keyword
https://read.qxmd.com/read/38545418/an-in-vitro-analysis-of-an-innovative-standardized-phospholipid-carrier-based-melissa-officinalis-l-extract-as-a-potential-neuromodulator-for-emotional-distress-and-related-conditions
#1
JOURNAL ARTICLE
Mehtap Kara, Sumeyye Sahin, Fazle Rabbani, Ezgi Oztas, Gozde Hasbal-Celikok, Ebru Kanımdan, Abdurrahim Kocyigit, Ayesha Kanwal, Ursula Wade, Anastasia Yakunina, Francesco Di Pierro, Amjad Khan
Background: Melissa officinalis L. (MO), commonly known as lemon balm, a member of the mint family, is considered a calming herb. In various traditional medicines, it has been utilized to reduce stress and anxiety and promote sleep. A growing body of clinical evidence suggests that MO leaf extract supplementation possesses considerable neuropharmacological properties. However, its possible mechanism of action largely remains unknown. Objective: In the present in vitro studies, we comparatively investigated the central nervous system (CNS)-calming and antioxidative stress properties of an innovative standardized phospholipid carrier-based (Phytosome™) MO extract (Relissa™) vs...
2024: Frontiers in Molecular Biosciences
https://read.qxmd.com/read/38542158/antioxidant-anti-diabetic-and-anti-inflammation-activity-of-garcinia-livingstonei-aqueous-leaf-extract-a-preliminary-study
#2
JOURNAL ARTICLE
Murendeni Nethengwe, Nasifu Kerebba, Kunle Okaiyeto, Chinyerum S Opuwari, Oluwafemi O Oguntibeju
Diabetes mellitus (DM) is the second leading cause of mortality globally. The increased concern for DM is due to the underlying complications accompanying hyperglycaemia, associated with oxidative stress and consequent inflammation. The investigation of safe and effective treatments for DM is necessary. In the present study, the cytotoxicity, phytochemical analysis, antioxidant capacity, anti-inflammatory, and antidiabetic effects in an aqueous extract of Garcinia livingstonei leaves were assessed. All tested extract concentrations showed no toxicity against C3A hepatocytes...
March 10, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38539855/impact-of-seminal-plasma-antioxidants-on-dna-fragmentation-and-lipid-peroxidation-of-frozen-thawed-horse-sperm
#3
JOURNAL ARTICLE
Jaime Catalán, Iván Yánez-Ortiz, Marc Torres-Garrido, Jordi Ribas-Maynou, Marc Llavanera, Isabel Barranco, Marc Yeste, Jordi Miró
Cryopreservation is a stressful process for sperm, as it is associated with an increased production of reactive oxygen species (ROS). Elevated ROS levels, which create an imbalance with antioxidant capacity, may result in membrane lipid peroxidation (LPO), protein damage and DNA fragmentation. This study aimed to determine whether the membrane LPO and DNA fragmentation of frozen-thawed horse sperm relies upon antioxidant activity, including enzymes (superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT) and paraoxonase type 1 (PON1)); non-enzymatic antioxidant capacity (Trolox-equivalent antioxidant capacity (TEAC), plasma ferric reducing antioxidant capacity (FRAP) and cupric reducing antioxidant capacity (CUPRAC)); and the oxidative stress index (OSI) of their seminal plasma (SP)...
March 6, 2024: Antioxidants (Basel, Switzerland)
https://read.qxmd.com/read/38518703/esophageal-adenocarcinoma-heterogeneity-in-clinicopathology-and-prognosis-a-single-center-longitudinal-study-of-146-cases-over-a-20-year-period
#4
JOURNAL ARTICLE
Qin Huang, Edward Lew, Yuqing Cheng, Shweta Shinagare, Vikram Deshpande, Jason S Gold, Daniel Wiener, H Christian Weber
Recent genomic studies suggest that esophageal adenocarcinoma (EAC) is not homogeneous and can be divided into true (tEAC) and probable (pEAC) groups. We compared clinicopathologic and prognostic features between the two groups of EAC. Based on endoscopic, radiologic, surgical, and pathologic reports, tumors with epicenters beyond 2 cm of the gastroesophageal junction (GEJ) were assigned to the tEAC group (N = 63), while epicenters within 2 cm of, but not crossing the GEJ, were allocated to the pEAC group (N = 83)...
