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Guido Wolferts, Daniel Schicke, K-Wolfgang Delank
Aim of the present study is to evaluate the long term results of ossiculoplasty using titanium clip prosthesis. A retrospective analysis with prospective follow-up has been done including for all patients who had a Clip-PORP implanted between the years 2002-2013. Following this, audiometric hearing results were measured with clinical examination including otoscopy and quality of life evaluation using Glasgow benefit inventory. 48 patients (51 ears, 29 men, 19 women, average age 44.1 years) received followed up after an average duration of 6...
May 12, 2017: Laryngo- Rhino- Otologie
John M Carter, Stephen R Hoff
OBJECTIVE: To describe our indications, findings, and outcomes for transcanal endoscopic middle ear exploration in pediatric patients with conductive hearing loss of unknown etiology, without effusions. METHODS: Prospective case series for all pediatric patients undergoing totally endoscopic transcanal middle ear exploration between April 2012 and October 2015 at a pediatric tertiary care referral hospital. Demographic data, operative findings, and hearing results were reviewed...
May 2017: International Journal of Pediatric Otorhinolaryngology
Cagatay Han Ulku
The objective of this study was to analyze the results of endoscopy-assisted ear surgery for the treatment of chronic otitis media with cholesteatoma, adhesion, or retraction pockets.Fifty-one patients who underwent oto-endoscopy-assisted canal wall up tympanomastoid surgery and/or limited anterior atticotomy with tympanoplasty for chronic otitis media with cholesteatoma, adhesion, or retraction pocket from 2006 to 2013 have been included in this study. Eradication of the disease from the middle ear and mastoid air cells was achieved by combination of the oto-microscobic and oto-endoscopic approaches...
June 2017: Journal of Craniofacial Surgery
Ahmet Mutlu, Özlem Topdağ, Murat Topdağ, Mete İşeri, Selvet Erdoğan
OBJECTIVE: The aim of this study was to compare the hearing results of embedding the partial ossicular reconstruction prosthesis (PORP) underneath the malleus with the malleus relocation technique and tympanic membrane graft in the presence of the malleus. MATERIALS AND METHODS: A retrospective review of patient charts and audiometric results in a tertiary referral center was conducted. In total, 83 patients who underwent intact canal tympanoplasty with mastoidectomy between 2010 and 2015 were included and divided into two different groups: malleus assembly to the stapes head (MASH) and tympanic membrane assembly to the stapes head (TASH)...
March 9, 2017: Journal of International Advanced Otology
Wei Dong, Ying Tian, Xin Gao, Timothy T K Jung
HYPOTHESIS: We hypothesize that current clinical treatment strategies for the disarticulated or eroded incus have the effect of combining the incus and stapes of the human middle ear (ME) into one rigid structure, which, while capable of adequately transmitting lower-frequency sounds, fails for higher frequencies. BACKGROUND: ME damage causes conductive hearing loss (CHL) and while great progress has been made in repairing or reconstructing damaged MEs, the outcomes are often far from ideal...
April 2017: Otology & Neurotology
Jeanette Hess-Erga, Bart Lambertus Henricus Jozef Engelen, Flemming Slinning Vassbotn
The most common technique in sound restoration of the middle ear is prosthetic surgery. Hypoventilation of the middle ear may cause adhesive otitis or atelectasis resulting in a higher risk of prosthetic extrusion rate and recurrence of the underlying cholesteatoma. We report long-term results using an island of tragal cartilage as an autologous PORP in selected patients with poor middle ear ventilation. Retrospective chart reviews were performed for procedures involving 52 patients between year 2000 and 2009...
April 2017: European Archives of Oto-rhino-laryngology
Sultan Şevik Eliçora, Duygu Erdem, Aykut Erdem Dinç, Murat Damar, Sultan Bişkin
To investigate the effects of surgery type [intact canal wall (ICW) or canal wall down (CWD) mastoidectomy] and different ossiculoplasty materials on hearing outcome in single-staged cholesteatoma surgery. A retrospective case-control study. A total of 116 cases (97 adults, 29 children) underwent surgery, including ossiculoplasty, between 2012 and 2015 for cholesteatoma. Patients who had undergone surgery for the first time, and whose grafts were successful, were included in the study. Patients with adhesive otitis media, unsuccessful grafts, revision and recurrent cases, radical mastoidectomy, and craniofacial anomalies were excluded...
