Read by QxMD icon Read

dengue review pediatrics

Sriram Pothapregada, Banupriya Kamalakannan, Mahalaskhmy Thulasingham, Srinivasan Sampath
OBJECTIVE: To study the clinical profile and outcome of dengue fever in children at a tertiary care hospital in Puducherry. MATERIALS AND METHODS: All children (0-12 years of age) diagnosed and confirmed as dengue fever from August 2012 to January 2015 were reviewed retrospectively from hospital case records as per the revised World Health Organization guidelines for dengue fever. The diagnosis was confirmed by NS1 antigen-based ELISA test or dengue serology for IgM and IgG antibodies, and the data were analyzed using SPSS 16...
July 2016: Journal of Global Infectious Diseases
Junxiong Pang, Yee-Sin Leo, David C Lye
PURPOSE OF REVIEW: This review aims to update and summarize the current knowledge about clinical features, management, and risk factors of adult dengue patients requiring intensive care with consequently higher risk of mortality. RECENT FINDINGS: Increasingly, there are more adult dengue patients who require intensive care. This may be due to a shift in epidemiology of dengue infection from mainly a pediatric disease toward adult disease. In addition, multiorgan dysfunction was observed to be a key risk factor for ICU admission and mortality...
October 2016: Current Opinion in Critical Care
George S Han, Christopher J Gregory, Brad J Biggerstaff, Kalanthe Horiuchi, Carmen Perez-Guerra, Eunice Soto-Gomez, Desiree Matos, Harold S Margolis, Kay M Tomashek
BACKGROUND:  Prior to 2010, the clinical management of dengue in Puerto Rico was inconsistent with World Health Organization guidelines. A 4-hour classroom-style course on dengue clinical management was developed in 2009 and mandated for Puerto Rico medical licensure in 2010. Fifty physicians were trained as "master trainers" and gave this course to 7638 physicians. This study evaluated the effect of the course on the clinical management of hospitalized dengue patients. METHODS:  Pre- and post-course test responses were compared...
August 8, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Pooja Hebbal, Yamil Darwich, Jane Fong, Stefan H F Hagmann, Murli U Purswani
We report a case of an eight-year-old male, native of the Dominican Republic, who visited the U.S. and was admitted to a pediatric intensive care unit with severe dengue. He needed aggressive fluid management for dengue shock syndrome and developed proteinuria on the sixth day of his illness, shortly after his nadir thrombocytopenia. His proteinuria peaked on the eight day, and reduced to trace levels by the tenth day of his illness, coinciding with normalization of his platelet count. His highest random urine protein/creatinine ratio was in the nephrotic range, at 3...
January 2016: Travel Medicine and Infectious Disease
Jacqueline Kyungah Lim, Yong-Seok Lee, Annelies Wilder-Smith, Georges Thiry, Richard Mahoney, In-Kyu Yoon
Dengue is a public health problem in the tropics and subtropics. There are several vaccine candidates in clinical development. However, there may be gaps in the new vaccine introduction after vaccine licensure before it becomes available in developing countries. In anticipation of the first dengue vaccine candidate to be licensed, Dengue Vaccine Initiative (DVI) and, its predecessor, Pediatric Dengue Vaccine Initiative (PDVI) have been working on points for consideration to accelerate evidence-based dengue vaccine introduction, once a vaccine becomes available...
2016: Expert Review of Vaccines
Daniela Nasu Monteiro Medeiros, Juliana Ferreira Ferranti, Artur Figueiredo Delgado, Werther Brunow de Carvalho
AIM: The goal of this study was to perform a systematic review of the literature assessing the use of colloids for the initial treatment of severe sepsis and septic shock in pediatric patients. DESIGN: The PICO [Patient, Intervention, Comparison, Outcome] method was used for the selection of studies, and the Cochrane Bias Tool was used to analyze the quality of the selected studies. DATA SEARCH: Relevant studies were sought using the following databases: EMBASE (1980 to March 2014), PubMed (1970 to March 2014), Cochrane (1980 to March 2014), Web of Science, and Scopus...
November 2015: Pediatric Emergency Care
Bette K Kleinschmidt-DeMasters, J David Beckham
Arboviruses (Arthropod-borne viruses) include several families of viruses (Flaviviridae, Togaviradae, Bunyaviradae, Reoviradae) that are spread by arthropod vectors, most commonly mosquitoes, ticks and sandflies. The RNA genome allows these viruses to rapidly adapt to ever-changing host and environmental conditions. Thus, these virus families are largely responsible for the recent expansion in geographic range of emerging viruses including West Nile virus (WNV), dengue virus and Chikungunya virus. This review will focus on WNV, especially as it has progressively spread westward in North America since its introduction in New York in 1999...
