keyword
https://read.qxmd.com/read/38493446/contouring-aid-tools-in-radiotherapy-smoothing-the-false-friend
#1
JOURNAL ARTICLE
Jordi Marruecos Querol, Diego Jurado-Bruggeman, Anna Lopez-Vidal, Ricard Mesía Nin, Jordi Rubió-Casadevall, Maria Buxó, Aranzazu Eraso Urien
OBJECTIVE: Contouring accuracy is critical in modern radiotherapy. Several tools are available to assist clinicians in this task. This study aims to evaluate the performance of the smoothing tool in the ARIA system to obtain more consistent volumes. METHODS: Eleven different geometric shapes were delineated in ARIA v15.6 (Sphere, Cube, Square Prism, Six-Pointed Star Prism, Arrow Prism, And Cylinder and the respective volumes at 45° of axis deviation (_45)) in 1, 3, 5, 7, and 10 cm side or diameter each...
March 17, 2024: Clinical & Translational Oncology
https://read.qxmd.com/read/38493080/effectiveness-of-human-immunodeficiency-virus-prevention-strategies-by-mapping-the-geographic-dispersion-pattern-of-human-immunodeficiency-virus-prevalence-in-nanning-china
#2
JOURNAL ARTICLE
Ping Cen, Guo Xu, Jianxun Wu, Jiao Qin, Jinfeng He, Xiaofang Deng, Xi Yang, Peng Lu, Mengni Nong, Junjun Jiang, Li Ye, Hongyang Tang, Bingyu Liang, Hao Liang
BACKGROUND: The Guangxi government initiated two rounds of the Guangxi AIDS Conquering Project (GACP) in 2010 (Phase I) and 2015 (Phase II) to control human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) epidemics. However, the effectiveness of GACP in HIV prevention and treatment has rarely been reported. This study aimed to assess the effectiveness of the GACP implemented in Guangxi, China and provide data for strategy and praxis improvements to achieve Joint United Nations Programme on HIV/AIDS (UNAIDS) 95-95 targets...
March 16, 2024: BMC Public Health
https://read.qxmd.com/read/38492834/bycatch-and-pollution-are-the-main-threats-for-burmeister-s-porpoises-inhabiting-a-high-industrialized-bay-in-the-humboldt-current-system
#3
JOURNAL ARTICLE
Ana M García-Cegarra, Anna Hall, Emma Martínez-López
Pollution and bycatch are two of the main threats for cetaceans worldwide. These threats are exacerbated for nearshore species particularly for those in regions with intense industrial and fishing activities. Burmeister's porpoise is endemic to South America, has a Near Threatened conservation status because of long-term mortality in fisheries. Burmeister's porpoise occur in Mejillones Bay, northern Chile, a hot spot for heavy metals pollution from the mining industry and an intense industrial and artisanal purse-seine fishing area...
March 14, 2024: Environmental Research
https://read.qxmd.com/read/38492660/collateral-round-ligament-arterial-supply-of-placenta-accreta-spectrum-and-considerations-for-prophylactic-balloon-occlusion-catheter-placement
#4
JOURNAL ARTICLE
Matthew Lukies, Luke Toh Han Wei, Sivanathan Chandramohan
Internal iliac artery (IIA) balloon occlusion catheters have been commonly inserted to decrease the risk of post-partum hemorrhage in placenta accreta spectrum disorders, however, there has been mixed success in clinical trials. Placement of an infra-renal aortic balloon has shown more consistent efficacy in recent studies. A possible reason for this is collateral arterial supply to the placenta from external iliac artery branches. Retrospective chart review was conducted of angiography images during prophylactic IIA balloon occlusion catheter insertion over a 7-year period...
March 14, 2024: Journal of Vascular and Interventional Radiology: JVIR
https://read.qxmd.com/read/38492630/development-and-testing-of-step-error-and-event-frameworks-to-evaluate-technical-performance-in-peripheral-endovascular-interventions
#5
JOURNAL ARTICLE
Gilles Soenens, Lauren Gorden, Bart Doyen, Mark Wheatcroft, Charles de Mestral, Vanessa Palter, Isabelle Van Herzeele
OBJECTIVE: Tools for endovascular performance assessment are necessary in competency based education. This study aimed to develop and test a detailed analysis tool to assess steps, errors, and events in peripheral endovascular interventions (PVI). METHODS: A modified Delphi consensus was used to identify steps, errors, and events in iliac-femoral-popliteal endovascular interventions. International experts in vascular surgery, interventional radiology, cardiology, and angiology were identified, based on their scientific track record...
