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facial sepsis

Kendra N Iskander, Max Vaickus, Elizabeth R Duffy, Daniel G Remick
Antimicrobial therapy for sepsis has beneficial effects, but prolonged use fosters emergence of resistant microorganisms, increases cost, and secondary infections. We tested whether 3 days versus 5 days of antibiotics in the murine model of cecal ligation and puncture (CLP) negatively influences outcomes. Following CLP mice were randomized to receive the antibiotic imipenem-cilastatin (25mg/kg) in dextrose 5% in Lactated Ringer's solution every 12 hours for either three or five days. Serial monitoring over 28 days included body weight, temperature, pulse oximetry, and facial vein sampling for hematological analysis and glucose...
2016: PloS One
Alessandro Capitanini, Luca Rosso, Laura Giannecchini, Ophelia Meniconi, Adamasco Cupisti
A 47-year old, Caucasian man underwent extracorporeal shock wave lithotripsy (ESWL) of a 14mm calcium stone in the right renal pelvis, without urinary tract obstruction or sepsis. 24 hours after ESWL septic shock occurred and the patient was admitted to the Intensive Care Unit (ICU). Escherichia coli emerged from the blood and urine culture. The patient developed acute renal failure and it was necessary to start a continuous renal replacement therapy (CRRT). Infection was successfully treated, patient recovered renal function and an improvement of general condition occurred...
September 1, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Thomas C Sauter, Sina Blum, Michael Nagler, Fabian L Schlittler, Meret E Ricklin, Aristomenis K Exadaktylos
Background. Immediate reversal of anticoagulation is essential when facing severe bleeding or emergency surgery. Although idarucizumab is approved for the reversal of dabigatran in many countries, clinical experiences are lacking, particularly in special patient-populations such as sepsis and impaired renal function. Case Presentation. We present the case of a 67-year-old male septic patient with a multilocular facial abscess and chronic kidney disease (GFR 36.5 mL/min). Thrombin time (TT) and activated partial thromboplastin time (aPTT) 15 hours after the last intake of 150 mg dabigatran were both prolonged (>120 sec, resp...
2016: Case Reports in Emergency Medicine
Jared E Kray, Viktor Y Dombrovskiy, Todd R Vogel
BACKGROUND: Blunt carotid arterial injury (BCI) is a rare injury associated with motor vehicle collision (MVC). There are few population based analyses evaluating carotid injury associated with blunt trauma and their associated injuries as well as outcomes. METHODS: The Nationwide Inpatient Sample (NIS) 2003-2010 data was queried to identify patients after MVC who had documented BCI during their hospitalizations utilizing ICD-9-CM codes. Demographics, associated injuries, interventions performed, length of stay, and cost were evaluated...
2016: BMC Emergency Medicine
Chloé Bertolus, Thomas Schouman, Adeline Aubry, Pierre Hausfater
BACKGROUND: Facial cellulitis is an infectious disease that may require emergency surgical drainage based on clinical assessment. To date, no biological marker has been reported to be useful for risk stratification. Procalcitonin (PCT) is a diagnostic and prognostic sepsis biomarker. We aimed to study the usefulness of PCT dosage for the risk-stratification of facial cellulitis. PATIENTS AND METHODS: This was a monocentric prospective study conducted in a referral center for maxillofacial emergencies...
August 2016: Journal of Cranio-maxillo-facial Surgery
Ilaria Zollino, Michele Zuolo, Sergio Gianesini, Massimo Pedriali, Maria Grazia Sibilla, Mirko Tessari, Francesco Carinci, Savino Occhionorelli, Paolo Zamboni
OBJECTIVES: The present review represents a translational boundary between basic research and surgery, particularly focusing on the promising application of adipose-derived stem cells harvested intra-operatively during debridement of venous leg ulcers. METHODS: We reviewed 830 out of 5578 articles on MEDLINE starting from 1997 and sorted by the relevance option. RESULTS: The technique currently used for adipose-derived stem cells intra-operative harvesting is presented, including a safety evaluation on a cohort of 5089 revised patients who underwent plastic surgery and maxillo-facial surgical procedures...
