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https://www.readbyqxmd.com/read/29329869/a-new-equation-for-converting-the-parameter-ec50-into-the-total-antioxidant-capacity-teac-and-vice-versa
#1
Justyna Polak, Mariola Bartoszek
A new equation for converting EC50 into TEAC values and TEAC into EC50 is presented in this paper. The model was fitted to 180 data points of electron paramagnetic resonance (EPR) spectroscopy measurements of various food products. The model was tested basing on 75 EPR spectroscopy measurements. Moreover, the equation was tested on literature data. The determination coefficient between EC50cal and EC50exp was found to be R2 = 0.9762, while the determination coefficient between TEACcal and TEACexp was found to be R2 = 0...
May 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29322347/all-aspect-of-toxic-effect-of-brilliant-blue-and-sunset-yellow-in-allium-cepa-roots
#2
Kemal Koç, Dilek Pandir
Substances added to food are considerable for survival and are the oldest technologies used in preservation, sweetening and coloring. This work was conducted to evaluate the toxicity of the food additives sunset yellow (SY) and brilliant blue (BB) on Allium cepa root meristematic cells. Control and treatment groups were created from germinated roots. Group 1 (control group) did not receive chemicals. Group 2 (SY or BB-treatment group), received increasing doses of SY (25, 50, 100 and 500 ppm) and BB (100, 200, 400 and 500 ppm) with time periods of 24, 48 and 72 h...
January 10, 2018: Cytotechnology
https://www.readbyqxmd.com/read/29321995/anticonvulsant-effect-of-ethanolic-extract-of-cyperus-articulatus-l-leaves-on-pentylenetetrazol-induced-seizure-in-mice
#3
Oscar Herrera-Calderon, Rocio Santiváñez-Acosta, Bertha Pari-Olarte, Edwin Enciso-Roca, Vicente Martin Campos Montes, Jorge Luis Arroyo Acevedo
Cyperus articulatus (CA) rhizomes have demonstrated different properties on nervous system. However, the leaves still have not studied to treat epilepsy. The aim of this study was to determine the effect of CA ethanolic extract on pentylenetetrazol (PTZ) induced seizures in mice as well as measuring its antioxidant activity in vivo and in vitro. Mice were divided into five groups: (1) control (PTZ 80 mg/kg; i.p.), (2) PTZ-Diazepam (1 mg/kg; i.p.), (3-5) PTZ-CA 50, PTZ-CA 150 and PTZ-CA 300 (50, 150 and 300 mg/kg of CA extract, 30 min prior to each PTZ injection)...
January 2018: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/29316619/radical-scavenging-and-anti-inflammatory-activities-of-representative-anthocyanin-groupings-from-pigment-rich-fruits-and-vegetables
#4
Federica Blando, Nadia Calabriso, Helge Berland, Gabriele Maiorano, Carmela Gerardi, Maria Annunziata Carluccio, Øyvind M Andersen
Anthocyanins, the naturally occurring pigments responsible for most red to blue colours of flowers, fruits and vegetables, have also attracted interest because of their potential health effects. With the aim of contributing to major insights into their structure-activity relationship (SAR), we have evaluated the radical scavenging and biological activities of selected purified anthocyanin samples (PASs) from various anthocyanin-rich plant materials: two fruits (mahaleb cherry and blackcurrant) and two vegetables (black carrot and "Sun Black" tomato), differing in anthocyanin content (ranging from 4...
January 6, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29314152/optimization-of-pressurized-liquid-extraction-by-response-surface-methodology-of-goji-berry-lycium-barbarum-l-phenolic-bioactive-compounds
#5
Giusy Tripodo, Elena Ibáñez, Alejandro Cifuentes, Bienvenida Gilbert-Lopez, Chiara Fanali
Pressurized liquid extraction (PLE) has been used for the first time in this work to extract phenolic compounds from Goji berries according to a multilevel factorial design using response surface methodology. The global yield (% w/dw, weight/dry-weight), total phenolic content (TPC), total flavonoid (TF) and antioxidant activity (determined via ABTS assay, expressed as TEAC value) were used as response variables to study the effects of temperature (50-180°C) and green solvent composition (mixtures of ethanol/water)...
