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https://www.readbyqxmd.com/read/29028856/ethnicity-and-aging-skin
#1
Andrew F Alexis, Jasmine O Obioha
<p>Aging is a complex process influenced by both extrinsic and intrinsic factors. Premature signs of aging due to cumulative UV exposure represent a major concern of the cosmetic patient. Skin of color is less susceptible to photodamage and thus signs of aging are less pronounced and occur later than in Caucasians. Understanding structural and functional differences among different racial/ethnic groups is important to achieve favorable treatment outcomes when addressing aging concerns.</p> <p><em<J Drugs Dermatol...
June 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29027374/flow-cytometric-monitoring-of-bacterioplankton-phenotypic-diversity-predicts-high-population-specific-feeding-rates-by-invasive-dreissenid-mussels
#2
Ruben Props, Marian L Schmidt, Jasmine Heyse, Henry A Vanderploeg, Nico Boon, Vincent J Denef
Species invasion is an important disturbance to ecosystems worldwide, yet knowledge about the impacts of invasive species on bacterial communities remains sparse. Using a novel approach, we simultaneously detected phenotypic and derived taxonomic change in a natural bacterioplankton community when subjected to feeding pressure by quagga mussels, a widespread aquatic invasive species. We detected a significant decrease in diversity within one hour of feeding, and a total diversity loss of 11.6 ± 4.1 % after 3h...
October 13, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/29025234/clitoral-surgery-after-female-genital-mutilation-cutting
#3
Jasmine Abdulcadir, Omar Abdulcadir, Martin Caillet, Lucrezia Catania, Béatrice Cuzin, Birgitta Essén, Pierre Foldès, Sara Johnsdotter, Crista Johnson-Agbakwu, Nawal Nour, Charlemagne Ouedraogo, Nicole Warren, Sophie Wylomanski
No abstract text is available yet for this article.
October 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29024494/extensive-hyperpigmentation-of-the-face-in-a-filipina
#4
Johanna Pirrone, Jasmin Broyer, Nicola Otte, Kristian Reich, Almut Boer-Auer
No abstract text is available yet for this article.
October 10, 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29023700/teaching-learning-tips-1-teaching-perspectives-an-introduction
#5
Jasmine Rana, Susan Burgin
Challenge: Clinical and research responsibilities often leave little or no time to plan thoughtful teaching encounters with trainees. This "Teaching & Learning Tips" series is designed to be an accessible guide for dermatologists who want to improve their teaching skills. It is comprised of 12 articles about how to enhance teaching in various settings informed by research about how people learn and expert-derived or data-driven best practices for teaching. The series begins with a review of principles to optimize learning in any setting, including cognitive load theory, active learning strategies, and the impact of motivation and emotion on learning...
November 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29022497/estrogen-induced-disruption-of-intracellular-iron-metabolism-leads-to-oxidative-stress-membrane-damage-and-cell-cycle-arrest-in-mcf-7-cells
#6
Khuloud Bajbouj, Jasmin Shafarin, Maher Y Abdalla, Iman M Ahmad, Mawieh Hamad
It is well established that several forms of cancer associate with significant iron overload. Recent studies have suggested that estrogen (E2) disrupts intracellular iron homeostasis by reducing hepcidin synthesis and maintaining ferroportin integrity. Here, the ability of E2 to alter intracellular iron status and cell growth potential was investigated in MCF-7 cells treated with increasing concentrations of E2. Treated cells were assessed for intracellular iron status, the expression of key proteins involved in iron metabolism, oxidative stress, cell survival, growth, and apoptosis...
October 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/29021780/chronic-5-aminoimidazole-4-carboxamide-1-%C3%AE-d-ribofuranoside-treatment-induces-phenotypic-changes-in-skeletal-muscle-but-does-not-improve-disease-outcomes-in-the-r6-2-mouse-model-of-huntington-s-disease
#7
Marie-France Paré, Bernard J Jasmin
Huntington's disease (HD) is an autosomal dominant neurodegenerative genetic disorder characterized by motor, cognitive, and psychiatric symptoms. It is well established that regular physical activity supports brain health, benefiting cognitive function, mental health as well as brain structure and plasticity. Exercise mimetics (EMs) are a group of drugs and small molecules that target signaling pathways in skeletal muscle known to be activated by endurance exercise. The EM 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) has been shown to induce cognitive benefits in healthy mice...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29021237/recommendations-for-collaborative-paediatric-research-including-biobanking-in-europe-a-single-hub-and-access-point-for-paediatric-rheumatology-in-europe-share-initiative
#8
Jasmin B Kuemmerle-Deschner, Sandra Hansmann, Nico M Wulffraat, Sebastiaan J Vastert, Kristien Hens, Jordi Anton, Tadej Avcin, Alberto Martini, Isabelle Koné-Paut, Yosef Uziel, Angelo Ravelli, Carine Wouters, David Shaw, Seza Özen, Andreas Eikelberg, Berent J Prakken, Nicolino Ruperto, Gerd Horneff, Tamas Constantin, Michael W Beresford, Marijn Sikken, Helen E Foster, Iris Haug, Sabrina Schuller, Christine Jägle, Susanne M Benseler
Innovative research in childhood rheumatic diseases mandates international collaborations. However, researchers struggle with significant regulatory heterogeneity; an enabling European Union (EU)-wide framework is missing. The aims of the study were to systematically review the evidence for best practice and to establish recommendations for collaborative research. The Paediatric Rheumatology European Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) project enabled a scoping review and expert discussion, which then informed the systematic literature review...
