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https://www.readbyqxmd.com/read/29684907/efficiency-of-extraction-and-conversion-of-pseudoephedrine-to-methamphetamine-from-tamper-resistant-and-non-tamper-resistant-formulations
#1
Brandon Presley, Bob Bianchi, John Coleman, Fran Diamond, Gerry McNally
Clandestine chemists have demonstrated an ability to convert commercially available pseudoephedrine formulations to methamphetamine. Some of these formulations have properties that manufacturers claim limit or block the extraction of pseudoephedrine and its direct conversion to methamphetamine. In this study, 3 commercially available pseudoephedrine formulations were evaluated for ease of extraction and conversion to methamphetamine using a common chemistry technique called the one-pot method that is frequently employed by clandestine chemists...
April 16, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29684822/sexual-dysfunction-among-nigerian-women-with-epilepsy
#2
Luqman Ogunjimi, Joseph Yaria, Akintomiwa Makanjuola, Adesola Ogunniyi
OBJECTIVES: Sexual dysfunction (SD) has been shown to be more prevalent among females with epilepsy (FWE) when compared with controls. Identified risk factors for SD among FWE include depression, antiepileptic drug (AED) type, epileptic lateralization, and temporal lobe involvement. Despite a huge population of FWE in sub-Saharan Africa and by extension Nigeria, there are limited studies on the effect of AEDs and epilepsy on sexual function among FWE in the region. We therefore studied predictors and patterns of SD among Nigerian FWE...
April 20, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29684795/screening-for-postpartum-anxiety-a-quality-improvement-project-to-promote-the-screening-of-women-suffering-in-silence
#3
Sarah Toler, Susan Stapleton, Kim Kertsburg, Tiffany J Callahan, Marie Hastings-Tolsma
BACKGROUND: Postpartum anxiety is a mental health problem that has largely been ignored by maternity care providers despite an estimated incidence as high as 28.9%. Though postpartum anxiety may or may not be accompanied by depression, and while screening for postpartum depression has become more common place, postpartum anxiety is often not assessed or addressed. PURPOSE: The purpose of this pilot quality improvement project was to implement a screening, treatment and referral program for postpartum anxiety in the birth centre environment...
April 3, 2018: Midwifery
https://www.readbyqxmd.com/read/29684659/anxiety-sensitivity-and-suicide-risk-among-firefighters-a-test-of-the-depression-distress-amplification-model
#4
Ian H Stanley, Lia J Smith, Joseph W Boffa, Jana K Tran, N Brad Schmidt, Thomas E Joiner, Anka A Vujanovic
BACKGROUND: Firefighters represent an occupational group at increased suicide risk. How suicidality develops among firefighters is poorly understood. The depression-distress amplification model posits that the effects of depression symptoms on suicide risk will be intensified in the context of anxiety sensitivity (AS) cognitive concerns. The current study tested this model among firefighters. METHODS: Overall, 831 firefighters participated (mean [SD] age = 38...
April 7, 2018: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29684625/nanomechanics-and-ultrastructure-of-the-internal-mammary-artery-adventitia-in-patients-with-low-and-high-pulse-wave-velocity
#5
Zhuo Chang, Paolo Paoletti, Steve D Barrett, Ya Hua Chim, Eva Caamaño-Gutiérrez, Maria Lyck Hansen, Hans Christian Beck, Lars Melholt Rasmussen, Riaz Akhtar
The collagen-rich adventitia is the outermost arterial layer and plays an important biomechanical and physiological role in normal vessel function. While there has been a lot of effort to understand the role of the medial layer on arterial biomechanics, the adventitia has received less attention. In this study, we hypothesized that different ultrastructural and nanomechanical properties would be exhibited in the adventitia of the internal mammary artery (IMA) in patients with a low degree of arterial stiffening as compared to those with a high degree of arterial stiffening...
