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https://www.readbyqxmd.com/read/29655780/dietary-flavonoid-kaempferol-inhibits-glucocorticoid-induced-bone-loss-by-promoting-osteoblast-survival
#1
Sulekha Adhikary, Dharmendra Choudhary, Naseer Ahmad, Anirudha Karvande, Avinash Kumar, Venkatesh Teja Banala, Prabhat Ranjan Mishra, Ritu Trivedi
OBJECTIVE: Kaempferol, a dietary flavonoid found in fruits and vegetables, has been reported to reverse osteopenic condition in ovariectomized rats. Because kaempferol is endowed with osteogenic activity, the aim of this study was to determine whether it has a beneficial effect on glucocorticoid (GC)-induced bone loss. METHODS: Adult female rats were divided into four groups as control (vehicle; distilled water), methylprednisolone (MP; 5 mg•kg•d, subcutaneously), MP + kaempferol (5 mg•kg•d, oral), and MP + human parathyroid 1-34 (30 µg/kg, 5 times/wk, subcutaneously) and treated for 4 wk...
February 13, 2018: Nutrition
https://www.readbyqxmd.com/read/29653438/the-effect-of-a-cricket-fielding-session-on-glenohumeral-range-of-motion-and-active-joint-position-sense
#2
Liam Newton, Steve McCaig
OBJECTIVE: To assess the effects of a cricket fielding session, at an identified throwing injury risk workload, on shoulder joint position sense (JPS) and active range of motion (AROM) in cricketers. DESIGN: Repeated measures observational study. SETTING: Indoor cricket centre. PARTICIPANTS: Nineteen, asymptomatic University cricketers. MAIN OUTCOME: AROM was assessed supine at 90° abduction and from this 10% off end range IR and ER was used as the position matching angle to assess JPS...
April 4, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29653424/methane-in-groundwater-from-a-leaking-gas-well-piceance-basin-colorado-usa
#3
Peter B McMahon, Judith C Thomas, John T Crawford, Mark M Dornblaser, Andrew G Hunt
Site-specific and regional analysis of time-series hydrologic and geochemical data collected from 15 monitoring wells in the Piceance Basin indicated that a leaking gas well contaminated shallow groundwater with thermogenic methane. The gas well was drilled in 1956 and plugged and abandoned in 1990. Chemical and isotopic data showed the thermogenic methane was not from mixing of gas-rich formation water with shallow groundwater or natural migration of a free-gas phase. Water-level and methane-isotopic data, and video logs from a deep monitoring well, indicated that a shale confining layer ~125m below the zone of contamination was an effective barrier to upward migration of water and gas...
April 10, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29652836/a-fast-and-on-machine-measuring-system-using-the-laser-displacement-sensor-for-the-contour-parameters-of-the-drill-pipe-thread
#4
Zhixu Dong, Xingwei Sun, Changzheng Chen, Mengnan Sun
The inconvenient loading and unloading of a long and heavy drill pipe gives rise to the difficulty in measuring the contour parameters of its threads at both ends. To solve this problem, in this paper we take the SCK230 drill pipe thread-repairing machine tool as a carrier to design and achieve a fast and on-machine measuring system based on a laser probe. This system drives a laser displacement sensor to acquire the contour data of a certain axial section of the thread by using the servo function of a CNC machine tool...
April 13, 2018: Sensors
https://www.readbyqxmd.com/read/29652631/-this-is-not-a-drill-activation-of-a-student-led-influenza-vaccination-point-of-distribution
#5
Lavonne M Adams, Sharon Canclini, Kelle Tillman
OBJECTIVE: To describe activation of a Point of Distribution (POD) in response to an influenza outbreak, highlighting the use of a student-led model. PARTICIPANTS: Faculty, staff, and students of X College of Nursing and Health Sciences, X University, as well as those located in its primary building. METHODS: In response to an August 2017 influenza outbreak, a vaccination clinic was conducted for a target population through POD activation...
