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https://www.readbyqxmd.com/read/28302316/defining-nervous-system-susceptibility-during-acute-and-latent-herpes-simplex-virus-1-infection
#1
REVIEW
Chandra M Menendez, Daniel J J Carr
Herpes simplex viruses are neurotropic human pathogens that infect and establish latency in peripheral sensory neurons of the host. Herpes Simplex Virus-1 (HSV-1) readily infects the facial mucosa that can result in the establishment of a latent infection in the sensory neurons of the trigeminal ganglia (TG). From latency, HSV-1 can reactivate and cause peripheral pathology following anterograde trafficking from sensory neurons. Under rare circumstances, HSV-1 can migrate into the central nervous system (CNS) and cause Herpes Simplex Encephalitis (HSE), a devastating disease of the CNS...
March 8, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28297814/-igg4-related-lung-disease-analysis-of-8-cases-and-literature-review
#2
G J Han, H Hu, D Mao, X Bai, D Y She, S F Zhao, Z L Wen, J Gao
Objective: To improve the understanding and treatment of IgG4-related lung disease (IgG4-RLD). Methods: The clinical characteristics, serum IgG4 levels, pathological features, chest CT, therapy and prognosis of 8 patients with IgG4-RLD were retrospectively analyzed. These patients were admitted to the People's Liberation Army General Hospital and the pathological diagnosis was made between December 2005 and March 2016. Relevant literatures were reviewed. Results: The 8 patients with IgG4-RLD included 4 men and 4 women, with an average age of (59±4) years (range, 37-74)...
March 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28296237/inpatient-treatment-of-patients-with-acute-idiopathic-peripheral-facial-palsy-a-population-based-healthcare-research-study
#3
Katharina Plumbaum, Gerd Fabian Volk, Daniel Boeger, Jens Buentzel, Dirk Esser, Andreas Steinbrecher, Katrin Hoffmann, Peter Jecker, Andreas Mueller, Gerald Radtke, Otto W Witte, Orlando Guntinas-Lichius
OBJECTIVES: To determine the inpatient management for patients with acute idiopathic facial palsy (IFP) in Thuringia, Germany. DESIGN: Population-based study. SETTING: All inpatients with IFP in all hospitals with departments of otolaryngology and neurology in 2012 in the German federal state Thuringia. MAIN OUTCOME MEASURES: Patients' characteristics and treatment were compared between departments, and the probability of recovery was tested...
March 10, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28294978/discriminative-features-in-three-autosomal-recessive-cutis-laxa-syndromes-cutis-laxa-iia-cutis-laxa-iib-and-geroderma-osteoplastica
#4
REVIEW
Ariana Kariminejad, Fariba Afroozan, Bita Bozorgmehr, Alireza Ghanadan, Susan Akbaroghli, Hamid Reza Khorram Khorshid, Faezeh Mojahedi, Aria Setoodeh, Abigail Loh, Yu Xuan Tan, Nathalie Escande-Beillard, Fransiska Malfait, Bruno Reversade, Thatjana Gardeitchik, Eva Morava
Cutis laxa is a heterogeneous condition characterized by redundant, sagging, inelastic, and wrinkled skin. The inherited forms of this disease are rare and can have autosomal dominant, autosomal recessive, or X-linked inheritance. Three of the autosomal recessive cutis laxa syndromes, namely cutis laxa IIA (ARCL2A), cutis laxa IIB (ARCL2B), and geroderma osteodysplastica (GO), have very similar clinical features, complicating accurate diagnosis. Individuals with these conditions often present with cutis laxa, progeroid features, and hyperextensible joints...
