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https://www.readbyqxmd.com/read/28072475/safety-of-sulfur-hexafluoride-microbubbles-in-sonography-of-abdominal-and-superficial-organs-retrospective-analysis-of-30-222-cases
#1
Chunlin Tang, Kejing Fang, Yanli Guo, Rui Li, Xiaozhou Fan, Ping Chen, Zhaohui Chen, Qiangwei Liu, Ye Zou
OBJECTIVES: The purpose of this study was to investigate the safety of the sulfur hexafluoride microbubble contrast agent SonoVue (Bracco SpA, Milan, Italy) and to implement precautions with the intent of further improving the safety of this contrast agent. METHODS: A total of 30,222 patients undergoing contrast-enhanced sonography of abdominal and superficial organs in our hospital from January 2005 to December 2014 were retrospectively investigated. SonoVue was used as the ultrasound contrast agent...
January 10, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27998301/acute-polyarthritis-in-a-young-patient-caused-by-meningococcal-and-parvovirus-b19-infections-a-case-report-and-review-of-the-literature
#2
Virginie Lavoipierre, Anna Dellyes, Camille Aubry, Christine Zandotti, Pierre Lafforgue, Philippe Parola, Jean-Christophe Lagier
BACKGROUND: Meningococcal infection is a multifaceted disease including acute polyarthritis. This presentation should be known by clinicians in order to prevent delay in treatment. We report what we believe to be the first case of an association of parvovirus B19 and meningococcal polyarthritis in a young adult. CASE PRESENTATION: A 19-year-old Caucasian woman presented to our hospital with fever, intense leg pain, and a transient rash. A physical examination showed asymmetric polyarthritis and no neurological abnormalities...
December 20, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27995212/is-this-a-simple-drug-eruption-to-be-discharged
#3
Mucahit Emet, Ilker Akbas, Esra Senturk, Omer Faruk Elmas, Sahin Aslan
'Erythema Multiforme associated with Phenytoin And Cranial radiation Therapy' (EMPACT) is a very rare clinic situation and classified in EM-like drug reactions. It can be easily misdiagnosed as acute urticaria or drug eruption in ED. Initial symptoms may resemble a simple skin problem, but diagnosing and early hospitalization of the patients can be lifesaving. Here, we present a man with renal cell cancer and brain metastases who admitted to ED due to fever and generalized rash. His skin lesions beginning from his head and spreading through the torso appeared four days after the end of radiotherapy (11 days after the initial dose of both radiation and oral phenytoin)...
December 2016: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27993143/marginal-zone-lymphoma-derived-interfollicular-diffuse-large-b-cell-lymphoma-harboring-20q12-chromosomal-deletion-and-missense-mutation-of-birc3-gene-a-case-report
#4
Joseph Hatem, April M Schrank-Hacker, Christopher D Watt, Jennifer J D Morrissette, Adam I Rubin, Ellen J Kim, Sunita D Nasta, Mariusz A Wasik, Agata M Bogusz
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) typically leads to effacement of the nodal architecture by an infiltrate of malignant cells. Rarely (<1%), DLBCL can present with an interfollicular pattern (DLBCL-IF) preserving the lymphoid follicles. It has been postulated that DLBCL-IF is derived from marginal zone B cells and may represent a large-cell transformation of marginal zone lymphoma (MZL), however no direct evidence has been provided to date. Here we describe a rare case of a diagnostically challenging DLBCL-IF involving a lymph node in a patient with a prior history of lymphadenopathy for several years and MZL involving skin...
December 19, 2016: Diagnostic Pathology
https://www.readbyqxmd.com/read/27982356/vertical-transmission-of-dengue-infection-the-first-putative-case-reported-in-china
#5
Xueru Yin, Xiaozhu Zhong, Shilei Pan
Dengue is a systemic viral infection that is commonly transmitted between humans via mosquitoes. Other modes of transmission such as the vertical one are rare and have been infrequently reported in the literature. This report investigates one case of vertical transmission of dengue in Guangzhou, China. A G1P1 lady at 39 weeks of gestation was referred to the Huzhong Hospital presenting a fever for two days. She subsequently developed a skin rash on the back and lower limb and at that time she had already experienced five days of fever...