January 3, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29310631/acute-effect-of-clitoria-ternatea-flower-beverage-on-glycemic-response-and-antioxidant-capacity-in-healthy-subjects-a-randomized-crossover-trial
#6
Charoonsri Chusak, Thavaree Thilavech, Christiani Jeyakumar Henry, Sirichai Adisakwattana
BACKGROUND: Clitoria ternatea L., a natural food-colorant containing anthocyanin, demonstrated antioxidant and antihyperglycemic activity. The aim of this study was to determine the effects of Clitoria ternatea flower extract (CTE) on postprandial plasma glycemia response and antioxidant status in healthy men. METHODS: In a randomized, crossover study, 15 healthy men (ages 22.53 ± 0.30 years; with body mass index of 21.57 ± 0.54 kg/m2) consumed five beverages: (1) 50 g sucrose in 400 mL water; (2) 1 g CTE in 400 mL of water; (3) 2 g CTE in 400 mL of water; (4) 50 g sucrose and 1 g CTE in 400 mL of water; and (5) 50 g sucrose and 2 g CTE in 400 mL of water...
January 8, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29298537/pharmacological-effects-of-chatuphalatika-in-hyperuricemia-of-gout
#7
Vilasinee Hirunpanich Sato, Bunleu Sungthong, Prasob-Orn Rinthong, Narawat Nuamnaichati, Supachoke Mangmool, Savita Chewchida, Hitoshi Sato
CONTEXT: Chatuphalatika (CTPT), is a Thai herbal formulation mixture of Phyllanthus emblica Linn. (Euphorbiaceae), Terminalia belerica Linn. (Combretaceae), T. chebula and the fruit of T. arjuna (Roxb.) Wight & Arn. CTPT is considered to exert anti-inflammatory and antihyperuricemic effects, but there have been no reports to demonstrate these pharmacological effects in a quantitative manner. OBJECTIVES: To investigate the antioxidative, anti-inflammatory and antihyperuricemic effects of CTPT...
December 2018: Pharmaceutical Biology
https://www.readbyqxmd.com/read/29278023/effect-of-%C3%AE-tocopherol-megadoses-on-hematologic-parameters-and-antioxidant-capacity-of-rats-in-an-ultraendurance-probe
#8
V J Clemente-Suárez, J Mielgo-Ayuso, J L Quiles, A Varela-Lopez, P Aranda
This study was aimed to analyze the effect of two different megadoses of α-tocopherol (vit E) in the antioxidant activity and red and white blood series of Wistar rats after a 180-min ultraendurance probe. Three groups of 10 rats were analyzed; VEAG: acute administration of a megadoses of 5,000 IU/kg of vit E the day before the probe; VECG: chronic administration of 1,000 IU/kg/day of vit E for 6 days before the probe; CG: placebo administration. VEAG presented white cells, red blood cells, hematocrit, hemoglobin values significantly higher than CG and VECG (p < 0...
December 1, 2017: Physiology International
https://www.readbyqxmd.com/read/29195930/chilean-berry-ugni-molinae-turcz-fruit-and-leaves-extracts-with-interesting-antioxidant-antimicrobial-and-tyrosinase-inhibitory-properties
#9
Carol López de Dicastillo, Fernanda Bustos, Ximena Valenzuela, Gracia López-Carballo, Jose M Vilariño, Maria Jose Galotto
The knowledge of the biological properties of fruits and leaves of murta (Ugni molinae Turcz.) has been owned by native Chilean culture. The present study investigated the phenolic content, the antioxidant, antimicrobial and anti-tyrosinase activities of different murta fruit and leaves extracts to approach their uses on future food, pharmaceutical and cosmetic applications. Extractions of murta fruit and leaves were carried out under water, ethanol and ethanol 50%. Phenolic content of these extracts was measured through Folin Ciocalteu test and the antioxidant power by four different antioxidant systems (ORAC, FRAP, DPPH and TEAC assays) owing to elucidate the main mechanism of antioxidant...
December 2017: Food Research International
https://www.readbyqxmd.com/read/29184242/antioxidant-capacity-and-identification-of-bioactive-compounds-of-myrtus-communis-l-extract-obtained-by-ultrasound-assisted-extraction
#10
Paula Pereira, Maria-João Cebola, M Conceição Oliveira, M Gabriela Bernardo Gil
Ultrasound-assisted extraction was used to investigate the polyphenolic compounds, particularly anthocyanins, present in myrtle alcoholic extracts. This type of extract is typical in the making of liqueurs obtained from herbs or plants, especially medicinal plants. The leaf extracts were found to contain flavonoids from the quercetin and myricetin families. Besides these, the berry extracts also showed the presence of anthocyanins, hydrolysable tannins and quinic acid. The antioxidant capacity was studied using the ORAC and TEAC methods and the polyphenol content was measured using the Folin-Ciocalteu method...
