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https://www.readbyqxmd.com/read/28525486/regression-of-anterior-disk-osteophyte-complex-following-cervical-laminectomy-and-fusion-for-cervical-spondylotic-myelopathy
#1
Adedayo O Ashana, Jeremiah R Cohen, Brandon Evans, Langston T Holly
STUDY DESIGN: A retrospective case-control study. OBJECTIVE: To investigate whether posterior cervical laminectomy and fusion modifies the natural course of anterior disk-osteophyte complex in patients with multilevel cervical spondylotic myelopathy. SUMMARY OF BACKGROUND DATA: Dorsal migration of the spinal cord is the main purported mechanism of spinal cord decompression following cervical laminectomy and fusion but other potential mechanisms have received scant attention in the literature...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28523719/cardiovascular-events-associated-with-second-line-anti-diabetes-treatments-analysis-of-real-world-korean-data
#2
K H Ha, B Kim, H Choi, D J Kim, H C Kim
AIM: To compare the risks of cardiovascular disease (CVD) and all-cause mortality associated with sulfonylurea (SU), dipeptidyl peptidase-4 inhibitor (DPP4i) and thiazolidinedione (TZD) as add-on medications to metformin (MET) therapy in people with Type 2 diabetes. METHODS: We identified 40 263 individuals who used SU (n = 11 582), DPP4i (n = 26 623) or TZD (n = 2058) in addition to MET between January 2013 and June 2015 from the database of the Korean National Health Insurance, the single-payer healthcare system in South Korea...
May 19, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28512762/importance-of-group-therapeutic-support-for-family-members-of-children-with-alopecia-areata-a-cross-sectional-survey-study
#3
Kelly A Aschenbeck, Sarah L McFarland, Maria K Hordinsky, Bruce R Lindgren, Ronda S Farah
BACKGROUND/OBJECTIVES: The psychological effect of alopecia areata (AA) is well documented, but group interaction may help lessen this burden. We aimed to determine factors that draw patients with AA and their families to group events. METHODS: Surveys were administered at the annual alopecia areata bowling social in 2015 and 2016. This event is a unique opportunity for children with AA and their families to meet others with the disease and connect with local support group resources from the Minnesota branch of the National Alopecia Areata Foundation...
May 16, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28494048/satisfaction-and-patient-related-outcomes-in-128-patients-with-single-implant-crowns-in-situ-for-up-to-14-years
#4
Terry R Walton, Danielle M Layton
PURPOSE: To assess patient satisfaction and patient-related outcomes across the domains of appearance, cleansibility, and costs; the perceived value and worth when single implant crowns (SICs) had been in situ up to 14 years; whether satisfaction differed between patients; and whether certain characteristics might affect the questionnaire response rate. MATERIALS AND METHODS: Patients treated at a private prosthodontic practice between 2001 and 2014 (n = 207) who received a SIC (n = 256) were prospectively included...
May 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28483014/value-of-contrast-enhanced-ultrasound-and-conventional-ultrasound-in-the-diagnosis-of-papillary-thyroid-carcinoma-with-cervical-lymph-node-metastases
#5
Yan Zhang, Yukun Luo, Mingbo Zhang, Ming Yang, Ying Zhang, Junlai Li, Jie Tang
Objective To compare the ultrasound features of papillary thyroid carcinoma with or without cervical lymph node metastasis (LNM). Methods Patients suspected of thyroid cancer underwent the conventional ultrasound and contrast-enhanced ultrasound (CEUS) examinations. Patients' age,sex,and ultrasound characteristics of lesions were recorded. With the surgical pathology as the golden standard,the ultrasound features were compared between the cervical LNM group and non-LNM group. Results Of 144 patients,51 had cervical LNM and 93 did not...
April 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28467193/a-global-comprehensive-review-of-economic-interventions-to-prevent-intimate-partner-violence-and-hiv-risk-behaviours
#6
Andrew Gibbs, Jessica Jacobson, Alice Kerr Wilson
BACKGROUND: Intimate partner violence (IPV) and HIV are co-occurring global epidemics, with similar root causes of gender and economic inequalities. Economic interventions have become a central approach to preventing IPV and HIV. OBJECTIVE/METHODS: We undertook a comprehensive scoping review of published evaluations of economic interventions that sought to prevent IPV and/or HIV risk behaviours. RESULTS: Forty-five separate analyses of interventions met our criteria...