April 7, 2016: Phlebology
Wen-I Lee, Jing-Long Huang, Chien-Chang Chen, Ju-Li Lin, Ren-Chin Wu, Tang-Her Jaing, Liang-Shiou Ou
Syndromic diarrhea/tricho-hepato-enteric syndrome (SD/THE) is a rare, autosomal recessive and severe bowel disorder mainly caused by mutations in the tetratricopeptide repeat domain 37 (TTC37) gene which act as heterotetrameric cofactors to enhance aberrant mRNAs decay. The phenotype and immune profiles of SD/THE overlap those of primary immunodeficiency diseases (PIDs). Neonates with intractable diarrhea underwent immunologic assessments including immunoglobulin levels, lymphocyte subsets, lymphocyte proliferation, superoxide production, and IL-10 signaling function...
March 2016: Medicine (Baltimore)
Rosa Giménez-García, Fernando Martinez-Vera, Leticia Fuentes-Vera
BACKGROUND: Cutaneous odontogenic fistulas or sinus tracts are frequently misdiagnosed and incorrectly treated, leading to unnecessary procedures and patient suffering. An understanding of the draining of cutaneous sinus tracts will lead to more appropriate treatment. Most cases respond to conservative, nonsurgical root canal therapy. Our objective is to report 2 cases of cutaneous sinus tract secondary to chronic periapical dental infection that were recently observed at our hospital...
November 2015: Journal of the American Board of Family Medicine: JABFM
Tobias Eisenberg, Stefanie P Glaeser, Peter Kämpfer, Nicole Schauerte, Christina Geiger
Sebaldella termitidis is a rare fastidious microorganism of the Leptotrichiaceae family. A variety of closely related species are associated with severe and even life-threatening disease in humans and animals, such as Streptobacillus moniliformis, the etiological organism of rat-bite fever as well as members of Leptotrichia spp. and Sneathia sanguinegens, which have been reported from cases of septicaemia. In contrast, since its description some 50 years ago, S. ermitidis has so far never been reported as a vertebrate pathogen, nor has it been found aside from its natural termite host...
December 2015: Antonie Van Leeuwenhoek
Yi Yang, Lizhong Sun, Nan Liu, Xiaotong Hou, Hong Wang, Ming Jia
BACKGROUND: Hypoxemia is a severe perioperative complication that can substantially increase intensive care unit and hospital stay and mortality. The aim of this study was to determine the effects of non-invasive positive-pressure ventilation (NIPPV) in patients with hypoxemia after surgery for Stanford type A aortic dissection, and to compare the effects of helmet and mask NIPPV. MATERIAL AND METHODS: We recruited 40 patients who developed hypoxemia within 24 h after extubation after surgery for Stanford type A aortic dissection in the Beijing Anzhen Hospital...
2015: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Greet Hermans, Greet Van den Berghe
A substantial number of patients admitted to the ICU because of an acute illness, complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle weakness during the ICU stay that is referred to as "intensive care unit acquired weakness" (ICUAW). This ICUAW evoked by critical illness can be due to axonal neuropathy, primary myopathy, or both. Underlying pathophysiological mechanisms comprise microvascular, electrical, metabolic, and bioenergetic alterations, interacting in a complex way and culminating in loss of muscle strength and/or muscle atrophy...
2015: Critical Care: the Official Journal of the Critical Care Forum
Nan-Ze Yu, Jiu-Zuo Huang, Hao Zhang, Yang Wang, Xiao-Jun Wang, Ru Zhao, Ming Bai, Xiao Long
OBJECTIVE: Clinical application of autologous fat grafting (AFG) is quickly expanding. Despite the widely acceptance, long-term survival rate (SR) of AFG remains a question not yet solved. Meanwhile, although rare, severe complications related to AFG including vision loss, stroke even death could be seen in the literature. DATA SOURCES: A comprehensive research of PubMed database to June 2013 was performed according to guidelines of the American Society of Plastic Surgeons Fat Graft Task Force Assessment Methodology...
May 5, 2015: Chinese Medical Journal
Alexandra Gkourogianni, Maya B Lodish, Mihail Zilbermint, Charalampos Lyssikatos, Elena Belyavskaya, Margaret F Keil, Constantine A Stratakis
UNLABELLED: Cushing syndrome (CS) in children is rare. Delayed diagnosis and treatment of CS may be associated with increased morbidity and, unfortunately, mortality. We performed a retrospective review of all patients with CS under the age of 18 years referred to the National Institutes of Health (NIH) from 1998 to 2013 in order to describe deceased patients among cases of pediatric CS referred to the National Institutes of Health (NIH). The deaths of four children (three females and one male), aged 7...
