keyword
MENU ▼
Read by QxMD icon Read
search

sudden unexpected death

keyword
https://www.readbyqxmd.com/read/28918379/infanrix-hexa-and-sudden-death-a-review-of-the-periodic-safety-update-reports-submitted-to-the-european-medicines-agency
#1
Jacob Puliyel, C Sathyamala
There have been a number of spontaneous reports of sudden unexpected death soon after the administration of Infanrix hexa (combined diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated poliomyelitis and Haemophilus influenza type B vaccine). The manufacturer, GlaxoSmithKline (GSK), submits confidential periodic safety update reports (PSURs) on Infanrix hexa to the European Medicines Agency (EMA). The latest is the PSUR 19. Each PSUR contains an analysis of observed/expected sudden deaths, which shows that the number of observed deaths soon after immunisation is lower than that expected by chance...
September 5, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28917499/association-of-sleep-with-sudden-unexpected-death-in-epilepsy
#2
REVIEW
Ahmer Ali, Shasha Wu, Naoum P Issa, Sandra Rose, Vernon L Towle, Peter Warnke, James X Tao
OBJECTIVE: The objective of this study was to determine the association of sleep with sudden unexpected death in epilepsy (SUDEP). METHODS: We conducted a systematic review and meta-analysis based on literature search from databases PubMed, Web of Science, and Scopus using keywords "SUDEP", or "sudden unexpected death in epilepsy", or "sudden unexplained death in epilepsy". Sudden unexpected death in epilepsy was considered to occur during sleep if the patient was found in bed, if the SUDEP cases were documented as in sleep, or if the patient was found at bedside on the bedroom floor...
September 13, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28917496/erratum-in-relation-of-household-income-to-incidence-of-sudden-unexpected-death-in-wake-county-north-carolina
#3
J Paul Mounsey
No abstract text is available yet for this article.
September 13, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28903333/effect-of-pkc-inhibitor-on-experimental-autoimmune-myocarditis-in-lewis-rats
#4
Chunlian Zhong, Yang Wu, He Chang, Chunxiao Liu, Li Zhou, Jun Zou, Zhi Qi
Myocarditis is a major cause of sudden, unexpected death in young people. However, it is still one of the most challenging diseases to treat in cardiology. In the present study, we showed that both expression level and activity of PKC-α were up-regulated in the rat heart of experimental autoimmune myocarditis (EAM). Intraperitoneal administration of PKC inhibitor (Ro-32-0432) at the end of the most severe inflammation period of EAM still significantly reduced the EAM induced expression of failure biomarkers...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28878049/reducing-placebo-exposure-in-trials-considerations-from-the-research-roundtable-in-epilepsy
#5
Brandy E Fureman, Daniel Friedman, Michel Baulac, Tracy Glauser, Jonathan Moreno, Tracy Dixon-Salazar, Emilia Bagiella, Jason Connor, Jim Ferry, Kathleen Farrell, Nathan B Fountain, Jacqueline A French
The randomized controlled trial is the unequivocal gold standard for demonstrating clinical efficacy and safety of investigational therapies. Recently there have been concerns raised about prolonged exposure to placebo and ineffective therapy during the course of an add-on regulatory trial for new antiepileptic drug approval (typically ∼6 months in duration), due to the potential risks of continued uncontrolled epilepsy for that period. The first meeting of the Research Roundtable in Epilepsy on May 19-20, 2016, focused on "Reducing placebo exposure in epilepsy clinical trials," with a goal of considering new designs for epilepsy regulatory trials that may be added to the overall development plan to make it, as a whole, safer for participants while still providing rigorous evidence of effect...
September 6, 2017: Neurology
https://www.readbyqxmd.com/read/28871835/peer-support-services-for-bereaved-survivors-a-systematic-review
#6
Paul T Bartone, Jocelyn V Bartone, John M Violanti, Zaneta M Gileno
This systematic literature review assesses the evidence regarding benefits of peer support services for bereaved survivors of sudden or unexpected death. Reports were included that addressed peer support services for adults who experienced death of a family member, close friend, or coworker. Of the 32 studies meeting all inclusion criteria, most showed evidence that peer support was helpful to bereaved survivors, reducing grief symptoms and increasing well-being and personal growth. Studies also showed benefits to providers of peer support, including increased personal growth and positive meaning in life...
January 1, 2017: Omega
https://www.readbyqxmd.com/read/28869205/ictal-asystole-in-a-patient-with-posterior-reversible-encephalopathy-syndrome-pres-and-seizures
#7
Joanna Suski, Reginald Ho, Maromi Nei
We describe a case of ictal asystole in a patient with posterior reversible encephalopathy syndrome (PRES), which has never been described previously. Ictal asystole is rare and has possible serious medical consequences, including syncope, and may be a potential mechanism for sudden unexpected death in epilepsy (SUDEP). Awareness that PRES may be observed with recurrent ictal asystole may aid in the recognition and treatment of seizures in this condition and the prevention of asystole-associated complications...
