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https://www.readbyqxmd.com/read/27837423/the-effects-of-surgery-type-and-different-ossiculoplasty-materials-on-the-hearing-results-in-cholesteatoma-surgery
#1
Sultan Şevik Eliçora, Duygu Erdem, Aykut Erdem Dinç, Murat Damar, Sultan Bişkin
To investigate the effects of surgery type [intact canal wall (ICW) or canal wall down (CWD) mastoidectomy] and different ossiculoplasty materials on hearing outcome in single-staged cholesteatoma surgery. A retrospective case-control study. A total of 116 cases (97 adults, 29 children) underwent surgery, including ossiculoplasty, between 2012 and 2015 for cholesteatoma. Patients who had undergone surgery for the first time, and whose grafts were successful, were included in the study. Patients with adhesive otitis media, unsuccessful grafts, revision and recurrent cases, radical mastoidectomy, and craniofacial anomalies were excluded...
November 11, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27630829/the-porx-response-regulator-of-the-porphyromonas-gingivalis-porxy-two-component-system-does-not-directly-regulate-the-type-ix-secretion-genes-but-binds-the-porl-subunit
#2
Maxence S Vincent, Eric Durand, Eric Cascales
The Type IX secretion system (T9SS) is a versatile multi-protein complex restricted to bacteria of the Bacteriodetes phylum and responsible for the secretion or cell surface exposition of diverse proteins that participate to S-layer formation, gliding motility or pathogenesis. The T9SS is poorly characterized but a number of proteins involved in the assembly of the secretion apparatus in the oral pathogen Porphyromonas gingivalis have been identified based on genome substractive analyses. Among these proteins, PorY, and PorX encode typical two-component system (TCS) sensor and CheY-like response regulator respectively...
2016: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/27509186/structural-insights-into-the-pork-and-porn-components-of-the-porphyromonas-gingivalis-type-ix-secretion-system
#3
Dhana G Gorasia, Paul D Veith, Eric G Hanssen, Michelle D Glew, Keiko Sato, Hideharu Yukitake, Koji Nakayama, Eric C Reynolds
The type IX secretion system (T9SS) has been recently discovered and is specific to Bacteroidetes species. Porphyromonas gingivalis, a keystone pathogen for periodontitis, utilizes the T9SS to transport many proteins including the gingipain virulence factors across the outer membrane and attach them to the cell surface via a sortase-like mechanism. At least 11 proteins have been identified as components of the T9SS including PorK, PorL, PorM, PorN and PorP, however the precise roles of most of these proteins have not been elucidated and the structural organization of these components is unknown...
August 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27220292/-analyses-of-the-operative-efficacy-of-102-cases-of-acquired-middle-ear-cholesteatoma
#4
Bo Yang, Xuejun Jiang, Ning Yang, Lian Hui, Buquan Wang, Yu Sun
OBJECTIVE: To investigate the efficacy of operations of acquired middle ear cholesteatoma. METHODS: Retrospectively analyzed clinical data of 102 patients whom received tympanoplasty with CWU or CWD with mastoid obliteration in our hospital between January 2014 and December 2014. Patients were divided into different groups according to types of the cholesteatoma as well as the different surgical procedures. Patients were followed up for 12-24 months, the pre and post-operative PTA was performed and evaluated...
May 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27118255/comparison-of-various-bone-cement-ossiculoplasty-techniques-and-functional-results
#5
Volkan Gungor, Gamze Atay, M Demir Bajin, Mehmet Yarali, Sarp Sarac, Levent Sennaroglu
OBJECTIVE: In this study, functional results of different bone cement ossiculoplasty techniques are compared. METHODS: Retrospective case review at a tertiary referral center. Patients who underwent middle ear surgery and bone cement ossiculoplasty between 2006-2012 were included. A total of 52 patients, including 30 patients with 'Incus to stapes' (Group 1) and 13 patients with 'malleus to stapes' (Group 2), five patients with 'incudoplasty + stapedotomy' (Group 3), and four patients with 'malleus to incus' (Group 4) ossiculoplasty were enrolled in the study...
