R Kotecha, M W McDermott, C Chen, C Ferreira, S Hanft, C Shen, J Wanebo, K Smith, Z Wardak, T Patel, R Chamoun, K B Hoang, O Choutka, A Rodriguez, M Shah, D G Brachman, L Campbell, S Patel
PURPOSE/OBJECTIVE(S): Resection and intraoperative brachytherapy for patients with large, operable brain metastasis allows for both relief of mass effect and the delivery of radiotherapy (RT) to the resection cavity with a favorable dosimetric profile. The objective of this study was to analyze early patterns-of-care and treatment-related toxicity outcomes for brain metastasis patients treated with surgically targeted radiation therapy (STaRT) using a novel brachytherapy carrier. MATERIALS/METHODS: Patients with brain metastasis, de novo and recurrent disease, who enrolled onto a prospective multi-institutional observational study (NCT04427384) were the subject of this analysis...
October 1, 2023: International Journal of Radiation Oncology, Biology, Physics