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https://www.readbyqxmd.com/read/28317910/enterohemorrhagic-escherichia-coli-pathogenesis-role-of-long-polar-fimbriae-in-peyer-s-patches-interactions
#1
Charlotte Cordonnier, Lucie Etienne-Mesmin, Jonathan Thévenot, Amandine Rougeron, Sandra Rénier, Benoit Chassaing, Arlette Darfeuille-Michaud, Nicolas Barnich, Stéphanie Blanquet-Diot, Valérie Livrelli
Enterohemorrhagic Escherichia coli (EHEC) are major food-borne pathogens whose survival and virulence in the human digestive tract remain unclear owing to paucity of relevant models. EHEC interact with the follicle-associated epithelium of Peyer's patches of the distal ileum and translocate across the intestinal epithelium via M-cells, but the underlying molecular mechanisms are still unknown. Here, we investigated the involvement of Long polar fimbriae (Lpf) in EHEC pathogenesis. Of the 236 strains tested, a significant association was observed between the presence of lpf operons and pathogenicity...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28301896/overstressed-response-to-eif2s3-variants-in-mehmo-syndrome
#2
EDITORIAL
Jacques L Michaud
No abstract text is available yet for this article.
April 2017: Human Mutation
https://www.readbyqxmd.com/read/28297849/continuous-time-limits-of-the-utterance-selection-model
#3
Jérôme Michaud
In this paper we derive alternative continuous time limits of the utterance selection model (USM) for language change [G. J. Baxter et al., Phys. Rev. E 73, 046118 (2006)PLEEE81539-375510.1103/PhysRevE.73.046118]. This is motivated by the fact that the Fokker-Planck continuous time limit derived in the original version of the USM is only valid for a small range of parameters. We investigate the consequences of relaxing these constraints on parameters. Using the normal approximation of the multinomial approximation, we derive a continuous time limit of the USM in the form of a weak-noise stochastic differential equation...
February 2017: Physical Review. E
https://www.readbyqxmd.com/read/28289836/prokaryotic-abundance-and-activity-in-permafrost-of-the-northern-victoria-land-and-upper-victoria-valley-antarctica
#4
Rosabruna La Ferla, Maurizio Azzaro, Luigi Michaud, Gabriella Caruso, Angelina Lo Giudice, Rodolfo Paranhos, Anderson S Cabral, Antonella Conte, Alessandro Cosenza, Giovanna Maimone, Maria Papale, Alessandro Ciro Rappazzo, Mauro Guglielmin
Victoria Land permafrost harbours a potentially large pool of cold-affected microorganisms whose metabolic potential still remains underestimated. Three cores (BC-1, BC-2 and BC-3) drilled at different depths in Boulder Clay (Northern Victoria Land) and one sample (DY) collected from a core in the Dry Valleys (Upper Victoria Valley) were analysed to assess the prokaryotic abundance, viability, physiological profiles and potential metabolic rates. The cores drilled at Boulder Clay were a template of different ecological conditions (different temperature regime, ice content, exchanges with atmosphere and with liquid water) in the same small basin while the Dry Valleys site was very similar to BC-2 conditions but with a complete different geological history and ground ice type...
March 13, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28282543/sudden-cardiac-death-and-sarcoidosis-of-the-heart-in-a-young-patient
#5
Morgane Jotterand, Silke Grabherr, Johannes Alexandre Lobrinus, Katarzyna Michaud
Sarcoidosis is a granulomatous disease of unknown etiology affecting any organ, microscopically characterized by noncaseating granulomata. Cardiac involvement in sarcoidosis has been reported. It might be symptomatic or not and even revealed by sudden death. Heart conduction system is rarely investigated at autopsy, even in cases of sudden cardiac death. We present a case of a 32-year-old woman who died suddenly. The examination of the heart conduction system revealed a cardiac sarcoidosis that could explain the sudden death...