February 2017: European Archives of Oto-rhino-laryngology
Maxence S Vincent, Eric Durand, Eric Cascales
The Type IX secretion system (T9SS) is a versatile multi-protein complex restricted to bacteria of the Bacteriodetes phylum and responsible for the secretion or cell surface exposition of diverse proteins that participate to S-layer formation, gliding motility or pathogenesis. The T9SS is poorly characterized but a number of proteins involved in the assembly of the secretion apparatus in the oral pathogen Porphyromonas gingivalis have been identified based on genome substractive analyses. Among these proteins, PorY, and PorX encode typical two-component system (TCS) sensor and CheY-like response regulator respectively...
2016: Frontiers in Cellular and Infection Microbiology
Dhana G Gorasia, Paul D Veith, Eric G Hanssen, Michelle D Glew, Keiko Sato, Hideharu Yukitake, Koji Nakayama, Eric C Reynolds
The type IX secretion system (T9SS) has been recently discovered and is specific to Bacteroidetes species. Porphyromonas gingivalis, a keystone pathogen for periodontitis, utilizes the T9SS to transport many proteins including the gingipain virulence factors across the outer membrane and attach them to the cell surface via a sortase-like mechanism. At least 11 proteins have been identified as components of the T9SS including PorK, PorL, PorM, PorN and PorP, however the precise roles of most of these proteins have not been elucidated and the structural organization of these components is unknown...
August 2016: PLoS Pathogens
Bo Yang, Xuejun Jiang, Ning Yang, Lian Hui, Buquan Wang, Yu Sun
OBJECTIVE: To investigate the efficacy of operations of acquired middle ear cholesteatoma. METHODS: Retrospectively analyzed clinical data of 102 patients whom received tympanoplasty with CWU or CWD with mastoid obliteration in our hospital between January 2014 and December 2014. Patients were divided into different groups according to types of the cholesteatoma as well as the different surgical procedures. Patients were followed up for 12-24 months, the pre and post-operative PTA was performed and evaluated...
May 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Volkan Gungor, Gamze Atay, M Demir Bajin, Mehmet Yarali, Sarp Sarac, Levent Sennaroglu
OBJECTIVE: In this study, functional results of different bone cement ossiculoplasty techniques are compared. METHODS: Retrospective case review at a tertiary referral center. Patients who underwent middle ear surgery and bone cement ossiculoplasty between 2006-2012 were included. A total of 52 patients, including 30 patients with 'Incus to stapes' (Group 1) and 13 patients with 'malleus to stapes' (Group 2), five patients with 'incudoplasty + stapedotomy' (Group 3), and four patients with 'malleus to incus' (Group 4) ossiculoplasty were enrolled in the study...
September 2016: Acta Oto-laryngologica
Brendan P O'Connell, Habib G Rizk, Tanisha Hutchinson, Shaun A Nguyen, Paul R Lambert
OBJECTIVE: The primary objective is to report long-term hearing outcomes (>2 years) after titanium ossiculoplasty in patients with chronic otitis media. STUDY DESIGN: Case series with chart review. SETTING: Tertiary care hospital. SUBJECTS AND METHODS: In total, 156 patients with chronic otitis media undergoing titanium ossiculoplasty were included. The primary outcome measure was the long-term postoperative ABG. The stability of hearing over time was determined by comparing short-term and long-term postoperative air-bone gap (ABG)...
June 2016: Otolaryngology—Head and Neck Surgery
Feng Yang, Rendong Song, Yang Liu
OBJECTIVE: To explore the technique of hearing reconstruction in the cases of conductive hearing loss with malformed tympanic segment of facial nerve. METHODS: Data of 10 cases from July 2010 to March 2015 were collected.The status of tympanic segment of facial nerve, malformed ossicles and the reconstructed methods of ossicular chain were analyzed and discussed based on the embryo anatomy and surgical technique. RESULTS: All facial nerves in 10 cases were exposed and drooping to stapes or cover the oval window...
