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health-care associated pneumonia

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https://www.readbyqxmd.com/read/29776398/primary-bacterial-ventriculitis-in-adults-an-emergent-diagnosis-challenge-report-of-a-meningoccal-case-and-review-of-the-literature
#1
Anaïs Lesourd, Nicolas Magne, Anaïs Soares, Caroline Lemaitre, Muhamed-Kheir Taha, Isabelle Gueit, Michel Wolff, François Caron
BACKGROUND: Defined by an infection of the ventricular system of the brain, ventriculitis is usually known as a health-care associated infection. In contrast, primary pyogenic ventriculitis complicating community-acquired meningitis is uncommon, and mainly described in infants. Only seven cases that have occured in adults have been found in the international literature. CASE PRESENTATION: We report here a new case due to Neisseria meningitidis occurring in an 85 year-old-man...
May 18, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29775774/hospital-admissions-2000-2014-a-retrospective-analysis-of-288-096-events-in-patients-with-dementia
#2
Catarina Bernardes, João Massano, Alberto Freitas
INTRODUCTION: Dementia is a leading cause of disability worldwide. It is associated with an increased risk of hospitalization, imposing a significant burden on healthcare systems. The evidence on the long-term evolution of this issue and broadly on healthcare systems is currently limited. This study aims to describe the hospitalizations of people who received a diagnosis of dementia admitted to public general hospitals in a western European country with universal health coverage, over more than a decade...
May 8, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29762314/effectiveness-of-dexmedetomidine-versus-propofol-on-extubation-times-length-of-stay-and-mortality-rates-in-adult-cardiac-surgery-patients-a-systematic-review-and-meta-analysis
#3
John Nguyen, Noel Nacpil
OBJECTIVE: To determine the effects of dexmedetomidine versus propofol on extubation time, intensive care unit (ICU) length of stay, total hospital length of stay and in-hospital mortality rates in cardiac surgery patients. INTRODUCTION: Recovery from cardiovascular surgery involves weaning from mechanical ventilation. Mechanical ventilation decreases the work of breathing for patients by inhaling oxygen and exhaling carbon dioxide via a ventilator or breathing machine...
May 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29754841/-risks-associated-with-the-use-of-non-steroidal-anti-inflammatory-drugs-during-pneumonia
#4
REVIEW
G Voiriot, M Chalumeau, J Messika, D Basille, B Philippe, J-D Ricard, C Andrejak, V Jounieaux, O Sanchez, M Fartoukh
INTRODUCTION: Outpatient treatment of community-acquired pneumonia (CAP) patients with non-steroidal anti-inflammatory drugs (NSAIDs) is frequent, although this is not based on clinical recommendations and there is no scientific evidence supporting better symptom relief in comparison to acetaminophen. STATE OF THE ART: Experimental data suggest that NSAIDs alter the intrinsic functions of neutrophils, limit their locoregional recruitment, alter bacterial clearance and delay the resolution of inflammatory processes during acute bacterial pulmonary challenge...
May 10, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29750043/analysis-of-acinetobacter-baumannii-hospital-infections-in-patients-treated-at-the-intensive-care-unit-of-the-university-hospital-wroclaw-poland-a-6-year-single-center-retrospective-study
#5
Wieslawa Duszynska, Agnieszka Litwin, Stanislaw Rojek, Aleksander Szczesny, Alfonso Ciasullo, Waldemar Gozdzik
Background: Acinetobacter baumannii (AB) is one of the most frequently isolated strains of bacteria in intensive care unit (ICU) patients, which provides huge therapeutic problems due to its multidrug resistance (MDR). Patients and methods: The overall purpose of the study was analysis of health care- associated infections in terms of the incidence of AB strain infections and the changing susceptibility of this strain within a 6-year observation (2011-2016). The study was carried out in an ICU of the University Hospital in Wroclaw (Poland)...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29743218/living-in-cold-spot-communities-is-associated-with-poor-health-and-health-quality
#6
Winston Liaw, Alex H Krist, Sebastian T Tong, Roy Sabo, Camille Hochheimer, Jennifer Rankin, David Grolling, Jene Grandmont, Andrew W Bazemore
PURPOSE: Little is known about incorporating community data into clinical care. This study sought to understand the clinical associations of cold spots (census tracts with worse income, education, and composite deprivation). METHODS: Across 12 practices, we assessed the relationship between cold spots and clinical outcomes (obesity, uncontrolled diabetes, pneumonia vaccination, cancer screening-colon, cervical, and prostate-and aspirin chemoprophylaxis) for 152,962 patients...
