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https://www.readbyqxmd.com/read/28922746/ectopic-expression-of-winding-1-leads-to-asymmetrical-distribution-of-auxin-and-a-spiral-phenotype-in-rice
#1
Ming-Lung Cheng, Shuen-Fang Lo, An-Shan Hsiao, Ya-Fang Hong, Su-May Yu, Tuan-Hua David Ho
Ectopic expression of the rice WINDING 1 (WIN1) gene leads to a spiral phenotype only in shoots but not in roots. Rice WIN1 belongs to a specific class of proteins in cereal plants containing a Bric-a-Brac/Tramtrack/Broad (BTB) complex, a non-phototropic hypocotyl 3 (NPH3) domain and a coiled-coil motif. The WIN1 protein is predominantly localized to the plasma membrane, but is also co-localized to plasmodesmata, where it exhibits a punctate pattern. It is observed that WIN1 is normally expressed in roots and the shoot-root junction, but not in the rest of shoots...
September 1, 2017: Plant & Cell Physiology
https://www.readbyqxmd.com/read/28922738/mixed-symptoms-in-major-depressive-and-bipolar-disorders-a-systematic-review
#2
REVIEW
Gustavo H Vázquez, María Lolich, Casimiro Cabrera, Ruzica Jokic, Dusan Kolar, Leonardo Tondo, Ross J Baldessarini
BACKGROUND: The DSM-5 mixed features specifier for mood disorders encourages renewed interest in mixed states and led us to pool research findings regarding prevalence of mixed features in episodes of major depressive (MDD) and bipolar disorders (BD). METHODS: We systematically searched to July 2017 for reports on mixed symptoms in depressive episodes of MDD and in depression and mania or hypomania in types I and II BD. For primary mood-states and diagnostic groups we compared rates of the presence of mixed symptoms: as defined by DSM-5 (≥3 features opposite to the dominant mood-polarity but not overlapping those of the primary disorder) or as having any ≥3 features of opposite polarity...
September 8, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28922687/comparison-of-perioperative-renal-and-oncologic-outcomes-in-robotic-assisted-versus-open-partial-nephrectomy
#3
Jo-Lynn Tan, Mark Frydenberg, Jeremy Grummet, Uri Hanegbi, Ross Snow, Sarah Mann, Kirobel Begashaw, Daniel Moon
BACKGROUND: To compare perioperative, renal and oncological outcomes after robotic-assisted partial nephrectomy (RAPN) versus open partial nephrectomy (OPN) for the treatment of renal tumours. METHODS: All partial nephrectomies performed at a Metropolitan Urology Centre between 2010 and 2016 were analysed. Baseline data was collected for patient demographics, tumour characteristics (tumour size, laterality and polarity, RENAL scores), and perioperative variables (e...
September 18, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28922605/alkane-coiling-in-perfluoroalkane-solutions-a-new-primitive-solvophobic-effect
#4
Pedro Morgado, Ana Rosa Garcia, Luís F G Martins, Laura M Ilharco, Eduardo J M Filipe
In this work we demonstrate that n-alkanes coil when mixed with perfluoroalkanes, changing their conformational equilibria to more globular states, with a higher number of gauche conformations. The new coiling effect is here observed in fluids governed exclusively by dispersion interactions, contrarily to other examples in which hydrogen bonding and polarity play important roles. FTIR spectra of liquid mixtures of n-hexane and perfluorohexane unambiguously reveal that the population of n-hexane molecules in all-trans conformation reduces from 32% in the pure n-alkane to practically zero...
September 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28922521/molecular-and-morphological-characterization-of-anncaliia-azovica-sp-n-microsporidia-infecting-niphargogammarus-intermedius-crustacea-amphipoda-from-the-azov-sea
#5
Yuri S Tokarev, Yuliya Y Sokolova, Aleksandra A Vasilieva, Irma V Issi
Five out of one hundred adults of Niphargogammarus intermedius caught at the Azov sea shore were found to be infected with microsporidia. The infection was found in the subcuticular fat body and myocytes. Parasites developed in direct contact with host cells, displayed a disporoblastic sporogony and diplokaryotic arrangement of nuclei at all stages. Spores were oval, 4.6-5.8x2.6-3.0 μm. Exospore appendages, vesicular-tubular secretions and the anisofilar polar filament indicated a similarity to Anncaliia species...
