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Éverton L Vogt, Jorge F A Model, Anapaula S Vinagre
Organotins (OTs) are considered some of the most toxic chemicals introduced into aquatic environments by anthropogenic activities. They are widely used for agricultural and industrial purposes and as antifouling additives on boat hull's paints. Even though the use of OTs was banned in 2008, elevated levels of OTs can still be detected in aquatic environments. OTs' deleterious effects upon wildlife and experimental animals are well documented and include endocrine disruption, immunotoxicity, neurotoxicity, genotoxicity, and metabolic dysfunction...
2018: Frontiers in Endocrinology
Aline Souza Pagnussat, Ana F R Kleiner, Carlos R M Rieder, Anapaula Frantz, Jaira Ehlers, Camila Pinto, Gilson Dorneles, Carlos Alexandre Netto, Alessandra Peres, Manuela Galli
BACKGROUND: The decrease of Brain-Derived Neurotrophic Factor (BDNF) serum levels has been related to the pathophysiology of several neurodegenerative diseases as well as to neural plasticity and rehabilitation. Automated Mechanical Peripheral Stimulation (AMPS) has been investigated as a complementary therapy for Parkinson Disease (PD). OBJECTIVES: (1) to investigate the effects of AMPS on BDNF and Cortisol serum levels of subjects with PD; (2) to evidence the interplay between BDNF and Cortisol serum levels and the functional mobility improvement after AMPS treatment...
2018: Restorative Neurology and Neuroscience
Anna S Boser, Bastien Bidaud, Silvia Maues, Noé Guiraud, Anapaula M Mendes, François Lacapere, Sophie Rhodes, Florence Huber, Leila Adriouch, Mathieu Nacher, Emilie Mosnier
No abstract text is available yet for this article.
March 13, 2018: AIDS
Almir G V Bitencourt, Roberta R M Gama, Luciana Graziano, Erika M S Negrão, Silvia M P S Sabino, Anapaula H U Watanabe, Camila S Guatelli, Juliana A Souza, Edmundo C Mauad, Elvira F Marques
Breast metastases from extramammary cancers are rare and usually related to poor prognosis. The extramammary tumours most frequently exhibiting breast metastases are melanoma, lymphomas, ovarian cancer, lung and neuroendocrine tumours, and sarcomas. Owing to the lack of reliable and specific clinical or radiological signs for the diagnosis of breast metastases, a combination of techniques is needed to differentiate these lesions from primary breast carcinoma or even benign breast lesions. Multiple imaging methods may be used to evaluate these patients, including mammography, ultrasound, MRI, CT and positron emission tomography CT...
August 2017: British Journal of Radiology
Anapaula Martins Mendes, João Luiz Bastos, Deise Bresan, Maurício Soares Leite
Objective: This article analyzes the epidemiological situation of tuberculosis in the state of Rio Grande do Sul, emphasizing the indigenous population. The data are based on the Information System of Grievance Notification (Sinan) between 2003 and 2012. Methods: The notified cases of tuberculosis were analyzed according to age, sex, zone of residence, input type, means of diagnosis, clinical form, anti-HIV exam, medical care, supervised treatment (in Portuguese, TDO), closure, and race...
July 2016: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
Emily M Flowers, Tsvetan R Bachvaroff, Janet V Warg, John D Neill, Mary L Killian, Anapaula S Vinagre, Shanai Brown, Andréa Santos E Almeida, Eric J Schott
The blue crab, Callinectes sapidus Rathbun, 1896, which is a commercially important trophic link in coastal ecosystems of the western Atlantic, is infected in both North and South America by C. sapidus Reovirus 1 (CsRV1), a double stranded RNA virus. The 12 genome segments of a North American strain of CsRV1 were sequenced using Ion Torrent technology. Putative functions could be assigned for 3 of the 13 proteins encoded in the genome, based on their similarity to proteins encoded in other reovirus genomes...
2016: Frontiers in Microbiology
Elen Thegla Sander Inohara, Charles Budazewsky Pinto, Jorge Felipe Argenta Model, Márcia Trapp, Luiz Carlos Kucharski, Roselis Silveira Martins Da Silva, Anapaula Sommer Vinagre
In crustaceans, serotonin (5-HT) controls various physiological processes, such as hormonal secretion, color changes, reproduction, and metabolism. Since 5-HT injections cause hyperglycemia, this study was designed to further investigate this action of 5-HT in the crab Neohelice granulate, fed with a high-carbohydrate (HC) or a high-protein (HP) diet. The effects of pre-treatment with mammalian 5-HT receptor antagonists, cyproheptadine and methiothepin, were also investigated. A series of in vivo experiments with (3)H-5-HT was carried out in order to investigate the presence of putative receptors in peripheral tissues...
