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https://www.readbyqxmd.com/read/28878178/microwave-assisted-extraction-of-natural-antioxidants-from-the-exotic-gordonia-axillaris-fruit-optimization-and-identification-of-phenolic-compounds
#1
Ya Li, Sha Li, Sheng-Jun Lin, Jiao-Jiao Zhang, Cai-Ning Zhao, Hua-Bin Li
Our previous study reported that the fruit of Gordonia axillaris , an edible wild fruit, possessed strong antioxidant activity. In this study, a microwave-assisted extraction (MAE) method was established to extract antioxidants from the fruit of Gordonia axillaris . The influence of five parameters, including ethanol concentration, solvent/material ratio, extraction time, extraction temperature and microwave power, was investigated by single-factor experiments. Three factors, namely ethanol concentration, solvent/material ratio, extraction time, were found to exert a major influence on extraction efficacy, and were further studied by response surface methodology to investigate their interactions...
September 6, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28865617/development-of-new-green-processes-for-the-recovery-of-bioactives-from-phaeodactylum-tricornutum
#2
Bienvenida Gilbert-López, Almudena Barranco, Miguel Herrero, Alejandro Cifuentes, Elena Ibáñez
Two novel extraction techniques, pressurized liquid extraction (PLE) and microwave-assisted solvent extraction (MAE) have been evaluated for the recovery of bioactive compounds from Phaeodactylum tricornutum. Microalga P. tricornutum is rich in polyunsaturated fatty acids (PUFAs), such as EPA, and has a high content of the carotenoid fucoxanthin, which is a valuable pigment with several biological activities. Cells were disrupted at high pressure and then freeze-dried as a previous step to extraction. Additionally, only green solvents as water and ethanol (EtOH) - and mixtures of them - were used...
September 2017: Food Research International
https://www.readbyqxmd.com/read/28811749/acute-cocoa-flavanols-intake-has-minimal-effects-on-exercise-induced-oxidative-stress-and-nitric-oxide-production-in-healthy-cyclists-a-randomized-controlled-trial
#3
Lieselot Decroix, Cajsa Tonoli, Danusa Dias Soares, Amandine Descat, Marie-José Drittij-Reijnders, Antje R Weseler, Aalt Bast, Wilhelm Stahl, Elsa Heyman, Romain Meeusen
BACKGROUND: Cocoa flavanols (CF) can stimulate vasodilation by improved nitric oxide (NO) synthesis and have antioxidant and anti-inflammatory capacities. This study aimed to examine whether acute CF intake can affect exercise-induced changes in antioxidant capacity, oxidative stress, inflammation and NO production, as well as exercise performance and recovery in well-trained cyclists. METHODS: Twelve well-trained male cyclists (mean ± SD age, VO2max: 30 ± 3 years, 63...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28805337/genetic-favoring-of-pheomelanin-based-pigmentation-limits-physiological-benefits-of-coloniality-in-lesser-kestrels-falco-naumanni
#4
Ismael Galván, Virginia Moraleda, Ignacio Otero, Ernesto Álvarez, Ângela Inácio
Pheomelanin contributes to the pigmentation phenotype of animals by producing orange and light brown colors in the integument. However, pheomelanin synthesis in melanocytes requires consumption of glutathione (GSH), the most important intracellular antioxidant. Therefore, a genetic control favoring the production of large amounts of pheomelanin for pigmentation may lead to physiological costs under environmental conditions that promote oxidative stress. We investigated this possibility in the context of breeding coloniality, a reproductive strategy that may affect oxidative stress...
August 14, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28768955/special-issue-symposium-on-the-chemistry-of-terpenes-essential-oils-and-aromatics-teac
#5
Mitsuo Miyazawa, Yoshinori Asakawa
No abstract text is available yet for this article.
2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28768410/synthesis-characterization-and-activity-of-a-triazine-bridged-antioxidant-small-molecule
#6
Paulina Gonzalez, Kristof Pota, Lara Su Turan, Viviana C P da Costa, Giridhar Akkaraju, Kayla N Green
Metal-ion misregulation and oxidative stress continue to be components of the continually evolving hypothesis describing the molecular origins of Alzheimer's disease. Therefore, these features are viable targets for synthetic chemists to explore through hybridizations of metal-binding ligands and antioxidant units. To date, the metal-binding unit in potential therapeutic small molecules has largely been inspired by clioquinol with the exception of a handful of heterocyclic small molecules and open-chain systems...