September 18, 2017: Journal of Eukaryotic Microbiology
https://www.readbyqxmd.com/read/28922400/protein-folding-misfolding-and-aggregation-the-importance-of-two-electron-stabilizing-interactions
#6
Andrzej Stanisław Cieplak
Proteins associated with neurodegenerative diseases are highly pleiomorphic and may adopt an all-α-helical fold in one environment, assemble into all-β-sheet or collapse into a coil in another, and rapidly polymerize in yet another one via divergent aggregation pathways that yield broad diversity of aggregates' morphology. A thorough understanding of this behaviour may be necessary to develop a treatment for Alzheimer's and related disorders. Unfortunately, our present comprehension of folding and misfolding is limited for want of a physicochemical theory of protein secondary and tertiary structure...
2017: PloS One
https://www.readbyqxmd.com/read/28922111/optimization-of-the-working-conditions-for-magnetic-nanoparticle-enhanced-microwave-diagnostics-of-breast-cancer
#7
Gennaro Bellizzi, Gennaro G Bellizzi, Ovidio M Bucci, Lorenzo Crocco, Marko Helbig, Sebastian Ley, Juergen Sachs
Magnetic nanoparticle-aided microwave imaging is recently gaining an increasing interest as potential tool for breast cancer diagnostics. This is due to the peculiar features of magnetic nanoparticles, which are biocompatible, can be selectively targeted to the tumor and may change their microwave magnetic response when modulated by a polarizing magnetic field. This latter aspect is particularly appealing, as it enables the physical separation of the microwave signal due the malignancy, targeted by the nanoparticles, from that due to healthy tissue...
September 18, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28921994/anisotropic-cracking-of-nanocrystal-superlattices
#8
Benjamin T Diroll, Xuedan Ma, Yaoting Wu, Christopher B Murray
The synthesis colloidal nanocrystals in non-polar organic solvents has led to exceptional size- and shape-control, enabling the formation of nanocrystal superlattices isostructural to atomic lattices built with nanocrystals rather than atoms. The long aliphatic ligands (e.g. oleic acid) used to achieve this control separate nanocrystals too far in the solid-state for most charge-transporting devices. Solid-state ligand exchange, which brings particles closer together and enhances conductivity, necessitates large changes in the total volume of the solid (compressive stress), which leads to film cracking...
September 18, 2017: Nano Letters
https://www.readbyqxmd.com/read/28921963/direct-vapor-growth-of-perovskite-cspbbr3-nanoplate-electroluminescence-devices
#9
Xuelu Hu, Hong Zhou, Zhenyu Jiang, Xiao Wang, Shuangping Yuan, Jianyue Lan, Yongping Fu, Xuehong Zhang, Weihao Zheng, Xiaoxia Wang, Xiaoli Zhu, Lei Liao, Gengzhao Xu, Song Jin, Anlian Pan
Metal halide perovskite nanostructures hold great promises as nanoscale light sources for integrated photonics due to their excellent optoelectronic properties. However, it remains a great challenge to fabricate halide perovskite nanodevices using traditional lithographic methods, because the halide perovskites can be dissolved in the polar solvents that are required in the traditional device fabrication process. Herein, we report single CsPbBr3 nanoplate electroluminescence (EL) devices fabricated by directly growing CsPbBr3 nanoplates on pre-patterned indium tin oxide (ITO) electrodes via a vapor-phase deposition...
September 18, 2017: ACS Nano
https://www.readbyqxmd.com/read/28921928/inverted-formins-a-sub-family-of-atypical-formins
#10
REVIEW
Anna Hegsted, Curtis V Yingling, David Pruyne
Formins are a family of regulators of actin and microtubule dynamics that are present in almost all eukaryotes. These proteins are involved in many cellular processes, including cytokinesis, stress fiber formation, and cell polarization. Here we review one sub-family of formins, the inverted formins. Inverted formins as a group break several formin stereotypes, having atypical biochemical properties and domain organization, and they have been linked to kidney disease and neuropathy in humans. In this review, we will explore recent research on members of the inverted formin sub-family in mammals, zebrafish, fruit flies, and worms...