September 4, 2017: Epileptic Disorders: International Epilepsy Journal with Videotape
https://www.readbyqxmd.com/read/28868189/spontaneous-rupture-of-a-secondary-pituitary-abscess-causing-acute-meningoencephalitis-case-report-and-literature-review
#8
Giovanni Muscas, Francesco Iacoangeli, Laura Lippa, Biagio R Carangelo
BACKGROUND: Pituitary abscess (PA) is an uncommon finding that is rarely diagnosed preoperatively. If not properly treated it is associated with high morbidity and mortality rates. Nowadays standard diagnostic procedures allow early detection and successful treatment of this lesion in a high number of cases and mortality has been significantly reduced in recent years. PA arising de novo in a healthy gland are defined as primary, whereas those complicating a pre-existing disease of the hypophysis are called secondary abscesses...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28866704/unexpected-infant-death-secondary-to-a-pulmonary-infiltration-due-to-acute-myelocytic-leukaemia
#9
M Ben Khelil, Y Chkirbene, M Mlika, S Haouet, M Hamdoun
Acute myeloid leukaemia (AML) often presents with non-specific symptoms such as fatigue, anaemia or infection. Pulmonary involvement is uncommon in AML during the course of the disease and is usually caused by infection, haemorrhage, leukaemic pulmonary infiltrates and leukostasis. Lung localization of AML is very uncommon and potentially life threatening if not diagnosed and treated rapidly. The authors describe the sudden death of an asymptomatic five-month-infant because of a misdiagnosed lung localization of AML...
August 2017: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28844345/the-effect-of-atomoxetine-a-selective-norepinephrine-reuptake-inhibitor-on-respiratory-arrest-and-cardiorespiratory-function-in-the-dba-1-mouse-model-of-sudep
#10
Haiting Zhao, Joseph F Cotten, Xiaoyan Long, Hua-Jun Feng
Sudden unexpected death in epilepsy (SUDEP) is a significant public health burden. The mechanisms of SUDEP are elusive, although cardiorespiratory dysfunction is a likely contributor. Clinical and animal studies indicate that seizure-induced respiratory arrest (S-IRA) is the primary event leading to death in many SUDEP cases. Our prior studies demonstrated that intraperitoneal (IP) injection of atomoxetine, a norepinephrine reuptake inhibitor (NRI) widely used to treat attention deficit hyperactivity disorder, suppresses S-IRA in DBA/1 mice...
August 22, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28841792/-importance-of-the-forensic-autopsy-in-the-diagnosis-of-septic-shock-a-case-report
#11
A Sibón-Olano, E Sánchez-Rodríguez, M Payá, E Barrera-Pérez, M Salguero-Villadiego, A Fernández-Rodríguez
Septic shock sometimes starts with unspecific symptoms that hamper the clinical diagnosis and, therefore an appropriate treatment. When the septic shock follows a fulminating course with a fatal outcome, the etiological diagnosis has to be conducted post-mortem. Sudden unexpected deaths in children and young adults are frequently the object of medico-legal autopsies. Some sudden unexpected deaths have an infectious origin, which requires further analyses, including microbiology, to establish the cause of death...
August 25, 2017: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
https://www.readbyqxmd.com/read/28834541/sudden-unexpected-deaths-due-to-intracranial-meningioma-presentation-of-six-fatal-cases-review-of-the-literature-and-a-discussion-of-the-mechanisms-of-death
#12
Lorenzo Gitto, Giorgio Bolino, Stephen J Cina
Deaths due to meningiomas are routinely diagnosed in clinical practice because this neoplasm tends to present with the typical progression of neurological deficits. On the other hand, sudden unexpected deaths due to meningiomas are rarely described in the literature. The study presents six fatal cases of previously undiagnosed intracranial meningiomas from the Cook County Medical Examiner's Office from 1998 to 2014. The most common explanation of the mechanism of sudden death due to intracranial neoplasms is a rapid increase in intracranial pressure produced by the mass effect of the neoplasm...
August 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28814627/prematurity-and-sudden-unexpected-infant-deaths-in-the-united-states
#13
Barbara M Ostfeld, Ofira Schwartz-Soicher, Nancy E Reichman, Julien O Teitler, Thomas Hegyi
BACKGROUND AND OBJECTIVES: Prematurity, a strong risk factor for sudden unexpected infant death (SUID), was addressed in recommendations by the American Academy of Pediatrics in 2011 for safe sleep education in NICUs. We documented associations between gestational age (GA) and SUID subsequent to these guidelines. METHODS: Using the 2012-2013 US linked infant birth and death certificate period files, we documented rates per live births of sudden infant death syndrome, ill-defined and unspecified causes, accidental suffocation and strangulation in bed, and overall SUID by GA in postneonatal, out-of-hospital, and autopsied cases; compared survivors and cases; and estimated logistic regression models of associations between GA and SUID...