March 14, 2024: European Journal of Vascular and Endovascular Surgery
https://read.qxmd.com/read/38492408/categorizing-digital-data-collection-and-intervention-tools-in-health-and-wellbeing-living-lab-settings-a-modified-delphi-study
#6
JOURNAL ARTICLE
Despoina Petsani, Teemu Santonen, Beatriz Merino-Barbancho, Gorka Epelde, Panagiotis Bamidis, Evdokimos Konstantinidis
BACKGROUND: Health and Wellbeing Living Labs are a valuable research infrastructure for exploring innovative solutions to tackle complex healthcare challenges and promote overall wellbeing. A knowledge gap exists in categorizing and understanding the types of ICT tools and technical devices employed by Living Labs. AIM: Define a comprehensive taxonomy that effectively categorizes and organizes the digital data collection and intervention tools employed in Health and Wellbeing Living Lab research studies...
March 10, 2024: International Journal of Medical Informatics
https://read.qxmd.com/read/38491928/evolution-of-wing-shape-in-geometrid-moths-phylogenetic-effects-dominate-over-ecology
#7
JOURNAL ARTICLE
Kadri Ude, Erki Õunap, Ants Kaasik, Robert B Davis, Juhan Javoiš, Vineesh Nedumpally, Stenio I A Foerster, Toomas Tammaru
Locomotory performance is an important determinant of fitness in most animals, including flying insects. Strong selective pressures on wing morphology are therefore expected. Previous studies on wing shape in Lepidoptera have found some support for hypotheses relating wing shape to environment-specific selective pressures on aerodynamic performance. Here, we present a phylogenetic comparative study on wing shape in the lepidopteran family Geometridae, covering 374 species of the northern European fauna. We focused on eleven wing traits including aspect ratio, wing roundness, and the pointedness of the apex, as well as the ratio of forewing and hindwing areas...
March 16, 2024: Journal of Evolutionary Biology
https://read.qxmd.com/read/38491894/changing-roles-in-global-health-governance-following-covid-19
#8
JOURNAL ARTICLE
Wafa Abu El Kheir-Mataria, Hassan El-Fawal, Sungsoo Chun
BACKGROUND: The Global Health Governance (GHG) response to the COVID-19 pandemic has been criticized, particularly regarding vaccine management, and changes in the roles of GHG actors have been recommended. AIM: To investigate the perception of experts regarding changes in the roles of different GHG actors following the COVID-19 pandemic. METHODS: This study used a 3-round Delphi survey to collect data from 30 global health experts between May and December 2022...
February 25, 2024: Eastern Mediterranean Health Journal
https://read.qxmd.com/read/38491849/structure-of-the-oral-tentacles-of-early-ontogeny-stage-in-brachiopod-hemithiris-psittacea-rhynchonelliformea-rhynchonellida
#9
JOURNAL ARTICLE
Tatyana Valerievna Kuzmina, Elena Nikolaevna Temereva
Brachiopods have the most complex lophophore in comparison with other lophophorates, i.e., phoronids and bryozoans. However, at early ontogenetic stages, brachiopods have a lophophore of simple morphology, which consists of the oral tentacles. Data on the ultrastructure of the oral tentacles is mostly missing. Nonetheless, it has recently been suggested that the structure of oral tentacles is ancestral for all lophophorates in general, and for brachiopods in particular. The fine structure of the oral tentacles in the brachiopod Hemithiris psittacea is studied using light microscopy, transmission and scanning electron microscopy, cytochemistry and confocal laser scanning microscopy...
April 2024: Journal of Morphology
https://read.qxmd.com/read/38491830/common-data-elements-for-arthrogryposis-multiplex-congenita-an-international-framework
#10
JOURNAL ARTICLE
Shahrzad Nematollahi, Klaus Dieterich, Isabel Filges, Johanna I P De Vries, Harold Van Bosse, Daniel Natera-De Benito, Judith G Hall, Bonita Sawatzky, Tanya Bedard, Victoria Castillo Sanchez, Carolina Navalon-Martinez, Tony Pan, Coleman Hilton, Noémi Dahan-Oliel
AIM: To facilitate multisite studies and international clinical research, this study aimed to identify consensus-based, standardized common data elements (CDEs) for arthrogryposis multiplex congenita (AMC). METHOD: A mixed-methods study comprising of several focus group discussions and three rounds of modified Delphi surveys to achieve consensus using two tiered-rating scales were conducted. RESULTS: Overall, 45 clinical experts and adults with lived experience (including 12 members of an AMC consortium) participated in this study from 11 countries in North America, Europe, and Australia...
March 16, 2024: Developmental Medicine and Child Neurology
https://read.qxmd.com/read/38491174/transforming-post-pandemic-cancer-services
#11
REVIEW
Thomas Round, Lakshman Sethuraman, Mark Ashworth, Arnie Purushotham
This paper outlines the impact of the COVID-19 pandemic on cancer services in the UK including screening, symptomatic diagnosis, treatment pathways and projections on clinical outcomes as a result of these care disruptions. A restoration of cancer services to pre-pandemic levels is not likely to mitigate this adverse impact, particularly with an ageing population and increased cancer burden. New cancer cases are projected to rise to over 500,000 per year by 2035, with over 4 million people living with and beyond cancer...