August 22, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28753316/inhibitory-potential-of-red-cabbage-against-digestive-enzymes-linked-to-obesity-and-type-2-diabetes
#7
Anna Podsędek, Iwona Majewska, Alicja Z Kucharska
Assays of the inhibitory potential against enzymes involved in carbohydrate and lipid digestion (α-amylase, α-glucosidase, and lipase) as well as the total contents of phenolics and anthocyanins, anthocyanin profile, and antioxidant capacity revealed significant differences (p < 0.05) between five varieties of red cabbage. Among the varieties, the highest inhibitory activity against α-glucosidase (IC50 = 3.87 ± 0.12 mg dry weight (DW) of cabbage/mL) and lipase (IC50 = 1.57 ± 0.06 mg DW/mL) was exhibited by the Koda variety, which showed the highest antioxidant capacity in ABTS (Trolox equivalent antioxidant capacity (TEAC) = 141 ± 4...
August 23, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28738692/flavonoid-profile-antioxidant-and-antiglycation-properties-of-retama-sphaerocarpa-fruits-extracts
#8
S Boussahel, F Cacciola, S Dahamna, L Mondello, A Saija, F Cimino, A Speciale, M Cristani
Retama sphaerocarpa occurs in the Mediterranean area of North-east Africa and in the Iberian Peninsula, and grows on a variety of soil types and climatic conditions. Used in Algerian folk medicine, it is a valuable species for revegetation and soil restoration. The aim of this study is to evaluate flavonoid composition and antioxidant and antiglycation properties of methanolic and aqueous extracts from R. sphaerocarpa fruits. HPLC-PDA/ESI-MS was used to identify/quantify flavonoid content. Antioxidant activity was evaluated by Folin-Ciocalteu, ORAC, FRAP, TEAC, and DPPH assays, and antiglycation capability by glucose/fructose-BSA assay...
July 24, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28725621/chemical-composition-acute-toxicity-antioxidant-and-anti-inflammatory-activities-of-moroccan-tetraclinis-articulata-l
#9
Meryem El Jemli, Rabie Kamal, Ilias Marmouzi, Zouhra Doukkali, El Houcine Bouidida, Driss Touati, Rachid Nejjari, Lahcen El Guessabi, Yahia Cherrah, Katim Alaoui
Hydro-distilled essential oil (EO) from the leaves of the western Mediterranean and Moroccan endemic plant Tetraclinis articulata was analyzed by GC/MS and examined for its acute toxicity on mice, in order to establish the safe doses. Furthermore, the anti-Inflammatory activity was evaluated based on carrageenan and trauma induced rats paw edema and the antioxidant potential has been investigated using different methods including DPPH radical-scavenging assay, Trolox equivalent antioxidant capacity (TEAC) and Ferric-reducing antioxidant power assay (FRAP)...
July 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28708113/dietary-phytochemicals-promote-health-by-enhancing-antioxidant-defence-in-a-pig-model
#10
Sophie N B Selby-Pham, Jeremy J Cottrell, Frank R Dunshea, Ken Ng, Louise E Bennett, Kate S Howell
Phytochemical-rich diets are protective against chronic diseases and mediate their protective effect by regulation of oxidative stress (OS). However, it is proposed that under some circumstances, phytochemicals can promote production of reactive oxygen species (ROS) in vitro, which might drive OS-mediated signalling. Here, we investigated the effects of administering single doses of extracts of red cabbage and grape skin to pigs. Blood samples taken at baseline and 30 min intervals for 4 hours following intake were analyzed by measures of antioxidant status in plasma, including Trolox equivalent antioxidant capacity (TEAC) and glutathione peroxidase (GPx) activity...
July 14, 2017: Nutrients
https://www.readbyqxmd.com/read/28672789/evaluating-modern-techniques-for-the-extraction-and-characterisation-of-sunflower-hellianthus-annus-l-seeds-phenolics
#11
Panagiotis Zoumpoulakis, Vassilia J Sinanoglou, Eleni Siapi, George Heropoulos, Charalampos Proestos
Recently there is a great interest in using high energy techniques (HET) which involve microwave or ultrasound-assisted extraction (MAE and UAE) for isolation of natural bioactive compounds from plant foods. Such bioactive compounds are phenolics which were determined from sunflower (Helianthus annuus L.) kernels and hulls (defatted) utilising two different high energy extraction techniques, ultrasound and microwave assisted solvent extraction. All samples were characterised by ultra-high-performance liquid chromatography-electrospray ionization-mass spectrometry (UHPLC-ESI-MS)...
