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https://www.readbyqxmd.com/read/28623549/elevated-circulating-pcsk9-concentrations-predict-subclinical-atherosclerotic-changes-in-low-risk-obese-and-non-obese-patients
#1
Štefan Tóth, Ján Fedačko, Tímea Pekárová, Zdenka Hertelyová, Matan Katz, Adil Mughees, Jozef Kuzma, Peter Štefanič, Ivan Kopolovets, Daniel Pella
INTRODUCTION: Many studies have highlighted the important role of PCSK9 in the development of cardiometabolic changes and its possible function as a biomarker of myocardial infarction or ischemic heart disease. This study aimed to determine the relationship between circulating PCSK9 levels and subclinical vascular changes in the group of low risk patients without manifest cardiovascular diseases. METHODS: In this study, 120 healthy patients, free of manifest cardiovascular diseases, diabetes mellitus, and without lipid-lowering therapy, were divided into three groups based on BMI: normal weight (N = 50), overweight (N = 30), and obese (N = 40)...
June 16, 2017: Cardiology and Therapy
https://www.readbyqxmd.com/read/28617732/the-effects-of-latanoprost-with-benzalkonium-chloride-versus-travoprost-with-sofzia-on-the-ocular-surface
#2
Kamran Rahmatnejad, Christopher J Rapuano, Parul Ichhpujani, Sheryl S Wizov, Marlene R Moster, Lisa A Hark, L Jay Katz
PURPOSE: To assess ocular surface changes in participants using latanoprost with benzalkonium chloride (Xalatan) and travoprost with SofZia (Travatan Z). METHODS: In this prospective, open-label, nonrandomized cohort study, participants were classified into two groups: group 1 (n=28) naive to glaucoma therapy, group 2 (n=27) on previous Xalatan monotherapy in both eyes. Both groups started (or continued) Xalatan in the right eye and Travatan Z in the left eye. Baseline, 1-, and 2-month measurements of tear breakup time (TBUT), corneal staining score, conjunctival staining score, conjunctival hyperemia score, tear production, and intraocular pressure were obtained...
June 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28614524/family-vulnerability-index-to-disability-and-dependence-fvi-dd-by-social-and-health-conditions
#3
Fernanda Amendola, Márcia Regina Martins Alvarenga, Maria do Rosário Dias de Oliveira Latorre, Maria Amélia de Campos Oliveira
The Family Vulnerability Index to Disability and Dependence (FVI-DD) aims to summarize the dimensions of vulnerability to disability and dependence using family data monitored by Family Health Strategy (ESF) teams. This study aims to analyze the FVI-DD according to the social and health vulnerability, to validate and extract a cutoff point for each dimension. The FVI-DD was built with a sample of 248 families living in a region of São Paulo. The dimension related to health conditions was validated with good internal consistency, with respect to the Katz Index and the Lawton Scale, whereas the dimension related to social conditions was only validated in relation to Lawton Scale...
June 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28591386/impact-of-insomnia-on-self-perceived-health-in-the-elderly
#4
Janiciene Silva, Annibal Truzzi, Fayanne Schaustz, Roberta Barros, Marisa Santos, Jerson Laks
Objective: To investigate the association between self-perceived health, and sociodemographic and clinical factors in a sample of elderly outpatients in Rio de Janeiro. Methods: A sample of 345 elderly patients was assessed with an anamnesis, Lawton and Brody's Scale, Katz Index, Geriatric Depression Scale, Timed Up and Go Test, and Study of Osteoporotic Fracture Index. Logistic regression analyses were performed to investigate the predictors of self-perceived health...
May 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28573369/systolic-and-pulse-pressure-associate-with-incident-knee-osteoarthritis-data-from-the-osteoarthritis-initiative
#5
Grace H Lo, Timothy E McAlindon, Jeffrey N Katz, Jeffrey B Driban, Lori Lyn Price, Charles B Eaton, Nancy J Petersen, Christie M Ballantyne, Maria E Suarez-Almazor
We evaluated the relationship of systolic blood pressure, diastolic blood pressure, pulse pressure, and treatment with antihypertensives with knee osteoarthritis incidence in a US cohort. We performed a longitudinal study (2004-2010) nested within the Osteoarthritis Initiative Study including only individuals without knee osteoarthritis at baseline. Systolic blood pressure, diastolic blood pressure, and pulse pressure were assessed at baseline, 12-, 24-, and 36-month visits. Knee radiographs at baseline, 12-, 24-, 36- and 48-month visits defined radiographic osteoarthritis, Kellgren and Lawrence grade ≥2...