September 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/26932959/long-term-outcomes-of-titanium-ossiculoplasty-in-chronic-otitis-media
#6
Brendan P O'Connell, Habib G Rizk, Tanisha Hutchinson, Shaun A Nguyen, Paul R Lambert
OBJECTIVE: The primary objective is to report long-term hearing outcomes (>2 years) after titanium ossiculoplasty in patients with chronic otitis media. STUDY DESIGN: Case series with chart review. SETTING: Tertiary care hospital. SUBJECTS AND METHODS: In total, 156 patients with chronic otitis media undergoing titanium ossiculoplasty were included. The primary outcome measure was the long-term postoperative ABG. The stability of hearing over time was determined by comparing short-term and long-term postoperative air-bone gap (ABG)...
June 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/26875721/-the-technique-of-hearing-reconstruction-in-the-cases-of-conductive-hearing-loss-with-malformed-tympanic-segment-of-facial-nerve
#7
Feng Yang, Rendong Song, Yang Liu
OBJECTIVE: To explore the technique of hearing reconstruction in the cases of conductive hearing loss with malformed tympanic segment of facial nerve. METHODS: Data of 10 cases from July 2010 to March 2015 were collected.The status of tympanic segment of facial nerve, malformed ossicles and the reconstructed methods of ossicular chain were analyzed and discussed based on the embryo anatomy and surgical technique. RESULTS: All facial nerves in 10 cases were exposed and drooping to stapes or cover the oval window...
February 2, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/26824916/cartilage-ossiculoplasty-in-cholesteatoma-surgery-hearing-results-and-prognostic-factors
#8
REVIEW
N Quaranta, S Taliente, F Coppola, I Salonna
Cartilage tympanoplasty is an established procedure for tympanic membrane and attic reconstruction. Cartilage has been used as an ossiculoplasty material for many years. The aim of this study was to evaluate hearing results of costal cartilage prostheses in ossicular chain reconstruction procedures in subjects operated on for middle ear cholesteatoma and to determine the presence of prognostic factors. Candidates for this study were patients affected by middle ear cholesteatoma whose ossicular chain was reconstructed with a chondroprosthesis...
October 2015: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/26716036/covering-the-staple-line-with-a-polyglycolic-acid-sheet-after-bullectomy-for-primary-spontaneous-pneumothorax-prevents-postoperative-recurrent-pneumothorax
#9
Kyoji Hirai, Tetsuo Kawashima, Shingo Takeuchi, Jitsuo Usuda
BACKGROUND: Postoperative recurrent pneumothorax (PORP) can arise after surgery for primary spontaneous pneumothorax (PSP) that is recurrent or involves prolonged air leakage. In this study, which included 265 patients (279 cases) with PSP who underwent surgery at our department, the percentage of patients that did not experience PORP was compared between a group that underwent bullectomy alone (group A) and a group in which the staple line and the surrounding visceral pleura were covered with a PGA sheet after bullectomy (group B) in order to study the utility of PGA sheets for preventing PORP...
November 2015: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/26595718/ossiculoplasty-with-titanium-prostheses-in-patients-with-intact-stapes-comparison-of-torp-versus-porp
#10
Andrew B Baker, Brendan P O'Connell, Shaun A Nguyen, Paul R Lambert
OBJECTIVES: Inferior rotation of the stapes or a small middle ear cleft can make placement of partial ossicular replacement prostheses (PORP) challenging. This study examines outcomes of total titanium prosthesis (TORP) ossiculoplasty in such patients and compares the results to PORPs. STUDY DESIGN: Review of prospective database. SETTING: Tertiary hospital. PATIENTS: Patients with an intact/mobile stapes undergoing titanium ossicular chain reconstruction from 2002 to 2014...
