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https://www.readbyqxmd.com/read/29519185/canal-wall-down-procedure-with-soft-posterior-meatal-wall-reconstruction-in-acquired-cholesteatoma-focus-on-postoperative-middle-ear-status
#1
Tomoyasu Tachibana, Shin Kariya, Yorihisa Orita, Michihiro Nakada, Takuma Makino, Yasutoshi Komatsubara, Yuko Matsuyama, Yuto Naoi, Kazunori Nishizaki
OBJECTIVES: We reviewed surgical results of canal wall-down tympanoplasty (CWDT) with soft posterior meatal wall reconstruction (SWR) for acquired cholesteatoma (AC), and identified factors associated with surgical outcomes. METHODS: Results from 119 ears with AC (pars flaccida, n = 99; pars tensa, n = 20) that underwent CWDT with SWR were retrospectively reviewed. We defined postoperative balloon-like retraction (PBR) with web formation, which needed reoperation to clean accumulated cerumen, as postoperative deep retraction pocket (PDRP)...
March 8, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29447898/challenges-and-outcomes-of-cholesteatoma-management-in-children-with-down-syndrome
#2
Saied Ghadersohi, Bharat Bhushan, Kathleen R Billings
INTRODUCTION: The high incidence of chronic otitis media with effusion and Eustachian tube dysfunction in children with Down syndrome (DS) may predispose them to cholesteatoma formation. Establishing the diagnosis, choosing the appropriate operative intervention, and post-operative care can be challenging. OBJECTIVE: To describe management strategies for cholesteatoma diagnosis, surgical treatment, and post-operative management in children with Down syndrome. METHODS: Retrospective case series of 14 patients (17 total ears) with Down syndrome diagnosed with cholesteatoma over a 9-year period...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447881/tympanostomy-tubes-for-serous-otitis-media-and-risk-of-recurrences
#3
Nathalie Klopp-Dutote, Catherine Kolski, Vladimir Strunski, Cyril Page
OBJECTIVES: To determine the value of tympanostomy tubes (TTs) in the management of serous otitis media (SOM) and the risk factors for SOM recurrence. METHOD: This single-centre cohort study was performed in the University hospital of Amiens, France; and concerned 215 under-12 children having undergone at least one bilateral TT (Shepard grommet-type) placements for SOM. RESULTS: The mean TT retention time was 10 months. SOM recurred in 79 children (62...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447810/no-evidence-of-cholesteatoma-in-untreated-otitis-media-with-effusion-in-children-with-primary-ciliary-dyskinesia
#4
Reshma Ghedia, Jahangir Ahmed, Annakan Navaratnam, Jonny Harcourt
INTRODUCTION: Primary Ciliary Dyskinesia (PCD) describes a group of inherited disorders that result in abnormal ciliary motion leading to mucous stasis. Clinical features include almost universally otitis media with effusion (OME), particularly in infants. PCD patients provide us with a cohort of patients with OME that is not treated with ventilatory tube (VT) insertion as these have been shown to result in frequent complications including chronic otorrhoea, early extrusion and persistent perforation without significant improvement to hearing in the long term...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29342049/the-impact-of-the-transcanal-endoscopic-approach-and-mastoid-preservation-on-recurrence-of-primary-acquired-attic-cholesteatoma
#5
Livio Presutti, Lukas Anschuetz, Alessia Rubini, Marco Ruberto, Matteo Alicandri-Ciufelli, Marco Dematte, Marco Caversaccio, Daniele Marchioni
OBJECTIVE: We aim to investigate the factors associated with recurrent disease following surgery for primary acquired attic cholesteatoma. We hypothesize that minimal invasive, mucosal sparing operation techniques have beneficial effects on the outcome in terms of recurrence. STUDY DESIGN: Retrospective study. SETTING: Tertiary referral center. PARTICIPANTS: A total of 110 patients presenting with primary acquired attic cholesteatoma were enrolled in the study...
