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https://www.readbyqxmd.com/read/29776620/physical-neighborhood-and-social-environment-beliefs-about-sleep-sleep-hygiene-behaviors-and-sleep-quality-among-african-americans
#1
Soohyun Nam, Robin Whittemore, Sunyoung Jung, Carl Latkin, Trace Kershaw, Nancy S Redeker
OBJECTIVES: African Americans (AAs) have a higher prevalence of sleep disorders than other racial/ethnic groups. However, little is known about the relationships among individual and neighborhood factors related to sleep quality in AAs. The purposes of this study were to (1) describe beliefs about sleep, sleep hygiene behaviors, and sleep quality among AAs; and (2) examine the relationships among sociodemographic characteristics, neighborhood environment, beliefs about sleep, sleep hygiene behaviors, and sleep quality...
June 2018: Sleep Health
https://www.readbyqxmd.com/read/29773773/cuban-epidemic-neuropathy-insights-into-the-toxic-nutritional-hypothesis-through-international-collaboration
#2
Alina González-Quevedo, Rosaralis Santiesteban-Freixas, Janis T Eells, Lucimey Lima, Alfredo A Sadun
From 1991 to 1993, an epidemic of optic and peripheral neuropathy-the largest of the century-broke out in Cuba, affecting more than 50,000 people. Initially the main clinical features were decreased visual acuity, central and cecocentral scotomas, impaired color vision and absence of the papillomacular bundle. Later, peripheral and mixed optic-peripheral forms began to appear. Due to the magnitude of the epidemic, the Cuban government requested help from the international community at the 46th World Health Assembly in 1993...
April 2018: MEDICC Review
https://www.readbyqxmd.com/read/29773175/blood-lead-and-cadmium-in-age-related-macular-degeneration-in-a-turkish-urban-population
#3
Elif Damar Güngör, Fatma Yülek, Utku Serkant, Yasin Toklu, Asım Hocaoğlu, Şaban Şimsek
PURPOSE: To evaluate the blood lead (Pb) and cadmium (Cd) levels in age related macular degeneration (AMD) in a turkish urban population. METHODS: Blood Pb and Cd levels of 31 AMD patients and 24 age and gender matched controls with no sign of AMD were measured using dual atomic absorption spectrophotometer system (AAS). History of hypertension, diabetes mellitus, cigarette smoking, myocardial infarction and stroke were obtained from all subjects. Degree of AMD was grade 4 according to the Age-Related Eye Disease Study grading system...
July 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29770450/relationship-of-epitope-glycosylation-and-other-properties-of-blood-group-proteins-to-the-immunogenicity-of-blood-group-antigens
#4
John G Howe, Gary Stack
BACKGROUND: The intrinsic properties of polypeptide blood group antigens that determine their relative immunogenicities are unknown. Because size, composition, charge, dose, and epitope glycosylation affect the immunogenicity of other polypeptides, we examined whether similar properties were related to the immunogenicity of blood group antigens. STUDY DESIGN AND METHODS: Amino acid (AA) sequences of antithetical blood group antigens were searched for N- and O-glycosylation sites...
May 16, 2018: Transfusion
https://www.readbyqxmd.com/read/29769214/tumor-infiltrating-lymphocytes-and-colorectal-cancer-survival-in-african-american-and-caucasian-patients
#5
Kristin Wallace, David N Lewin, Shaoli Sun, Clayton M Spiceland, Don C Rockey, Alexander V Alekseyenko, Jennifer D Wu, John A Baron, Anthony J Alberg, Elizabeth G Hill
BACKGROUND: Compared with Caucasian Americans (CAs), African Americans (AAs) with colorectal cancer (CRC) have poorer survival, especially younger age patients. A robust lymphocytic reaction within CRCs is strongly associated with better survival but whether immune response impacts the disparity in CRC survival is not known. METHODS: The study population was comprised of 211 histologically confirmed CRCs at the Medical University of South Carolina (159 CAs, 52 AAs) diagnosed between 01/01/2000 and 06/30/2013...
