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Iodine deficiency in children

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https://www.readbyqxmd.com/read/29660100/assessment-of-iodine-nutritional-status-of-school-age-children-in-kolkata-district-of-west-bengal-state-in-post-iodation-scenario
#1
Udayan Bhattacharya, Amar K Chandra
To evaluate the state of iodine nutrition in post-iodation scenario, 3500 children were examined clinically for endemic goitre. Iodine and thiocyanate were measured in 240 urine samples; iodine content in 210 salt samples was measured. Total goitre prevalence was 6.1%. Median urinary iodine level was 21.80 µg/dl, and mean (±SD) urinary thiocyanate was 0.89 ± 0.49 mg/dl. Iodine content of only 11.9% salt samples was below recommended level of 15 ppm, 25.2% was between 15 and 30 ppm and 62.9% was >30 ppm...
April 6, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29659964/universal-salt-iodization-provides-sufficient-dietary-iodine-to-achieve-adequate-iodine-nutrition-during-the-first-1000-days-a-cross-sectional-multicenter-study
#2
Susanne Dold, Michael B Zimmermann, Tomislav Jukic, Zvonko Kusic, Qingzhen Jia, Zhongna Sang, Antonio Quirino, Teofilo O L San Luis, Ralph Fingerhut, Roland Kupka, Arnold Timmer, Greg S Garrett, Maria Andersson
Background: Dietary iodine requirements are high during pregnancy, lactation, and infancy, making women and infants vulnerable to iodine deficiency. Universal salt iodization (USI) has been remarkably successful for preventing iodine deficiency in the general population, but it is uncertain if USI provides adequate iodine intakes during the first 1000 d. Objective: We set out to assess if USI provides sufficient dietary iodine to meet the iodine requirements and achieve adequate iodine nutrition in all vulnerable population groups...
April 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29650436/iodine-nutrition-status-and-prevalence-of-abnormal-tsh-levels-in-schoolchildren-aged-6-7-years-in-the-autonomous-community-of-the-basque-country
#3
Juan José Arrizabalaga, Mercedes Jalón, Mercedes Espada, Mercedes Cañas, José María Arena, Lluís Vila
INTRODUCTION: An epidemiological study conducted between 1988 and 1992 showed iodine deficiency and endemic goiter in the schoolchildren of the autonomous community of the Basque Country. OBJECTIVES: 1) To ascertain the iodine nutrition status of schoolchildren aged 6-7 years, and 2) to estimate the prevalence of abnormal TSH levels in capillary blood. POPULATION AND METHODS: The study was conducted on 497 schoolchildren selected by random sampling...
April 10, 2018: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29643159/role-of-iodine-containing-multivitamins-during-pregnancy-for-children-s-brain-function-protocol-of-an-ongoing-randomised-controlled-trial-the-swiddich-study
#4
Sofia Manousou, Birgitta Johansson, Anna Chmielewska, Janna Eriksson, Kerstin Gutefeldt, Carl-Johan Tornhage, Robert Eggertsen, Helge Malmgren, Lena Hulthen, Magnus Domellöf, Helena Nystrom Filipsson
INTRODUCTION: Iodine is essential for normal brain development. Moderate and severe fetal iodine deficiency results in substantial to serious developmental delay in children. Mild iodine deficiency in pregnancy is associated with neurodevelopmental deficits in the offspring, but evidence from randomised trials is lacking. The aim of the Swedish Iodine in Pregnancy and Development in Children study is to determine the effect of daily supplementation with 150 µg iodine during pregnancy on the offspring's neuropsychological development up to 14 years of age...
April 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29529424/iodine-deficiency-in-pregnancy-still-a-health-issue-for-the-women-of-cassino-city-italy
#5
Chiara Tuccilli, Enke Baldini, Elia Truppa, Bruno D'Auria, Domenico De Quattro, Giovanni Cacciola, Tommaso Aceti, Giovanni Cirillo, Antonio Faiola, Patrizia Indigeno, Lorella D'Aliesio, Fiorella Gazzellone, Marco Bononi, Eleonora D'Armiento, Giovanni Carbotta, Daniele Pironi, Antonio Catania, Salvatore Sorrenti, Salvatore Ulisse
OBJECTIVE: The World Health Organization, the United Nations Children's Fund, and the International Council for the Control of Iodine Deficiency Disorders recommend a median urinary iodine concentration (UIC) in pregnant women between 150 µg/L and 249 µg/L. In the present study, we evaluated whether in the urban area of Cassino (central Italy), after a national salt iodination program (30 mg/kg) was introduced in 2005, the increased demand of iodine during pregnancy was satisfied...
