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https://www.readbyqxmd.com/read/29070622/sepsis-ptosis-an-unusual-diagnosis
#1
Brooke Leigh Powell, Oliver Toby Charles Morgan
The authors present the case of a 19-year old man presenting to the emergency department with a 2-day history of left eye pain and ptosis, facial pain around the maxillae, coryza, headaches and fevers. He had a background of autism, mild learning disability, obsessive-compulsive disorder and asthma. Within the last month, his risperidone and sertraline doses had been increased. Basic observations and investigations suggested sepsis: tachypnoea, sinus tachycardia, fever and a raised white cell count and C reactive protein level...
October 25, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29054953/vancomycin-associated-drug-reaction-with-eosinophilia-and-systemic-symptoms-dress-syndrome-masquerading-under-the-guise-of-sepsis
#2
Luke Maxfield, Toni Schlick, Angela Macri, James Thatcher
A patient presented with what appeared to be severe urosepsis. After admission and antibiotic administration, a newly developed rash and subsequent facial swelling appeared to be a reaction to penicillin class antibiotics. However, despite changing class of therapy with continued antimicrobial coverage, end organ damage continued, the rash worsened and facial oedema developed. Drug reaction with eosinophilia and systemic symptoms was ultimately diagnosed and was consistent with clinical and histopathological findings, as well as meeting all criteria for scoring systems...
October 19, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28978604/oxaliplatin-induced-posterior-reversible-encephalopathy-syndrome-pres
#3
Taimoor Khalid Janjua, Muhammad Hassan, Hira Khan Afridi, Naila Anjum Zahid
Posterior reversible encephalopathy syndrome (PRES), first introduced in 1996, is a neurotoxic state characterised by seizures, headache, vision change, paresis, nausea and altered mental status. Risk factors include hypertension, eclampsia/pre-eclampsia, infection/sepsis and cancer chemotherapy. Although exposure to toxic agents is a common occurrence in patients who develop PRES, oxaliplatin has rarely been associated with it, with only 10 cases reported worldwide. We present the case of an oxaliplatin-induced PRES in a 23-year-old male patient who was started on oxaliplatin/capecitabine as adjuvant chemotherapy for anal canal adenocarcinoma...
October 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28459729/trends-and-outcomes-of-early-versus-late-percutaneous-endoscopic-gastrostomy-placement-in-patients-with-traumatic-brain-injury-nationwide-population-based-study
#4
Rabail Chaudhry, Naveen Kukreja, Alex Tse, Greesha Pednekar, Anas Mouchli, Linda Young, Oksana Didyuk, Robert C Wegner, Navneet Grewal, George W Williams
BACKGROUND: Oral intake for traumatic brain injury (TBI) patients is often not an option because of facial trauma, swallowing dysfunctions, altered consciousness, etc. These patients often require percutaneous endoscopic gastrostomy (PEG) placement for nutrition support. To date, there is lack of studies examining the relationship between the timing of PEG placement and patient outcome in the TBI group. METHODS: We conducted a population-based study in a retrospective cohort of TBI patients undergoing PEG, using the national inpatient sample for years 2011 to 2013...
April 28, 2017: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/28405168/the-black-evil-affecting-patients-with-diabetes-a-case-of-rhino-orbito-cerebral-mucormycosis-causing-garcin-syndrome
#5
Santhosh Narayanan, Geetha Panarkandy, Gomathy Subramaniam, Chandni Radhakrishnan, N K Thulaseedharan, Neeraj Manikath, Sreejith Ramaswamy, Suma Radhakrishnan, Danish Ekkalayil
Mucormycosis is a life-threatening infection affecting patients with diabetes. It is an angioinvasive disease often resistant to treatment with a debilitating course and high mortality. Here, we report a case of a 45 year old woman with type 2 diabetes mellitus who presented to us with history of right-sided ptosis and facial palsy, and subsequently developed loss of vision and palatal palsy. She was in diabetic ketoacidosis. Nervous system examination revealed involvement of right second, third, fourth, sixth, seventh, ninth, and tenth cranial nerves, suggestive of Garcin syndrome...
