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https://www.readbyqxmd.com/read/29793191/development-and-validation-of-a-prediction-model-for-functional-decline-in-older-medical-inpatients
#1
Toshihiko Takada, Shingo Fukuma, Yosuke Yamamoto, Yukio Tsugihashi, Hiroyuki Nagano, Michio Hayashi, Jun Miyashita, Teruhisa Azuma, Shunichi Fukuhara
OBJECTIVE: To prevent functional decline in older inpatients, identification of high-risk patients is crucial. The aim of this study was to develop and validate a prediction model to assess the risk of functional decline in older medical inpatients. METHODS: In this retrospective cohort study, patients ≥65 years admitted acutely to medical wards were included. The healthcare database of 246 acute care hospitals (n = 229,913) was used for derivation, and two acute care hospitals (n = 1767 and 5443, respectively) were used for validation...
May 17, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29781357/cognitive-and-physical-function-of-people-older-than-80-years-in-china-from-1998-to-2014
#2
Xiaoqian Hu, Yuhang Zeng, Xuemei Zhen, Hao Zhang, Yuanyuan Li, Shuyan Gu, Hengjin Dong
Objectives This study was performed to describe the health status of Chinese oldest-old individuals aged ≥80 years from 1998 to 2014 and explore differences in their health status based on demographic characteristics and socioeconomic status. Methods Data were obtained from the seven waves of the Chinese Longitudinal Healthy Longevity Survey. The Mini Mental State Examination, Katz Index of Independence in Activities of Daily Living, and chair stand test were used to examine cognitive and physical function...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29772994/improvement-in-sleep-quality-after-carpal-tunnel-release
#3
Arie G Trouw, Ashish Patel, Andrew Yang, Julio Jauregui, Daniel Caligiuri, Jack Choueka
Carpal tunnel syndrome (CTS) has multiple implications on patient quality of life. In particular, CTS may affect quality of sleep, causing sleep deprivation in extreme cases. Carpal tunnel release (CTR) surgery may aid in resolving these disturbances. The purpose of our study was to investigate whether patients who have undergone CTR have improved sleep quality and to determine the timeline for such improvement. Twenty-one patients were prospectively enrolled and followed-up for two years. They were asked to complete a Pittsburgh Sleep Quality Index (PSQI), a pain visual analog scale (VAS), a sleep perception VAS, and both components Symptom Severity and Functional Status Scale from the Levine-Katz carpal tunnel questionnaire...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29744856/risk-factors-associated-with-gastroenteropancreatic-neuroendocrine-tumors-gep-net-in-a-cohort-of-2-3-million-israeli-adolescents
#4
L H Katz, Z Levi, G Twig, J D Kark, A Leiba, E Derazne, I Liphshiz, L K Boker, S Eisenstein, A Afek
We investigated whether obesity and socio-demographic factors at adolescence are associated with incident gastroenteropancreatic neuroendocrine tumors (GEP-NET).Our cohort included 2.3 million Israeli adolescents examined at ages 16 to 19 years between 1967 and 2010. The baseline database included sex, country of birth, residential socio-economic status (SES), body-mass index (BMI) and height. Participants were followed through linkage with the National Cancer Registry up to 2012. We identified 221 cases of GEP-NET (66 pancreatic, 52 gastric, 39 rectal, 27 appendiceal, 23 small bowel and 14 colonic)...
May 9, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29744645/reasons-for-delaying-surgery-following-hip-fractures-and-its-impact-on-one-year-mortality
#5
Alejandro Lizaur-Utrilla, Blanca Gonzalez-Navarro, Maria F Vizcaya-Moreno, Francisco A Miralles Muñoz, Santiago Gonzalez-Parreño, Fernando A Lopez-Prats
PURPOSE: The purposes of this study were to identify the reasons for delayed surgery following hip fractures and analyze the impact of these reasons on 1-year mortality. METHODS: A prospective cohort study of 1234 patients with mean age of 83.1 (range 65-92, SD 8.0) who underwent hip fracture surgery compared three subgroups: (1) surgery within two days from admission (609 patients); (2) delayed surgery for medical reasons (286); and (3) delayed surgery for organizational causes (339)...
