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https://www.readbyqxmd.com/read/28925766/correlation-of-types-of-food-and-asthma-diagnosis-in-childhood-a-case-control-study
#1
Souheil Hallit, Chantal Raherison, Rita Abou Abdallah, Rabih Hallit, Pascale Salameh
BACKGROUND: Studies concerning asthma in Lebanon investigated environmental and personal factors but none of them took into account the effect of nutritional habits. Our objective is to assess the effect of nutritional habits on asthma and allergies in Lebanese children aged between 3-16 years old. METHODS: This is a case-control study, conducted between December 2015 and April 2016. The Food Frequency Questionnaire was composed of 16 semi-quantitative questions covering different food categories...
September 19, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28905823/refractive-outcomes-of-intraoperative-wavefront-aberrometry-versus-optical-biometry-alone-for-intraocular-lens-power-calculation
#2
Zina Zhang, Logan William Thomas, Szu-Yen Leu, Steven Carter, Sumit Garg
PURPOSE: To compare the outcomes of intraoperative wavefront aberrometry versus optical biometry alone for intraocular lens (IOL) power calculation in eyes undergoing cataract surgery with monofocal IOL implantation. METHODS: Preoperative data were obtained with the IOLMaster. Intraoperative aphakic measurements and IOL power calculations were obtained in some patients with the optiwave refractive analysis (ORA) system. Analysis was performed to determine the accuracy of monofocal IOL power prediction and postoperative manifest refraction at 1 month of the ORA versus IOLMaster...
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28901817/treatment-and-prognosis-of-stage-i-follicular-lymphoma-in-the-modern-era-does-pet-matter
#3
Ohad S Bentur, Ronit Gurion, Anat Gafter-Gvili, Moshe Gatt, Lev Shvidel, Netanel A Horowitz, Ron Ram, Yair Herishanu, Nadav Sarid, Ora Paltiel, Chezi Ganzel, Natalia Kreiniz, Najib Dally, Odit Gutwein, Pia Raanani, Irit Avivi, Chava Perry
Follicular lymphoma (FL) is the most common subtype of indolent non-Hodgkin lymphoma. Patients with stage I disease are usually treated with radiotherapy (RT). In previous studies, mostly from the pre positron emission tomography-computed tomography (PET-CT) era, the 5 year progression-free survival (PFS) and overall survival (OS) rates of stage I disease were 60-80% and 80-93%, respectively. This study retrospectively evaluated the outcome of stage I FL which was treated with involved field RT in the PET-CT era between 2002 and 2015...
September 13, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28900633/clinical-outcomes-in-patients-with-node-negative-breast-cancer-treated-based-on-the-recurrence-score-results-evidence-from-a-large-prospectively-designed-registry
#4
Salomon M Stemmer, Mariana Steiner, Shulamith Rizel, Lior Soussan-Gutman, Noa Ben-Baruch, Avital Bareket-Samish, David B Geffen, Bella Nisenbaum, Kevin Isaacs, Georgeta Fried, Ora Rosengarten, Beatrice Uziely, Christer Svedman, Debbie McCullough, Tara Maddala, Shmuel H Klang, Jamal Zidan, Larisa Ryvo, Bella Kaufman, Ella Evron, Natalya Karminsky, Hadassah Goldberg, Steven Shak, Nicky Liebermann
The 21-gene Recurrence Score® (RS) assay is a validated prognostic/predictive tool in ER + early-stage breast cancer. However, clinical outcome data from prospective studies in RS ≥ 11 patients are lacking, as are relevant real-life clinical practice data. In this retrospective analysis of a prospectively designed registry, we evaluated treatments/clinical outcomes in patients undergoing RS-testing through Clalit Health Services. The analysis included N0 ER + HER2-negative breast cancer patients who were RS-tested from 1/2006 through 12/2010...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/28900632/clinical-outcomes-in-er-her2-node-positive-breast-cancer-patients-who-were-treated-according-to-the-recurrence-score-results-evidence-from-a-large-prospectively-designed-registry
#5
Salomon M Stemmer, Mariana Steiner, Shulamith Rizel, David B Geffen, Bella Nisenbaum, Tamar Peretz, Lior Soussan-Gutman, Avital Bareket-Samish, Kevin Isaacs, Ora Rosengarten, Georgeta Fried, Debbie McCullough, Christer Svedman, Steven Shak, Nicky Liebermann, Noa Ben-Baruch
The Recurrence Score® is increasingly used in node-positive ER+ HER2-negative breast cancer. This retrospective analysis of a prospectively designed registry evaluated treatments/outcomes in node-positive breast cancer patients who were Recurrence Score-tested through Clalit Health Services from 1/2006 through 12/2011 (N = 709). Medical records were reviewed to verify treatments/recurrences/survival. Median follow-up, 5.9 years; median age, 62 years; 53.9% grade 2; 69.8% tumors ≤ 2 cm; 84.5% invasive ductal carcinoma; 42...