October 11, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29020159/distinguishing-secondary-dengue-virus-infection-from-zika-virus-infection-with-previous-dengue-by-a-combination-of-three-simple-serological-tests
#9
Wen-Yang Tsai, Han Ha Youn, Carlos Brites, Jih-Jin Tsai, Jasmine Tyson, Celia Pedroso, Jan Felix Drexler, Mars Stone, Graham Simmons, Michael P Busch, Marion Lanteri, Susan L Stramer, Angel Balmaseda, Eva Harris, Wei-Kung Wang
Background: The explosive spread of Zika virus (ZIKV) and associated microcephaly present an urgent need for sensitive and specific serodiagnostic tests, particularly for pregnant women in dengue virus (DENV)-endemic regions. Recent reports of enhanced ZIKV replication by dengue-immune sera have raised concerns about the role of previous DENV infection on the risk and severity of microcephaly and other ZIKV complications. Methods: Enzyme-linked immunosorbent assays (ELISAs) based on ZIKV and DENV non-structural protein 1 (NS1) were established to test acute, convalescent-phase and post-convalescent-phase serum/plasma samples from reverse-transcription polymerase-chain reaction-confirmed-cases including 20 primary ZIKV, 25 ZIKV with previous dengue, 58 secondary DENV, and 16 primary DENV1 infections...
July 29, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29018239/a-blueprint-for-robust-crosslinking-of-mobile-species-in-biogels-with-weakly-adhesive-molecular-anchors
#10
Jay Newby, Jennifer L Schiller, Timothy Wessler, Jasmine Edelstein, M Gregory Forest, Samuel K Lai
Biopolymeric matrices can impede transport of nanoparticulates and pathogens by entropic or direct adhesive interactions, or by harnessing "third-party" molecular anchors to crosslink nanoparticulates to matrix constituents. The trapping potency of anchors is dictated by association rates and affinities to both nanoparticulates and matrix; the popular dogma is that long-lived, high-affinity bonds to both species facilitate optimal trapping. Here we present a contrasting paradigm combining experimental evidence (using IgG antibodies and Matrigel®), a theoretical framework (based on multiple timescale analysis), and computational modeling...
October 10, 2017: Nature Communications
https://www.readbyqxmd.com/read/29016522/spontaneous-resolution-of-delayed-suprachoroidal-hemorrhage-in-the-single-eye-following-needling-in-congenital-glaucoma
#11
Jasmin Rezapour, Esther M Hoffmann, Verena Prokosch-Willing, Adrian Gericke, Norbert Pfeiffer
INTRODUCTION: Suprachoroidal hemorrhage is a rare, but potentially vision-threatening event with poor long-term visual prognosis. At present, there is disagreement whether surgical intervention or conservative treatment is superior in the management. We report on a case of spontaneous resolution of severe SCH after needling procedure in the only eye of a young patient with congenital glaucoma. CASE PRESENTATION: A 43-year-old woman with congenital glaucoma was scheduled for bleb needling in her only eye...
October 9, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29016464/perceptions-of-diabetes-self-care-management-among-older-singaporeans-with-type-2-diabetes-a-qualitative-study
#12
Cherry Chay Lee Tan, Karis Kin Fong Cheng, Chee Fang Sum, Jasmine Sew Hong Shew, Eleanor Holydard, Wenru Wang
BACKGROUND: Given the global shift in aging populations and the associated increasing prevalence of diabetes, it is critical to explore new approaches in diabetic self-care management. In Singapore, what has been overlooked to date is an in-depth, contextually based examination of the needs, expectations, and barriers faced in self-care management by older adults with Type 2 diabetes. PURPOSE: This study aimed to explore the experiences of older Singaporeans with Type 2 diabetes in diabetes self-care management to understand their perceived needs, expectations, and barriers associated with their diabetes self-care management...
October 10, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/28993736/pathogenic-mechanisms-of-bicuspid-aortic-valve-aortopathy
#13
REVIEW
Noor M Yassine, Jasmine T Shahram, Simon C Body
Bicuspid aortic valve (BAV) is the most common congenital valvular defect and is associated with ascending aortic dilation (AAD) in a quarter of patients. AAD has been ascribed both to the hemodynamic consequences of normally functioning and abnormal BAV morphology, and to the effect of rare and common genetic variation upon function of the ascending aortic media. AAD manifests in two overall and sometimes overlapping phenotypes: that of aortic root aneurysm, similar to the AAD of Marfan syndrome; and that of tubular AAD, similar to the AAD seen with tricuspid aortic valves (TAVs)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28992225/a-guideline-for-leaf-senescence-analyses-from-quantification-to-physiological-and-molecular-investigations
#14
Justine Bresson, Stefan Bieker, Lena Riester, Jasmin Doll, Ulrike Zentgraf
Leaf senescence is not a chaotic breakdown but a dynamic process following a precise timetable. It enables plants to economize with their resources and control their own viability and integrity. The onset as well as the progression of leaf senescence are co-ordinated by a complex genetic network that continuously integrates developmental and environmental signals such as biotic and abiotic stresses. Therefore, studying senescence requires an integrative and multi-scale analysis of the dynamic changes occurring in plant physiology and metabolism...
