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https://www.readbyqxmd.com/read/28326847/anti-angiogenic-activity-and-phytochemical-screening-of-fruit-fractions-from-vitex-agnus-castus
#1
Giovanna Certo, Rosaria Costa, Valeria D'Angelo, Marina Russo, Ambrogina Albergamo, Giacomo Dugo, Maria Paola Germanò
Although the antitumour activity of Vitex agnus castus fruits has been already addressed, no work has yet assessed their anti-angiogenic potential. To this purpose, several extractive fractions of such fruits were tested on zebrafish embrios by EAP assay, so that only the bioactive fractions could be subsequently tested on the chick chorioallantoic membrane by CAM assay. Bioactive fractions were also phytochemically screened to identify those bioactive compounds responsible for anti-angiogenic activity. A marked inhibition of vessel formation was detected only in zebrafish embryos treated with chloroform or ethyl acetate fractions...
March 22, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28243425/systematic-review-of-premenstrual-postmenstrual-and-infertility-disorders-of-vitex-agnus-castus
#2
REVIEW
Mahmoud Rafieian-Kopaei, Mino Movahedi
INTRODUCTION: Vitex agnus-castus, also called vitex is aboriginal to the Mediterranean region, with long leaves, tender stem, flowers and ripening seeds. The aim of this study was to overview premenstrual, postmenstrual and infertility disorder of Vitex agnus-castus. METHODS: This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases. The initial search strategy identified about 87 references. In this study, 43 studies were accepted for further screening, and met all our inclusion criteria (in English, full text, therapeutic effects of Vitex agnus-castus and dated mainly from the year 2009 to 2016)...
January 2017: Electronic Physician
https://www.readbyqxmd.com/read/28237870/the-treatment-of-premenstrual-syndrome-with%C3%A2-preparations-of-vitex-agnus-castus-a%C3%A2-systematic-review-and-meta-analysis
#3
REVIEW
Saskia Verkaik, Astrid M Kamperman, Roos van Westrhenen, Peter F J Schulte
OBJECTIVE: Our objective was to determine the efficacy, tolerability, and acceptability of Vitex agnus castus preparations for treatment of premenstrual syndrome. STUDY DESIGN: All journals in the OVID software from inception through January 2016 were searched, including the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, and PsycINFO. Gray literature was searched by Google Scholar and manufacturers of Vitex agnus castus preparations were contacted for information about unpublished trials...
February 22, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28165811/nanoemulsion-for-improving-solubility-and-permeability-of-vitex-agnus-castus-extract-formulation-and-in-vitro-evaluation-using-pampa-and-caco-2-approaches
#4
Vieri Piazzini, Elena Monteforte, Cristina Luceri, Elisabetta Bigagli, Anna Rita Bilia, Maria Camilla Bergonzi
The purpose of this study was to develop new formulation for an improved oral delivery of Vitex agnus-castus (VAC) extract. After the optimization and validation of analytical method for quali-quantitative characterization of extract, nanoemulsion (NE) was selected as lipid-based nanocarrier. The composition of extract-loaded NE resulted in triacetin as oil phase, labrasol as surfactant, cremophor EL as co-surfactant and water. NE contains until 60 mg/mL of extract. It was characterized by DLS and TEM analyses and its droplets appear dark with an average diameter of 11...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/27976124/nanoemulsions-to-enhance-oral-bioavailability-of-vitex-agnus-castus-extract
#5
V Piazzini, E Monteforte, C Luceri, E Bigagli, C Guccione, A R Bilia, M C Bergonzi
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27822252/effects-of-hydro-alcoholic-extract-of-vitex-agnus-castus-fruit-on-kidney-of-d-galactose-induced-aging-model-in-female-mice
#6
A A Oroojan, A Ahangarpour, L Khorsandi, S A Najimi
The aim of the present study was to evaluate the effect of a hydro-alcoholic extract of Vitex agnus-castus (VAC) fruit on blood urea nitrogen (BUN), creatinine (Cr) and, kidney histology of a female mouse model of D-galactose induced aging. In this experimental study, 72 NMRI mice were divided into 6 groups: control, VAC, D-galactose, D-galactose+VAC, aging, and aging+VAC. D-galactose was injected for 45 days and, VAC extract administered in the last 7 days, twice a day. Serum BUN and Cr levels were not significantly changed in the D-galactose and natural aged animals in comparison to control group...