March 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28286393/versatility-of-fibula-free-flap-in-reconstruction-of-facial-defects-a-center-study
#5
Sunil S Shroff, Sanjiv C Nair, Anjan Shah, Balasubramanya Kumar
PURPOSE: To study a series of cases where vascularised fibula flap was used in various combinations of bone with muscle and skin along with its modifications for reconstruction of simple and composite defects of the facial region. PATIENTS AND METHODS: The investigators designed a retrospective study composed of patients with any pathology or defect who underwent reconstruction of maxilla or mandible with vascularised fibula free flap from 2009 to 2013. All patients were evaluated for age, gender, location and type of defect, incorporation of adjoining skin paddle and muscle, number of fibula osteotomies, ischaemia time, anticoagulant regimen, length of hospital stay, flap failure rate, dental implant rehabilitation...
March 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28280662/avoiding-facial-incisions-with-midface-free-tissue-transfer
#6
Mark W Stalder, Michael Sosin, Leo J Urbinelli, James L Mayo, Amir H Dorafshar, Hugo St Hilaire, Daniel E Borsuk, Eduardo D Rodriguez
BACKGROUND: We have adopted an intraoral microsurgical anastomosis to the facial vessels to eliminate the need for any visible facial incisions. METHODS: Cadaveric dissection was used to demonstrate accessibility of the facial artery and vein through an intraoral approach. Additionally, 5 patients underwent free tissue transfer for reconstruction of major defects of the midface through an intraoral, transmucosal approach, obviating the need for visible skin incisions...
February 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28279397/-reconstruction-of-the-ear-in-the-burns-patient
#7
Jorge Raúl Carrillo-Córdova, Yusef Jiménez Murat, Armando Apellaniz-Campo, Hazel Bracho-Olvera, Raúl Carrillo Esper
Face burns are a singular pathology with great functional and psychological impact in the patients suffering them. The ears play a fundamental role in personal interactions and damage to this organ results in physical and emotional distress. The reconstructive treatment of the burned ear is a challenge. Multiple procedures have been described to achieve success in the reconstruction of the burned ear; immediate reconstruction with autologous rib cartilage, secondary reconstruction, alloplastic material reconstruction, tissue expansion, skin grafts and also microvascular flaps are some of the most common procedures used in this patients...
March 6, 2017: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28271520/expanded-transcanal-transpromontorial-approach-to-the-internal-auditory-canal-pilot-clinical-experience
#8
Livio Presutti, Matteo Alicandri-Ciufelli, Marco Bonali, Alessia Rubini, Giacomo Pavesi, Alberto Feletti, Barbara Masotto, Lukas Anschuetz, Daniele Marchioni
OBJECTIVES/HYPOTHESIS: The aim of this study was to describe and evaluate the feasibility of an expanded transcanal transpromontorial approach, developed from the exclusive endoscopic transcanal transpromontorial approach. STUDY DESIGN: Retrospective case series. METHODS: Retrospective chart review of 10 patients operated by an expanded transcanal transpromontorial approach in two tertiary referral centers (University Hospital of Modena, Italy and University Hospital of Verona, Italy)...
March 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28267931/ct-sinus-and-facial-bones-reporting-by-radiographers-findings-of-an-accredited-postgraduate-programme
#9
Paul Lockwood
OBJECTIVES: The aim of this study was to compare the observer performance of a cohort of radiographer's in reporting Computed Tomography (CT) sinus and facial bones investigations against a reference standard and alternative comparator of summary data from peer reviewed literature. METHODS: The participants (n=6) completed a 9-month part-time distance learning training programme prior to reporting an examination bank (n=25 cases) from a retrospectively collected and anonymised DICOM archive of CT examinations with referral histories and clinical reports...
March 7, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28264555/the-effect-of-insulin-like-growth-factor-1-on-recovery-of-facial-nerve-crush-injury
#10
Asuman Feda Bayrak, Yuksel Olgun, Ayla Ozbakan, Safiye Aktas, Can Ahmet Kulan, Gonca Kamaci, Emine Demir, Osman Yilmaz, Levent Olgun
Objectives: The aim of this study is to investigate the efficacy of locally applied insulin-like growth factor 1 (IGF-1) on the recovery of facial nerve functions after crush injury in a rabbit model. Methods: The rabbits were randomly assigned into three groups. Group 1 consisted of the rabbits with crush injury alone; group 2, the animals applied saline solution onto the crushed facial nerve and group 3, IGF-1 implemented to the nerve in the same manner. Facial nerve injury was first electrophysiologically studied on 10th and 42nd days of the procedure...
