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https://www.readbyqxmd.com/read/29100720/prognostic-factors-for-parotid-metastasis-of-cutaneous-squamous-cell-carcinoma-of-the-head-and-neck
#1
C Bobin, P Ingrand, B Dréno, E Rio, O Malard, F Espitalier
BACKGROUND: Cutaneous squamous cell carcinoma (CSCC) develops on the head in 80% of cases. Parotid metastasis (PM) is rare, but treatment, which associates surgery and radiation therapy, is heavy and prognosis poor. MATERIAL AND METHODS: All cases of parotidectomy for PM of CSCC of the head and neck between 2005 and 2015 were studied retrospectively. Epidemiologic, oncologic and therapeutic data were analyzed. Overall and specific survival were calculated following Kaplan-Meier...
October 31, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29089142/survival-in-patients-with-parotid-gland-carcinoma-results-of-a-multi-center-study
#2
Keigo Honda, Shinzo Tanaka, Shogo Shinohara, Ryo Asato, Hisanobu Tamaki, Toshiki Maetani, Ichiro Tateya, Morimasa Kitamura, Shinji Takebayashi, Kazuyuki Ichimaru, Yoshiharu Kitani, Yohei Kumabe, Tsuyoshi Kojima, Koji Ushiro, Masanobu Mizuta, Koichiro Yamada, Koichi Omori
BACKGROUND: Parotid gland carcinoma is a rare malignancy, comprising only 1-4% of head and neck carcinomas; therefore, it is difficult for a single institution to perform meaningful analysis on its clinical characteristics. The aim of this study was to update the clinical knowledge of this rare disease by a multi-center approach. METHODS: The study was conducted by the Kyoto University Hospital and Affiliated Facilities Head and Neck Clinical Oncology Group (Kyoto-HNOG)...
October 24, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29054795/topical-ala-pdt-as-alternative-therapeutic-option-in-treatment-recalcitrant-dermatosis-report-of-4-cases
#3
REVIEW
Calvina Theresia, Jie Zheng, Xiao-Ying Chen
BACKGROUND: Topical Photodynamic therapy (PDT) is widely acknowledged for its safety and effectiveness in treating oncologic skin diseases such as basal cell carcinoma, actinic keratosis and squamous cell carcinoma in situ. Despite its broad applications in dermatology, this method is a relatively new therapeutic option for treating inflammatory/infectious skin diseases. OBJECTIVES: To determine whether topical PDT is a safe and effective treatment option in treating treatment-recalcitrant dermatosis...
October 17, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28987229/controversies-in-oral-and-maxillofacial-oncology
#4
REVIEW
Kyle S Ettinger, Jacob G Yetzer
Imaging studies are essential components of tumor diagnosis, staging, assessing tumor response to neoadjuvant and adjuvant therapies, and postoperative surveillance on completion of definitive treatment. Treatment of early stage clinically node negative oral cavity squamous cell carcinoma is controversial. Approximately 3% of all head and neck tumors arise within the parotid gland and most often within the superficial lobe, lateral to the facial nerve; about 80% are benign and most are pleomorphic adenoma. In patients with dry eyes failing multiple other treatment modalities and facing ongoing pain and loss of vision, microvascular transplant of the submandibular gland is a viable option...
November 2017: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/28936292/evolution-of-oral-cancer-treatment-in-an-andalusian-population-sample-rehabilitation-with-prosthetic-obturation-and-removable-partial-prosthesis
#5
Rafael Flores-Ruiz, Lizette Castellanos-Cosano, María-Angeles Serrera-Figallo, Aida Gutiérrez-Corrales, Maribel Gonzalez-Martin, Jose-Luis Gutiérrez-Pérez, Daniel Torres-Lagares
BACKGROUND: Radical surgical resection as a treatment modality for oral cancer often leads to an extensive deficit in both the maxillary and mandibular levels, where the use of a palatal obturator prosthesis (POP) or removable partial denture (RPP). The aim of this study was to evaluate the treatment with POP and RPP in patients treated for oral cancer in the Unit of Prosthetic Rehabilitation of the University Hospital Virgen del Rocío in a period of 20 years. MATERIAL AND METHODS: Retrospective descriptive study during the years 1991 and 2011 analyzing oral cancer type, characteristics, treatment and follow-up...
