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surgical treatment for intracerebral hemorrhage

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https://www.readbyqxmd.com/read/27907957/surgical-strategies-for-spontaneous-intracerebral-hemorrhage
#1
Wendy Ziai, J Ricardo Carhuapoma, Paul Nyquist, Daniel F Hanley
In recent decades, the medical and surgical treatment of intracerebral hemorrhage (ICH) have become the focus of a number of scientific investigations. This effort has been led by an international group of neurologists and neurosurgeons with the goal of studying functional recovery and developing new medical and surgical treatments to facilitate improved clinical outcomes. Currently, two of the most pressing ICH investigational goals are (1) early blood pressure control, and (2) safe hematoma volume reduction...
December 2016: Seminars in Neurology
https://www.readbyqxmd.com/read/27906525/the-clinical-utility-of-qsm-disease-diagnosis-medical-management-and-surgical-planning
#2
REVIEW
Sarah Eskreis-Winkler, Yan Zhang, Jingwei Zhang, Zhe Liu, Alexey Dimov, Ajay Gupta, Yi Wang
Quantitative susceptibility mapping (QSM) is an MR technique that depicts and quantifies magnetic susceptibility sources. Mapping iron, the dominant susceptibility source in the brain, has many important clinical applications. Herein, we review QSM applications in the diagnosis, medical management, and surgical treatment of disease. To assist in early disease diagnosis, QSM can identify elevated iron levels in the motor cortex of amyotrophic lateral sclerosis patients, in the substantia nigra of Parkinson's disease (PD) patients, in the globus pallidus, putamen, and caudate of Huntington's disease patients, and in the basal ganglia of Wilson's disease patients...
December 1, 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27899759/perioperative-antihypertensive-treatment-in-patients-with-spontaneous-intracerebral-hemorrhage
#3
Jun Zheng, Hao Li, Sen Lin, Junpeng Ma, Rui Guo, Lu Ma, Yuan Fang, Meng Tian, Ming Liu, Chao You
BACKGROUND: Studies on antihypertensive treatment for surgical patients with spontaneous intracerebral hemorrhage are insufficient. This pilot study was conducted to investigate the safety of the perioperative intensive blood pressure lowering in surgical patients with spontaneous intracerebral hemorrhage. METHODS: This study was a prospective, parallel, randomized, assessor-blinded trial. Patients allocated to the intensive group received perioperative intensive antihypertensive treatment aiming to achieve a target systolic blood pressure between 120 and 140 mm Hg, whereas the patients in the conservative group received conservative treatment aiming to achieve a target systolic blood pressure between 140 and 180 mm Hg for 7 days...
November 29, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27836703/surgical-treatment-of-traumatic-intracranial-aneurysms-experiences-at-a-single-center-over-30-years
#4
Seung-Hoon Jung, Sung-Hyun Kim, Tae-Sun Kim, Sung-Pil Joo
OBJECTIVE: Traumatic intracranial aneurysms (tIA) are rare and are associated with high rates of morbidity and mortality. We describe our experiences with tIA at our institution. METHODS: We retrospectively reviewed records from patients who underwent treatment for tIA between January 1986 and December 2015. RESULTS: Data from 5,532 patients diagnosed with cerebral aneurysms between January 1986 and December 2015 in our hospital were reviewed...
November 8, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27832176/recurrent-intracerebral-hemorrhage-associations-with-comorbidities-and-medicine-with-antithrombotic-effects
#5
Linnea Boegeskov Schmidt, Sanne Goertz, Jan Wohlfahrt, Mads Melbye, Tina Noergaard Munch
BACKGROUND: Intracerebral hemorrhage (ICH) is a disease with high mortality and a substantial risk of recurrence. However, the recurrence risk is poorly documented and the knowledge of potential predictors for recurrence among co-morbidities and medicine with antithrombotic effect is limited. OBJECTIVES: 1) To estimate the short- and long-term cumulative risks of recurrent intracerebral hemorrhage (ICH). 2) To investigate associations between typical comorbid diseases, surgical treatment, use of medicine with antithrombotic effects, including antithrombotic treatment (ATT), selective serotonin reuptake inhibitors (SSRI's), and nonsteroidal anti-inflammatory drugs (NSAID's) with recurrent ICH...
