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Vascular imaging

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https://www.readbyqxmd.com/read/28527198/contrast-enhanced-ultrasound-ceus-in-an-interdisciplinary-intensive-care-unit-icu-diagnostic-efficacy-in-the-assessment-of-post-operative-complications-compared-to-contrast-enhanced-computed-tomography-cect-first-results
#1
M Georgieva, L Beyer, I Goecze, C Stroszczynski, P Wiggermann, E M Jung
To evaluate the effectiveness of high-resolution contrast-enhanced ultrasound (CEUS) to diagnose early post-operative complications in an interdisciplinary intensive care unit.In 50 patients (male 32; female 18) 64 CEUS examinations were performed in an intensive care unit (ICU) setting to detect post-operative complications. Multi-frequency transducer (1-5 and/or 6-9 MHz) were used. All 64 examinations were performed by one experienced examiner. CEUS findings were compared with contrast-enhanced computed tomography (CECT) findings...
May 19, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28527065/migraine-with-aura-white-matter-lesions-preliminary-data-on-clinical-aspects
#2
Alberto Galli, P Di Fiore, G D'Arrigo, C Uggetti, S Squarza, M Leone, D D'Amico, F Frediani
A few clinic-based magnetic resonance imaging studies report an increased risk of signal abnormalities in migraineurs brain's white matter, especially in migraine with aura subjects. A vascular genesis has been hypnotized and migraine with aura was considered an independent risk factor for stroke. Available data of magnetic resonance imaging alterations are often nonspecific and sometimes controversial. The aim of our study is to investigate migraine with aura patients with standardized brain magnetic resonance imaging to detect and to quantify the presence of white matter lesions and to analyze their relation with clinical data...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28526945/tri-scan-a-three-stage-color-enhancement-tool-for-endoscopic-images
#3
Mohammad S Imtiaz, Shahed K Mohammed, Farah Deeba, Khan A Wahid
Modern endoscopes play a significant role in diagnosing various gastrointestinal (GI) tract related diseases where the visual quality of endoscopic images helps improving the diagnosis. This article presents an image enhancement method for color endoscopic images that consists of three stages, and hence termed as "Tri-scan" enhancement: (1) tissue and surface enhancement: a modified linear unsharp masking is used to sharpen the surface and edges of tissue and vascular characteristics; (2) mucosa layer enhancement: an adaptive sigmoid function is employed on the R plane of the image to highlight micro-vessels of the superficial layers of the mucosa and submucosa; and (3) color tone enhancement: the pixels are uniformly distributed to create an enhanced color effect to highlight the subtle micro-vessels, mucosa and tissue characteristics...
June 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28526859/evaluation-of-arteriolar-smooth-muscle-cell-function-in-an-ex-vivo-microvascular-network-model
#4
Jessica M Motherwell, Mohammad S Azimi, Kristine Spicer, Natascha G Alves, Nicholas A Hodges, Jerome W Breslin, Prasad V G Katakam, Walter L Murfee
An emerging challenge in tissue engineering biomimetic models is recapitulating the physiological complexity associated with real tissues. Recently, our laboratory introduced the rat mesentery culture model as an ex vivo experimental platform for investigating the multi-cellular dynamics involved in angiogenesis within an intact microvascular network using time-lapse imaging. A critical question remains whether the vessels maintain their functionality. The objective of this study was to determine whether vascular smooth muscle cells in cultured microvascular networks maintain the ability to constrict...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28526753/altered-feto-placental-vascularization-feto-placental-malperfusion-and-fetal-growth-restriction-in-mice-with-egfl7-loss-of-function
#5
Lauretta A Lacko, Romulo Hurtado, Samantha Hinds, Michael G Poulos, Jason M Butler, Heidi Stuhlmann
EGFL7 is a secreted, angiogenic factor produced by embryonic endothelial cells. To understand its role in placental development, we established a novel Egfl7 knockout mouse. The mutant mice have gross defects in chorioallantoic branching morphogenesis and placental vascular patterning. Microangiography and 3D imaging revealed patchy perfusion of Egfl7(-/-) placentas marked by impeded blood conductance through sites of narrowed vessels. Consistent with poor feto-placental perfusion, Egfl7 knockout resulted in reduced placental weight and fetal growth restriction...