2017: Infection and Drug Resistance
https://www.readbyqxmd.com/read/28262381/pediatric-sepsis-secondary-to-an-occult-dental-abscess-a%C3%A2-case-report
#6
Peter Holmberg, Thomas Hellmich, James Homme
BACKGROUND: In general, hematogenous spread of bacteria in children is uncommon. Bacteremia, however, is a known complication of dental procedures and severe caries, but is infrequently associated with primary, asymptomatic, non-procedural-related, dentoalveolar infection. CASE REPORT: The patient is a 7-year-old previously healthy boy who presented to the Emergency Department (ED) with "fever, mottling, and shaking chills." In the ED, he appeared systemically ill with fever, mottling, delayed capillary refill, and rigors...
May 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28242238/the-burden-of-facial-cellulitis-leading-to-inpatient-hospitalization
#7
Shelly Abramowicz, Sankeerth Rampa, Veerasathpurush Allareddy, Min Kyeong Lee
PURPOSE: The purpose of the present study was to present nationally representative estimates of hospitalizations primarily attributed to facial cellulitis and to conduct an exploratory analysis on identifying factors associated with outcomes, such as hospital charges, length of stay (LOS), disposition status, and occurrence of infectious complications. MATERIALS AND METHODS: The present study is a retrospective analysis of the Nationwide Inpatient Sample (NIS) for 2012 and 2013...
August 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27669150/shorter-duration-of-post-operative-antibiotics-for-cecal-ligation-and-puncture-does-not-increase-inflammation-or-mortality
#8
Kendra N Iskander, Max Vaickus, Elizabeth R Duffy, Daniel G Remick
Antimicrobial therapy for sepsis has beneficial effects, but prolonged use fosters emergence of resistant microorganisms, increases cost, and secondary infections. We tested whether 3 days versus 5 days of antibiotics in the murine model of cecal ligation and puncture (CLP) negatively influences outcomes. Following CLP mice were randomized to receive the antibiotic imipenem-cilastatin (25mg/kg) in dextrose 5% in Lactated Ringer's solution every 12 hours for either three or five days. Serial monitoring over 28 days included body weight, temperature, pulse oximetry, and facial vein sampling for hematological analysis and glucose...
2016: PloS One
https://www.readbyqxmd.com/read/27583356/sepsis-complicated-by-brain-abscess-following-eswl-of-a-caliceal-kidney-stone-a-case-report
#9
Alessandro Capitanini, Luca Rosso, Laura Giannecchini, Ophelia Meniconi, Adamasco Cupisti
A 47-year old, Caucasian man underwent extracorporeal shock wave lithotripsy (ESWL) of a 14mm calcium stone in the right renal pelvis, without urinary tract obstruction or sepsis. 24 hours after ESWL septic shock occurred and the patient was admitted to the Intensive Care Unit (ICU). Escherichia coli emerged from the blood and urine culture. The patient developed acute renal failure and it was necessary to start a continuous renal replacement therapy (CRRT). Infection was successfully treated, patient recovered renal function and an improvement of general condition occurred...
September 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27547476/reversal-of-dabigatran-using-idarucizumab-in-a-septic-patient-with-impaired-kidney-function-in-real-life-practice
#10
Thomas C Sauter, Sina Blum, Michael Nagler, Fabian L Schlittler, Meret E Ricklin, Aristomenis K Exadaktylos
Background. Immediate reversal of anticoagulation is essential when facing severe bleeding or emergency surgery. Although idarucizumab is approved for the reversal of dabigatran in many countries, clinical experiences are lacking, particularly in special patient-populations such as sepsis and impaired renal function. Case Presentation. We present the case of a 67-year-old male septic patient with a multilocular facial abscess and chronic kidney disease (GFR 36.5 mL/min). Thrombin time (TT) and activated partial thromboplastin time (aPTT) 15 hours after the last intake of 150 mg dabigatran were both prolonged (>120 sec, resp...