September 16, 2017: Cytoskeleton
https://www.readbyqxmd.com/read/28921874/polaronic-charge-carrier-lattice-interaction-in-lead-halide-perovskites
#11
Christoph Wolf, Young-Hoon Kim, Himchan Cho, Tae-Woo Lee
Almost ten years after the renaissance of the popular perovskite-type semiconductors based on lead-salts with general formula AMX3 (A=organic or inorganic cation, M=divalent metal, X=halide), many facets of photophysics continue to puzzle researchers. In this review, we shed some light on the low mobilities of charge carriers in lead-halide perovskites with special focus on the lattice properties at non-zero temperature. The polar and soft lattice leads to pronounced electron-phonon coupling, limiting carrier mobility and retarding recombination...
September 18, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28921848/interconversion-rates-between-conformational-states-as-rationale-for-the-membrane-permeability-of-cyclosporines
#12
Jagna Witek, Max Mühlbauer, Bettina G Keller, Markus Blatter, Axel Meissner, Trixie Wagner, Sereina Riniker
Cyclic peptides have regained interest as potential inhibitors of challenging targets, but have often a low bioavailability. The natural product cyclosporine A (CsA) is the textbook exception. Despite its size and polar backbone it is able to passively cross membranes. This ability is hypothesized to be due to a conformational change from the low-energy conformation in water to a "congruent" conformation that is populated both in water and inside the membrane. Here, we use a combination of NMR measurements and kinetic models based on molecular dynamics simulations to rationalize the difference in the membrane permeability of cyclosporine E (CsE) and CsA...
September 17, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28921771/iron-deficiency-stress-can-induce-mxnas1-protein-expression-to-facilitate-iron-redistribution-in-malus-xiaojinensis
#13
Chaohua Sun, Mudan Yuan, Longmei Zhai, Duyue Li, Xinzhong Zhang, Ting Wu, Xuefeng Xu, Yi Wang, Zhenhai Han
Iron (Fe) is a vital trace element in plants and deficiency of this element in apple trees can reduce fruit quality. Nicotianamine (NA) is known to play an important role in Fe transport and endogenous hormone balance. In the present study, we investigated the role of a nicotianamine synthase 1 gene (MxNas1) in an apple species, Malus xiaojinensis, that has an Fe-efficient genotype than other apple species and ecotypes. To characterize the response of M. xiaojinensis to Fe-deficiency, we used quantitative Q-PCR to determine the level of expression of MxNas1 and western blot to measure protein levels...
September 16, 2017: Plant Biology
https://www.readbyqxmd.com/read/28921621/-but-we-want-to-work-the-movement-of-child-workers-in-peru-and-the-actions-for-reducing-child-labor
#14
Isidro Maya Jariego
The program Edúcame Primero (Educate Me First) is an evidence-based practice for eradicating child labor that has been applied with positive results in Colombia, Peru, and several Central American countries. In this article, we describe the difficulties of implementing the program in two poor areas of Lima (Peru) between 2014 and 2016. Specifically, we discuss three ethical challenges faced during the implementation of the program: (a) the existence of a movement of working children that defends the right of children to work; (b) the polarization of some community-based associations and government institutions on how to deal with the problems of working children; and (c) the use of network indicators in the evaluation of the community's level of cohesion...
September 18, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28921568/neuronal-activity-dependent-local-activation-of-dendritic-unfolded-protein-response-promotes-expression-of-brain-derived-neurotrophic-factor-in-cell-soma
#15
Atsushi Saito, Longjie Cai, Koji Matsuhisa, Yosuke Ohtake, Masayuki Kaneko, Soshi Kanemoto, Rie Asada, Kazunori Imaizumi
Unfolded protein response (UPR) has roles not only in resolving the accumulation of unfolded proteins owing to endoplasmic reticulum (ER) stress, but also in regulation of cellular physiological functions. ER stress transducers providing the branches of UPR signaling are known to localize in distal dendritic ER of neurons. These reports suggest that local activation of UPR branches may produce integrated outputs for distant communication, and allow regulation of local events in highly polarized neurons. Here, we demonstrated that synaptic activity- and brain-derived neurotrophic factor (BDNF)-dependent local activation of UPR signaling could be associated with dendritic functions through retrograde signal propagation by using murine neuroblastoma cell line, Neuro-2A and primary cultured hippocampal neurons derived from postnatal day 0 litter C57BL/6 mice...
