keyword
https://read.qxmd.com/read/38497692/the-stimulation-of-exosome-generation-by-visfatin-polarizes-m2-macrophages-and-enhances-the-motility-of-chondrosarcoma
#1
JOURNAL ARTICLE
Chang-Yu Song, Chih-Ying Wu, Chih-Yang Lin, Chun-Hao Tsai, Hsien-Te Chen, Yi-Chin Fong, Li-Chai Chen, Chih-Hsin Tang
Chondrosarcoma is a malignant bone tumor that arises from abnormalities in cartilaginous tissue and is associated with lung metastases. Extracellular vesicles called exosomes are primarily used as mediators of intercellular signal transmission to control tumor metastasis. Visfatin is an adipokine reported to enhance tumor metastasis, but its relationship with exosome generation in chondrosarcoma motility remains undetermined. Our results found that overexpressing visfatin augments the production of exosomes from chondrosarcoma cells...
March 18, 2024: Environmental Toxicology
https://read.qxmd.com/read/38497306/is-membrane-androgen-and-estrogen-receptor-signaling-imperative-in-the-governing-function-of-the-adrenal-cortex-in-the-eurasian-beaver-castor-fiber-l
#2
JOURNAL ARTICLE
G Lonc, A Hrabia, I Krakowska, A J Korzekwa, M Zarzycka, D Wolak, M Wajdzik, M Kotula-Balak
There is a need to fully know the physiology of Eurasian beaver due to its essential role in environmental homeostasis. However, a "human factor" impacts this, including stress conditions and environmental pollution. Adrenal glands protect these all. The regulation of endocrine processes by nonclassical androgen and estrogen signaling, the first and fastest control, is still a matter of research. The specific analyses performed here in mature female and male beaver adrenals contained: anatomical and histological examinations, expression and localization of membrane androgen receptor (zinc transporter, Zinc- and Iron-like protein 9; ZIP9) and membrane estrogen receptor coupled with G protein (GPER), and measurement of zinc (Zn2+ ) and copper (Ca2+ ) ion levels and corticosterone levels...
March 18, 2024: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://read.qxmd.com/read/38497283/the-role-of-aryl-hydrocarbon-receptor-in-the-pathogenesis-and-treatment-of-psoriasis
#3
REVIEW
Xiran Lin, Xianmin Meng, Jingrong Lin
The pathogenesis of psoriasis is complex. Aryl hydrocarbon receptor (AhR) is a transcription factor that can be bound and activated by structurally diverse ligands and plays an important role in a range of biological processes and in the pathogenesis of different diseases. Recently, the role of AhR in psoriasis has attracted attention. AhR has toxicological functions and physiological functions. The overexpression and activation of AhR induced by the environmental pollutant and exogenous AhR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) can drive the development of psoriasis...
March 18, 2024: Journal of Cutaneous Medicine and Surgery
https://read.qxmd.com/read/38497272/a-ratiometric-fluorescent-probe-with-a-large-stokes-shift-for-the-detection-of-hg2-and-its-applications-in-environmental-sample-and-living-system-analysis
#4
JOURNAL ARTICLE
Jixiang Tian, Xuechun Tian, Shuai Gong, Yueyin Liang, Zhiyuan Meng, Weiqi Liu, Xu Xu, Zhonglong Wang, Shifa Wang
Toxic mercury ions (Hg2+) can cause serious environmental pollution and accumulate in living organisms via the food chain. Therefore, monitoring Hg2+ is crucial in ensuring the safety of ecosystems and organisms. In this work, a novel ratiometric fluorescent probe CMT (5-(4-(diphenylamino)phenyl)-1-(7-hydroxy-coumarin-3-yl)-4-pentene-1,3-dione) based on coumarin was developed for detecting Hg2+, which displayed obvious fluorescence changes, a low detection limit (2.24 × 10-7 M), good selectivity, and a large Stokes shift (255 nm)...
March 18, 2024: Analytical Methods: Advancing Methods and Applications
https://read.qxmd.com/read/38497020/lignin-based-nanospheres-as-environmental-remediation-platforms-for-anionic-dye-contaminants
#5
JOURNAL ARTICLE
Fei Zhang, Ha Na, Jake Carrier, Chen-Yu Chang, Daniela Radu, Cheng-Yu Lai
Modern manufacturing of textiles, pharmaceuticals, food, cosmetics, plastics, paper, etc. involves the utilization of anionic and cationic dyes that lead to significant water contamination. Recent research has explored the use of nanomaterials toward developing nanoadsorbents for water decontamination caused by industrial pollution. Here, we report on a novel platform for anionic dye remediation, consisting of a polyethylenimine-functionalized lignin nanosphere (PEI-LNS). The designed nanomaterial shows significant ability to adsorb an anionic dye selected as a proof-of-concept-Sulforhodamine B, from aqueous solutions...
