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Tendon Repair

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https://www.readbyqxmd.com/read/28527190/tight-medial-knot-tying-may-increase-retearing-risk-after-transosseous-equivalent-repair-of-rotator-cuff-tendon
#1
Hirotaka Sano, Masako Tokunaga, Moriyuki Noguchi, Takashi Inawashiro, Taichi Irie, Hiroo Abe, A Toshimitsu Yokobori
BACKGROUND: Retearing mechanism after transosseous equivalent (TOE) rotator cuff repair has not been fully clarified yet. OBJECTIVE: The purposes of this study were to compare the stress distribution pattern in the tendon stump between knotted and knotless TOE repair and to investigate the role of suture tension applied during medial knot tying using a 3-dimensional finite element (3D-FE) method. METHODS: Both knotted and knotless TOE repairs were simulated on the 3D-FE human rotator cuff tear model...
2017: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/28526996/improved-outcomes-with-arthroscopic-repair-of-partial-thickness-rotator-cuff-tears-a-systematic-review
#2
J Christoph Katthagen, Gabriella Bucci, Gilbert Moatshe, Dimitri S Tahal, Peter J Millett
PURPOSE: The optimum treatment strategy for the surgical management of partial-thickness rotator cuff tears (PTRCT) is evolving. In this study, two research questions were sought to be answered: "Does the repair technique for PTRCTs involving >50% of the tendon thickness have an effect on structural and functional outcomes of arthroscopic repair?" and "Is there a difference in outcomes of arthroscopically treated articular- and bursal-sided PTRCTs?". METHODS: A systematic review according to the PRISMA statement was conducted to identify all literature published reporting on outcomes of arthroscopic treatment of PTRCTs classified with the Ellman classification with minimum 2-year follow-up...
May 19, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28526421/delayed-repair-of-distal-biceps-tendon-ruptures-is-successful-a-case-control-study
#3
John Haverstock, Ruby Grewal, Graham J W King, George S Athwal
BACKGROUND: The literature has shown an increased complication rate with a delay to surgical repair of acute distal biceps tendon ruptures; however, little has been documented regarding the outcome of delayed repairs. This case-control study compared a study cohort of delayed (>21 days) distal biceps tendon repairs with a control cohort repaired acutely (<21 days). METHODS: Sixteen delayed repair cases were reviewed and matched with acute controls (1:3) based on repair technique, age, and workers' compensation status...
June 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28521693/from-tendon-injury-to-collagen-based-tendon-regeneration-overview-and-recent-advances
#4
Clément Rieu, Lise Picaut, Gervaise Mosser, Léa Trichet
Tendon injury is a clinical, societal and economical issue. Moreover, tendon repair represents an important clinical challenge, partly due to the mechanical constraints that occur at the junctions with muscle and bone. Several strategies have been developed for tendon repair. In this review, we first assess the importance of tendon injuries from different sites and their causes. After a short overview of tendon three-dimensional organization, the complexity of the perfect repair quest is presented ranging from current clinical procedures to new engineering scaffolds...
May 16, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28520458/anchored-transosseous-equivalent-versus-anchorless-transosseous-rotator-cuff-repair-a-biomechanical-analysis-in-a-cadaveric-model
#5
Kelly G Kilcoyne, Stanley G Guillaume, Catherine V Hannan, Evan R Langdale, Stephen M Belkoff, Uma Srikumaran
BACKGROUND: The original approach for the repair of torn rotator cuffs involved an open technique with sutures passing through the greater tuberosity and tendon. The development of suture anchors allowed for an all-arthroscopic approach with anchor configurations attempting to re-create a transosseous fixation pattern. Presently, an arthroscopic approach can be combined with a transosseous suture configuration without using anchors. PURPOSE: To evaluate cyclic loading, ultimate load to failure, and the failure mechanisms of transosseous-equivalent (TOE) repair with anchors and anchorless transosseous (AT) repair of rotator cuff tears...
