keyword
https://read.qxmd.com/read/38536440/circulating-catecholamines-endothelin-1-and-nitric-oxide-releases-do-not-explain-the-preserved-fmd-following-acute-resistance-exercise-in-strength-trained-men
#1
JOURNAL ARTICLE
Takuma Morishima, Nobukazu Kasai
PURPOSE: Acute resistance exercise decreases endothelial function in sedentary individuals but not in strength-trained (ST) individuals. However, the underlying mechanism(s) of vascular protection in ST individuals remains unclear. Herein, we compared catecholamines, endothelin-1 (ET-1), and nitric oxide (NOx) releases after acute resistance exercise between sedentary and ST individuals. METHODS: The untrained (UT) group comprised 12 male individuals with no regular training, while the ST group comprised 12 male individuals...
March 27, 2024: European Journal of Applied Physiology
https://read.qxmd.com/read/38535114/early-atherosclerosis-in-familial-hypercholesterolemia-patients-significance-of-vascular-markers-for-risk-stratification
#2
JOURNAL ARTICLE
Urte Aliosaitiene, Zaneta Petrulioniene, Egidija Rinkuniene, Antanas Mainelis, Jurate Barysiene, Urte Smailyte, Vaida Sileikiene, Aleksandras Laucevicius
BACKGROUND: Familial hypercholesterolemia (FH) is a genetic disorder that manifests as impaired low-density lipoprotein cholesterol (LDL-C) metabolism, resulting in lifelong exposure to high cholesterol levels and increased risk of cardiovascular disease (CVD). There is heterogeneity in cardiovascular risk for FH patients, so risk stratification is of utmost importance. The aim of this study was to evaluate the impact of increases in LDL-C and the impact of other CVD risk factors on vascular markers in the FH patient population...
March 13, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38524399/a-cross-sectional-study-evaluating-the-association-of-brachial-artery-flow-mediated-vasodilation-with-physical-activity-measured-by-accelerometry-in-patients-with-the-overlap-of-obstructive-sleep-apnea-and-chronic-obstructive-pulmonary-disease
#3
JOURNAL ARTICLE
Madalina Macrea, Atul Malhotra, Richard ZuWallack, Krisann Oursler, Richard Casaburi
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in Overlap Syndrome (OS), the co-occurrence of Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease. Clustering of patients in subgroups with similar pre-clinical manifestations (ie, endothelial dysfunction) may identify relevant therapeutic phenotype categories for patients with OS who are at high risk of CVD. We therefore conducted a cross-sectional pilot study of endothelial function in 7 patients with OS (Forced Expiratory Volume in 1 second/Forced Vital Capacity < 0...
2024: International Journal of Chronic Obstructive Pulmonary Disease
https://read.qxmd.com/read/38524158/restless-legs-syndrome-periodic-limb-movements-of-sleep-and-subclinical-cardiovascular-disease
#4
JOURNAL ARTICLE
Kevin J Hochstrasser, Steven C Rogers, Arshed Quyyumi, Dayna Johnson, Victoria Pak, Amit J Shah, David B Rye, Lynn Marie Trotti
UNLABELLED: Restless legs syndrome (RLS) and periodic limb movements of sleep (PLMS) have been variably implicated in risk for cardiovascular disease (CVD), but there is lack of consensus on these relationships. We sought to assess subclinical CVD measures and RLS/PLMS in a large cohort to further evaluate these associations. The Emory Center for Health Discovery and Well Being cohort is composed of employed adults, with subclinical CVD measures including endothelial function (flow-mediated vasodilation), microvascular function (reactive hyperemia index, RHI), arterial stiffness (pulse wave velocity and augmentation index), and carotid intima-media thickness (cIMT)...
April 2024: Sleep and Biological Rhythms
https://read.qxmd.com/read/38514591/association-between-triglyceride-glucose-index-and-endothelial-dysfunction
#5
JOURNAL ARTICLE
Yan Li, Ming Yi, Xinyi Wang, Yinghua Zhang, Keling Xiao, Jin Si, Lijie Sun, Haoyu Zhang, Jinghao Sun, Zhaoli Liu, Jing Zhao, Xi Chu, Jing Li
BACKGROUND: Triglyceride-glucose (TyG) index, a simple surrogate marker for insulin resistance (IR), has been reported as an independent predictor of arterial structural damage and future cardiovascular events. The association between TyG index and endothelial dysfunction remains uncertain. OBJECTIVE: The purpose of this study was to investigate the association between TyG index and endothelial dysfunction. METHODS: Endothelial dysfunction was measured using flow-mediated dilation (FMD)...