August 1, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28991465/inhibitors-to-overcome-secondary-mutations-in-the-stem-cell-factor-receptor-kit
#15
Helena Kaitsiotou, Marina Keul, Julia Hardick, Thomas Mühlenberg, Julia Ketzer, Christiane Ehrt, Jasmin Krüll, Federico Medda, Oliver Koch, Fabrizio Giordanetto, Sebastian Bauer, Daniel Rauh
In modern cancer therapy, the use of small organic molecules against receptor tyrosine kinases (RTKs) has been shown to be a valuable strategy. The association of cancer cells with dysregulated signaling pathways linked to RTKs represents a key element in targeted cancer therapies. The tyrosine kinase mast/stem cell growth factor receptor KIT is an example of a clinically relevant RTK. KIT is targeted for cancer therapy in gastrointestinal stromal tumors (GISTs) and chronic myelogenous leukemia (CML). However, acquired resistance mutations within the catalytic domain decrease the efficacy of this therapy and are the most common cause of failed therapy...
October 9, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28990635/nurses-communication-of-safety-events-to-nursing-home-residents-and-families
#16
Laura M Wagner, Lena Driscoll, Jasmin L Darlington, Victoria Flores, Julee Kim, Katerina Melino, Hema Doshi Patel, Joanne Spetz
Although communication is an essential part of the nursing process, nurses have little to no formal education in how to best communicate patient safety event (PSE) information to nursing home (NH) residents and their family members. The current mixed-methods study tested an intervention aimed at educating nurses on how to communicate a PSE to residents/family members using a structured communication tool. Nurse participants improved their knowledge of PSE communication, especially about the cause of the event, what they would say to the resident/family member, and future prevention of the PSE...
October 6, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/28988644/longitudinal-study-of-accelerated-long-term-forgetting-in-children-with-genetic-generalized-epilepsy-evidence-of-ongoing-deficits
#17
Jasmin Grayson-Collins, Michael B Gascoigne, Belinda Barton, Richard Webster, Deepak Gill, Suncica Lah
Accelerated long-term forgetting (ALF) is a recently described memory disorder characterised by adequate recall after short, but not long delays. Currently, the prevailing conceptualisation of ALF is of a seizure related phenomenon. The main aim of this study was to assess whether ALF subsides as epilepsy severity and seizures abate in children with genetic generalized epilepsy (GGE). Eighteen children with GGE were compared over time to 29 healthy controls on a range of cognitive measures. The primary outcome was a modified version of the California Verbal Learning Test for Children with a long delay (seven day) recall component...
September 15, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28987365/anti-oxidant-activity-and-major-chemical-component-analyses-of-twenty-six-commercially-available-essential-oils
#18
Hsiao-Fen Wang, Kuang-Hway Yih, Chao-Hsun Yang, Keh-Feng Huang
This study analyzed 26 commercially available essential oils and their major chemical components to determine their antioxidant activity levels by measuring their total phenolic content (TPC), reducing power (RP), β-carotene bleaching (BCB) activity, trolox equivalent antioxidant capacity (TEAC), and 1,1-diphenyl-2-picrylhydrazyl free radical scavenging (DFRS) ability. The clove bud and thyme borneol essential oils had the highest RP, BCB activity levels, and TPC values among the 26 commercial essential oils...
October 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28987194/overview-of-cerebrospinal-fluid-cytology
#19
Jasmin Rahimi, Adelheid Woehrer
Cerebrospinal fluid (CSF) cytology, i.e., the cytologic evaluation of its cellular composition, forms an integral part of the neurologist's armamentarium. Total and differential cell counts provide important first information across a spectrum of pathologic conditions involving the central nervous system and its coverings. CSF samples require immediate processing, ideally within 1 hour from collection. Upon centrifugation cytology is commonly assessed on May-Grunwald-Giemsa stains. Several additional stains are available for the identification of infectious agents such as bacteria or fungi, or the further specification of neoplastic cells by immunocytochemistry...
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28987088/rate-of-hemifusion-diaphragm-dissipation-and-ability-to-form-three-junction-bound-hd-determined-by-lipid-composition
#20
Jasmine M Gardner, Cameron F Abrams
Though the hemifusion diaphragm (HD) is widely accepted as an intermediate in bilayer membrane fusion, lipid contributions toward HD stability and dynamics are still not fully understood. In this paper, we study large, binary, protein-free HD systems at varying compositions of negative intrinsic curvature (NIC) lipids using molecular dynamics (MD) simulations of a solvent-free coarse-grained lipid model. Under MD, initially created HDs are found to relax to three major end states depending on the composition and lipid intrinsic curvature...
October 7, 2017: Journal of Chemical Physics
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