December 8, 2016: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/27939314/17-th-century-variola-virus-reveals-the-recent-history-of-smallpox
#6
Ana T Duggan, Maria F Perdomo, Dario Piombino-Mascali, Stephanie Marciniak, Debi Poinar, Matthew V Emery, Jan P Buchmann, Sebastian Duchêne, Rimantas Jankauskas, Margaret Humphreys, G Brian Golding, John Southon, Alison Devault, Jean-Marie Rouillard, Jason W Sahl, Olivier Dutour, Klaus Hedman, Antti Sajantila, Geoffrey L Smith, Edward C Holmes, Hendrik N Poinar
Smallpox holds a unique position in the history of medicine. It was the first disease for which a vaccine was developed and remains the only human disease eradicated by vaccination. Although there have been claims of smallpox in Egypt, India, and China dating back millennia [1-4], the timescale of emergence of the causative agent, variola virus (VARV), and how it evolved in the context of increasingly widespread immunization, have proven controversial [4-9]. In particular, some molecular-clock-based studies have suggested that key events in VARV evolution only occurred during the last two centuries [4-6] and hence in apparent conflict with anecdotal historical reports, although it is difficult to distinguish smallpox from other pustular rashes by description alone...
December 19, 2016: Current Biology: CB
https://www.readbyqxmd.com/read/27938598/-infantile-systemic-hyalinosis-a-case-report-and-literature-review
#7
J Lu, J Li, F Y Lin
Objective: To investigate the clinical, pathological and gene mutation features of infantile systemic hyalinosis(ISH). Method: Data of a child with ISH seen in Haikou Hospital were retrospectively analyzed for the diagnosis and differential diagnosis of infantile systemic hyalinosis and the relevant reports in literature were reviewed. Result: A 1 year and 1 month old boy showed limbs joint stiffness, limited mobility and double knee flexion at his first month of life. At third month, red rashes appeared on the body and gradually became purple, most of them were seen on the back and they were higher than the skin surface, uneven and did not fade when pressed...
December 2, 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27927236/chronic-infantile-neurological-cutaneous-and-articular-cinca-syndrome-a-review
#8
REVIEW
Martina Finetti, Alessia Omenetti, Silvia Federici, Roberta Caorsi, Marco Gattorno
INTRODUCTION: The Chronic Infantile Neurological Cutaneous and Articular (CINCA, or Neonatal-onset multisystem inflammatory disease NOMID) is a rare autoinflammatory disease identified in 1987 by Prieur et al., typically characterized by the triad of skin rash, arthropathy and central nervous system manifestations. It represents the most severe phenotype of the cryopyrin-associated periodic syndrome (CAPS). CLINICAL DESCRIPTION AND ETIOLOGY: The syndrome is due to autosomal dominant gain of function mutations in NLRP3, which encodes a key component of the innate immunity that regulates the activation and secretion of interleukin (IL)-1β...
December 7, 2016: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/27891350/hypersensitivity-with-inhalational-budesonide-an-under-recognised-entity
#9
Pramod Kumar Sharma, Neeraj Gupta, Najmul Hasan, Bhaskar Krishnamurthy, Surjit Singh
Hypersensitivity reactions are commonly encountered with drugs such as beta lactams, sulphonamides, allopurinol etc., Corticosteroids are frequently employed in the treatment of drug induced allergic reactions. Therefore, it is highly unlikely that a corticosteroid itself may cause such a reaction as an adverse effect. We had encountered a rare case of hypersensitivity reaction with inhalational budesonide in an eight-year-old boy. The patient developed maculopapular rashes over the back, buttocks and legs accompanied with pruritus within four hours of administration of the first dose...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27843372/wissler-fanconi-syndrome-and-related-diagnoses-a-case-report
#10
Mustafa Q Albustani, Robert F Howard
INTRODUCTION: Wissler-Fanconi syndrome is a rare rheumatic syndrome that was first described during the 1940s in Europe. Since then, many papers have been written that cover all aspects of this syndrome, most of which are in French and German language, with only a very few in English (none of them recent). We report here a case that fulfils the criteria for Wissler-Fanconi syndrome. Under the more general descriptive umbrella of Wissler-Fanconi syndrome, our patient also fulfils the Modified Jones criteria, and the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for rheumatoid arthritis, and was interpreted by other internists and another rheumatologist as fulfilling the Yamaguchi criteria for adult onset Still's disease...