November 27, 2017: Nutrition
https://www.readbyqxmd.com/read/29496904/hypothyroidism-and-iodine-deficiency-in-children-on-chronic-parenteral-nutrition
#6
Chijioke Ikomi, Conrad R Cole, Emily Vale, Marjorie Golekoh, Jane C Khoury, Nana-Hawa Yayah Jones
BACKGROUND AND OBJECTIVES: Iodine is an essential trace element for maintenance of normal thyroid function. Normal thyroid function is a prerequisite for neurocognitive development and growth in children. In the United States, iodine is not routinely added as a trace element in parenteral nutrition (PN). Our objective was to determine the prevalence of iodine deficiency and hypothyroidism in children on chronic PN. METHODS: This was a cross-sectional study of children <17 years of age and using PN for >6 months at a tertiary children's hospital...
April 2018: Pediatrics
https://www.readbyqxmd.com/read/29494520/iodine-status-during-pregnancy-in-a-region-of-mild-to-moderate-iodine-deficiency-is-not-associated-with-adverse-obstetric-outcomes-results-from-the-avon-longitudinal-study-of-parents-and-children-alspac
#7
Barbara Torlinska, Sarah C Bath, Aisha Janjua, Kristien Boelaert, Shiao-Yng Chan
Severe iodine deficiency during pregnancy has been associated with pregnancy/neonatal loss, and adverse pregnancy outcomes; however, the impact of mild-to-moderate iodine insufficiency, though prevalent in pregnancy, is not well-documented. We assessed whether mild iodine deficiency during pregnancy was associated with pregnancy/infant loss, or with other adverse pregnancy outcomes. We used samples and data from the Avon Longitudinal Study of Parents and Children (ALSPAC), from 3140 singleton pregnancies and from a further 42 women with pregnancy/infant loss...
March 1, 2018: Nutrients
https://www.readbyqxmd.com/read/29494508/iodine-as-essential-nutrient-during-the-first-1000-days-of-life
#8
REVIEW
Inés Velasco, Sarah C Bath, Margaret P Rayman
Iodine is an essential micronutrient incorporated into thyroid hormones. Although iodine deficiency can lead to a broad spectrum of disorders throughout life, it is most critical in the early stages of development, as the foetal brain is extremely dependent on iodine supply. During the last two decades, our understanding of thyroid physiology during gestation has substantially improved. Furthermore, thyroid hormone receptors have been identified and characterised in placental and embryonic tissues, allowing us to elucidate the maternal-foetal transfer of thyroid hormones...
March 1, 2018: Nutrients
https://www.readbyqxmd.com/read/29446011/continuously-sustained-elimination-of-iodine-deficiency-a-quarter-of-a-century-success-in-the-islamic-republic-of-iran
#9
H Delshad, P Mirmiran, Z Abdollahi, F Salehi, F Azizi
BACKGROUND: Iodine deficiency and related disorders were very common in Iran prior to 1996, when universal salt iodization (USI) was implemented and in 2000 Iran was declared iodine deficiency disorders (IDD) free. The aim of this study was to evaluate the adequacy of iodine intake by Iranian households in all 30 provinces of Iran, a quarter of a century after the intervention. METHODS: A total of 18,000 school-aged children (8-10 years with mean 8.7 ± 1 year) were included in this study...
February 14, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29413098/status-and-interrelationship-of-toenail-elements-in-pacific-children
#10
Shamshad Karatela, Neil I Ward, Irene Suilan Zeng, Janis Paterson
OBJECTIVE: Elemental deficiencies or in excess effects growth and development. Pacific population are at a disadvantage due to food insecurity as compared to New Zealand European households. This study aims to evaluate the status and interrelationship of elements (essential, non-essential and toxic) in nine-year-old Pacific children who were part of the Pacific Island Families Study living in New Zealand. MATERIALS AND METHODS: This observational study included 278 eligible nine-year-old children...