March 15, 2024: British Journal of Cancer
https://read.qxmd.com/read/38490856/prostate-cancers-in-the-prostate-specific-antigen-interval-of-1-8-3-ng-ml-results-from-the-g%C3%A3-teborg-2-prostate-cancer-screening-trial
#12
JOURNAL ARTICLE
Fredrik Möller, Marianne Månsson, Jonas Wallström, Mikael Hellström, Jonas Hugosson, Rebecka Arnsrud Godtman
BACKGROUND: Magnetic resonance imaging (MRI) and targeted biopsies reduce overdiagnosis of prostate cancer (PC). It is uncertain how this strategy performs for low prostate-specific antigen (PSA) levels. OBJECTIVE: To investigate the Prostate Imaging Reporting and Data System (PI-RADS) distribution, frequency, and characteristics of screen-detected PC with PSA of 1.8-<3 ng/ml and 3-<10 ng/ml. DESIGN, SETTING, AND PARTICIPANTS: In the population-based Göteborg-2 screening study, 17974 men choose to participate by having a PSA test (2015-2020)...
March 14, 2024: European Urology
https://read.qxmd.com/read/38490837/virtual-burn-care-friend-or-foe-a-systematic-review
#13
REVIEW
Eli Mondor, Jaymie Barnabe, Ella Marie Robyn Laguan, Claudia Malic
INTRODUCTION: Evidence on the impact of virtual care for patients with burn injuries is variable. This review aims to evaluate its use in remote assessment, rounding, and follow-up through outcomes of efficacy, usability, costs, satisfaction, clinical outcomes, impacts on triage and other benefits/drawbacks. METHODS: A PRISMA-compliant qualitative systematic review (PROSPERO CRD42021267787) was conducted in four databases and the grey literature for primary research published between 01/01/2010 and 12/31/2020...
February 28, 2024: Burns
https://read.qxmd.com/read/38490661/defining-acceptable-data-collection-and-reuse-standards-for-queer-artificial-intelligence-research-in-mental-health-protocol-for-the-online-parqair-mh-delphi-study
#14
JOURNAL ARTICLE
Dan W Joyce, Andrey Kormilitzin, Julia Hamer-Hunt, Kevin R McKee, Nenad Tomasev
INTRODUCTION: For artificial intelligence (AI) to help improve mental healthcare, the design of data-driven technologies needs to be fair, safe, and inclusive. Participatory design can play a critical role in empowering marginalised communities to take an active role in constructing research agendas and outputs. Given the unmet needs of the LGBTQI+ (Lesbian, Gay, Bisexual, Transgender, Queer and Intersex) community in mental healthcare, there is a pressing need for participatory research to include a range of diverse queer perspectives on issues of data collection and use (in routine clinical care as well as for research) as well as AI design...
March 15, 2024: BMJ Open
https://read.qxmd.com/read/38490544/the-association-between-teat-shape-and-bimodal-milk-ejection-in-holstein-dairy-cows
#15
JOURNAL ARTICLE
M Wieland, M E Spellman, H Somula, A Singh
Our objectives were to investigate the association of teat shape with (1) bimodality (2) incremental milk flow rates (average flow rates during the first 15 s, 15-30 s, 30-60 s, and 60-120 s of milking), and (3) peak milk flow rate in Holstein dairy cows milked 3 times per day. In this prospective cohort study, we analyzed 220,928 milking observations that were collected from 2,520 cows from a single dairy herd over a period of 31 d. Teat shape was visually assessed and classified into 1 of 4 categories as follows: (1) triangular barrel and pointed teat end (TP), (2) square barrel and round teat end (SR), (3) square barrel, round teat end, and flat in the area of the teat orifice (SRF), and (4) square barrel and flat teat end (SF)...
March 13, 2024: Journal of Dairy Science
https://read.qxmd.com/read/38490078/extending-the-grading-of-recommendations-assessment-development-and-evaluation-grade-in-traditional-chinese-medicine-tcm-the-grade-tcm
#16
JOURNAL ARTICLE
Qin-Wei Fu, Yang Liu, Shu-Cheng Chen, Lan-Zhi Zhang, Wei-Ting Liu, Zhi-Qing Liu, Ying Liu, Yan Xie, Li Fu, Min Liu, Da-Zheng Zhang, Sha-Sha Yang, Fu-Bin Zhang, He-Yin Huang, Juan Zhong, Kai-Yun Pang, Yong-Na Chen, Ye-Peng Yang, Meng-Lin Dai, Shu-Yun Liu, Shi-Peng Zhang, Feng Xiang, Mi Tang, Pei-Jia Li, Cai-Shan Fang, Qin-Xiu Zhang, Wing-Fai Yeung, Xin-Rong Li
AIM: To extend and form the "Grading of Recommendations Assessment, Development and Evaluation in Traditional Chinese Medicine" (GRADE-TCM). METHODS: Methodologies were systematically reviewed and analyzed concerning evidence-based TCM guidelines worldwide. A survey questionnaire was developed based on the literature review and open-end expert interviews. Then, we performed expert consensus, discussion meeting, opinion collection, external examination, and the GRADE-TCM was formed eventually...
