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Vascular imaging

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https://www.readbyqxmd.com/read/28227867/knife-edge-scanning-microscopy-for-in-silico-study-of-cerebral-blood-flow-from-biological-imaging-data-to-flow-simulations
#1
Michael R Nowak, Alexander Lozovskiy, Dimitri Dobroskok, Yoonsuck Choe, Michael R Nowak, Alexander Lozovskiy, Dimitri Dobroskok, Yoonsuck Choe, Dimitri Dobroskok, Michael R Nowak, Alexander Lozovskiy, Yoonsuck Choe
Knife-edge scanning microscopy provides the capability to image whole-brain cerebral microvasculature of small organisms, such as mice, at sub-micron resolution, providing a feasible foundation for the reconstruction of circulatory pathways from the systemic to cellular scale. In this paper, we illustrate the feasibility of using this data to model cerebral blood flow using numerical simulations. Starting with a small vascular element in microcirculation of interest, we present its segmentation from the imaging-data volume, construction of its triangular surface mesh, assembly of its tetrahedral volumetric mesh from the surface, and then conclude with Stokes flow simulation of plasma through the microvascular vessel...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227865/a-dce-mri-imaging-based-model-for-simulation-of-vascular-tumour-growth
#2
Thais Roque, Veerle Kersemans, Sean Smart, Danny Allen, Julia A Schnabel, Michael Chappell, Thais Roque, Veerle Kersemans, Sean Smart, Danny Allen, Julia A Schnabel, Michael Chappell, Sean Smart, Michael Chappell, Veerle Kersemans, Danny Allen, Julia A Schnabel, Thais Roque
Imaging-based modelling of tumour growth can serve as a powerful tool to understand and predict tumour evolution and its response to therapy. The purpose of this study was to introduce, calibrate and evaluate a multi-scale model of vascular tumour growth. The model allows for proliferation, death and spatial spread of tumour cells as well as for new vessel creation. Both the calibration and the evaluation of the tumour growth model were performed using pre-clinical longitudinal time series of dynamic contrast-enhanced magnetic resonance imaging of colon carcinoma...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227856/multiquadric-spline-based-interactive-segmentation-of-vascular-networks
#3
Sachin Meena, V B Surya Prasath, Yasmin M Kassim, Richard J Maude, Olga V Glinskii, Vladislav V Glinsky, Virginia H Huxley, Kannappan Palaniappan, Sachin Meena, V B Surya Prasath, Yasmin M Kassim, Richard J Maude, Olga V Glinskii, Vladislav V Glinsky, Virginia H Huxley, Kannappan Palaniappan, Virginia H Huxley, Yasmin M Kassim, Sachin Meena, Kannappan Palaniappan, Vladislav V Glinsky, Olga V Glinskii, Richard J Maude, V B Surya Prasath
Commonly used drawing tools for interactive image segmentation and labeling include active contours or boundaries, scribbles, rectangles and other shapes. Thin vessel shapes in images of vascular networks are difficult to segment using automatic or interactive methods. This paper introduces the novel use of a sparse set of user-defined seed points (supervised labels) for precisely, quickly and robustly segmenting complex biomedical images. A multiquadric spline-based binary classifier is proposed as a unique approach for interactive segmentation using as features color values and the location of seed points...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227683/artsens-%C3%A2-mobile-a-portable-image-free-platform-for-automated-evaluation-of-vascular-stiffness
#4
Malay Ilesh Shah, Jayaraj Joseph, T Aryasree, Mohanasankar Sivaprakasam, Malay Ilesh Shah, Jayaraj Joseph, T Aryasree, Mohanasankar Sivaprakasam, T Aryasree, Mohanasankar Sivaprakasam, Jayaraj Joseph, Malay Ilesh Shah
Vascular stiffness is a key physiological marker significant in screening and early diagnosis of vascular disease. However, state of art techniques for vascular stiffness evaluation are not suited for field deployment. We present ARTSENS(®) Mobile, a portable, image-free ultrasound technology platform for automated evaluation of carotid artery stiffness, amenable for field deployment. The technology utilises a single element ultrasound transducer operated in pulse echo modality to investigate arterial wall dynamics, assisted by intelligent algorithms for wall identification and motion tracking to completely automate the measurement...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227428/calcification-detection-of-abdominal-aorta-in-ct-images-and-3d-visualization-in-vr-devices
#5
Jose A Garcia-Berna, Juan M Sanchez-Gomez, Judith Hermanns, Gines Garcia-Mateos, Jose L Fernandez-Aleman, Jose A Garcia-Berna, Juan M Sanchez-Gomez, Judith Hermanns, Gines Garcia-Mateos, Jose L Fernandez-Aleman, Jose L Fernandez-Aleman, Jose A Garcia-Berna, Judith Hermanns, Juan M Sanchez-Gomez, Gines Garcia-Mateos