March 8, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28264248/one-stage-posterior-minimal-laminectomy-and-video-assisted-thoracoscopic-surgery-vats-for-removal-of-thoracic-dumbbell-tumor
#11
Kyoung Hyup Nam, Hyo Yeoung Ahn, Jeong Su Cho, Yeoung Dae Kim, Byung Kwan Choi, In Ho Han
OBJECTIVE: This study was conducted to assess the surgical results of one-stage posterior minimal laminectomy and video-assisted thoracoscopic surgery (VATS) for the treatment of thoracic dumbbell tumor and to describe its precise technique. In addition, we investigated the technique's usefulness and limitations. METHODS: Seven cases of thoracic dumbbell tumor (two men and five women, mean age, 43 years) were analyzed retrospectively. Pathological findings included schwannoma in four patients, neurofibroma in two patients, and hemangioma in one patient...
March 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/28258662/a-novel-gja1-mutation-in-oculodentodigitaldysplasia-with-extensive-loss-of-enamel
#12
Thantrira Porntaveetus, Chalurmpon Srichomthong, Atsushi Ohazama, Kanya Suphapeetiporn, Vorasuk Shotelersuk
OBJECTIVE: To characterize clinical features and identify genetic causes of a patient with oculodentodigital dysplasia (ODDD) SUBJECTS AND METHODS: Clinical, dental, radiological features were obtained. DNA was collected from an affected Thai family. Whole Exome Sequencing (WES) was employed to identify the disease-causing mutation causing ODDD. The presence of the identified variant was confirmed by Sanger sequencing. RESULTS: The proband suffered with extensive enamel hypoplasia, polysyndactyly and clinodactyly of the 3(rd) -5(th) fingers, microphthalmia, and unique facial characteristics of ODDD...
March 4, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28239591/role-of-ct-mastoids-in-the-diagnosis-and-surgical-management-of-chronic-inflammatory-ear-diseases
#13
Juveria Majeed, L Sudarshan Reddy
Chronic Suppurative Otitis Media (CSOM) is a chronic inflammation of middle ear cleft. It presents with discharging ear and decreased hearing. The diagnosis is mostly on clinical examination with otoscope or oto endoscope. Computerised Tomography (CT) of mastoids is done to evaluate the extent of the disease and its complication. High resolution CT is now the investigation of choice for temporal bone disease. This study emphasizes on the importance of CT scan in diagnosis of inflammatory ear diseases and most importantly identifying pitfalls or complications which a surgeon can come across during surgery...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28225994/a-rare-case-of-ectopic-acth-syndrome-originating-from-malignant-renal-paraganglioma
#14
Esra Tutal, Demet Yılmazer, Taner Demirci, Evrim Cakır, Salih Sinan Gültekin, Bahadır Celep, Oya Topaloğlu, Erman Çakal
Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of a non-pituitary ACTH-secreting tumor leading to Cushing's syndrome. Only a few cases have been reported previously as causing ectopic ACTH related to paraganglioma. Herein, we present a case of Cushing's syndrome, in who was proved to be attributable to an ACTH-secreting renal malignant paraganglioma. A 40-year-old woman presented with a five-month history of newly diagnosed hypertension and diabetes, weakness, hyperpigmentation, oligomenorrhea, hirsutism, and acneiform lesions...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28218014/bilateral-otoneurological-pathology-to-operate-or-not
#15
Shivun Khosla, Matthew Elliot, Neil Donnelly
OBJECTIVE: To illustrate our experience when managing a complex patient with potentially life-threatening bilateral otological disease facing multisensory compromise including complete loss of audiovestibular function and visual disturbance Clinical presentation: A 67 year old lady, presented with a large left vestibular schwannoma and extensive right cholesteatoma encircling the otic capsule. She underwent translabyrinthine resection of the vestibular schwannoma, resulting in profound sensorineural hearing loss, vestibular hypofunction and corneal scarring following an initial temporary facial palsy...
