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hypoglicemia treatment

Matteo Monami, Sara Aleffi
Diabetes mellitus is one of the most important causes of cardiovascular morbidity and mortality; the incidence of chronic complications of diabetes appears to be closely related to the degree of hyperglycaemia. However, results of clinical trials showed that intensive treatment of hyperglycaemia prevents microvascular complications, but has little or no effect on the incidence of cardiovascular events. Different hypoglycaemic drugs show different effects on cardiovascular risk. However, those trials have shown a neutral effect on cardiovascular mortality...
2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
José Sampaio-Neto, Alcides José Branco-Filho, Luis Sérgio Nassif, André Thá Nassif, Flávia David João De Masi, Daniele Rezende Ximenez
BACKGROUND: Hyperinsulinemic hypoglicemia with severe neuroglycopenic symptoms has been identified as a late and rare complication in patients submitted to Roux-en-Y gastric bypass. However, the potential gravity of its manifestations requires effective treatment of this condition. The absence of treatment makes it necessary to develop more effective clinical or surgical methods. AIM: To present one surgical option to revisional surgery in the treatment of hyperinsulinemic hypoglicemia Methods : The procedure consists in reconstituting alimentary transit through the duodenum and proximal jejunum, while keeping the restrictive part of the gastric bypass...
November 2015: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
Martín de Santibañes, Agustín Cristiano, Oscar Mazza, Luis Grossenbacher, Eduardo de Santibañes, Rodrigo Sánchez Clariá, Enrique Sivori, Ricardo García Mónaco, Juan Pekolj
BACKGROUND: The endogenous hyperinsulinemic hypoglicemia syndrome (EHHS) can be caused by an insulinoma, or less frequently, by nesidioblastosis in the pediatric population, also known as non insulinoma pancreatic hypoglycemic syndrome (NIPHS) in adults. The aim of this paper is to show the strategy for the surgical treatment of ehhs. MATERIAL AND METHODS: A total of 19 patients with a final diagnosis of insulinoma or NIPHS who were treated surgically from january 2007 until june 2012 were included...
October 2014: Cirugía Española
Liiljana Baloš, Silvija Sajić, Vera Zdravković
INTRODUCTION: Diabetes mellitus type 1 (T1DM) in children is characterized by unstable course. A significant number of studies shows that introduction to insulin analogues treatment aims towards better control of the disease. OBJECTIVE: The assessment of metabolic control in children with T1DM that were introduced to insulin analogue treatment after many years of treatment with classic (human) insulin. METHODS: The study included 59 patients 2-19 years old (12...
September 2011: Srpski Arhiv za Celokupno Lekarstvo
Alia Ramírez-Camacho, Silvia Meavilla, Natalia Catalán, Alejandra Gutiérrez, Jaume Campistol
INTRODUCTION: Epilepsy is a disease where most patients have a good control with pharmacological antiepileptic treatment. Nevertheless, 25% of the patients have a refractory epilepsy to usual antiepileptic drugs. Ketogenic diet is one of the treatment options for this type of epilepsy. In spite of the increased popularity of it as an antiepileptic treatment, it does not exist an international consensus of its indications and management. AIM: To evaluate the response, tolerance and adverse effects of the patients with refractory epilepsy at our hospital during the last 20 years...
November 1, 2011: Revista de Neurologia
Alicia Martínez, Titania Pasqualini, Mirta Stivel, Juan Jorge Heinrich
Adrenal insufficiency is defined by impaired secretion of adrenocortical hormones. It is classified upon the etiology in primary and secondary. Rapid recognition and therapy of adrenocortical crisis are critical to survival. Patients often have nonspecific symptoms: anorexia, vomiting, weakness, fatigue and lethargy. They are followed by hypotension, shock, hypoglicemia, hyponatremia and hyperkalemia. All patients with adrenal insufficiency require urgent fluid reposition, correction of hypoglycemia and glucocorticoid replacement, in order to avoid serious consequences of adrenal crisis...