September 2015: Brain Pathology
Andre Rebaza, Paul J Lee
Increasing numbers of children are traveling to developing countries where they are often at a higher risk than adults of acquiring vaccine-preventable diseases. Yet, they are less likely to receive pretravel medical advice and preventive care. This article reviews the current recommendations for pediatric travel immunizations, including specific travel vaccines such as typhoid, yellow fever, Japanese encephalitis virus, and rabies as well as prospective vaccines for significant global diseases like malaria, dengue, chikungunya, and Ebola...
April 2015: Pediatric Annals
Alfredo J Mena Lora, Josefina Fernandez, Alfredo Morales, Yahaira Soto, Jesus Feris-Iglesias, Maximo O Brito
Millions are infected with dengue yearly. We evaluated the epidemiological and clinical characteristics of pediatric patients infected with dengue in the Dominican Republic. The applicability of World Health Organization (WHO) warning signs for predicting severe dengue and mortality was also studied. This study was a cross-sectional retrospective review of patients with a clinical diagnosis of dengue. Univariate and multivariate analyses were performed to evaluate characteristics associated with severity and mortality...
January 2014: American Journal of Tropical Medicine and Hygiene
Kusum Menon, Dayre McNally, Karen Choong, Margaret Sampson
OBJECTIVE: To systematically review randomized controlled trials (RCTs) of steroids conducted in children with fluid and/or vasoactive medication-dependent shock and evaluate and report on the quality and clinical and methodological heterogeneity of included trials. DATA SOURCES: MEDLINE (1946 to January Week 2, 2012), Embase (1947-January 20, 2012), Cochrane Central Register of Controlled Trials (through January 2012), and reference lists of retrieved publications...
June 2013: Pediatric Critical Care Medicine
Kai-Hu Yao
Natural disasters may lead to the outbreaks of infectious diseases because they increase the risk factors for infectious diseases. This paper reviews the risk factors for infectious diseases after natural disasters, especially earthquake, and the infectious diseases following disasters reported in recent years. The infectious diseases after earthquake include diarrhea, cholera, viral hepatitis, upper respiratory tract infection, tuberculosis, measles, leptospirosis, dengue fever, tetanus, and gas gangrene, as well as some rare infections...
June 2013: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Angela María Gutiérrez-Alvarez, Nicolas Medina Silva, María Catalina Vargas Bazurto, Sindy Montoya Osorio
Electronic database Medline, Embase, Cochrane Library and Lilacs were used to retrieve the clinical trials that will evaluate the various therapeutical options available for management of hemorrhagic dengue. Eight clinical studies were included. Supportive care and symptomatic treatment through hydration and aggressive fluid management, if hypotension develops in the course of disease, are the most important aids to improve survival. Treatment with corticosteroids such as methylprednisolone, hydrocortisone, carbazochorome sodium sulfonate (AC-17) and recombinant activated factor VII did not reduce mortality in children with hemorrhagic dengue...
September 2006: Revista Cubana de Medicina Tropical
Thanyanat Bunnag, Siripen Kalayanarooj
BACKGROUND: Dengue virus infection is an important mosquito-borne disease with the reported 40,000-100,000 cases per year in Thailand. Shock is one of the common presentations at the emergency room (ER) and dengue shock syndrome (DSS) is among the common causes of shock. Proper and timely management of DSS determines the outcomes and prognosis of DSS patients. OBJECTIVE: To find the prevalence of DSS at the ER and evaluate the medical management and risk factors associated with the outcome of DSS patients...
August 2011: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Sunil Bhat, Satya Prakash Yadav, Madasu Anjan, Veronique Dinand, Anupam Sachdeva
OBJECTIVE: To determine the safety and efficacy of off label usage of Recombinant activated factor VII (rFVIIa) in children with severe bleeding in non-hemophiliac children with diverse etiologies like leukemia, post hematopoietic stem cell transplantation, dengue shock syndrome and Glanzmann thrombasthenia. METHOD: Medical records of 16 non-hemophiliac children with 20 bleeding episodes where rFVIIa was administered only after failure of standard measures to control bleeding were retrospectively reviewed and data collected regarding patient demographics, diagnosis and location of bleeding...