March 21, 2024: Endocrine
https://read.qxmd.com/read/38513436/effects-of-alirocumab-on-endothelial-function-and-coronary-atherosclerosis-in-myocardial-infarction-a-pacman-ami-randomized-clinical-trial-substudy
#6
JOURNAL ARTICLE
Emrush Rexhaj, Sarah Bär, Rodrigo Soria, Yasushi Ueki, Jonas D Häner, Tatsuhiko Otsuka, Raminta Kavaliauskaite, George Cm Siontis, Stefan Stortecky, Hiroki Shibutani, David Spirk, Thomas Engstrøm, Irene Lang, Laura Morf, Maria Ambühl, Stephan Windecker, Sylvain Losdat, Konstantinos C Koskinas, Lorenz Räber
BACKGROUND AND AIMS: The effects of protein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on endothelial function as assessed by flow-mediated dilation (FMD) in patients with acute myocardial infarction (AMI) are unknown. Therefore, we aimed to investigate the effects of the PCSK9 inhibitor alirocumab added to high-intensity statin on FMD, and its association with coronary atherosclerosis in non-infarct related arteries using intracoronary intravascular ultrasound (IVUS), near-infrared spectroscopy (NIRS), and optical coherence tomography (OCT)...
March 6, 2024: Atherosclerosis
https://read.qxmd.com/read/38511256/augmented-mannose-binding-lectin-levels-in-primary-membranous-nephropathy-a-pilot-study
#7
JOURNAL ARTICLE
Deeksha Pal, Neeraj Inamdar, Prabhjot Kaur, Manphool Singhal, Anupam Lal, Ujjwal Gorsi, Ritambhra Nada, Harbir S Kohli, Vinod Kumar, Raja Ramachandran
There is evidence to suggest that M-type phospholipase A2 (PLA2R) antibodies activate the mannose-binding lectin (MBL) cascade, resulting in glomerular damage and proteinuria in patients with primary membranous nephropathy (PMN). Furthermore, there are few reports indicating that aberrant MBL activation is associated with endothelial dysfunction and accelerated atherosclerosis. While PMN is a common cause of adult nephrotic syndrome, and patients are at increased risk of cardiovascular disease (CVD), there is a lack of research that explores the factors that contribute to this condition...
March 21, 2024: Nephrology
https://read.qxmd.com/read/38497482/impact-of-secondary-amenorrhea-on-cardiovascular-disease-risk-in-physically-active-women-a-systematic-review-and-meta-analysis
#8
JOURNAL ARTICLE
Nicole L Tegg, Caitlynd Myburgh, Emma O'Donnell, Megan Kennedy, Colleen M Norris
BACKGROUND: Exercise-associated secondary amenorrhea results in estrogen deficiency, which may lead to dysfunction in estrogen's normal cardioprotective pathways. Estrogen may be essential in a woman's endothelial adaptations to exercise. The objective of this review was to assess the association between secondary amenorrhea in physically active women and cardiovascular disease (CVD) risk. METHODS AND RESULTS: A literature search was performed in January 2023 and updated in August 2023 of the Cumulative Index to Nursing and Allied Health Literature (EBSCOhost), Cochrane Library, Embase (Ovid), MEDLINE (Ovid), SPORTDiscus (EBSCOhost), and Scopus from inception to present with no date or language limitations...
March 19, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38491968/impact-of-insulin-induced-relative-hypoglycemia-on-vascular-insulin-sensitivity-and-central-hemodynamics-in-prediabetes
#9
JOURNAL ARTICLE
Daniel J Battillo, Mary-Margaret E Remchak, Ankit M Shah, Steven K Malin
CONTEXT: Relative hypoglycemia (RH) is linked to sympathetic responses that can alter vascular function in individuals with type 2 diabetes. However, less is known about the role of RH on hemodynamics or metabolic insulin sensitivity in prediabetes. OBJECTIVE: Determine if RH alters peripheral endothelial function or central hemodynamics to a greater extent in those with prediabetes (PD) versus normoglycemia (NG). METHODS: Seventy adults with obesity were classified using ADA criteria as PD (n=34 (28F); HbA1c=6...
March 16, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38487057/the-association-between-testosterone-and-vascular-function-in-reproductive-aged-females-with-chronic-kidney-disease
#10
JOURNAL ARTICLE
Nabilah Gulamhusein, Sofia B Ahmed, Jessalyn K Holodinsky, Marrissa Buchan, Ana Hernandez-Reyes, Susan Pyakurel, Darlene Y Sola, Milada Pajevic, Sandra M Dumanski
Cardiovascular disease is the leading cause of death in women, and women with chronic kidney disease (CKD) experience especially elevated risk. This study examined the association between testosterone and vascular function in 61 reproductive-aged females with CKD. Testosterone levels and measures of vascular function were assessed, including pulse wave velocity, aortic augmentation, flow-mediated dilation (FMD), and velocity time integral. Multivariable linear regression analyses assessed the relationship between testosterone and each measure of vascular function...
