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https://www.readbyqxmd.com/read/27894853/concurrent-carpal-tunnel-syndrome-and-pronator-syndrome-a-retrospective-study-of-21-cases
#1
Chih-Wei Hsiao, Jui-Tein Shih, Sheng-Tsai Hung
PURPOSE: Concurrent carpal tunnel syndrome and pronator syndrome are rarely considered and the proximal compression sites are easily overlooked. We retrospectively studied 21 concurrent cases in our series from 2009 to 2015 and report the results. PATIENTS AND METHODS: The typical symptoms were pain, tingling, and numbness of the radial 3½ digits. If paresthesia involved the thenar eminence and proximal forearm pain was noted in cases of carpal tunnel syndrome, carpal tunnel syndrome combined with pronator syndrome was considered...
November 25, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27891703/an-investigation-into-the-inhibitory-function-of-serotonin-in-diffuse-noxious-inhibitory-controls-in-the-neuropathic-rat
#2
K Bannister, S Lockwood, L Goncalves, R Patel, A H Dickenson
BACKGROUND: Following neuropathy α2-adrenoceptor-mediated diffuse noxious inhibitory controls (DNIC), whereby a noxious conditioning stimulus inhibits the activity of spinal wide dynamic range (WDR) neurons, are abolished, and spinal 5-HT7 receptor densities are increased. Here, we manipulate spinal 5-HT content in spinal nerve ligated (SNL) animals and investigate which 5-HT receptor mediated actions predominate. METHODS: Using in vivo electrophysiology we recorded WDR neuronal responses to von frey filaments applied to the hind paw before, and concurrent to, a noxious ear pinch (the conditioning stimulus) in isoflurane-anaesthetised rats...
November 28, 2016: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/27858573/multiple-nerve-and-tendon-transfers-a-new-strategy-for-restoring-hand-function-in-a-patient-with-c7-t1-brachial-plexus-avulsions
#3
Bin Xu, Zhen Dong, Cheng-Gang Zhang, Yu-Dong Gu
C7-T1 brachial plexus palsies result in a loss of finger motion and hand function. The authors have observed that finger flexion motion can be recovered after a brachialis motor branch transfer. However, finger flexion strength after this procedure merely corresponds to Medical Research Council Grades M2-M3, lowering the grip strength and practical value of the reconstructed hand. Therefore, they used 2 donor nerves and accomplished double nerve transfers for stronger finger flexion. In a patient with a C7-T1 brachial plexus injury, they transferred the pronator teres branch to the anterior interosseous nerve and the brachialis motor branch to the flexor digitorum superficialis branch for reinnervation of full finger flexors...
November 18, 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27857760/galanin-and-its-receptor-system-promote-the-repair-of-injured-sciatic-nerves-in-diabetic-rats
#4
Xiao-Feng Xu, Dan-Dan Zhang, Jin-Chi Liao, Li Xiao, Qing Wang, Wei Qiu
Various studies have reported that galanin can promote axonal regeneration of dorsal root ganglion neurons in vitro and inhibit neuropathic pain. However, little is known about its effects on diabetic peripheral neuropathy, and in vivo experimental data are lacking. We hypothesized that repeated applications of exogenous galanin over an extended time frame may also repair nerve damage in diabetic peripheral neuropathy, and relieve pain in vivo. We found that neuropathic pain occurred in streptozotocin-induced diabetic rats and was more severe after sciatic nerve pinch injury at 14 and 28 days than in diabetic sham-operated rats...
September 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/27796190/postoperative-physical-therapy-management-of-tendon-transfer-for-digital-wrist-extension-due-to-multifocal-motor-neuropathy
#5
Steve Volpe
Study Design Case report. Background Multifocal motor neuropathy is a progressive motor nerve disorder characterized by muscle weakness in the extremities. Muscle imbalance and weakness can become so severe that the involved extremity can be rendered nonfunctional. The purpose of this case report is to describe the physical therapy postoperative management of a patient who underwent a multiple tendon transfer to correct the loss of digital/wrist extension of the right upper extremity. Case Description A 38-year-old woman with a medical diagnosis of multifocal motor neuropathy, which caused muscle imbalance and weakness in the right hand, underwent a multiple tendon transfer to correct the loss of digit and wrist extension...