May 19, 2017: Development
https://www.readbyqxmd.com/read/28525681/unveiling-idiopathic-macular-telangiectasia-clinical-applications-of-optical-coherence-tomography-angiography
#6
Marco A Gonzalez, Diana Shechtman, Jay M Haynie, Leo Semes
PURPOSE: Idiopathic macular telangiectasia type 2 (IMT2) is a bilateral acquired maculopathy, with a spectrum of clinical presentations associated with inner retinal telangiectatic vascular anomalies. Cases often are underdiagnosed or misdiagnosed. Current diagnostic modalities such as spectral-domain optical coherence tomography (SD-OCT) and fluorescein angiography (FA) are valuable to the understanding of the clinicopathology. More recently, optical coherence tomography angiography (OCTA), as an emerging noninvasive technology, has been shown to be particularly useful in the assessment and management of IMT2...
May 19, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28525557/retinal-vascular-branching-in-healthy-and-diabetic-subjects
#7
Ting Luo, Thomas J Gast, Tyler J Vermeer, Stephen A Burns
Purpose: To measure the effect of nonproliferative diabetic retinopathy (NPDR) on retinal branching. To compare vascular branching in healthy and diabetic subjects with established biophysical models. Methods: Vascular bifurcations in arteries and veins were imaged in 17 NPDR and 26 healthy subjects with the Indiana adaptive optics scanning laser ophthalmoscope (AOSLO). Vessel measurements were grouped according to parent vessel diameters into large (≤50 ∼ <100 μm) and small (≤20 ∼ <50 μm) sizes...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28524373/sialic-acids-regulate-microvessel-permeability-revealed-by-novel-in-vivo-studies-of-endothelial-glycocalyx-structure-and-function
#8
Kai Betteridge, Kenton Arkill, Chris Neal, Steve Harper, Becky Foster, Simon Satchell, David Bates, Andy Salmon
The endothelial glycocalyx forms a continuous coat over the luminal surface of all vessels, and regulates multiple vascular functions. The contribution of individual components of the endothelial glycocalyx to one critical vascular function, microvascular permeability, remains unclear. We developed novel, real-time, paired methodologies to study the contribution of sialic acids within the endothelial glycocalyx to the structural and functional permeability properties of the same microvessel in vivo. Single perfused rat mesenteric microvessels were perfused with fluorescent endothelial cell membrane and glycocalyx labels, and imaged with confocal microscopy...
May 19, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28523824/laser-desorption-ionisation-mass-spectrometry-imaging-of-european-yew-taxus-baccata-on-gold-nanoparticle-enhanced-target
#9
Adrian Arendowski, Tomasz Ruman
INTRODUCTION: European yew (Taxus baccata) is a plant known to man for centuries as it produces many interesting and important metabolites. These chemical compounds were repeatedly analysed by various analytical techniques, but none of the methods used so far allowed the localisation of the chemical compounds within the tissue and also correlation between plant morphology and its biochemistry. OBJECTIVE: Visualisation of the spatial distribution of yew metabolites with nanoparticle-based mass spectrometry imaging...
May 19, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28523456/bone-marrow-mesenchymal-stem-cell-administration-significantly-improves-outcome-after-retinal-ischemia-in-rats
#10
Biji Mathew, Jacqueline N Poston, John C Dreixler, Leianne Torres, Jasmine Lopez, Ruth Zelkha, Irina Balyasnikova, Maciej S Lesniak, Steven Roth
PURPOSE: Ischemia-associated retinal degeneration is one of the leading causes of vision loss, and to date, there are no effective treatment options. We hypothesized that delayed injection of bone-marrow stem cells (BMSCs) 24 h after the onset of ischemia could effectively rescue ischemic retina from its consequences, including apoptosis, inflammation, and increased vascular permeability, thereby preventing retinal cell loss. METHODS: Retinal ischemia was induced in adult Wistar rats by increasing intraocular pressure (IOP) to 130-135 mmHg for 55 min...