May 9, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29740985/obesity-independently-associates-with-worse-patient-reported-outcomes-in-women-with-systemic-lupus-erythematosus
#6
Sarah L Patterson, Gabriela Schmajuk, Kashif Jafri, Jinoos Yazdany, Patricia Katz
BACKGROUND: We aimed to determine whether obesity in women with systemic lupus erythematosus (SLE) independently associates with worse patient-reported outcomes (PROs). METHODS: Data derive from a prospective study of adult women who carried a diagnosis of SLE verified by medical record review. Two established definitions for obesity were used: fat mass index (FMI) ≥ 13 kg/m2 and BMI ≥ 30 kg/m2 . Dependent variables included 4 validated PROs: disease activity via Systemic Lupus Activity Questionnaire (SLAQ), depressive symptoms via Center for Epidemiologic Studies Depression Scale (CES-D), pain via Short Form 36 Health Survey (SF-36) Pain Subscale, and fatigue via SF-36 Vitality Subscale...
May 8, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29686276/management-options-for-patients-with-gerd-and-persistent-symptoms-on-proton-pump-inhibitors-recommendations-from-an-expert-panel
#7
Rena Yadlapati, Michael F Vaezi, Marcelo F Vela, Stuart J Spechler, Nicholas J Shaheen, Joel Richter, Brian E Lacy, David Katzka, Philip O Katz, Peter J Kahrilas, C Prakash Gyawali, Lauren Gerson, Ronnie Fass, Donald O Castell, Jenna Craft, Luke Hillman, John E Pandolfino
BACKGROUND: The aim of this study was to assess expert gastroenterologists' opinion on treatment for distinct gastroesophageal reflux disease (GERD) profiles characterized by proton pump inhibitor (PPI) unresponsive symptoms. METHODS: Fourteen esophagologists applied the RAND/UCLA Appropriateness Method to hypothetical scenarios with previously demonstrated GERD (positive pH-metry or endoscopy) and persistent symptoms despite double-dose PPI therapy undergoing pH-impedance monitoring on therapy...
April 24, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29664853/effects-of-a-single-intra-articular-injection-of-a-microsphere-formulation-of-triamcinolone-acetonide-on-knee-osteoarthritis-pain-a-double-blinded-randomized-placebo-controlled-multinational-study
#8
Philip G Conaghan, David J Hunter, Stanley B Cohen, Virginia B Kraus, Francis Berenbaum, Jay R Lieberman, Deryk G Jones, Andrew I Spitzer, David S Jevsevar, Nathaniel P Katz, Diane J Burgess, Joelle Lufkin, James R Johnson, Neil Bodick
BACKGROUND: Intra-articular corticosteroids relieve osteoarthritis pain, but rapid systemic absorption limits efficacy. FX006, a novel, microsphere-based, extended-release triamcinolone acetonide (TA) formulation, prolongs TA joint residence and reduces systemic exposure compared with standard TA crystalline suspension (TAcs). We assessed symptomatic benefits and safety of FX006 compared with saline-solution placebo and TAcs. METHODS: In this Phase-3, multicenter, double-blinded, 24-week study, adults ≥40 years of age with knee osteoarthritis (Kellgren-Lawrence grade 2 or 3) and average-daily-pain (ADP)-intensity scores of ≥5 and ≤9 (0 to 10 numeric rating scale) were centrally randomized (1:1:1) to a single intra-articular injection of FX006 (32 mg), saline-solution placebo, or TAcs (40 mg)...
April 18, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29642875/comparing-the-performance-of-circulating-cathodic-antigen-and-kato-katz-techniques-in-evaluating-schistosoma-mansoni-infection-in-areas-with-low-prevalence-in-selected-counties-of-kenya-a-cross-sectional-study
#9
Collins Okoyo, Elses Simiyu, Sammy M Njenga, Charles Mwandawiro
BACKGROUND: Kato-Katz technique has been the mainstay test in Schistosoma mansoni diagnosis in endemic areas. However, recent studies have documented its poor sensitivity in evaluating Schistosoma mansoni infection especially in areas with lower rates of transmission. It's the primary diagnostic tool in monitoring impact of the Kenya national school based deworming program on infection transmission, but there is need to consider a more sensitive technique as the prevalence reduces. Therefore, this study explored the relationship between results of the stool-based Kato-Katz technique with urine-based point-of-care circulating cathodic antigen (POC-CCA) test in view to inform decision-making by the program in changing from Kato-Katz to POC-CCA test...
April 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29581209/index-coronary-angiography-use-in-manitoba-canada-a-population-level-descriptive-analysis-of-first-nations-and-non-first-nations-recipients
#10
Annette S H Schultz, Lindsey Dahl, Elizabeth McGibbon, R Jarvis Brownlie, Catherine Cook, Basem Elbarouni, Alan Katz, Thang Nguyen, Jo Ann Sawatzky, Moneca Sinclaire, Karen Throndson, Randy Fransoo
OBJECTIVES: To investigate recipient characteristics and rates of index angiography among First Nations (FN) and non-FN populations in Manitoba, Canada. SETTING: Population-based, secondary analysis of provincial administrative health data. PARTICIPANTS: All adults 18 years or older who received an index angiogram between 2000/2001 and 2008/2009. PRIMARY AND SECONDARY OUTCOME MEASURES: (1) Descriptive statistics for age, sex, income quintile by rural and urban residency and Charlson Comorbidity Index for FN and non-FN recipients...