2016: Iranian journal of veterinary research
https://www.readbyqxmd.com/read/27677719/botanicals-and-their-bioactive-phytochemicals-for-women-s-health
#7
REVIEW
Birgit M Dietz, Atieh Hajirahimkhan, Tareisha L Dunlap, Judy L Bolton
Botanical dietary supplements are increasingly popular for women's health, particularly for older women. The specific botanicals women take vary as a function of age. Younger women will use botanicals for urinary tract infections, especially Vaccinium macrocarpon (cranberry), where there is evidence for efficacy. Botanical dietary supplements for premenstrual syndrome (PMS) are less commonly used, and rigorous clinical trials have not been done. Some examples include Vitex agnus-castus (chasteberry), Angelica sinensis (dong quai), Viburnum opulus/prunifolium (cramp bark and black haw), and Zingiber officinale (ginger)...
October 2016: Pharmacological Reviews
https://www.readbyqxmd.com/read/27661281/-study-of-lipids-seed-s-oil-of-vitex-agnus-castus-growing-in-georgia
#8
B Kikalishvili, D Zurabashvili, Ts Sulakvelidze, M Malania, D Turabelidze
There was established the lipid composition of the seeds of Vitex agnus castus L. by the qualitative and quantitative methods of analyses. There were received neutral lipids from the seeds by extraction with hexane in the yield 10%, counted on dry material. For the divide of neutral lipids there was used silica gel plates LS 5/40 in the systems of solvents: 1. petroleum ether-diethylether-acidum aceticum (85:14:1), 2. hexane-diethylether (1:1). After obtaining neutral lipids from the residual plant shrot pollar lipids was extracted with the mixture of chloroform-methanol (2:1) and was divided on silica gel plates LS 5/40, mobile phase: 1...
July 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27595438/effects-of-vitex-agnus-castus-fruit-on-sex-hormones-and-antioxidant-indices-in-a-d-galactose-induced-aging-female-mouse-model
#9
Akram Ahangarpour, Seyedeh Asma Najimi, Yaghoob Farbood
BACKGROUND: Aging is associated with the loss of endocrine function. In this study, Vitex agnus-castus (Vitex), which has antioxidant effects and high levels of phytoestrogen, was investigated with regard to the hypothalamic-pituitary-gonadal axis and antioxidant indices in natural aging and in a d-galactose induced aging model in female mice. METHODS: The mice were subcutaneously injected with d-galactose (500 mg/kg/d for 45 days). Extract of Vitex (600 mg/kg/bid for 7 days by gavage) was used to treat d-galactose-induced aging and natural aging in mice...
November 2016: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/27508987/chemical-composition-and-acaricidal-activity-of-the-essential-oils-from-vitex-agnus-castus-l-verbenaceae-and-selected-monoterpenes
#10
Roberta C S Neves, Claudio A G da Camara
Tetranychus urticae is considered one of the main plagues in the world. Its occurrence in Pernambuco was registered for the first time in 1985 and it has caused considerable damage to the farmers, attacking different cultures of agricultural interest. The essential oils from different parts of Vitex agnus-castus harvested in the Atlantic forest in the state of Pernambuco, Brazil, were obtained by hydrodistillation and the acaricidal potential was evaluated against Tetranychus urticae using two methods under laboratory conditions...
September 2016: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/27476882/functional-morphology-of-pituitary-thyroid-and-adrenocortical-axes-in-middle-aged-male-rats-treated-with-vitex-agnus-castus-essential-oil
#11
Branka Šošić-Jurjević, Vladimir Ajdžanović, Branko Filipović, Svetlana Trifunović, Ivana Jarić, Nataša Ristić, Verica Milošević
We previously reported that Vitex agnus-castus L. essential oil (VACEO), when administered to middle-aged males, exerts a bone-protective effect, induces silencing of locomotor activities and decreases pituitary prolactin immunopositivity. To further assess the putative endocrine effects of VACEO, we examined the pituitary-thyroid and -adrenocortical axes in our model. Sixteen-month-old Wistar rats were subcutaneously administered 60mg/kg of VACEO dissolved in sterile olive oil, while the control group received the same amount of vehicle alone for three weeks...
