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Badi Aldosari, Jean-Marc Thomassin
Objective: The purpose of this study is to evaluate our experience with endoscopic repair of ossicular discontinuity at the incudostapedial joint, with or without an intact stapes suprastructure, and present our hearing results. We classify results based on the causative pathology, the type of ossiculoplasty, and type of lesion. We demonstrate the ability to endoscopically place a total ossicular replacement prosthesis (TORP), measuring 4.25 mm, between the stapes footplate and the incus remnant to reestablish ossicular continuity...
September 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
Suresh Kumar, Kanak Yadav, Tarun Ojha, Abhishek Sharma, Amit Singhal, Saurabh Gakhar
Chronic suppurative otitis media, with and without cholesteatoma, frequently results in disruption of the ossicular chain. The present study was designed to compare the outcome using autologous ossicle and titanium prosthesis in two groups of suitable patients presenting with chronic suppurative otitis media for middle ear reconstructive surgeries. A prospective study done from July 2012 to December 2013, at Mahatma Gandhi Medical College and Hospital, Sitapura, Jaipur (Rajasthan). The target group included patients with chronic suppurative otitis media admitted and planned for reconstructive middle ear surgery...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
A A Majekodunmi, O A Ikotun, O D Oladokun
BACKGROUND: Postoperative residual paralysis (PORP) is a known risk factor after general anesthesia (GA) for critical respiratory events and increased postoperative morbidity. PORP is defined as a train-of-four ratio (TOFR) of <0.9 using acceleromyography (AMG). TOFR <0.9 has been associated with increased risk of aspiration, obstruction of the upper airway and an impaired hypoxic ventilatory response. AIM: The aim of this study was to determine the incidence of PORP, associated factors related with its occurrence and critical respiratory events in the postanesthesia recovery room (PAR) at our institution...
December 2017: Nigerian Journal of Clinical Practice
Ricardo Bartel, Francesc Cruellas, Miriam Hamdan, Xavier Gonzalez-Compta, Enric Cisa, Ivan Domenech, Manel Manos
OBJECTIVE: The objective of this study is to compare hearing improvements in the air-bone gap (ABG) after type III tympanoplasties, comparing between incus transposition (IT) and partial ossicular replacement prosthesis (PORP). MATERIALS AND METHODS: Publications in English were searched in PUBMED database and were systematically reviewed. A total of 14 articles were included, obtaining 1055 patients, 614 for the IT group and 441 for the PORP group. Preoperative ABG, postoperative ABG, dB gain and ABG closure rate were compared...
January 21, 2018: Acta Oto-laryngologica
Anders Niklasson, Kilian Gladiné, Anton Rönnblom, Magnus von Unge, Joris Dirckx, Krister Tano
OBJECTIVE: To compare stapes vibrations in different partial ossicular replacement prosthesis (PORP) applications. METHODS: Stapedial vibrations were measured on fresh frozen human temporal bones with laser Doppler vibrometry. Eight different types of common ossiculoplasty methods were compared regarding recovery of stapes vibrations in relation with the normal ossicular chain. The PORPs were divided into three groups: 1) PORPs with the lateral contact only with the tympanic membrane, 2) PORPs with lateral contact only to the malleus handle, and 3) PORPs with lateral contact with both the malleus handle and the tympanic membrane...
March 2018: Otology & Neurotology
Andrea Zitolo, Nastaran Ranjbar-Sahraie, Tzonka Mineva, Jingkun Li, Qingying Jia, Serban Stamatin, George F Harrington, Stephen Mathew Lyth, Petr Krtil, Sanjeev Mukerjee, Emiliano Fonda, Frédéric Jaouen
Single-atom catalysts with full utilization of metal centers can bridge the gap between molecular and solid-state catalysis. Metal-nitrogen-carbon materials prepared via pyrolysis are promising single-atom catalysts but often also comprise metallic particles. Here, we pyrolytically synthesize a Co-N-C material only comprising atomically dispersed cobalt ions and identify with X-ray absorption spectroscopy, magnetic susceptibility measurements and density functional theory the structure and electronic state of three porphyrinic moieties, CoN4 C12 , CoN3 C10,porp and CoN2 C5 ...