August 2011: Indian Journal of Pediatrics
Alice D Ackerman, Sunit Singhi
OBJECTIVE: To review important articles in the field of infectious diseases that pertain to the care of children in pediatric critical care units, published subsequent to the fourth edition of the Rogers' Textbook of Pediatric Intensive Care. DATA SOURCES: The U.S. National Library of Medicine was searched for the terms: critical care, nosocomial, antimicrobial resistance, opportunistic infection, sepsis, central nervous system infections, encephalitis, meningitis-bacterial, meningitis-tuberculous, brain abscess, measles, dengue, hemorrhagic fever, human immunodeficiency virus infection (HIV), opportunistic infections, fungal infections, tetanus, diphtheria, botulism, toxic shock syndrome, and pediatrics...
January 2010: Pediatric Critical Care Medicine
P Gérardin
Dengue (Df) and Chikungunya fever (Cf) arbovirosis are booming in the world, because of the plasticity of their pathogens, mutant RNA viruses making the acquisition of sustainable herd immunity and vaccination difficult in humans, and the plasticity of their vectors, the female mosquitoes of the genus Aedes (Stegomya), capable of adapting to different environments. This review summarizes the viral life cycle and epidemiology of these arboviruses, pathogenesis and pediatric aspects of their clinical forms and the basic principles of their treatment and prevention...
January 2010: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Jose A Suaya, Donald S Shepard, João B Siqueira, Celina T Martelli, Lucy C S Lum, Lian Huat Tan, Sukhontha Kongsin, Sukhum Jiamton, Fàtima Garrido, Romeo Montoya, Blas Armien, Rekol Huy, Leticia Castillo, Mariana Caram, Binod K Sah, Rana Sughayyar, Karen R Tyo, Scott B Halstead
Despite the growing worldwide burden of dengue fever, the global economic impact of dengue illness is poorly documented. Using a common protocol, we present the first multicountry estimates of the direct and indirect costs of dengue cases in eight American and Asian countries. We conducted prospective studies of the cost of dengue in five countries in the Americas (Brazil, El Salvador, Guatemala, Panama, and Venezuela) and three countries in Asia (Cambodia, Malaysia, and Thailand). All studies followed the same core protocol with interviews and medical record reviews...
May 2009: American Journal of Tropical Medicine and Hygiene
Nasim A Khan, Esam I Azhar, Suzan El-Fiky, Hosam H Madani, Maha A Abuljadial, Ahmad M Ashshi, Abdulhafis M Turkistani, Esam A Hamouh
OBJECTIVE: To describe clinical profile of patients with dengue virus infection hospitalized at a single center during the first outbreak of dengue in Makkah, Saudi Arabia from April to July 2004. METHODS: Clinical information and laboratory abnormalities of patients with suspected dengue infection were collected by a standardized data collection sheet and review of medical records. Dengue virus infection was confirmed by a positive IgM capture ELISA or RT-PCR. RESULTS: Of the 160 clinically suspected patients, 91 were confirmed (64 by IgM ELISA, 14 by RT-PCR and 13 by both) to have dengue virus infection...
January 2008: Acta Tropica
Viroj Wiwanitkit
BACKGROUND: Dengue infection is a major vector-borne disease. The classical sings and symptoms of this infection include high fever, violent headache, chill and rash. However, there are a number of atypical forms of dengue infection including those presented with liver dysfunction. However, there are only a few reports concerning the liver dysfunction among the patients with dengue infections. METHODS: Here, the author presents a summative study on the liver dysfunction and its clinical correlation among Thai patients in the previous studies...
January 2007: Journal of Ayub Medical College, Abbottabad: JAMC
E Khan, J Siddiqui, S Shakoor, V Mehraj, B Jamil, R Hasan
This is the first report of the largest epidemic of dengue hemorrhagic fever (DHF) virus infection (2006) with IgM-confirmed cases from Karachi, Pakistan. Medical records of 172 IgM-positive patients were reviewed retrospectively for demographic, clinical and laboratory data. Patients were categorized into dengue fever (DF) and DHF according to the WHO severity grading scale. The mean+/-SD age of the patients was 25.9+/-12.8 years, 55.8% were males and the hemoconcentration was recorded in a small number of patients [10 (7...
November 2007: Transactions of the Royal Society of Tropical Medicine and Hygiene
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"