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/28888698/-ultra-wide-field-imaging-of-a-retinal-detachment-caused-by-desinsertion-of-the-ora-serrata
#6
T Grenet, A Giocanti-Aurégan
No abstract text is available yet for this article.
September 6, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28881549/-study-on-the-immunogenicity-and-safety-of-recombinant-b-subunit-whole-cell-cholera-vaccine-infused-with-antacids-in-healthy-population-at-ages-of-2-6-years
#7
T Huang, R C Li, D P Liu
Objective: To assess the immunogenicity and safety of recombinant B-subunit/whole cell cholera vaccine (rBS/WC) oral cholera vaccine (Ora Vacs) infused with antacids in healthy population at ages of 2-6 years. Methods: Between December 2009 and January 2010, we recruited 900 volunteers aged 2-6 years od through giving out recruitment notice for the eligible children's parents from different vaccination clinics of Chongzuo city in Guangxi Zhuang Autonomous Region. This study was a randomized, double-blind, placebo-controlled trial, and subjects were randomly (2∶1) assigned to receive Cholera vaccine infused with antacids or placebo, and observed for safety...
September 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28877634/certolizumab-an-anti-tnf-safe-during-pregancy-the-crib-study-results-an-interview-with-professor-xavier-mariette
#8
Xavier Mariette
Professor Xavier Mariette, MD, PhD, has served as the Head of the Rheumatology Department of Bicêtre Hospital, Paris-Sud University since 1999, a role he took following 10 years of practice of clinical immunology. Professor Mariette has initiated a number of clinical research studies on biotherapies in autoimmune diseases. He is the head of the French RATIO (Research Axed on Tolerance of Biotherapy) observatory, collecting specific rare serious adverse events in patients treated with anti-TNF. He initiated the French AIR (Autoimmunity and Rituximab) and ORA (Orencia and Rheumatoid arthritis) registries of patients with autoimmune diseases treated with rituximab and abatacept...
September 2017: Immunotherapy
https://www.readbyqxmd.com/read/28864777/sequence-variation-in-ppp1r13l-results-in-a-novel-form-of-cardio-cutaneous-syndrome
#9
Tzipora C Falik-Zaccai, Yiftah Barsheshet, Hanna Mandel, Meital Segev, Avraham Lorber, Shachaf Gelberg, Limor Kalfon, Shani Ben Haroush, Adel Shalata, Liat Gelernter-Yaniv, Sarah Chaim, Dorith Raviv Shay, Morad Khayat, Michal Werbner, Inbar Levi, Yishay Shoval, Galit Tal, Stavit Shalev, Eli Reuveni, Emily Avitan-Hersh, Eugene Vlodavsky, Liat Appl-Sarid, Dorit Goldsher, Reuven Bergman, Zvi Segal, Ora Bitterman-Deutsch, Orly Avni
No abstract text is available yet for this article.
September 2017: EMBO Molecular Medicine
https://www.readbyqxmd.com/read/28800636/combined-sprint-and-resistance-training-abrogates-age-differences-in-somatotropic-hormones
#10
Maha Sellami, Wissem Dhahbi, Lawrence D Hayes, Johnny Padulo, Fatma Rhibi, Hanen Djemail, Anis Chaouachi
The aim of this investigation was to compare serum growth hormone (GH), insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) in response to a combined sprint and resistance training (CSRT) program in young and middle-aged men.Thirty-eight healthy, moderately trained men participated in this study. Young and middle-aged men were randomly assigned to, a young training group (YT = 10, 21.4±1.2yrs) ora young control group (YC = 9, 21.6±1.8 yrs), a middle-aged training group (MAT = 10, 40...
2017: PloS One
https://www.readbyqxmd.com/read/28799561/retinal-detachment-repair-and-cataract-surgery-in-patients-with-atopic-dermatitis
#11
V Gnana Jothi, S McGimpsey, J A Sharkey, W C Chan
PurposeThe aim of this study is to report a case series of ocular complications including retinal detachment (RD) and cataract in atopic dermatitis (AD) and surgical management involving a majority of Caucasian patients.Patients and methodsThis study is an observational case series, originally designed as an audit. It involves detailed discussion of history, clinical features, and surgical management of patients presenting with retinal detachment and cataracts secondary to severe AD. Six consecutive patients with diagnosis of severe AD requiring posterior segment and cataract surgery were included in the study...