October 16, 2017: Nature Communications
Guido Wolferts, Daniel Schicke, K-Wolfgang Delank
Aim of the present study is to evaluate the long term results of ossiculoplasty using titanium clip prosthesis. A retrospective analysis with prospective follow-up has been done including for all patients who had a Clip-PORP implanted between the years 2002-2013. Following this, audiometric hearing results were measured with clinical examination including otoscopy and quality of life evaluation using Glasgow benefit inventory. 48 patients (51 ears, 29 men, 19 women, average age 44.1 years) received followed up after an average duration of 6...
October 2017: Laryngo- Rhino- Otologie
J S Kong, C Y Jeong, M J Shim, W J Kim, S W Yeo, S N Park
OBJECTIVE: Ossiculoplasty is a surgical procedure that recreates sound transmission of the middle ear in conductive hearing loss. Various materials have been used for ossicular reconstruction, but the most ideal material for ossiculoplasty remains controversial. The purpose of this study was to introduce a novel method of autologous ossiculoplasty, bone-cartilage composite graft (BCCG) and to compare its surgical results with different types of ossiculoplastic prostheses. STUDY DESIGN: A retrospective study was performed in a tertiary referral centre...
September 25, 2017: Clinical Otolaryngology
Brent Jerome Wilkerson, Sandra F Porps, Seilesh C Babu
OBJECTIVES: Cochlear implants have been used for many years for bilateral profound hearing loss. General longevity has continued to increase and, therefore, the age at which cochlear implants are placed has concomitantly increased. Our purpose is to determine whether outcomes and complications are significantly different in the elderly. STUDY DESIGN: Retrospective, clinical review. SETTING: Tertiary referral center, primarily ambulatory setting...
September 2017: Otology & Neurotology
Bruce Black, Ian Gutteridge
OBJECTIVE: Assessment of the outcomes of a technique of prevention of recurrent cholesteatoma in canal wall up (CWU) mastoidectomy, using titanium sheeting to repair the external auditory canal wall. PATIENTS: Sixty four cholesteatoma cases were managed during a period from 2007 to 2015. The cases were unselected; the surgery was performed by the senior author. Cholesteatoma Patterns Were: Forty two attic, nine pars tensa, seven combined attic-pars tensa, three congenital, and three other...
October 2017: Otology & Neurotology
Robert J Yawn, Jacob B Hunter, Brendan P O'Connell, George B Wanna, Daniel E Killeen, Cameron C Wick, Brandon Isaacson, Alejandro Rivas
OBJECTIVE: To evaluate the audiometric outcomes following endoscopic ossicular chain reconstruction (OCR). STUDY DESIGN: Retrospective case series. SETTING: Two tertiary referral centers. PATIENTS: Sixty two ears with ossicular discontinuity. INTERVENTION(S): Endoscopic and microscopic OCR in patients with ossicular discontinuity. MAIN OUTCOME MEASURES: Bone and air pure-tone averages (PTA), air-bone gap (ABG), and word recognition scores (WRS)...
October 2017: Otology & Neurotology
Hye Mi Ahn, Jeong Mi Bae, Min Jeong Kim, Kwon Hee Bok, Ha Young Jeong, Suk Joong Lee, Cheal Kim
A new nickel(II) porphyrin complex, [Ni(II) (porp)] (1), has been synthesized and characterized by (1) H NMR, (13) C NMR and mass spectrometry analysis. This Ni(II) porphyrin complex 1 quantitatively catalyzed the epoxidation reaction of a wide range of olefins with meta-chloroperoxybenzoic acid (m-CPBA) under mild conditions. Reactivity and Hammett studies, H2(18) O-exchange experiments, and the use of PPAA (peroxyphenylacetic acid) as a mechanistic probe suggested that participation of multiple active oxidants Ni(II) -OOC(O)R 2, Ni(IV) -Oxo 3, and Ni(III) -Oxo 4 within olefin epoxidation reactions by the nickel porphyrin complex is markedly affected by solvent polarity, concentration, and type of substrate...
July 21, 2017: Chemistry: a European Journal
Elisabeth Sterrer, Benjamin Loader
Both, PORP and incus interpositions, are valuable techniques for the reconstruction of the conductive mechanism. In our study we were able to show that, in certain aspects, the audiological outcome was better in incus remodelling reconstruction than in PORP placement. A detailed analysis of all frequencies showed significantly better results in the incus group especially for the frequencies 250Hz, 1000Hz, 2000Hz and 3000Hz. If clinical conditions warrant it, a reconstruction of the ossicular chain with incus interposition may be preferred to PORP...