May 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28514698/clinical-outcomes-and-frontal-plane-two-dimensional-biomechanics-during-the-30-second-single-leg-stance-test-in-patients-before-and-after-hip-abductor-tendon-reconstructive-surgery
#6
Rose E Huxtable, Timothy R Ackland, Gregory C Janes, Jay R Ebert
BACKGROUND: Hip abductor tendon tears are a common cause of Greater Trochanteric Pain Syndrome. Conservative treatments are often ineffective and surgical reconstruction may be recommended. This study investigated the improvement in clinical outcomes and frontal plane two-dimensional biomechanics during a 30-second single leg stance test, in patients undergoing reconstruction. We hypothesized that clinical scores and pertinent biomechanical variables would significantly improve post-surgery, and these outcomes would be significantly correlated...
May 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28509836/make-no-bones-about-it-rotator-cuff-repair-healing-is-not-just-about-the-tendon-commentary-on-an-article-by-shivam-a-shah-phd-et-al-sclerostin-antibody-treatment-enhances-rotator-cuff-tendon-to-bone-healing-in-an-animal-model
#7
https://www.readbyqxmd.com/read/28509826/sclerostin-antibody-treatment-enhances-rotator-cuff-tendon-to-bone-healing-in-an-animal-model
#8
Shivam A Shah, Ioannis Kormpakis, Necat Havlioglu, Michael S Ominsky, Leesa M Galatz, Stavros Thomopoulos
BACKGROUND: Rotator cuff tears are a common source of pain and disability, and poor healing after repair leads to high retear rates. Bone loss in the humeral head before and after repair has been associated with poor healing. The purpose of the current study was to mitigate bone loss near the repaired cuff and improve healing outcomes. METHODS: Sclerostin antibody (Scl-Ab) treatment, previously shown to increase bone formation and strength in the setting of osteoporosis, was used in the current study to address bone loss and enhance rotator cuff healing in an animal model...
May 17, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28507978/modified-tension-slide-technique-for-anatomical-distal-biceps-tenodesis-using-a-bicortical-endobutton-and-a-tenodesis-screw
#9
Jagadish Prabhu, Mohammed Khalid Faqi, Fahad Al-Khalifa, Rashad Khamis Awad
INTRODUCTION: Many surgical techniques have been described in the literature. In this article, we describe surgical technical details along with tips and tricks of distal biceps tendon tenodesis using the EndoButton and tension - slide technique, a modification of the suspensory cortical button technique, which allows the surgeon to tension and repairs the biceps tendon through the single longitudinal anterior incision. This modification in surgical technique of using dual implants, i...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28506489/enhancement-of-rotator-cuff-tendon-bone-healing-with-fibroblast-growth-factor-2-impregnated-in-gelatin-hydrogel-sheets-in-a-rabbit-model
#10
Takuya Tokunaga, Tatsuki Karasugi, Hitoshi Arimura, Ryuji Yonemitsu, Hidetoshi Sakamoto, Junji Ide, Hiroshi Mizuta
BACKGROUND: Application of fibroblast growth factor 2 (FGF-2) may improve the healing response after rotator cuff (RC) surgical repair. This study aimed to determine whether FGF-2-impregnated gelatin hydrogel sheet (GHS) incorporation into the bony trough on the greater tuberosity facilitates healing after RC surgical repair in rabbits. METHODS: We assigned 120 adult male Japanese white rabbits treated with unilateral surgery for supraspinatus tendon repair into the following groups: suture-only group (suture); suture and GHS with phosphate-buffered saline (carrier); suture and GHS with 3 µg of FGF-2 (F3); and suture and GHS with 30 µg of FGF-2 (F30)...
May 11, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28506172/the-effect-of-myostatin-gdf-8-on-proliferation-and-tenocyte-differentiation-of-rat-bone-marrow-derived-mesenchymal-stem-cells
#11
Wei Le, Jeffrey Yao
BACKGROUND: The future in flexor tendon surgery involves tissue engineering approaches directed toward increasing early repair strength to accelerate tendon healing and to allow for earlier onset of rehabilitation. Previous work has shown that pluripotential mesenchymal stem cells may be successfully delivered to a tendon repair site using a suture carrier. The current work describes the use of Myostatin (GDF-8) to help guide these delivered pluripotential stem cells to differentiate down a tenocyte lineage to potentially maximize the reparative effects of these cells at the tendon repair site...