January 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29327305/five-year-postoperative-outcomes-of-modified-staged-canal-wall-up-tympanoplasty-for-primary-acquired-cholesteatoma
#6
Masahiro Komori, Naoaki Yanagihara, Jun Hyodo, Ryosei Minoda, Yasuyuki Hinohira
OBJECTIVE: For successful canal wall up tympanoplasty (CWUT) for the treatment of cholesteatoma, the restoration of stable middle ear aeration is also important; however, little is known about the dynamics of such aeration or the optimal surgical procedure. In this study, alternative additional surgical procedure was selected based on the grade of middle ear aeration during the second-stage operation. SUBJECTS AND METHODS: Patients included in this study underwent staged CWUT surgeries with mastoid cortex plasty (MCP) for well-aerated ears (grade 3) and bony mastoid obliteration (BMO) for poorly aerated ears (grade 2-0)...
March 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29296957/%C3%AE-iib%C3%AE-3-binding-to-a-fibrinogen-fragment-lacking-the-%C3%AE-chain-dodecapeptide-is-activation-dependent-and-edta-inducible
#7
Hina Zafar, Yi Shang, Jihong Li, George A David, Joseph P Fernandez, Henrik Molina, Marta Filizola, Barry S Coller
Platelet integrin receptor αIIbβ3 supports platelet aggregation by binding fibrinogen. The interaction between the fibrinogen C-terminal γ-chain peptide composed of residues γ-404-411 (GAKQAGDV) and the Arg-Gly-Asp (RGD) binding pocket on αIIbβ3 is required for fibrinogen-mediated platelet aggregation, but data suggest that other ancillary binding sites on both fibrinogen and αIIbβ3 may lead to higher-affinity fibrinogen binding and clot retraction. To identify additional sites, we analyzed the ability of platelets and cells expressing normal and mutant αIIbβ3 to adhere to an immobilized fibrinogen plasmin fragment that lacks intact γ-404-411 ('D98')...
February 28, 2017: Blood Advances
https://www.readbyqxmd.com/read/29262385/-experience-and-solution-of-complications-of-vagus-nerve-stimulation-therapy-in-139-implant-patients-with-medically-refractory-epilepsy
#8
Daiki Uchida, Takamichi Yamamoto, Tomohiro Yamazoe, Kentaro Iijima, Ayataka Fujimoto, Hideo Enoki, Tokutaro Tanaka
BACKGROUND: Vagus nerve stimulation(VNS)for patients with intractable epilepsy was approved by the Japan Ministry of Health, Labour and Welfare in 2010. More than 1,500 VNS systems were implanted by the end of August 2016. The aim of the present report is to describe complications we experienced at our department and consider the way to avoid them. METHODS AND PATIENTS: We retrospectively reviewed 139 consecutive patients(122 new implantations and 17 reimplantations)between December 2010 and March 2016...
December 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29072240/the-role-of-the-nasal-and-paranasal-sinus-pathologies-on-the-development-of-chronic-otitis-media-and-its-subtypes-a-computed-tomography-study
#9
M Damar, A E Dinç, D Erdem, S Bişkin, S Ş Eliçora, Y Ç Kumbul
OBJECTIVE: This objective of this study is to evaluate the presence and the coincidence of common nasal and paranasal sinus pathologies in adults suffering from chronic otitis media (COM) and its subtypes. MATERIALS AND METHODS: The study group comprised 354 ears of 177 patients who underwent tympanoplasty with or without mastoidectomy from January 2013 to February 2015 due to uni/bilateral COM. Chronic suppurative otitis media, intratympanic tympanosclerosis (ITTS), cholesteatoma, and tympanic membrane with retraction pockets constituted subtypes of COM...