August 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28925316/objective-assessment-of-technical-skills-in-otorhinolaryngology-head-and-neck-surgery-residents-a-systematic-review
#6
Érika Mercier, Ségolène Chagnon-Monarque, François Lavigne, Tareck Ayad
Objectives The primary goal is the indexation of validated methods used to assess surgical competency in otorhinolaryngology-head and neck surgery (ORL-HNS) residents. Secondary goals include assessment of the reliability and validity of these tools, as well as the documentation of specific procedures in ORL-HNS involved. Data Sources MEDBASE, OVID, Medline, CINAHL, and EBM, as well as the printed references, available through the Université de Montréal library. Review Methods The PRISMA method was used to review digital and printed databases...
September 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28916260/primary-facial-reanimation-in-head-and-neck-cancer
#7
REVIEW
Axel Sahovaler, David Yeh, John Yoo
Facial Paralysis (FP) profoundly impairs the life of individuals, both functionally and psychosocially. Surgical approaches to treat this condition are myriad, but the ultimate goal is to restore symmetry and movement. Ablative surgery for tumors of the head and neck region are amongst the most common etiologies causing FP and this group of patients represents unique challenges. Surgical defects may have multiple competing reconstructive requirements and addressing the FP must be considered in this context...
November 2017: Oral Oncology
https://www.readbyqxmd.com/read/28894662/acellular-dermal-matrix-treating-periocular-melanoma-in-a-patient-with-xeroderma-pigmentosa
#8
Kamlen Pillay, Saleigh Adams, Laura Vandermaesen, Donald Anthony Hudson
We report a 7-year-old girl with xeroderma pigmentosum (XP), who presented in our clinic with a large melanoma (35 × 50 × 20 mm, Breslow depth 18 mm) in the zygomatic-malar area. Palliative surgery was performed to maintain her residual vision and to reduce the pain caused by the compression of local structures. Because of the limited access of autologous skin grafts in pediatric patients with XP who are severely affected, we opted to use an acellular dermal matrix. There was 100% graft uptake, and the pain due to compression by the tumor was alleviated...
August 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28807253/interdisciplinary-reconstruction-of-oncological-resections-at-the-skull-base-scalp-and-facial-region
#9
REVIEW
P M Vogt, T R Mett, G F Broelsch, C Radtke, N-C Gellrich, J K Krauss, M Samii, R Ipaktchi
Extensive bone and soft tissue defects of the skull require unique plastic and reconstructive techniques to avoid and optimize aesthetic appearance following oncological resections. Procedures are ideally planned in an interdisciplinary board composed of neurosurgery, otorhinolaryngology, plastic and reconstructive surgery to facilitate reconstructive procedures of soft tissue and bone as early as possible in one approach. Large resections may require plastic surgery involvement from the beginning. Herein, we describe the function of a multidisciplinary approach to complex oncologic resections of the cranial base, scalp, and facial regions for neuro-oncologic patients...
September 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28798812/clinical-epidemiological-and-therapeutic-profile-of-patients-with-a-retinoblastoma-diagnosis-experience-in-the-costa-rica-national-children-s-hospital-oncology-unit-from-january-2009-to-december-2015
#10
Jennie Chen Lo, Carlos Rodríguez, Rigoberto Monestel, Arnoldo Zúñiga
INTRODUCTION: Retinoblastoma represents only 3% of paediatric cancers, but it is the most prevalent intraocular tumour in this population. It develops in the retina as a primitive neuroectodermal tumour that affects development during gestation. The tumour presents in two different forms depending on whether or not it expresses a genetic modification. For patients diagnosed at preschool age, 75% are unilateral non-hereditary cases. While enucleation is the preferred treatment for advanced stages of the tumour, other modalities, such as systemic and intraocular chemotherapy, radiotherapy and local treatments with thermotherapy, cryotherapy, and brachytherapy can be used to try to preserve the eye...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28720529/population-characteristics-and-progressive-disability-in-neurofibromatosis-type-2
#11
Kensho Iwatate, Takeshi Yokoo, Eriko Iwatate, Masahiro Ichikawa, Taku Sato, Masazumi Fujii, Jun Sakuma, Kiyoshi Saito
OBJECTIVE: To characterize the clinical features of patients with neurofibromatosis type 2 (NF2) and determine prognostic risk factors for progressive disabilities. METHODS: In this retrospective cohort study of the Japanese national NF2 registry between 2009 and 2013, clinical data (demographic, history, oncologic, and neurologic) of 807 patients with a diagnosis of NF2 were analyzed. The overall severity of neurologic disability was assessed using a comprehensive 25-point scoring system encompassing a wide variety of neurologic deficits...
