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https://www.readbyqxmd.com/read/29218502/lower-preoperative-hounsfield-unit-values-are-associated-with-intra-operative-fractures-in-cementless-bipolar-hemiarthroplasty
#1
Seung-Ju Kim, Hyun-Soo Park, Dong-Woo Lee, Jong Hun Kim
The use of Hounsfield units (HU) from CT scanning to assess regional BMD has been described. Therefore, we evaluated whether HU could be used to identify osteoporosis of the proximal part of the femur. The results showed that HU assessment is associated with the presence of intra-operative fracture during arthroplasty. INTRODUCTION: The aim with this study was to determine the association of preoperative Hounsfield unit (HU) in hip computed tomography (CT) with intra-operative osteoporotic fracture during cementless hemiarthroplasty...
December 7, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29218392/unusual-circumstances-to-diagnose-cervical-pott-s-disease
#2
Mohamed Ali Kedous, Ahmed Msakni, Wael Chebbi, Mourad Zaraa, Mohsen Trabelsi
Tuberculous spondylodiscitis usually affects the dorso-lumbar spine, and its cervical location is a rare condition that can mimic other diseases and consequently cause treatment delays. We report a case of tuberculous spondylodiscitis of the lower cervical spine discovered under unusual circumstances in a patient with severe polytrauma involving a cranio-cerebral trauma, a non-displaced fracture of the two laminæ and the spinous process of the C6 vertebrae as well as fibular and tibial shaft fractures. The patient underwent static tibial nailing, and a collar with occipital and chin supports was applied...
December 7, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29216909/which-measuring-site-in-ankylosing-spondylitis-is-best-to-detect-bone-loss-and-what-predicts-the-decline-results-from-a-5-year-prospective-study
#3
Anna Deminger, Eva Klingberg, Mattias Lorentzon, Mats Geijer, Jan Göthlin, Martin Hedberg, Eva Rehnberg, Hans Carlsten, Lennart T Jacobsson, Helena Forsblad-d'Elia
BACKGROUND: Studies have shown increased prevalence of osteoporosis and increased risk for vertebral fractures in patients with ankylosing spondylitis (AS). Measurements of bone mineral density (BMD) in the lumbar spine anterior-posterior (AP) projection may be difficult to interpret due to the ligamentous calcifications, and the lateral projection might be a better measuring site. Our objectives were to investigate BMD changes after 5 years at different measuring sites in patients with AS and to evaluate disease-related variables and medications as predictors for BMD changes...
December 8, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29214508/bone-histomorphometry-in-acromegaly-patients-with-fragility-vertebral-fractures
#4
L Dalle Carbonare, V Micheletti, E Cosaro, M T Valenti, M Mottes, G Francia, M V Davì
CONTEXT: The high risk of vertebral fractures (VFs) in acromegaly patients despite normal bone mineral density (BMD) is well known. The reasons for this paradoxical finding of skeleton fragility are poorly understood due to the limited data on bone histomorphometry in acromegaly. OBJECTIVE: This study aimed to analyze histomorphometric parameters including bone microarchitecture in acromegaly patients with VFs and normal BMD compared to normal subjects, and also to evaluate the differences between active and controlled acromegaly patients...
December 6, 2017: Pituitary
https://www.readbyqxmd.com/read/29211625/anterior-inferior-iliac-spine-deformity-as-a-cause-for-extra-articular-hip-impingement-in-young-athletes-after-an-avulsion-fracture-a-case-report
#5
Eduardo N Novais, Mark F Riederer, Aaron J Provance
Extra-articular hip impingement from prior traumatic injury to the anterior inferior iliac spine (AIIS) is an uncommon cause of groin pain in young athletes. Currently, the most common treatment for this injury is arthroscopic decompression. However, hip arthroscopy is not universally available and requires advanced skills. We report 2 cases of the development of extra-articular hip impingement from unusual bony exostoses off the AIIS after traumatic injury in 2 young athletes who underwent open surgical resection...