2016: PloS One
https://www.readbyqxmd.com/read/27815963/the-management-of-symptomatic-cerebral-developmental-venous-anomalies-a-clinical-experience-of-43-cases
#6
Xin-Guang Yu, Chen Wu, Hui Zhang, Zheng-Hui Sun, Zhi-Qiang Cui
BACKGROUND Developmental venous anomalies (DVAs) are rare vascular diseases becoming more frequently diagnosed. Most patients with DVAs have no clinical symptoms with the exception of a few patients with epilepsy, intracranial hemorrhage, or neuro-function deficit. There is still controversy with respect to treatment strategies for symptomatic DVAs. MATERIAL AND METHODS Forty-three cases of symptomatic DVAs from January 2006 to October 2015 were retrospectively reviewed and the imaging characteristics of DVAs by CT, MRI, and DSA and the treatment modalities for DVAs were studied...
November 5, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27799045/therapeutic-potential-of-drugs-targeting-pathophysiology-of-intracerebral-hemorrhage-from-animal-models-to-clinical-applications
#7
Kuo-Hsing Liao, Chih-Wei Sung, Ya-Ni Huang, Wei-Jiun Li, Po-Chuan Yu, Jia-Yi Wang
BACKGROUND: Intracerebral hemorrhage (ICH) is one of the most common forms of cerebral hemorrhage, the morbidity and death of ICH is high worldwide. ICH can be spontaneous or caused by hypertension, coagulopathy, angiopathy, head trauma, bleeding disorders, tumors, or drug usage. ICH is the most serious and least treatable form of hemorrhagic stroke, with rapidly increasing hematoma size and often resulting in significant brain injury and long term neurological deficits. Surgical hematoma evacuation remains controversial...
October 27, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27781045/local-fibrinolysis-in-spontaneous-supratentorial-hematomas-comparison-with-surgical-and-medical-treatment
#8
Eugeniu Condrea, Valeriu Timirgaz, Stanislav Groppa, Ion Codreanu, Natalia Rotaru
OBJECTIVE: To evaluate the effectiveness of minimally invasive craniopuncture with local fibrinolysis in the management of supratentorial spontaneous intracerebral hemorrhage (SICH). METHODS: The study included 218 consecutive patients with supratentorial SICH who were assigned to one of three groups: treated with minimally invasive craniopuncture with local fibrinolysis, treated with craniotomy or other minimally invasive techniques without local fibrinolysis, or receiving conservative management alone...
September 2016: Interventional Neurology
https://www.readbyqxmd.com/read/27755420/brain-abscess-following-intracerebral-hemorrhage-in-a-patient-with-pneumonia
#9
Kun Liu, Chunxia Yang, Yongna Zhang, Xunhui Yuan, Hang Xiao, Yun'an Bai, Bin Xi
Brain abscess is a rare but potentially lethal infection of brain parenchyma, requiring prompt surgical intervention and high-dose antibiotic therapy. Brain abscess is a known complication of surgically treated intracerebral hemorrhage (ICH), but it is exceptionally rare that it occurs at the same site of a nonoperated ICH. Such cases may result from hematogenous spread from distant foci (pneumonia, infectious endocarditis) or contiguous sites. Herein, the authors report a case of 75-year-old woman presenting with a brain abscess 6 weeks after a nonoperated ICH...
October 14, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27747001/outcomes-of-different-treatments-on-takayasu-s-arteritis
#10
Yu Xiao, Jian Zhou, Xiaolong Wei, Yudong Sun, Lei Zhang, Jiaxuan Feng, Rui Feng, Zhiqing Zhao, Zaiping Jing
BACKGROUND: Takayasu's arteritis (TA) is a nonspecific chronic inflammation of the aorta and its branches. This study compared the outcomes of surgical treatments including bypass surgery, cutting balloon angioplasty and conventional balloon angioplasty to TA patients exhibiting supra-aortic arterial (SAA). METHODS: This retrospective study was conducted on 42 TA patients, obtained from hospital database, who underwent surgical therapy due to SAA lesions from January 2010 to March 2015...
