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Tendon Repair

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https://www.readbyqxmd.com/read/29231990/tendon-explant-cultures-to-study-the-communication-between-adipose-stem-cells-and-native-tendon-niche
#1
Raquel Costa-Almeida, Dominika Berdecka, Márcia T Rodrigues, Rui L Reis, Manuela E Gomes
Poor clinical outcomes of tendon repair, together with limited regenerative capacity of the tissue, have triggered the search for alternative regenerative medicine strategies. Human adipose-derived stem cells (hASCs) are being investigated as a promising cell source in contributing for tendon repopulation and reconstruction. However, the mechanisms involved in a potential beneficial effect in tendon regeneration are still to be uncovered. To gain further insights on the bi-directional crosstalk occurring between stem cells and the native tendon niche, it was used an indirect (trans-well) system for co-culturing human tendon explants and hASCs...
December 12, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29228408/-biomechanical-evaluation-of-rehabilitation-after-surgical-repair-of-achilles-tendon-ruptures
#2
Marlene Mauch, Markus Ulrich, Xaver Kaelin, Bernhard Segesser, Jochen Paul
Background Muscles and tendons are subjected to a high level of stress in everyday life and sports. This often leads to injuries and is associated with training failure and reduced performance as well as with high costs for treatment and rehabilitation. Fast and successful treatment is therefore very important, both from an athletic and economic point of view. This study aims to demonstrate the relevance of biomechanical procedures for the objective monitoring of rehabilitation. At the same time, the results are to be used to establish progress and evaluation criteria for an efficient and controlled rehabilitation...
December 2017: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
https://www.readbyqxmd.com/read/29223409/obtaining-adequate-tension-for-extensor-hallucis-longus-tendon-rupture-repair-using-wide-awake-surgery-a-case-report
#3
Takenori Matsuda, Akira Taniguchi, Koji Hayashi, Yasuaki Nakanishi, Yasuhito Tanaka
Wide-awake surgery has potential advantages for treating extensor or flexor tendon injury. We present a case of chronic extensor hallucis longus injury treated with turn-down reconstruction using wide-awake surgery with a selective nerve block. To the best of our knowledge, this is the first such case reported. The patient had dropped a knife proximal to the right hallux metatarsophalangeal joint. Because direct suturing was thought to be difficult, turn-down reconstruction was performed under a selective nerve block...
December 7, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29218649/treatment-of-flexor-tendon-reconstruction-failures-multicentric-experience-with-brunelli-active-tendon-implant
#4
A Poggetti, M Novi, M Rosati, D Ciclamini, M Scaglione, B Battiston
INTRODUCTION: Secondary repair of flexor tendon injuries remain a challenging procedure for hand surgeons. Usually, secondary reconstruction should be performed by staged approach. When the tendon and pulley integrity are intact, tenolysis may be the first surgical option. One-/two-stage tendon grafts are suggested when the integrity of flexor tendon is compromised. Active tendon implants (Brunelli prostheses) may represent an efficient option in patients with a poor prognosis, as well as whenever classical techniques fail...
December 7, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29216702/-sonographic-evaluation-of-achilles-tendon-healing-in-tenotomies-for-congenital-clubfoot-and-ponsetis-treatment-a-12-week-follow-up
#5
J G Ríos-Ruiz, D M González-Torres, L A Valdez-Jiménez
OBJECTIVE: The aim of this study was to determine the healing time of Achilles tendon in pediatric patients treated with Achilles tenotomy with the Ponseti method in Shriners Childrens Hospital of Mexico, AC. MATERIAL AND METHODS: Experimental, analytical, prospective, longitudinal study of patients with a diagnosis of idiopathic congenital clubfoot treated with the Ponseti method with serial static and dynamic evaluation by ultrasound in real time with a Siemens Diagnostic Ultrasound System Sonoline 650, linear transducer 10...