September 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28988463/evidence-against-the-mucosal-traction-theory-in-cholesteatoma
#10
Henrique F Pauna, Rafael C Monsanto, Patricia Schachern, Michael M Paparella, Richard A Chole, Sebahattin Cureoglu
OBJECTIVES: To investigate the distribution of ciliated epithelium in the human middle ear and its potential role in the formation of cholesteatoma. STUDY DESIGN: Comparative human temporal bone study. METHODS: We selected temporal bones from 14 donors with a diagnosis of cholesteatoma, 15 with chronic otitis media without retraction pockets, 14 with chronic otitis media with retraction pockets, 14 with cystic fibrosis (CF), and 16 controls...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28969634/socioeconomic-and-demographic-characterization-of-an-endemic-malaria-region-in-brazil-by-multiple-correspondence-analysis
#11
Raquel M Lana, Thais I S Riback, Tiago F M Lima, Mônica da Silva-Nunes, Oswaldo G Cruz, Francisco G S Oliveira, Gilberto G Moresco, Nildimar A Honório, Cláudia T Codeço
BACKGROUND: In the process of geographical retraction of malaria, some important endemicity pockets remain. Here, we report results from a study developed to obtain detailed community data from an important malaria hotspot in Latin America (Alto Juruá, Acre, Brazil), to investigate the association of malaria with socioeconomic, demographic and living conditions. METHODS: A household survey was conducted in 40 localities (n = 520) of Mâncio Lima and Rodrigues Alves municipalities, Acre state...
October 2, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28942628/postoperative-mastoid-aeration-following-canal-wall-up-mastoidectomy-according-to-preoperative-middle-ear-disease-analysis-of-temporal-bone-computed-tomography-scans
#12
Oh Joon Kwon, Jae Moon Sung, Hwi Kyeong Jung, Chang Woo Kim
BACKGROUND AND OBJECTIVES: The aim of our study was to evaluate postoperative mastoid aeration according to the preoperative middle ear disease and investigate the factors affecting it. SUBJECTS AND METHODS: We retrospectively reviewed the high-resolution computed tomography (CT) scans of temporal bones that were taken 1 year after surgery. The postoperative mastoid aeration was evaluated according to the preoperative diagnosis, and classified into three groups: grade 1 (complete mastoid aeration), an air-filled epitympanum and mastoid cavity; grade 2 (partial mastoid aeration), an air-filled epitympanum and partially aerated mastoid cavity; and grade 3 (absence of mastoid aeration), no air space in the mastoid cavity...
September 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28839422/clinical-and-radiographic-comparative-evaluation-of-buccal-and-palatal-corticotomy-with-buccal-corticotomy-in-periodontally-accelerated-osteogenic-orthodontics-with-surgical-bur
#13
Pavankumar Addanki, Jagadish Reddy Gooty, Rajababu Palaparthy
BACKGROUND: Periodontally accelerated osteogenic orthodontics is a clinical procedure that combines selective corticotomy, particulate grafting, and application of orthodontics. It reduces treatment time, increases stability of teeth, and prevents relapse of orthodontic tooth moment. The present study was aimed to explore the clinical and radiographic comparison of bone density changes, retraction time differences in buccal and palatal corticotomy with buccal corticotomy which was done by surgical bur...
April 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28672072/-blue-bubble-technique-an-ab-interno-approach-for-descemet-separation-in-deep-anterior-lamellar-keratoplasty-using-trypan-blue-stained-viscoelastic-device
#14
Eitan Livny, Irit Bahar, Naama Hammel, Yoav Nahum
BACKGROUND: In this study, we examined a novel variant of 'big-bubble' deep anterior lamellar keratoplasty using trypan-blue-stained viscoelastic device for the creation of a pre-descemetic bubble. METHODS: Ten corneoscleral rims were mounted on an artificial anterior chamber (AC). The AC was filled with air through a limbal paracentesis. A Melles' triangulated spatula was inserted through the paracentesis, with its tip penetrating the AC, was then slightly retracted and pushed into the deep stroma above the roof of the paracentesis...