July 20, 2017: Clinical Otolaryngology
Nandini Govil, Thomas M Kaffenberger, Amber D Shaffer, David H Chi
OBJECTIVE: Ossicular chain disruption in children leads to conductive hearing loss. Few studies have focused on factors influencing successful results in pediatric ossicular chain reconstruction (OCR). We aim to determine whether demographic or surgical factors affect hearing outcomes in pediatric OCR. METHODS: We conducted a retrospective chart review of 120 patients undergoing OCR at our institution, a tertiary care hospital, between 2003 and 2014, with median length of follow-up of 2...
August 2017: International Journal of Pediatric Otorhinolaryngology
Guido Wolferts, Daniel Schicke, K-Wolfgang Delank
Aim of the present study is to evaluate the long term results of ossiculoplasty using titanium clip prosthesis. A retrospective analysis with prospective follow-up has been done including for all patients who had a Clip-PORP implanted between the years 2002-2013. Following this, audiometric hearing results were measured with clinical examination including otoscopy and quality of life evaluation using Glasgow benefit inventory. 48 patients (51 ears, 29 men, 19 women, average age 44.1 years) received followed up after an average duration of 6...
May 12, 2017: Laryngo- Rhino- Otologie
John M Carter, Stephen R Hoff
OBJECTIVE: To describe our indications, findings, and outcomes for transcanal endoscopic middle ear exploration in pediatric patients with conductive hearing loss of unknown etiology, without effusions. METHODS: Prospective case series for all pediatric patients undergoing totally endoscopic transcanal middle ear exploration between April 2012 and October 2015 at a pediatric tertiary care referral hospital. Demographic data, operative findings, and hearing results were reviewed...
May 2017: International Journal of Pediatric Otorhinolaryngology
Cagatay Han Ulku
The objective of this study was to analyze the results of endoscopy-assisted ear surgery for the treatment of chronic otitis media with cholesteatoma, adhesion, or retraction pockets.Fifty-one patients who underwent oto-endoscopy-assisted canal wall up tympanomastoid surgery and/or limited anterior atticotomy with tympanoplasty for chronic otitis media with cholesteatoma, adhesion, or retraction pocket from 2006 to 2013 have been included in this study. Eradication of the disease from the middle ear and mastoid air cells was achieved by combination of the oto-microscobic and oto-endoscopic approaches...
June 2017: Journal of Craniofacial Surgery
Ahmet Mutlu, Özlem Topdağ, Murat Topdağ, Mete İşeri, Selvet Erdoğan
OBJECTIVE: The aim of this study was to compare the hearing results of embedding the partial ossicular reconstruction prosthesis (PORP) underneath the malleus with the malleus relocation technique and tympanic membrane graft in the presence of the malleus. MATERIALS AND METHODS: A retrospective review of patient charts and audiometric results in a tertiary referral center was conducted. In total, 83 patients who underwent intact canal tympanoplasty with mastoidectomy between 2010 and 2015 were included and divided into two different groups: malleus assembly to the stapes head (MASH) and tympanic membrane assembly to the stapes head (TASH)...
August 2017: Journal of International Advanced Otology
Wei Dong, Ying Tian, Xin Gao, Timothy T K Jung
HYPOTHESIS: We hypothesize that current clinical treatment strategies for the disarticulated or eroded incus have the effect of combining the incus and stapes of the human middle ear (ME) into one rigid structure, which, while capable of adequately transmitting lower-frequency sounds, fails for higher frequencies. BACKGROUND: ME damage causes conductive hearing loss (CHL) and while great progress has been made in repairing or reconstructing damaged MEs, the outcomes are often far from ideal...
April 2017: Otology & Neurotology
Jeanette Hess-Erga, Bart Lambertus Henricus Jozef Engelen, Flemming Slinning Vassbotn
The most common technique in sound restoration of the middle ear is prosthetic surgery. Hypoventilation of the middle ear may cause adhesive otitis or atelectasis resulting in a higher risk of prosthetic extrusion rate and recurrence of the underlying cholesteatoma. We report long-term results using an island of tragal cartilage as an autologous PORP in selected patients with poor middle ear ventilation. Retrospective chart reviews were performed for procedures involving 52 patients between year 2000 and 2009...
April 2017: European Archives of Oto-rhino-laryngology
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