January 2017: Global Health Action
https://www.readbyqxmd.com/read/28467159/an-event-level-analysis-of-the-interpersonal-factors-associated-with-condomless-anal-sex-among-gay-bisexual-and-other-men-who-have-sex-with-men-msm-with-online-met-partners
#7
Kiffer G Card, Nathan J Lachowsky, Zishan Cui, Susan Shurgold, Heather L Armstrong, Ashleigh J Rich, Jamie I Forrest, Maya Gislason, David M Moore, Eric A Roth, Robert S Hogg
The interpersonal determinants of condomless anal sex (CAS) within online-initiated sexual relationships remain poorly understood. Therefore, respondent-driven sampling was used to recruit a prospective cohort of sexually active gay, bisexual, and other men who have sex with men (MSM), aged ≥ 16 years in Vancouver, Canada. Follow-up occurred every 6 months, up to seven visits; at each visit participants reported their last sexual encounter with their five most recent partners. Stratified by self-reported HIV status, individual-level, interpersonal, and situational covariates of event-level CAS with partners met online were modeled using generalized estimating equations (GEE)...
April 2017: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/28460334/maximal-exhaustive-treadmill-test-features-in-patients-with-temporal-lobe-epilepsy-search-for-sudden-unexpected-death-biomarkers
#8
Guilherme L Fialho, Arthur G Pagani, Roger Walz, Peter Wolf, Katia Lin
Autonomic dysfunction may account for sudden unexpected death in patients with epilepsy (PWE). On the other hand, low cardiovascular fitness, which may affect autonomic function, is a risk factor for sudden death and all-cause mortality in the general population. Little is known about autonomic variables and cardiovascular response to exercise in PWE. We submitted thirty consecutive PWE with no known cardiovascular diseases to maximal treadmill test, comparing them with matched controls. All individuals were submitted to clinical assessment, 12-lead electrocardiogram (ECG) and echocardiogram to exclude cardiovascular disease...
April 24, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28456472/a-review-of-risk-behaviors-for-hiv-infection-by-men-who-have-sex-with-men-through-geosocial-networking-phone-apps
#9
Artur Acelino Francisco Luz Nunes Queiroz, Álvaro Francisco Lopes de Sousa, Telma Maria Evangelista de Araújo, Francisco Braz Milanez de Oliveira, Maria Eliete Batista Moura, Renata Karina Reis
The purpose of our review was to analyze the relationship between the use of geosocial networking phone apps and risk behaviors for HIV infection in men who have sex with men (MSM). The review was guided by the question: Does the use of geosocial networking apps to find sex partners increase risk behaviors for HIV infection by MSM? We searched the databases PubMed, Web of Science, CINAHL, and LILACS, considering primary studies published up to December 2015, without any time restraint. All 14 studies that met our search criteria analyzed sexual behaviors in relation to sociocultural and economic characteristics, number of partners, unprotected anal sex, drug use, HIV testing, risk management measures, and the presence of other sexually transmitted diseases...
April 4, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/28455621/characteristics-of-advanced-gastric-cancer-with-negative-or-only-perigastric-lymph-node-metastasis-in-elderly-patients
#10
Hajime Fujishima, Yoshitake Ueda, Norio Shiraishi, Takao Hara, Michihiro Ichimanda, Yuki Shitomi, Hidefumi Shiroshita, Tsuyoshi Etoh, Masafumi Inomata
OBJECTIVES: After gastrectomy with extended lymph node (LN) dissection, the damage of celiac plexus seems to cause of disorder of eating habits. To clarify the indication of gastrectomy with limited LN dissection for elderly patients, the pathological characteristics of advanced gastric cancer in elderly patients were examined in this study. METHODS: Forty-seven patients aged ≥80 years with advanced gastric cancer (deeper than pT2) who underwent curative gastrectomy from 1998 to 2015 were enrolled...
