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https://www.readbyqxmd.com/read/28934831/pneumoretroperitoneum-pneumomediastinum-pneumothorax-and-subcutaneous-emphysema-after-diagnostic-colonoscopy
#1
Hee Sung Lee, Hwan Hee Park, Ju Seok Kim, Sun Hyung Kang, Hee Seok Moon, Jae Kyu Sung, Byung Seok Lee, Hyun Yong Jeong
Colonoscopy is a commonly performed endoscopic procedure. Although it is generally considered to be safe, serious complications, such as colorectal perforation, can occur. Most colonic perforations are intraperitoneal and cause pneumoperitoneum with acute abdominal pain as the initial symptom. However, extraperitoneal perforations with pneumoretroperitoneum may happen, albeit rarely, with atypical initial symptoms. We report a rare case of rectosigmoid perforation occurring after diagnostic colonoscopy that developed into pneumoretroperitoneum, pneumomediastinum, pneumothorax, and subcutaneous emphysema, with a change in voice and neck swelling as the initial symptoms...
September 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28934802/intravertebral-vacuum-cleft-and-its-varied-locations-within-osteoporotic-vertebral-compression-fractures-effect-on-therapeutic-efficacy
#2
Weibo Yu, Xiaobing Jiang, De Liang, Zhensong Yao, Ting Qiu, Linqiang Ye, Shuncong Zhang, Daxiang Jin
BACKGROUND: Previous studies have reported a high incidence of re-collapse of the augmented vertebrae after percutaneous vertebral augmentation (PVA) for osteoporotic vertebral compression fractures (OVCFs) with intravertebral vacuum cleft (IVC) during long-term follow-up. Previous IVC might be considered an important predisposing factor for re-collapse, but the prior studies could not find a significant correlation. OBJECTIVE: To determine the incidence and distribution characteristics of IVCs and to further assess IVCs in their varied locations...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934784/sonographic-guidance-for-supraclavicular-brachial-plexus-blocks-single-vs-double-injection-cluster-approach
#3
Jung Ju Choi, Hyun Jeong Kwak, Wol Seon Jung, Seung Hyun Chung, Mi Geum Lee
BACKGROUND: The cluster approach for supraclavicular brachial plexus block (SC-BPB) can be easily performed but may result in asymmetric local anesthetic (LA) spread. The authors hypothesized that the use of a cluster approach in each of the 2 planes would achieve better 3-dimensional LA distribution than the traditional single cluster approach. OBJECTIVES: The purpose of the present study was to compare a double injection (DI) in 2 planes (one injection in each plane) with the traditional single injection (SI) cluster approach for ultrasound-guided SC-BPB...
September 2017: Pain Physician
https://www.readbyqxmd.com/read/28934728/has-toxicity-testing-moved-into-the-21st-century-a-survey-and-analysis-of-perceptions-in-the-field-of-toxicology
#4
Virginia Zaunbrecher, Elizabeth Beryt, Daniela Parodi, Donatello Telesca, Joseph Doherty, Timothy Malloy, Patrick Allard
BACKGROUND: Ten years ago, leaders in the field of toxicology called for a transformation of the discipline and a shift from primarily relying on traditional animal testing to incorporating advances in biotechnology and predictive methodologies into alternative testing strategies (ATS). Governmental agencies and academic and industry partners initiated programs to support such a transformation, but a decade later, the outcomes of these efforts are not well understood. OBJECTIVES: We aimed to assess the use of ATS and the perceived barriers and drivers to their adoption by toxicologists and by others working in, or closely linked with, the field of toxicology...
August 30, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28934693/enzyme-classification-using-multiclass-support-vector-machine-and-feature-subset-selection
#5
Debasmita Pradhan, Sudarsan Padhy, Biswajit Sahoo
Proteins are the macromolecules responsible for almost all biological processes in a cell. With the availability of large number of protein sequences from different sequencing projects, the challenge with the scientist is to characterize their functions. As the wet lab methods are time consuming and expensive, many computational methods such as FASTA, PSI-BLAST, DNA microarray clustering, and Nearest Neighborhood classification on protein-protein interaction network have been proposed. Support vector machine is one such method that has been used successfully for several problems such as protein fold recognition, protein structure prediction etc...
