Janice Chew-Harris, Chris Frampton, Charlotte Greer, Sarah Appleby, John W Pickering, Win Sen Kuan, Irwani Ibrahim, Siew Pang Chan, Zisheng Li, Oi Wah Liew, Philip D Adamson, Richard Troughton, Li Ling Tan, Weiqin Lin, Shirley Beng Suat Ooi, A Mark Richards, Christopher J Pemberton
AIMS: The performance of circulating soluble urokinase plasminogen activator receptor (suPAR) for predicting the composite endpoint of subsequent heart failure (HF) hospitalisation and/or death at 1 year was assessed in (i) patients with undifferentiated breathlessness, and generalisability was compared in (ii) disparate Western versus Asian sub-cohorts, and in (iii) the sub-cohort adjudicated with HF. METHODS AND RESULTS: Patients with acute breathlessness were recruited from the emergency departments in New Zealand (NZ, n = 612) and Singapore (n = 483)...
April 19, 2024: International Journal of Cardiology