December 2015: Otology & Neurotology
https://www.readbyqxmd.com/read/26375972/does-checking-the-placement-of-ossicular-prostheses-via-the-posterior-tympanotomy-improve-hearing-results-after-cholesteatoma-surgery
#11
Allan Roux, David Bakhos, Alexandre Villeneuve, Ruben Hermann, Paul Suy, Emmanuel Lescanne, Eric Truy
INTRODUCTION: Posterior tympanotomy (PT) is often performed during the surgical management of middle ear cholesteatoma with extension in the retrotympanum area. This PT can also be used to control the right position of the ossicular prosthesis masked by the tympanic membrane reconstruction. OBJECTIVE: To compare audiologic results after ossiculoplasty performed via the outer ear canal and via the PT for patients with cholesteatoma. MATERIALS AND METHODS: Retrospective chart reviews were performed for 68 patients (68 ears) with cholesteatoma who underwent titanium ossicular prosthesis surgery between January 2007 and January 2011...
September 2015: Otology & Neurotology
https://www.readbyqxmd.com/read/26335290/hearing-outcome-after-sequential-cholesteatoma-surgery
#12
Susen Lailach, Thomas Zahnert, Nikoloz Lasurashvili, Max Kemper, Thomas Beleites, Marcus Neudert
The objective of this study was to assess hearing outcome after sequential cholesteatoma surgery stratified for exclusively transcanal technique (ETC), combined transcanal and transmastoidal technique (TCM) and canal wall down surgery (CWD) and to analyze the impact of ossicular reconstruction technique (partial ossicular replacement prostheses/PORP and total ossicular replacement prostheses/TORP) on hearing outcome. This study is a retrospective case review and clinical case study conducted in a tertiary referral center...
August 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/26259623/determinants-of-change-in-air-bone-gap-and-bone-conduction-in-patients-operated-on-for-chronic-otitis-media
#13
Maciej Wiatr, Agnieszka Wiatr, Jacek Składzień, Paweł Stręk
BACKGROUND: Middle ear surgery aims to eliminate pathology from the middle ear, improve drainage and ventilation of the postoperative cavity, and reconstruct the tympanic membrane and ossicles. The aim of this work is to define the factors that affect ABG (air-bone gap) and bone conduction in the patients operated on due to chronic otitis media. MATERIAL AND METHODS: A prospective analysis of patients operated on due to diseases of the middle ear during 2009-2012 was carried out...
2015: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/25193550/short-term-hearing-results-using-ossicular-replacement-prostheses-of-hydroxyapatite-versus-titanium
#14
Jong-Ik Lee, Shin-Hyuk Yoo, Chang Wook Lee, Chan Il Song, Myung Hoon Yoo, Hong Ju Park
The aim of this study was to compare the short-term audiologic results of the ossiculoplasty using partial or total ossicular replacement prostheses (PORP or TORP) made of hydroxyapatite (HA) and titanium (Ti). Fifty-two consecutive patients who underwent ossiculoplasty due to chronic otitis media with or without cholesteatoma were enrolled. Patients were assessed at 6 months postoperatively to establish short-term audiologic results. Preoperative and postoperative air-conduction and bone-conduction thresholds were measured at five frequencies: 0...
October 2015: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/25129971/-effect-of-ossicular-chain-reconstruction-with-titanium-ossicular-replacement-prosthesis-in-mastoidectomy-with-synchronous-ossiculoplasty
#15
COMPARATIVE STUDY
Min Mao, Jinming Zhai, Guangui Chen, Jianguo Zhang, Zhaoen Ma, Jinping Xue
OBJECTIVE: To assess hearing effect of ossicular chain reconstruction with titanium ossicular replacement prosthesis during mastoidectomy with synchronous ossiculoplasty in chronic middle ear disease. METHOD: Retrospective reviews were performed for 139 patients who had underwent mastoidectomy and tympanoplasty with titanium ossicular replacement prostheses at the same time between 2008 and 2011. The partial ossicular replacement prostheses (PORP) were used in 91 patients and the total ossicular replacement prostheses (TORP) were used in 48 patients respectively...