December 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29175772/antibacterial-anticandidal-and-antioxidant-properties-of-tanacetum-argenteum-lam-willd-subsp-flabellifolium-boiss-heldr-grierson
#11
Yavuz Bulent Kose, Gokalp Iscan, Fatih Goger, Betul Demirci, Ceren Elmacı
In the present study hydrodistilled essential oil and total methanol extracts of Tanacetum argenteum subsp. flabellifolium have been evaluated for their antimicrobial and antioxidant effects. The chemical composition of the oil and the crude extract were determined by GC/FID, GC/MS and LC/DAD/ESI-MS systems respectively. β-thujone (47.1%), α-pinene (19.1%) and α-thujone (10.5%) were the main compounds of the essential oil while the 5-Ocaffeoylquinic acid, 1,5-O-dicaffeoylquinic acid, 4,5-O-dicaffeoylquinic acid were identified as flavonoid content of the crude extract...
November 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29163733/can-antioxidative-status-be-involved-in-type-1-diabetes
#12
Cintia Castro-Correia, M Luz Maia, Sonia Norberto, Cristina Costa-Santos, M Fatima Barroso, Ana Carvalho, Manuel Fontoura, Valentina Domingues, Conceicao Calhau
Background: Type 1 diabetes mellitus (T1DM) is an autoimmune disease with beta-cell destruction, resulting in insulin deficiency. It is now clear that environmental factors also play a role in disease development. The prevalence of type 1 diabetes in children and young people in Portugal is 0.16% between 0 and 19 years of age. The main cause of death in T1DM is cardiovascular disease, and early endothelial dysfunction is its pathophysiologycal precursor. Hyperglycemia is associated with increased production of free radicals and increased oxidative stress...
December 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29128698/seminal-plasma-antioxidants-are-directly-involved-in-boar-sperm-cryotolerance
#13
Junwei Li, Isabel Barranco, Asta Tvarijonaviciute, Manuel F Molina, Emilio A Martinez, Heriberto Rodriguez-Martinez, Inmaculada Parrilla, Jordi Roca
Boar ejaculates are ejected in fractions with a specific composition in terms of sperm numbers and seminal plasma (SP), which is reflected in the varying sperm cryotolerance observed among different fractions. As boar sperm are particularly sensitive to oxidative stress, this study evaluated the role of SP antioxidants in the observed differences in sperm cryotolerance among ejaculate fractions. Ten ejaculates from five boars were manually collected in fractions: the first 10 mL of the sperm-rich fraction (SRF), the rest of the SRF and the post-SRF...
October 31, 2017: Theriogenology
https://www.readbyqxmd.com/read/29095492/antioxidant-stability-study-of-oregano-essential-oil-microcapsules-prepared-by-spray-drying
#14
Claudia M Asensio, Alejandro J Paredes, Maria P Martin, Daniel A Allemandi, Valeria Nepote, Nelson R Grosso
Release kinetics of the volatile compounds of oregano EO microcapsules and the relation with the antioxidant activity were studied. Different wall material (WM) to core (C) ratios (1:1 and 2:1; WM:C), addition of colloidal silicon dioxide (CSD); and different storage conditions: 23 °C (room temperature; R) and 4 °C (fridge temperature; F) were evaluated for 90 d. Volatile compounds, total phenolic content (TPC), free radical scavenging activity (FRSA), and Trolox equivalent antioxidant capacity (TEAC) were measured...
November 2, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29081892/effect-of-neonatal-exposure-to-poly-ethylene-glycol-block-poly-lactic-acid-nanoparticles-on-oxidative-state-in-infantile-and-adult-female-rats
#15
Monika Dvořáková, Eva Rollerová, Soňa Scsuková, Alžbeta Bujňáková Mlynarčíková, Lucia Laubertová, Ingrid Žitňanová
Our goal was to evaluate the potential health risk of the polymeric NP, poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA), from the view of redox imbalance of the organism in two different life stages. Female Wistar rats were neonatally administered intraperitoneally with PEG-b-PLA NPs [20 mg/kg of b.w. (PEG20) or 40 (PEG40) mg/kg of b.w.] from postnatal day 4 (PND4) to PND7. We measured antioxidant capacity (TEAC), level of protein carbonyls and lipoperoxides in plasma, activities of catalase, glutathione peroxidase (GPx), and superoxide dismutase (SOD) in hemolysates of infantile (sacrificed on PND17) and adult (sacrificed after PND176) rats...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28994714/inhibition-of-5%C3%AE-reductase-il-6-secretion-and-oxidation-process-of-equisetum-debile-roxb-ex-vaucher-extract-as-functional-food-and-nutraceuticals-ingredients
#16
Wantida Chaiyana, Chanun Punyoyai, Suvimol Somwongin, Pimporn Leelapornpisid, Kornkanok Ingkaninan, Neti Waranuch, Jukkarin Srivilai, Natthawut Thitipramote, Wudtichai Wisuitiprot, Roswitha Schuster, Helmut Viernstein, Monika Mueller
This study aims to investigate the biological activities related to hair loss of Equisetum debile extracts, including 5α-reductase inhibition, interleukin-6 (IL-6) secretion reduction, and anti-oxidation. E. debile extracts were obtained by maceration in various solvents. Crude extract (CE) was obtained by maceration in 95% ethanol. Chlorophyll-free extract (CF) was the CE which of the chlorophyll has been removed by electrocoagulation. Hexane extract (HE), ethyl acetate extract (EA), and ethanolic extract (ET) were fraction extracts obtained from maceration in hexane, ethyl acetate, and 95% ethanol, respectively...