July 2015: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
René Aloisio da Costa Vieira, Silvia Maria Prioli de Souza Sabino, Gustavo Zucca Matthes, Anapaula Hidemi Uema Watanabe, Lucas Faria Abrahao-Machado
No abstract text is available yet for this article.
November 2014: Revista da Associação Médica Brasileira
Silvia Maria Prioli DE Souza Sabino, Thiago Buosi Silva, Anapaula Hidemi Uema Watanabe, Kari Syrjänen, André Lopes Carvalho, Edmundo Carvalho Mauad
AIM: To evaluate the effect of a clinical quality control program on the final quality of a mammography screening service. MATERIALS AND METHODS: We conducted retrospective assessment of the clinical quality of 5,000 mammograms taken in a Mammography Screening Program between November 2010 and September 2011, following the implementation of a Clinical Quality Control Program based on the European Guidelines. RESULTS: Among the 105,000 evaluated quality items, there were 8,588 failures (8...
September 2014: Anticancer Research
Luciana Nunes Mosca, Tamara Beres Lederer Goldberg, Valéria Nóbrega da Silva, Carla Cristiane da Silva, Cilmery Suemi Kurokawa, Anapaula C Bisi Rizzo, José Eduardo Corrente
OBJECTIVE: The aim of this study was to investigate the effects of excess body fat on bone mass in overweight, obese, and extremely obese adolescents. METHODS: This study included 377 adolescents of both sexes, ages 10 to 19 y. Weight, height, body mass index (BMI), bone age, bone mineral content (BMC), and bone mineral density (BMD) were obtained by dual-energy x-ray absorptiometry. The results were adjusted for chronological age and bone age. Comparisons according to nutritional classification were performed by analysis of variance, followed by Tukey test...
July 2014: Nutrition
Valéria Nóbrega da Silva, Tamara Beres Lederer Goldberg, Luciana Nunes Mosca, Anapaula da Conceição Bisi Rizzo, Altamir dos Santos Teixeira, José Eduardo Corrente
Growing concern has focused on the occurrence of metabolic syndrome (MetS) and its effects on bone mass. There is little information available in the literature concerning the relationship between MetS and BMD in adolescents. The aim of this study was to evaluate the effects of MetS and its components on bone mineral density (BMD) in overweight adolescent boys and girls. This cross-sectional study assessed 271 overweight adolescents with or without MetS (age 10 to 16years). Anthropometric and biochemical tests were performed...
September 2014: Bone
René Aloísio da Costa Vieira, Jorge Shigueo Kunizaki, Abaeté Leite do Canto, Adriano Diniz Baptista Mendes, José Spartaco Vial, Angelo Gustavo Zucca Matthes, Anapaula Uema Watanabe, Cristovam Scapulatempo Neto
INTRODUCTION: Castleman's disease (CD) is a rare disease with unknown etiology and is clinically associated with lymph nodes enlargement. Primary axillary localization of CD represents 2% of the cases. CD rarely occurs in the breasts. PRESENTATION OF CASE: We herein describe a rare case of CD that initially presented in the breast intramammary lymph node and demonstrated axillary adenopathy. Pathologic analysis showed the hyaline vascular form. The patient underwent axillary lymphadenectomy...
2013: International Journal of Surgery Case Reports
Anapaula Cb Rizzo, Tamara Bl Goldberg, Carla C Silva, Cilmery S Kurokawa, Helio Rc Nunes, José E Corrente
BACKGROUND: Obesity in infancy and adolescence has acquired epidemic dimensions worldwide and is considered a risk factor for a number of disorders that can manifest at an early age, such as Metabolic Syndrome (MS). In this study, we evaluated overweight, obese, and extremely obese adolescents for the presence of MS, and studied the prevalence of single factors of the syndrome in this population. METHODS: A total of 321 adolescents (174 females and 147 males) aged 10 to 16 years, attending the Adolescent Outpatient Clinic of Botucatu School of Medicine, Brazil, between April 2009 and April 2011 were enrolled in this study...
2013: Nutrition Journal
Samir Khal Souza, Tiago Leal Martins, Gustavo Dias Ferreira, Anapaula Sommer Vinagre, Roselis Silveira Martins da Silva, Marcos Emilio Frizzo
We reported previously that intrauterine asphyxia acutely affects the rat hippocampus. For this reason, the early effects of this injury were studied in the cerebral cortex, immediately after hysterectomy (acute condition) or following a recovery period at normoxia (recovery condition). Lactacidemia and glycemia were determined, as well as glycogen levels in the muscle, liver and cortex. Cortical tissue was also used to assay the ATP levels and glutamate uptake. Asphyxiated pups exhibited bluish coloring, loss of movement, sporadic gasping and hypertonia...
