed 6 hours after delivery, and hospital records review. The associations between best practices and interventions used during labor and delivery with exposure variables were described using simple frequencies, percentages, crude and adjusted odds ratio (ORa) with the confidence interval...
December 2017: Revista da Associação Médica Brasileira
Rachel Shirazi, Daniela Ram, Aviya Rakovsky, Efrat Bucris, Yael Gozlan, Yaniv Lustig, Pninit Shaked-Mishan, Orit Picard, Yonat Shemer-Avni, Haim Ben-Zvi, Ora Halutz, Yoav Lurie, Ella Veizman, Matthias Carlebach, Marius Braun, Michal Cohen- Naftaly, Amir Shlomai, Rifaat Safadi, Ella Mendelson, Ella H Sklan, Ziv Ben-Ari, Orna Mor
BACKGROUND: Characteristics of hepatitis B (HBV) and delta (HDV) coinfection in various geographical regions, including Israel, remain unclear. Here we studied HDV seroprevalence in Israel, assessed HDV/HBV viral loads, circulating genotypes and hepatitis delta antigen (HDAg) conservation. METHODS: Serological anti HDV IgG results from 8969 HBsAg positive individuals tested in 2010-2015 were retrospectively analyzed to determine HDV seroprevalence. In a cohort of HBV/HDV coinfected (n=58) and HBV monoinfected (n=27) patients, quantitative real-time PCR (qRT-PCR) and sequencing were performed to determine viral loads, genotypes and hepatitis delta antigen (HDAg) protein sequence...
February 27, 2018: BMC Infectious Diseases
Alba Asensio, Laia Nebot, Lluïsa Estruga, Glòria Perez, Èlia Diez
OBJECTIVE: To describe the knowledge and use of contraceptive methods and health services in the Roma population (Kale/Spanish Gitanos) of two low-income neighbourhoods of Barcelona (2011-2015). METHOD: Mixed. Community setting. 1) Descriptive cross-sectional study. We interviewed with a questionnaire a sample of residents of childbearing age. We compared the knowledge and use of contraception and services by ethnic self-identification and sex with adjusted logistic regression models to obtain adjusted odds ratio (ORa) and 95% confidence interval (95%CI)...
February 22, 2018: Gaceta Sanitaria
Jochen Woicke, Solomon Haile, Jagannatha Mysore, W Michael Peden, Typhaine Lejeune, Thomas Sanderson, Thomas Brodie
Spontaneous findings noted in the eyes of Mauritian cynomolgus monkeys are described and descriptions are supplemented with illustrations. Findings observed after extensive histopathologic examinations (20 to 44 sections per eye) from 20 control, 17 treatment-naive stock monkeys, and 2 findings noted in drug-treated monkeys that were considered to be spontaneous are included. Also included are findings from 361 control monkeys of routine toxicity studies performed at our laboratories, for most of which a standard histopathological examination of 1 section per eye was conducted...
January 1, 2018: Toxicologic Pathology
S Lundin, C F Wahlgren, A Bergström, E K Johansson, E Dahlén, N Andersson, I Kull
BACKGROUND: Knowledge regarding how adolescents treat their eczema is sparse. OBJECTIVES: To explore the use of emollients and topical glucocorticoids in adolescents with eczema in relation to sex and disease severity, and to study dispensing patterns of topical glucocorticoids. METHODS: Questionnaire-based data on symptoms of eczema, eczema severity and treatment with emollients and topical glucocorticoids were obtained from 3,108 adolescents in the Swedish population-based birth cohort BAMSE...
February 25, 2018: British Journal of Dermatology
Hakim Benkhatar, Ora Levy, Isabelle Goemaere, Vincent Borderie, Laurent Laroche, Nacim Bouheraoua
PURPOSE: We describe the first case of minimally invasive corneal neurotization with the great auricular nerve (GAN) to treat unilateral neurotrophic keratopathy. We assessed corneal sensation and reinnervation by esthesiometry and confocal microscopy over 12 months of follow-up, and we provide a detailed description of the surgical technique. METHODS: Corneal neurotization was successfully achieved with the ipsilateral GAN in a 58-year-old woman. Cochet-Bonnet esthesiometry and in vivo confocal microscopy were performed before and after corneal neurotization, to monitor the recovery of corneal sensation and corneal reinnervation by subbasal nerve fibers...
February 22, 2018: Cornea
Geffen Kleinstern, Mor Averbuch, Rania Abu Seir, Riki Perlman, Dina Ben Yehuda, Ora Paltiel
Although autoimmune diseases (AIDs) are known to predispose to non-Hodgkin lymphoma (NHL), their association with NHL prognosis has rarely been investigated. We examined associations between autoimmunity and B-cell NHL onset by comparing AID history (determined by self-report and medication review and supplemented by chart review where possible) among 435 adult B-NHL patients in Hadassah-Hebrew University Medical Center, diagnosed 2009-2014, and 414 age-and-sex frequency-matched controls. We examined AIDs as a whole, B- and T-cell-mediated AIDs, and autoimmune thyroid diseases...