October 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28992569/4-alkyliden-azetidinones-modified-with-plant-derived-polyphenols-antibacterial-and-antioxidant-properties
#17
Daria Giacomini, Rosario Musumeci, Paola Galletti, Giulia Martelli, Lorenzo Assennato, Gianni Sacchetti, Alessandra Guerrini, Enrico Calaresu, Marianna Martinelli, Clementina Cocuzza
Antimicrobial resistance is one of the major and growing concerns in hospital- and community acquired infections, and new antimicrobial agents are therefore urgently required. It was reported that oxidative stress could contribute to the selection of resistant bacterial strains, since reactive oxygen species (ROS) revealed to be an essential driving force. In the present work 4-alkylidene-azetidinones, a new class of antibacterial agents, were functionalized with phytochemical polyphenolic acids such as protocatechuic, piperonyl, caffeic, ferulic, or sinapic acids and investigated as dual target antibacterial-antioxidant compounds...
September 23, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28987365/anti-oxidant-activity-and-major-chemical-component-analyses-of-twenty-six-commercially-available-essential-oils
#18
Hsiao-Fen Wang, Kuang-Hway Yih, Chao-Hsun Yang, Keh-Feng Huang
This study analyzed 26 commercially available essential oils and their major chemical components to determine their antioxidant activity levels by measuring their total phenolic content (TPC), reducing power (RP), β-carotene bleaching (BCB) activity, trolox equivalent antioxidant capacity (TEAC), and 1,1-diphenyl-2-picrylhydrazyl free radical scavenging (DFRS) ability. The clove bud and thyme borneol essential oils had the highest RP, BCB activity levels, and TPC values among the 26 commercial essential oils...
October 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28958514/identification-and-quantification-of-flavonoids-in-yellow-grain-mutant-of-rice-oryza-sativa-l
#19
Backki Kim, Sunmin Woo, Mi-Jung Kim, Soon-Wook Kwon, Joohyun Lee, Sang Hyun Sung, Hee-Jong Koh
Flavonoids are naturally occurring phenolic compounds with potential health-promoting activities. Although anthocyanins and phenolic acids in coloured rice have been investigated, few studies have focused on flavonoids. Herein, we analysed flavonoids in a yellow grain rice mutant using UHPLC-DAD-ESI-Q-TOF-MS, and identified 19 flavonoids by comparing retention times and accurate mass measurements. Among them, six flavonoids, isoorientin, isoorientin 2″-O-glucoside, vitexin 2″-O-glucoside, isovitexin, isoscoparin 2″-O-glucoside and isoscoparin, were isolated and fully identified from the yellow grain rice mutant, and the levels were significantly higher than wild-type, with isoorientin particularly abundant in mutant embryo...
February 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28955795/extraction-efficiency-phytochemical-profiles-and-antioxidative-properties-of-different-parts-of-saptarangi-salacia-chinensis-l-an-important-underutilized-plant
#20
Dhanaji M Ghadage, Parthraj R Kshirsagar, Sandeep R Pai, Jaykumar J Chavan
The study aimed to evaluate extraction efficiency, detection and quantification of phytochemicals, minerals and antioxidative capacity of different parts of Salacia chinensis L. Continuous shaking extraction, steam bath assisted extraction, ultrasonic extraction and microwave assisted extraction with varied time intervals were employed for extraction of phenolics, flavonoids, and antioxidants. Preliminary screening revealed the presence of wide array of metabolites along with carbohydrates and starch. Steam bath assisted extraction for 10 min exposure was found most suitable for extraction phenolics (46...
December 2017: Biochemistry and Biophysics Reports
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