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https://www.readbyqxmd.com/read/28724317/who-among-patients-with-acquired-brain-injury-returned-to-work-after-occupational-rehabilitation-the-rapid-return-to-work-cohort-study
#1
Randi Wågø Aas, Lise Aasen Haveraaen, Evelien P M Brouwers, Lisebet Skeie Skarpaas
BACKGROUND: Acquired brain injury (ABI) is known to be severely disabling. On average, 40% of employees return to work (RTW) within two years after injury. There is, however, limited research on what might contribute to successful RTW. AIM: To examine factors that might impact the time-to first RTW for patients with ABI, participating in a RTW-program. METHODS: The study was designed as a cohort study of patients on sick leave due to mild or moderate ABI (n = 137)...
July 20, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28721399/nutritional-and-functional-properties-of-fishmeal-produced-from-fresh-by-products-of-cod-gadus-morhua-l-and-saithe-pollachius-virens
#2
Ola Ween, Janne K Stangeland, Turid S Fylling, Grete Hansen Aas
Fresh by-products of whitefish such as cod and saithe is processed to fishmeal (FM) on-board seagoing Norwegian trawlers. The aim of this study was to document the properties of whitefish FM (WFM) protein with respect to, physicochemical and bioactive properties. Analysis of the proximate composition of representative seasonal WFM batches show that the production is robust without much variance. The mean protein (61.9 ± 1.2), fat (8.9 ± 1.1%), moisture (5 ± 1.2%) and ash content (22.4 ± 0.8%), reflect the use of lean and bony raw-material...
July 2017: Heliyon
https://www.readbyqxmd.com/read/28719635/differential-protein-expression-profile-in-the-hypothalamic-gt1-7-cell-line-after-exposure-to-anabolic-androgenic-steroids
#3
Freddyson J Martínez-Rivera, Juliana Pérez-Laspiur, María E Santiago-Gascot, Abner G Alemán-Reyes, Emanuel García-Santiago, Yolanda Rodríguez-Pérez, Cristhian Calo-Guadalupe, Inelia Otero-Pagán, Roxsana N Ayala-Pagán, Magdiel Martínez, Yisel M Cantres-Rosario, Loyda M Meléndez, Jennifer L Barreto-Estrada
The abuse of anabolic androgenic steroids (AAS) has been considered a major public health problem during decades. Supraphysiological doses of AAS may lead to a variety of neuroendocrine problems. Precisely, the hypothalamic-pituitary-gonadal (HPG) axis is one of the body systems that is mainly influenced by steroidal hormones. Fluctuations of the hormonal milieu result in alterations of reproductive function, which are made through changes in hypothalamic neurons expressing gonadotropin-releasing hormone (GnRH)...
2017: PloS One
https://www.readbyqxmd.com/read/28718924/preliminary-study-of-a-novel-puborectalis-like-artificial-anal-sphincter
#4
Wentian Jin, Guozheng Yan, Hao Wu, Shan Lu, Zerun Zhou
Artificial anal sphincter (AAS) is an in situ implanted device that acts as a treatment for fecal incontinence regardless of etiology by augmenting the incompetent sphincteric structures. However, AAS is impeded from becoming a valid therapy by its high rate of ischemic complication and malfunction. This article presents an original puborectalis-like artificial anal sphincter (PAAS) that features a low risk of ischemia necrosis and rectal perception remodeling. The device retains continence by reproducing the action, including the pulling and angulating the rectum, of the puborectalis muscle, which forms the anorectal angle and reduces the required clamping pressure...
July 18, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28715450/african-genetic-ancestry-interacts-with-body-mass-index-to-modify-risk-for-uterine-fibroids
#5
Ayush Giri, Todd L Edwards, Katherine E Hartmann, Eric S Torstenson, Melissa Wellons, Pamela J Schreiner, Digna R Velez Edwards
Race, specifically African ancestry, and obesity are important risk factors for uterine fibroids, and likely interact to provide the right conditions for fibroid growth. However, existing studies largely focus on the main-effects rather than their interaction. Here, we firstly provide evidence for interaction between categories of body mass index (BMI) and reported-race in relation to uterine fibroids. We then investigate whether the association between inferred local European ancestry and fibroid risk is modified by BMI in African American (AA) women in the Vanderbilt University Medical Center bio-repository (BioVU) (539 cases and 794 controls) and the Coronary Artery Risk Development in Young Adults study (CARDIA, 264 cases and 173 controls)...