June 1, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28532777/predictive-value-of-age-adjusted-charlson-co-morbidity-index-for-1-3-and-5-year-mortality-in-patients-requiring-transcatheter-mitral-valve-repair
#6
Mike Saji, Marc R Katz, Gorav Ailawadi, Dale E Fowler, Michael Ragosta, D Scott Lim
Co-morbidities increase markedly with aging, and they often negatively affect its prognosis. Although mortality with transcatheter mitral valve repair (TMVr) is significantly less than for open mitral valve surgery in patients at high surgical risk, it remains a concern to identify which patients will benefit from this treatment. Some prognostic metrics have been reported to guide better patient selection; however, universal risk stratification measures have not been established. This study aimed to determine if age-adjusted Charlson co-morbidity index (CCI) could predict mortality in patients who underwent TMVr and to assess its discriminatory performance in long-term outcomes...
July 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28527731/the-effect-of-activities-of-daily-living-on-the-self-care-agency-of-patients-in-a-cardiovascular-surgery-clinic
#7
Papatya Karakurt, Necla Kasimoğlu, Aybike Bahçeli, Sebahat Atalikoğlu Başkan, Burcu Ağdemir
Cardiovascular diseases are the leading cause of death globally, and nurses have a crucial role in informing cardiovascular disease patients about their diseases. The aim of the present study was to identify the effect of activities of daily living on the self-care agency of patients in a cardiovascular surgery clinic. This descriptive study was conducted between June 2014 and January 2015 with 180 patients hospitalized in the cardiovascular surgery clinic of a university hospital in the province of Erzincan in the Eastern region of Turkey...
June 2017: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/28525354/the-relationship-between-insulin-resistance-and-endothelial-dysfunction-in-obese-adolescents
#8
Preneet Cheema Brar, Payal Patel, Stuart Katz
BACKGROUND: Insulin resistance and endothelial dysfunction share a reciprocal relationship that links the metabolic and cardiovascular sequelae of obesity. We characterized the brachial artery reactivity testing (BART) and carotid artery-intima media thickness (CIMT) in adolescents categorized as obese insulin resistant (OIR) and obese not insulin resistant (ONIR). Lipoprotein particle (p) analysis and inflammatory cytokines in OIR and ONIR groups were also analyzed. METHODS: Obese adolescents (n=40; mean body mass index [BMI] 35...
May 24, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28522656/comparison-between-different-measures-of-body-fat-with-kidney-function-decline-and-incident-ckd
#9
Magdalena Madero, Ronit Katz, Rachel Murphy, Anne Newman, Kushang Patel, Joachim Ix, Carmen Peralta, Suzanne Satterfield, Linda Fried, Michael Shlipak, Mark Sarnak
BACKGROUND AND OBJECTIVES: Although anthropometric measures of body fat are associated with development of CKD, they may not be able to distinguish between various forms of fat and therefore may be less accurate than computed tomography (CT) measures. We compared the association of CT and anthropometric measures of obesity with kidney outcomes in the Health Aging and Body Composition Study. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Participants were recruited from March of 1997 through July of 1998...
June 7, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28509820/impact-of-preoperative-opioid-use-on-total-knee-arthroplasty-outcomes
#10
Savannah R Smith, Jennifer Bido, Jamie E Collins, Heidi Yang, Jeffrey N Katz, Elena Losina
BACKGROUND: There is growing concern about the use of opioids prior to total knee arthroplasty (TKA), and research has suggested that preoperative opioid use may lead to worse pain outcomes following surgery. We evaluated the pain relief achieved by TKA in patients who had and those who had not used opioids use before the procedure. METHODS: We augmented data from a prospective cohort study of TKA outcomes with opioid-use data abstracted from medical records. We collected patient-reported outcomes and demographic data before and 6 months after TKA...
May 17, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28492771/functional-disability-indicators-and-associated-factors-in-the-elderly-a-population-based-study-in-bag%C3%A3-rio-grande-do-sul-brazil
#11
Juliana Damasceno Nunes, Mirelle de Oliveira Saes, Bruno Pereira Nunes, Fernando Carlos Vinholes Siqueira, Deisi Cardoso Soares, Maria Elizabeth Gastal Fassa, Elaine Thumé, Luiz Augusto Facchini
OBJECTIVE: to estimate the prevalence of functional disability in basic and instrumental daily activities and associated factors in elderly who live in the urban area of Bagé-RS, Brazil. METHODS: this is a population-based cross-sectional study, conducted in 2008; functional disability was defined by basic and instrumental daily activities, using Katz index and Lawton and Brody scale; Poisson regression was used for crude and adjusted analyses. RESULTS: 1,593 elderly individuals were investigated; the prevalence of disability for basic activities was of 10...