May 18, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28523439/magnetic-resonance-imaging-of-painful-swollen-legs-in-the-emergency-department-a-pictorial-essay
#11
REVIEW
Ashish Chawla, Niraj Dubey, Kian Ming Chew, Dinesh Singh, Vishal Gaikwad, Wilfred Cg Peh
Patients presenting with a painful swollen leg are not infrequently encountered at the emergency department and can pose a diagnostic dilemma for attending physicians. The potential causes of leg pain and swelling include trauma, infection, inflammation, and neurogenic, vascular, and iatrogenic conditions; with magnetic resonance imaging (MRI) being an important tool in evaluation. We describe the MRI features of various conditions causing painful swollen legs. We also discuss the differential diagnosis and the useful clinical and laboratory findings that radiologists should be aware of, in order to arrive at an accurate diagnosis...
May 18, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28523415/pictorial-review-of-vascular-involvement-and-complex-vascular-reconstructions-in-borderline-to-minimally-advanced-pancreatic-malignancies
#12
REVIEW
Donald L Ly, Seng Thipphavong, Boraiah Sreeharsha
PURPOSE: To review borderline resectability criteria for pancreatic malignancies, show examples of few surgically treated minimally advanced pancreatic malignancies, discuss various complex vascular reconstructions, and highlight the imaging appearances. BACKGROUND: Often aggressive surgical approaches are used to treat borderline to minimally advanced pancreatic malignancies in specialist centers. As abdominal radiologists it is essential to have up-to-date knowledge to distinguish such tumors with accuracy and also be well versed with the various vascular reconstructions used in such surgeries...
May 18, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28523170/a-comparison-of-longitudinal-and-transverse-approaches-to-ultrasound-guided-axillary-vein-cannulation-by-experienced-operators
#13
Yi-Zhou He, Ming Zhong, Wei Wu, Jie-Qiong Song, Du-Ming Zhu
BACKGROUND: The axillary vein is an easily accessible vessel that can be used for ultrasound-guided central vascular access and offers an alternative to the internal jugular and subclavian veins. The objective of this study was to identify which transducer orientation, longitudinal or transverse, is better for imaging the axillary vein with ultrasound. METHODS: We analyzed 236 patients who had undergone central venous cannulation of axillary vein in this retrospective study...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28522908/detection-and-characterization-of-murine-colitis-and-carcinogenesis-by-molecularly-targeted-contrast-enhanced-ultrasound
#14
Markus Brückner, Jan Heidemann, Tobias M Nowacki, Friederike Cordes, Jörg Stypmann, Philipp Lenz, Faekah Gohar, Andreas Lügering, Dominik Bettenworth
AIM: To study mucosal addressin cellular adhesion molecule-1 (MAdCAM-1) and vascular endothelial growth factor (VEGF)-targeted contrast enhanced ultrasound (CEUS) for the assessment of murine colitis and carcinogenesis. METHODS: C57BL/6 mice were challenged with 3% dextran sodium-sulfate (DSS) for three, six or nine days to study the development of acute colitis. Ultrasound was performed with and without the addition of unspecific contrast agents. MAdCAM-1-targeted contrast agent was used to detect and quantify MAdCAM-1 expression...
April 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28522676/midlife-and-late-life-vascular-risk-factors-and-white-matter-microstructural-integrity-the-atherosclerosis-risk-in-communities-neurocognitive-study
#15
Melinda C Power, Jonathan V Tingle, Robert I Reid, Juebin Huang, A Richey Sharrett, Josef Coresh, Michael Griswold, Kejal Kantarci, Clifford R Jack, David Knopman, Rebecca F Gottesman, Thomas H Mosley
BACKGROUND: Diffusion tensor imaging measures of white matter (WM) microstructural integrity appear to provide earlier indication of WM injury than WM hyperintensities; however, risk factors for poor WM microstructural integrity have not been established. Our study quantifies the association between vascular risk factors in midlife and late life with measures of late-life WM microstructural integrity. METHODS AND RESULTS: We used data from 1851 participants in ARIC (Atherosclerosis Risk in Communities Study) who completed 3-T magnetic resonance imaging, including diffusion tensor imaging, as part of the ARIC Neurocognitive Study (ARIC-NCS)...