April 2015: European Journal of Pediatrics
Juan Rodolfo Mella, Evan L Chiswick, Elizabeth King, Daniel G Remick
OBJECTIVE: Considerable breakthroughs in the field of sepsis have been made using animal models. Sepsis exhibits a wide array of derangements that may be evaluated in the blood, including the release of proinflammatory and anti-inflammatory cytokines. The Shock journal adheres to the ARRIVE guidelines regarding reporting in vivo results to allow reproducibility of data findings. It is generally assumed that blood cytokine concentrations collected from typical sampling sites will be similar, but there are no data validating that this is true...
October 2014: Shock
M Aleman, J E Madigan, D C Williams, T A Holliday
BACKGROUND: Reports of the use of brainstem auditory evoked response (BAER) as a diagnostic modality in foals have been limited. HYPOTHESIS/OBJECTIVES: To describe BAER findings and associated causes of hearing loss in foals. ANIMALS: Study group 18 foals (15 neonatal, 3 nonneonatal), control group (5 neonatal foals). METHODS: Retrospective. BAER records from the Clinical Neurophysiology Laboratory were reviewed from the years of 1982 to 2013...
July 2014: Journal of Veterinary Internal Medicine
Jasmin Ali, Hannah Walsh, Swathi Sanapala, Nadeem Syed
A previously well 11-month-old infant presented with lethargy, a blanching rash, vomiting and diarrhoea. She was diagnosed with suspected gastroenteritis and discharged. The patient deteriorated and re-presented 24 h later with lumbar puncture (LP) confirming Neisseria meningitidis. Following an initial good response to ceftriaxone, the patient then developed a blistering facial rash on day 3 for which topical aciclovir was started with no improvement. She subsequently developed fever and redeveloped a rising C reactive protein (CRP)...
2014: BMJ Case Reports
Federico Maria Gioacchini, Alessio Baccarani, Domenico Villari, Valentina Postacchini, Matteo Alicandri-Ciufelli
BACKGROUND: Ecthyma gangrenosum (EG) involving the external ear canal is an unusual presentation. OBJECTIVE: To describe a case of EG diagnosed in a 5-day-old female who was admitted to our institute with multiple soft-tissue lesions involving the right arm, forearm, back, and perineum and with a complete facial palsy associated with ipsilateral external otitis. RESULTS: The patient presented neonatal sepsis associated with significant leucopenia, thrombocytopenia and alteration of the coagulation profile...
May 2014: Journal of Cutaneous Medicine and Surgery
Michelle Blanco, Owais Khan, Katherine Stanley, Joseph R Hageman, Siri Atma W Greeley
A male patient was born small for gestational age (SGA) at 33 weeks with a birth weight of 1,663 grams (< 10th percentile) and length 43 cm (10th percentile) to a 38-year-old G5P4 mother by cesarean section due to non-reassuring fetal heart tones. Prior to delivery, his mother experienced decreased fetal movement and decelerations. At birth, he was initially well-appearing and vigorous, with Apgar scores of 7 and 8 at 1 and 5 minutes, respectively. The physical examination was unremarkable--no skin findings, no facial anomalies, good tone, and the anterior fontanelle was soft and flat...
March 2014: Pediatric Annals
C Behera, A Rani, M Pradhan, P C Dikshit
The present study is a retrospective analysis of 13 cases of deaths, which resulted from throwing of corrosives over the body. The cases were autopsied at the Department of Forensic Medicine, Maulana Azad Medical College & Associated Hospitals, Delhi, India, during a period of 13 years from July 1998 to June 2011. The cases represented approximately 0.1% of all autopsy cases during the same period. Data were analyzed with regard to the age, sex, place of occurrence, pattern of injury, survival period, and cause of death...
June 2014: American Journal of Forensic Medicine and Pathology
T Radha Bai Prabhu
OBJECTIVES: The aim of this study was to analyze the incidence, possible etiological factors, pathology, clinical manifestations, brain CT scan features, treatment, and prognosis of cerebrovascular complications occurring in pregnancy and puerperium. METHODOLOGY: This is a prospective analytical study conducted at the Govt. Hospital for women and children, Chennai, from January 2006 to February 2008. During the above period, 26 women were diagnosed with various cerebrovascular complications...
April 2013: Journal of Obstetrics and Gynaecology of India
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