February 2, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
N Quaranta, S Taliente, F Coppola, I Salonna
Cartilage tympanoplasty is an established procedure for tympanic membrane and attic reconstruction. Cartilage has been used as an ossiculoplasty material for many years. The aim of this study was to evaluate hearing results of costal cartilage prostheses in ossicular chain reconstruction procedures in subjects operated on for middle ear cholesteatoma and to determine the presence of prognostic factors. Candidates for this study were patients affected by middle ear cholesteatoma whose ossicular chain was reconstructed with a chondroprosthesis...
October 2015: Acta Otorhinolaryngologica Italica
Kyoji Hirai, Tetsuo Kawashima, Shingo Takeuchi, Jitsuo Usuda
BACKGROUND: Postoperative recurrent pneumothorax (PORP) can arise after surgery for primary spontaneous pneumothorax (PSP) that is recurrent or involves prolonged air leakage. In this study, which included 265 patients (279 cases) with PSP who underwent surgery at our department, the percentage of patients that did not experience PORP was compared between a group that underwent bullectomy alone (group A) and a group in which the staple line and the surrounding visceral pleura were covered with a PGA sheet after bullectomy (group B) in order to study the utility of PGA sheets for preventing PORP...
November 2015: Journal of Thoracic Disease
Andrew B Baker, Brendan P O'Connell, Shaun A Nguyen, Paul R Lambert
OBJECTIVES: Inferior rotation of the stapes or a small middle ear cleft can make placement of partial ossicular replacement prostheses (PORP) challenging. This study examines outcomes of total titanium prosthesis (TORP) ossiculoplasty in such patients and compares the results to PORPs. STUDY DESIGN: Review of prospective database. SETTING: Tertiary hospital. PATIENTS: Patients with an intact/mobile stapes undergoing titanium ossicular chain reconstruction from 2002 to 2014...
December 2015: Otology & Neurotology
Allan Roux, David Bakhos, Alexandre Villeneuve, Ruben Hermann, Paul Suy, Emmanuel Lescanne, Eric Truy
INTRODUCTION: Posterior tympanotomy (PT) is often performed during the surgical management of middle ear cholesteatoma with extension in the retrotympanum area. This PT can also be used to control the right position of the ossicular prosthesis masked by the tympanic membrane reconstruction. OBJECTIVE: To compare audiologic results after ossiculoplasty performed via the outer ear canal and via the PT for patients with cholesteatoma. MATERIALS AND METHODS: Retrospective chart reviews were performed for 68 patients (68 ears) with cholesteatoma who underwent titanium ossicular prosthesis surgery between January 2007 and January 2011...
September 2015: Otology & Neurotology
Susen Lailach, Thomas Zahnert, Nikoloz Lasurashvili, Max Kemper, Thomas Beleites, Marcus Neudert
The objective of this study was to assess hearing outcome after sequential cholesteatoma surgery stratified for exclusively transcanal technique (ETC), combined transcanal and transmastoidal technique (TCM) and canal wall down surgery (CWD) and to analyze the impact of ossicular reconstruction technique (partial ossicular replacement prostheses/PORP and total ossicular replacement prostheses/TORP) on hearing outcome. This study is a retrospective case review and clinical case study conducted in a tertiary referral center...
August 2016: European Archives of Oto-rhino-laryngology
Maciej Wiatr, Agnieszka Wiatr, Jacek Składzień, Paweł Stręk
BACKGROUND: Middle ear surgery aims to eliminate pathology from the middle ear, improve drainage and ventilation of the postoperative cavity, and reconstruct the tympanic membrane and ossicles. The aim of this work is to define the factors that affect ABG (air-bone gap) and bone conduction in the patients operated on due to chronic otitis media. MATERIAL AND METHODS: A prospective analysis of patients operated on due to diseases of the middle ear during 2009-2012 was carried out...
2015: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Jong-Ik Lee, Shin-Hyuk Yoo, Chang Wook Lee, Chan Il Song, Myung Hoon Yoo, Hong Ju Park
The aim of this study was to compare the short-term audiologic results of the ossiculoplasty using partial or total ossicular replacement prostheses (PORP or TORP) made of hydroxyapatite (HA) and titanium (Ti). Fifty-two consecutive patients who underwent ossiculoplasty due to chronic otitis media with or without cholesteatoma were enrolled. Patients were assessed at 6 months postoperatively to establish short-term audiologic results. Preoperative and postoperative air-conduction and bone-conduction thresholds were measured at five frequencies: 0...
October 2015: European Archives of Oto-rhino-laryngology
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