December 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/27781978/modified-suzuki-frame-for-the-treatment-of-difficult-rolando-fractures
#6
T Giesen, L Neukom, R Fakin, V Beckamm-Fries, M Calcagni
Fifteen consecutive patients with severely comminuted Rolando fractures were treated by closed reduction and fixation with a modified Suzuki frame without rubber bands, followed by immediate mobilization. All the fractures healed within 5 weeks. At 3 months, no rotational deformity was observed. The Kapandji score was equal that of the contralateral thumb in eight cases. No residual pain was recorded. Grip strength was 78% and pinch strength was 78% of the contralateral hand. One patient needed the frame tension modified...
October 2016: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/27751716/recurrent-cubital-tunnel-syndrome-treated-with-revision-neurolysis-and-amniotic-membrane-nerve-wrapping
#7
Michael P Gaspar, Hesham M Abdelfattah, Ian W Welch, Michael M Vosbikian, Patrick M Kane, Mark S Rekant
BACKGROUND: Perineural scarring of the ulnar nerve is a predominant cause of symptom recurrence after surgical treatment for primary cubital tunnel syndrome (CuTS). We report our preliminary experience in revision ulnar nerve decompression and nerve wrapping with an amniotic membrane allograft adhesion barrier for treatment of recurrent CuTS. METHODS: We performed a retrospective review with prospective follow-up of patients with recurrent CuTS who were treated with revision neurolysis with amniotic membrane nerve wrapping...
October 14, 2016: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/27729812/dorsal-clitoral-nerve-injury-following-transobturator-midurethral-sling
#8
Chailee F Moss, Lynn A Damitz, Richard H Gracely, Alice C Mintz, Denniz A Zolnoun, A Lee Dellon
INTRODUCTION: Transobturator slings can be successfully used to treat stress urinary incontinence and improve quality of life through a minimally invasive vaginal approach. Persistent postoperative pain can occur and pose diagnostic and therapeutic dilemmas. Following a sling procedure, a patient complained of pinching clitoral and perineal pain. Her symptoms of localized clitoral pinching and pain became generalized over the ensuing years, eventually encompassing the entire left vulvovaginal region...
2016: Journal of Pain Research
https://www.readbyqxmd.com/read/27677020/relation-between-prehension-strength-dexterity-and-axonal-loss-in-a-charcot-marie-tooth-1a-population
#9
Isabelle Conforto, Emmanuel Coudeyre
OBJECTIVE: To evaluate the relation between prehension strength, dexterity and axonal loss in a same cohort of CMT1A patients with valid tools. CMT1A is the most common form of hereditary neuropathy. The upper limb impairment creates a weakness of intrinsic hand muscles, an opposition, prehension strength and axonal loss. MATERIALS/PATIENTS AND METHODS: Patients were recruited from November 2012 to November 2014 by Physicals Rehabilitation Medicine and Neurologicals consultations of Clermont Ferrand's University Hospital...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27650422/central-neural-alterations-predominate-in-an-insect-model-of-nociceptive-sensitization
#10
Dennis R Tabuena, Allan Solis, Ken Geraldi, Christopher A Moffatt, Megumi Fuse
Many organisms respond to noxious stimuli with defensive maneuvers. This is noted in the hornworm, Manduca sexta, as a defensive strike response. After tissue damage, organisms typically display sensitized responses to both noxious or normally innocuous stimuli. To further understand this phenomenon, we used novel in situ and in vitro preparations based on paired extracellular nerve recordings and videography to identify central and peripheral nerves responsible for nociception and sensitization of the defensive behavior in M...