May 2017: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/29212686/practice-patterns-in-the-care-of-acute-achilles-tendon-ruptures-is-there-an-association-with-level-i-evidence
#6
U Sheth, D Wasserstein, R Jenkinson, R Moineddin, H Kreder, S Jaglal
AIMS: To determine whether the findings from a landmark Canadian trial assessing the optimal management of acute rupture of the Achilles tendon influenced the practice patterns of orthopaedic surgeons in Ontario, Canada. MATERIALS AND METHODS: Health administrative databases were used to identify Ontario residents ≥ 18 years of age with an Achilles tendon rupture from April 2002 to March 2014. The rate of surgical repair (per 100 cases) was calculated for each calendar quarter...
December 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/29210159/safety-of-mtor-inhibitor-continuation-in-pediatric-heart-transplant-recipients-undergoing-surgical-procedures
#7
Ann Heble, Melanie D Everitt, Jane Gralla, Shelley D Miyamoto, Michael Lahart, Jennifer Eshelman
mTOR inhibitors have been associated with SWC when used in the perioperative period. Limited literature is available to guide providers in managing chronic mTOR inhibitor use in the perioperative period, especially in the pediatric setting. The primary aim of this study was to describe the prevalence of SWC with mTOR inhibitor continuation during the perioperative period for major surgeries. Heart transplant recipients ≤25 years old at the time of primary heart transplant receiving sirolimus maintenance therapy during a surgical procedure and within the study period were included...
December 6, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29209417/do-athletes-alter-their-running-mechanics-after-an-achilles-tendon-rupture
#8
Daniel Jandacka, Julia Freedman Silvernail, Jaroslav Uchytil, David Zahradnik, Roman Farana, Joseph Hamill
Background: Over the past thirty years, there has been dramatic increase in incidence of Achilles tendon rupture in the athletic population. The purpose of this study was to compare the lower extremity mechanics of Achilles tendon ruptured runners with healthy controls. Methods: The participants with a past history of an Achilles tendon repair (n = 11) and healthy control (n = 11) subgroups were matched on sex, age, type of regular physical activity, mass, height, footfall pattern and lateral dominancy...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29202765/a-novel-technique-for-modified-all-inside-repair-of-bucket-handle-meniscus-tears-using-standard-arthroscopic-portals
#9
Jing Hui Yik, Bryan Thean Howe Koh, Wilson Wang
BACKGROUND: Bucket-handle meniscus tears (BHMT) are often displaced and unstable. The inside-out technique of repairing such tears is currently the gold standard. All-inside repair with meniscal fixators is getting increasingly popular. Shortcomings of the inside-out technique include neurovascular complications, especially saphenous nerve palsy, and retention of a non-resorbable suture which can result in discomfort to patient, granuloma formation, and a foci of infection. Hence, the purpose of this project was to innovate a novel all-inside technique to precisely reduce and fix BHMT while avoiding neurovascular complications and retention of a non-resorbable suture...
December 4, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29199471/outcomes-of-triceps-rupture-in-the-us-military-minimum-2-year-follow-up
#10
John C Dunn, Nicholas Kusnezov, Austin Fares, Kelly Kilcoyne, E'stephan Garcia, Justin D Orr, Brian R Waterman
BACKGROUND: The objective of this study was to examine the subjective and objective midterm functional clinical outcomes of surgically repaired triceps injuries in a moderate- to high-demand population. METHODS: The US Military Health System was queried to identify all surgically treated triceps tendon ruptures between 2008 and 2013. Primary endpoints included rates of rerupture, perioperative complications, or significant persistent elbow dysfunction; Disability of the Arm, Shoulder and Hand (DASH) score, Mayo Elbow score, and ability to do push-ups were also extracted...