Automatic calcification detection in abdominal aorta consists of a set of computer vision techniques to quantify the amount of calcium that is found around this artery. Knowing that information, it is possible to perform statistical studies that relate vascular diseases with the presence of calcium in these structures. To facilitate the detection in CT images, a contrast is usually injected into the circulatory system of the patients to distinguish the aorta from other body tissues and organs. This contrast increases the absorption of X-rays by human blood, making it easier the measurement of calcifications...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227209/high-speed-in-vivo-imaging-of-retinal-hemodynamics-in-a-rodent-model-of-hypertension
#6
Mahdieh Rezaeian, Dana Georgevsky, S Mojtaba Golzan, Stuart L Graham, Mahdieh Rezaeian, Dana Georgevsky, S Mojtaba Golzan, Stuart L Graham, Dana Georgevsky, Mahdieh Rezaeian, S Mojtaba Golzan, Stuart L Graham
The eye is the only organ through which microcirculation can be visualized non-invasively. This unique feature makes the eye and specifically retinal vasculature an excellent target area to monitor and study micro-vascular damage in systemic diseases. Dynamic (real-time) changes of retinal vessels have been shown to be more specific to the disease in comparison with static measurements. In this study we utilize high speed imaging (i.e. 125 fps) to study and derive dynamic changes of retinal vessels in a rat model of hypertension...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227041/deformable-resection-process-map-for-intraoperative-cutting-guides
#7
Megumi Nakao, Kojiro Taura, Tetsuya Matsuda, Megumi Nakao, Kojiro Taura, Tetsuya Matsuda, Megumi Nakao, Kojiro Taura, Tetsuya Matsuda
In this paper, we will introduce the concept of deformable resection process mapping as a time-varying geometric guide for soft tissue tumor resection procedures. The deformable resection process map (RPM) estimates the local appearance of vascular structures after cuts as a novel guide. The RPM can be directly generated from patient-specific medical images using volumetric resampling techniques. Since user input of some cutting points is the only requirement for generating the RPM, the developed software will be directly available for clinical use to preview surgical procedures and intraoperative workflow management without time-consuming setups or additional workloads...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226713/automatic-workflow-for-narrow-band-laryngeal-video-stitching
#8
Sara Moccia, Veronica Penza, Gabriele Omodeo Vanone, Elena De Momi, Leonardo S Mattos, Sara Moccia, Veronica Penza, Gabriele Omodeo Vanone, Elena De Momi, Leonardo S Mattos, Elena De Momi, Leonardo S Mattos, Gabriele Omodeo Vanone, Veronica Penza, Sara Moccia
In narrow band (NB) laryngeal endoscopy, the clinician usually positions the endoscope near the tissue for a correct inspection of possible vascular pattern alterations, indicative of laryngeal malignancies. The video is usually reviewed many times to refine the diagnosis, resulting in loss of time since the salient frames of the video are mixed with blurred, noisy, and redundant frames caused by the endoscope movements. The aim of this work is to provide to the clinician a unique larynx panorama, obtained through an automatic frame selection strategy to discard non-informative frames...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226682/extraction-of-medically-interpretable-features-for-classification-of-malignancy-in-breast-thermography
#9
Himanshu Madhu, Siva Teja Kakileti, Krithika Venkataramani, Susmija Jabbireddy, Himanshu Madhu, Siva Teja Kakileti, Krithika Venkataramani, Susmija Jabbireddy, Susmija Jabbireddy, Krithika Venkataramani, Siva Teja Kakileti, Himanshu Madhu
Thermography, with high-resolution cameras, is being re-investigated as a possible breast cancer screening imaging modality, as it does not have the harmful radiation effects of mammography. This paper focuses on automatic extraction of medically interpretable non-vascular thermal features. We design these features to differentiate malignancy from different non-malignancy conditions, including hormone sensitive tissues and certain benign conditions, which have an increased thermal response. These features increase the specificity for breast cancer screening, which had been a long known problem in thermographic screening, while retaining high sensitivity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225811/automated-numerical-simulation-of-biological-pattern-formation-based-on-visual-feedback-simulation-framework
#10
Mingzhu Sun, Hui Xu, Xingjuan Zeng, Xin Zhao
There are various fantastic biological phenomena in biological pattern formation. Mathematical modeling using reaction-diffusion partial differential equation systems is employed to study the mechanism of pattern formation. However, model parameter selection is both difficult and time consuming. In this paper, a visual feedback simulation framework is proposed to calculate the parameters of a mathematical model automatically based on the basic principle of feedback control. In the simulation framework, the simulation results are visualized, and the image features are extracted as the system feedback...