September 2017: Eye
https://www.readbyqxmd.com/read/28797969/bioactive-mesoporous-silica-nanostructures-with-anti-microbial-and-anti-biofilm-properties
#12
Paul Cătălin Balaure, Bianca Boarca, Roxana Cristina Popescu, Diana Savu, Roxana Trusca, Bogdan Ștefan Vasile, Alexandru Mihai Grumezescu, Alina Maria Holban, Alexandra Bolocan, Ecaterina Andronescu
The increasing rate of antibiotic resistant bacteria associated with nosocomial infections in severely ill patients has urged the need for new antibacterial therapies. Nanostructured materials represent emerging innovative approaches to controlled delivery of different antimicrobial drugs. Delivery systems encapsulating natural compounds with antibacterial effects, such as essential oils have shown a great potential. Herein we report the development of SiO2 mesoporous nanosystems loaded with eucalyptus (EUC), orange (ORA), and cinnamon (CIN) essential oils...
August 7, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28796467/anti-glomerular-basement-membrane-antibody-diagnostics-in-a-large-cohort-tertiary-center-should-we-trust-serological-findings
#13
Abdulla Watad, Nicola Luigi Bragazzi, Kassem Sharif, Ora Shovman, Boris Gilburd, Howard Amital, Yehuda Shoenfeld
BACKGROUND: Anti-glomerular basement membrane (GBM) antibody disease, or Goodpasture's disease, is the clinical manifestation of the production of anti-GBM antibodies, which causes rapidly progressive glomerulonephritis with or without pulmonary hemorrhage. Anti-GBM antibody detection is mandatory for the diagnosis of Goodpasture's disease either from the serum or kidney biopsy. Renal biopsy is necessary for disease confirmation; however, in cases in which renal biopsy is not possible or is delayed, serum detection of anti-GBM antibody is the only way for diagnosis...
July 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28793314/patient-satisfaction-after-holmium-laser-enucleation-of-the-prostate-holep-a-prospective-cohort-study
#14
Young Ju Lee, Shin Ah Oh, Sung Han Kim, Seung-June Oh
OBJECTIVE: To investigate patient satisfaction after holmium laser enucleation of the prostate (HoLEP) in a prospective study. SUBJECTS AND METHODS: From May 2012 to December 2014, 397 patients underwent HoLEP by a single surgeon and enrolled in our prospective registry. Baseline data included age, PSA, transrectal ultrasonography, the international prostate symptom score (IPSS), and overactive bladder symptom score (OABSS). Subjective assessment of surgical outcomes was performed at 6 months postoperatively using self-administered questionnaires consisting of 'satisfaction with treatment question' (STQ), 'overall response assessment' (ORA), and 'willingness to undergo surgery question' (WSQ)...
2017: PloS One
https://www.readbyqxmd.com/read/28783680/arc-arg3-1-governs-inflammatory-dendritic-cell-migration-from-the-skin-and-thereby-controls-t-cell-activation
#15
Friederike Ufer, Pablo Vargas, Jan Broder Engler, Joseph Tintelnot, Benjamin Schattling, Hana Winkler, Simone Bauer, Nina Kursawe, Anne Willing, Oliver Keminer, Ora Ohana, Gabriela Salinas-Riester, Ole Pless, Dietmar Kuhl, Manuel A Friese
Skin-migratory dendritic cells (migDCs) are pivotal antigen-presenting cells that continuously transport antigens to draining lymph nodes and regulate immune responses. However, identification of migDCs is complicated by the lack of distinguishing markers, and it remains unclear which molecules determine their migratory capacity during inflammation. We show that, in the skin, the neuronal plasticity molecule activity-regulated cytoskeleton-associated protein/activity-regulated gene 3.1 (Arc/Arg3.1) was strictly confined to migDCs...