June 24, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/28657207/screening-of-polish-fir-honeydew-honey-using-gc-ms-hplc-dad-and-physical-chemical-parameters-benzene-derivatives-and-terpenes-as-chemical-markers
#12
Piotr M Kuś, Igor Jerković, Zvonimir Marijanović, Carlo I G Tuberoso
GC/MS of headspace solid phase micro extraction (HS-SPME) and solvent extractives along with targeted HPLC-DAD of Polish fir (Abies alba Mill.) honeydew honey (FHH), were used to determine the chemical profiles and potential markers of botanical origin. Additionally, typical physical-chemical parameters were also assigned. The values determined for FHH were: conductivity (1.2 mS/cm), water content (16.7 g/100 g), pH (4.5), and CIE chromaticity coordinates (L* = 48.4, a* = 20.6, b* = 69.7, C* = 72...
June 28, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28645884/investigation-of-the-effects-of-lycium-barbarum-polysaccharides-against-cadmium-induced-damage-in-testis
#13
Maria Vittoria Varoni, Sergio Domenico Gadau, Valeria Pasciu, Elena Baralla, Elisa Serra, Domenico Palomba, Maria Piera Demontis
This study describes the effects of Lycium barbarum polysaccharides (LBP) on testicular damage induced by cadmium (Cd). Adult male rats were i.p. injected with CdCl2 (4mg/Kg, once) with or without LBP pretreatment (300mg/Kg orally, once a day, for 30days). Testis weight, morphological/histological structure and oxidative stress parameters were evaluated. Several adverse effects were observed after CdCl2 injection, with a significant decrease in body/testis weight ratio (P<0.05), gross morphological changes with hyperemia of the parenchyma, increased volume and alteration in the structure of the seminiferous tubules...
August 2017: Experimental and Molecular Pathology
https://www.readbyqxmd.com/read/28628845/serum-antioxidant-capacity-and-oxidative-damage-in-clinical-and-subclinical-canine-ehrlichiosis
#14
Camila Peres Rubio, Zeki Yilmaz, Silvia Martínez-Subiela, Meric Kocaturk, Josefa Hernández-Ruiz, Ebru Yalcin, Asta Tvarijonaviciute, Damián Escribano, Jose Joaquín Ceron
The objective of this study was to evaluate and compare the antioxidant response and the products of oxidative damage analysed by various assays in clinical and subclinical canine monocytic ehrlichiosis (CME). For this purpose, four assays to measure the total serum antioxidant capacity (TAC), such as the cupric reducing antioxidant capacity (CUPRAC), ferric reducing ability of plasma (FRAP), trolox equivalent antioxidant capacity (TEAC) using acidic medium (TEACA), and the TEAC using the horseradish peroxidase (TEACH) were used...
June 12, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28604646/effect-of-supercritical-carbon-dioxide-extraction-parameters-on-the-biological-activities-and-metabolites-present-in-extracts-from-arthrospira-platensis
#15
Diego A Esquivel-Hernández, José Rodríguez-Rodríguez, Sara P Cuéllar-Bermúdez, J Saúl García-Pérez, Elena I Mancera-Andrade, Jade E Núñez-Echevarría, Aura Ontiveros-Valencia, Magdalena Rostro-Alanis, Rebeca M García-García, J Antonio Torres, Wei Ning Chen, Roberto Parra-Saldívar
Arthrospira platensis was used to obtain functional extracts through supercritical carbon dioxide extraction (SFE-CO₂). Pressure (P), temperature (T), co-solvent (CX), static extraction (SX), dispersant (Di) and dynamic extraction (DX) were evaluated as process parameters through a Plackett-Burman design. The maximum extract yield obtained was 7.48 ± 0.15% w/w. The maximum contents of bioactive metabolites in extracts were 0.69 ± 0.09 µg/g of riboflavin, 5.49 ± 0.10 µg/g of α-tocopherol, 524.46 ± 0...