February 27, 2024: Annals of Diagnostic Pathology
https://read.qxmd.com/read/38497014/colorimetric-sensing-of-antioxidant-capacity-via-auric-acid-reduction-coupled-to-abts-oxidation
#5
JOURNAL ARTICLE
Burcu Bekdeşer, Reşat Apak
In this study, a simple and sensitive colorimetric assay has been developed for total antioxidant capacity measurement. The assay is based on the absorption measurement of the bluish-green oxidized product (ABTS·+ ) formed as a result of the oxidation reaction of the chromogenic reagent ABTS (2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) with gold(III). However, in the presence of antioxidants, the ABTS oxidation process is effectively suppressed due to the reduction of gold(III) ions to the zerovalent state forming gold nanoparticles (AuNPs)...
March 12, 2024: ACS Omega
https://read.qxmd.com/read/38472908/bee-bread-as-a-functional-product-phenolic-compounds-amino-acid-sugar-and-organic-acid-profiles
#6
JOURNAL ARTICLE
Aksem Aksoy, Sema Sandıkçı Altunatmaz, Filiz Aksu, Nazan Tokatlı Demirok, Kemal Yazıcı, Seydi Yıkmış
Bee bread (perga) is a natural bee product formed by the fermentation of the pollen collected by bees via lactic acid bacteria and yeasts. This study aims to determine the bioactive compounds, amino acid, sugar, and organic acid profile of bee bread samples collected from the Ardahan province of Türkiye. The highest total phenolic, total flavonoid, and DPPH values in bee bread samples were determined as 18.35 mg GAE/g, 2.82 mg QE/g, and 3.90 mg TEAC/g, respectively. Among phenolic compounds, gallic acid had the highest value at 39...
March 4, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38367517/alkaloid-uptake-pathways-in-renal-tubular-epithelial-cells-from-different-processed-products-of-phellodendri-chinensis-cortex
#7
JOURNAL ARTICLE
Xiu-Tong Ge, Jia-Hui Zhao, Wen-Jing Ren, Yue Zhou, Yang Chen, Shi-Ru Jiang, Tian-Zhu Jia, Hui Gao, Fan Zhang
This study aimed to investigate the absorption of alkaloids from Phellodendri chinensis Cortex (PC) by human renal tubular epithelial cells (HK-2). Cellular uptake and affinity ultrafiltration assays were employed to determine the alkaloid uptake pathway in HK-2 cells. Stemming from the hypothesis that salt-water processed PC introduces these alkaloids into the kidney at a cellular level, this research focused on different processed products of PC that are tailored for renal targeting. Utilizing the UPLC-QqQ-MS method, we quantified variations in the uptake capacity of phellodendrine, magnoflorine, jatrorrhizine, berberrubine, and berberine from raw Phellodendri chinensis Cortex (RPC), salt-water processed Phellodendri chinensis Cortex (SPC), and wine processed Phellodendri chinensis Cortex (WPC) in HK-2 cells...
February 6, 2024: Journal of Pharmaceutical and Biomedical Analysis
https://read.qxmd.com/read/38337921/the-biosynthesis-accumulation-of-phenolic-compounds-and-antioxidant-response-in-lactuca-sativa-l-plants-inoculated-with-a-biofertilizer-based-on-soil-yeast-and-iron-nanoparticles
#8
JOURNAL ARTICLE
Daniela Berríos, Javiera Nahuelcura, Felipe González, Fabiola Peña, Pablo Cornejo, José Pérez-Navarro, Sergio Gómez-Alonso, Antonieta Ruiz
Lettuce is a vegetable that contributes vitamins, minerals, fibre, phenolic compounds and antioxidants to the human diet. In the search for improving production conditions and crop health, the use of microorganisms with plant growth-promoting capabilities, such as soil yeasts (PGPY), in conjunction with nanotechnology could offer sustainable development of agroecosystems. This study evaluated the synthesis of health-promoting bioactive compounds in lettuce under the application of soil yeast and an iron nanoparticle (NP-Fe2 O3 ) encapsulated in alginate beads...