March 12, 2024: ACS Omega
https://read.qxmd.com/read/38497018/camel-dung-derived-biochar-for-the-removal-of-copper-ii-and-chromium-iii-ions-from-aqueous-solutions-adsorption-and-kinetics-studies
#6
JOURNAL ARTICLE
Kenesha Wilson, Jibran Iqbal, Amira Obaid Abdalla Obaid Hableel, Zainab Naji Khalaf Beyaha Alzaabi, Yousef Nazzal
This study explores an innovative approach to tackle the critical issue of heavy metal ion contamination in aqueous solutions through the utilization of camel dung-derived biochar. In the context of global environmental concerns and the adverse impacts of heavy metal pollution on ecosystems and human health, the investigation focuses on copper(II) and chromium(III) ions, which are among the most pervasive pollutants originating from industrial activities. The research revealed that camel dung-derived biochar exhibits exceptional potential for the removal of copper(II) and chromium(III) ions, with removal efficiencies of more than 90% and adsorption capacities of 23...
March 12, 2024: ACS Omega
https://read.qxmd.com/read/38496835/optimization-of-hybrid-renewable-diesel-power-plants-considering-operational-cost-battery-degradation-and-emissions
#7
JOURNAL ARTICLE
Aya Amer, Ahmed Massoud, Khaled Shaban
Renewable energy sources have immense potential for enhancing environmental sustainability; however, addressing their intermittency and irregularity is vital for optimizing economic benefits within microgrids. Integrating renewable energy systems with energy storage presents a promising solution. This study introduces an innovative energy management system designed for hybrid renewable power stations, incorporating battery energy storage systems and diesel generators. By accounting for battery degradation costs associated with charge depth and lifespan, the study transforms long-term battery expenses into real-time operational costs...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38496350/precursor-and-waste-free-synthesis-of-spark-ablated-nanoparticles-with-enhanced-photocatalytic-activity-and-stability-towards-airborne-organic-pollutant-degradation
#8
JOURNAL ARTICLE
Sarka Drdova, Min Gao, Olga Sambalova, Robin Pauer, Zhouping Zhou, Sofia Dimitriadou, Andreas Schmidt-Ott, Jing Wang
Photocatalyst synthesis typically involves multiple steps, expensive precursors, and solvents. In contrast, spark ablation offers a simple process of electrical discharges in a gap between two electrodes made from a desirable material. This enables a precursor- and waste-free generation of pure metal oxide nanoparticles or mixtures of various compositions. This study presents a two-step method for the production of photocatalytic filters with deposited airborne MnO x , TiO2 , and ZnO nanoparticles using spark ablation and calcination processes...
March 14, 2024: Environmental Science. Nano
https://read.qxmd.com/read/38496327/enhancing-spatial-inference-of-air-pollution-using-machine-learning-techniques-with-low-cost-monitors-in-data-limited-scenarios
#9
JOURNAL ARTICLE
Leonardo Y Kamigauti, Gabriel M P Perez, Thomas C M Martin, Maria de Fatima Andrade, Prashant Kumar
Ensuring environmental justice necessitates equitable access to air quality data, particularly for vulnerable communities. However, traditional air quality data from reference monitors can be costly and challenging to interpret without in-depth knowledge of local meteorology. Low-cost monitors present an opportunity to enhance data availability in developing countries and enable the establishment of local monitoring networks. While machine learning models have shown promise in atmospheric dispersion modelling, many existing approaches rely on complementary data sources that are inaccessible in low-income areas, such as smartphone tracking and real-time traffic monitoring...