September 21, 2016: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/27566324/effective-mechanism-for-synthesis-of-neurotransmitter-glutamate-and-its-loading-into-synaptic-vesicles
#11
Kouji Takeda, Tetsufumi Ueda
Glutamate accumulation into synaptic vesicles is a pivotal step in glutamate transmission. This process is achieved by a vesicular glutamate transporter (VGLUT) coupled to v-type proton ATPase. Normal synaptic transmission, in particular during intensive neuronal firing, would demand rapid transmitter re-filling of emptied synaptic vesicles. We have previously shown that isolated synaptic vesicles are capable of synthesizing glutamate from α-ketoglutarate (not from glutamine) by vesicle-bound aspartate aminotransferase for immediate uptake, in addition to ATP required for uptake by vesicle-bound glycolytic enzymes...
August 26, 2016: Neurochemical Research
https://www.readbyqxmd.com/read/27454516/lipofibromatous-hamartoma-of-the-median-and-ulnar-nerves-at-the-ipsilateral-wrist
#12
Sho Kohyama, Toshikazu Tanaka, Eriko Okano, Takaji Yanai, Naoyuki Ochiai
Lipofibromatous hamartoma (LFH) is a rare condition of the peripheral nerves that typically affects the median nerve. To the best of our knowledge, this is the first report of LFH of both, the median and ulnar nerves, at the wrist of a 63-year-old female patient. The patient presented to our hospital with a 40-year history of pain, numbness, and dysesthesia affecting all fingers of her left hand. Atrophy of the thenar muscles and the first dorsal interosseous was observed upon physical examination. Imaging studies and a surgery revealed that the patient's median and ulnar nerves were significantly enlarged, confirming the LFH diagnosis...
February 2016: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/27387080/ulnar-nerve-tendon-transfers-for-pinch
#13
REVIEW
Shane Cook, R Glenn Gaston, Gary M Lourie
Power and tip pinch are an integral part of intrinsic hand function that can be significantly compromised with dysfunction of the ulnar nerve. Loss of power pinch is one component that can significantly affect an individual's ability to perform simple daily tasks. Tip pinch is less affected, as this task has significant contributions from the median nerve. To restore power pinch, the primary focus must be on restoring the action of the adductor pollicis primarily, and if indicated the first dorsal interosseous muscle and flexor pollicis brevis...
August 2016: Hand Clinics
https://www.readbyqxmd.com/read/27387079/a-comprehensive-guide-on-restoring-grasp-using-tendon-transfer-procedures-for-ulnar-nerve-palsy
#14
REVIEW
Rafael J Diaz-Garcia, Kevin C Chung
Ulnar nerve paralysis results in classic stigmata, including weakness of grasp and pinch, poorly coordinated flexion, and clawing of digits. Restoration of grasp is a key portion of the reconstructive efforts after loss of ulnar nerve function. Improving flexion at the metacarpophalangeal joint can be done by static and dynamic means, although only the latter can improve interphalangeal extension. Deformity and digital posture are more predictably corrected with surgical intervention. Loss of strength from intrinsic muscle paralysis cannot be fully restored with tendon transfer procedures...
August 2016: Hand Clinics
https://www.readbyqxmd.com/read/27367447/development-of-kinematic-graphs-of-median-nerve-during-active-finger-motion-implications-of-smartphone-use
#15
Hoi-Chi Woo, Peter White, Ho-Kwan Ng, Christopher W K Lai
BACKGROUND: Certain hand activities cause deformation and displacement of the median nerve at the carpal tunnel due to the gliding motion of tendons surrounding it. As smartphone usage escalates, this raises the public's concern whether hand activities while using smartphones can lead to median nerve problems. OBJECTIVE: The aims of this study were to 1) develop kinematic graphs and 2) investigate the associated deformation and rotational information of median nerve in the carpal tunnel during hand activities...