September 16, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28920939/imaging-and-tuning-polarity-at-srtio3-domain%C3%A2-walls
#16
Yiftach Frenkel, Noam Haham, Yishai Shperber, Christopher Bell, Yanwu Xie, Zhuoyu Chen, Yasuyuki Hikita, Harold Y Hwang, Ekhard K H Salje, Beena Kalisky
Electrostatic fields tune the ground state of interfaces between complex oxide materials. Electronic properties, such as conductivity and superconductivity, can be tuned and then used to create and control circuit elements and gate-defined devices. Here we show that naturally occurring twin boundaries, with properties that are different from their surrounding bulk, can tune the LaAlO3/SrTiO3 interface 2DEG at the nanoscale. In particular, SrTiO3 domain boundaries have the unusual distinction of remaining highly mobile down to low temperatures, and were recently suggested to be polar...
September 18, 2017: Nature Materials
https://www.readbyqxmd.com/read/28920916/monovacancy-paramagnetism-in-neutron-irradiated-graphite-probed-by-sup-13-sup-c-nmr
#17
Zhi Tao Zhang, C Xu, Daryna Dmytriieva, Sebastian Molatta, J Wosnitza, Y T Wang, Manfred Helm, Shengqiang Zhou, Hannes Kuehne
We report on the magnetic properties of monovacancy defects in neutron-irradiated graphite, probed by $^{13}$C nuclear magnetic resonance spectroscopy. The bulk paramagnetism of the defect moments is revealed by the temperature dependence of the NMR frequency shift and spectral linewidth, both of which follow a Curie behavior, in agreement with measurements of the macroscopic magnetization. Compared to pristine graphite, the fluctuating hyperfine fields generated by the defect moments lead to an enhancement of the $^{13}$C nuclear spin-lattice relaxation rate $1/T_{1}$ by about two orders of magnitude...
September 18, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28920862/enhanced-endothelium-epithelial-sodium-channel-signaling-prompts-left-ventricular-diastolic-dysfunction-in-obese-female-mice
#18
Guanghong Jia, Javad Habibi, Annayya R Aroor, Michael A Hill, Vincent G DeMarco, Li E Lee, Lixin Ma, Brady J Barron, Adam Whaley-Connell, James R Sowers
OBJECTIVE: Enhanced activation of cell specific mineralocorticoid receptors (MRs) in obesity plays a key role in the development of cardiovascular disease including cardiac diastolic dysfunction as a critical prognosticator. Our previous investigations demonstrated that selective endothelium MR activation promotes a maladaptive inflammatory response and fibrosis in cardiovascular tissue in female mice fed a western diet (WD), and this was associated with expression and activation of the epithelial sodium channel on the surface of endothelial cells (EnNaC)...
September 8, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28920853/flavobacterium-chuncheonense-sp-nov-and-flavobacterium-luteum-sp-nov-isolated-from-a-freshwater-lake
#19
Miri Park, Gi Gyun Nam, Suhyun Kim, Hyoung Tae Jeon, Yochan Joung, Jang-Cheon Cho
Two Gram-staining-negative, orange coloured, non-motile, rod-shaped bacterial strains, designated strains IMCC26013T and IMCC26026T, were isolated from a freshwater sample collected from Lake Soyang in Korea. The 16S rRNA gene-based phylogenetic analyses showed that both strains belonged to the genus Flavobacterium and that strains IMCC26013T and IMCC26026T were most closely related to Flavobacterium psychrophilum (96.5 %) and Flavobacterium myungsuense (97.7 %), respectively. DNA G+C contents of strains IMCC26013T and IMCC26026T were 37...
September 18, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28920851/loktanella-acticola-sp-nov-isolated-from-seawater
#20
Sooyeon Park, Su Jung Choi, Sung-Min Won, Jung-Hoon Yoon
A Gram-stain-negative, aerobic, non-motile and coccoid, ovoid or rod-shaped bacterial strain, designated OISW-6T, was isolated from seawater near Oido, a South Korean island, and subjected to a polyphasic taxonomic study. Strain OISW-6T grew optimally at 25 °C, at pH 7.0-8.0 and in the presence of 2.0-3.0 % (w/v) NaCl. The phylogenetic trees based on 16S rRNA gene sequences showed that strain OISW-6T fell within the clade comprising the type strains of Loktanella species. Strain OISW-6T exhibited 16S rRNA gene sequence similarity values of 97...
September 18, 2017: International Journal of Systematic and Evolutionary Microbiology
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