April 20, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29684537/genetic-imaging-study-with-tc-99m-trodat-1-spect-in-adolescents-with-adhd-using-oros-methylphenidate
#6
Aynur Pekcanlar Akay, Gamze Çapa Kaya, Samet Kose, Çiğdem Eresen Yazıcıoğlu, Handan Özek Erkuran, Sevay Alşen Güney, Kaya Oğuz, Duygu Keskin, Burak Baykara, Neslihan İnal Emiroğlu, Mine Şencan Eren, Sefa Kızıldağ, Türkan Ertay, Dua Özsoylu, Süha Miral, Hatice Durak, Ali Saffet Gönül, Luis Augusto Rohde
AIM: To examine theeffects on the brain of 2-month treatment withamethylphenidate extended-release formulation (OROS-MPH) using [Tc-99m ] TRODAT-1SPECT in a sample of treatment-naïve adolescents with Attention Deficit/Hyperactivity Disorder (ADHD). In addition, to assess whether risk alleles (homozygosity for 10-repeat allele at the DAT1 gene were associated with alterations in striatal DAT availability. METHODS: Twenty adolescents with ADHD underwent brain single-photon emission computed tomography (SPECT) scans with [Tc-99m ] TRODAT-1 at baseline and two months after starting OROS-MPH treatment with dosages up to 1 mg/kg/day...
April 20, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29684518/long-term-outcomes-after-encephaloduroarteriosynangiosis-in-adult-patients-with-moyamoya-disease-presenting-with-ischemia
#7
Xiang-Yang Bao, Yong Zhang, Qian-Nan Wang, Qian Zhang, Hui-Wang, Zheng-Shan Zhang, De-Sheng Li, Lian Duan
BACKGROUND: In adult Moyamoya disease(MMD), there remains controversy about the effectiveness of revascularization surgeries because randomized studies have not been performed to compare the efficacy of surgical techniques. OBJECT: There is an ongoing controversy regarding the most appropriate surgical treatment for adult patients with MMD. METHODS: Encephaloduroarteriosynangiosis (EDAS) was performed on 247 hemispheres in 145 patients. The clinical and demographic characteristics of patients were obtained via retrospective chart review...
April 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29684136/effects-of-a-group-mediated-exercise-and-dietary-intervention-in-the-treatment-of-prostate-cancer-patients-undergoing-androgen-deprivation-therapy-results-from-the-idea-p-trial
#8
Brian C Focht, Alexander R Lucas, Elizabeth Grainger, Christina Simpson, Ciaran M Fairman, Jennifer M Thomas-Ahner, Jackie Buell, J Paul Monk, Amir Mortazavi, Steven K Clinton
Background: Although androgen-deprivation therapy (ADT) is the foundation of treatment for prostate cancer, the physiological impacts of ADT result in functional decline and enhanced risk of chronic disease and metabolic syndrome. Purpose: The Individualized Diet and Exercise Adherence Pilot Trial (IDEA-P) is a single-blind, randomized, pilot trial comparing the effects of a group-mediated, cognitive-behavioral (GMCB) exercise and dietary intervention (EX+D) with those of a standard-of-care (SC) control during the treatment of prostate cancer patients undergoing ADT...
April 19, 2018: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/29683840/enhancing-hiv-pre-exposure-prophylaxis-practices-via-an-educational-intervention
#9
Rebecca Newman, Tasleem Katchi, Michael Karass, Melissa Gennarelli, Jason Goutis, Alina Kifayat, Shantanu Solanki, Srikanth Yandrapalli, Leanne Forman, Christopher Nabors
BACKGROUND: Pre-exposure prophylaxis (PrEP) for HIV involves using antiretroviral drugs to prevent individuals at high risk from acquiring HIV infection. Most practicing primary care providers believe PrEP to be safe and effective, but less than half have prescribed or referred for PrEP. Attitudes and prescribing patterns among house officers have not been well described previously. STUDY QUESTION: Can an educational intervention enhance HIV PrEP practices among internal medicine house officers? STUDY DESIGN: This study relied on a pretest/posttest design...
April 20, 2018: American Journal of Therapeutics
https://www.readbyqxmd.com/read/29682417/integrated-economic-and-environmental-analysis-of-agricultural-straw-reuse-in-edible-fungi-industry
#10
Wencong Lu, Shuao Yu, Yongxi Ma, Hairong Huang
Background: China currently faces severe environmental pollution caused by burning agricultural straw; thus, resource utilization of these straws has become an urgent policy and practical objective for the Chinese government. Methods: This study develops a bio-economic model, namely, "straw resource utilization for fungi in China (SRUFIC)," on the basis of a field survey of an edible fungi plant in Zhejiang, China, to investigate an integrated economic and environmental performance of straw reuse in fungi production...