March 14, 2024: Environ Sci Atmos
https://read.qxmd.com/read/38496321/hexaconazole-exposure-may-lead-to-parkinson-via-disrupting-glucocerebrosidase-and-parkin-molecular-interaction-dynamics-mmpbsa-and-dft-based-in-silico-predictive-toxicology
#10
JOURNAL ARTICLE
Faisal K Alkholifi, Sayed Aliul Hasan Abdi, Marwa Qadri, Shabihul Fatma Sayed, Amani Khardali, Sumathi Nagarajan, Alhamyani Abdulrahman, Nayef Aldabaan, Yahia Alghazwani
Hexaconazole is a known fungicide for agricultural purposes. It has bioaccumulation ability which makes it important for its toxicological characterization. There are various neurological impacts of pollutants on human health. Therefore, in this study, we have done predictive analyses of the interaction mechanism of hexaconazole by molecular interaction analysis, molecular dynamics simulation, and Poisson-Boltzmann surface area (MM-PBSA) to assess hexaconazole's potency to disrupt the homeostasis of glucocerebrosidase (-7...
February 2024: Toxicology Research
https://read.qxmd.com/read/38496226/the-effect-of-air-pollution-and-climate-change-on-sleep
#11
REVIEW
Semih Ayta
Research has shown that air pollution and climate change affect both the duration and quality of sleep; threatens physical and mental health especially through respiratory, cardiovascular, and nervous systems; and shortens life expectancy. This review will begin with overall information on air pollution, climate change and sleep. Then, it will proceed with the effects of these two environmental issues on sleep, in the light of previous research.
2024: Noro Psikiyatri Arsivi
https://read.qxmd.com/read/38495797/a-study-on-environmental-impact-of-slow-moving-electric-vehicles-using-microsimulation-on-lucknow-urban-road-with-an-on-ramp
#12
JOURNAL ARTICLE
Mohd Sadat, Syed Aqeel Ahmad, Mehmet Ali Silgu, Shrish Bajpai, Digvijay Pandey
BACKGROUND: The adoption of electric vehicles for mobility is seen as a major step towards the conservation of the environment. In India, slow-moving Electric 3-Wheelers (E3Ws) have been adopted for last-mile connectivity. The present study investigated the impact of slow-moving electric 3-wheelers on the environment in terms of emissions and traffic performance in mixed conditions. METHODS: Field traffic data from a section of road in the city of Lucknow was collected and used for the calibration of the traffic model...
2024: Environmental Health Insights
https://read.qxmd.com/read/38495796/level-of-heavy-metals-in-fish-and-associated-human-health-risk-from-the-omo-delta-in-southern-ethiopia-a-first-hand-report
#13
JOURNAL ARTICLE
Abiy Andemo Kotacho, Girma Tilahun Yimer, Solomon Sorsa Sota, Yohannes Seifu Berego
This study was the first to investigate the levels of heavy metals in commercially important fish species ( Lates niloticus and Oreochromis niloticus ) and the human health risk in Southern Ethiopia. Sixty fish samples were collected from the Omo delta. The target hazard quotient (THQ), hazard index (HI), and target cancer risk (TCR) were used to estimate the human health risks. The mean levels of heavy metals detected in the liver and muscle of Lates niloticus generally occurred in the order of Fe> Zn > Pb > Cu >Mn> Cr > Co > Ni and Fe > Pb > Zn >Mn > Cu > Co > Cr >Ni, respectively...
2024: Environmental Health Insights
https://read.qxmd.com/read/38495754/impact-of-the-coronavirus-disease-2019-pandemic-on-the-diversity-of-notifiable-infectious-diseases-a-case-study-in-shanghai-china
#14
JOURNAL ARTICLE
Yongfang Zhang, Wenli Feng
The outbreak of coronavirus disease 2019 (COVID-19) has not only posed significant challenges to public health but has also impacted every aspect of society and the environment. In this study, we propose an index of notifiable disease outbreaks (NDOI) to assess the impact of COVID-19 on other notifiable diseases in Shanghai, China. Additionally, we identify the critical factors influencing these diseases using multivariate statistical analysis. We collected monthly data on 34 notifiable infectious diseases (NIDs) and corresponding environmental and socioeconomic factors (17 indicators) from January 2017 to December 2020...
2024: PeerJ
https://read.qxmd.com/read/38495524/association-between-early-life-exposure-to-agriculture-biodiversity-and-green-space-and-risk-of-inflammatory-bowel-disease-a-population-based-cohort-study
#15
JOURNAL ARTICLE
Manasi Agrawal, Anne V Hansen, Jean-Frederic Colombel, Tine Jess, Kristine H Allin
BACKGROUND: Specific pollutants and environmental exposures are implicated in modulating inflammatory bowel disease (IBD) risk. However, the role of environmental exposures, particularly during the early life period, towards IBD risk, has not been systematically evaluated. METHODS: We conducted a nationwide population-based cohort study during the study period extending from January 1, 1995, to September 1, 2020, using cross-linked Danish registers, maps, and inventories to ascertain the impact of agricultural land use, biodiversity, green space, urban space, blue space, and normalized difference vegetation index during pregnancy and the first two years of life on IBD, Crohn's disease (CD), and ulcerative colitis (UC) risk, using adjusted Cox proportional hazards regression analyses...