May 16, 2018: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29769004/regulatory-role-of-amino-acids-in-pigs-fed-on-protein-restricted-diets
#6
Sung Woo Kim, Hongyu Chen, Wanpuech Parnsen
The high inclusion of dietary protein and the imbalance of amino acid (AA) composition in animal husbandry result in inefficient utilization of protein resources and increased nitrogen excretion. Therefore, an efficient approach to alleviate the nitrogen excretion and increase the utilization of protein resources is to formulate the AA-balance protein-restricted diet with crystalline AA supplementation. Nowadays, it is essential to thoroughly understand the regulatory mechanisms of AAs on body metabolism and their vital roles in protein-restricted diets...
May 16, 2018: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/29768930/a-strategic-planning-tool-for-increasing-african-american-blood-donation
#7
Ashley Singleton, Regena Spratling
Historically, African Americans (AAs) have been underrepresented as blood donors. Having a lack of racially diverse blood donors contributes to transfusion complications, particularly in patients with sickle cell disease, who are both disproportionately AA and the recipients of frequent transfusions. Increasing AA blood donation is a complex public health issue. This review article serves to fill a gap in translating research regarding known hindrances and facilitators of AA blood donation to improve real-world donation practice and ultimately, patient outcomes...
May 1, 2018: Health Promotion Practice
https://www.readbyqxmd.com/read/29766366/consensus-statement-on-the-definition-of-neurogenic-supine-hypertension-in-cardiovascular-autonomic-failure-by-the-american-autonomic-society-aas-and-the-european-federation-of-autonomic-societies-efas-endorsed-by-the-european-academy-of-neurology-ean-and-the
#8
REVIEW
Alessandra Fanciulli, Jens Jordan, Italo Biaggioni, Giovanna Calandra-Buonaura, William P Cheshire, Pietro Cortelli, Sabine Eschlboeck, Guido Grassi, Max J Hilz, Horacio Kaufmann, Heinz Lahrmann, Giuseppe Mancia, Gert Mayer, Lucy Norcliffe-Kaufmann, Anne Pavy-Le Traon, Satish R Raj, David Robertson, Isabel Rocha, Walter Struhal, Roland Thijs, Konstantinos P Tsioufis, J Gert van Dijk, Gregor K Wenning
PURPOSE: Patients suffering from cardiovascular autonomic failure often develop neurogenic supine hypertension (nSH), i.e., high blood pressure (BP) in the supine position, which falls in the upright position owing to impaired autonomic regulation. A committee was formed to reach consensus among experts on the definition and diagnosis of nSH in the context of cardiovascular autonomic failure. METHODS: As a first and preparatory step, a systematic search of PubMed-indexed literature on nSH up to January 2017 was performed...
May 15, 2018: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29764929/scaffolding-our-systems-patients-and-families-reaching-in-as-a-source-of-healthcare-resilience
#9
Jane K O'Hara, Karina Aase, Justin Waring
No abstract text is available yet for this article.
May 15, 2018: BMJ Quality & Safety
https://www.readbyqxmd.com/read/29759540/incidence-predictors-and-outcomes-of-early-atrial-arrhythmias-after-lung-transplant-a-systematic-review-and-meta-analysis
#10
Marwan Saad, Islam Y Elgendy, Amgad Mentias, Hesham K Abdelaziz, Amr F Barakat, Ahmed Abuzaid, Akram Y Elgendy, Mohammad K Mojadidi, Satish Chandrashekaran, Ahmed N Mahmoud
OBJECTIVES: This study sought to determine the incidence, predictors, and prognostic implications of early post-lung transplant atrial arrhythmias (AAs). BACKGROUND: Although frequently encountered, the prognostic implications of early AAs after lung transplant remain uncertain. METHODS: A systematic review of MEDLINE and the Cochrane Library was conducted for all studies that reported early post-lung transplant AAs. Random-effects DerSimonian-Laird risk ratios (RRs) were calculated for categorical variables and standardized mean difference (SMD) for continuous variables...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29758310/chemical-synthesis-and-characterization-of-chitosan-silver-nanocomposites-films-and-their-potential-antibacterial-activity
#11
Aamna Shah, Izhar Hussain, Ghulam Murtaza
This study provides the optimum preparation parameters for functional chitosan silver nanocomposite (CSN) films with promising antibacterial efficacy though prepared with very low silver nitrate (AgNO3 ) concentration. Chitosan nano‑silver composites were fabricated by In-situ chemical method utilizing the reducing ability of sodium borohydride (NaBH4 ) and afterward casted into films. Utilization of response surface methodology, NCSS, and SigmaPlot for the optimization of CSN and their predicted antibacterial efficacy assessment of the selected bacterial strains (standard and clinical) was the essential part of the study...