June 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28506161/symmetric-peripheral-running-sutures-are-superior-to-asymmetric-peripheral-running-sutures-for-increasing-the-tendon-strength-in-flexor-tendon-repair
#12
N Takeuchi, T Okada, N Kozono, T Shimoto, H Higaki, Y Iwamoto
BACKGROUND: The fatigue strength of three peripheral suture techniques for flexor tendon repair was compared by cyclic loading of the repairs in the porcine flexor digitorum tendon. METHODS: Thirty-six tendons were sutured using only peripheral sutures with 6-0 Nylon. An initial cyclic load of 10 N for 500 cycles was applied and increased by 10 N for an additional 500 cycles at each new load until rupture. RESULTS: The fatigue strength of the symmetric running peripheral suture was 85...
June 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28502669/biomimetic-tendon-extracellular-matrix-composite-gradient-scaffold-enhances-ligament-to-bone-junction-reconstruction
#13
Huanhuan Liu, Long Yang, Erchen Zhang, Rui Zhang, Dandan Cai, Shouan Zhu, Jisheng Ran, Varitsara Bunpetch, Youzhi Cai, Boon Chin Heng, Yejun Hu, Xuesong Dai, Xiao Chen, Hongwei Ouyang
Management of ligament/tendon-to-bone-junction healing remains a formidable challenge in the field of orthopedic medicine to date, due to deficient vascularity and multi-tissue transitional structure of the junction. Numerous strategies have been employed to improve ligament-bone junction healing, including delivery of stem cells, bioactive factors, and synthetic materials, but these methods are often inadequate at recapitulating the complex structure-function relationships at native tissue interfaces. Here, we developed an easily-fabricated and effective biomimetic composite to promote the regeneration of ligament-bone junction by physically modifying the tendon extracellular matrix (ECM) into a Random-Aligned-Random composite using ultrasound treatment...
May 11, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28501463/home-based-rehabilitation-in-the-postoperative-treatment-of-flexor-tendon-repair
#14
M Sanmartín-Fernández, B Fernández-Bran, J Couceiro-Otero
OBJECTIVE: To evaluate the results and complications of flexor tendon repair in which a home-based rehabilitation program was utilized without the assistance of a hand therapist during the first 4postoperative weeks. MATERIAL Y METHODS: Between July 2009 and July 2014, a total of 21 digits in 15 patients were treated in our institution for complete laceration of the flexor tendons within the flexor pulley system (zone 1 and 2). Passive and active exercises performed by the patients themselves were started the morning after the operation...
May 10, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/28501341/chronic-boutonniere-deformity-cross-lateral-band-technique-using-palmaris-longus-autograft
#15
Serdar Duzgun, Alpay Duran, Ekrem Keskin, Ahmet K Yigit, Hasan Buyukdogan
PURPOSE: The purpose of this study was to evaluate the outcomes of treatment of chronic boutonniere deformity with a reconstruction technique using palmaris longus autograft. MATERIALS AND METHODS: Seven patients with chronic, posttraumatic, flexible boutonniere deformities referred to our clinic between January 2010 and September 2014 were included in the study. In all 7 patients, the lateral bands were deficient or damaged beyond repair. A novel reconstruction technique for chronic boutonniere deformity utilizing palmaris longus autograft was used...
May 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28501340/epitendinous-first-repair-of-zone-ii-flexor-digitorum-profundus-results-in-decreased-gliding-resistance
#16
Michael G Galvez, Garet C Comer, Arhana Chattopadhyay, Chao Long, Anthony W Behn, James Chang
PURPOSE: The importance of flexor tendon repair with both core and epitendinous suture placement has been well established. The objective of this study was to determine whether suture placement order affects gliding resistance and bunching in flexor digitorum profundus tendons in a human ex vivo model. METHODS: The flexor digitorum profundus tendons of the index, middle, ring, and little fingers of paired cadaver forearms were tested intact for excursion and mean gliding resistance in flexion and extension across the A2 pulley...
