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https://www.readbyqxmd.com/read/29673377/total-hip-arthroplasty-to-treat-acetabular-protrusions-secondary-to-rheumatoid-arthritis
#1
Ping Zhen, Xusheng Li, Shenghu Zhou, Hao Lu, Hui Chen, Jun Liu
BACKGROUND: The treatment of acetabular protrusions during total hip arthroplasty of patients with rheumatoid arthritis is difficult. A lack of bone stock, deficient medial cup support, and medialization of the joint center in those with protrusio acetabuli must be addressed during acetabular reconstruction. The purpose of this study was to assess the short-term clinical results of total hip arthroplasty in patients with severe acetabular protrusions secondary to rheumatoid arthritis...
April 19, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29643694/bone-preserving-techniques-for-explanting-the-well-fixed-cemented-acetabular-component
#2
Jarrad Stevens, Gavin Macpherson, Colin Howie
Background: Removal of a well-fixed, cemented acetabular component at the time of revision hip surgery can be complex. It is essential to remove the implant and cement mantle in a timely fashion while preserving bone stock and osseous integrity. The biomechanical properties of polymethylmethacrylate cement and polyethylene can be utilised to aid with the removal of well cemented implants which are often harder than the surrounding bone. While removal of loose components may be relatively straightforward, the challenge for the revision arthroplasty surgeon often involves the removal of well-fixed implants...
June 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29625641/salvaging-a-failed-proximal-interphalangeal-joint-implant
#3
REVIEW
Francis J Aversano, Ryan P Calfee
Salvaging a failed proximal interphalangeal (PIP) joint implant arthroplasty remains a considerable technical and rehabilitation challenge. Experienced arthroplasty surgeons have reported 70% survival of revision PIP implants at 10 years with 25% of patients requiring subsequent revision surgery. At this time, there is no consensus surgical approach or implant proven superior for revision implant arthroplasty of the PIP joint. Secondary arthrodesis or amputation may be required to salvage the failed PIP implant arthroplasty with compromised bone stock or soft tissue envelopes that are inadequate for implant arthroplasty...
May 2018: Hand Clinics
https://www.readbyqxmd.com/read/29582118/reverse-total-shoulder-arthroplasty-using-helical-blade-to-optimize-glenoid-fixation-and-bone-preservation-preliminary-results-in-thirty-five-patients-with-minimum-two-year-follow-up
#4
Sebastien Zilber, Eleonora Camana, Peter Lapner, Emil Haritinian, Laurent Nove Josserand
PURPOSE: Glenoid loosening is a common cause of reverse total shoulder arthroplasty (RTSA) failure, and grafting of the glenoid is often required for revision due to bone loss due to the central peg in most glenoid baseplates. Helical blades have been used in the hip to optimize bone fixation in proximal femoral fracture. This study presents the initial results of specifically designed helical blade in the shoulder to optimize glenoid bone fixation and preservation as part of RTSA. METHODS: Thirty-five patients underwent RTSA with glenoid helical blade fixation...
March 26, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29574819/implant-based-rehabilitation-options-for-the-atrophic-edentulous-jaw
#5
K R Spencer
The atrophic and edentulous jaw can pose a number of challenges for the implant clinician. In simple terms, the amount of bone that remains is insufficient for the conventional placement of a dental implant. A variety of treatment strategies can be employed to enable implants to be placed despite the paucity of bone stock in either the mandible or the maxilla. Conceptually these strategies follow one of two pathways: either augmentation of the bone, or the novel utilization of the remaining bone. This article will discuss patient assessment, treatment planning, and the range of contemporary options available to enable fixed implant based rehabilitation of each jaw...
March 2018: Australian Dental Journal
https://www.readbyqxmd.com/read/29569139/bone-preserving-total-hip-arthroplasty-in-avascular-necrosis-of-the-hip-a-matched-pairs-analysis
#6
David Merschin, Richard Häne, Mersedeh Tohidnezhad, Thomas Pufe, Wolf Drescher
PURPOSE: Short-stem hip arthroplasty has the potential advantage of femoral bone stock preservation, especially in view of the expected revisions in the often relatively young patients. Despite short-stem hip prosthesis are increasingly used for total hip arthroplasty, there are no sufficient mid- and long-term results especially for patients with avascular femoral head osteonecrosis. The present study investigates mid-term functional results as well as the revision rate following implantation of a short-stem prosthesis...