April 28, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28453243/factors-associated-with-retention-in-option-b-in-malawi-a-case-control-study
#11
Risa M Hoffman, Khumbo Phiri, Julie Parent, Jonathan Grotts, David Elashoff, Paul Kawale, Sara Yeatman, Judith S Currier, Alan Schooley
INTRODUCTION: There are limited data on factors associated with retention in Option B+. We sought to explore the characteristics of women retained in Option B+ in Malawi, with a focus on the role of HIV disclosure, awareness of partner HIV status, and knowledge around the importance of Option B+ for maternal-child health. Methods We performed a case-control study of HIV-infected women in Malawi initiated on antiretroviral therapy (ART) under Option B+. Cases were enrolled if they met criteria for default from Option B+ (out of ART for >60 days), and controls were enrolled in approximately 3:1 ratio if they were retained in care for at least 12 months...
April 27, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28449887/sleep-deficiency-on-school-days-in-icelandic-youth-as-assessed-by-wrist-accelerometry
#12
Vaka Rognvaldsdottir, Sigridur L Gudmundsdottir, Robert J Brychta, Soffia M Hrafnkelsdottir, Sunna Gestsdottir, Sigurbjorn A Arngrimsson, Kong Y Chen, Erlingur Johannsson
AIMS: The purpose of this study was to objectively measure, with wrist-worn actigraphy, free-living sleeping patterns in Icelandic adolescents, and to compare sleep duration, sleep quality and clock times between school days (SchD) and non-school days (NSchD) and the association between sleep and body mass index (BMI). METHODS: A cross-sectional study on 15.9-year-old (±0.3) adolescents from six schools in Reykjavík, Iceland, took place in the spring of 2015. Free-living sleep was measured on 301 subjects (122 boys and 179 girls) over seven days using wrist-worn actigraphy accelerometers...
May 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28445149/elevated-cd147-expression-is-associated-with-shorter-overall-survival-in-non-small-cell-lung-cancer
#13
Xiaojun Zhang, Tian Tian, Xiaofeng Zhang, Changting Liu, Xiangqun Fang
A number of studies have reported on the prognostic role of CD147 expression in non-small cell lung cancer (NSCLC); however, the results remain controversial. This study aims to investigate the impact of CD147 on the prognosis of NSCLC by means of a meta-analysis. A literature search was performed for relevant studies published before October 29, 2016. The hazard ratios (HRs), odds ratios (ORs), and 95% confidence intervals (CIs) were calculated as effective measures. Sensitivity analysis and publication bias examination were also conducted...
April 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28393706/ultrasound-assisted-catheter-directed-thrombolysis-in-high-risk-and-intermediate-high-risk-pulmonary-embolism-a-meta-analysis
#14
Cihangir Kaymaz, Özgür Yaşar Akbal, Ibrahim Halil Tanboğa, Aykun Hakgör, Fatih Yilmaz, Selçuk Öztürk, Nertila Poçi, Sevim Türkday, Nihal Özdemir, Stavros Konstantinides
Catheter-directed Ultrasound-Assisted Thrombolysis (USAT) is a novel technology providing a high efficacy with a reduced bleeding risk in patients with pulmonary embolism (PE). We performed a meta-analysis based on presented or published PE series in which USAT was utilized. We searched the MEDLINE, EMBASE and the Cochrane Library for trials published up to December 2015. The primary outcomes were mean pulmonary artery pressure (PAMP), right to left ventricle diameter ratio (RV/LV ratio) and computed tomography (CT) obstruction score...
April 4, 2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/28392293/burden-and-treatment-patterns-of-advanced-basal-cell-carcinoma-among-commercially-insured-patients-in-a-united-states-database-from-2010-to-2014
#15
Michael Migden, Jipan Xie, Jin Wei, Wenxi Tang, Vivian Herrera, Jacqueline B Palmer
BACKGROUND: The burden of advanced basal cell carcinoma (aBCC) is not fully understood. OBJECTIVE: To compare BCC disease burden and treatment patterns for aBCC with those for non-aBCC. METHODS: A retrospective, insurance claims-based study design was used. Adults with ≥2 claims associated with a BCC diagnosis (ICD-9-CM 173.x1) separated by ≥30 days on or after October 1, 2011, were classified as aBCC or non-aBCC by using an algorithm based on metastasis diagnosis, radiation therapy use, and medical oncologist/other specialist use...