July 17, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28712954/social-media-platforms-and-heart-failure
#6
R Jay Widmer, Makala K Arce, Lee A Aase, Farris K Timimi
With the pervasive use of the internet and social media, the potential applicability toward patients with heart failure (HF) remains understudied. Here, we outline the general use of social media and some early work utilizing social media as well as data from our own Mayo Clinic Center for Social Media experience. Both enterprise-wide social media data as well as those specific to HF-related pages and posts appear to support the preferential use of Facebook and YouTube for potential benefit in patients with HF...
July 13, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28711608/do-anabolic-androgenic-steroids-have-performance-enhancing-effects-in-female-athletes
#7
REVIEW
Grace Huang, Shehzad Basaria
Doping with anabolic androgenic steroids (AAS) is common among both male and female athletes and is a growing public health problem. Review of historical data of systematic state-sponsored doping programs implemented by the German Democratic Republic in elite female athletes and from the clinical trials of testosterone administration in non-athlete women suggests that AAS have ergogenic effects in women. The use of AAS in female athletes has been associated with adverse effects that include acne, hirsutism, deepening of the voice and menstrual disturbances; life-threatening adverse effects such as cardiac arrhythmias and sudden death have also been reported...
July 12, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28710928/synthesis-and-characterization-of-cobalt-supported-catalysts-on-modified-magnetic-nanoparticle-green-and-highly-efficient-heterogeneous-nanocatalyst-for-selective-oxidation-of-ethylbenzene-cyclohexene-and-oximes-with-molecular-oxygen
#8
Ali Reza Faraji, Sima Mosazadeh, Fatemeh Ashouri
In this study, a new supported cobalt nanocatalyst has been described. The Fe3O4 magnetic nanoparticles (Fe3O4 MNPs) modified by SiO2/aminopropyl trimethoxy silane/cyanuric chloride (Fe3O4@SiO2-APTMS/CC) utilized for anchoring metformin-cobalt complex (Fe3O4 Ms@SiO2-APTMS/CC/Met@Co(II)). The structure of novel complex well defined by elemental analysis, ICP, AAS, BET, FT-IR, EDX, SEM, TEM, DLS, XRD, TG-DTG, VSM and XPS. The catalytic efficiency of the synthesized cobalt nanocatalyst was studied in the oxidation of ethylbenzene (EB), cyclohexene (CYHE) and various oximes using molecular oxygen as ecofriendly oxidant and high catalytic activity and selectivity toward oxidation is observed...
June 30, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28710510/surgical-reconstruction-is-a-cost-efficient-treatment-option-for-isolated-pcl-injuries
#9
Christian Owesen, Eline Aas, Asbjørn Årøen
PURPOSE AND HYPOTHESIS: The main purpose of the study is to put focus on the costs related to treating posterior cruciate ligament (PCL) injuries and the possible implications of chosen treatment strategy to the respective institutions and society. METHODS: Costs of treating PCL injuries nonoperatively and for both single-bundle (SB) and double-bundle (DB) reconstruction were estimated. These costs were translated into equivalent quality-adjusted life years (QALY) given a threshold value of Euro (€) 70,000 per QALY...
July 14, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28696790/competitive-inhibition-of-amino-acid-transport-in-human-preovulatory-ovarian-follicles
#10
Maciej Jóźwik, Marcin Jóźwik, Anna Justyna Milewska, Frederick C Battaglia, Michał Jóźwik
To date we have yet to examine whether amino acid (AA) transport in human ovarian follicles is affected by competitive inhibition. In contrast, transplacental transfer of AAs in late-gestation sheep is characterized by reciprocal competition. This phenomenon has been described by algebraic equations of umbilical uptake of AAs based on maternal arterial concentrations. In the present translational study at a university teaching hospital, we verified whether these equations apply to the transport of AAs from blood to follicular fluid (FF) in human preovulatory follicles...