March 22, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29564298/pauwels-osteotomy-for-femoral-neck-nonunion-in-two-adult-siblings-with-osteogenesis-imperfecta
#7
Peter Kloen, Johanna C E Donders, E Marelise W Eekhoff, Reggie C Hamdy
This is a retrospective review of two adult siblings with osteogenesis imperfecta (OI) type III (according to Sillence classification), who sustained a spontaneous femoral neck fracture and subsequent nonunion. The diagnosis of OI in these two patients was made based on clinical, radiological and genetic findings. The fracture was most likely caused by femoroacetabular impingement secondary to OI induced acetabular protrusio. A valgus osteotomy according to Pauwels'principles and fixation of the osteotomy and nonunion with a locking plate resulted in healing despite compromised bone quality and limited bone stock...
March 2018: Hip & Pelvis
https://www.readbyqxmd.com/read/29554149/a-mouse-model-for-evaluation-of-efficacy-and-concomitant-toxicity-of-anti-human-cxcr4-therapeutics
#8
Maria José Costa, Jyothirmayee Kudaravalli, Wen-Hui Liu, Jeffrey Stock, Sophanna Kong, Shu-Hui Liu
The development of therapeutic monoclonal antibodies through mouse immunization often originates drug candidates that are not cross-reactive to the mouse ortholog. In such cases, and particularly in oncology, drug efficacy studies are performed on human tumor xenografts or with "surrogate" anti-mouse ortholog antibodies if targeting tumor host cells. Safety assessment of drug candidate(s) is performed at a later development stage in healthy non-human primates. While the latter remains necessary before a drug advances into human subjects, it precludes evaluation of safety in disease conditions and drug de-risking during early development...
2018: PloS One
https://www.readbyqxmd.com/read/29526560/biomechanical-simulation-of-temporomandibular-joint-replacement-tmjr-devices-a-scoping-review-of-the-finite-element-method
#9
REVIEW
Y L Rodrigues, M T Mathew, L G Mercuri, J S P da Silva, B Henriques, J C M Souza
The aim of this study was to perform a literature review on the use of finite element modeling (FEM) for the evaluation of the biomechanical behavior of temporomandibular joint replacement (TMJR) devices. An electronic search of online medical and scientific literature database was conducted using selected search terms. The search identified 307 studies, of which 19 were considered relevant to this study. Of the 19 selected studies, 10 (52.6%) investigated the influence of geometry and fixation methods, while two (10...
March 8, 2018: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29519425/strontium-modification-of-porous-scaffolds-from-mineralized-collagen-for-potential-use-in-bone-defect-therapy
#10
Mandy Quade, Matthias Schumacher, Anne Bernhardt, Anja Lode, Marian Kampschulte, Andrea Voß, Paul Simon, Ortrud Uckermann, Matthias Kirsch, Michael Gelinsky
The present study describes the development and characterization of strontium(II)-modified biomimetic scaffolds based on mineralized collagen type I as potential biomaterial for the local treatment of defects in systemically impaired (e.g. osteoporotic) bone. In contrast to already described collagen/hydroxyapatite nanocomposites calcium was substituted with strontium to the extent of 25, 50, 75 and 100mol% by substituting the CaCl2 -stock solution (0.1M) with SrCl2 (0.1M) during the scaffold synthesis. Simultaneous fibrillation and mineralization of collagen led to the formation of collagen-mineral nanocomposites with mineral phases shifting from nanocrystalline hydroxyapatite (Sr0) over poorly crystalline Sr-rich phases towards a mixed mineral phase (Sr100), consisting of an amorphous strontium phosphate (identified as Collin's salt, Sr6 H3 (PO4 )5 ∗2 H2 O, CS) and highly crystalline strontium hydroxyapatite (Sr5 (PO4 )3 OH, SrHA)...
March 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29516162/replacement-options-for-the-b2-glenoid-in-osteoarthritis-of-the-shoulder-a-biomechanical-study
#11
Boris Sowa, Martin Bochenek, Steffen Braun, Felix Zeifang, Jan Philippe Kretzer, Thomas Bruckner, Gilles Walch, Patric Raiss
BACKGROUND: Glenoid replacement in cases of severe glenoid retroversion (RV) or eccentric wear is challenging. The aim of this study was to evaluate different treatment methods under standardized conditions to assist surgeons in the decision-making process. METHODS: Three treatment options for severe glenoid RV (15°) were compared: (1) no RV correction; (2) complete RV correction; (3) no RV correction and implantation of a posterior augmented glenoid (PAG). A highly standardized implantation protocol using artificial glenoid bones (five per group) was chosen, and a physiologic shoulder movement was applied in a biomechanical setting...