February 2024: CJC open
https://read.qxmd.com/read/38482571/peripheral-vascular-function-in-stroke-systematic-review-and-meta-analysis
#11
REVIEW
Bria L Bartsch, Emily M Hazen, Robert N Montgomery, Calvin Trieu, Amanda J Britton-Carpenter, Sandra A Billinger
UNLABELLED: Peripheral vascular dysfunction, measured as flow-mediated dilation (FMD), is present across all phases of stroke recovery and elevates risk for recurrent cardiovascular events. The objective of this systematic review and meta-analysis was to characterize baseline FMD in individuals post-stroke, with consideration for each phase of stroke recovery. METHODS: Three databases (PubMed, CINAHL, and Embase) were searched between January 1st , 2000 and October 12th , 2023 for studies that examined baseline FMD in stroke...
March 14, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38466890/cardiovascular-risk-in-women-with-nonclassical-congenital-adrenal-hyperplasia
#12
JOURNAL ARTICLE
Fernanda Cavalieri Costa, Larissa Garcia Gomes, Thais Martins de Lima, Luiz Aparecido Bortolotto, Valeria Hong, Renata Verardino, Manoel de Souza Rocha, Serli Kiyomi Nakao Ueda, Mirela Costa de Miranda, Heraldo Possolo de Souza, Ana Claudia Latronico, Berenice Bilharinho Mendonca, Tania A S S Bachega
CONTEXT: The outcomes related to cardiovascular risk (CVR) in patients with nonclassical form of congenital adrenal hyperplasia (NCAH) are unknown, especially those related to therapeutic options, including low doses of glucocorticoids (GCs) or oral contraceptive pills. OBJECTIVES: to analyze CVR by markers of atherosclerosis in females with nonclassical form according to therapeutic options. DESIGN AND SETTING: a cross-sectional study at a tertiary center...
March 11, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38463670/influence-of-cardiorespiratory-fitness-and-body-composition-on-resting-and-post-exercise-indices-of-vascular-health-in-young-adults
#13
JOURNAL ARTICLE
Rian Q Landers-Ramos, Kathleen Dondero, Ian Imery, Nicholas Reveille, Hannah A Zabriskie, Devon A Dobrosielski
Poor cardiorespiratory fitness may mediate vascular impairments at rest and following an acute bout of exercise in young healthy individuals. This study aimed to compare flow mediated dilation (FMD) and vascular augmentation index (AIx75) between young adults with low, moderate, and high levels of cardiorespiratory fitness before and after an acute bout of aerobic exercise. Forty-three participants (22 men; 21 women) between 18 and 29 years of age completed the study. Participants were classified into low, moderate, and high health-related cardiorespiratory fitness groups according to age- and sex-based relative maximal oxygen consumption (<mml:math xmlns:mml="https://www...
March 2024: Sports medicine and health science
https://read.qxmd.com/read/38452432/comparative-effects-of-glucose-lowering-agents-on-endothelial-function-and-arterial-stiffness-in-patients-with-type-2-diabetes-a-network-meta-analysis
#14
JOURNAL ARTICLE
Hayeon Kim, Cheol Ung Choi, Kiyon Rhew, Jiwon Park, Yejee Lim, Myeong Gyu Kim, Kyungim Kim
BACKGROUND AND AIMS: Despite accumulating evidence on the potential of glucose-lowering agents (GLAs) to prevent cardiovascular events, the comparative effects of GLAs on vascular function remain unclear. This study utilized validated indicators such as flow-mediated dilation (FMD; positive value favors) and pulse wave velocity (PWV; negative value favors) to uncover the comparative effects of GLAs on vascular function. METHODS: Randomized controlled trials (RCTs) comparing the effects of GLAs on FMD or PWV with placebo or other GLAs in patients with type 2 diabetes (T2DM) were searched through PubMed and Embase...
February 28, 2024: Atherosclerosis
https://read.qxmd.com/read/38449929/endothelial-dysfunction-in-children-with-nephrotic-syndrome-a-cross-sectional-study
#15
JOURNAL ARTICLE
Harapriya Das, Amit Satapathy, Joseph John, Manisha Kar, Sudipta Mohakud
Background Children with nephrotic syndrome (NS) have a higher risk of cardiovascular morbidity. Studies on the evaluation of arterial stiffness and endothelial function and its predictive risk factors in these children are limited. Objective The primary objective of the study was to determine arterial stiffness by measuring carotid intimal medial thickness, flow-mediated dilatation, and physiological parameters in children with nephrotic syndrome to predict the risk of premature atherosclerosis as compared to controls...
