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https://www.readbyqxmd.com/read/28802414/management-of-resistant-distal-femur-non-unions-with-allograft-strut-and-autografts-combined-with-osteosynthesis-in-a-series-of-22-patients
#1
Raja Bhaskara Kanakeshwar, Dheenadhayalan Jayaramaraju, Devendra Agraharam, Shanmuganathan Rajasekaran
INTRODUCTION AND PURPOSE: Challenges to the surgeon in managing cases of resistant non-union of the distal femur include poor bone stock, disuse osteopenia and joint contractures. Procedures varying from simple bone grafting to megaprosthesis revision have been described. We successfully managed such cases using our technique of combining cortical allograft struts to augment the defect in the femoral condyle coupled with autogenous iliac crest bone grafting and locking plate osteosynthesis...
August 2017: Injury
https://www.readbyqxmd.com/read/28795210/-arthrodesis-of-the-trapeziometacarpal-joint
#2
REVIEW
T Pillukat, M Mühldorfer-Fodor, R Fuhrmann, J Windolf, J van Schoonhoven
OBJECTIVE: Bony fusion of the trapeziometacarpal joint. INDICATIONS: High demands concerning stability and strength of the thumb in primary or secondary osteoarthritis (e.g., posttraumatic osteoarthritis following injuries to the carpometacarpal joint of the thumb); instability in the absence of osteoarthritis due to malformations, ligamentous laxicity, and joint hypermobility; malformations; improvement of hand function in neurological disorders; salvage procedure after carpometacarpal arthroplasty provided bone stock is sufficient...
August 9, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28790471/should-total-hip-arthroplasty-be-performed-acutely-in-the-treatment-of-acetabular-fractures-in-elderly-or-used-as-a-salvage-procedure-only
#3
Katharine Hamlin, Gabija Lazaraviciute, Michalis Koullouros, Tarak Chouari, Iain M Stevenson, Steven W Hamilton
BACKGROUND: Total hip arthroplasty (THA) is now an increasingly common procedure for people sustaining acetabular fractures. The incidence of acetabular fractures among the elderly population is increasing, and contemporary treatment aims to avoid the risks of prolonged incumbency associated with poor bone stock for fixation or inability to comply with limited weightbearing in this patient group. The concept of acute hip arthroplasty as a treatment for acetabular fracture is, therefore, becoming more topical and relevant...
July 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28790467/current-concepts-in-acetabular-positioning-in-total-hip-arthroplasty
#4
Deepu Bhaskar, Asim Rajpura, Tim Board
Being one of the most successful surgeries in the history of medicine, the indications for total hip arthroplasty have widened and are increasingly being offered to younger and fitter patients. This has also led to high expectations for longevity and outcomes. Acetabular cup position has a significant impact on the results of hip arthroplasty as it affects dislocation, abductor muscle strength, gait, limb lengths, impingement, noise generation, range of motion (ROM), wear, loosening, and cup failure. The variables in cup position are depth, height, and angular position (anteversion and inclination)...
July 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28750857/interventions-for-improving-hip-resurfacing-outcomes-in-women-a-high-volume-retrospective-study
#5
Emily B Gaillard, Melissa D Gaillard, Thomas P Gross
BACKGROUND: Women seeking surgical intervention for their hip disorders will often find total hip arthroplasty (THA) presented as their only option. THA, when compared with hip resurfacing arthroplasty, removes substantially more bone-stock, limits range-of-motion, exhibits increased dislocation risk, and presents greater overall 10-year mortality rate. Despite these risks, most surgeons continue to select against women for hip resurfacing because registries notoriously report inferior survivorship when compared with men and THA...