September 23, 2016: Science Immunology
https://www.readbyqxmd.com/read/28770702/prevalence-of-anti-dfs70-antibodies-in-patients-with-and-without-systemic-autoimmune-rheumatic-diseases
#16
Ora Shovman, Boris Gilburd, Chen Chayat, Howard Amital, Pnina Langevitz, Abdulla Watad, Adi Guy, Dolores Perez, Danielle Azoulay, Miri Blank, Yael Segal, Chelsea Bentow, Michael Mahler, Yehuda Shoenfeld
OBJECTIVES: Autoantibodies to the dense fine speckled 70 (DFS70) antigen are common among antinuclear antibodies (ANA) positive healthy individuals (HI). We assessed the prevalence of anti-DFS70 antibodies in patients with and without ANA-associated rheumatic diseases (AARDs) by two methods: chemiluminescent immunoassay (CIA) and an indirect immunofluorescence (IIF) assay based on immunoadsorption for DFS70. METHODS: Fifty-one ANA-positive sera samples from patients with confirmed clinical diagnosis of AARD, 92 samples from HI and 85 samples submitted to a reference laboratory for routine ANA testing were evaluated for the presence of anti-DFS70 antibodies...
July 27, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28767664/bruch%C3%A2-s-membrane-thickness-in-relationship-to-axial-length
#17
Hai Xia Bai, Ying Mao, Ling Shen, Xiao Lin Xu, Fei Gao, Zhi Bao Zhang, Bin Li, Jost B Jonas
PURPOSE: To assess a potential role of Bruch´s membrane (BM) in the biomechanics of the eye, we measured its thickness and the density of retinal pigment epithelium (RPE) cells in various ocular regions in eyes of varying axial length. METHODS: Human globes, enucleated because of an ocular tumor or end-stage glaucoma were prepared for histological examination. Using light microscopy, the histological slides were histomorphometrically examined applying a digitized image analysis system...
2017: PloS One
https://www.readbyqxmd.com/read/28767441/socioeconomic-deprivation-worsens-the-outcomes-of-italian-women-with-hormone-receptor-positive-breast-cancer-and-decreases-the-possibility-of-receiving-standard-care
#18
Francesca Di Salvo, Nicola Caranci, Teresa Spadea, Nicolas Zengarini, Pamela Minicozzi, Hade Amash, Mario Fusco, Fabrizio Stracci, Fabio Falcini, Claudia Cirilli, Giuseppina Candela, Rosanna Cusimano, Rosario Tumino, Milena Sant, For The Socioeconomic Inequalities And Oncological Outcomes Italian Working Group
BACKGROUND: Socioeconomic factors influence access to cancer care and survival. This study investigated the role of socioeconomic status on the risk of breast cancer recurrence and on the delivery of appropriate cancer care (sentinel lymph node biopsy and breast-conserving surgery plus radiotherapy), by patients' age and hormone receptor status. METHODS: 3,462 breast cancer cases diagnosed in 2003-2005 were selected from 7 Italian cancer registries and assigned to a socioeconomic tertile on the basis of the deprivation index of their census tract...
July 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28761329/comparison-of-different-intraocular-pressure-measurement-techniques-in-normal-eyes-and-post-small-incision-lenticule-extraction
#19
Mohamed Hosny, Fayrouz Aboalazayem, Hoda El Shiwy, Mohsen Salem
PURPOSE: The purpose of the study was to determine the accuracy of intraocular pressure (IOP) measurement after small incision lenticule extraction (SMILE) using Goldmann applanation tonometry (GAT) and ocular response analyzer (ORA). METHODS: This is a prospective clinical study that was conducted on 30 eyes in the interval between February 2016 and September 2016. The age of the patients ranged between 19 and 40 years. The patients underwent SMILE surgery using the femto laser...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28760196/effects-of-pep-1-fk506bp-on-cyst-formation-in-polycystic-kidney-disease
#20
Hyo Sang Jo, Won Sik Eum, Eun Young Park, Je Young Ko, Do Yeon Kim, Dae Won Kim, Min Jea Shin, Ora Son, Su Bin Cho, Jung Hwan Park, Chi Hern Lee, Eun Ji Yeo, Hyeon Ji Yeo, Yeon Joo Choi, Jong Kyu Youn, Sung-Woo Cho, Jinseu Park, Jong Hoon Park, Soo Young Choi
Polycystic kidney disease (PKD) is one of the most common inherited disorders, whereby progressive cyst formation in the kidney leads to renal failure. FK506 binding protein 12 (FK506BP) is an immunophilin protein which performs multiple functions including regulation of cell signaling and survival. In this study, we determined the roles of PEP-1-FK506BP on cell proliferation and cyst formation in PKD cells. Purified PEP-1-FK506BP transduced into PKD cells and markedly inhibited cell proliferation. Also, PEP-1-FK506BP drastically inhibited the expression levels of p-Akt, p-p70S6K, p-mTOR, and p-ERK in PKD cells...
July 28, 2017: BMB Reports
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