April 2010: Archivos Argentinos de Pediatría
D Andronesi, A Andronesi, A Tonea, S Andrei, V Herlea, I Lupescu, C Ionescu-Târgovişte, M Coculescu, S Fica, M Ionescu, C Gheorghe, I Popescu
UNLABELLED: Insulinoma is the most frequent neuroendocrine pancreatic tumor and is the main cause for hypoglicemia due to endogenous hyperinsulinism. We performed an analysis of a clinical series in order to study the clinical and biological spectrum of presentation, the preoperatory imagistic diagnosis and results of the surgical approach. Between 1986-2009, 30 patients with symptoms suggesting an insulinoma were hospitalized in our department. Preoperatory localization of insulinomas was possible in 16 patients...
November 2009: Chirurgia
R Baldelli, G Ettorre, G Vennarecci, G Pasimeni, F Carboni, R Lorusso, A Barnabei, M Appetecchia
Insulin-secreting tumors are the commonest hormone-producing neoplasm of the gastrointestinal tract. They occur with an incidence of 4 cases per million per year. About 10% of them are metastatic and malignant insulinomas very rarely observed in children and in elderly. We report a rare case of very large malignant insulinoma in a 71-year-old woman admitted in our Oncological Institute on October 2005. She presented with fasting hypoglicemia (blood glucose 35 mg/dl) and high serum insulin levels (insulin 115...
December 2007: Journal of Experimental & Clinical Cancer Research: CR
Svjetlana Maglajlić, Milos Jesić, Svetislav Necić, Marija Lukac, Sanja Sindjić, Maja Jesić, Dragana Vujović
Persistent hyperinsulinemic hypoglicemia of the neonate is a rare heterogenous disease (clinically, histologically, metabolically and genetically), which is characterized by inadequatly high insuline rates in the presence of severe hypoglicemia. Hyperinsulinism, rather a syndrome than a disease, of which the main metabolic feature is hypoglicemia and decreased concentration of free fatty acids and ketones in serum (insulin inhibits lypolisis and synthesizes ketonic bodies), presents a major diagnostic and therapeutic chalenge...
October 2004: Srpski Arhiv za Celokupno Lekarstvo
P Scarpa, R Chierici, C Fortini
The newborn with seizures should be treated urgently, because of the high risk of consequent brain damage. In addition to general management in order to correct metabolic and functional unbalancement, associated with the fits, specific causes of neonatal seizures (hypoglicemia, hypocalcemia, hypomagnesiemia, hypo-hypernatremia, pyridoxine deficiency) should be immediately removed. If neonatal seizures depend on other non specific causes (anoxia, cerebral hemorrhagy, malformation, infection or other, a symptomatic anticonvulsant treatment should be carried out without delay...
September 1982: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
C Cortés, A Mora, J Torres, M Olivé, E Cabarrocas
We reviewed 18 patients operated on insulinoma during the last 16 years (1974-1990). The previous symptoms, the clinical and biochemical diagnostic procedures, the localization before and during operation, and the medical and surgical treatment are reported. Constant and continuous glucose solution perfusion at the preoperative stage prevented the occurrence of hypoglicemia without interference with the rebound hyperglicemia that follows tumor exeresis. Neuroleptanalgesia with nitrogen protoxide and competitive muscular relaxant agents was satisfactory in all instances...
January 1991: Revista Española de Anestesiología y Reanimación
B Bruni, K Bruni-Bocher, A Della Valle, S Gamba
The recent literature relating to the pathogenesis of diabetic retinopathy, with or without nephropaty, is critically reviewed. Particular attention is given to the Growth Hormone (GH) hypothesis. The various procedures of hypophysectomy are discussed, including the possible ways of suppressing growth hormone production or overproduction by drugs, and expecially by medroxyprogesterone acetate (MAP). Personal results obtained with long-term administration of MAP in deposit form on alternate days in 10 patients with advanced retinopathy are described...
March 21, 1975: Minerva Medica
M Stoopen, L Ize, G Baz, J Aguirre
A Zollinger-Ellison syndrome case is reported. During arteriography and surgical treatment islet cell carcinoma of the pancreas with metastasis to the liver was found. After surgery, patient has presented several periods of hypoglicemia. Hence it was speculated that this type of neoplasm might have double endocrine function.
1975: Archivos de Investigación Médica
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