February 2024: Curēus
https://read.qxmd.com/read/38449487/renal-arteriovenous-malformation-treated-using-glue-embolization-under-inflow-and-outflow-control-by-balloon-occlusion
#16
Tensei Suzuki, Hidenori Yamaguchi, Mitsuaki Kojima, Toshiya Kariyasu, Raira Nakamoto, Makiko Nishikawa, Haruhiko Machida, Tomohisa Shoko
A 45-year-old female presented with gross hematuria. Right renal arteriovenous malformation on abdominal contrast-enhanced computed tomography necessitated urgent transcatheter arterial embolization. Right renal digital subtraction angiography revealed a single tortuous and dilated vessel converging to an aneurysmal dilated vein. To selectively embolize the malformation, we closed the arterial side with a microballoon and attempted glue embolization; filling occurred unexpectedly early, and another balloon on the vein side helped control the renal vein blood flow...
May 2024: Radiology Case Reports
https://read.qxmd.com/read/38447552/relationship-of-warfarin-and-apixaban-with-vascular-function-in-patients-with-atrial-fibrillation
#17
JOURNAL ARTICLE
Rehan T Junejo, Dhiraj Gupta, Richard L Snowdon, Gregory Y H Lip, James P Fisher
INTRODUCTION: Atrial fibrillation (AF) is associated with endothelial damage/dysfunction. Herein, we tested the hypothesis that brachial artery flow-mediated dilation (FMD) is superior in AF patients taking apixaban compared to warfarin. METHODS: AF patients on apixaban (n = 46; 67 [7] years; mean [standard deviation]; 15 women) and warfarin (n = 27; 73 [9] years (p &lt; 0.01); 11 women) were recruited. Duplex Doppler ultrasound imaging was undertaken during baseline (2 min), cuff inflation (5 min), and following cuff deflation (3 min)...
March 6, 2024: Journal of Vascular Research
https://read.qxmd.com/read/38442044/power-doppler-ultrasonic-imaging-of-peripheral-perfusion-in-diabetic-mice
#18
JOURNAL ARTICLE
Somaye Babaei, Lawrence W Dobrucki, Michael F Insana
OBJECTIVE: We explored the capabilities of power-Doppler ultrasonic (PD-US) imaging without contrast enhancement for monitoring changes in muscle perfusion over time. METHODS: Ischemic recovery was observed in healthy and type II diabetic male and female mice with and without exercise. In separate studies, perfusion was measured during and after 5-min ischemic periods and during four-week recovery periods following irreversible femoral ligation. A goal was to assess how well PD-US estimates tracked the diabetic-related changes in endothelial function that influenced perfusion...
March 5, 2024: IEEE Transactions on Bio-medical Engineering
https://read.qxmd.com/read/38430616/the-effect-of-dietary-interventions-or-patterns-on-the-cardiometabolic-health-of-individuals-treated-with-androgen-deprivation-therapy-for-prostate-cancer-a-systematic-review
#19
REVIEW
Hattie Hester Wright, Meegan Anne Walker, Suzanne Broadbent, Corey Linton, Jacob Joseph Keech, Karina Tirsvad Rune, Cindy Lynne Davis, Michelle Morris, Anao Zhang, Robert Usher Newton, Skye Marshall
Prostate cancer survivors treated with androgen deprivation therapy may be at increased risk of cardiovascular disease. Dietary recommendations for the prevention and/or management of cardiovascular disease for these individuals are lacking. This review synthesizes the evidence on the effect of dietary interventions on cardiometabolic biomarkers and cardiovascular disease risk in prostate cancer survivors receiving androgen deprivation therapy. A systematic review was conducted across PubMed, CINAHL, Embase, and Cochrane CENTRAL...
February 20, 2024: Maturitas
https://read.qxmd.com/read/38406844/brain-atrophy-reduced-cerebral-perfusion-arterial-stiffening-and-wall-thickening-with-ageing-coincide-with-stimulus-specific-changes-in-fmri-bold-responses
#20
JOURNAL ARTICLE
Nicole S Coverdale, Allen A Champagne, Matti Douglas Allen, Joshua C Tremblay, Tarrah S Ethier, Juan Fernandez-Ruiz, Rory A Marshall, Rebecca E K MacPherson, Kyra E Pyke, Douglas J Cook, T Dylan Olver
The aim of this study was to investigate how aging affects blood flow and structure of the brain. It was hypothesized older individuals would have lower grey matter volume (GMV), resting cerebral blood flow (CBF0 ), and depressed responses to iso-metabolic and neuro-metabolic stimuli. Additionally, increased carotid-femoral pulse wave velocity (PWV), carotid intima-media thickness (IMT), and decreased brachial flow-mediated dilation (FMD) would be associated with lower CBF0 , cerebrovascular reactivity (CVR) and GMV...
February 26, 2024: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
keyword
keyword
8906
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.