September 2016: Acta Histochemica
https://www.readbyqxmd.com/read/27462550/effects-of-flaxseed-and-hypericum-perforatum-on-hot-flash-vaginal-atrophy-and-estrogen-dependent-cancers-in-menopausal-women-a-systematic-review-and-meta-analysis
#12
REVIEW
Masumeh Ghazanfarpour, Ramin Sadeghi, Robab Latifnejad Roudsari, Talat Khadivzadeh, Imaneh Khorsand, Maliheh Afiat, Mahdi Esmaeilizadeh
OBJECTIVE: In this study, we aimed at evaluation of the efficacy of Hypericum perforatum and flaxseed on hot flash, vaginal atrophy and estrogen-dependent cancers in menopausal women. MATERIALS AND METHODS: We searched MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials (RCT) to explore trials that assessed the effectiveness of H. perforatum and flaxseed on hot flash, vaginal atrophy and estrogen-dependent cancers. In this regard, the following terms were used "menopause AND H...
May 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27188194/authentication-of-the-botanical-origin-of-western-herbal-products-using-cimicifuga-and-vitex-products-as-examples
#13
REVIEW
Sayaka Masada
Various herbal medicines have been developed and used in various parts of the world for thousands of years. Although locally grown indigenous plants were originally used for traditional herbal preparations, Western herbal products are now becoming popular in Japan with the increasing interest in health. At the same time, there are growing concerns about the substitution of ingredients and adulteration of herbal products, highlighting the need for the authentication of the origin of plants used in herbal products...
July 2016: Journal of Natural Medicines
https://www.readbyqxmd.com/read/26904176/vitex-agnus-castus-extract-improves-learning-and-memory-and-increases-the-transcription-of-estrogen-receptor-%C3%AE-in-hippocampus-of-ovariectomized-rats
#14
Mohammad Allahtavakoli, Najmeh Honari, Iran Pourabolli, Mohammad Kazemi Arababadi, Hossein Ghafarian, Ali Roohbakhsh, Ali Esmaeili Nadimi, Ali Shamsizadeh
INTRODUCTION: Lower level of estrogen hormone is considered as an important factor for loss of learning and memory in postmenopausal women. Although estrogen replacement therapy is used for compensation, but long-term usage of estrogen is associated with a higher risk of hormone-dependent cancers. Phytoestrogens, due to fewer side effects, have been proposed to prevent menopause-related cognitive decline. METHODS: 24 female Wistar rats weighing 180-220 g were used in this study...
July 2015: Basic and Clinical Neuroscience
https://www.readbyqxmd.com/read/26887532/a-critical-approach-to-evaluating-clinical-efficacy-adverse-events-and-drug-interactions-of-herbal-remedies
#15
REVIEW
Angelo A Izzo, Sung Hoon-Kim, Rajan Radhakrishnan, Elizabeth M Williamson
Systematic reviews and meta-analyses represent the uppermost ladders in the hierarchy of evidence. Systematic reviews/meta-analyses suggest preliminary or satisfactory clinical evidence for agnus castus (Vitex agnus castus) for premenstrual complaints, flaxseed (Linum usitatissimum) for hypertension, feverfew (Tanacetum partenium) for migraine prevention, ginger (Zingiber officinalis) for pregnancy-induced nausea, ginseng (Panax ginseng) for improving fasting glucose levels as well as phytoestrogens and St John's wort (Hypericum perforatum) for the relief of some symptoms in menopause...
May 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/26860808/effects-of-vitex-agnus-and-flaxseed-on-cyclic-mastalgia-a-randomized-controlled-trial
#16
RANDOMIZED CONTROLLED TRIAL
Mojgan Mirghafourvand, Sakineh Mohammad-Alizadeh-Charandabi, Parivash Ahmadpour, Yousef Javadzadeh
OBJECTIVES: Evidence on the effect of Vitex agnus and Flaxseed on cyclical mastalgia is not enough. This study aimed to assess the efficacy of V. agnus and Flaxseed on cyclical mastalgia. DESIGN AND SETTING: This randomized controlled trial was conducted on 159 women referred to health centers of Tabriz, Iran. Subjects were allocated into three groups (n=53 per group) using block randomization. INTERVENTIONS AND MAIN OUTCOME MEASURES: Group I received 25g daily Flaxseed powder and placebo of V...