June 9, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28747983/comparision-of-doxorubicin-induced-cardiotoxicity-in-the-icr-mice-of-different-sources
#6
Sou Hyun Kim, Keuk-Jun Kim, Joung-Hee Kim, Jae-Hwan Kwak, HyunKeun Song, Joon Young Cho, Dae Youn Hwang, Kil Soo Kim, Young-Suk Jung
Doxorubicin is a widely used chemotherapeutic agents and is now part of standard therapeutic regimens for a variety of cancers (eg, hematopoietic malignancies and advanced solid tumors of the breast, ovary, thyroid, and bone). However, a potentially lethal and dose-dependent cardiotoxicity that appears within a short time after treatment limits the usage of doxorubicin in cancer patients. Although the mechanism of doxorubicin-induced cardiotoxicity is not completely understood, it is thought that free radical-induced oxidative stress and excessive production of reactive oxygen species are primary drivers of its toxicity...
June 2017: Laboratory Animal Research
https://www.readbyqxmd.com/read/28735842/angled-bio-rsa-bony-increased-offset-reverse-shoulder-arthroplasty-a-solution-for-the-management-glenoid-bone-loss-and-erosion
#7
Pascal Boileau, Nicolas Morin-Salvo, Marc-Olivier Gauci, Brian L Seeto, Peter N Chalmers, Nicolas Holzer, Gilles Walch
BACKGROUND: Glenoid deficiency and erosion (excessive retroversion/inclination) must be corrected in reverse shoulder arthroplasty (RSA) to avoid prosthetic notching or instability and to maximize function, range of motion, and prosthesis longevity. This study reports the results of RSA with an angled, autologous glenoid graft harvested from the humerus (angled BIO-RSA). METHODS: A trapezoidal bone graft, harvested from the humerus and fixed with a long-post baseplate and screws, was used to compensate for residual glenoid bone loss/erosion...
July 20, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28716179/surgical-treatment-of-chronic-rhinosinusitis-after-sinus-lift
#8
Nicole Tin-Lok Jiam, Andrew N Goldberg, Andrew H Murr, Steven D Pletcher
BACKGROUND: The sinus lift (or sinus augmentation) is a common procedure to improve maxillary bone stock before dental implantation. Chronic rhinosinusitis (CRS) is a potential complication of this procedure and may be refractory to medical treatment. Functional endoscopic sinus surgery has previously been used to address CRS, however, results of previous studies indicated that implant removal is required. There are limited follow-up data available. OBJECTIVE: The purpose of this study was to characterize the long-term outcomes and efficacy of endoscopic sinus surgery for refractory CRS after sinus lift, including the ability to salvage dental implants...
July 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28716026/short-stem-total-hip-arthroplasty-for-osteonecrosis-of-the-femoral-head-in-patients-60%C3%A2-years-or-younger-a-3-to-10-year-follow-up-study
#9
Antonio Capone, Fabrizio Bienati, Stefania Torchia, Daniele Podda, Giuseppe Marongiu
BACKGROUND: In young patients with osteonecrosis of the femoral head (ONFH), short-stem total hip arthroplasty (THA) could allow a potential advantage in preserving metaphyseal bone-stock, when revision surgery might become necessary. However, only a few studies have evaluated the outcome of short-stem THAs in ONFH. We reviewed the prospectively collected data of a cementless partial neck-retaining short-stem with ceramic-on-ceramic bearings in ONFH patients. METHODS: Thirty patients (37 hips) younger than 60 years (mean age at surgery, 51...
July 17, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28689825/biomechanical-analysis-of-anterior-bone-graft-augmentation-with-reversed-shoulder-arthroplasty-in-large-combined-glenoid-defects-compared-with-total-bony-joint-line-reconstruction-modified-bony-increased-offset-reversed-shoulder-arthroplasty
#10
Matthias Königshausen, Nina Sverdlova, Corinna Mersmann, Christoph Ehlert, Birger Jettkant, Rolf Dermietzel, Thomas Armin Schildhauer, Dominik Seybold
BACKGROUND: The aim of this biomechanical study was to compare 2 surgical techniques for the reconstruction of large, combined, uncontained glenoid defects with reversed shoulder arthroplasty (RSA). METHODS: Three groups of scapulae with RSA were tested by the application of a physiological combination of compressive/shear loads in Sawbones (Pacific Research Laboratories, Inc., Vashon Island, WA, USA) and cadavers. Two of the groups (both Sawbones and cadaveric specimens) consisted of anterior combined defects (14 mm in depth), and the third group served as a control group (only Sawbones specimens)...