March 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29402856/evaluation-of-dynamic-thiol-disulphide-homeostasis-in-children-and-adolescents-with-non-autoimmune-subclinical-hypothyroidism
#11
Seyit Ahmet Ucakturk, Murat Alışık, Çagatay Ugur, Selin Elmaogullari, Eda Mengen, Özcan Erel
<br>To evaluate the thiol/disulphide homeostasis in children with non-autoimmune subclinical hypothyroidism. <br> Materials (Subjects) and Methods<br>Thiol-disulphide homeostasis [native thiol-disulphide exchanges (native thiol (SH), disulphide (SS), and total thiol (SS+SH))] was evaluated in 60 children and adolescents who were negative for thyroid auto-antibodies (anti-thyroid peroxidase, anti-thyroglobulin) and had a TSH value higher than 5 mIU/L and in 40 sex- and age-matched healthy control subjects who were negative for thyroid auto-antibodies and had normal TSH levels...
January 25, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/29360482/biomonitoring-equivalents-for-interpretation-of-urinary-iodine
#12
Sean M Hays, Devika Poddalgoda, Kristin Macey, Lesa Aylward, Andy Nong
Iodine is an essential nutrient whose deficiency or excess exposure can cause adverse health effects. The primary sources of iodine exposure in the general population are iodized salt, dairy products, bread and sea food. Urinary iodine concentrations (UIC) have been measured by Canadian Health Measures Survey (CHMS) and US National Health and Nutrition Examination Survey (NHANES). The Institute of Medicine (IOM), the US Agency for Toxic Substances and Disease Registry (ATSDR) and World Health Organization (WHO) have established exposure guidance values for nutrition (IOM Estimated Average Requirement (EAR), Recommended Dietary Allowance (RDA), WHO Recommended Nutrient Intake (RNI)) and toxicity (IOM Tolerable Upper Intake Level (UL); ATSDR Minimal Risk Level (MRL), WHO International Programme on Chemical Safety (IPCS) Tolerable Daily Intake (TDI))...
April 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29335065/effects-of-maternal-marginal-iodine-deficiency-on-interactions-between-cerebellar-bergmann-glia-cells-and-purkinje-cells-in-rat-offspring
#13
Ye Yu, Jing Dong, Yuan Wang, Yi Wang, Hui Min, Zhong Yan Shan, Wei Ping Teng, Jie Chen
Iodine deficiency (ID) during early pregnancy has an adverse effect on children's psychomotor and motor function but the mechanism has not been clarified. Therefore, our aim was to study the effect of maternal marginal ID on cerebellar neurodevelopment and the underlying mechanism. After obtaining marginal ID rats, we examined interactions between Bergmann glia cells (BGs) and Purkinje cells (PCs) using immunofluorescence and expression of the glutamate transporter and receptor by western blot. Our results showed that marginal ID reduced the number of contacted points between BGs and PCs, and disturbed expression of the glutamate transporter and receptor...
December 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/29303778/veganism-as-a-cause-of-iodine-deficient-hypothyroidism
#14
Olga Yeliosof, Lawrence A Silverman
BACKGROUND: Iodine deficiency is the most common cause of acquired hypothyroidism worldwide. Although uncommon in the Western world, the incidence of iodine deficiency may be rising due to the increased use of restrictive diets. CASE PRESENTATION: We present a 23-month-old boy diagnosed with iodine deficiency hypothyroidism, induced by a vegan diet. CONCLUSIONS: This case highlights the risk for iodine deficiency in children on a vegan diet after discontinuation of breast/formula feeding that could lead to acquired hypothyroidism...
January 26, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29284787/endemic-goiter-and-iodine-deficiency-status-among-guinea-bissau-school-age-children
#15
Andre Couto Carvalho, Ana Machado, Adulai Robalo Embalo, Adriano A Bordalo
BACKGROUND/OBJECTIVES: Iodine deficiency disorders are estimated to affect 25% of all school-age children around the world. Current policies concerning iodine deficiency disorders in many countries are not based on robust or recent national data. Our objective was to evaluate the current status of iodine nutrition in Guinea-Bissau (West Africa). SUBJECT/METHODS: A cross-sectional survey including 299 school-age children, aged 6-14 years old, from four distinct regions of Guinea-Bissau across a coast-hinterland gradient (Bolama, Bissau, Cambaju-Bafatá, and Gabú) was performed...