May 2014: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/25009804/ossiculoplasty-a-prospective-study-of-80-cases
#16
Shrinivas Shripatrao Chavan, Prateek V Jain, Jeevan N Vedi, Dharmendra Kumar Rai, Himayat Kadri
INTRODUCTION: The use of ossicular graft material in ossicular chain reconstruction has significantly improved hearing results hearing after tympanoplasty and tympanomastoid surgery for chronic otitis media. Today, otologists have a wide array of tools from which to choose, but may find it difficult to know which middle ear implant works best. MATERIALS AND METHODS: A prospective study of 80 patients who underwent ossiculoplasty was performed in the ear, nose, and throat (ENT) department at a tertiary health care facility from 2011 to 2013...
July 2014: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/24974404/-lysis-of-the-incus-long-process-and-incudostapedial-rebridging-ossiculoplasty-comparative-study-of-titanium-gold-angle-prosthesis-plester-type-versus-martin-incudo-prosthesis-hydroxylapatite
#17
COMPARATIVE STUDY
M B Faye, C Martin, S Schmerber
OBJECTIVES: We report two surgical techniques devised to restore a disrupted incudostapedial joint. MATERIAL AND METHODS: Thirty patients underwent rebridging of distal portion of incus long process in the ENT Department of University of Grenoble and Saint-Etienne, between October 1998 and September 2002. Two types of ossicular prostheses were used: A titanium-gold angle prosthesis according to Plester Winkel Kurz (n = 16 patients), and a hydroxylapatite prosthesis as Martin Incudo Prosthesis (n = 14 patients)...
2013: Revue de Laryngologie—Otologie—Rhinologie
https://www.readbyqxmd.com/read/24954899/canal-wall-up-tympanoplasty-for-cholesteatoma-with-intact-stapes-comparison-of-hearing-results-between-cartilage-and-porp-on-stapes-and-impact-of-malleus-removal-and-total-reinforcement-of-the-tympanic-membrane-by-cartilage
#18
COMPARATIVE STUDY
C Quérat, C Martin, J-M Prades, C Richard
OBJECTIVES: To compare the results obtained with canal wall up (CWU) tympanoplasty for cholesteatoma using cartilage or an hydroxyapatite (HA) PORP positioned on the head of the stapes and to analyse the impact of malleus removal and total reinforcement of the tympanic membrane with cartilage. MATERIALS AND METHODS: Retrospective study of 128 cases (99 adults, 29 children) operated between 2003 and 2012 for cholesteatoma by CWU tympanoplasty with use of a cartilage graft (90 cases) or a PORP (38 cases) on the head of the stapes...
September 2014: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/24935173/usefulness-of-a-ventilation-tube-as-a-partial-ossicular-replacement-prosthesis-porp-in-ossiculoplasty-in-patients-with-chronic-otitis-media
#19
Maciej Wiatr, Jacek Składzień, Jerzy Tomik, Paweł Stręk
BACKGROUND: The principal objective of ossiculoplasty is to reconstruct the sound-conducting system in the ear to the best possible degree after the elimination of pathological lesions from the middle ear. The ossicular chain is reconstructed with the use of the patient's own properly modelled ossicles and synthetic prostheses. The objective of the study was to assess the degree of hearing improvement after tympanoplasty in patients for whom a ventilation tube was used as a partial ossicular replacement prosthesis (PORP)...
June 13, 2014: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/24924117/comparison-of-early-hearing-outcomes-of-type-2-ossiculoplasty-using-hydroxyapatite-bone-cement-versus-other-materials
#20
COMPARATIVE STUDY
C Galy-Bernadoy, M Akkari, C Mathiolon, M Mondain, A Uziel, F Venail
OBJECTIVES: To compare the hearing outcomes of type 2 ossiculoplasties for erosion of the long process of the incus according to the reconstruction material used: cartilage, ossicles, hydroxyapatite (HAP) partial ossiculoplasty reconstruction prostheses (PORP), titanium PORP, and HAP cement. Complications related to cement reconstruction were systematically investigated and reported. MATERIAL AND METHODS: Seventy patients operated between 2007 and 2011 for non-cholesteatomatous chronic otitis media were included in this study...
November 2014: European Annals of Otorhinolaryngology, Head and Neck Diseases
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