May 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29739652/prolonged-length-of-stay-for-acute-hospital-admissions-as-the-increasing-of-age-a-nationwide-population-study-for-taiwan-s-patients-with-cerebral-palsy
#7
Kuo-Liang Chiang, Chin-Yin Huang, Hueng-Chuen Fan, Fang-Chuan Kuo
BACKGROUND: Studies investigating reasons for the admission and the associated lengths of stay (LOSs) among cerebral palsy (CP) patients are limited. This study determined common reasons for acute hospitalizations and the LOSs among children, adolescents, and young adults with CP. METHODS: We performed a secondary analysis of data. CP patients aged 4-32.9 years were identified by CP registry in the catastrophic illness patient registry of the 2010 Taiwan National Health Insurance Research Database...
April 12, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29728084/group-b-streptococci-vaginal-colonization-and-drug-susceptibility-pattern-among-pregnant-women-attending-in-selected-public-antenatal-care-centers-in-addis-ababa-ethiopia
#8
Solomon Assefa, Kassu Desta, Tsehaynesh Lema
BACKGROUND: Group B Streptococcus (GBS) is the leading cause of septicemia, meningitis, and pneumonia in neonates. Maternal colonization with GBS is the principal risk factor for early-onset disease in infants. Group B Streptococcus is now an important cause of maternal and neonatal morbidity and mortality in many parts of the world. In Ethiopia, few studies have been done on GBS colonization among pregnant women. The aim of this study was to determine the prevalence of GBS colonization, antimicrobial susceptibility patterns and assess risk factors among pregnant women...
May 4, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29724618/missed-opportunities-in-the-diagnosis-of-human-immunodeficiency-virus-infection-in-the-region-of-aragon-late-diagnosis-importance
#9
César Gargallo-Bernad, Francisco Javier Sangrós-González, Piedad Arazo-Garcés, Rosa Martínez-Álvarez, Carmen Malo-Aznar, Alicia Gargallo-Bernad, Alba Ballester-Luna, Luis Eduardo Cabrero-Pascual, Pablo Gil-Orna, Víctor José Abadía-Gallego, Isabel Torres-Peña, Héctor Ordiz-Suárez
INTRODUCTION: Late Diagnosis (LD) of Human Immunodeficiency Virus (HIV) infection (CD4 lymphocytes <350/μl at diagnosis of the disease), deteriorates the condition of those affected and increases the probability of transmission. The objective of the present study was to analyse the prevalence of LD, to identify missed diagnostic opportunities (MDO) and to find out which level of the health care delivery system they took place. METHODS: Retrospective, observational and descriptive study of the population diagnosed with infection of HIV/AIDS in the period 2011-2015 in Aragon...
April 30, 2018: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/29722334/antibiotics-de-escalation-in-the-treatment-of-ventilator-associated-pneumonia-in-trauma-patients-a-retrospective-study-on-propensity-score-matching-method
#10
Hu Li, Chun-Hui Yang, Li-Ou Huang, Yu-Hui Cui, Dan Xu, Chun-Rong Wu, Jian-Guo Tang
Background: Antimicrobial de-escalation refers to starting the antimicrobial treatment with broad-spectrum antibiotics, followed by narrowing the drug spectrum according to culture results. The present study evaluated the effect of de-escalation on ventilator-associated pneumonia (VAP) in trauma patients. Methods: This retrospective study was conducted on trauma patients with VAP, who received de-escalation therapy (de-escalation group) or non-de-escalation therapy (non-de-escalation group)...