2016: Open Access Rheumatol
https://www.readbyqxmd.com/read/27843213/pediatric-retrograde-intra-renal-surgery-for-renal-stones-2-cm-in-solitary-kidney
#11
Wael Mohamed Gamal, Mohamed M Hussein, El Nisr Rashed, Al-Dahshoury Mohamed, Ahmed Mmdouh, Farag Fawzy
INTRODUCTION: Management of renal stones in children with a solitary kidney is a challenge. In the current study, the efficacy and safety of retrograde intrarenal surgery (RIRS) in these children were determined. PATIENTS AND METHODS: Records of children with renal stones who were treated at our institute between August 2011 and August 2014 were retrospectively assessed. Inclusion criteria were: Children with single renal stone <2 cm size, in a solitary kidney...
October 2016: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/27826348/complete-heart-block-in-association-with-dengue-hemorrhagic-fever
#12
Hafeez Ul Hassan Virk, Faisal Inayat, Zia Ur Rahman
Dengue virus infection affects the heart structurally and functionally. Clinical manifestations of cardiac complications secondary to dengue virus infection vary from self-limiting arrhythmias to severe myocardial infarction, leading to hypotension, pulmonary edema, and cardiogenic shock. However, we report a case of dengue hemorrhagic fever (DHF) complicated by a complete heart block. A female with DHF due to dengue virus serotype 2, presented to the emergency department with fever, headache, rash, and fatigue followed by an episode of syncope...
November 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27752403/softball-petechiae-a-novel-cutaneous-finding-in-a-patient-participating-in-post-exercise-massage
#13
Talayesa Buntinx-Krieg, Jeffrey Greenwald
We report a case of a 39-year-old healthy male presenting with an eruption consisting of evenly spaced, well-circumscribed, round, petechial macules over a discrete region on his back. A detailed history revealed that the man participated in a high-intensity combination workout routine and post-exercise massage. He reported using a regulation-sized dimpled softball in order to massage the musculature of his back. A diagnosis of traumatic petechiae was established. A growing fitness culture encouraging high-intensity training and post-exercise massage coupled with the high costs of professional masseuse services has led to the increased use of self-massage techniques using both traditional and non-traditional massage equipment...
September 12, 2016: Curēus
https://www.readbyqxmd.com/read/27688147/bleomycin-induced-skin-toxicity-is-it-always-flagellate-erythema
#14
Shailendra Prasad Verma, Arunkumar Subbiah, Vinod Kolar Vishwanath, Tarun Kumar Dutta
Bleomycin-induced skin toxicity is a rare and unique complication. We report a 35-year-old man with nodular lymphocytic predominant Hodgkin's lymphoma, stage IVB, who was started on adriamycin, bleomycin, vinblastin and dacarbazine (ABVD) chemotherapy. He developed pruritic hyperpigmented, patchy skin lesions on the neck, back, chest and thighs after IA cycle of ABVD chemotherapy. Lesions were not typical flagellate rash but hyperpigmented, patchy and mildly pruritic lesions over the trunk and proximal extremities...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27680539/inflammatory-biomarkers-disease-activity-index-and-self-reported-disability-may-be-predictors-of-chronic-arthritis-after-chikungunya-infection-brief-report
#15
J Sepúlveda-Delgado, O L Vera-Lastra, K Trujillo-Murillo, L M Canseco-Ávila, R A Sánchez-González, O Gómez-Cruz, A Lugo-Trampe, I Fernández-Salas, R Danis-Lozano, A Contreras-Contreras, A Mendoza-Torres, S Domínguez-Arrevillaga, B A Mena-Vela, M Ocaña-Sibilla, J C Ramirez-Valdespino, L J Jara
The chikungunya virus (ChikV) is a reemerging mosquito-borne pathogen that causes disabling chronic arthritis. The relationship between clinical evolution and inflammatory biomarkers in patients with ChikV-induced arthritis has not been fully described. We performed a prospective case series to evaluate the association among joint involvement, self-reported disability, and inflammatory biomarkers. Patients with ChikV infection were followed for 1 year. Joint involvement and self-reported disability were evaluated with disease activity index 28 (DAS-28) and World Health Organization Disablement Assessment Schedule II (WHODAS-II)...