May 11, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29756571/the-mechanism-of-dietary-protein-modulation-of-bone-metabolism-via-alterations-in-members-of-the-gh-igf-axis
#12
Chen Lv, Songcai Liu, Jichao Xia, Lei Xu, Yunyun Cheng, Wenyue Li, Yu Zhang, Gang Wang, Wenzhen Wei, Hongyu Shi, Shan Huang, Nan Wang, Linlin Hao
Dietary protein intake as a critical regulatory factor of bone metabolism is a vital element to regulate nutritional status of mammals. Under the action of protease, dietary protein is digested into peptides and free amino acids (FAAs). Then, the metabolites are absorbed by enterocytes and metabolized in various organs of mammals. The dietary protein intake regulates bone metabolism generally via two aspects, dietary itself and signaling transduction. At the dietary level, different kinds of amino acids (AAs) of dietary protein may affect various protein metabolism of bone by regulating proteasome depending on proteolysis and protein synthesis...
May 14, 2018: Current Protein & Peptide Science
https://www.readbyqxmd.com/read/29755393/language-lateralization-and-auditory-attention-impairment-in-young-adults-at-ultra-high-risk-for-psychosis-a-dichotic-listening-study
#13
Ingvild Aase, Kristiina Kompus, Jens Gisselgård, Inge Joa, Jan O Johannessen, Kolbjørn Brønnick
Objectives: Impaired attention and language functions are common in psychosis, but have been less explored in subjects with ultra-high risk for psychosis (UHR). The aim of the study was to investigate differences in language lateralization and auditory attention in UHR subjects compared to healthy controls with a dichotic listening paradigm. In addition, symptoms from The Structural Interview for Prodromal Syndromes (SIPS) were explored in relation to performance on dichotic listening. Methods: The UHR subjects ( n = 46, female = 28, mean age = 17...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29753144/isolation-of-an-invertebrate-type-lysozyme-from-the-nephridia-of-the-echiura-urechis-unicinctus-and-its-recombinant-production-and-activities
#14
Hye Young Oh, Chan-Hee Kim, Hye-Jin Go, Nam Gyu Park
Invertebrates, unlike vertebrates which have adaptive immune system, rely heavily on the innate immune system for the defense against pathogenic bacteria. Lysozymes, along with other immune effectors, are regarded as an important group in this defense. An invertebrate-type (i-type) lysozyme, designated Urechis unicinctus invertebrate-type lysozyme, Uu-ilys, has been isolated from nephridia of Urechis unicinctus using a series of high performance liquid chromatography (HPLC), and ultrasensitive radial diffusion assay (URDA) as a bioassay system...
May 9, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29752851/idh-mutated-astrocytomas-with-19q-loss-constitute-a-subgroup-that-confers-better-prognosis
#15
Ryohei Otani, Takeo Uzuka, Fumi Higuchi, Hadzki Matsuda, Masashi Nomura, Shota Tanaka, Akitake Mukasa, Koichi Ichimura, Phyo Kim, Keisuke Ueki
IDH-mutant gliomas are classified into astrocytic or oligodendroglial tumors by 1p/19q status in WHO 2016 classification, with the latter presenting with characteristic morphology and better prognosis in general. However, the morphological and genetic features within each category are varied, and there may be distinguishable subtypes. We analyzed 170 WHO grade II to IV gliomas resected in our institution. 1p/19q status was analyzed by microsatellite analysis, and genetic mutations were analyzed by next-generation sequencing and Sanger sequencing...