September 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27743763/-fatal-central-nervous-system-hemorrhage-during-acute-lymphoblastic-leukemia-induction
#11
P Pardes-Chavanes, M Afanetti, C Boyer, M Poirée
Intracerebral hemorrhage (ICH) remains a cause of death in hematologic malignancies. Asparaginase represents a key agent in the treatment of acute lymphoblastic leukemia (ALL). The toxicity of asparaginase includes coagulopathy such as thrombotic or bleeding tendency. We report a case of fatal cerebral hemorrhage in a 12-year-old girl treated for ALL. Cerebral hemorrhage occurred after three injections of L-asparaginase. The patient presented with hypofibrinogenemia (0.36g/L), associated with thrombocytopenia (24,000/mm(3))...
October 12, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27740983/imaging-of-hemorrhagic-stroke
#12
Ryan Hakimi, Ankur Garg
PURPOSE OF REVIEW: Hemorrhagic stroke comprises approximately 15% to 20% of all strokes. This article provides readers with an understanding of the indications and significance of various neuroimaging techniques available for patients presenting with hemorrhagic strokes of distinct causes. RECENT FINDINGS: The most common initial neuroimaging study is a noncontrast head CT, which allows for the identification of hemorrhage. Once an intracranial hemorrhage has been identified, the pattern of blood and the patient's medical history, neurologic examination, and laboratory studies lead the practitioner to pursue further neuroimaging studies to guide the medical, surgical, and interventional management...
October 2016: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/27640182/the-critical-care-management-of-spontaneous-intracranial-hemorrhage-a-contemporary-review
#13
REVIEW
Airton Leonardo de Oliveira Manoel, Alberto Goffi, Fernando Godinho Zampieri, David Turkel-Parrella, Abhijit Duggal, Thomas R Marotta, R Loch Macdonald, Simon Abrahamson
Spontaneous intracerebral hemorrhage (ICH), defined as nontraumatic bleeding into the brain parenchyma, is the second most common subtype of stroke, with 5.3 million cases and over 3 million deaths reported worldwide in 2010. Case fatality is extremely high (reaching approximately 60 % at 1 year post event). Only 20 % of patients who survive are independent within 6 months. Factors such as chronic hypertension, cerebral amyloid angiopathy, and anticoagulation are commonly associated with ICH. Chronic arterial hypertension represents the major risk factor for bleeding...
September 18, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27639680/oxidative-stress-and-inflammation-in-cerebral-cavernous-malformation-disease-pathogenesis-two-sides-of-the-same-coin
#14
Saverio Francesco Retta, Angela J Glading
Cerebral Cavernous Malformation (CCM) is a vascular disease of proven genetic origin, which may arise sporadically or is inherited as an autosomal dominant condition with incomplete penetrance and highly variable expressivity. CCM lesions exhibit a range of different phenotypes, including wide inter-individual differences in lesion number, size, and susceptibility to intracerebral hemorrhage (ICH). Lesions may remain asymptomatic or result in pathological conditions of various type and severity at any age, with symptoms ranging from recurrent headaches to severe neurological deficits, seizures, and stroke...
September 14, 2016: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/27637624/flexible-endoscopic-aspiration-for-intraventricular-casting-hematoma
#15
Terushige Toyooka, Hiroshi Kageyama, Nobusuke Tsuzuki, Shoichiro Ishihara, Kazunari Oka
BACKGROUND: Conventionally, patients suffering a massive intraventricular hemorrhage have undergone external ventricular drainage. However, long-term or repeated drainage increases the risk of complications due to infections or shunt dependency. Neuroendoscopic surgery may offer some advantages over more conventional procedures. METHODS: Thirteen patients suffering intraventricular hematoma associated with intracerebral hemorrhage, treated in our hospital between April 2011 and March 2014, were reviewed retrospectively...