March 7, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29511673/structural-and-morselized-allografting-combined-with-a-cementless-cup-for-acetabular-defects-in-revision-total-hip-arthroplasty-a-4-to-14-year-follow-up
#12
Hou-Tsung Chen, Cheng-Ta Wu, Tsan-Wen Huang, Hsin-Nung Shih, Jun-Wen Wang, Mel S Lee
Using morselized and structural allograft to restore bone stock for massive acetabular bone defect in revision total hip arthroplasty (THA) is an appealing procedure. However, concerns about inability to achieve long-term stability following allograft resorption remained. From 2003 to 2012, 59 hips in 58 patients undergoing revision THA for Paprosky type II or III acetabular defects were retrospectively reviewed. The acetabular defects were managed with deep-frozen morselized and structural allografts, and a press-fit cementless cup along with supplementary screws...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29510951/treatment-of-high-grade-acetabular-defects-do-porous-titanium-cups-provide-better-stability-than-traditional-titanium-cups-when-combined-with-an-augment
#13
Nicholas A Beckmann, Rudi G Bitsch, Maciej B Janoszka, Matthias C Klotz, Thomas Bruckner, Sebastian Jaeger
BACKGROUND: Revision total hip arthroplasty frequently faces challenges associated with deficient bone stock. Porous metal implants were developed to meet the challenge, but require rapid osseointegration for ultimate success. This study aims to assess relative motion as an indicator for primary stability and osseointegration of two different titanium cups each combined with a titanium augment. METHODS: In 14 cadaver hemipelvises, 2 types of titanium acetabular cups, a traditional sintered-bead cup (POROCOAT Acetabular Cup [PAC]) and a newer porous-coated cup (GRIPTION Acetabular Cup [GAC]) each associated with a porous augment, were subjected to 3-dimensional varying loads, replicating 30% of loads experienced during normal gait...
February 5, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29477178/inner-tooth-morphology-of-homo-erectus-from-zhoukoudian-new-evidence-from-an-old-collection-housed-at-uppsala-university-sweden
#14
Clément Zanolli, Lei Pan, Jean Dumoncel, Ottmar Kullmer, Martin Kundrát, Wu Liu, Roberto Macchiarelli, Lucia Mancini, Friedemann Schrenk, Claudio Tuniz
Locality 1, in the Lower Cave of the Zhoukoudian cave complex, China, is one of the most important Middle Pleistocene paleoanthropological and archaeological sites worldwide, with the remains of c. 45 Homo erectus individuals, 98 mammalian taxa, and thousands of lithic tools recovered. Most of the material collected before World War II was lost. However, besides two postcranial elements rediscovered in China in 1951, four human permanent teeth from the 'Dragon Bone Hill,' collected by O. Zdansky between 1921 and 1923, were at the time brought to the Paleontological Institute of Uppsala University, Sweden, where they are still stored...
March 2018: Journal of Human Evolution
https://www.readbyqxmd.com/read/29474948/assessment-of-a-press-fit-proximal-femoral-modular-reconstruction-implant-pfmr%C3%A2-at-14-5-years-a-48-case-series-with-a-disturbing-rate-of-implant-fracture
#15
Q Dumoulin, S Sabau, T Goetzmann, A Jacquot, F Sirveaux, D Mole, O Roche
INTRODUCTION: The PFMR® proximal femoral modular reconstruction implant (Protek, Sulzer Orthopedics, Switzerland) is a straight modular stem in sanded titanium with press-fit anchorage, intended to achieve spontaneous bone reconstruction following Wagner's principle. The aim of the present study was to analyze long-term clinical and radiological outcome. MATERIAL AND METHOD: A single-center retrospective study included 48 PFMR stems implanted in 47 patients between 1998 and 2002...