January 28, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38318625/enhancing-the-water-permeability-of-composite-nf-membranes-through-the-incorporation-of-organic-ions-in-the-aqueous-phase
#9
JOURNAL ARTICLE
Shuai Zhou, Huifen Tan, Keke Chen, Xin Cheng, Xiaojuan Huang, Congjie Gao
Composite nanofiltration (NF) membranes prepared using interfacial polymerization (IP) have gained significant attention in the field of wastewater treatment. In this study, sodium camphor sulfonate (CSA-Na) and tetraethylammonium chloride (TEAC) were employed as aqueous phase additives to regulate the diffusion of piperazine (PIP) molecules through electrostatic interactions. The dissociated CSA-Na and TEAC in the aqueous solution formed an organic structure at a certain concentration, restricting the interfacial transport behavior of PIP monomers...
January 31, 2024: RSC Advances
https://read.qxmd.com/read/38317943/inaoside-a-new-antioxidant-phenolic-compound-from-the-edible-mushroom-laetiporus-cremeiporus
#10
JOURNAL ARTICLE
Atsushi Kawamura, Aira Mizuno, Mayuri Kurakake, Akiyoshi Yamada, Hidefumi Makabe
Laetiporus cremeiporus is the edible mushroom distributed in East Asia. It has been reported that an extract of L. cremeiporus exhibited DPPH radical scavenging activity. The aim of this study is to identify the antioxidant compound from L. cremeiporus . Guided by DPPH radical scavenging activity, a new antioxidant phenolic compound inaoside A ( 1 ) and three well-known bioactive compounds 5'- S -methyl-5'-thioadenosine (MTA, 2 ), nicotinamide ( 3 ), and adenosine ( 4 ) were isolated from L. cremeiporus . An antioxidant compound was isolated from L...
February 15, 2024: Heliyon
https://read.qxmd.com/read/38298717/green-3-a-green-extraction-of-green-additives-for-green-plastics
#11
JOURNAL ARTICLE
Vera Muccilli, Anna E Maccarronello, Carolle Rasoanandrasana, Nunzio Cardullo, Martina S de Luna, Maria G G Pittalà, Paolo M Riccobene, Sabrina C Carroccio, Andrea A Scamporrino
PLA/PBAT bioplastic is a commercial biodegradable plastic employed for packaging and several food and agriculture applications. In this regard, properties such as the antioxidant ability to extend food shelf life and light resistance, are of great interest in the production of packaging and mulching films, respectively. These features are obtained by developing blends with pure chemicals and/or natural products as additives. In the present work blend formulations of PLA/PBAT with a walnut shell extract rich in antioxidants were developed and evaluated for their properties in comparison with classic PLA/PBAT...
January 30, 2024: Heliyon
https://read.qxmd.com/read/38254613/yeast-starter-culture-identification-to-produce-of-red-wines-with-enhanced-antioxidant-content
#12
JOURNAL ARTICLE
Giuseppe Romano, Marco Taurino, Carmela Gerardi, Maria Tufariello, Marcello Lenucci, Francesco Grieco
Grape variety, quality, geographic origins and phytopathology can influence the amount of polyphenols that accumulate in grape tissues. Polyphenols in wine not only shape their organoleptic characteristics but also significantly contribute to the positive impact that this beverage has on human health. However, during the winemaking process, the total polyphenol content is substantially reduced due to the adsorption onto yeast wall polymers and subsequent lees separation. Despite this, limited information is available regarding the influence of the yeast starter strain on the polyphenolic profile of wine...