May 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29703009/acute-respiratory-failure-requiring-mechanical-ventilation-in-severe-chronic-obstructive-pulmonary-disease-copd
#11
Shruti K Gadre, Abhijit Duggal, Eduardo Mireles-Cabodevila, Sudhir Krishnan, Xiao-Feng Wang, Katrina Zell, Jorge Guzman
There are limited data on the epidemiology of acute respiratory failure necessitating mechanical ventilation in patients with severe chronic obstructive pulmonary disease (COPD). The prognosis of acute respiratory failure requiring invasive mechanical ventilation is believed to be grim in this population. The purpose of this study was to illustrate the epidemiologic characteristics and outcomes of patients with underlying severe COPD requiring mechanical ventilation.A retrospective study of patients admitted to a quaternary referral medical intensive care unit (ICU) between January 2008 and December 2012 with a diagnosis of severe COPD and requiring invasive mechanical ventilation for acute respiratory failure...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29699825/chronic-obstructive-pulmonary-disease-is-associated-with-short-term-complications-following-total-knee-arthroplasty
#12
George A Yakubek, Gannon L Curtis, Anton Khlopas, Mhamad Faour, Alison K Klika, Michael A Mont, Wael K Barsoum, Carlos A Higuera
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major global health issue and a leading cause of morbidity and mortality. Patients with COPD are at increased risk of complications following surgery. The purpose of this study is to evaluate the postoperative total knee arthroplasty (TKA) outcomes in these patients in comparison to a non-COPD matching cohort. Specifically, we asked the following questions: (1) "Is COPD associated with adverse perioperative outcomes?" and (2) "Does COPD increase the risk of short-term complications following TKA?" METHODS: The American College of Surgeons National Surgical Quality Improvement Program database was used to identify 111,168 patients who underwent TKA between 2008 and 2014...
March 15, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29699468/lower-respiratory-tract-infection-and-short-term-outcome-in-patients-with-acute-respiratory-distress-syndrome
#13
Fernando G Zampieri, Pedro Póvoa, Jorge I Salluh, Alejandro Rodriguez, Sandrine Valade, José Andrade Gomes, Jean Reignier, Elena Molinos, Jordi Almirall, Nicolas Boussekey, Lorenzo Socias, Paula Ramirez, William N Viana, Anahita Rouzé, Saad Nseir, Ignacio Martin-Loeches
OBJECTIVE: To assess whether ventilator-associated lower respiratory tract infections (VA-LRTIs) are associated with mortality in critically ill patients with acute respiratory distress syndrome (ARDS). MATERIALS AND METHODS: Post hoc analysis of prospective cohort study including mechanically ventilated patients from a multicenter prospective observational study (TAVeM study); VA-LRTI was defined as either ventilator-associated tracheobronchitis (VAT) or ventilator-associated pneumonia (VAP) based on clinical criteria and microbiological confirmation...
January 1, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29696083/health-care-resource-utilization-and-characteristics-of-patients-with-eosinophilic-asthma-in-secondary-health-care-in-finland
#14
Mika J Mäkelä, Helene Nordahl Christensen, Antti Karlsson, Sarang Rastogi, Kirsi Kettunen
Background : Eosinophilic airway inflammation is common in asthma patients and appears to be associated with severe exacerbations and loss of asthma control. Objective : To describe the resource utilization and clinical characteristics of patients with eosinophilic asthma. Design : Asthma patients ≥18 years with ≥1 blood eosinophil count in secondary care (South West Finland) during 2003‒2013 were included. Clinical characteristics (age, lung function, body mass index, and comorbidities) and asthma-related resource utilization (hospital admissions, outpatient visits, and emergency room [ER] visits) were retrieved...
2018: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29681942/bacterial-profile-antibacterial-resistance-pattern-and-associated-factors-from-women-attending-postnatal-health-service-at-university-of-gondar-teaching-hospital-northwest-ethiopia
#15
Abebaw Bitew Kifilie, Mulat Dagnew, Birhanemeskel Tegenie, Biruk Yeshitela, Rawleigh Howe, Ebba Abate
Introduction: Surgical site infection is a vital cause of maternal mortality and morbidity, especially in resource-limited countries. The rise of antibiotic resistance bacterial infection poses a big threat to this vulnerable population. However, there is lack of studies around the study area. Objective: The purpose of this study was to identify bacterial profile, antibacterial resistance pattern, and associated factors among mothers attending postnatal care health service...