August 31, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28934651/persulfate-enhanced-photocatalytic-degradation-of-bisphenol-a-by-g-c3n4-nanosheets-under-visible-light-irradiation
#6
Bochuan Liu, Meng Qiao, Yanbin Wang, Lijuan Wang, Yan Gong, Tao Guo, Xu Zhao
The enhancement of g-C3N4 photocatalytic degradation of bisphenol A (BPA) via persulfate (PS) addition was investigated under visible light irradiation. The effects of various parameters on the BPA degradation were investigated, such as catalysts dosage, PS concentrations, initial pH value and BPA concentration. The results showed that g-C3N4 nanosheets exhibited superior photocatalytic activity toward BPA degradation as compared with bulk g-C3N4. The addition of PS can further improve the g-C3N4 photocatalytic performance for BPA degradation...
September 4, 2017: Chemosphere
https://www.readbyqxmd.com/read/28934619/distinct-brain-metabolic-patterns-separately-associated-with-cognition-motor-function-and-aging-in-parkinson-s-disease-dementia
#7
Ji Hyun Ko, Audrey Katako, Maram Aljuaid, Andrew L Goertzen, Andrew Borys, Douglas E Hobson, Seok Min Kim, Chong Sik Lee
We explored whether patients with Parkinson's disease dementia (PDD) show a distinct spatial metabolic pattern that characterizes cognitive deficits in addition to motor dysfunction. Eighteen patients with PDD underwent 3 separate positron emission tomography sessions with [(18)F]fluorodeoxyglucose (for glucose metabolism), fluorinated N-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane (for dopamine transporter density) and Pittsburgh compound-B (for beta-amyloid load). We confirmed in PDD versus normal controls, overall hypometabolism in the posterior and prefrontal brain regions accompanied with hypermetabolism in subcortical structures and the cerebellar vermis...
August 31, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28934535/quantification-of-imaging-error-in-the-measurement-of-cup-position-a-cadaveric-comparison-of-radiographic-and-computed-tomography-imaging
#8
Ran Schwarzkopf, Jonathan M Vigdorchik, Theodore T Miller, Eric A Bogner, Jeffrey M Muir, Michael B Cross
Postoperative radiographs remain the standard for assessment of component placement following total hip arthroplasty (THA), despite the known limitations of radiographs. Computed tomography (CT) scanning offers improved accuracy, but its costs and radiation exposure are prohibitive. The authors performed a cadaver study to compare the error associated with radiographs with that of CT scans following THA. The authors also compared imaging with a novel mini-navigation system. Three board-certified orthopedic surgeons each performed 4 THA procedures (6 cadavers, 12 hips) via the posterior approach using a mini-navigation tool to assist with component placement...
September 21, 2017: Orthopedics
https://www.readbyqxmd.com/read/28934530/intraindividual-increase-of-homeostatic-sleep-pressure-across-acute-and-chronic-sleep-loss-a-high-density-eeg-study
#9
Angelina Maric, Caroline Lustenberger, Esther Werth, Christian R Baumann, Rositsa Poryazova, Reto Huber
Study Objectives: To compare intraindividually the effects of acute sleep deprivation (ASD) and chronic sleep restriction (CSR) on the homeostatic increase in slow wave activity (SWA) and to relate it to impairments in basic cognitive functioning, that is, vigilance. Methods: The increase in SWA after ASD (40 hours of wakefulness) and after CSR (seven nights with time in bed restricted to 5 hours per night) relative to baseline sleep was assessed in nine healthy, male participants (age = 18-26 years) by high-density electroencephalography...
September 1, 2017: Sleep
https://www.readbyqxmd.com/read/28934457/highly-pathogenic-avian-influenza-a-h5n1-viruses-at-the-animal-human-interface-in-vietnam-2003-2010
#10
Adrian Creanga, Nguyen Le Khanh Hang, Vuong Duc Cuong, Ha T Nguyen, Hoang Vu Mai Phuong, Le Thi Thanh, Nguyen Co Thach, Pham Thi Hien, Nguyen Tung, Yunho Jang, Amanda Balish, Nguyen Hoang Dang, Mai Thuy Duong, Ngo Thu Huong, Do Ngoc Hoa, Nguyen Dang Tho, Alexander Klimov, Bryan K Kapella, Larisa Gubareva, James C Kile, Nguyen Tran Hien, Le Quynh Mai, C Todd Davis
Mutation and reassortment of highly pathogenic avian influenza A(H5N1) viruses at the animal-human interface remain a major concern for emergence of viruses with pandemic potential. To understand the relationship of H5N1 viruses circulating in poultry and those isolated from humans, comprehensive phylogenetic and molecular analyses of viruses collected from both hosts in Vietnam between 2003 and 2010 were performed. We examined the temporal and spatial distribution of human cases relative to H5N1 poultry outbreaks and characterized the genetic lineages and amino acid substitutions in each gene segment identified in humans relative to closely related viruses from avian hosts...