January 18, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38254495/whole-flour-of-purple-maize-as-a-functional-ingredient-of-gluten-free-bread-effect-of-in-vitro-digestion-on-starch-and-bioaccessibility-of-bioactive-compounds
#13
JOURNAL ARTICLE
Luisina Monsierra, Pablo Sebastián Mansilla, Gabriela Teresa Pérez
The growing demand for gluten-free products requires the study of alternatives to produce nutritionally and technologically favorable foods. The aim was to evaluate the content and antioxidant capacity of gluten-free bread enriched with whole flour of purple maize (PM) and how starch and bioaccessibility of antioxidant compounds were modified during in vitro digestion. Gluten-free bread was prepared with the addition of 34%, 50%, and 70% PM, and white maize bread served as control. The content of total polyphenols, anthocyanins, and antioxidant capacity through FRAP and TEAC was measured...
January 6, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38248641/characterization-of-the-antiproliferative-activity-of-sargassum-muticum-low-and-high-molecular-weight-polysaccharide-fractions
#14
JOURNAL ARTICLE
Lara Diego-González, Milena Álvarez-Viñas, Rosana Simón-Vázquez, Herminia Domínguez, Maria Dolores Torres, Noelia Flórez-Fernández
The extract obtained by pressurized hot water extraction from Sargassum muticum , to recover the bioactive compound known as fucoidan, was fractionated using membranes of 100, 50, 30, 10, and 5 kDa, obtaining five retentates and the final permeate. These fractions were characterized for phloroglucinol content, protein content, sulfate content, and trolox equivalent antioxidant capacity (TEAC); apart from oligosaccharides, FTIR and molar mass distribution were also evaluated. Retentates of 100 and 50 kDa showed higher values for phloroglucinol, TEAC, and sulfate content...
December 27, 2023: Marine Drugs
https://read.qxmd.com/read/38247475/ultra-high-resolution-liquid-chromatography-coupled-with-electrospray-ionization-quadrupole-time-of-flight-mass-spectrometry-analysis-of-tessaria-absinthioides-hook-arn-dc-asteraceae-and-antioxidant-and-hypocholesterolemic-properties
#15
JOURNAL ARTICLE
Mariana Rey, María Sol Kruse, Jessica Gómez, Mario J Simirgiotis, Alejandro Tapia, Héctor Coirini
Recently, we reported the chemical profile and the hypocholesterolemic effects of a decoction of Tessaria absinthioides (Hook. & Arn.) DC. (Asteraceae). In this study, we evaluated a methanolic extract (METa) instead. Metabolite profiling was conducted using ultra-high-resolution liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UHPLC-ESI-QTOF-MS), identifying thirty compounds, including flavonoids, phenolic acids, fatty acids, and phorbolesters. Antioxidant properties were assessed through 2,2-diphenyl-1-picrylhydrazyl (DPPH), Trolox equivalent antioxidant activity (TEAC), ferric-reducing antioxidant power (FRAP), and inhibition of lipid peroxidation in erythrocytes (ILP) assays, exhibiting robust antioxidant activity...
December 28, 2023: Antioxidants (Basel, Switzerland)
https://read.qxmd.com/read/38231851/biochemical-profile-and-antioxidant-properties-of-propolis-from-northern-spain
#16
JOURNAL ARTICLE
Eugenia Rendueles, Elba Mauriz, Javier Sanz-Gómez, Ana M González-Paramás, María-E Vallejo-Pascual, Félix Adanero-Jorge, Camino García-Fernández
The antioxidant, anti-inflammatory, and antimicrobial characteristics of propolis, a bioactive compound collected from hives, have prompted its use in the food sector in recent times. This study investigated the physicochemical characteristics, phenolic profile, and antioxidant capacity of 31 propolis extracts collected from Northern Spain. The physicochemical composition (resins, waxes, ashes mineral content, and heavy metals) was within the allowable regulatory limits. The analysis of bioactive compounds enabled the identification of 51 constituents: flavonoids (apigenin, catechin, chrysin, quercetin, and pinocembrin) and phenolic acids (caffeic, ferulic, and coumaric)...