June 5, 2017: Pediatrics
https://www.readbyqxmd.com/read/28814625/variations-in-cause-of-death-determination-for-sudden-unexpected-infant-deaths
#14
Carrie K Shapiro-Mendoza, Sharyn E Parks, Jennifer Brustrom, Tom Andrew, Lena Camperlengo, John Fudenberg, Betsy Payn, Dale Rhoda
OBJECTIVES: To quantify and describe variation in cause-of-death certification of sudden unexpected infant deaths (SUIDs) among US medical examiners and coroners. METHODS: From January to November 2014, we conducted a nationally representative survey of US medical examiners and coroners who certify infant deaths. Two-stage unequal probability sampling with replacement was used. Medical examiners and coroners were asked to classify SUIDs based on hypothetical scenarios and to describe the evidence considered and investigative procedures used for cause-of-death determination...
June 5, 2017: Pediatrics
https://www.readbyqxmd.com/read/28811941/seizure-associated-takotsubo-syndrome-a-rare-combination
#15
Htay Htay Kyi, Nour Aljariri Alhesan, Sunil Upadhaya, Samer Al Hadidi
Takotsubo cardiomyopathy (TC) is increasingly recognized in neurocritical care population especially in postmenopausal females. We are presenting a 61-year-old African American female with past medical history of epilepsy, bipolar disorder, and hypertension who presented with multiple episodes of seizures due to noncompliance with antiepileptic medications. She was on telemetry which showed ST alarm. Electrocardiogram (ECG) was ordered and showed ST elevation in anterolateral leads and troponins were positive...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28810874/sudden-cardiac-death-focus-on-the-genetics-of-channelopathies-and-cardiomyopathies
#16
REVIEW
Simona Magi, Vincenzo Lariccia, Marta Maiolino, Salvatore Amoroso, Santo Gratteri
Sudden cardiac death (SCD) describes a natural and unexpected death from cardiac causes occurring within a short period of time (generally within 1 h of symptom onset) in the absence of any other potentially lethal condition. Most SCD-related diseases have a genetic basis; in particular congenital cardiac channelopathies and cardiomyopathies have been described as leading causes of SCD. Congenital cardiac channelopathies are primary electric disorders caused by mutations affecting genes encoding cardiac ion channels or associated proteins, whereas cardiomyopathies are related to mutations in genes encoding several categories of proteins, including those of sarcomeres, desmosomes, the cytoskeleton, and the nuclear envelope...
August 15, 2017: Journal of Biomedical Science
https://www.readbyqxmd.com/read/28810095/state-of-south-dakota-s-child-2016
#17
Ann L Wilson, Tyler Hemmingson, Brad Randall
In 2015, there was an increase in the number of births in South Dakota compared to the previous year. Further, the state's 2014 birth rate (14.4) exceeded the 12.5 rate observed nationally for this year. Similar to national trends, one-quarter of South Dakota newborns represent minority populations. The infant mortality rate of 7.3 for the state in 2015 was 24 percent higher than the 2014 rate. Analyses of factors that contributed to this increase show that twice as many infants died of sudden unexpected infant death (SUID) in 2015 as has been observed in previous years...
January 2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28807990/investigating-the-genetic-causes-of-sudden-unexpected-death-in-children-through-targeted-next-generation-sequencing-analysis
#18
Laura J Dewar, Miguel Alcaide, Daniel Fornika, Luisa D'Amato, Sanam Shafaatalab, Charles M Stevens, Thambirajah Balachandra, Susan M Phillips, Shubhayan Sanatani, Ryan D Morin, Glen F Tibbits
BACKGROUND: Inherited arrhythmia syndromes are responsible for a significant portion of autopsy-negative sudden unexpected death (SUD) cases, but molecular autopsy used to identify potentially causal variants is not routinely included in SUD investigations. We collaborated with a medical examiner's office to assist in finding a diagnosis for their autopsy-negative child SUD cases. METHODS AND RESULTS: 191 child SUD cases (<5 years of age) were selected for analyses...
August 2017: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/28806633/provision-of-sudden-unexpected-death-in-epilepsy-sudep-information-among-malaysian-parents-of-children-with-epilepsy
#19
Choong Yi Fong, Wei Kang Lim, Ann Nie Kong, Pei Lin Lua, Lai Choo Ong
Sudden unexpected death in epilepsy (SUDEP) is an important cause of mortality in epilepsy. To date, there is only one published UK study evaluating information provision of SUDEP among parents of children with epilepsy (CWE), and there are no studies published from Asia. Although SUDEP information provision is recommended among parents of CWE, it is uncertain if these recommendations are applicable to Asian countries due to the different cultural attitude towards epilepsy. Our prospective cohort study consisted of multiethnic parents of children with epilepsy (CWE) seen in a tertiary hospital in Malaysia...
August 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28806466/medicolegal-death-investigation-of-sudden-unexpected-infant-deaths
#20
Roger A Mitchell, Constance DiAngelo, Daniel Morgan
This review article describes the role of the medicolegal death investigator and medical examiner or coroner (MEC) in the investigations of a sudden unexpected infant death (SUID) beginning with an introduction into the case types that should be investigated and how infant deaths fit into that legal framework. The article also provides an overview of the history of the Centers for Disease Control and Prevention SUID investigation guidelines and process. The article concludes with a description of how the MEC correlates the scene investigation with autopsy findings, as well as the role of the MEC in cause of death determinations...
August 1, 2017: Pediatric Annals
keyword
keyword
89149
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"