2018: PeerJ
https://www.readbyqxmd.com/read/29682228/physical-activity-and-depression-in-older-adults-with-and-without-cognitive-impairment
#11
Kornanong Yuenyongchaiwat, Khajonsak Pongpanit, Somrudee Hanmanop
Low physical activity and depression may be related to cognitive impairment in the elderly. Objetive: To determine depression and physical activity (PA) among older adults with and without cognitive impairment. Methods: 156 older adults, both males and females, aged ≥60 years, were asked to complete the Thai Mini-Mental State Examination (Thai-MMSE), a global cognitive impairment screening tool. Seventy-eight older adults with cognitive impairment and 78 older adults without cognitive impairment were then separately administered two questionnaires (i...
January 2018: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29682147/acupuncture-or-acupressure-on-yintang-ex-hn-3-for-anxiety-a-preliminary-review
#12
REVIEW
Chan-Young Kwon, Boram Lee
Background: Anxiety is a very common psychiatric symptom and can also occur in many physical conditions. Due to the limitations of conventional pharmacotherapy, the discovery of nonpharmacologic treatments that alleviate anxiety effectively is clinically important. Yintang (EX-HN 3), an acupoint located between the eyebrows, is known to have a mentally stabilizing effect in Traditional Chinese Medicine. Objectives: This preliminary review was conducted to investigate the current state of studies using acupressure or acupuncture on EX-HN 3 alone for anxiety, and to explore ways to apply this in clinical settings and future research, including systematic reviews and clinical trials...
April 1, 2018: Medical Acupuncture
https://www.readbyqxmd.com/read/29682017/the-organisms-and-factors-affecting-outcomes-of-external-ventricular-drainage-catheter-related-ventriculitis-a-penang-experience
#13
Jo Ee Sam, Chee Loon Lim, Priya Sharda, Nasser Abdul Wahab
Introduction: Ventriculostomy-related infection (VRI) from external ventricular drain (EVD) insertion is a common complication and carries a high mortality rate. Choice of empiric antibiotics depends on the institutions common causative organisms and their susceptibility. We determined risk factors for mortality in patients with VRI, the common organisms causing VRI, and the rate of EVD-related VRI at our institution. Methods: Medical records and operative data of patients with cerebrospinal fluid positive cultures with an EVD inserted from 2012 to 2015 were traced...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29682010/craniofacial-trauma-in-pediatric-patients-following-winnowing-blade-injury-review-of-literature
#14
REVIEW
Harsha Huliyappa, Balakrishna Ojha, Anil Chandra, Sunil Kumar Singh, Chhitij Srivastava
In developing countries, during the harvest season, winnower blade injuries occur very frequently in children and results in lifelong disability. Nine children were managed during 1 month, all resulting due to winnower blade induced craniofacial trauma. PubMed search for "fan blade injury" showed two case series and three case reports. In our study, 88% had compound depressed fracture; brain matter leak in 56%, cerebrospinal fluid (CSF) leak alone in 22%. 66.7% had injury involving the frontal bone...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29681884/glutathione-s-transferase-alpha-4-prevents-dopamine-neurodegeneration-in-a-rat-alpha-synuclein-model-of-parkinson-s-disease
#15
Michael Jewett, Elna Dickson, Kajsa Brolin, Matilde Negrini, Itzia Jimenez-Ferrer, Maria Swanberg
Parkinson's disease (PD) is a common, progressive neurodegenerative disease, which typically presents itself with a range of motor symptoms, like resting tremor, bradykinesia, and rigidity, but also non-motor symptoms such as fatigue, constipation, and sleep disturbance. Neuropathologically, PD is characterized by loss of dopaminergic cells in the substantia nigra pars compacta (SNpc) and Lewy bodies, neuronal inclusions containing α-synuclein (α-syn). Mutations and copy number variations of SNCA , the gene encoding α-syn, are linked to familial PD and common SNCA gene variants are associated to idiopathic PD...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29681646/full-scale-drinking-water-system-decontamination-at-the-water-security-test-bed
#16
Jeffrey Szabo, John Hall, Steve Reese, Jim Goodrich, Sri Panguluri, Greg Meiners, Hiba Ernst
The EPA's Water Security Test Bed (WSTB) facility is a full-scale representation of a drinking water distribution system. In collaboration with the Idaho National Laboratory (INL), EPA designed the WSTB facility to support full-scale evaluations of water infrastructure decontamination, real-time sensors, mobile water treatment systems, and decontamination of premise plumbing and appliances. The EPA research focused on decontamination of 1) Bacillus globigii (BG) spores, a non-pathogenic surrogate for Bacillus anthracis and 2) Bakken crude oil...