July 3, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28497016/small-refinements-in-breast-reconstruction-a-technique-for-inframammary-fold-creation
#15
Arthur Ismagilov, Anna Vanesyan, Ilnur Kamaletdinov
BACKGROUND: In breast reconstructive surgery, the inframammary fold (IMF) is an essential component of breast identity. The lack of the IMF following previous mastectomy requires restoration. We have developed a new IMF reconstruction technique using the posterior sheet (PS) of the expander capsule. This article presents our 10-year experience of performing this original technique during two-stage breast reconstruction. METHODS: Preoperatively, the midline, lateral, and medial borders (MBs) of the implant pocket and the new IMF line were marked...
April 2017: Gland Surgery
https://www.readbyqxmd.com/read/28494066/association-between-middle-ear-cholesteatoma-and-chronic-rhinosinusitis
#16
Chin-Lung Kuo, Yu-Chun Yen, Wei-Pin Chang, An-Suey Shiao
Importance: Chronic rhinosinusitis (CRS) can cause an obstruction of the tubal orifice and thereby compromise ventilation of the middle ear. The resulting negative pressure in the middle ear may, in turn, lead to the formation of an eardrum retraction pocket and subsequent acquired cholesteatoma. This study hypothesizes that CRS may increase the risk of cholesteatoma. Objective: To evaluate the risk of cholesteatoma in patients with CRS. Design, Setting, and Participants: This study used a nationwide, population-based claims database to test the hypothesis that CRS may increase the risk of cholesteatoma...
August 1, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28485292/assessment-and-management-of-retraction-pockets
#17
Cuneyt Alper, Ewa Olszewska
This manuscript intends to review types, pathogenesis, associated risk factors, and potential methods of prevention and treatment of the retraction pockets in adults and children. The importance of retraction pockets (RP) lies in loss of original histological and anatomical structure which is associated with development of ossicular chain erosion, cho¬lesteatoma formation and potentially life threatening complications of cholesteatoma. The trans-mucosal exchange each gas in the middle ear (ME) is towards equalizing its partial pressures with the partial pressure in the environ¬ment...
February 28, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/28333779/impact-of-chronic-suppurative-otitis-media-in-pediatric-cochlear-implant-recipients-insight-into-the-challenges-from-a-tertiary-referral-center-in-uk
#18
Paramita Baruah, Kate Hanvey, Richard Irving, Konstance Tzifa
OBJECTIVE: Analyze the presentation and evolution of chronic suppurative otitis media (CSOM) in children with cochlear implants (CI) and explore the merit of early intervention. STUDY DESIGN: Retrospective patient review. SETTING: Tertiary referral hospital and cochlear implant programme. PATIENTS: Children with a CI who developed CSOM. INTERVENTION: Tympanoplasty. MAIN OUTCOME MEASURES: Disease control, recurrence of cholesteatoma, cochlear implant preservation...
June 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28325168/impact-of-pharyngofixation-in-cleft-palate-repair-surgery-on-the-development-of-chronic-adhesive-otitis-media
#19
L Otruba, P Schalek, Z Hornáčková
BACKGROUND: A significant percentage of children with cleft palate suffer from otitis media with effusion and its consequences, such as deafness, chronic adhesive otitis and cholesteatoma. This study aimed to determine whether these effects can be minimised by selecting pharyngofixation as the surgical technique for cleft palate correction. METHODS: A retrospective study was performed of 155 patients (308 ears) who underwent surgery from age 5 months to 8 years and were followed up for 36-84 months...
July 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28277483/endoscopy-assisted-ear-surgery-for-treatment-of-chronic-otitis-media-with-cholesteatoma-adhesion-or-retraction-pockets
#20
Cagatay Han Ulku
The objective of this study was to analyze the results of endoscopy-assisted ear surgery for the treatment of chronic otitis media with cholesteatoma, adhesion, or retraction pockets.Fifty-one patients who underwent oto-endoscopy-assisted canal wall up tympanomastoid surgery and/or limited anterior atticotomy with tympanoplasty for chronic otitis media with cholesteatoma, adhesion, or retraction pocket from 2006 to 2013 have been included in this study. Eradication of the disease from the middle ear and mastoid air cells was achieved by combination of the oto-microscobic and oto-endoscopic approaches...
June 2017: Journal of Craniofacial Surgery
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