July 6, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28683980/midterm-survivorship-and-complications-of-total-knee-arthroplasty-in-patients-with-dwarfism
#11
Timothy L Tan, Michael M Kheir, Ronuk Modi, Chi-Lung Chen, Hongyi Shao, Antonia F Chen
BACKGROUND: Dwarfism is associated with skeletal dysplasias and joint deformities that frequently result in osteoarthritis requiring treatment with total knee arthroplasty (TKA). These surgeries can be challenging because of alignment deformities, poor bone stock, and smaller components. This study aims to compare TKA implant survivorship and complications between dwarf and nondwarf patients. METHODS: A retrospective case-control study was performed from 1997-2014 evaluating 115 TKAs in patients under the height threshold of 147...
June 9, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28669018/revision-knee-arthroplasty-using-a-distal-femoral-replacement-prosthesis-for-periprosthetic-fractures-in-elderly-patients
#12
Ehab Girgis, Christoph McAllen, Jonathan Keenan
PURPOSE: Distal femoral periprosthetic fractures above a total knee replacement in elderly patients are technically challenging to treat. Bone quality is often poor, the fractures comminuted, and post-operative mobilisation is difficult. This study assesses the clinical, radiological and functional outcome of revision knee distal femoral replacement (DFR) in these fractures. METHODS: We identified 14 patients over 70 years of age (70-94) who underwent DFR for periprosthetic fractures above a knee replacement...
July 1, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28662954/structural-allograft-supporting-a-trabecular-metal-cup-provides-durable-results-in-complex-revision-arthroplasty
#13
Hernan A Prieto, Michael E Kralovec, Daniel J Berry, Robert T Trousdale, Rafael J Sierra, Miguel E Cabanela
BACKGROUND: Revision total hip arthroplasty (THA) is challenging specially in the presence of severe acetabular bone deficiency. We report the use of a highly porous revision shell augmented by structural allograft to provide structural support and coverage to the acetabular component. METHODS: We identified 56 patients (58 hips) undergoing revision THA, where a trabecular metal revision cup was supported by structural allograft. Mean follow-up was 5.4 years (range 2-12 years)...
June 8, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28650443/sulfated-glycopeptide-nanostructures-for-multipotent-protein-activation
#14
Sungsoo S Lee, Timmy Fyrner, Feng Chen, Zaida Álvarez, Eduard Sleep, Danielle S Chun, Joseph A Weiner, Ralph W Cook, Ryan D Freshman, Michael S Schallmo, Karina M Katchko, Andrew D Schneider, Justin T Smith, Chawon Yun, Gurmit Singh, Sohaib Z Hashmi, Mark T McClendon, Zhilin Yu, Stuart R Stock, Wellington K Hsu, Erin L Hsu, Samuel I Stupp
Biological systems have evolved to utilize numerous proteins with capacity to bind polysaccharides for the purpose of optimizing their function. A well-known subset of these proteins with binding domains for the highly diverse sulfated polysaccharides are important growth factors involved in biological development and tissue repair. We report here on supramolecular sulfated glycopeptide nanostructures, which display a trisulfated monosaccharide on their surfaces and bind five critical proteins with different polysaccharide-binding domains...
August 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/28622117/periprosthetic-femoral-fractures-in-the-emergency-department-what-the-orthopedic-surgeon-wants-to-know
#15
Richard A Marshall, Michael J Weaver, Aaron Sodickson, Bharti Khurana
Femoral fracture in the setting of a hip arthroplasty is an increasingly common complication encountered in the emergency department (ED). Diagnosis and management of periprosthetic fractures are complicated, and orthopedic surgeons rely on imaging findings to guide the appropriate management approach to the injury. Delay in identification and appropriate definitive management of periprosthetic fractures is associated with high morbidity and mortality. At present, the Vancouver classification system for periprosthetic hip fractures is the most common classification system used by orthopedic surgeons...