October 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28699165/ultrasound-guided-core-needle-biopsy-in-salivary-glands-a-meta-analysis
#12
REVIEW
Hee Joon Kim, Jong Seung Kim
OBJECTIVES/HYPOTHESIS: Core needle biopsy is an effective diagnostic tool widely used in many oncological diagnostic approaches. It provides an adequate tissue sample for histological evaluation of architecture, which allows tumor grading and classification of malignant and benign tumors. This study aimed to provide an updated meta-analysis and systematic review of core needle biopsy in the salivary glands. STUDY DESIGN: A literature search using PubMed, Embase, and the Cochrane Library through December 2016...
July 12, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28665855/lower-eyelid-reconstruction-after-ablation-of-skin-malignancies-how-far-can-we-get-in-a-single-stage-procedure
#13
Yordan Petrov Yordanov, Aylin Shef
: Reconstruction of full-thickness lower eyelid defects tends to be a devastating procedure, especially when big amount of tissue has to be removed because of oncological reasons. The applied techniques are mostly difficult to execute and multistaged, often require extensive dissection, and result in scarring and facial disfigurement.The aim of the present study is to demonstrate the authors' experience in single-staged reconstructions of full-thickness defects of the lower eyelid with local tissue only. MATERIAL AND METHODS: A retrospective analysis was conducted identifying patients with postexcisional defects after skin cancer occurring in the lower eyelid, reconstructed in 1 stage...
June 29, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28644156/clinical-case-of-the-month-a-57-year-old-man-with-an-axillary-mass
#14
Palak Desai, Andrew Myers, Brian Boulmay, Fred A Lopez
A 57-year-old man presented to the surgical oncology clinic with a mildly tender mass under his right arm. Four years prior, the patient had a melanoma removed from his right shoulder along with an ipsilateral right axillary sentinel lymph sampling. Computed tomography (CT) scan was negative for metastatic disease at that time. The patient did not undergo completion axillary node dissection and was lost to follow-up. The patient was originally from Australia, did not tan but reported multiple sunburns before age 18...
May 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28636741/adenoid-cystic-carcinoma-of-the-head-and-neck-area-oncologic-treatment-and-plastic-reconstructive-options
#15
Johannes A Veit, Julia Thierauf, Thomas K Hoffmann, Jens Greve, Nicole Rotter, Patrick J Schuler, Marc O Scheithauer
Adenoid cystic carcinoma of the head and neck area is a rare malignant tumor with acceptable short-term but mediocre long-term prognosis. Radical tumor excision with clear resection margins, and sometimes resection of the facial nerve due to perineural growth, remains the fundamental therapy. We present 3 distinct clinical cases and discuss the current therapeutic options with special focus on plastic-reconstructive techniques. For reconstruction, the full armament of local and free flaps, as well as prosthetics, may be necessary...
June 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28611639/superior-vena-cava-syndrome-in-a-patient-with-small-cell-lung-cancer-a-case-report
#16
Christina Brzezniak, Bryan Oronsky, Corey A Carter, Bennett Thilagar, Scott Caroen, Karen Zeman
Superior vena cava (SVC) syndrome, a potential oncologic emergency, is closely associated with malignancy and right-sided lung cancer in particular. A case of SVC syndrome presenting with facial swelling, neck distension, and enlarged veins of the upper chest, which developed over a period of 5 weeks in a 46-year-old patient on a clinical trial with small-cell lung cancer, is reported. Computed tomography scan of the chest revealed slight enlargement of a superior conglomerate mediastinal lymphadenopathy and intramural thrombus of the SVC...