April 13, 2018: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/29652234/computer-assisted-planning-for-the-insertion-of-stereoelectroencephalography-electrodes-for-the-investigation-of-drug-resistant-focal-epilepsy-an-external-validation-study
#6
Vejay N Vakharia, Rachel Sparks, Roman Rodionov, Sjoerd B Vos, Christian Dorfer, Jonathan Miller, Daniel Nilsson, Martin Tisdall, Stefan Wolfsberger, Andrew W McEvoy, Anna Miserocchi, Gavin P Winston, Aidan G O'Keeffe, Sebastien Ourselin, John S Duncan
OBJECTIVE One-third of cases of focal epilepsy are drug refractory, and surgery might provide a cure. Seizure-free outcome after surgery depends on the correct identification and resection of the epileptogenic zone. In patients with no visible abnormality on MRI, or in cases in which presurgical evaluation yields discordant data, invasive stereoelectroencephalography (SEEG) recordings might be necessary. SEEG is a procedure in which multiple electrodes are placed stereotactically in key targets within the brain to record interictal and ictal electrophysiological activity...
April 13, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29652139/estimated-emissions-from-the-prime-movers-of-unconventional-natural-gas-well-development-using-recently-collected-in-use-data-in-the-united-states
#7
Derek Johnson, Robert Heltzel, Andrew Nix, Mahdi Darzi, Dakota Oliver
Natural gas from shale plays dominates new production and growth. However, unconventional well development is an energy intensive process. The prime movers, which include over-the-road service trucks, horizontal drilling rigs, and hydraulic fracturing pumps, are predominately powered by diesel engines that impact air quality. Instead of relying on certification data or outdated emission factors, this model uses new in-use emissions and activity data combined with historical literature to develop a national emissions inventory...
April 13, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29651072/book-review-licensed-to-drill
#8
Andrew Geddis-Regan
No abstract text is available yet for this article.
April 13, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29650990/disclosing-the-temperature-of-columnar-jointing-in-lavas
#9
Anthony Lamur, Yan Lavallée, Fiona E Iddon, Adrian J Hornby, Jackie E Kendrick, Felix W von Aulock, Fabian B Wadsworth
Columnar joints form by cracking during cooling-induced contraction of lava, allowing hydrothermal fluid circulation. A lack of direct observations of their formation has led to ambiguity about the temperature window of jointing and its impact on fluid flow. Here we develop a novel thermo-mechanical experiment to disclose the temperature of columnar jointing in lavas. Using basalts from Eyjafjallajökull volcano (Iceland) we show that contraction during cooling induces stress build-up below the solidus temperature (980 °C), resulting in localised macroscopic failure between 890 and 840 °C...
April 12, 2018: Nature Communications
https://www.readbyqxmd.com/read/29650879/-a-study-on-designs-and-achievements-of-trainings-for-enhancing-the-self-help-ability-of-home-cared-persons-in-preparing-for-disasters-review-of-disaster-drills-with-cared-persons-and-their-families
#10
Kayo Shirai, Mieko Ito, Kiyomi Hata
After the Great East Japan Earthquake, we re-recognized the importance of self-help efforts of home-cared persons and their families and the necessity of advanced measures. In 2013, we designed a disaster drill to enhance the self-help ability of home-cared persons and their families in a stepwise fashion. In 2016, for the purpose of reviewing the achievements of the designed drill and its contents, the disaster drill was conducted on 21 users of our home-visit nursing station, followed by a questionnaire survey regarding the training contents, date/time, documents used, change in awareness, disaster-preventive actions, etc...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29649900/in-vitro-comparison-of-a-novel-single-probe-dual-energy-lithotripter-to-current-devices
#11
Evan Clayton Carlos, Daniel A Wollin, Brenton B Winship, Ruiyang Jiang, Daniela Radvak, Ben H Chew, Michael R Gustafson, W Neal Simmons, Pei Zhong, Glenn M Preminger, Michael Eric Lipkin
PURPOSE: The LithoClast Trilogy is a novel single probe, dual-energy lithotripter with ultrasonic vibration and electromagnetic impact forces. ShockPulse and LithoClast Select are existing lithotripters that also use a combination of ultrasonic and mechanical impact energies. We compared the efficacy and tip motion of these devices in an in vitro setting. MATERIALS AND METHODS: 15:3 Begostones were used in all trials. Test groups were Trilogy, ShockPulse, Select ultrasound only (Select-US) and Select ultrasound with pneumatic (Select-USP)...