May 12, 2018: Cancer Science
https://www.readbyqxmd.com/read/29752577/flexible-sigmoidoscopy-in-colorectal-cancer-screening-implications-of-different-colonoscopy-referral-strategies
#16
Tobias Niedermaier, Korbinian Weigl, Michael Hoffmeister, Hermann Brenner
Flexible sigmoidoscopy (FS) screening reduces colorectal cancer incidence and mortality. Its potential to detect proximal neoplasms depends on colonoscopy referral. We estimated diagnostic performance of sigmoidoscopy using 12 different referral criteria in detecting colorectal cancer and advanced adenomas. Colonoscopy results from 14,947 participants of screening colonoscopy in Germany were used to derive sensitivity of sigmoidoscopy for colorectal cancer, advanced adenomas (AAs), and any advanced neoplasms in the proximal colon...
May 12, 2018: European Journal of Epidemiology
https://www.readbyqxmd.com/read/29746791/preferential-accumulation-of-inorganic-elements-in-amanita-muscaria-from-north-eastern-poland
#17
Krzysztof Lipka, Martyna Saba, Jerzy Falandysz
Concentrations of Al, Ba, Cd, Ca, Co, Cu, Fe, K, Mg, Mn, Hg, Rb, Ag, Na, Sr and Zn were analysed in fruiting bodies of A. muscaria. This mushroom is considered conditionally edible, since parboiling can detoxify its fruiting bodies from the hallucinogens and render it edible. The specific purpose of the research is the little-known phenomenon of the variability of mineral composition of mushrooms for generations harvested in the same forest areas - both in terms of their nutritional value and anthropogenic influences...
May 10, 2018: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/29746700/%C3%AE-2-adrenergic-receptor-autoantibodies-alleviated-myocardial-damage-induced-by-%C3%AE-1-adrenergic-receptor-autoantibodies
#18
Ning Cao, Hao Chen, Yan Bai, Xiaochun Yang, Wenli Xu, Weiwei Hao, Yi Zhou, Jiayin Chai, Ye Wu, Zhaojia Wang, Xiaochen Yin, Li Wang, Wen Wang, Huirong Liu, Michael L X Fu
Aims: β1-adrenergic receptor autoantibodies (β1-AAs) and β2-adrenergic receptor autoantibodies (β2-AAs) are present in patients with heart failure (HF); however, their interrelationship with cardiac structure and function remains unknown. This study explored the effects of the imbalance between β1-AAs and β2-AAs on cardiac structure and its underlying mechanisms in HF. Methods and Results: Patients with left systolic HF who suffered from coronary heart disease (65...
May 8, 2018: Cardiovascular Research
https://www.readbyqxmd.com/read/29745724/radiosensitivity-and-transgenerational-effects-in-non-human-species
#19
C Adam-Guillermin, T Hertal-Aas, D Oughton, L Blanchard, F Alonzo, O Armant, N Horemans
The ALLIANCE working group on effects of ionising radiation on wildlife brings together European researchers to work on the topics of radiosensitivity and transgenerational effects in non-human biota. Differences in radiation sensitivity across species and phyla are poorly understood, but have important implications for understanding the overall effects of radiation and for radiation protection; for example, sensitive species may require special attention in monitoring and radiation protection, and differences in sensitivity between species also lead to overall effects at higher levels (community, ecosystem), since interactions between species can be altered...
January 1, 2018: Annals of the ICRP
https://www.readbyqxmd.com/read/29743941/cost-effectiveness-of-dialectical-behaviour-therapy-vs-enhanced-usual-care-in-the-treatment-of-adolescents-with-self-harm
#20
Egil Haga, Eline Aas, Berit Grøholt, Anita J Tørmoen, Lars Mehlum
Background: Studies have shown that dialectical behaviour therapy (DBT) is effective in reducing self-harm in adults and adolescents. Aims: To evaluate the cost-effectiveness of DBT for adolescents (DBT-A) compared to enhanced usual care (EUC). Methods: In a randomised study, 77 adolescents with repeated self-harm were allocated to 19 weeks of outpatient treatment, either DBT-A ( n  = 39) or EUC ( n  = 38). Cost-effective analyses, including estimation of incremental cost-effectiveness ratios, were conducted with self-harm and global functioning (CGAS) as health outcomes...
2018: Child and Adolescent Psychiatry and Mental Health
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