January 25, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28279616/-when-and-how-should-small-bowel-capsule-endoscopy-be-used-in-children
#6
J Viala, L Michaud, M Bellaiche, A Lachaux
Small-bowel capsule endoscopy (CE) has recently been used in children. During the past few years, an intense research activity has defined the advantages and limitations of CE. Its uses have been established in several small-bowel pathologies such as obvious or obscure digestive bleeding, Crohn disease, and hereditary polyposis. Although the absence of biopsy reduces the specificity of CE findings, small-bowel exploration using CE achieves better accuracy in detecting lesions than most radiological examinations...
March 6, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28271356/geometric-modeling-of-hepatic-arteries-in-3d-ultrasound-with-unsupervised-mra-fusion-during-liver-interventions
#7
Maxime Gérard, François Michaud, Alexandre Bigot, An Tang, Gilles Soulez, Samuel Kadoury
PURPOSE: Modulating the chemotherapy injection rate with regard to blood flow velocities in the tumor-feeding arteries during intra-arterial therapies may help improve liver tumor targeting while decreasing systemic exposure. These velocities can be obtained noninvasively using Doppler ultrasound (US). However, small vessels situated in the liver are difficult to identify and follow in US. We propose a multimodal fusion approach that non-rigidly registers a 3D geometric mesh model of the hepatic arteries obtained from preoperative MR angiography (MRA) acquisitions with intra-operative 3D US imaging...
March 7, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28269581/exerciser-for-rehabilitation-of-the-arm-era-development-and-unique-features-of-a-3d-end-effector-robot
#8
Marie-Helene Milot, Mathieu Hamel, Philippe-Olivier Provost, Julien Bernier-Ouellet, Maxime Dupuis, Dominic Letourneau, Simon Briere, Francois Michaud
Stroke is one of the leading causes of disability worldwide. Consequently, many stroke survivors exhibit difficulties undergoing voluntary movement in their affected upper limb, compromising their functional performance and level of independence. To minimize the negative impact of stroke disabilities, exercises are recognized as a key element in post-stroke rehabilitation. In order to provide the practice of exercises in a uniform and controlled manner as well as increasing the efficiency of therapists' interventions, robotic training has been found, and continues to prove itself, as an innovative intervention for post-stroke rehabilitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269005/telehomecare-telecommunication-framework-from-remote-patient-monitoring-to-video-visits-and-robot-telepresence
#9
Pierre Lepage, Dominic Letourneau, Mathieu Hamel, Simon Briere, Helene Corriveau, Michel Tousignant, Francois Michaud
Over the last few years, the number of remote patient monitoring (RPM) products and of videoconferencing systems has exploded. There is also a significant number of research initiatives addressing the use of service robots for assistance in daily living activities. From a technological standpoint, providing telehomecare services is certainly feasible. However, one technological barrier is to have access to a telecommunication platform that can be adapted to address the broad range of specifications and requirements of clinical and telehealth applications...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267460/population-associated-heterogeneity-of-the-digestive-cys-protease-complement-in-colorado-potato-beetle-leptinotarsa-decemlineata
#10
Asieh Rasoolizadeh, Marie-Claire Goulet, Jean-Frédéric Guay, Conrad Cloutier, Dominique Michaud
Herbivorous insects use complex protease complements to process plant proteins, useful to adjust their digestive functions to the plant diet and to elude the antidigestive effects of dietary protease inhibitors. We here assessed whether basic profiles and diet-related adjustments of the midgut protease complement may vary among populations of the insect herbivore Colorado potato beetle (Leptinotarsa decemlineata). Two laboratory colonies of this insect were used as models, derived from insect samples collected in potato fields ∼1200km distant from each other in North America...
March 4, 2017: Journal of Insect Physiology
https://www.readbyqxmd.com/read/28254065/biomechzoo-an-open-source-toolbox-for-the-processing-analysis-and-visualization-of-biomechanical-movement-data
#11
Philippe C Dixon, Jonathan J Loh, Yannick Michaud-Paquette, David J Pearsall
It is common for biomechanics data sets to contain numerous dependent variables recorded over time, for many subjects, groups, and/or conditions. These data often require standard sorting, processing, and analysis operations to be performed in order to answer research questions. Visualization of these data is also crucial. This manuscript presents biomechZoo, an open-source toolbox that provides tools and graphical user interfaces to help users achieve these goals. The aims of this manuscript are to (1) introduce the main features of the toolbox, including a virtual three-dimensional environment to animate motion data (Director), a data plotting suite (Ensembler), and functions for the computation of three-dimensional lower-limb joint angles, moments, and power and (2) compare these computations to those of an existing validated system...