June 12, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28603186/solid-phase-extraction-spectrophotometric-determination-of-total-antioxidant-capacity-in-antioxidant-poor-samples-by-using-the-ferric-ferrozine-method
#16
Kadriye Isil Berker, Dilek Ozyurt, Birsen Demirata, Resat Apak
Ferrozine (FZ) preferentially stabilizes Fe(II) over Fe(III) to raise the ferric reduction potential and oxidize antioxidants. The advantages of the ferric-ferrozine method over other iron-based total antioxidant capacity assays were: (i) higher molar absorptivity and enhanced sensitivity, (ii) lower interference from foreign ions, (iii) wide pH tolerance (iv) additivity of the absorbances for mixtures. Solid-phase extraction (SPE) could be combined with spectrophotometry, because the magenta-colored anionic Fe(II)-FZ complex was quantitatively sorbed on Sephadex QAE A-25 resin...
2017: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/28597598/rosa-rugosa-flavonoids-alleviate-myocardial-ischemia-reperfusion-injury-in-mice-by-suppressing-jnk-and-p38-mapk
#17
Xuehui Zhang, Yuhui Wang, Wanli Shen, Shangzhi Ma, Wen Chen, Rong Qi
OBJECTIVE: Although Rosa rugosa has been applied for preventing coronary artery disease, the pharmacological mechanism is little explored. In this study, the effects and mechanisms of Rosa rugosa flavonoids (RRF) on myocardial ischemia reperfusion injury (MIRI) were investigated. METHODS: Mice were pretreated by intragastric administration of 600 mg/kg RRF for 7 days. Then MIRI was induced by 45 min coronary artery ligation and 3 h reperfusion. Myocardial infarct size (MIS) and histopathology, activities of myocardial enzymes and effects of RRF on inflammation and apoptosis were evaluated...
June 9, 2017: Microcirculation: the Official Journal of the Microcirculatory Society, Inc
https://www.readbyqxmd.com/read/28572932/comparison-of-phenolic-content-and-antioxidant-activities-of-millet-varieties-grown-in-different-locations-in-sri-lanka
#18
Disna Kumari, Terrence Madhujith, Anoma Chandrasekara
Soluble and bound phenolic compounds were extracted from different varieties of millet types namely, finger millet, foxtail, and proso millet cultivated at dry and intermediate climatic zones in Sri Lanka. The extracts were examined for their total phenolic content (TPC), total flavonoid content (TFC), and proanthocyanidin content (PC). The antioxidant activities were meassured by reducing power (RP), trolox equivalent antioxidant capacity (TEAC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, ferrous ion chelating ability (FICA), and using a β carotene linoleate model system...
May 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28560092/comparison-in-antioxidant-and-antitumor-activities-of-pine-polyphenols-and-its-seven-biotransformation-extracts-by-fungi
#19
Hui Li, Zhenyu Wang
Microbial transformation can strengthen the antioxidant and antitumor activities of polyphenols. Polyphenols contents, antioxidant and antitumor activities of pine polyphenols and its biotransformation extracts by Aspergillus niger, Aspergillus oryzae, Aspergillus carbonarius, Aspergillus candidus, Trichodermas viride, Mucor wutungkiao and Rhizopus sp were studied. Significant differences were noted in antioxidant and antitumor activities. The highest antioxidant activities in Trolox equivalent antioxidant capacity (TEAC), DPPH radical scavenging activity, superoxide anion radical scavenging activity, hydroxyl radical scavenging activity, reducing power assay and antitumor activity against LoVo cells were biotransformation extract of Aspergillus carbonarius (BAC), biotransformation extract of Mucor wutungkiao (BMW), biotransformation extract of Aspergillus carbonarius (BAC), biotransformation extract of Aspergillus niger (BAN), biotransformation extract of Aspergillus oryzae (BAO) and BMW, respectively...
2017: PeerJ
https://www.readbyqxmd.com/read/28551238/characterization-of-betalains-saponins-and-antioxidant-power-in-differently-colored-quinoa-chenopodium-quinoa-varieties
#20
Josefa Escribano, Juana Cabanes, Mercedes Jiménez-Atiénzar, Martha Ibañez-Tremolada, Luz Rayda Gómez-Pando, Francisco García-Carmona, Fernando Gandía-Herrero
Quinoa was the traditional grain crop used by the prehispanic civilizations in America. Grains are white, black, yellow, and red-violet and plants are cultivated in vast areas of Peru, Bolivia and Ecuador. The recent description of the betacyanin pigment betanin in red-violet varieties is here further analyzed detecting the presence of amaranthin not previously identified in quinoa grains. Yellow-orange grains are characterized for the first time and up to four different betaxanthins are found to be responsible for this coloration...
November 1, 2017: Food Chemistry
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