March 25, 2018: BMJ Open
https://www.readbyqxmd.com/read/29580279/distinct-clinical-characteristics-and-helminth-co-infections-in-adult-tuberculosis-patients-from-urban-compared-to-rural-tanzania
#11
George Sikalengo, Jerry Hella, Francis Mhimbira, Liliana K Rutaihwa, Farida Bani, Robert Ndege, Mohamed Sasamalo, Lujeko Kamwela, Khadija Said, Grace Mhalu, Yeromin Mlacha, Christoph Hatz, Stefanie Knopp, Sébastien Gagneux, Klaus Reither, Jürg Utzinger, Marcel Tanner, Emilio Letang, Maja Weisser, Lukas Fenner
BACKGROUND: Differences in rural and urban settings could account for distinct characteristics in the epidemiology of tuberculosis (TB). We comparatively studied epidemiological features of TB and helminth co-infections in adult patients from rural and urban settings of Tanzania. METHODS: Adult patients (≥ 18 years) with microbiologically confirmed pulmonary TB were consecutively enrolled into two cohorts in Dar es Salaam, with ~ 4.4 million inhabitants (urban), and Ifakara in the sparsely populated Kilombero District with ~ 400 000 inhabitants (rural)...
March 24, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29575023/progression-and-new-onset-of-nonalcoholic-fatty-liver-disease-in-living-kidney-donors-compared-to-healthy-controls
#12
Helena Katchman, Shira Zelber-Sagi, Roni Baruch, Galia Berman, Idit F Schwartz, Doron Schwartz, Richard Nakache, Yaacov Goykhman, Polina Katz, Oren Shibolet, Moshe Shashar, Ayelet Grupper
BACKGROUND: There is growing evidence linking nonalcoholic fatty liver disease (NAFLD) with reduced glomerular filtration rate (GFR). Living kidney donors do not have underlying kidney disease, but have reduced GFR as a result of nephrectomy. Whether kidney donation is associated with a higher risk for development or progression of NAFLD is currently unknown. METHODS: Retrospective evaluation of metabolic parameters and sonographic evidence of NAFLD were performed in 232 living kidney donors and 162 healthy controls...
March 25, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29557871/a-conceptual-model-for-the-evaluation-of-surgical-missions
#13
Jennifer Bido, Roya Ghazinouri, Jamie E Collins, Desirée Diez Portela, Luis Alcantara, Thomas S Thornhill, Jeffrey N Katz
BACKGROUND: Medical missions to low and middle-income countries are increasingly frequent, with an estimated 6,000 trips sponsored by U.S. organizations accounting for approximately 200,000 surgical cases and $250 million in costs annually. However, these missions have received little critical evaluation. This paper describes the research program Operation Walk (Op-Walk) Boston, and proposes an evaluation model for similar surgical missions. METHODS: We propose an evaluation model, borrowing from the work of Donabedian and enriched by evidence from our research program...
March 21, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29550201/effect-of-malnutrition-on-radical-nephroureterectomy-morbidity-and-mortality-opportunity-for-preoperative-optimization
#14
Matthew Katz, Daniel A Wollin, Nicholas M Donin, William Meeks, Scott Gulig, Lee C Zhao, James S Wysock, Samir S Taneja, William C Huang, Marc A Bjurlin
INTRODUCTION: Nutritional status has been increasingly recognized as an important predictor of prognosis and surgical outcomes for cancer patients. We evaluated the effect of preoperative malnutrition on the development of surgical complications and mortality after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). MATERIALS AND METHODS: Using data from the American College of Surgeons National Surgical Quality Improvement Program, we evaluated the association of poor nutritional status with 30-day postoperative complications and overall mortality after RNU from 2005 to 2015...