March 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28252367/the-economic-consequences-of-obesity-and-overweight-among-adults-in-quebec
#12
Chantal Blouin, Denis Hamel, Nathalie Vandal, Amadou Diogo Barry, Ernest Lo, Guy Lacroix, Johanne Laguë, Marie-France Langlois, Sylvie Martel, Pierre-Carl Michaud, Louis Pérusse
OBJECTIVES: This article presents the first study of the economic consequences of obesity and overweight in the Canadian province of Quebec. The article examines three types of direct costs: hospitalizations, medical visits and drug consumption; and one type of indirect cost: productivity loss due to disability. METHODS: The National Population Health Survey, conducted in all Canadian provinces by Statistics Canada between 1994 and 2011, provides self-reported longitudinal data for body mass index and the frequency of health care utilization and disability...
March 1, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28248794/intestinal-metaplasia-of-the-esophagus-in-children-with-esophageal-atresia
#13
Helen Hsieh, Adam Frenette, Laurent Michaud, Usha Krishnan, Dorothée Bouron Dal-Soglio, Frederic Gottrand, Christophe Faure
OBJECTIVES: Patients with esophageal atresia/tracheo-esophageal fistula (EA-TEF) can develop Barrett's esophagus as a long-term consequence of their condition. Intestinal metaplasia (IM), a risk factor for developing adenocarcinoma of the esophagus, has not been well characterized in the pediatric population. METHODS: Retrospective review of EA-TEF patients followed at three academic pediatric centers between the years 1997 and 2014. RESULTS: Among 542 children and adolescents, 1...
February 28, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28243770/sudden-aortic-death-proposal-for-a-comprehensive-diagnostic-approach-in-forensic-and-in-clinical-pathology-practice
#14
Hans H de Boer, Fabrice Dedouit, Nina Chappex, Allard C van der Wal, Katarzyna Michaud
BACKGROUNDS: Aortic rupture or dissection as immediate cause of sudden death is encountered in forensic and clinical autopsy practice. Despite a common denominator of 'sudden aortic death' (SAD), we expect that in both settings the diagnostic workup, being either primarily legal or primarily disease related, differs substantially, which may affect the eventual diagnoses. METHODS: We retrospectively reviewed case records of deceased persons who fitted a diagnosis of SAD in the continuous autopsy cohorts in a forensic (Suisse) and a clinical setting (The Netherlands)...
February 27, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28241816/influence-of-socioeconomic-status-on-antipsychotic-prescriptions-among-youth-in-france
#15
Olivier Bonnot, Mélanie Dufresne, Paula Herrera, Emmanuelle Michaud, Jacques Pivette, Anicet Chaslerie, Anne Sauvaget, Caroline Vigneau
BACKGROUND: Recent studies analysing the trends in antipsychotic (AP) prescriptions for children and adolescents have raised concerns regarding the influence of socioeconomic status. Previous findings have also shown variable prescription rates for first-generation (FG) and second-generation (SG) APs. METHOD: Our objectives were to assess the proportion of patients from low-income families receiving APs and the most commonly prescribed APs in France. We conducted a descriptive analysis of AP drugs dispensed during a 1-year period (July 1, 2013-June 30, 2014) in a northwestern region of France with 941,857 subjects less than 18 years old...