April 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28471534/predicting-suicide-with-the-sad-persons-scale
#12
Cara Katz, Jason R Randall, Jitender Sareen, Dan Chateau, Randy Walld, William D Leslie, JianLi Wang, James M Bolton
BACKGROUND: Suicide is a major public health issue, and a priority requirement is accurately identifying high-risk individuals. The SAD PERSONS suicide risk assessment scale is widely implemented in clinical settings despite limited supporting evidence. This article aims to determine the ability of the SAD PERSONS scale (SPS) to predict future suicide in the emergency department. METHODS: Five thousand four hundred sixty-two consecutive adults were seen by psychiatry consultation teams in two tertiary emergency departments with linkage to population-based administrative data to determine suicide deaths within 6 months, 1, and 5 years...
May 4, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28451770/multi-modality-imaging-of-the-leaking-ureter-why-does-detection-of-traumatic-and-iatrogenic-ureteral-injuries-remain-a-challenge
#13
Abdullah Alabousi, Michael N Patlas, Christine O Menias, David Dreizin, Sanjeev Bhalla, Man Hon, Andres O'Brien, Douglas S Katz
Ureteral injuries are uncommon in trauma patients, accounting for fewer than 1% of all injuries to the urinary tract. These uncommon, yet problematic, injuries can often be overlooked in the standard search pattern on abdominal and pelvic multi-detector CT (MDCT) images, as radiologists focus on more immediate life-threatening injuries. However, early diagnosis and management are vital to reduce potential morbidity. If there is a high clinical index of suspicion for ureteral injuries with penetrating or blunt trauma, or if there is suspected iatrogenic ureteral injury, delayed-phase/urographic-phase MDCT images are essential for confirming the diagnosis...
April 27, 2017: Emergency Radiology
https://www.readbyqxmd.com/read/28444299/environmental-factors-associated-with-disease-flare-in-juvenile-and-adult-dermatomyositis
#14
Gulnara Mamyrova, Lisa G Rider, Alison Ehrlich, Olcay Jones, Lauren M Pachman, Robert Nickeson, Lisa G Criscone-Schreiber, Lawrence K Jung, Frederick W Miller, James D Katz
Objective.: The aim was to assess environmental factors associated with disease flare in juvenile and adult dermatomyositis (DM). Methods.: An online survey of DM patients from the USA and Canada examined smoking, sun exposure, infections, medications, vaccines, stressful life events and physical activity during the 6 months before flares, or in the past 6 months in patients without flares. Differences were evaluated by χ 2 and Fisher's exact tests, and significant univariable results were examined in multivariable logistic regression...
April 21, 2017: Rheumatology
https://www.readbyqxmd.com/read/28414806/cost-effectiveness-of-nurse-led-multifactorial-care-to-prevent-or-postpone-new-disabilities-in-community-living-older-people-results-of-a-cluster-randomized-trial
#15
RANDOMIZED CONTROLLED TRIAL
Jacqueline J Suijker, Janet L MacNeil-Vroomen, Marjon van Rijn, Bianca M Buurman, Sophia E de Rooij, Eric P Moll van Charante, Judith E Bosmans
OBJECTIVE: To evaluate the cost-effectiveness of nurse-led multifactorial care to prevent or postpone new disabilities in community-living older people in comparison with usual care. METHODS: We conducted cost-effectiveness and cost-utility analyses alongside a cluster randomized trial with one-year follow-up. Participants were aged ≥ 70 years and at increased risk of functional decline. Participants in the intervention group (n = 1209) received a comprehensive geriatric assessment and individually tailored multifactorial interventions coordinated by a community-care registered nurse with multiple follow-up visits...