2018: International Journal of Microbiology
https://www.readbyqxmd.com/read/29680945/cilostazol-is-effective-to-prevent-stroke-associated-pneumonia-in-patients-receiving-tube-feeding
#16
Shizuka Netsu, Atsushi Mizuma, Masaki Sakamoto, Sachiko Yutani, Eiichiro Nagata, Shunya Takizawa
Stroke-associated pneumonia (SAP) is a frequent complication in acute ischemic stroke (IS) patients, especially those receiving tube feeding (TF). In this retrospective study, we investigated whether or not cilostazol, a pluripotent phosphodiesterase III-specific inhibitor with anti-platelet and vasculogenic effects, can prevent SAP in these patients and reduce their duration of stay in intensive care unit/hospitalization. We recruited 158 IS patients receiving TF. Patients' characteristics (including age, gender, past history), National Institute of Health Stroke Scale and serum albumin level on admission, concomitant medications associated with SAP prevention (including cilostazol), and stroke characteristics (bilateral subcortical white matter lesion, brainstem involvement, large infarction, and asymptomatic hemorrhagic infarction) were compared between the SAP(-) and SAP(+) groups...
April 21, 2018: Dysphagia
https://www.readbyqxmd.com/read/29662688/distribution-and-determinants-of-pneumonia-diagnosis-using-integrated-management-of-childhood-illness-guidelines-a-nationally-representative-study-in-malawi
#17
Omolara T Uwemedimo, Todd P Lewis, Elsie A Essien, Grace J Chan, Humphreys Nsona, Margaret E Kruk, Hannah H Leslie
Background: Pneumonia remains the leading cause of child mortality in sub-Saharan Africa. The Integrated Management of Childhood Illness (IMCI) strategy was developed to standardise care in low-income and middle-income countries for major childhood illnesses and can effectively improve healthcare worker performance. Suboptimal clinical evaluation can result in missed diagnoses and excess morbidity and mortality. We estimate the sensitivity of pneumonia diagnosis and investigate its determinants among children in Malawi...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29661625/unusual-presentation-of-middle-east-respiratory-syndrome-coronavirus-leading-to-a-large-outbreak-in-riyadh-during-2017
#18
Hala Amer, Abdulrahman S Alqahtani, Hind Alzoman, Nawfal Aljerian, Ziad A Memish
BACKGROUND: The hallmark of Middle East respiratory syndrome coronavirus (MERS-CoV) disease is the ability to cause major health care-associated nosocomial outbreaks with superspreading events leading to massive numbers of cases and excessive morbidity and mortality. In this report, we describe a patient who presented with acute renal failure requiring hemodialysis and became a MERS-CoV superspreader, igniting a recent multihospital outbreak in Riyadh. MATERIAL AND RESULTS: Between May 31 and June 15, 2017, 44 cases of MERS-CoV infection were reported from 3 simultaneous clusters from 3 health care facilities in Riyadh, Saudi Arabia, including 11 fatal cases...
April 13, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29617698/pseudomonas-aeruginosa-and-klebsiella-pneumoniae-adaptation-to-innate-immune-clearance-mechanisms-in-the-lung
#19
Sebastian A Riquelme, Danielle Ahn, Alice Prince
Many different species of gram-negative bacteria are associated with infection in the lung, causing exacerbations of chronic obstructive pulmonary disease, cystic fibrosis (CF), and ventilator-associated pneumonias. These airway pathogens must adapt to common host clearance mechanisms that include killing by antimicrobial peptides, antibiotics, oxidative stress, and phagocytosis by leukocytes. Bacterial adaptation to the host is often evident phenotypically, with increased extracellular polysaccharide production characteristic of some biofilm-associated organisms...
April 4, 2018: Journal of Innate Immunity
https://www.readbyqxmd.com/read/29609489/long-term-sequelae-of-acute-respiratory-distress-syndrome-caused-by-severe-community-acquired-pneumonia-delirium-associated-cognitive-impairment-and-post-traumatic-stress-disorder
#20
Claudia Denke, Felix Balzer, Mario Menk, Sebastian Szur, Georg Brosinsky, Sascha Tafelski, Klaus-Dieter Wernecke, Maria Deja
Objective Delirium in critically ill patients is considered a risk factor for various long-term consequences. We evaluated delirium and associated long-term outcomes in patients with acute respiratory distress syndrome with non-H1N1 and H1N1- associated severe community-acquired pneumonia (sCAP) who had been recommended to take antiviral drugs associated with delirious symptoms as adverse effects. Methods Of 64 patients, 42 survivors (H1N1, 15; non-H1N1, 27) were analyzed regarding the relationship between medication and the duration of delirium in the intensive care unit...
January 1, 2018: Journal of International Medical Research
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