July 11, 2017: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/28694662/naturally-occurring-mutations-in-the-reverse-transcriptase-region-of-hepatitis-b-virus-polymerase-from-treatment-na%C3%A3-ve-korean-patients-infected-with-genotype-c2
#11
Ji-Eun Kim, So-Young Lee, Hong Kim, Ki-Jeong Kim, Won-Hyeok Choe, Bum-Joon Kim
AIM: To report naturally occurring mutations in the reverse transcriptase region (RT) of hepatitis B virus (HBV) polymerase from treatment naïve Korean chronic patients infected with genotype C2. METHODS: Here, full-length HBV reverse transcriptase RT sequences were amplified and sequenced from 131 treatment naïve Korean patients chronically infected with hepatitis B genotype C2. The patients had two distinct clinical statuses: 59 patients with chronic hepatitis (CH) and 72 patients with hepatocellular carcinoma (HCC)...
June 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28687978/two-new-leptographium-spp-reveal-an-emerging-complex-of-hardwood-infecting-species-in-the-ophiostomatales
#12
Robert Jankowiak, Beata Strzałka, Piotr Bilański, Riikka Linnakoski, Truls Aas, Halvor Solheim, Małgorzata Groszek, Z Wilhelm de Beer
Species of Leptographium are generally characterized by mononematous conidiophores and are commonly associated with bark beetles and weevils. These species are responsible for sapstain and in some cases serious diseases on a range of primarily coniferous trees. In comparison with coniferous trees, the occurrence of Leptographium species on hardwood trees has been poorly studied in Europe. During a survey of ophiostomatoid fungi on various tree species in Norway and Poland, three unusual species, which fit the broader morphological description of Leptographium spp...
July 7, 2017: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/28684110/the-association-for-academic-surgeons-2001-2010-a-decade-of-inclusiveness
#13
Daniel I Chu, Herbert Chen
The Association for Academic Surgery (AAS) was established to inspire and develop academic surgeons. Since its founding in 1966, each decade has been marked by continued growth and innovations. The era of 2001-2010 was a decade notable for its focus on inclusiveness and diversity. In those ten years, the AAS grew its membership from all surgical backgrounds, established defining programs that remain today, and invested substantially in international outreach. In this article, we review these historical highlights and will demonstrate that the AAS remains the most important home for the young academic surgeon...
July 3, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28681286/bioremoval-of-arsenic-v-from-aqueous-solutions-by-chemically-modified-fungal-biomass
#14
J F Cárdenas-González, I Acosta-Rodríguez, Y Téran-Figueroa, A S Rodríguez-Pérez
The biosorption of arsenic (V) on nine chemically modified biomasses (with iron oxide coated) of mycelia fungi: Aspergillus flavus III, IV and V, Aspergillus fumigatus I-II, Paecilomyces sp., Cladosporium sp., Mucor sp-1 and 2 was studied in this work. This study provides evidence that the biomasses of the fungi A. flavus, IV, III and V, Paecilomyces sp., and A. fumigatus I were very efficient at removing 1 mg/L of the metal in solution, using atomic absorption spectroscopy (AAS), achieving the following percentage of removals: 97...
July 2017: 3 Biotech
https://www.readbyqxmd.com/read/28673960/helpful-strategies-for-gps-seeing-patients-with-medically-unexplained-physical-symptoms-a-focus-group-study
#15
Aase Aamland, Anette Fosse, Eline Ree, Eirik Abildsnes, Kirsti Malterud
BACKGROUND: Patients with long-lasting and disabling medically unexplained physical symptoms (MUPS) are common in general practice. GPs have previously described the challenges regarding management and treatment of patients with MUPS. AIM: To explore GPs' experiences of the strategies perceived as helpful when seeing patients with MUPS. DESIGN AND SETTING: Three focus group interviews with a purposive sample of 24 experienced GPs were held in southern Norway...