March 20, 2018: Journal—American Water Works Association
https://www.readbyqxmd.com/read/29681480/outcome-of-endodontic-surgery-a-meta-analysis-of-the-literature-part-3-comparison-of-endodontic-microsurgical-techniques-with-2-different-root-end-filling-materials
#17
REVIEW
Meetu R Kohli, Homayon Berenji, Frank C Setzer, Su-Min Lee, Bekir Karabucak
INTRODUCTION: The aim of the present study was to investigate the influence of root-end preparation and filling material on endodontic surgery outcome. A systematic review and meta-analysis was conducted to determine the outcome of resin-based endodontic surgery (RES, the use of high-magnification preparation of a shallow and concave root-end cavity and bonded resin-based root-end filling material) versus endodontic microsurgery (EMS, the use of high-magnification ultrasonic root-end preparation and root-end filling with SuperEBA [Keystone Industries, Gibbstown, NJ], IRM [Dentsply Sirona, York, PA], mineral trioxide aggregate [MTA], or other calcium silicate cements)...
April 19, 2018: Journal of Endodontics
https://www.readbyqxmd.com/read/29680952/functional-outcomes-of-robot-assisted-radical-prostatectomy-in-patients-eligible-for-active-surveillance
#18
Marc Zanaty, Khaled Ajib, Kevin Zorn, Assaad El-Hakim
OBJECTIVE: To assess the outcome of low risk prostate cancer (PCa) patients who were candidates for active surveillance (AS) but had undergone robot-assisted radical prostatectomy (RARP). METHOD: We reviewed our prospectively collected database of patients operated by RARP between 2006 and 2014. Low D'Amico risk patients were selected. Oncological outcomes were reported based on pathology results and biochemical failure. Functional outcomes on continence and potency were reported at 12 and 24 months...
April 21, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29680950/surgical-teaching-in-urology-patient-safety-and-educational-value-of-live-and-semi-live-surgical-demonstrations
#19
Jaap D Legemate, Stefano P Zanetti, Jan Erik Freund, Joyce Baard, Jean J M C H de la Rosette
PURPOSE: To evaluate the opinion of urologists and their audience regarding patient safety and educational value of live surgical demonstrations (LSD) and semi-live surgical demonstrations (semi-LSD). METHODS: Following the '2017 Challenges in Endourology' meeting, a survey addressing patient safety and the educational value of LSD and semi-LSD was disseminated online to all participants. Survey outcomes of LSD and semi-LSD were compared. RESULTS: All 279 respondents attended both LSD and semi-LSD...
April 21, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29680762/removal-and-fate-of-polycyclic-aromatic-hydrocarbons-in-a-hybrid-anaerobic-anoxic-oxic-process-for-highly-toxic-coke-wastewater-treatment
#20
Wentao Zhao, Qian Sui, Xia Huang
Elimination of polycyclic aromatic hydrocarbons (PAHs) from coke wastewater is crucial to minimize the PAHs contamination levels to the environment. Knowledge about the characteristics of PAHs removal in biological treatment processes, especially hybrid systems, for real coke wastewater treatment has been very scarce. In this study, a lab-scale hybrid anaerobic-anoxic-oxic (A1 /A2 /O) process was used to treat highly toxic coke wastewater and operated more than 600 d at total hydraulic retention time (HRT) of 50 h, 40 h, 30 h, 20 h and internal mixed liquor recirculation ratio (R) of 3, 6, 9...
April 19, 2018: Science of the Total Environment
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