May 11, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28495756/cystic-fibrosis-transmembrane-conductance-regulator-mediates-tenogenic-differentiation-of-tendon-derived-stem-cells-and-tendon-repair-accelerating-tendon-injury-healing-by-intervening-in-its-downstream-signaling
#17
Yang Liu, Jia Xu, Liangliang Xu, Tianyi Wu, Yuxin Sun, Yuk-Wai Lee, Bin Wang, Hsiao-Chang Chan, Xiaohua Jiang, Jinfang Zhang, Gang Li
Tendons are a mechanosensitive tissue, which enables them to transmit to bone forces that are derived from muscle. Patients with tendon injuries, such as tendinopathy or tendon rupture, were often observed with matrix degeneration, and the healing of tendon injuries remains a challenge as a result of the limited understanding of tendon biology. Our study demonstrates that the stretch-mediated activation channel, cystic fibrosis transmembrane conductance regulator (CFTR), was up-regulated in tendon-derived stem cells (TDSCs) during tenogenic differentiation under mechanical stretching...
May 11, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28495576/quantitative-assessment-of-fatty-infiltration-and-muscle-volume-of-the-rotator-cuff-muscles-using-3-dimensional-2-point-dixon-magnetic-resonance-imaging
#18
Noboru Matsumura, Sota Oguro, Shigeo Okuda, Masahiro Jinzaki, Morio Matsumoto, Masaya Nakamura, Takeo Nagura
BACKGROUND: In patients with rotator cuff tears, muscle degeneration is known to be a predictor of irreparable tears and poor outcomes after surgical repair. Fatty infiltration and volume of the whole muscles constituting the rotator cuff were quantitatively assessed using 3-dimensional 2-point Dixon magnetic resonance imaging. METHODS: Ten shoulders with a partial-thickness tear, 10 shoulders with an isolated supraspinatus tear, and 10 shoulders with a massive tear involving supraspinatus and infraspinatus were compared with 10 control shoulders after matching age and sex...
May 8, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28488452/biomechanical-investigation-of-uneven-load-bearing-in-six-strand-lim-tsai-flexor-tendon-repair-using-fiberloop-%C3%A2
#19
R A S Hay, Y R Wong, A M Loke, S C Tay
We hypothesized that, in providing biomechanical strength, at least one of the two middle strands in a modified six-strand Lim-Tsai flexor tendon repair could be divided without obvious reduction in repair strength owing to uneven load bearing. A total of 40 porcine flexor digitorum profundus tendons were repaired using the six-strand Lim-Tsai technique with a 4-0 FiberLoop(®) suture and then divided into four equal groups. (no cut, one middle strand cut, both middle strand cut, one side strand cut). The biomechanical performance of repaired tendons was tested and found to vary according to the location of the cuts...
June 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/28486778/efficacy-of-thermoresponsive-photocrosslinkable-hydrogels-derived-from-decellularized-tendon-and-cartilage-extracellular-matrix-for-cartilage-tissue-engineering
#20
Benjamin B Rothrauff, Luca Coluccino, Riccardo Gottardi, Luca Ceseracciu, Silvia Scaglione, Luca Goldoni, Rocky S Tuan
Tissue engineering using adult mesenchymal stem cells (MSCs), a promising approach for cartilage repair, is highly dependent on the nature of the matrix scaffold. Thermoresponsive, photocrosslinkable hydrogels were fabricated by functionalizing pepsin-soluble decellularized tendon and cartilage extracellular matrices (ECM) with methacrylate groups. Methacrylated gelatin hydrogels served as controls. When seeded with human bone marrow mesenchymal stem cells (MSCs) and cultured in chondrogenic medium, methacrylated ECM hydrogels experienced less cell-mediated contraction, as compared against non-methacrylated ECM hydrogels...
May 9, 2017: Journal of Tissue Engineering and Regenerative Medicine
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