March 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/28217437/spontaneous-pneumomediastinum-in-a-healthy-young-female-a-case-report-and-literature-review
#16
Ahmed Dirweesh, Chikezie Alvarez, Muhammad Khan, Donald Christmas
Spontaneous pneumomediastinum (SPM) is an uncommon finding in young adults presenting usually without any comorbidities or an underlying pathology. It is most commonly due to alveolar rupture in the setting of an inciting event such an underlying asthma, barotrauma, valsalva maneuver, or esophageal rupture. Individuals can have varying presentations, from chest pain, dyspnea and dysphagia, to anxiety, weakness, or facial and neck swelling. The majority of patients have subcutaneous emphysema on examination and can have abnormal laboratory findings such as an elevated C-reactive proteins and leukocytosis...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28213198/a-rare-presentation-of-an-enterogenous-cyst-as-an-intra-axial-pontine-lesion
#17
Tengfei Li, Xia Wu, Yuekang Zhang
A 56-year-old man was admitted to our hospital with intermittent right facial numbness for 1 year and instability on walking for 6 months. Magnetic resonance imaging revealed an ovoid and well-demarcated intra-axial pontine lesion. Cyst fenestration and biopsy were carried out, and the diagnosis of enterogenous cyst was made by magnetic resonance imaging and pathologic findings. Preoperative symptoms resolved completely 3 months after surgery and no evidence of recurrence was found during 3 years of follow-up...
February 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28212125/functional-endoscopic-surgery-after-facial-trauma
#18
Marzia Petrocelli, Carolina Sbordone, Giovanni Salzano, Francesco Maria Cassandro, Giuseppe Chiarella, Alfonso Scarpa, Antonio Romano, Giorgio Iaconetta, Luigi Califano, Ettore Cassandro
The present study describes 3 patients of previous facial trauma who have subsequently been treated with functional endoscopic sinus surgery. The authors want pay attention on the possible correlation between facial trauma and sinusitis. Such fractures can be the cause of onset of paranasal sinusitis or of worsening of a previous sinusitis. The correlation between these 2 pathologies could be due to the fact that facial fractures concern the anatomic structures of paranasal sinuses. The damage to these structures during the facial trauma and tissue regeneration after injury or surgical treatment subverts the anatomy and function of the sinuses in a basically compromised situation...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28210449/oral-mucosal-lesions-in-a-chilean-elderly-population-a-retrospective-study-with-a-systematic-review-from-thirteen-countries
#19
César Rivera, Daniel Droguett, María-Jesús Arenas-Márquez
BACKGROUND: The oral examination is an essential part of the multidisciplinary medical care in elderly people. Oral mucosal lesions and normal variations of oral anatomy (OMLs) are very common in this people, but few studies have examined the frequency and prevalence of these conditions worldwide and less in Chile. The aim of this research was to evaluate the frequency of OMLs in a Chilean elderly population. MATERIAL AND METHODS: It was conducted a retrospective study (Talca, Chile)...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28192274/activity-and-connectivity-of-the-cerebellum-in-trigeminal-nociception
#20
Jan Mehnert, Laura Schulte, Dagmar Timmann, Arne May
The role of the cerebellum in pathologies of the trigeminal nervous system is still unknown although recently gathered evidence point to a modulatory rather than a passive role. Here we provide evidence for the activation of specific cerebellar areas during nociceptive trigeminal input in the left nostril in a large number of volunteers (54 subjects) and an additional independent group (18 subjects) as measured by functional magnetic resonance imaging (fMRI). Peak voxel activity ipsilateral to the stimulated side can be seen in cerebellar lobules VI, VIIIa and Crus I, and vermal lobule VIIIa, although some activations are also seen in the contralateral side...
February 10, 2017: NeuroImage
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