February 20, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29464283/-osteoarthritis-of-the-shoulder-pathogenesis-diagnostics-and-conservative-treatment-options
#16
REVIEW
J Mehl, A B Imhoff, K Beitzel
PATHOGENESIS: Osteoarthritis of the shoulder is characterized by a progressive degenerative process, which is based on chronic inflammation with intra-articular release of different cytokines and proteolytic enzymes. The main predisposing factors are a history of trauma or surgery, as well as chronic overuse or instability of the glenohumeral joint. Affected patients especially suffer from impaired joint function and pain, which are often associated with cognitive and psychosocial restrictions...
February 20, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29455347/a-prospective-comparative-study-of-hip-resurfacing-arthroplasty-and-large-diameter-head-metal-on-metal-total-hip-arthroplasty-in-younger-patients-a-minimum-of-five-year-follow-up
#17
Ran Tao, Fan Liu, Ya-Ke Liu, Yue Lu, Hua Xu, Yi Cao, Zhen-Yu Zhou, Wei Wang
INTRODUCTION: Both hip resurfacing arthroplasty (HRA) and large-diameter head metal-on-metal total hip arthroplasty (LDH MoM THA) are generally used for young and active patients. A number of comparative studies of HRA and total hip arthroplasty have been published in the literature. However, studies that have compared HRA with LDH MoM THA are rare. The purpose of this study is to compare the mid-term results of HRA with those of LDH MoM THA in young patients. PATIENTS AND METHODS: Between 2007 and 2011, 68 patients were enrolled in the study and randomized into two groups: HRA group (28 hips) and LDH MoM THA group (40 hips)...
February 18, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29440390/high-dietary-fat-and-sucrose-results-in-an-extensive-and-time-dependent-deterioration-in-health-of-multiple-physiological-systems-in-mice
#18
James G Burchfield, Melkam A Kebede, Christopher C Meoli, Jacqueline Stöckli, P Tess Whitworth, Amanda L Wright, Nolan J Hoffman, Annabel Y Minard, Xiuquan Ma, James R Krycer, Marin E Nelson, Shi-Xiong Tan, Belinda Yau, Kristen C Thomas, Natalie K Y Wee, Ee-Cheng Khor, Ronaldo F Enriquez, Bryce Vissel, Trevor J Biden, Paul A Baldock, Kyle L Hoehn, James Cantley, Gregory J Cooney, David E James, Daniel J Fazakerley
Obesity is associated with metabolic dysfunction, including insulin resistance and hyperinsulinemia, and with disorders such as cardiovascular disease, osteoporosis, and neurodegeneration. Typically, these pathologies are examined in discrete model systems and with limited temporal resolution, and whether these disorders co-occur is therefore unclear. To address this question, here we examined multiple physiological systems in male C57BL/6J mice following prolonged exposure to a high-fat/high-sucrose diet (HFHSD)...
April 13, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29430399/associated-reconstruction-of-anterior-cruciate-and-anterolateral-ligaments-with-single-asymmetric-hamstring-tendons-graft
#19
Alejandro Espejo-Baena, Alejandro Espejo-Reina, Abel Gómez-Cáceres, Maria Josefa Espejo-Reina, Jaime Dalla Rosa-Nogales
The anterior cruciate ligament (ACL) rupture is a common disease that accounts for 250,000 cases/year in the United States. The anterolateral ligament (ALL) has been suggested to be an important restraint for rotational instability, and its reconstruction provides a reinforcement to the ACL reconstruction in this aspect, especially in high-demand athletes and in knees with high-grade pivot shift. Different techniques for associated ACL and ALL reconstruction have been described, but the ideal technique remains unclear...
October 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29425756/management-of-bilateral-edentulous-mandible-fractures-through-an-intraoral-approach-using-cad-cam-technology-a-case-report
#20
Howard D Wang, Christopher Frost, Alessandro Cusano, Amir H Dorafshar
The surgical management of edentulous mandible fractures presents unique challenges secondary to poor bone stock and the absence of dentition to assist with fracture reduction. In complex injury patterns, such as bilateral edentulous mandible fractures, an external approach is often necessary to achieve adequate reduction and adaptation of a load-bearing reconstruction plate. We report a case in which computer-assisted design/computer-assisted manufacturing (CAD/CAM) was applied as an adjunct for the acute management of bilateral edentulous mandible fractures in a 58-year-old man...
January 31, 2018: Journal of Oral and Maxillofacial Surgery
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