July 3, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28672100/warfarin-pharmacogenomics-in-diverse-populations
#16
Justin B Kaye, Lauren E Schultz, Heidi E Steiner, Rick A Kittles, Larisa H Cavallari, Jason H Karnes
Genotype-guided warfarin dosing algorithms are a rational approach to optimize warfarin dosing and potentially reduce adverse drug events. Diverse populations, such as African-Americans (AAs) and Latinos, have greater variability in warfarin dose requirements and are at greater risk for experiencing warfarin-related adverse events compared with individuals of European ancestry. Although these data suggest that patients of diverse populations may benefit from improved warfarin dose estimation, the vast majority of literature on genotype-guided warfarin dosing, including data from prospective randomized trials, is in populations of European ancestry...
July 3, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28671032/measuring-the-operative-treatment-effect-in-end-stage-ankle-arthritis-are-we-asking-the-right-questions-a-cofas-multicenter-study
#17
Kevin J Wing, Nuria Chapinal, Marcus P Coe, Timothy R Daniels, Mark Glazebrook, Peter Dryden, Alastair Younger, Murray J Penner, Jason M Sutherland
BACKGROUND: Foot and ankle surgeons are increasingly relying on patient-reported outcome measures (PROMs) such as the Ankle Osteoarthritis Scale (AOS) to evaluate treatment options. The objectives of this retrospective cohort study were 2-fold: (1) to examine the AOS instrument using psychometric analysis and (2) to revise the questions on the AOS to improve the effect of questions on the score and remove redundancies. METHODS: Pre- and postoperative patient scores were obtained from AOS questionnaires in the COFAS Prospective Ankle Reconstruction Database, a cohort of patients operatively treated for end-stage ankle arthritis...
June 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28670201/-teamwork-in-hospitals-a-quasi-experimental-study-protocol-applying-a-human-factors-approach
#18
Randi Ballangrud, Sissel Eikeland Husebø, Karina Aase, Oddveig Reiersdal Aaberg, Anne Vifladt, Geir Vegard Berg, Marie Louise Hall-Lord
BACKGROUND: Effective teamwork and sufficient communication are critical components essential to patient safety in today's specialized and complex healthcare services. Team training is important for an improved efficiency in inter-professional teamwork within hospitals, however the scientific rigor of studies must be strengthen and more research is required to compare studies across samples, settings and countries. The aims of the study are to translate and validate teamwork questionnaires and investigate healthcare personnel's perception of teamwork in hospitals (Part 1)...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28666393/who-initiates-and-organises-situations-for-work-related-alcohol-use-the-wirus-culture-study
#19
Kristin Nordaune, Lisebet S Skarpaas, Hildegunn Sagvaag, Lise Haveraaen, Silje Rimstad, Liv G Kinn, Randi W Aas
AIMS: Alcohol is one of the leading causes of ill health and premature death in the world. Several studies indicate that working life might influence employees' alcohol consumption and drinking patterns. The aim of this study was to explore work-related drinking situations, with a special focus on answering who initiates and organises these situations. METHODS: Data were collected through semi-structured group interviews in six Norwegian companies from the private ( n=4) and public sectors ( n=2), employing a total of 3850 employees...
June 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/28665254/alcohol-habits-and-health-care-use-in-patients-with-psychiatric-disorders
#20
Christina Nehlin, Hans Arinell, Johan Dyster-Aas, Kari Jess
OBJECTIVE: It is more common for persons with psychiatric disorders to also have alcohol problems. Studies in the general population as well as in clinical samples have found hazardous or harmful alcohol habits to be particularly prevalent in the presence of psychiatric disorders. This study sought to explore the relationships between drinking habits and health care utilization (psychiatric as well as general medical) in persons seeking psychiatric treatment and to investigate the associations between age, sex and type or number of diagnoses and health care use and costs...
June 30, 2017: Journal of Dual Diagnosis
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