2017: PloS One
https://www.readbyqxmd.com/read/28414066/factors-associated-with-maintenance-of-body-mass-index-in-the-jackson-heart-study-a-prospective-cohort-study-secondary-analysis
#16
Brandon J Auerbach, Ronit Katz, Katherine Tucker, Edward J Boyko, Adam Drewnowski, Alain Bertoni, Patricia Dubbert, DeMarc A Hickson, Adolfo Correa, Bessie A Young
The purpose of this study was to compare the relationship of diet quality, physical activity, and environmental factors with body mass index (BMI) maintenance in African American adults. We analyzed data from 4041 participants in the Jackson Heart Study, a prospective cohort study based in Jackson, Mississippi. Exposures were baseline American Heart Association diet quality score, American Heart Association physical activity categories, the built environment, the food environment, and neighborhood safety. The outcome was weight maintenance or loss (no BMI increase ≥1...
July 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28398076/refining-low-physical-activity-measurement-improves-frailty-assessment-in-advanced-lung-disease-and-survivors-of-critical-illness
#17
Matthew R Baldwin, Jonathan P Singer, Debbie Huang, Jessica Sell, Wendy C Gonzalez, Lauren Pollack, Mathew S Maurer, Frank F D'Ovidio, Matthew Bacchetta, Joshua R Sonett, Selim M Arcasoy, Lori Shah, Hilary Robbins, Steven R Hays, Jasleen Kukreja, John R Greenland, Rupal J Shah, Lorriana Leard, Matthew Morrell, Cynthia Gries, Patricia P Katz, Jason D Christie, Joshua M Diamond, David J Lederer
RATIONALE: The frail phenotype has gained popularity as a clinically relevant measure in adults with advanced lung disease and critical illness survivors. Since respiratory disease and chronic illness can greatly limit physical activity, the measurement of participation in traditional leisure-time activities as a frailty component may lead to substantial misclassification of frailty in pulmonary and critical care patients. OBJECTIVES: To test and validate replacing the Duke Activities Scale Index (DASI), a simple 12-item questionnaire, for the Minnesota Leisure Time Activities (MLTA), a detailed questionnaire covering 18 leisure time activities, as the measure of low activity in the Fried frailty phenotype instrument (FFP)...
April 11, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28393498/the-impact-of-obesity-and-adiposity-on-inflammatory-markers-in-patients-with-rheumatoid-arthritis
#18
Michael D George, Jon T Giles, Patricia P Katz, Bryant R England, Ted R Mikuls, Kaleb Michaud, Alexis R Ogdie-Beatty, Said Ibrahim, Grant W Cannon, Liron Caplan, Brian C Sauer, Joshua F Baker
BACKGROUND: C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are important disease activity biomarkers in rheumatoid arthritis (RA). This study aimed to determine to what extent obesity biases these biomarkers. METHODS: Body mass index (BMI) associations with CRP and ESR were assessed in two RA cohorts - 1) the cross-sectional Body Composition (BC) cohort (N = 451) including whole-body DXA measures of fat mass index, and 2) the longitudinal Veterans Affairs Rheumatoid Arthritis (VARA) registry (N = 1652), using multivariable models stratified by sex...
April 10, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28382734/maternal-super-obesity-and-risk-for-intensive-care-unit-admission-in-the-mfmu-cesarean-registry
#19
Marcela C Smid, Sarah K Dotters-Katz, Arthur J Vaught, Catherine J Vladutiu, Kim A Boggess, David M Stamilio
INTRODUCTION: Obesity is a risk factor for intensive care unit (ICU) admission in nonpregnant populations. Less is known about maternal obesity and ICU admission risk. The objective of this study was to estimate the association between maternal obesity and ICU admission among women who delivered via cesarean section or vaginal birth after cesarean section (VBAC). MATERIAL AND METHODS: This is a retrospective cohort analysis of women who delivered via VBAC or cesarean section in the Maternal-Fetal Medicine Unit (MFMU) Cesarean Registry...
April 6, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28379824/fitwits-tm-leads-to-improved-parental-recognition-of-childhood-obesity-and-plans-to-encourage-change
#20
Bethany A Edwards, Jonathan R Powell, Ann McGaffey, Valerie M P Wislo, Elaine Boron, Frank J D'Amico, Linda Hogan, Kristin Hughes, Ilene Katz Jewell, Diane J Abatemarco
INTRODUCTION: Brief tools are needed to help physicians and parents reach consensus on body mass index (BMI) categories for children and to discuss health-improving behaviors. This study tested the Fitwits(TM) intervention with interactive flashcards and before and- after surveys to improve parents' perceptions of children's BMI status. METHODS: We enrolled 140 parents and their 9- to 12-year-old children presenting for well child care, regardless of BMI status, scheduled with 53 Fitwits-trained physicians...
March 2017: Journal of the American Board of Family Medicine: JABFM
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