July 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28617737/3d-cone-beam-computed-tomography-volumetric-outcomes-of-rhbmp-2-demineralized-bone-matrix-vs-iliac-crest-bone-graft-for-alveolar-cleft-reconstruction
#16
Fan Liang, Stephen Yen, Thomas Imahiyerobo, Luke Sanborn, Leia Yen, Daniel Yen, Sheila Nazarian, Breanna Jedrzejewski, Mark Urata, Jeffrey Hammoudeh
BACKGROUND: Recent studies indicate that recombinant human bone morphogenetic protein (rhBMP-2) in a demineralized bone matrix scaffold (MS) is a comparable alternative to iliac bone autograft in the setting of secondary alveolar cleft repair. Post-reconstruction occlusal radiographs demonstrate improved bone stock when rhBMP-2/MS is used, but lack the capacity to evaluate bone growth in three dimensions. This study uses cone beam computed tomography (CBCT) to provide the first clinical evaluation of volumetric and density comparisons between these two treatment modalities...
June 14, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28595799/revision-total-hip-arthroplasty-salvage-procedures-using-bone-allografts-in-japan
#17
Katsufumi Uchiyama, Gen Inoue, Naonobu Takahira, Masashi Takaso
Total hip arthroplasty (THA) and hemiarthroplasty have improved hip joint function of patients suffering from hip disease or trauma with excellent clinical results and long-term survivorship. Conversely, there has been an increase in the number of revision surgeries after THA and hemiarthroplasty due to bone deficiency. The reconstruction of deficient bone remains a challenging problem following THA. While performing revision surgery, we have previously classified the preoperative bone deficiency using X-ray, CT and three-dimensional CT imaging according to location and severity of the deficiencies...
June 5, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28594498/bicompartmental-knee-arthroplasty
#18
Nirav H Amin, Travis Scudday, Fred D Cushner
Knee arthritis is one of the leading causes of disability and functional limitations in the United States and worldwide. Total knee arthroplasty results in good functional outcomes and high survival rates in patients who have tricompartmental arthritis. Bicompartmental knee arthroplasty is being used more often in patients who have arthritis that is isolated to two compartments: the patellofemoral compartment and either the medial or the lateral compartment. Bicompartmental knee arthroplasty preserves the kinematics, ligaments, and bone stock of the knee and is a good option for younger, active, high-demand patients who wish to return to their previous level of activity...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28594312/warning-about-the-use-of-critical-size-defects-for-the-translational-study-of-bone-repair-analysis-of-a-sheep-tibial-model
#19
Johan Lammens, Marina Maréchal, Lisbet Geris, Joshua Van der Aa, Hadewych Van Hauwermeiren, Frank P Luyten, Hendrik Delport
The repair of large long bone defects requires complex surgical procedures as the bone loss cannot simply be replaced by autologous grafts due to an insufficient bone stock of the human body. Tissue engineering strategies and the use of Advanced Therapy Medicinal Products (ATMPs) for these reconstructions remain a considerable challenge, in particular since robust outcomes in well-defined large animal models are lacking. To be suitable as a model for treatment of human sized bone defects, we developed a large animal model in both skeletally immature and mature sheep and made close observations on the spontaneous healing of defects...
July 3, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28593199/analysis-of-instrumentation-failures-after-three-column-osteotomies-of-the-spine
#20
Niranjan Kavadi, Richard A Tallarico, William F Lavelle
BACKGROUND: Correction of fixed spinal imbalance in a sagittal and/or coronal plane frequently needs a tricolumnar wedge resection when the deformity is rigid. Complications associated with deformity correction surgery are pseudoarthrosis and implant failure located along the construct. The purposes of this study were to assess comparative rates of pseudoarthrosis (implant failure) at weaker points along lumbosacral junction and level of osteotomy, estimate overall incidence of implant failure, and comparatively analyze failures at different points along the construct...
2017: Scoliosis and Spinal Disorders
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