April 6, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28391775/patterns-of-care-and-outcomes-of-patients-with-metastatic-soft-tissue-sarcoma-in-a-real-life-setting-the-metasarc-observational-study
#16
Marion Savina, Axel Le Cesne, Jean-Yves Blay, Isabelle Ray-Coquard, Olivier Mir, Maud Toulmonde, Sophie Cousin, Philippe Terrier, Dominique Ranchere-Vince, Pierre Meeus, Eberhard Stoeckle, Charles Honoré, Paul Sargos, Marie-Pierre Sunyach, Cécile Le Péchoux, Antoine Giraud, Carine Bellera, François Le Loarer, Antoine Italiano
BACKGROUND: Well-designed observational studies of individuals with rare tumors are needed to improve patient care, clinical investigations, and the education of healthcare professionals. METHODS: The patterns of care, outcomes, and prognostic factors of a cohort of 2225 patients with metastatic soft tissue sarcomas who were diagnosed between 1990 and 2013 and documented in the prospectively maintained database of the French Sarcoma Group were analyzed. RESULTS: The median number of systemic treatments was 3 (range, 1-6); 27% of the patients did not receive any systemic treatment and 1054 (49%) patients underwent locoregional treatment of the metastasis...
April 10, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28385570/-why-is-it-important-to-differentiate-trichoblastic-carcinomas-ct-from-basal-cell-carcinomas-cbc-about-21-cases
#17
M Thomas, C Bruant-Rodier, F Bodin, B Cribier, M Huther, C Dissaux
Trichoblastic carcinoma is a rare epithelial malignant epithelial tumor, its diagnosis is difficult and the therapeutic management is non-consensual. This retrospective study, carried out between 2009 and 2015, covered 21 cases and analyzed the diagnostic and therapeutic characteristics of trichoblastic carcinomas. Sex ratio is 2. Trichoblastic carcinoma predominated in the face (65% of cases), particularly in perinasal (30% of cases). Its clinical presentation is in 95% of cases as basal cell carcinoma, which is the first clinical diagnosis evoked...
April 3, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28333365/clozapine-combined-with-different-antipsychotic-drugs-for-treatment-resistant-schizophrenia
#18
REVIEW
Sarah Barber, Uwaila Olotu, Martina Corsi, Andrea Cipriani
BACKGROUND: Between 40% and 70% of people with treatment-resistant schizophrenia do not respond to clozapine, despite adequate blood levels. For these people, a number of treatment strategies have emerged, including the prescription of a second anti-psychotic drug in combination with clozapine. OBJECTIVES: To determine the clinical effects of various clozapine combination strategies with antipsychotic drugs in people with treatment-resistant schizophrenia both in terms of efficacy and tolerability...
March 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28319239/mobile-health-interventions-for-improving-health-outcomes-in-youth-a-meta-analysis
#19
David A Fedele, Christopher C Cushing, Alyssa Fritz, Christina M Amaro, Adrian Ortega
Importance: Mobile health interventions are increasingly popular in pediatrics; however, it is unclear how effective these interventions are in changing health outcomes. Objective: To determine the effectiveness of mobile health interventions for improving health outcomes in youth 18 years or younger. Data Sources: Studies published through November 30, 2016, were collected through PubMed, Cumulative Index to Nursing and Allied Health Literature, Educational Resources Information Center, and PsychINFO...
May 1, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28314804/stereological-monitoring-of-mouse-lung-alveolarization-from-the-early-post-natal-period-to-adulthood
#20
Agnieszka Pozarska, José Alberto Rodríguez-Castillo, David Emanuel Surate Solaligue, Aglaia Ntokou, Philipp Rath, Ivana Mižíková, Alicia Madurga, Konstantin Mayer, István Vadász, Susanne Herold, Katrin Ahlbrecht, Werner Seeger, Rory E Morty
Post-natal lung maturation generates a large number of small alveoli, with concomitant thinning of alveolar septal walls, generating a large gas exchange surface area but minimizing the distance traversed by the gases. This demand for a large and thin gas exchange surface area is not met in disorders of lung development, such as bronchopulmonary dysplasia (BPD), histopathologically characterized by fewer, larger alveoli; and thickened alveolar septal walls. Diseases such as BPD are often modeled in the laboratory mouse to better understand disease pathogenesis, or develop new interventional approaches...
March 17, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
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