February 27, 2024: Phytomedicine
https://read.qxmd.com/read/38489997/synthesis-and-biological-activity-of-11-oxygenated-and-heterocyclic-estrone-analogs-in-pancreatic-cancer-monolayers-and-3d-spheroids
#17
JOURNAL ARTICLE
Khaled Alseud, Trevor Ostlund, Mikhail Durymanov, Joshua Reineke, Fathi Halaweish
Pancreatic Ductal Adenocarcinoma (PDAC), representing over 90 % of pancreatic cancer diagnoses, is an aggressive disease with survivability among the worst of all cancers due to its difficulty in detection and its high metastatic properties. Current therapies for PDAC show limited success at extending life expectancies, primarily due to cancer resistance and lack of patient-specific targeted therapies. This work highlights the design and evaluation of estrone-derived analogs with both heterocyclic side-chain functionality and 11-oxygenated functionality for use in pancreatic cancer...
March 5, 2024: Bioorganic & Medicinal Chemistry
https://read.qxmd.com/read/38489921/comparing-region-of-interest-selection-and-whole-field-analysis-for-measurement-of-ciliary-beat-frequency-in-high-speed-video-analysis
#18
JOURNAL ARTICLE
Miki Abo, Kousuke Imamura, Shigekuni Hosogi, Takafumi Kobayashi, Yoshihiro Takeda, Kazumasa Kase, Hayato Koba, Satoshi Watanabe, Noriyuki Ohkura, Johsuke Hara, Seiji Yano
BACKGROUND: Ciliary beat frequency (CBF) is crucial in mucociliary clearance. High-speed video analysis (HSVA) is commonly used to measure CBF but lacks standardization. We compared visual observation and computer-assisted calculation using fast Fourier transformation (FFT) in freshly collected bronchial ciliary epithelial cells and cultured cells. METHODS: Bronchial epithelial cells were obtained from 12 patients who required bronchoscopic examination. Eighty-five videos of ciliary movement of freshly collected and cultured cells were recorded and used to calculate CBF using manual observation, region of interest (ROI) selection, and whole-field analysis...
March 14, 2024: Respiratory Investigation
https://read.qxmd.com/read/38489481/quality-and-patient-safety-metrics-developing-a-structured-program-for-improving-patient-care-in-the-department-of-medicine-at-the-ottawa-hospital
#19
JOURNAL ARTICLE
Delvina Hasimja-Saraqini, Kylie McNeill, Hanna Kuk, Alan J Forster, Philip S Wells, Samantha Hamilton, Ed Gannon, Lisa M Mielniczuk
PROBLEM: Despite increasing recognition of the importance of quality and patient safety in academic medicine, challenges remain with ensuring physician participation in quality assurance and quality improvement efforts, such as lack of compensation and enabling resources. An organizational culture that includes physician leadership and a supportive infrastructure is needed to encourage physician backing of quality and patient safety initiatives. APPROACH: The authors describe the development of a robust quality and patient safety program in the Department of Medicine at The Ottawa Hospital over the past 7 years and highlight how the department changed its organizational culture by prioritizing quality and patient safety and establishing the necessary infrastructure to support this program...
March 15, 2024: Academic Medicine
https://read.qxmd.com/read/38488847/estimation-of-the-population-size-of-street-and-venue-based-female-sex-workers-and-sexually-exploited-minors-in-rwanda-in-2022-3-source-capture-recapture
#20
JOURNAL ARTICLE
Elysee Tuyishime, Eric Remera, Catherine Kayitesi, Samuel Malamba, Beata Sangwayire, Ignace Habimana Kabano, Horacio Ruisenor-Escudero, Tom Oluoch, Angela Unna Chukwu
BACKGROUND: HIV surveillance among key populations is a priority in all epidemic settings. Female sex workers (FSWs) globally as well as in Rwanda are disproportionately affected by the HIV epidemic; hence, the Rwanda HIV and AIDS National Strategic Plan (2018-2024) has adopted regular surveillance of population size estimation (PSE) of FSWs every 2-3 years. OBJECTIVE: We aimed at estimating, for the fourth time, the population size of street- and venue-based FSWs and sexually exploited minors aged ≥15 years in Rwanda...
March 15, 2024: JMIR Public Health and Surveillance
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