February 28, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28228057/intravenous-chlorothiazide-versus-enteral-metolazone-to-augment-loop-diuretic-therapy-in-the-intensive-care-unit
#16
Christopher J Michaud, Kendall C Mintus
BACKGROUND: In cases of loop diuretic resistance in the intensive care unit (ICU), recommendations for a specific second-line thiazide agent are lacking. OBJECTIVE: To compare the effects of intravenous chlorothiazide (CTZ) and enteral metolazone (MET) on urine output (UOP) when added to furosemide monotherapy therapy in critically ill adults. METHODS: This was a retrospective cohort study conducted in the medical, surgical, and cardiothoracic ICUs of a quaternary medical center...
April 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28227836/exerciser-for-rehabilitation-of-the-arm-era-development-and-unique-features-of-a-3d-end-effector-robot
#17
Marie-Helene Milot, Mathieu Hamel, Philippe-Olivier Provost, Julien Bernier-Ouellet, Maxime Dupuis, Dominic Letourneau, Simon Briere, Francois Michaud, Marie-Helene Milot, Mathieu Hamel, Philippe-Olivier Provost, Julien Bernier-Ouellet, Maxime Dupuis, Dominic Letourneau, Simon Briere, Francois Michaud, Philippe-Olivier Provost, Dominic Letourneau, Maxime Dupuis, Marie-Helene Milot, Francois Michaud, Mathieu Hamel, Julien Bernier-Ouellet, Simon Briere
Stroke is one of the leading causes of disability worldwide. Consequently, many stroke survivors exhibit difficulties undergoing voluntary movement in their affected upper limb, compromising their functional performance and level of independence. To minimize the negative impact of stroke disabilities, exercises are recognized as a key element in post-stroke rehabilitation. In order to provide the practice of exercises in a uniform and controlled manner as well as increasing the efficiency of therapists' interventions, robotic training has been found, and continues to prove itself, as an innovative intervention for post-stroke rehabilitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227215/telehomecare-telecommunication-framework-from-remote-patient-monitoring-to-video-visits-and-robot-telepresence
#18
Pierre Lepage, Dominic Letourneau, Mathieu Hamel, Simon Briere, Helene Corriveau, Michel Tousignant, Francois Michaud, Pierre Lepage, Dominic Letourneau, Mathieu Hamel, Simon Briere, Helene Corriveau, Michel Tousignant, Francois Michaud, Simon Briere, Dominic Letourneau, Helene Corriveau, Michel Tousignant, Francois Michaud, Mathieu Hamel, Pierre Lepage
Over the last few years, the number of remote patient monitoring (RPM) products and of videoconferencing systems has exploded. There is also a significant number of research initiatives addressing the use of service robots for assistance in daily living activities. From a technological standpoint, providing telehomecare services is certainly feasible. However, one technological barrier is to have access to a telecommunication platform that can be adapted to address the broad range of specifications and requirements of clinical and telehealth applications...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28223277/ventricular-arrhythmias-and-sudden-death-in-patients-taking-ibrutinib
#19
Benjamin L Lampson, Lijian Yu, Robert J Glynn, Jacqueline C Barrientos, Eric D Jacobsen, Versha Banerji, Jeffrey A Jones, Renata Walewska, Kerry J Savage, Gregory F Michaud, Javid J Moslehi, Jennifer R Brown
No abstract text is available yet for this article.
February 21, 2017: Blood
https://www.readbyqxmd.com/read/28219380/effects-of-nutritional-conditions-on-growth-and-biochemical-composition-of-tetraselmis-sp
#20
Mouna Dammak, Bilel Hadrich, Ramzi Miladi, Mohamed Barkallah, Faiez Hentati, Ridha Hachicha, Céline Laroche, Philippe Michaud, Imen Fendri, Slim Abdelkafi
BACKGROUND: This study aimed to maximize biomass concentration, biomass productivity and biochemical composition of the marine microalga Tetraselmis sp. METHODS: In the current study, Box-Behnken Design was used to model the effect of NaNO3, NaH2PO4, metals and vitamins in the F/2 medium on the growth, total chlorophylls, carotenoids and starch contents. The total chlorophylls content was quantified by spectrophotometry. The FT-IR spectroscopy was used to estimate the biochemical compositions of Tetraselmis sp...
February 20, 2017: Lipids in Health and Disease
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