December 1, 2023: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38224551/massive-molecular-motion-in-crystal-leads-to-an-unexpected-helical-covalent-polymer-in-a-solid-state-polymerization
#17
JOURNAL ARTICLE
Ravichandran Khazeber, Gautham S Kana, Kana M Sureshan
We designed a proline-derived monomer with azide and alkene functional groups to enable topochemical ene-azide cycloaddition (TEAC) polymerization. In its crystal, the monomer forms supramolecular helices along the 'a' axis through various non-covalent interactions. Along the 'c' axis, the molecules arrange themselves head-to-tail in a wave-like pattern, positioning the azide and alkene groups of adjacent molecules in close proximity and anti-parallel orientation, complying with Schmidt's criteria for topochemical reaction...
January 15, 2024: Angewandte Chemie
https://read.qxmd.com/read/38219358/use-of-encapsulated-pomegranate-seed-oil-in-novel-coarse-and-nanosized-materials-for-improving-the-storage-life-of-strawberry
#18
JOURNAL ARTICLE
Wael S Hassanein, Raciye Meral, Zafer Ceylan, Marwa M Ahmed, Mustafa Tahsin Yilmaz
Different-sized pomegranate seed oil-based emulsions (coarse (CsP) and nanoemulsions (NsP): 1246 and 325 nm) were successfully prepared. Strawberries treated with NsP and CsP showed a significant decrease (p < 0.05) in yeast-mold counts (TMY) by 1.80 log CFU g-1 , and mesophilic aerobic bacteria counts (TMAB) decreased (p < 0.05) by 0.91 log CFU g-1 , respectively. CsP- and NsP-treated strawberries had a TPC of 74.45 and 82.35 mg GAE kg-1 , respectively, while control samples had a TPC of 44...
January 4, 2024: Food Chemistry
https://read.qxmd.com/read/38212400/supercritical-co-2-extraction-of-naringenin-from-mexican-oregano-lippia-graveolens-its-antioxidant-capacity-under-simulated-gastrointestinal-digestion
#19
JOURNAL ARTICLE
Manuel Adrian Picos-Salas, Nayely Leyva-López, Pedro de Jesús Bastidas-Bastidas, Marilena Antunes-Ricardo, Luis Angel Cabanillas-Bojórquez, Miguel Angel Angulo-Escalante, J Basilio Heredia, Erick Paul Gutiérrez-Grijalva
A supercritical CO2 method was optimized to recover naringenin-rich extract from Mexican oregano (Lippia graveolens), a flavanone with high antioxidant and anti-inflammatory activity. The effect of the extraction parameters like pressure, temperature, and co-solvent on naringenin concentration was evaluated. We used response surface methodology to optimize the naringenin extraction from oregano; the chemical composition by UPLC-MS of the optimized extract and the effect of simulated gastrointestinal digestion on its antioxidant capacity and total phenolic content were also evaluated...
January 11, 2024: Scientific Reports
https://read.qxmd.com/read/38201078/fermented-tea-as-a-food-with-functional-value-its-microbiological-profile-antioxidant-potential-and-phytochemical-composition
#20
JOURNAL ARTICLE
Karolina Jakubczyk, Łukasz Łopusiewicz, Joanna Kika, Katarzyna Janda-Milczarek, Karolina Skonieczna-Żydecka
Kombucha is a fermented tea drink produced by a symbiotic culture of bacteria and yeast, known as SCOBY. Its base has traditionally been black tea, which has been recognized for its health-promoting properties, particularly its antioxidant activity based on its high content of pol-yphenolic compounds. A number of previous studies have demonstrated the equally favourable biochemical and phytochemical composition of green tea. The aim of this study was to analyse and compare the basic biochemical composition, microbiological composition and antioxidant properties of black and green tea-based Kombucha...
December 21, 2023: Foods (Basel, Switzerland)
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