January 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28607957/analysis-of-patient-outcomes-following-proton-radiation-therapy-for-retinoblastoma
#17
Kent W Mouw, Beow Y Yeap, Paul Caruso, Aaron Fay, Madhusmita Misra, Roshan V Sethi, Shannon M MacDonald, Yen-Lin Chen, Nancy J Tarbell, Torunn I Yock, Suzanne K Freitag, John E Munzenrider, Eric Grabowski, Michelle Katz, Karen Kuhlthau, Dawn DeCastro, Gena Heidary, Jessica Ciralsky, Shizuo Mukai, Helen A Shih
PURPOSE: Proton radiotherapy (PRT) is used in the treatment of retinoblastoma (RB) and has the potential to minimize exposure of normal tissue to radiation and thus decrease risk of toxicity and second malignancies. However, comprehensive analyses of long-term patient outcomes are not available. METHODS: RB patients treated with PRT at our institution between 1986 and 2012 were invited to return for participation in a study designed to assess long-term outcomes...
January 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28597346/the-rate-of-facial-nerve-dysfunction-and-time-to-recovery-after-intraparotid-and-extraparotid-facial-nerve-exposure-and-protection-in-head-and-neck-cutaneous-tumor-surgery
#18
Yasuhiro Nakamura, Yukiko Teramoto, Yuri Asami, Taichi Imamura, Sayuri Sato, Ryota Tanaka, Hiroshi Maruyama, Yoshiyuki Nakamura, Yasuhiro Fujisawa, Manabu Fujimoto, Akifumi Yamamoto
BACKGROUND: Most patients with head and neck skin tumors present with normal facial nerve function. A common treatment strategy for these patients is facial nerve preservation surgery, although the degree to which the nerve is successfully preserved is still unclear. Data on the incidence and recovery of facial nerve dysfunction are woefully lacking in the field of dermato-oncology. METHODS: In 23 patients with normal preoperative facial nerve function, we retrospectively reviewed twenty-six head and neck surgical interventions that included facial nerve exposure and protection, focusing particularly on the differences in outcome between intraparotid and extraparotid exposure of the facial nerve branches...
June 9, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28582371/clinical-presentation-and-anatomical-location-of-orbital-plasmacytomas
#19
Bradley A Thuro, Oded Sagiv, Roman Shinder, J Matthew Debnam, Omar Ozgur, John D Ng, Daniel Rootman, Sheeba K Thomas, Bita Esmaeli
PURPOSE: To evaluate the clinical and anatomical location of orbital plasmacytomas and assess local control following therapy. METHODS: The American Society of Ophthalmic Plastic and Reconstructive Surgery Oncology Database was queried to identify patients diagnosed with orbital plasmacytoma. These patients' records were reviewed for demographic characteristics, clinical and radiologic findings, treatments, and outcomes. RESULTS: Thirty patients from 4 institutions (24 from MD Anderson Cancer Center, 3 from SUNY Downstate Medical Center, 2 from University of California, Los Angeles, and 1 from Oregon Health and Science University) were identified...
June 2, 2017: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28565774/effects-of-ankaferd-bloodstopper-on-bone-healing-in-an-ovariectomized-osteoporotic-rat-model
#20
Şeref Ezirganli, Hakki Oğuz Kazancioğlu, Ahmet Hüseyin Acar, Hakan Özdemir, Emre Kuzu, Deniz Şahin İnan
Bone defects resulting from oncological surgical resections, congenital facial anomalies, trauma or infection represent a significant and common clinical problem. The present study aimed to evaluate the effects of a commercially-available medicinal plant extract product, Ankaferd BloodStopper (ABS), on bone healing. The present study was performed on 24 female ovariectomized (OVX) rats. A defect on each rat calvarium was created using a trephine burr prior to the rats being divided into two groups. Defects were grafted with a gelatin sponge soaked with normal saline (control group) or plant extract (experimental group)...
May 2017: Experimental and Therapeutic Medicine
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