February 22, 2018: Hematological Oncology
Sergei Vlassov, Sven Oras, Mikk Antsov, Jelena Butikova, Rünno Lõhmus, Boris Polyakov
High surface energy of individual nanostructures leads to high adhesion and static friction that can completely hinder the operation of nanoscale systems with movable parts. For instance, silver or gold nanowires cannot be moved on silicon substrate without plastic deformation. In this paper we experimentally demonstrate the operational prototype of low-friction nano-joint. The movable part of the prototype is made either from gold or silver nano-pin produced by laser-induced partial melting of silver and gold nanowires resulting in formation of rounded bulbs on their ends...
February 22, 2018: Nanotechnology
Adriana de Araujo Pinho, Regina Maria Barbosa, Sandra Brignol, Wilza Villela, Simone Souza Monteiro
The advances on HIV/AIDS diagnosis and treatment have enabled people living with HIV/AIDS (PLHA) better quality of life. However, the persistence of HIV-related stigma and discrimination, and the risks triggered by HIV disclosure, may be a barrier to the sexual exercise of PLHA. We investigated the prevalence of sexual inactivity and the reasons given for it among a representative sample of women of reproductive age living with HIV/AIDS (WLWHA) in the municipality of São Paulo, Brazil. We surveyed 918 WLWHA with probability proportional to average number of visits in each of the 18 referral HIV/AIDS services...
February 21, 2018: Archives of Sexual Behavior
Blake Miller, Nathalie Selevsek, Jonas Grossman, Tanya Kilminster, Tim Scanlon, Matthew Daniels, Paolo Nanni, John Milton, Chris Oldham, Johan Greef, Aspinas Chapwanya, Don Bergfelt, André M de Almeida
The effect of feed restriction on the liver protein profiles of two different breeds of sheep was studied. We compared Merino with the Damara, breeds with respectively low and high tolerance to nutritional stress. Each breed was grouped into two nutritional treatments: restricted (12-14% loss of live weight) and control (maintenance). The trial lasted 42 days. Animals were sacrificed and liver samples subjected to label free shotgun proteomics. The resultant proteins had both their fold change and statistical significance in an unpaired t-test calculated to identify differential protein abundance...
February 18, 2018: Journal of Proteomics
Margarita Alegria, Ora Nakash, Kirsten Johnson, Andrea Ault-Brutus, Nicholas Carson, Mirko Fillbrunn, Ye Wang, Alice Cheng, Treniece Harris, Antonio Polo, Alisa Lincoln, Elmer Freeman, Benjamin Bostdorf, Marcos Rosenbaum, Claudia Epelbaum, Martin LaRoche, Ebele Okpokwasili-Johnson, MaJose Carrasco, Patrick E Shrout
Importance: Few randomized clinical trials have been conducted with ethnic/racial minorities to improve shared decision making (SDM) and quality of care. Objective: To test the effectiveness of patient and clinician interventions to improve SDM and quality of care among an ethnically/racially diverse sample. Design, Setting, and Participants: This cross-level 2 × 2 randomized clinical trial included clinicians at level 2 and patients (nested within clinicians) at level 1 from 13 Massachusetts behavioral health clinics...
February 21, 2018: JAMA Psychiatry
Shuichiro Aoki, Hiroshi Murata, Masato Matsuura, Yuri Fujino, Shunsuke Nakakura, Yoshitaka Nakao, Yoshiaki Kiuchi, Ryo Asaoka
Corneal hysteresis (CH) measured with Ocular Response Analyzer (Reichert: ORA) has been reported to be closely related to the glaucomatous visual field (VF) progression. The air pulse applied to an eye not only induces corneal deformation, but also whole eye motion (WEM), which may result in an inaccurate measurement of CH. Here we investigated the influence of air pulse-driven WEM measured with the Corivs ST (CST ® , OCULUS) on the relationship between CH and VF progression in primary open angle-glaucoma patients...
February 14, 2018: Scientific Reports
Pascale Salameh, Mirna Chahine, Souheil Hallit, Rita Farah, Rouba Karen Zeidan, Roland Asmar, Hassan Hosseiny
Hypertension is a risk factor of several diseases, linked to high mortality and morbidity, particularly in developing countries. Some studies have linked indoor and outdoor pollution exposure items to hypertension, but results were inconsistent. Our objective was to assess the association of living conditions related to air pollution to hypertension in Lebanon, a Middle Eastern country. A national cross-sectional study was conducted all over Lebanon. Blood pressure and its related medications were assessed to be able to classify participants as hypertensive or not...
February 13, 2018: Environmental Science and Pollution Research International
J Martin Collinson, Nils O Lindström, Carlos Neves, Karen Wallace, Caroline Meharg, Rebecca H Charles, Zoe K Ross, Amy M Fraser, Ivan Mbogo, Kadri Oras, Masaru Nakamoto, Simon Barker, Suzanne Duce, Zosia Miedzybrodzka, Neil Vargesson
Genetic factors underlying the human limb abnormality congenital talipes equinovarus ('clubfoot') remain incompletely understood. The spontaneous autosomal recessive mouse 'peroneal muscular atrophy' mutant (PMA) is a faithful morphological model of human clubfoot. In PMA mice, the dorsal (peroneal) branches of the sciatic nerves are absent. In this study, the primary developmental defect was identified as a reduced growth of sciatic nerve lateral motor column (LMC) neurons leading to failure to project to dorsal (peroneal) lower limb muscle blocks...
February 8, 2018: Development
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"