March 2013: Metabolic Brain Disease
Lisianne Benitez, AnaPaula Correa, Daniel Daroit, Adriano Brandelli
Increased antimicrobial activity was observed when Bacillus amyloliquefaciens LBM 5006 strain was cultivated in the presence of thermally inactivated cells of Escherichia coli, but not with Staphylococcus aureus, Listeria monocytogenes, or Bacillus cereus. E. coli also enhanced the antimicrobial activity when it was added to the medium in the form of living cells or as cell debris after cellular fractionation. No inducing activity was observed with addition of cell-free supernatant of E. coli cultures, suggesting that inducing factor is associated to the cells...
March 2011: Current Microbiology
Silvana S Frassetto, Isis O Alves, Marislane M Santos, Ana E S Schmidt, Janaína J Lopes, Paulo A Oliveira, Anapaula S Vinagre, Patrícia Pereira
UNLABELLED: INTRODUSTION: Sibutramine has been described as a drug recommended for treatment of obesity, since it has the ability to inhibit the reuptake of serotonin and noradrenaline in the central nervous system, thereby increasing energy expenditure. OBJECTIVE: Investigate the anxiogenic and anxiolytic effects of acute and chronic treatment with sibutramine in rats submitted to the task of the elevated plus-maze. METHODS: Diazepam was used as a positive control for the anxiolytic effect, and the task of the elevated plus-maze showed sensitivity to detect the effect...
June 2010: Arquivos Brasileiros de Endocrinologia e Metabologia
Graziani de Freitas Antunes, Ana Paula Nunes do Amaral, Fabiana Pinto Ribarcki, Elenir de Fátima Wiilland, Denise Maria Zancan, Anapaula Sommer Vinagre
The ghost crab, Ocypode quadrata, is found on sandy beaches from the United States to Southern Brazil. Because there is still little information about the metabolism and reproduction of O. quadrata on the southern coast of Brazil, the objectives of this study were to (i) evaluate the effect of seasonal variations on the carbohydrate, lipid, and protein metabolism of O. quadrata at Rondinha Beach, a beach with high anthropogenic activity, and to compare it with data from Siriú Beach, which has less human activity; and (ii) describe the effect of seasonal variations on the histological characteristics of male and female gonads, in order to assess the reproductive capacity of the crabs...
June 1, 2010: Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
Silvana Soriano Frassetto, Angela Della Santa Rubio, Janaína Jardim Lopes, Patrícia Pereira, Clarice Brum, Márcia Khazzaka, Anapaula Sommer Vinagre
Sibutramine has been described as an anti-obesity drug with the ability to inhibit serotonin (5-HT), noradrenaline, and dopamine re-uptake, but without affinity to histamine and muscarinic receptors. On the other hand, cyproheptadine antagonizes serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C), histamine H1, and muscarinic (M) receptors. There are many reports concerning the influence of sibutramine on central serotoninergic pathways. In this study, we suggest that peripheral pathways may also be involved in the serotoninergic effects of sibutramine...
December 2006: Canadian Journal of Physiology and Pharmacology
Anapaula Sommer Vinagre, Ana Paula Nunes do Amaral, Fabiana Pinto Ribarcki, Eliane Fraga da Silveira, Eduardo Périco
The aim of this study was to analyze the seasonal variations of carbohydrate and lipid metabolism of the ghost crab Ocypode quadrata (Fabricius, 1787) on a sandy beach in the southern region of Brazil. Crabs and hemolymph samples were collected monthly in the field. Hepatopancreas, gills, gonads and claw muscles were used for glycogen determination. In males, blood glucose levels increased in the summer and in the winter. The glycogen values increased significantly in the hepatopancreas in the winter, but remained constant in the muscle, gonads and gills...
April 2007: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
Maria Cristina Borsatto, Silmara Aparecida Milori Corona, Anapaula Gomes Alves, Daniela Thomazatti Chimello, Alma Blásida Elizaur Catirse, Regina Guenka Palma-Dibb
PURPOSE: To assess quantitatively the influence of salivary contamination in vitro on marginal microleakage of pit and fissure sealants. METHODS: Forty-eight sound human third molars were selected and assigned to three groups: 1) Fluroshield (F), 2) Single Bond + Fluroshield (SBF) and 3) Ketac-fil (KF). Each group was divided into two subgroups: control (C) and with salivary contamination (SC). The occlusal surfaces were etched with 40% polyacrylic acid for 10 seconds or 37% phosphoric acid for 30 seconds, for either glass-ionomer or resin-based sealants, respectively...
October 2004: American Journal of Dentistry
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