2016: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/27637622/surgical-management-of-aneurysmal-hematomas-prognostic-factors-and-outcome
#16
P Meneghelli, F Cozzi, A Hasanbelliu, F Locatelli, Alberto Pasqualin
From 1991 until 2013, 304 patients with intracranial hematomas from aneurysmal rupture were managed surgically in our department, constituting 17 % of all patients with aneurysmal rupture. Of them, 242 patents presented with isolated intracerebral hematomas (in 69 cases associated with significant intraventricular hemorrhage), 50 patients presented with combined intracerebral and subdural hematomas (in 11 cases associated with significant intraventricular hemorrhage), and 12 presented with an isolated subdural hematoma...
2016: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/27609451/investigating-the-role-of-ethnicity-and-race-among-patients-undergoing-treatment-for-intracerebral-aneurysms-between-2008-2013-from-a-national-database
#17
Roxanna M Garcia, Seungwon Yoon, Matthew B Potts, Michael T Lawton
BACKGROUND: The objective of this study is to classify patients using federally mandated categories of ethnicity and race and to determine if subgroups are associated with patient outcomes and aneurysmal subarachnoid hemorrhage (SAH). METHODS: The American College of Surgeons National Surgical Quality Improvement Program database from 2008 to 2013 was utilized to identify patients undergoing treatment of an intracerebral aneurysm. Ethnicity and race were combined to create subgroups...
September 5, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27583176/predictors-of-30-day-mortality-in-patients-with-spontaneous-primary-intracerebral-hemorrhage
#18
Diaa A Safatli, Albrecht Günther, Peter Schlattmann, Falko Schwarz, Rolf Kalff, Christian Ewald
BACKGROUND: Intracerebral hemorrhage (ICH) is a life threatening entity, and an early outcome assessment is mandatory for optimizing therapeutic efforts. METHODS: We retrospectively analyzed data from 342 patients with spontaneous primary ICH to evaluate possible predictors of 30-day mortality considering clinical, radiological, and therapeutical parameters. We also applied three widely accepted outcome grading scoring systems [(ICH score, FUNC score and intracerebral hemorrhage grading scale (ICH-GS)] on our population to evaluate the correlation of these scores with the 30-day mortality in our study...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27399465/186%C3%A2-deferoxamine-accelerates-hemorrhage-absorption-for-patients-with-traumatic-intracerebral-hematoma-a-prospective-randomized-controlled-trial
#19
Jian Yu
INTRODUCTION: Traumatic brain injury (TBI) is a common disease for adults, particularly for young people. Most TBI patients have intracerebral hemorrhage, which often to brain edema and toxicity to the neural tissue. Deferoxamine (also known as Deferrioxamine B, Deferoxamine B, DFO-B, DFOA, DFB or desferal, DFX) is a bacterial siderophore produced by the Actinobacteria Streptomyces pilosus. It has medical applications as a chelating agent used to remove excess iron from the body. Animal models indicate that Deferoxamine accelerates intracranial hemorrhage absorption, although its effects on human patients remain unclear...
August 2016: Neurosurgery
https://www.readbyqxmd.com/read/27373415/treatment-strategies-to-attenuate-perihematomal-edema-in-patients-with-intracerebral-hemorrhage
#20
Hoon Kim, Nancy J Edwards, Huimahn A Choi, Tiffany R Chang, Kwang Wook Jo, Kiwon Lee
Spontaneous intracerebral hemorrhage (SICH) continues to be a significant cause of neurologic morbidity and mortality throughout the world. Although recent advances in the treatment of SICH have significantly decreased mortality rates, functional recovery has not been dramatically improved by any intervention to date. There are two predominant mechanisms of brain injury from ICH: mechanical injury from the primary hematoma (including growth of that hematoma), and secondary injury from perihematomal inflammation...
June 29, 2016: World Neurosurgery
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