2016: Case Reports in Emergency Medicine
https://www.readbyqxmd.com/read/27392601/carotid-artery-dissection-and-motor-vehicle-trauma-patient-demographics-associated-injuries-and-impact-of-treatment-on-cost-and-length-of-stay
#11
Jared E Kray, Viktor Y Dombrovskiy, Todd R Vogel
BACKGROUND: Blunt carotid arterial injury (BCI) is a rare injury associated with motor vehicle collision (MVC). There are few population based analyses evaluating carotid injury associated with blunt trauma and their associated injuries as well as outcomes. METHODS: The Nationwide Inpatient Sample (NIS) 2003-2010 data was queried to identify patients after MVC who had documented BCI during their hospitalizations utilizing ICD-9-CM codes. Demographics, associated injuries, interventions performed, length of stay, and cost were evaluated...
2016: BMC Emergency Medicine
https://www.readbyqxmd.com/read/27344298/is-procalcitonin-a-useful%C3%A2-biomarker-for-the-risk-stratification-of-facial-cellulitis
#12
Chloé Bertolus, Thomas Schouman, Adeline Aubry, Pierre Hausfater
BACKGROUND: Facial cellulitis is an infectious disease that may require emergency surgical drainage based on clinical assessment. To date, no biological marker has been reported to be useful for risk stratification. Procalcitonin (PCT) is a diagnostic and prognostic sepsis biomarker. We aimed to study the usefulness of PCT dosage for the risk-stratification of facial cellulitis. PATIENTS AND METHODS: This was a monocentric prospective study conducted in a referral center for maxillofacial emergencies...
August 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27056621/autologous-adipose-derived-stem-cells-basic-science-technique-and-rationale-for-application-in-ulcer-and-wound-healing
#13
REVIEW
Ilaria Zollino, Michele Zuolo, Sergio Gianesini, Massimo Pedriali, Maria Grazia Sibilla, Mirko Tessari, Francesco Carinci, Savino Occhionorelli, Paolo Zamboni
Objectives The present review represents a translational boundary between basic research and surgery, particularly focusing on the promising application of adipose-derived stem cells harvested intra-operatively during debridement of venous leg ulcers. Methods We reviewed 830 out of 5578 articles on MEDLINE starting from 1997 and sorted by the relevance option. Results The technique currently used for adipose-derived stem cells intra-operative harvesting is presented, including a safety evaluation on a cohort of 5089 revised patients who underwent plastic surgery and maxillo-facial surgical procedures...
April 2017: Phlebology
https://www.readbyqxmd.com/read/26945392/identifying-mutations-of-the-tetratricopeptide-repeat-domain-37-ttc37-gene-in-infants-with-intractable-diarrhea-and-a-comparison-of-asian-and-non-asian-phenotype-and-genotype-a-global-case-report-study-of-a-well-defined-syndrome-with-immunodeficiency
#14
COMPARATIVE STUDY
Wen-I Lee, Jing-Long Huang, Chien-Chang Chen, Ju-Li Lin, Ren-Chin Wu, Tang-Her Jaing, Liang-Shiou Ou
Syndromic diarrhea/tricho-hepato-enteric syndrome (SD/THE) is a rare, autosomal recessive and severe bowel disorder mainly caused by mutations in the tetratricopeptide repeat domain 37 (TTC37) gene which act as heterotetrameric cofactors to enhance aberrant mRNAs decay. The phenotype and immune profiles of SD/THE overlap those of primary immunodeficiency diseases (PIDs). Neonates with intractable diarrhea underwent immunologic assessments including immunoglobulin levels, lymphocyte subsets, lymphocyte proliferation, superoxide production, and IL-10 signaling function...
March 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26546662/cutaneous-sinus-tracts-of-odontogenic-origin-two-case-reports
#15
Rosa Giménez-García, Fernando Martinez-Vera, Leticia Fuentes-Vera
BACKGROUND: Cutaneous odontogenic fistulas or sinus tracts are frequently misdiagnosed and incorrectly treated, leading to unnecessary procedures and patient suffering. An understanding of the draining of cutaneous sinus tracts will lead to more appropriate treatment. Most cases respond to conservative, nonsurgical root canal therapy. Our objective is to report 2 cases of cutaneous sinus tract secondary to chronic periapical dental infection that were recently observed at our hospital...