September 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28934422/low-frequency-of-acquired-isoniazid-and-rifampicin-resistance-in-rifampicin-susceptible-pulmonary-tuberculosis-in-a-setting-of-high-hiv-1-infection-and-tuberculosis-coprevalence
#11
Neesha Rockwood, Frederick Sirgel, Elizabeth Streicher, Robin Warren, Graeme Meintjes, Robert J Wilkinson
Background: We estimated the incidence of acquired isoniazid and rifampicin resistance in rifampicin-susceptible tuberculosis in a setting of high human immunodeficiency virus type 1 (HIV-1) infection and tuberculosis coprevalence. Methods: GeneXpert MTB/RIF-confirmed patients with rifampicin-susceptible tuberculosis were recruited at antituberculosis treatment initiation in Khayelitsha, South Africa. Liquid culture and adherence assessment were performed at 2 and 5-6 months...
September 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28934258/reports-of-unintended-consequences-of-financial-incentives-to-improve-management-of-hypertension
#12
Sylvia J Hysong, Richard SoRelle, Kristen Broussard Smitham, Laura A Petersen
BACKGROUND: Given the increase in financial-incentive programs nationwide, many physicians and physician groups are concerned about potential unintended consequences of providing financial incentives to improve quality of care. However, few studies examine whether actual unintended consequences result from providing financial incentives to physicians. We sought to document the extent to which the unintended consequences discussed in the literature were observable in a randomized clinical trial (RCT) of financial incentives...
2017: PloS One
https://www.readbyqxmd.com/read/28934241/hla-dr7-and-hla-dq2-transgenic-mouse-strains-tested-as-a-model-system-for-ximelagatran-hepatotoxicity
#13
Hanna Lundgren, Klara Martinsson, Karin Cederbrant, Johan Jirholt, Daniel Mucs, Katja Madeyski-Bengtson, Said Havarinasab, Per Hultman
The oral thrombin inhibitor ximelagatran was withdrawn in the late clinical trial phase because it adversely affected the liver. In approximately 8% of treated patients, drug-induced liver injury (DILI) was expressed as transient alanine transaminase (ALT) elevations. No evidence of DILI had been revealed in the pre-clinical in vivo studies. A whole genome scan study performed on the clinical study material identified a strong genetic association between the major histocompatibility complex alleles for human leucocyte antigens (HLA) (HLA-DR7 and HLA-DQ2) and elevated ALT levels in treated patients...
2017: PloS One
https://www.readbyqxmd.com/read/28934166/is-branched-chain-amino-acids-supplementation-an-efficient-nutritional-strategy-to-alleviate-skeletal-muscle-damage-a-systematic-review
#14
REVIEW
Alexandre Fouré, David Bendahan
Amino acids and more precisely, branched-chain amino acids (BCAAs), are usually consumed as nutritional supplements by many athletes and people involved in regular and moderate physical activities regardless of their practice level. BCAAs have been initially shown to increase muscle mass and have also been implicated in the limitation of structural and metabolic alterations associated with exercise damage. This systematic review provides a comprehensive analysis of the literature regarding the beneficial effects of BCAAs supplementation within the context of exercise-induced muscle damage or muscle injury...
September 21, 2017: Nutrients
https://www.readbyqxmd.com/read/28934015/initial-clinical-experience-with-dual-agent-relaxation-contrast-for-isolated-lymphatic-channel-mapping
#15
Beth Ripley, Gregory J Wilson, Neeraj Lalwani, Noah Briller, Peter C Neligan, Jeffrey H Maki
Purpose To evaluate the clinical performance of dual-agent relaxation contrast (DARC) magnetic resonance (MR) lymphangiography compared with that of conventional MR lymphangiography in the creation of isolated lymphatic maps in patients with secondary lymphedema. Materials and Methods This retrospective study was approved by the institutional review board. The diagnostic quality of 42 DARC MR lymphangiographic studies was compared with that of 42 conventional MR lymphangiographic studies. Two independent readers rated venous contamination as absent, mild, or moderate to severe...
