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Growth accommodating valve prosthesis

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https://www.readbyqxmd.com/read/25441796/tricuspid-valve-replacement-with-a-melody-stented-bovine-jugular-vein-conduit
#1
Joshua L Hermsen, Lester C Permut, Tim C McQuinn, Thomas K Jones, Jonathan M Chen, David Michael McMullan
Atrioventricular valve replacement options are limited in infants and small children. The Melody stented bovine jugular vein conduit is being used with increasing frequency for percutaneous pulmonary valve replacement. The Melody valve can be serially dilated over time to accommodate the somatic growth of pediatric patients. We report the initial experience of using the Melody valve as a surgical tricuspid valve replacement in an infant.
November 2014: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/24969934/-stent-implantation-for-relief-of-pulmonary-artery-branch-stenosis
#2
Ying Guo, Zhiqing Yu, Tingliang Liu, Wei Gao, Meirong Huang, Fen Li, Lijun Fu, Pengjun Zhao
OBJECTIVE: Branch pulmonary artery stenosis is one of the common congenital heart disease. Stent implantation to relieve branch pulmonary artery stenosis (BPAS) is an alternative to failed surgical or balloon angioplasty. The aim of this study was to explore the indication, methods and complications of using balloon expandable stent placement to treat branch pulmonary artery stenosis, and evaluate the results of stent implantation in the treatment of branch pulmonary artery stenosis. METHOD: From August 2005 to December 2012, 19 patients underwent an attempt at stent implantation...
May 2014: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/24332108/stented-bovine-jugular-vein-graft-melody-valve-for-surgical-mitral-valve-replacement-in-infants-and-children
#3
Luis G QuiƱonez, Roger Breitbart, Wayne Tworetsky, James E Lock, Audrey C Marshall, Sitaram M Emani
OBJECTIVE: The options for mitral valve replacement in children with irreparable mitral valve disease have been limited to fixed-diameter prostheses that do not accommodate for somatic growth. We have modified an externally stented bovine jugular vein graft (Melody valve) for implantation in this cohort. Because it is not a fixed-diameter prosthesis, we hypothesized that the valve can be expanded in the catheterization laboratory as the child grows. METHODS: The medical records of patients who had undergone Melody valve implantation in the mitral or left atrioventricular valve position from 2010 to 2013 were reviewed...
October 2014: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/21315575/heart-valve-tissue-engineering-quo-vadis
#4
REVIEW
Frederick J Schoen
Surgical replacement of diseased heart valves by mechanical and tissue valve substitutes is now commonplace and generally enhances survival and quality of life. However, a fundamental problem inherent to the use of existing mechanical and biological prostheses in the pediatric population is their failure to grow, repair, and remodel. A tissue engineered heart valve could, in principle, accommodate these requirements, especially somatic growth. This review provides a brief overview of the field of heart valve tissue engineering, with emphasis on recent studies and evolving concepts, especially those that establish design criteria and key hurdles that must be surmounted before clinical implementation...
October 2011: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/20523298/human-or-animal-homograft-could-they-have-a-future-as-a-biological-scaffold-for-engineered-heart-valves
#5
REVIEW
L Dainese, P Biglioli
Tissue-engineered heart valves (TEHVs) promise to be the ideal heart valve replacement: they have the potential to grow and repair within the host, to minimise inflammatory and immunological responses and to limit thromboembolism. Viable cells included in TEHVs can theoretically adapt to a growing and changing environment exactly as a native biological structure. This could be extremely important in case of paediatric applications, where reoperations are frequently required to replace failed valve substitutes or to accommodate the growth of the patient...
June 2010: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/19413511/bioengineering-challenges-for-heart-valve-tissue-engineering
#6
REVIEW
Michael S Sacks, Frederick J Schoen, John E Mayer
Surgical replacement of diseased heart valves by mechanical and tissue valve substitutes is now commonplace and enhances survival and quality of life for many patients. However, repairs of congenital deformities require very small valve sizes not commercially available. Further, a fundamental problem inherent to the use of existing mechanical and biological prostheses in the pediatric population is their failure to grow, repair, and remodel. It is believed that a tissue engineered heart valve can accommodate many of these requirements, especially those pertaining to somatic growth...
2009: Annual Review of Biomedical Engineering
https://www.readbyqxmd.com/read/15915872/heart-valve-regeneration
#7
REVIEW
Elena Rabkin-Aikawa, John E Mayer, Frederick J Schoen
The valves of the heart cannot regenerate spontaneously. Therefore, heart valve disease generally necessitates surgical repair or replacement of the diseased tissue by mechanical or bioprosthetic valve substitutes in order to avoid potentially fatal cardiac or systemic consequences. Although survival and quality of life is enhanced for many patients treated surgically, currently available valve substitutes remain imperfect. This is especially the case in pediatric applications, where physiologically corrective procedures can be successfully performed, but reoperations are frequently required to replace failed valve substitutes or accommodate growth of the patient...
2005: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/8694603/aortic-root-replacement-with-the-pulmonary-autograft-in-children-with-complex-left-heart-obstruction
#8
V A Starnes, G B Luciani, W J Wells, R B Allen, A B Lewis
BACKGROUND: The optimal surgical treatment of complex (multiple level or recurrent) left ventricular outflow tract obstruction (LVOTO) in infancy is controversial. Staged procedures expose the children to the need for reoperation, and currently available techniques of aortoventriculoplasty are associated with the morbidities of biological and mechanical prostheses. METHODS: Between July 1992 and January 1996, we have performed 24 aortic root replacements with the pulmonary autograft in pediatric patients (< 18 years)...
August 1996: Annals of Thoracic Surgery
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