December 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29191201/single-versus-double-row-suture-anchor-fixation-for-greater-tuberosity-fractures-a-biomechanical-study
#11
Gernot Seppel, Tim Saier, Frank Martetschläger, Johannes E Plath, Alberto Guevara-Alvarez, Julia Henschel, Martin Winkler, Peter Augat, Andreas B Imhoff, Stefan Buchmann
BACKGROUND: Fractures of the humeral greater tuberosity (GT) are a frequent injury progressively treated with arthroscopic suture anchor repair. Yet, no biomechanical study has been performed comparing fixation strength of arthroscopic single- (SR) vs. double row (DR) fixation. METHODS: Standardized fractures of the greater tuberosity were created in 12 fresh frozen proximal humeri. After random assignation to the SR or DR group the fixed humeri were tested applying cyclic loading to the supraspinatus and infraspinatus tendon...
December 1, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29189618/bilateral-patellar-tendon-rupture
#12
Mary Kamienski
The knee is the most complex and largest joint in the body. Injuries to any part of this joint affect the entire body. There are multiple injuries that can occur to the knee, with the most common being ligament and meniscus tears. A not-so-common injury to the knee is a patellar tendon rupture. A bilateral patellar tendon rupture is extremely rare. A case study of a 43-year-old man who sustained a bilateral patellar tendon rupture while playing softball is used to present this devastating injury. This discussion includes the incidence and diagnosis of the tear, surgical repair, as well as a description of the comprehensive rehabilitation process necessary to allow the patient to return to normal physical activity...
November 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/29183690/home-based-intravenous-analgesia-with-elastomeric-pump-as-an-outpatient-procedure-for-pain-control-after-anterior-cruciate-ligament-repair
#13
J Villalba, J Peñalver, P Torner, M Serra, J Planell
OBJECTIVE: To follow up pain in the immediate postoperative period, using an elastomeric pump in anterior cruciate ligament surgery. MATERIAL AND METHODS: 309 patients who had undergone anterior cruciate ligament repair with bone-tendon-bone allograft. Pain control was assessed with a visual analogue scale (VAS) during the immediate postoperative period, in the postoperative care unit, in the recovery room, and after the first 24-48-72hours following home discharge...
November 25, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/29174694/synergistic-promoting-effects-of-bone-morphogenetic-protein-12-connective-tissue-growth-factor-on-functional-differentiation-of-tendon-derived-stem-cells-and-patellar-tendon-window-defect-regeneration
#14
Kang Xu, Yanjun Sun, Mohanad Kh Al-Ani, Chunli Wang, Yongqiang Sha, Kl Paul Sung, Nianguo Dong, Xuefeng Qiu, Li Yang
Current study investigated bone morphogenetic protein 12 (BMP12) and connective tissue growth factor (CTGF) activate tendon derived stem cells (TDSCs) tenogenic differentiation, and promotion of injured tendon regeneration. TDSCs were transfected with BMP12 and CTGF via recombinant adenovirus (Ad) infection. Gene transfection efficiency, cell viability and cytotoxicity, tenogenic gene expression, collagen I/III synthesis were evaluated in vitro. For the in vivo study, the transfected cells were transplanted into the rat patellar tendon window defect...
November 7, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29174271/effects-of-pulsed-electromagnetic-field-therapy-at-different-frequencies-and-durations-on-rotator-cuff-tendon-to-bone-healing-in-a-rat-model
#15
Julianne Huegel, Daniel S Choi, Courtney A Nuss, Mary C C Minnig, Jennica J Tucker, Andrew F Kuntz, Erik I Waldorff, Nianli Zhang, James T Ryaby, Louis J Soslowsky
BACKGROUND: Rotator cuff tears affect millions of individuals each year, often requiring surgical intervention. However, repair failure remains common. We have previously shown that pulsed electromagnetic field (PEMF) therapy improved tendon-to-bone healing in a rat rotator cuff model. The purpose of this study was to determine the influence of both PEMF frequency and exposure time on rotator cuff healing. METHODS: Two hundred ten Sprague-Dawley rats underwent acute bilateral supraspinatus injury and repair followed by either Physio-Stim PEMF or high-frequency PEMF therapy for 1, 3, or 6 hours daily...