2016: PloS One
https://www.readbyqxmd.com/read/27352836/surgical-treatment-for-far-out-syndrome-associated-with-abnormal-fusion-of-the-l5-vertebral-corpus-and-l4-hemivertebra-a-case-report
#16
Shohei Ise, Koki Abe, Sumihisa Orita, Tetsuhiro Ishikawa, Kazuhide Inage, Kazuyo Yamauchi, Miyako Suzuki, Jun Sato, Kazuki Fujimoto, Yasuhiro Shiga, Hirohito Kanamoto, Masahiro Inoue, Hideyuki Kinoshita, Kazuhisa Takahashi, Seiji Ohtori
BACKGROUND: Far-out syndrome was reported by Wiltse et al. in 1984, which is a condition characterized by L5 spinal nerve radiculopathy due to nerve compression between the L5 transverse process and sacral alar. Although many cases of far-out syndrome have been reported, to our knowledge, the present case firstly showed far-out syndrome due to assimilated L4 hemivertebra and L5 vertebra through which abnormal nerve root passed. CASE PRESENTATION: A 71-year-old man presented with left lower back pain and intermittent claudication accompanied by severe left buttock pain...
2016: BMC Research Notes
https://www.readbyqxmd.com/read/27344834/-discussion-on-different-methods-of-painless-needle-insertion-based-on-positions
#17
Chao Chen, Xuemin Shi
Based on multiple painless needle insertion skills in clinic combined with own experience, the authors propose the opinion that different painless needle insertion methods need to be used according to the positions where acupoints are. The appropriate needle insertion mean must be selected in accord with the anatomical characteristic of acupoint position, namely, tapping insertion is applied in scalp part, skin-pinching up needle insertion is used in forehead and superficial nerve trunk, fingernail-pressure needle insertion in ocular region and positions where large blood vessels distribute, flying acupuncture insertion in face and finger tip, vibrating needle in occipitonuchal region, quivering insertion in abdomen, quick pricking by single hand in the four limbs and back, and chop acupuncture in palm and pelma...
March 2016: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/27316447/nuclear-factor-erythroid-2-related-factor-2-antibody-attenuates-thermal-hyperalgesia-in-the-dorsal-root-ganglion-neurochemical-changes-and-behavioral-studies-after-sciatic-nerve-pinch-injury
#18
Qiong Xiang, Chao Yu, Yao-Feng Zhu, Chun-Yan Li, Rong-Bo Tian, Xian-Hui Li
Oxidative stress is generated in several peripheral nerve injury models.Nuclear factor erythroid 2-related factor 2 (Nrf2) is activated to have a role in antioxidant effect. After nerve injury, the severely painful behavior is also performed. However, little has been explored regarding the function of Nrf2 in this painful process. Therefore, in this study, we compared the effects of Nrf2 antibody administration following sciatic nerve-pinch injury on painful behavior induced in young mice and neurochemical changes in dorsal root ganglion neurons...
August 2016: Injury
https://www.readbyqxmd.com/read/27278084/nerve-crush-but-not-displacement-induced-stretch-of-the-intra-arachnoidal-facial-nerve-promotes-facial-palsy-after-cerebellopontine-angle-surgery
#19
Habib Bendella, Derald E Brackmann, Roland Goldbrunner, Doychin N Angelov
Little is known about the reasons for occurrence of facial nerve palsy after removal of cerebellopontine angle tumors. Since the intra-arachnoidal portion of the facial nerve is considered to be so vulnerable that even the slightest tension or pinch may result in ruptured axons, we tested whether a graded stretch or controlled crush would affect the postoperative motor performance of the facial (vibrissal) muscle in rats. Thirty Wistar rats, divided into five groups (one with intact controls and four with facial nerve lesions), were used...
October 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/27264897/a-structured-literature-synthesis-of-wrist-outcome-measures-an-evidence-based-approach-to-determine-use-among-common-wrist-diagnoses
#20
Gwen Weinstock-Zlotnick, Saurabh P Mehta
STUDY DESIGN: Structured literature synthesis. INTRODUCTION: Hand therapists and researchers have numerous options when selecting outcome measures for patients with wrist pathologies. An evidence-based approach to determining which measures are used most often can inform choices. PURPOSE OF THE STUDY: To describe how frequently outcome measures are used in recent randomized controlled trials of patients with wrist diagnoses. Identifying assessment design and related International Classification of Functioning, Disability and Health (ICF) domains provides additional consideration for selection...
April 2016: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
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