December 1, 2017: Sports Health
https://www.readbyqxmd.com/read/29209660/mesocrystalline-calcium-silicate-hydrate-a-bioinspired-route-toward-elastic-concrete-materials
#6
Andreas Picker, Luc Nicoleau, Zaklina Burghard, Joachim Bill, Igor Zlotnikov, Christophe Labbez, André Nonat, Helmut Cölfen
Calcium silicate hydrate (C-S-H) is the binder in concrete, the most used synthetic material in the world. The main weakness of concrete is the lack of elasticity and poor flexural strength considerably limiting its potential, making reinforcing steel constructions necessary. Although the properties of C-S-H could be significantly improved in organic hybrids, the full potential of this approach could not be reached because of the random C-S-H nanoplatelet structure. Taking inspiration from a sea urchin spine with highly ordered nanoparticles in the biomineral mesocrystal, we report a bioinspired route toward a C-S-H mesocrystal with highly aligned C-S-H nanoplatelets interspaced with a polymeric binder...
November 2017: Science Advances
https://www.readbyqxmd.com/read/29209416/reliability-of-analysis-of-the-bone-mineral-density-of-the-second-and-fifth-metatarsals-using-dual-energy-x-ray-absorptiometry-dxa
#7
N Stewart Pritchard, James M Smoliga, Anh-Dung Nguyen, Micah C Branscomb, David R Sinacore, Jeffrey B Taylor, Kevin R Ford
Background: Metatarsal fractures, especially of the fifth metatarsal, are common injuries of the foot in a young athletic population, but the risk factors for this injury are not well understood. Dual-energy x-ray absorptiometry (DXA) provides reliable measures of regional bone mineral density to predict fracture risk in the hip and lumbar spine. Recently, sub-regional metatarsal reliability was established in fresh cadaveric specimens and associated with ultimate fracture force. The purpose of this study was to assess the reliability of DXA bone mineral density measurements of sub-regions of the second and fifth metatarsals in a young, active population...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29208525/novel-familial-mutation-of-lrp5-causing-high-bone-mass-genetic-analysis-clinical-presentation-and-characterization-of-bone-matrix-mineralization
#8
K M Roetzer, G Uyanik, A Brehm, J Zwerina, S Zandieh, T Czech, P Roschger, B M Misof, K Klaushofer
The Wnt signalling pathway is a critical regulator of bone mass and quality. Several heterozygous mutations in the LRP5 gene, a Wnt co-receptor, causing high bone mass (LRP5-HBM) have been described to date. The pathogenic mechanism is thought to be a gain-of-function caused by impaired inhibition of the canonical Wnt signalling pathway, thereby leading to increased bone formation. We report the cases of two affected family members, a 53-year-old mother and her 23-year-old daughter, with high bone mass (T-scores mother: lumbar spine 11...
December 5, 2017: Bone
https://www.readbyqxmd.com/read/29207490/is-trabecular-bone-score-valuable-in-bone-microstructure-assessment-after-gastric-bypass-in-women-with-morbid-obesity
#9
Agustina Pia Marengo, Fernando Guerrero Pérez, Luis San Martín, Rosa Monseny, Anna Casajoana, Rocio Valera, Nuria Virgili, Andreu Simó Servat, Albert Prats, Carmen Gómez-Vaquero, Nuria Vilarrasa
INTRODUCTION: The effects of bariatric surgery on skeletal health raise many concerns. Trabecular bone score (TBS) is obtained through the analysis of lumbar spine dual X-ray absorptiometry (DXA) images and allows an indirect assessment of skeletal microarchitecture (MA). The aim of our study was to evaluate the changes in bone mineral density (BMD) and alterations in bone microarchitecture assessed by TBS in morbidly obese women undergoing Roux-en-Y gastric bypass (RYGB), over a three-year follow-up...