2017: PloS One
https://www.readbyqxmd.com/read/28225687/reducing-iodine-contrast-volume-in-ct-angiography-of-the-abdominal-aorta-using-integrated-tube-potential-selection-and-weight-based-method-without-compromising-image-quality
#11
Rogerio Vasconcelos, Terri J Vrtiska, Thomas A Foley, Thanila A Macedo, Juan C Montoya Cardona, Eric E Williamson, Cynthia H McCollough, Joel G Fletcher
OBJECTIVE: The purpose of this study is to determine whether image quality was maintained when a weight-based protocol incorporating tube potential selection was used to select lower iodine contrast volumes for aortic CT angiography (CTA). MATERIALS AND METHODS: Patients with potentially decreased renal function underwent CTA performed with the iodinated contrast volume determined using a table incorporating different tube potentials and patient weights. The image quality of CTA examinations performed with a reduced iodine volume (hereafter known as "low-iodine CTA examinations"), internal control CTA examinations (i...
March 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28224925/diabetes-mellitus-is-a-coronary-heart-disease-risk-equivalent-for-peripheral-vascular-disease
#12
Jonathan D Newman, Caron B Rockman, Mikhail Kosiborod, Yu Guo, Hua Zhong, Howard S Weintraub, Arthur Z Schwartzbard, Mark A Adelman, Jeffrey S Berger
: Diabetes mellitus (diabetes) is associated with significantly increased risk of peripheral vascular disease. Diabetes is classified as a coronary heart disease (CHD) risk equivalent, but it is unknown whether diabetes is a CHD risk equivalent for peripheral vascular disease. The objective was to evaluate the odds of peripheral arterial disease (PAD) or carotid artery stenosis (CAS) among participants with diabetes, CHD, or both, compared with participants without diabetes or CHD, in a nationwide vascular screening database...
February 2017: American Heart Journal
https://www.readbyqxmd.com/read/28224399/can-neuroimaging-differentiate-pfo-and-af-related-cardioembolic-stroke-from-the-other-embolic-sources-clinical-radiological-correlation-on-a-retrospective-study
#13
Alessandro Stecco, Martina Quagliozzi, Eleonora Soligo, Andrea Naldi, Alessia Cassarà, Lorenzo Coppo, Roberta Rosso, Angelo Sante Bongo, Paola Amatuzzo, Francesco Buemi, Elena Guenzi, Alessandro Carriero
PURPOSE: The aim of this retrospective study was to map the specific ischemic lesion patterns of distribution in patent foramen ovale-related stroke (PFO-stroke) and atrial fibrillation-related stroke (AF-stroke) in patients with idiopatic ischemic stroke. MATERIALS AND METHODS: 750 ischaemic strokes were screened on basis of diagnostic imaging and tests: patients with known causes were excluded. 171 patients with unknown cause were selected and divided in two groups: AF-stroke (43 patients) and PFO-stroke (128 patients)...
February 21, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28224304/visualization-of-draining-vein-in-focal-nodular-hyperplasia-by-superb-microvascular-imaging-report-of-two-cases
#14
Hiroko Naganuma, Hideaki Ishida, Masahiro Ogawa, Katsunori Suzuki
Focal nodular hyperplasia (FNH) is the second most common benign tumor of the liver, and diagnosis and follow-up without invasive procedures are now highly recommended. FNH shows a characteristic vascular structure called "spoke-wheel appearance". However, this appearance relies on the mode of the feeding artery, and the mode of the draining vein has not been sufficiently studied until recently. Superb microvascular imaging (SMI) is a new Doppler technology designed to improve visualization of the blood flow, especially slow flow signals from fine vessels, using a new algorithm...