December 28, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29279360/iodine-intake-from-supplements-and-diet-during-pregnancy-and-child-cognitive-and-motor-development-the-inma-mother-and-child-cohort-study
#16
Mario Murcia, Mercedes Espada, Jordi Julvez, Sabrina Llop, Maria-Jose Lopez-Espinosa, Jesus Vioque, Mikel Basterrechea, Isolina Riaño, Llucia González, Mar Alvarez-Pedrerol, Adonina Tardón, Jesús Ibarluzea, Marisa Rebagliato
BACKGROUND: The effect of mild-to-moderate maternal iodine deficiency on the neuropsychological development of their offspring is uncertain. We aimed to assess the association between iodine status during pregnancy and the cognitive and motor development of children at 4-5 years. METHODS: We conducted a prospective cohort study in four Spanish regions with recruitment of pregnant women between 2003 and 2008 and follow-up of their children up to 4-5 years (mean (SD)=4...
March 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29236073/reduced-educational-outcomes-persist-into-adolescence-following-mild-iodine-deficiency-in-utero-despite-adequacy-in-childhood-15-year-follow-up-of-the-gestational-iodine-cohort-investigating-auditory-processing-speed-and-working-memory
#17
Kristen L Hynes, Petr Otahal, John R Burgess, Wendy H Oddy, Ian Hay
There is increasing evidence that even mild gestational iodine deficiency (GID) results in adverse neurocognitive impacts on offspring. It's unclear, however, if these persist long-term and whether they can be ameliorated by iodine sufficiency in childhood. We followed a unique cohort (Gestational Iodine Cohort, n = 266) where gestation occurred during a period of mild population iodine deficiency, with children subsequently growing-up in an iodine replete environment. We investigated whether associations between mild GID and reductions in literacy outcomes, observed at age 9-years, persisted into adolescence...
December 13, 2017: Nutrients
https://www.readbyqxmd.com/read/29219141/biochemical-iodine-deficiency-in-selected-schools-of-aligarh
#18
Mohammad Athar Ansari, Zulfia Khan
The goiter prevalence reflects the iodine deficiency in past while urinary iodine excretion levels (UIEL) gives the current status of iodine nutrition. The study was conducted to assess the status of biochemical iodine deficiency in school children of 1st-5th standard (6-12 years). A total of 907 students of seven schools were included using probability proportional to size method. About 10% of urine samples from total children were tested for UIEL. Statistical analysis was done using SPSS version 20 (IBM SPSS Statistics for Windows, Version 20...
October 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/29184815/transient-hypothyroidism-in-the-newborn-to-treat-or-not-to-treat
#19
REVIEW
Neelakanta Kanike, Ajuah Davis, Prem S Shekhawat
Transient congenital hypothyroidism (CH) refers to a temporary deficiency of thyroid hormone identified after birth, with low thyroxine (T4) and elevated thyrotropin (TSH), which later recovers to improved thyroxine production, typically in first few months of infancy. Approximately 17% to 40% of children diagnosed with CH by newborn screening (NBS) programs were later determined to have transient hypothyroidism. Causes of transient CH are prematurity, iodine deficiency, maternal thyrotropin receptor blocking antibodies, maternal intake of anti-thyroid drugs, maternal or neonatal iodine exposure, loss of function mutations and hepatic hemangiomas...
October 2017: Translational pediatrics
https://www.readbyqxmd.com/read/29172409/prevalence-of-goiter-and-associated-factors-among-schoolchildren-in-northeast-ethiopia
#20
Emebet Tigabu, Kindie Bantie Bekele, Berihun Assefa Dachew
OBJECTIVES: Goiter is a major public health problem, especially in developing countries such as Ethiopia. Hence, this study aimed to assess the prevalence and associated factors of goiter among children in Waghimra Zone, northeast Ethiopia. METHODS: A cross-sectional study was conducted from April 8 to 25, 2015 in northeast Ethiopia. A multistage sampling method was used to select 454 schoolchildren. Data were collected using a pre-tested structured interviewer-administered questionnaire...
2017: Epidemiology and Health
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