September 28, 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27609845/long-term-health-effects-of-the-eyjafjallaj%C3%A3-kull-volcanic-eruption-a-prospective-cohort-study-in-2010-and-2013
#16
Heidrun Hlodversdottir, Gudrun Petursdottir, Hanne Krage Carlsen, Thorarinn Gislason, Arna Hauksdottir
OBJECTIVES: To examine the long-term development of physical and mental health following exposure to a volcanic eruption. DESIGN: Population-based prospective cohort study. SETTING: In spring 2010, the Icelandic volcano Eyjafjallajökull erupted. Data were collected at 2 time points: in 2010 and 2013. PARTICIPANTS: Adult residents in areas close to the Eyjafjallajökull volcano (N=1096), divided according to exposure levels, and a non-exposed sample (n=475), with 80% participation rate in 2013...
2016: BMJ Open
https://www.readbyqxmd.com/read/27442327/suspected-female-to-male-sexual-transmission-of-zika-virus-new-york-city-2016
#17
Alexander Davidson, Sally Slavinski, Kendra Komoto, Jennifer Rakeman, Don Weiss
A routine investigation by the New York City (NYC) Department of Health and Mental Hygiene (DOHMH) identified a nonpregnant woman in her twenties who reported she had engaged in a single event of condomless vaginal intercourse with a male partner the day she returned to NYC (day 0) from travel to an area with ongoing Zika virus transmission. She had headache and abdominal cramping while in the airport awaiting return to NYC. The following day (day 1) she developed fever, fatigue, a maculopapular rash, myalgia, arthralgia, back pain, swelling of the extremities, and numbness and tingling in her hands and feet...
July 22, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27406461/disseminated-gonococcal-infection-an-unusual-presentation
#18
Saroj Lohani, Salik Nazir, Niranjan Tachamo, Nitin Patel
Gonococcus typically affects the mucosal surfaces but in rare cases can spread to bloodstream causing disseminated gonococcal infection (DGI). The usual presentation of DGI is rash, polyarthralgia, and tenosynovitis. We present the case of a 23-year-old female who presented to our hospital with pustular rash and tenosynovitis of hand and was sent home on Augmentin. Her symptoms worsened despite treatment and she presented back to the ED. On investigation, she was found to have DGI and was appropriately treated...
2016: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/27402586/dermatomyositis-as-a-paraneoplastic-phenomenon-in-ovarian-cancer
#19
Ilyas Arshad, Desmond Barton
A 60-year-old woman diagnosed with papillary serous ovarian cancer had Klean-Prep and MRI contrast preoperatively. Afterwards, she developed swelling and an urticarial rash around her eye as she proceeded to have planned debulking surgery. Postoperatively the swelling and rash had spread over her face, neck, back and chest. Dermatology advised a possible allergy to Klean-Prep and MRI contrast. Subsequently over the next few months, the patient became severely debilitated from proximal myopathy of the upper and lower limbs, suffered severe pain restricting mobility and small bowel obstruction...
July 8, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27308084/lumbar-swelling-as-the-unusual-presentation-of-henoch-schonlein-purpura-in-a-child
#20
Mehmet Ali Duman, Nilgün Selçuk Duru, Bahar Çalışkan, Hale Sandıkçı, Ferhat Çengel
BACKGROUND: Henoch-Schönlein Purpura (HSP) is a systemic hypersensitivity disease of unknown cause that is characterized by a purpuric rash and systemic manifestations, such as colicky abdominal pain, polyarthralgia, and acute glomerulonephritis. Common complications of HSP that lead to surgical intervention include intussusception, perforation, necrosis, and massive gastrointestinal bleeding. Unusual clinical manifestations of HSP may include edema of the scrotum and eyes. Lumbar swelling is rarely seen as a complication of HSP...
May 2016: Balkan Medical Journal
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