February 21, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28224216/vascular-surgery-the-main-risk-factor-for-mortality-in-146-takayasu-arteritis-patients
#15
Nilton Salles Rosa Neto, Samuel Katsuyuki Shinjo, Maurício Levy-Neto, Rosa Maria Rodrigues Pereira
Takayasu arteritis (TA) is an idiopathic chronic inflammatory disease that affects the aorta and its main branches. According to disease involvement, patients may require surgical treatment mainly due ischemic lesions in association with medical therapy. We evaluated the impact of vascular interventions in a cohort of TA patients. Medical records from 146 TA patients were reviewed. Clinical features, medical, and surgical treatment were revised and disease activity was determined by clinical, laboratorial, and imaging parameters...
February 21, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28224101/vein-of-galen-malformation-in-a-neonate-a-case-report-and-review-of-endovascular-management
#16
Surasak Puvabanditsin, Rajeev Mehta, Kristy Palomares, Natalie Gengel, Christina Ferrucci Da Silva, Sudipta Roychowdhury, Gaurav Gupta, Arun Kashyap, David Sorrentino
Vein of Galen malformation (VOGM) is a rare congenital vascular malformation caused by the maldevelopment of its embryonic precursor, the median prosencephalic vein of Markowski. VOGM results in neonatal morbidity and mortality, and premature delivery does not improve the outcome. We report a term female neonate in whom a vein of Galen malformation was diagnosed prenatally at 37 wk of gestation during a growth ultrasound and confirmed by fetal magnetic resonance imaging. Signs of cardiac decompensation were evident in the fetus...
February 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28224089/kilt-kidney-and-ivc-abnormalities-with-leg-thrombosis-syndrome-in-a-41-years-old-man-with-loin-pain-and-fever
#17
James Kiujing Fung, Victor Hip Wo Yeung, Sau Kwan Chu, Chi Wan Man
KILT syndrome is a rare condition composing the triad of kidney and inferior vena cava anomaly and extensive venous thrombosis. We present a case of newly diagnosed KILT syndrome in a 41-years-old gentleman presenting with loin pain and fever. Reviewing previous case reports, KILT syndrome is usually an incidental finding on imaging studies and there is a wide scope of initial clinical presentations. However, recent evidence suggests IVC anomaly may have caused subsequent renal hypoplasia. Identification of the underlying etiology may be helpful in planning early vascular intervention to treat the condition...
May 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28223802/fe3o4-based-plga-nanoparticles-as-mr-contrast-agents-for-the-detection-of-thrombosis
#18
Jia Liu, Jie Xu, Jun Zhou, Yu Zhang, Dajing Guo, Zhigang Wang
Thrombotic disease is a great threat to human health, and early detection is particularly important. Magnetic resonance (MR) molecular imaging provides noninvasive imaging with the potential for early disease diagnosis. In this study, we developed Fe3O4-based poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) surface-modified with a cyclic Arg-Gly-Asp (cRGD) peptide as an MR contrast agent for the detection of thrombosis. The physical and chemical characteristics, biological toxicity, ability to target thrombi, and biodistribution of the NPs were studied...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28223171/how-tumour-induced-vascular-changes-alter-angiogenesis-insights-from-a-computational-model
#19
A Stéphanou, A C Lesart, J Deverchère, A Juhem, A Popov, F Estève
A computational model was developed to describe experimentally observed vascular changes induced by the introduction of a tumour on a mouse equipped with a dorsal skinfold chamber. The vascular structure of the host tissue was segmented from in vivo images and transposed into the computational framework. Simulations of tumour-induced vascular changes were performed and include the destabilizing effects of the growth factor VEGF on the integrity of the vessels walls. The integration of those effects, that include alteration of the vessel wall elasticity and wall breaching, were required to realistically reproduce the experimental observations...
February 18, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28223154/idiopathic-and-systemic-sclerosis-associated-pulmonary-arterial-hypertension-a-comparison-of-demographic-haemodynamic-and-magnetic-resonance-imaging-characteristics-and-outcomes
#20
Sheila Ramjug, Nehal Hussain, Judith Hurdman, Catherine Billings, Athanasios Charampopoulos, Charlie A Elliot, David G Kiely, Ian Sabroe, Smitha Rajaram, Andrew J Swift, Robin Condliffe
BACKGROUND: Previous studies have identified survival in systemic sclerosis (SSc)-associated pulmonary arterial hypertension (SSc-PAH) to be worse than in idiopathic pulmonary arterial hypertension (IPAH). We investigated differences between these conditions by comparing demographic, haemodynamic and radiological characteristics and outcomes in a large cohort of incident patients. METHODS: 651 patients diagnosed with IPAH or SSc-associated pre-capillary pulmonary hypertension were included...
February 18, 2017: Chest
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