April 13, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29644899/technical-notes-on-the-endoscopic-endonasal-approach-to-the-craniovertebral-junction-for-odontoidectomy
#12
Dennis Tang, Christopher Roxbury, Brian D'Anza, Varun Kshettry, Troy Woodard, Pablo Recinos, Raj Sindwani
INTRODUCTION: Odontoidectomy can help decompress ventral compression of the brainstem and upper cervical spinal cord in the presence of bony abnormalities of the craniovertebral junction (CVJ), e.g., an odontoid pannus. Endonasal approaches have been shown to be associated with lower morbidity compared with traditional transoral approaches. We demonstrated an entirely endonasal approach to the CVJ. MATERIALS AND METHODS: We presented our technique for performing an endoscopic endonasal odontoidectomy...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29644289/transpedicular-direct-osteosynthesis-of-hangman-s-fracture-from-a-mini-open-exposure-as-a-less-invasive-procedure-a-technical-note
#13
Viktor Zsolt Kovari, Attila Josvai, Andras Csokay
This surgical technical case report presents initial clinical experience and preliminary results with a less invasive surgical solution for selected hangman's fracture. A well-known stabilization technique (i.e. direct transpedicular osteosynthesis) was applied through a minimally invasive small incision transmuscular posterior approach guided by a standard C-arm fluoroscopy. This mini-open approach to C2 vertebra allows similar dissection, visualization of the bony landmarks, visual control of the transpedicular screw path drilling, tapping and screw insertion to the standard posterior cervical spine approach...
December 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29628668/evaluation-of-change-in-knowledge-and-attitude-of-emergency-medicine-residents-after-introduction-of-a-rotation-in-emergency-medical-services-and-disaster-medicine
#14
Nawfal Aljerian, Aamir Omair, Sami A Yousif, Abdulrahman S Alqahtani, Faisal A Alhusain, Bader Alotaibi, Mohammad F Alshehri, Majed Aljuhani, Saad Albaiz, Yasser Alaska, Abdullah F Alanazi
Background: Saudi Board of Emergency Medicine (SBEM) graduates are involved in a 1-month rotation in emergency medical services (EMSs) and disaster medicine. The purpose of this study was to evaluate change in knowledge and attitude of EM residents after the introduction of the EMS and disaster medicine rotation. Materials and Methods: The study included 32 3rd -year SBEM residents. A pretest/posttest design and a five-point Likert scale were used. The data included a response to a questionnaire developed by EMS and disaster experts...
January 2018: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29628423/micrographic-study-and-torsional-strength-of-grade-23-titanium-mini-implants-recycled-for-orthodontic-purposes
#15
Nadir Kaci, Karima Hakem, Safia Laraba, Nasser Benrekaa, Michel Le Gall
INTRODUCTION: The aim of this study was to identify the fracture resistance of grade 23 Titanium mini-implants recycled for orthodontic purposes and having stayed in the mouth during different periods of time. MATERIALS AND METHODS: A total of 52 hybrid-designed titanium mini-implants, threaded length L=8mm, self-drilling and self-taping were used in 32 patients presenting orthodontic anomalies which required the use of mini-implants. Two types of tests were performed: polarizing optical imagery to assess the surface characteristics of the mini-implants (polarizing optical microscopy) and (mechanical) torsional strength tests, more quantitative, in order to establish the breaking point of the mini-implants during their re-use...
April 5, 2018: International Orthodontics
https://www.readbyqxmd.com/read/29627398/anatomical-investigations-on-intraosseous-access-in-stillborns-comparison-of-different-devices-and-techniques
#16
Zeynep Fuchs, Martin Scaal, Heinz Haverkamp, Friederike Koerber, Thorsten Persigehl, Frank Eifinger
AIM: Intraosseous (IO)-access plays an alternative route during resuscitation. Our study was performed to investigate the successful rate of IO-access in preterm and term stillborns using different devices and techniques. METHODS: The cadavers used were legal donations. 16 stillborns, median: 29.2weeks (IQR 27.2-38.4) were investigated. Two different needles (a: Butterfly needle,21G,Venofix® Fa.Braun; b: Arrow® EZ-IO® 15G, Teleflex,Dublin,Ireland) were used. Needles were inserted i: manually, using a Butterfly needle; ii: manually, using EZ-IO® needle or iii: using a battery-powered semi-automatic drill (Arrow® EZ-IO® )...