February 23, 2018: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29526480/evaluating-a-point-of-care-circulating-cathodic-antigen-test-poc-cca-to-detect-schistosoma-mansoni-infections-in-a-low-endemic-area-in-north-eastern-brazil
#15
Fernando Schemelzer Moraes Bezerra, Joames Kauffimann Freitas Leal, Mariana Silva Sousa, Marta Cristhiany Cunha Pinheiro, Alberto Novaes Ramos, Vanessa Silva-Moraes, Naftale Katz
Schistosomiasis is still a public health problem in Brazil. The Kato-Katz test is the most frequently used diagnostic method for Schistosoma mansoni infection. However, it lacks sensitivity in areas of low prevalence. We have assessed the positivity rate of S. mansoni infection in Bananeiras, a village on Capistrano, Ceara, Brazil by performing a point-of-care test in urine to determine the circulating cathodic antigens (POC-CCA), and we compared the findings with those of the Kato-Katz technique for egg detection in stool and an enzyme-linked immunosorbent assay for specific antibodies against adult worms (SWAP-ELISA) in serum before treatment (baseline)...
June 2018: Acta Tropica
https://www.readbyqxmd.com/read/29477678/prognostic-factors-for-arteriovenous-fistula-maturation
#16
Carney Chan, Christian J Ochoa, Steven G Katz
BACKGROUND: Recent studies have reported successful arteriovenous (AV) fistula maturation rates between 40% and 80%, with older age, distal fistula location, and small vein diameter associated with greater failure rates. Our objective is to determine if these findings are consistent with the outcomes at our institution. METHODS: A retrospective chart review was performed on patients who underwent upper extremity AV fistula creation at a single institution. Patient demographics and risk factors were analyzed, as well as fistula location and vein diameter based on preoperative ultrasound...
May 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29475795/race-and-stroke-in-an-atrial-fibrillation-inception-cohort-findings-from-the-penn-atrial-fibrillation-free-study
#17
Parin J Patel, Ronit Katz, Yuliya Borovskiy, Anthony Killian, Joshua M Levine, Nelson W McNaughton, David Callans, Gregory Supple, Sanjay Dixit, Andrew E Epstein, Francis E Marchlinski, Rajat Deo
BACKGROUND: Stroke may be the initial manifestation of atrial fibrillation (AF). Limited studies, however, have evaluated racial differences in stroke before the diagnosis of AF. OBJECTIVE: We assessed racial differences in strokes that occurred before and after AF diagnosis in the Penn Atrial Fibrillation Free study. METHODS: The Penn Atrial Fibrillation Free study consists of 56,835 patients from the University of Pennsylvania Health System who were free of AF at the index visit...
April 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29468958/impact-of-pre-procedural-cerebrovascular-events-on-clinical-outcomes-after-transcatheter-aortic-valve-implantation-in-patients-with-severe-aortic-stenosis
#18
Agata Wiktorowicz, Pawel Kleczynski, Artur Dziewierz, Tomasz Tokarek, Danuta Sorysz, Maciej Bagienski, Lukasz Rzeszutko, Dariusz Dudek
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is an increasingly common treatment of symptomatic severe aortic valve stenosis (AS). Thus, it is reasonable to carefully investigate the impact of individual clinical factors on outcomes after TAVI. OBJECTIVES: We aimed to investigate the impact of the previous cerebro-vascular events (CVEs) on outcomes of patients with severe AS undergoing TAVI. METHODS: A total of 148 consecutive patients scheduled for TAVI were included and stratified as with and without a history of CVEs (stroke or transient ischemic attack)...
February 19, 2018: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29457471/beck-depression-inventory-as-a-screening-tool-for-depression-in-chronic-haemodialysis-patients
#19
A Bautovich, I Katz, C K Loo, S B Harvey
OBJECTIVES: To evaluate the psychometric properties of the Beck Depression Inventory (BDI) and Cognitive Depression Index (CDI) as a potential screening tool for major depression in haemodialysis (HD) patients. METHODS: Forty-five HD patients completed both the BDI/CDI and diagnostic interview. The interview was conducted by two experienced clinicians and was based on DSM-IV criteria. The sensitivity, specificity and positive (PPV) and negative (NPV) predictive values were then calculated...
February 1, 2018: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/29440802/patients-with-end-stage-oncologic-and-nononcologic-disease-in-emergency-service-of-an-urban-tertiary-hospital
#20
Jose P Amado, Rolando Vasquez, Roberto W Huari, Andrea S Sucari, Teodoro J Oscanoa
Context: In the last decades, patients with chronic terminal diseases have had more frequent visits to emergency services. Aims: This study aims to determine the proportion of terminal illness in patients readmitted to emergency room, to evaluate the use of this service and rate of death. Settings and Design: A cross-sectional study in a tertiary hospital with 120 stretchers which annually reports 160 thousand attentions and 22 thousand admissions...
January 2018: Indian Journal of Palliative Care
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