November 22, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29169630/kinetic-analysis-of-canine-gait-on-the-effect-of-failure-tendon-repair-and-tendon-graft
#16
Yu-Shiuan Cheng, Ramona Reisdorf, Alyssa Vrieze, Steven L Moran, Peter C Amadio, Kai-Nan An, Chunfeng Zhao
Kinetic analysis of canine gait has been extensively studied, including normal and abnormal gait. However, no research has looked into how flexor tendon injury and further treatment would affect the walking pattern comparing to the uninjured state. Therefore, this study was aimed to utilize a portable pressure walkway system, which has been commonly used for pedobarographic and kinetic analysis in the veterinary field, to examine the effect of a failed tendon repair and tendon graft reconstruction on canine digit kinetics during gait...
November 20, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29166912/neurofilament-distribution-in-the-superior-labrum-and-the-long-head-of-the-biceps-tendon
#17
Sandra Boesmueller, Antal Nógrádi, Patrick Heimel, Christian Albrecht, Sylvia Nürnberger, Heinz Redl, Christian Fialka, Rainer Mittermayr
BACKGROUND: The postoperative course after arthroscopic superior labrum anterior to posterior (SLAP) repair using suture anchors is accompanied by a prolonged period of pain, which might be caused by constriction of nerve fibres. The purpose was to histologically investigate the distribution of neurofilament in the superior labrum and the long head of the biceps tendon (LHBT), i.e. the location of type II SLAP lesions. METHODS: Ten LHBTs including the superior labrum were dissected from fresh human specimen and immunohistochemically stained against neurofilament (NF)...
November 22, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29166314/step-cut-lengthening-a-technique-for-treatment-of-flexor-pollicis-longus-tendon-rupture
#18
Chew-Wei Chong, Shih-Heng Chen
Reconstruction of a tendon defect is a challenging task in hand surgery. Delayed repair of a ruptured flexor pollicis longus (FPL) tendon is often associated with tendon defect. Primary repair of the tendon is often not possible, particularly after debridement of the unhealthy segment of the tendon. As such, various surgical treatments have been described in the literature, including single-stage tendon grafting, 2-stage tendon grafting, flexor digitorum superficialis tendon transfer from ring finger, and interphalangeal joint arthrodesis...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29166259/clinical-outcome-of-achilles-tendon-repair-using-viable-intact-cryopreserved-umbilical-tissue-versus-standard-of-case
#19
John Brandeisky, Dorothy H Kurtz Phelan
INTRODUCTION: Repair of acute Achilles tendon ruptures is complicated by the severity of the rupture, quality of the tendon, and length of the defect. The adjunct use of biologics (eg, viable umbilical tissue) may provide additional support and reduce postoperative inflammation, adhesions, and fibrosis. OBJECTIVE: The aim of this study is to review the outcomes of Achilles tendon rupture open repairs with viable cryopreserved umbilical tissue (vCUT) compared with patients treated with standard of care only...
November 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29164105/platelet-rich-plasma-derived-growth-factors-contribute-to-stem-cell-differentiation-in-musculoskeletal-regeneration
#20
REVIEW
Yun Qian, Qixin Han, Wei Chen, Jialin Song, Xiaotian Zhao, Yuanming Ouyang, Weien Yuan, Cunyi Fan
Stem cell treatment and platelet-rich plasma (PRP) therapy are two significant issues in regenerative medicine. Stem cells such as bone marrow mesenchymal stem cells, adipose-derived stem cells and periodontal ligament stem cells can be successfully applied in the field of tissue regeneration. PRP, a natural product isolated from whole blood, can secrete multiple growth factors (GFs) for regulating physiological activities. These GFs can stimulate proliferation and differentiation of different stem cells in injury models...
2017: Frontiers in Chemistry
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