April 2024: EClinicalMedicine
https://read.qxmd.com/read/38495153/infancy-of-peracetic-acid-activation-by-iron-a-new-fenton-based-process-a-review
#16
REVIEW
Iván Sciscenko, Davide Vione, Marco Minella
The exacerbated global water scarcity and stricter water directives are leading to an increment in the recycled water use, requiring the development of new cost-effective advanced water treatments to provide safe water to the population. In this sense, peracetic acid (PAA, CH3 C(O)OOH) is an environmentally friendly disinfectant with the potential to challenge the dominance of chlorine in large wastewater treatment plants in the near future. PAA can be used as an alternative oxidant to H2 O2 to carry out the Fenton reaction, and it has recently been proven as more effective than H2 O2 towards emerging pollutants degradation at circumneutral pH values and in the presence of anions...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38494947/translational-relevance-of-rodent-models-to-predict-human-liver-disease
#17
JOURNAL ARTICLE
Debabrata Mahapatra, Robert Maronpot
Animals models are essential to understand the complex pathobiology of human diseases. George Box's aphorism based on statistics "All models are wrong, but some are useful" certainly applies to animal models of disease. In this session, the translational relevance of various animal models applicable to human liver disease was explored starting with a historic overview of the rodent cancer bioassay with emphasis on hepatocarcinogenesis from early work at the National Cancer Institute, refinement by the National Toxicology Program and contemporary efforts to identify potential mechanisms and their relevance to human cancer risk...
March 18, 2024: Toxicologic Pathology
https://read.qxmd.com/read/38494751/mitigation-strategies-for-heavy-metal-toxicity-and-its-negative-effects-on-soil-and-plants
#18
JOURNAL ARTICLE
Quanheng Li, Imran
Heavy metal pollution threatens food security by accumulating in crops and soils, posing a significant challenge to modern agriculture due to its high toxicity. Urgent action is needed to restore affected agricultural fields. An efficient way to remove toxins is by bioremediation, which uses microorganisms. With the purpose of restoring soil in agriculture, this research attempts to assemble a consortium of microorganisms isolated from techno-genic soil. A number of promising strains, including Pseudomonas putida , Pantoea sp...
March 17, 2024: International Journal of Phytoremediation
https://read.qxmd.com/read/38494707/association-between-short-term-exposure-to-ambient-air-pollutants-and-biomarkers-indicative-of-inflammation-and-oxidative-stress-a-cross-sectional-study-using-koges-hexa-data
#19
JOURNAL ARTICLE
Ji Hyun Kim, Hae Dong Woo, Jane J Lee, Dae Sub Song, Kyoungho Lee
BACKGROUND: Air pollution-induced systemic inflammation and oxidative stress are hypothesized to be the major biological mechanisms underlying pathological outcomes. We examined the association between short-term exposure to ambient air pollutants and biomarkers of inflammation and oxidative stress in 2199 general middle-aged Korean population residing in metropolitan areas. METHODS: Serum levels of inflammatory cytokines (interleukin [IL]-1β, IL-6, IL-8, IL-10, and tumor necrosis factor [TNF]-α) and urinary levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG) were measured...
2024: Environmental Health and Preventive Medicine
https://read.qxmd.com/read/38494706/association-between-excessive-screen-time-and-school-level-proportion-of-no-family-rules-among-elementary-school-children-in-japan-a-multilevel-analysis
#20
JOURNAL ARTICLE
Masaaki Yamada, Michikazu Sekine, Takashi Tatsuse
BACKGROUND: Excessive screen time (ST) in children is a global concern. We assessed the association between individual- and school-level factors and excessive ST in Japanese children using a multilevel analysis. METHODS: A school-based cross-sectional study was conducted in Toyama, Japan in 2018. From 110 elementary schools in Toyama Prefecture, 13,413 children in the 4th-6th grades (boys, 50.9%; mean, 10.5 years old) participated. We assessed lifestyle, recreational ST (not for study use), psychological status, and school and family environment including family rules...
2024: Environmental Health and Preventive Medicine
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