November 2015: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/26377576/root-sepsis-associated-with-insect-dwelling-sebaldella-termitidis-in-a-lesser-dwarf-lemur-cheirogaleus-medius
#16
Tobias Eisenberg, Stefanie P Glaeser, Peter Kämpfer, Nicole Schauerte, Christina Geiger
Sebaldella termitidis is a rare fastidious microorganism of the Leptotrichiaceae family. A variety of closely related species are associated with severe and even life-threatening disease in humans and animals, such as Streptobacillus moniliformis, the etiological organism of rat-bite fever as well as members of Leptotrichia spp. and Sneathia sanguinegens, which have been reported from cases of septicaemia. In contrast, since its description some 50 years ago, S. ermitidis has so far never been reported as a vertebrate pathogen, nor has it been found aside from its natural termite host...
December 2015: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/26250834/effects-of-noninvasive-positive-pressure-ventilation-with-different-interfaces-in-patients-with-hypoxemia-after-surgery-for-stanford-type-a-aortic-dissection
#17
RANDOMIZED CONTROLLED TRIAL
Yi Yang, Lizhong Sun, Nan Liu, Xiaotong Hou, Hong Wang, Ming Jia
BACKGROUND: Hypoxemia is a severe perioperative complication that can substantially increase intensive care unit and hospital stay and mortality. The aim of this study was to determine the effects of non-invasive positive-pressure ventilation (NIPPV) in patients with hypoxemia after surgery for Stanford type A aortic dissection, and to compare the effects of helmet and mask NIPPV. MATERIAL AND METHODS: We recruited 40 patients who developed hypoxemia within 24 h after extubation after surgery for Stanford type A aortic dissection in the Beijing Anzhen Hospital...
August 7, 2015: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/26242743/clinical-review-intensive-care-unit-acquired-weakness
#18
REVIEW
Greet Hermans, Greet Van den Berghe
A substantial number of patients admitted to the ICU because of an acute illness, complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle weakness during the ICU stay that is referred to as "intensive care unit acquired weakness" (ICUAW). This ICUAW evoked by critical illness can be due to axonal neuropathy, primary myopathy, or both. Underlying pathophysiological mechanisms comprise microvascular, electrical, metabolic, and bioenergetic alterations, interacting in a complex way and culminating in loss of muscle strength and/or muscle atrophy...
August 5, 2015: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/25947410/a-systemic-review-of-autologous-fat-grafting-survival-rate-and-related-severe-complications
#19
REVIEW
Nan-Ze Yu, Jiu-Zuo Huang, Hao Zhang, Yang Wang, Xiao-Jun Wang, Ru Zhao, Ming Bai, Xiao Long
OBJECTIVE: Clinical application of autologous fat grafting (AFG) is quickly expanding. Despite the widely acceptance, long-term survival rate (SR) of AFG remains a question not yet solved. Meanwhile, although rare, severe complications related to AFG including vision loss, stroke even death could be seen in the literature. DATA SOURCES: A comprehensive research of PubMed database to June 2013 was performed according to guidelines of the American Society of Plastic Surgeons Fat Graft Task Force Assessment Methodology...
May 5, 2015: Chinese Medical Journal
https://www.readbyqxmd.com/read/25241829/death-in-pediatric-cushing-syndrome-is-uncommon-but-still-occurs
#20
Alexandra Gkourogianni, Maya B Lodish, Mihail Zilbermint, Charalampos Lyssikatos, Elena Belyavskaya, Margaret F Keil, Constantine A Stratakis
UNLABELLED: Cushing syndrome (CS) in children is rare. Delayed diagnosis and treatment of CS may be associated with increased morbidity and, unfortunately, mortality. We performed a retrospective review of all patients with CS under the age of 18 years referred to the National Institutes of Health (NIH) from 1998 to 2013 in order to describe deceased patients among cases of pediatric CS referred to the National Institutes of Health (NIH). The deaths of four children (three females and one male), aged 7...
April 2015: European Journal of Pediatrics
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