September 21, 2017: Radiology
https://www.readbyqxmd.com/read/28933897/guessing-versus-misremembering-in-recognition-a-comparison-of-continuous-two-high-threshold-and-low-threshold-models
#16
Jeffrey J Starns, Qiuli Ma
The two-high-threshold (2HT) model of recognition memory assumes that people make memory errors because they fail to retrieve information from memory and make a guess, whereas the continuous unequal-variance (UV) model and the low-threshold (LT) model assume that people make memory errors because they retrieve misleading information from memory. We explored the nature of memory errors by comparing guessing and memory performance. In 2 experiments, participants studied lists of words followed by a test in which each trial was preceded by a cue indicating the probability that the trial would have a studied word...
September 21, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28933830/immobilized-cobalt-bis-benzenedithiolate-complexes-exceptionally-active-heterogeneous-electrocatalysts-for-dihydrogen-production-from-mildly-acidic-aqueous-solutions
#17
Shawn C Eady, Molly M MacInnes, Nicolai Lehnert
A series of cobalt bis(benzenedithiolate) complexes with varying benzenedithiolate (general abbreviation: bdt(2-)) ring substitutions (S2C6X4(2-)) were prepared and adsorbed on inexpensive electrodes composed of (a) reduced graphene oxide (RGO) electrodeposited on fluorine-doped tin oxide (FTO) and (b) highly ordered pyrolytic graphite (HOPG). The catalyst-adsorbed electrodes are characterized by X-ray photoelectron spectroscopy. Catalyst loading across the ligand series improved notably with increasing halide substitution [from 2...
September 21, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28933799/rivaroxaban-for-preventing-venous-thromboembolism-in-high-risk-ambulatory-patients-with-cancer-rationale-and-design-of-the-cassini-trial-rationale-and-design-of-the-cassini-trial
#18
Alok Khorana, Saroj Vadhan-Raj, Nicole M Kuderer, Ted Wun, Howard Liebman, Gerald Soff, Chandra Belani, Eileen M O'Reilly, Robert McBane, John Eikelboom, C V Damaraju, Karen Beyers, Flavia Dietrich, Ajay Kakkar, Hanno Riess, Renata D'Alpino Peixoto, Gary H Lyman
Venous thromboembolism (VTE) is a frequent complication of cancer associated with morbidity, mortality, increased hospitalizations and higher health care costs. Cancer patients at increased risk for VTE can be identified using a validated risk assessment score, and the incidence of VTE can be reduced in high-risk settings using anticoagulation. Rivaroxaban is a potent, oral, direct, factor Xa inhibitor approved for the prevention and treatment of thromboembolic events, including VTE. CASSINI is a double-blind, randomized, parallel-group, multicentre study comparing rivaroxaban with placebo in adult ambulatory patients with various cancers who are initiating systemic cancer therapy and are at high risk of VTE (Khorana score ≥ 2)...
September 21, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28933721/flexible-carbon-nanotube-modified-separator-for-high-performance-lithium-sulfur-batteries
#19
Bin Liu, Xiaomeng Wu, Shan Wang, Zhen Tang, Quanling Yang, Guo-Hua Hu, Chuanxi Xiong
Lithium-sulfur (Li-S) batteries have become promising candidates for electrical energy storage systems due to their high theoretical specific energy density, low cost and environmental friendliness. However, there are some technical obstacles of lithium-sulfur batteries to be addressed, such as the shuttle effect of polysulfides. Here, we introduced organically modified carbon nanotubes (CNTs) as a coating layer for the separator to optimize structure and enhance the performance of the Li-S battery. The results showed that the cell with a CNTs-coated separator exhibited an excellent cycling performance...
July 26, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28933714/hr-v-combining-dot-above-o2-and-rpe-relationships-in-an-aquatic-incremental-maximum-test-performed-by-young-women
#20
Gabriela B David, Luana S Andrade, Gustavo Z Schaun, Cristine L Alberton
David, GB, Andrade, LS, Schaun, GZ, and Alberton, CL. HR, V[Combining Dot Above]O2, and RPE relationships in an aquatic incremental maximum test performed by young women. J Strength Cond Res 31(10): 2852-2858, 2017-The purpose of the study was to verify the relationship between oxygen uptake (V[Combining Dot Above]O2), heart rate (HR), rate of perceived exertion (RPE), and cadence (CAD) in an aquatic incremental maximum test performed during a water-based stationary running exercise. The study also verified the best adjustments for these relationships (linear or polynomial)...
October 2017: Journal of Strength and Conditioning Research
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