May 18, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28522658/effect-of-fontan-geometry-on-exercise-haemodynamics-and-its-potential-implications
#16
Elaine Tang, Zhenglun Alan Wei, Kevin K Whitehead, Reza H Khiabani, Maria Restrepo, Lucia Mirabella, James Bethel, Stephen M Paridon, Bradley S Marino, Mark A Fogel, Ajit P Yoganathan
OBJECTIVE: Exercise intolerance afflicts Fontan patients with total cavopulmonary connections (TCPCs) causing a reduction in quality of life. Optimising TCPC design is hypothesised to have a beneficial effect on exercise capacity. This study investigates relationships between TCPC geometries and exercise haemodynamics and performance. METHODS: This study included 47 patients who completed metabolic exercise stress test with cardiac magnetic resonance (CMR). Phase-contrast CMR images were acquired immediately following supine lower limb exercise...
May 18, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28522470/three-dimensional-ca-2-imaging-advances-understanding-of-astrocyte-biology
#17
Erika Bindocci, Iaroslav Savtchouk, Nicolas Liaudet, Denise Becker, Giovanni Carriero, Andrea Volterra
Astrocyte communication is typically studied by two-dimensional calcium ion (Ca(2+)) imaging, but this method has not yielded conclusive data on the role of astrocytes in synaptic and vascular function. We developed a three-dimensional two-photon imaging approach and studied Ca(2+) dynamics in entire astrocyte volumes, including during axon-astrocyte interactions. In both awake mice and brain slices, we found that Ca(2+) activity in an individual astrocyte is scattered throughout the cell, largely compartmented between regions, preponderantly local within regions, and heterogeneously distributed regionally and locally...
May 19, 2017: Science
https://www.readbyqxmd.com/read/28522312/intravascular-imaging-in-cardiovascular-ageing
#18
REVIEW
Christos V Bourantas, Tom Crake, Yao-Jun Zhang, Mick Ozkor, Javed Ahmed, Hector M Garcia-Garcia, Patrick W Serruys
Ageing is related to complex molecular, inflammatory and biochemical changes that affect coronary pathology and often lead to coronary artery disease and cardiovascular events. Intravascular imaging is considered as the ideal technique to study coronary plaque morphology and assess its burden. Over the recent years several studies have been performed that investigated the association between pathophysiological mechanisms that promote vascular ageing and plaque morphology. In addition, several reports have compared plaque pathology in different age groups and a few studies included serial intravascular imaging to assess changes in the atheroma burden and compositional characteristics of the plaque...
May 15, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28522155/fibroelastic-pseudotumour-elastofibroma-dorsi-detected-by-18-f-fdg-pet-ct-and-by-posttherapy-radioiodine-spect-ct
#19
M Oporto, F Cepa, N Orta, S Rubí, H Navalón, C Peña
Radioiodine uptake in the thyroid tissue, metastasis of differentiated thyroid cancer (DTC), and in other tissues, depends on the expression of sodium-iodide symporter (NIS). Vascular permeability, effusions, inflammation, and other mechanisms may also play a role in the accumulation of radioactive iodine. A 63-year-old woman underwent radioiodine therapy, as well as a post-therapy whole-body scan,as she was suspected of having lung metastasis from thyroid carcinoma. The scan not only showed uptake at the lung metastasis but also a faint diffuse bilateral uptake in the posterior thorax...
May 15, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28522072/cardiovascular-magnetic-resonance-in-systemic-sclerosis-pearls-and-pitfalls
#20
REVIEW
Sophie I Mavrogeni, Juerg Schwitter, Luna Gargani, Alessia Pepe, Lorenzo Monti, Yannick Allanore, Marco Matucci-Cerinic
Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular dysfunction and excessive fibrosis, involving internal organs including the heart. The estimated prevalence of cardiac involvement in SSc is high and remains subclinical until the late stages. It is either primary, related to myocardial inflammation and fibrosis, or secondary, due to pulmonary arterial hypertension (SSc-PAH) or systemic hypertension, in those patients with renal involvement. Cardiovascular magnetic resonance (CMR) is a useful tool for the early assessment of cardiac involvement in SSc...
March 31, 2017: Seminars in Arthritis and Rheumatism
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