December 2, 2017: Nutrients
https://www.readbyqxmd.com/read/29207223/-fragility-fracture-in-the-chronic-kidney-disease-ckd
#10
REVIEW
Maria Fusaro, Andrea Aghi, Maria Cristina Mereu, Andrea Giusti
Fragility fractures (FF) are common in patients with chronic kidney disease (CKD), and they occur at a younger age and with a higher frequency than in the general population, producing significant morbidity, mortality and healthcare costs. The pathogenic mechanisms underlying FF in CKD patients have not been completely understood. Behind CKD-MBD, the uremic toxicity should play a role in their pathogenesis, by affecting bone quality (uremic osteoporosis). There are very few prospective studies investigating risk factors for fragility fractures in CKD patients, and available algorithms for fracture risk prediction (FRAX and DeFRA) have never considered CKD...
December 5, 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/29206797/instability-of-the-hip-joint-after-posterior-acetabular-wall-fracture-independent-risk-factors-remain-elusive
#11
Jay H Patel, Berton R Moed
BACKGROUND: Exact determinants of hip instability have not been established for fractures of the posterior wall of the acetabulum involving ≤50% of the wall. Therefore, examination of the hip under anesthesia (EUA) is routinely performed. Recently, the superior exit point of the fracture has been reported to be an important identifiable risk factor. Pre-existing adult hip dysplasia (developmental dysplasia of the hip [DDH]) is thought to have a similar role. The purpose of this study was to determine if any known radiographic measurements and signs associated with DDH, or any fracture characteristics, are independent risk factors for hip instability after fracture of the posterior wall of the acetabulum...
December 6, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29204490/lumbar-chance-fracture-after-direct-anterior-total-hip-arthroplasty
#12
Michael Pitta, Corey J Wallach, Colleen Bauk, William G Hamilton
This report describes a patient with ankylosing spondylitis (AS) who underwent total hip arthroplasty (THA) by the direct anterior approach and sustained a L4-5 extension fracture dislocation with neural deficits. A magnetic resonance imaging revealed an epidural hematoma at the site of the fracture causing critical stenosis. The patient was taken to the operating room for a L3-S1 posterior decompression with L2-pelvis posterior spinal fusion. AS and diffuse idiopathic skeletal hyperostosis create a stiff spine that predisposes to fractures because of the larger moment arms experienced than normal spines...
December 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/29204193/management-and-outcome-analysis-of-pediatric-unstable-thoracolumbar-spine-injury-large-surgical-series-with-literature-review
#13
REVIEW
Guru Dutta Satyarthee, M Sangani, Sumit Sinha, Deepak Agrawal
Pediatric thoracolumbar spine fractures are considered rare injuries with paucity of publication across the globe. Further, spine injuries in children are comparatively rarer, and pediatric spine differs from adults, both biomechanically and anatomically; so, adult spine management strategy cannot be applied to pediatric cases, and exact guidelines for management of pediatric spinal injury is lacking. The current study is undertaken to study epidemiology, surgical management, and outcome of pediatric dorsolumbar unstable spine injury...
July 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29202732/sex-differences-in-response-to-targeted-kyphosis-specific-exercise-and-posture-training-in-community-dwelling-older-adults-a-randomized-controlled-trial
#14
Wendy B Katzman, Neeta Parimi, Amy Gladin, Eduard A Poltavskiy, Anne L Schafer, Roger K Long, Bo Fan, Shirley S Wong, Nancy E Lane
BACKGROUND: Hyperkyphosis, an excessive anterior curvature in the thoracic spine, is associated with reduced health status in older adults. Hyperkyphosis is highly prevalent, more common in older women than men. There is no standard intervention to reduce age-related hyperkyphosis. Sex differences in response to a kyphosis-specific exercise intervention are not known. METHODS: We conducted a randomized controlled trial of a targeted kyphosis-specific exercise and postural training program on the primary outcome Cobb angle of kyphosis, and investigated whether the magnitude of change differed between men and women...
December 4, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29201578/vertebral-compression-fractures-after-lumbar-instrumentation
#15
Michelle Granville, Aldo Berti, Robert E Jacobson
Lumbar spinal stenosis (LSS) is primarily found in an older population. This is a similar demographic group that develops both osteoporosis and vertebral compression fractures (VCF). This report reviewed a series of patients treated for VCF that had previous lumbar surgery for symptomatic spinal stenosis. Patients that only underwent laminectomy or fusion without instrumentation had a similar distribution of VCF as the non-surgical population in the mid-thoracic, or lower thoracic and upper lumbar spine. However, in the patients that had previous short-segment spinal instrumentation, fractures were found to be located more commonly in the mid-lumbar spine or sacrum adjacent to or within one or two spinal segments of the spinal instrumentation...