February 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/26833541/determination-and-identification-of-a-specific-marker-compound-for-discriminating-shrub-chaste-tree-fruit-from-agnus-castus-fruit-based-on-lc-ms-metabolic-analysis
#17
Tadahiro Yahagi, Sayaka Masada, Naohiro Oshima, Ryuta Suzuki, Hiroshi Matsufuji, Yutaka Takahashi, Masato Watanabe, Shoji Yahara, Osamu Iida, Nobuo Kawahara, Takuro Maruyama, Yukihiro Goda, Takashi Hakamatsuka
Shrub Chaste Tree Fruit (SCTF) is defined as the fruits of Vitex rotundifolia L. f. and V. trifolia L. and has been used as a component of some traditional Japanese medicines (Kampo formulations). Agnus Castus Fruit (ACF) is defined as the dried ripe fruits of V. agnus-castus L.; it is used in traditional European medicines, but is becoming popular in Japan as both an over-the-counter drug and as an ingredient in health foods for treating premenstrual syndrome (PMS). To ensure the efficacy and safety of both SCTF and ACF products, it is important to precisely authenticate their botanical origins and to clearly distinguish between SCTF and ACF...
2016: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/26788874/-evaluation-of-the-efficacy-of-a-new-nutraceutical-product-in-the-treatment-of-postmenopausal-symptoms
#18
V Cappelli, G Morgante, A Di Sabatino, M G Massaro, V De Leo
The onset of vasomotor symptoms in postmenopausal women represents the beginning of a hard period from the emotional point of view which involves some of the most important neurotransmitters. Hot flushes and insomnia associated with a state of anxiety that affect postmenopausal women are included in an index known as the Kupperman Index. The use of nutraceuticals in Italy is increasingly widespread, and only 6-8% of women currently choose to take hormone replacement therapy. The action of these natural supplements primarily depends on the selection of substances and the dose of each single ingredient...
December 2015: Minerva Ginecologica
https://www.readbyqxmd.com/read/26611404/study-on-chemical-analysis-antioxidant-and-in-vitro-antifungal-activities-of-essential-oil-from-wild-vitex-agnus-castus-l-seeds-growing-in-area-of-argan-tree-of-morocco-against-clinical-strains-of-candida-responsible-for-nosocomial-infections
#19
A Asdadi, A Hamdouch, A Oukacha, R Moutaj, S Gharby, H Harhar, M El Hadek, B Chebli, L M Idrissi Hassani
OBJECTIVE: To study the composition, the antioxidant activity and the in vitro antifungal action anti-Candida species of essential oils extracted from seeds of Vite xagnus-castus L. MATERIALS AND METHOD: The essential oils were extracted using Clevenger-type apparatus and analyzed by gas chromatography/mass spectrometry (GC/MS). The antioxidant activity was analyzed using the DPPH free radical-scavenging method. Susceptibility tests for Candida albicans (12), C...
December 2015: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/26321116/casticin-an-active-compound-isolated-from-vitex-fructus-ameliorates-the-cigarette-smoke-induced-acute-lung-inflammatory-response-in-a-murine-model
#20
Hyeonhoon Lee, Kyung-Hwa Jung, Hangyul Lee, Soojin Park, Woosung Choi, Hyunsu Bae
The aim of this study was to determine of the effect of casticin, as an anti-inflammatory agent, on an acute lung inflammation in vivo model established through exposure to cigarette smoke (CS). Casticin is a phytochemical from Vitex species such as Vitex rotundifolia and Vitex agnus-castus that was recently shown to exert an anti-inflammatory effect in vivo. To demonstrate the effects of casticin, C57BL/6 mice were whole-body exposed to mainstream CS or fresh air for two weeks and treated with 1, 2, and 10mg/kg casticin via an i...
October 2015: International Immunopharmacology
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