April 5, 2018: Resuscitation
https://www.readbyqxmd.com/read/29627367/development-of-a-patient-specific-temporomandibular-joint-prosthesis-according-to-the-groningen-principle-through-a-cadaver-test-series
#17
J Kraeima, B J Merema, M J H Witjes, F K L Spijkervet
OBJECTIVES: Patients suffering from osteoarthritis, ankylosis (e.g. post-trauma or tumour) in the temporomandibular joint (TMJ) can present with symptoms such as severely restricted mouth opening, pain or other dynamic restrictions of the mandible. To alleviate the symptoms, a total joint prosthesis can be indicated, such as the Groningen TMJ prosthesis. This was developed as a stock device with a lowered centre of rotation for improved translational and opening capacity. This study aimed to improve the design of the prosthesis, and produce a workflow for a customized Groningen TMJ prosthesis, in order to make it more accurate and predictable...
March 14, 2018: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29625752/linear-magnetic-clutch-to-automatically-control-torque-output
#18
Nan-Chyuan Tsai, Chi-Ting Yeh, Hsin-Lin Chiu
A novel eddy-current Magnetic Clutch (MC) unit with its torque-adjustable mechanism is proposed by this research. As to mechanical structure, the MC unit is mainly constituted by a squirrel-cage inner rotor and a magnet-embedded outer rotor. The transmitted output torque can be adjusted by either the Overlapped Length (OL) or the relative angular velocity between outer rotor and inner rotor. Firstly, the mathematical model of the MC system is developed. Secondly, the features and characterization of the MC unit are explored by intensive experiments under various overlapped length and relative rotational speed between inner rotor and outer rotor...
April 3, 2018: ISA Transactions
https://www.readbyqxmd.com/read/29625048/cell-of-origin-patterns-dominate-the-molecular-classification-of-10-000-tumors-from-33-types-of-cancer
#19
Katherine A Hoadley, Christina Yau, Toshinori Hinoue, Denise M Wolf, Alexander J Lazar, Esther Drill, Ronglai Shen, Alison M Taylor, Andrew D Cherniack, Vésteinn Thorsson, Rehan Akbani, Reanne Bowlby, Christopher K Wong, Maciej Wiznerowicz, Francisco Sanchez-Vega, A Gordon Robertson, Barbara G Schneider, Michael S Lawrence, Houtan Noushmehr, Tathiane M Malta, Joshua M Stuart, Christopher C Benz, Peter W Laird
We conducted comprehensive integrative molecular analyses of the complete set of tumors in The Cancer Genome Atlas (TCGA), consisting of approximately 10,000 specimens and representing 33 types of cancer. We performed molecular clustering using data on chromosome-arm-level aneuploidy, DNA hypermethylation, mRNA, and miRNA expression levels and reverse-phase protein arrays, of which all, except for aneuploidy, revealed clustering primarily organized by histology, tissue type, or anatomic origin. The influence of cell type was evident in DNA-methylation-based clustering, even after excluding sites with known preexisting tissue-type-specific methylation...
April 5, 2018: Cell
https://www.readbyqxmd.com/read/29625029/how-much-noise-is-an-oral-and-maxillofacial-surgeon-exposed-to
#20
Esha Kulkarni, Yasmine Abdallah, Dennis Hanseman, Deepak G Krishnan
PURPOSE: A common concern among oral and maxillofacial surgeons (OMSs) is progressive hearing loss throughout their careers. Although this has not been critically studied, there could be several factors that contribute to this detriment, including drills, saws, suction, music, and other sounds within the closed operating environment. This study observed the intensity of noise in operating rooms (ORs) and clinical settings during the use of drills, saws, surgical handpieces, and other tools...
March 14, 2018: Journal of Oral and Maxillofacial Surgery
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