September 29, 2017: Curēus
https://www.readbyqxmd.com/read/29200862/association-between-serum-cystatin-c-and-bone-mineral-density-in-korean-adults
#16
Dongwon Yi, Ah Reum Khang, Hye Won Lee, Seok Man Son, Yang Ho Kang
Background: Serum cystatin C has been known as a novel marker of preclinical renal dysfunction, and higher cystatin C levels are associated with increased risks of hip and nonvertebral fractures. However, there are few reports on the association between serum cystatin C and bone mineral density (BMD), especially in the Asian population. We evaluated the association between cystatin C levels and BMD of the spine and hip in Korean adults. Methods: A cross-sectional study was performed in 865 Korean adults (325 men and 540 women) who participated in a comprehensive medical examination program and underwent bone densitometry...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29200483/biomechanical-analysis-of-range-of-motion-and-failure-characteristics-of-osteoporotic-spinal-compression-fractures-in-human-cadaver
#17
Robert F Heary, Naresh K Parvathreddy, Nitin Agarwal
Background: Vertebroplasty is a treatment for osteoporotic vertebral compression fractures. The optimal location of needle placement for cement injection remains a topic of debate. As such, the authors assessed the effects of location of two types of cement instillations. In addition, the motion and failure modes at the index and adjacent segments were measured. Materials and Methods: Seven human osteoporotic cadaver spines (T1-L4), cut into four consecutive vertebral segments, were utilized...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29200479/management-of-sub-axial-cervical-spine-injuries
#18
Gautam Zaveri, Gurdip Das
Sub-axial cervical spine injuries are commonly seen in patients with blunt trauma. They may be associated with spinal cord injury resulting in tetraplegia and severe permanent disability. Immobilization of the neck, maintenance of blood pressure and oxygenation, rapid clinical and radiological assessment of all injuries, and realignment of the spinal column are the key steps in the emergency management of these injuries. The role of intravenous methylprednisolone administration in acute spinal cord injuries remains controversial...
November 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29196764/differences-in-trabecular-microarchitecture-and-simplified-boundary-conditions-limit-the-accuracy-of-qct-based-finite-element-models-of-vertebral-failure
#19
Amira I Hussein, Daniel Louzeiro, Ginu U Unnikrishnan, Elise F Morgan
Vertebral fractures are common in the elderly, but efforts to reduce their incidence have been hampered by incomplete understanding of the failure processes that are involved. This study's goal was to elucidate failure processes in the lumbar vertebra and to assess the accuracy of quantitative computed tomography (QCT)-based finite element (FE) simulations of these processes. Following QCT scanning, spine segments (n=27) consisting of L1 with adjacent intervertebral discs and neighboring endplates of T12 and L2 were compressed axially in a stepwise manner...
December 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29195740/validation-of-fragility-fractures-in-primary-care-electronic-medical-records-a-population-based-study
#20
Daniel Martinez-Laguna, Alberto Soria-Castro, Cristina Carbonell-Abella, Pilar Orozco-López, Pilar Estrada-Laza, Xavier Nogues, Adolfo Díez-Perez, Daniel Prieto-Alhambra
PURPOSE: Electronic medical records databases use pre-specified lists of diagnostic codes to identify fractures. These codes, however, are not specific enough to disentangle traumatic from fragility-related fractures. We report on the proportion of fragility fractures identified in a random sample of coded fractures in SIDIAP. METHODS: Patients≥50 years old with any fracture recorded in 2012 (as per pre-specified ICD-10 codes) and alive at the time of recruitment were eligible for this retrospective observational study in 6 primary care centres contributing to the SIDIAP database (www...
November 28, 2017: Reumatología Clinica
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