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https://www.readbyqxmd.com/read/28096440/tnf-signaling-in-peritoneal-mesothelial-cells-pivotal-role-of-cflipl
#1
Willie M Lüdemann, Danijela Heide, Lars Kihm, Martin Zeier, Peter Scheurich, Vedat Schwenger, Julia Ranzinger
♦ Background: Peritoneal dialysis (PD) coincides with high concentrations of proinflammatory cytokines, such as tumor necrosis factor (TNF), in the peritoneal cavity. During treatment, chronic inflammatory processes lead to damage of the peritoneal membrane and a subsequent ultrafiltration failure. Human peritoneal mesothelial cells (HPMCs) play a central role as mediators and targets of PD-related inflammatory changes. Although TNF Receptor 1 (TNFR1) is expressed in high numbers on the cells, TNF-induced apoptosis is inhibited...
January 17, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28079561/-single-checked-patient-group-directions-during-initial-nurse-assessment-within-paediatric-emergency-departments-of-the-uk-and-ireland
#2
Chris K Bird, Anthony G Sinclair, Stuart Hartshorn
OBJECTIVE: Double checking medications at initial assessment within paediatric emergency departments (EDs) has the potential to delay patient flow, and doubt has been cast on the efficacy of double checking in all but high-risk medications. We aimed to benchmark current practice for the use of Patient Group Direction (PGD) medications at initial assessment in EDs within the Paediatric Emergency Research UK and Ireland (PERUKI) network, with a focus on the use of 'single-checker' PGDs...
January 10, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/28079422/examining-an-alcohol-health-worker-service-s-patient-coverage
#3
Andrew Papworth, Charlie Lloyd, Sarah Baker
Alcohol health workers (AHWs) have been found to be effective at reducing alcohol-related hospital admissions, but there is still a paucity of evidence in keys areas. This was the first study to investigate what percentage of patients referred to an AHW service by alcohol screening tools are actually seen by the AHWs. The study-based in a large teaching hospital in the north of England-also investigated the impact of social deprivation on service usage. Research data came from a patient database and semi-structured interviews with AHWs...
January 12, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28074564/sustaining-sbirt-in-the-wild-simulating-revenues-and-costs-for-screening-brief-intervention-and-referral-to-treatment-programs
#4
Alexander J Cowell, William N Dowd, Michael J Mills, Jesse M Hinde, Jeremy W Bray
AIMS: To examine the conditions under which Screening, Brief Intervention and Referral to Treatment (SBIRT) programs can be sustained by health insurance payments. DESIGN: A mathematical model was used to estimate the number of patients needed for revenues to exceed costs. SETTING: Three medical settings in the United States were examined: in-patient, out-patient and emergency department. Components of SBIRT were delivered by combinations of health-care practitioners (generalists) and behavioral health specialists...
February 2017: Addiction
https://www.readbyqxmd.com/read/28072666/outcomes-from-referrals-and-unscheduled-visits-from-community-emergency-departments-to-a-regional-pediatric-emergency-department-in-canada
#5
Ethan Reiner, Ardalan Ahmadi, Eric Grafstein, Quynh Doan
OBJECTIVES: Existing pediatric literature describing repeat visits to the emergency department (ED) for the same medical complaint has yet to report on patient flow patterns from general EDs (GEDs) to a pediatric ED (PED). We sought to characterize the population of patients who are treated in a GED and subsequently present to a PED for further care. METHODS: We conducted a retrospective cohort study reviewing all pediatric visits (age < 17 y) at 5 GEDs in Vancouver...
January 9, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28061896/improving-patient-flow-of-people-with-rheumatoid-arthritis-has-the-potential-to-simultaneously-improve-health-outcomes-and-reduce-direct-costs
#6
R Puchner, R Hochreiter, H Pieringer, A Vavrovsky
BACKGROUND: In our current economic climate of scarce resources there is a lot of debate around the best - and most efficient - way of delivering care, which points patients towards the right physician at the earliest opportunity. The aim of the study was to assess whether an improvement in the interdisciplinary management of rheumatoid arthritis (RA) has the potential to simultaneously improve health outcomes and reduce costs. METHODS: In a first step, we modelled the ways which lead patients with RA to the correct diagnosis, and the relevant specialist, respectively...
January 7, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28060232/a-dedicated-orthopaedic-trauma-operating-room-improves-efficiency-at-a-pediatric-center
#7
Christopher M Brusalis, Apurva S Shah, Xianqun Luan, Meaghan K Lutts, Wudbhav N Sankar
BACKGROUND: Dedicated orthopaedic trauma operating rooms have improved operating room efficiency, physician schedules, and patient outcomes in adult populations. The purpose of this study was to determine if a dedicated orthopaedic trauma operating room was associated with improved patient flow and cost savings at a level-I pediatric trauma center. METHODS: A retrospective analysis was performed for two 3-year intervals before and after implementation of a weekday, unbooked operating room reserved for orthopaedic trauma cases...
January 4, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28050715/workflow-lexicons-in-healthcare-validation-of-the-swim-lexicon
#8
Chris Meenan, Bradley Erickson, Nancy Knight, Jewel Fossett, Elizabeth Olsen, Prerna Mohod, Joseph Chen, Steve G Langer
For clinical departments seeking to successfully navigate the challenges of modern health reform, obtaining access to operational and clinical data to establish and sustain goals for improving quality is essential. More broadly, health delivery organizations are also seeking to understand performance across multiple facilities and often across multiple electronic medical record (EMR) systems. Interpreting operational data across multiple vendor systems can be challenging, as various manufacturers may describe different departmental workflow steps in different ways and sometimes even within a single vendor's installed customer base...
January 3, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28048777/mo-e-brb-00-panel-discussion-sbrt-srs-case-studies-lung
#9
Stanley Benedict
: In this interactive session, lung SBRT patient cases will be presented to highlight real-world considerations for ensuring safe and accurate treatment delivery. An expert panel of speakers will discuss challenges specific to lung SBRT including patient selection, patient immobilization techniques, 4D CT simulation and respiratory motion management, target delineation for treatment planning, online treatment alignment, and established prescription regimens and OAR dose limits. Practical examples of cases, including the patient flow thought the clinical process are presented and audience participation will be encouraged...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048757/mo-e-brb-01-panel-member
#10
S Benedict
: In this interactive session, lung SBRT patient cases will be presented to highlight real-world considerations for ensuring safe and accurate treatment delivery. An expert panel of speakers will discuss challenges specific to lung SBRT including patient selection, patient immobilization techniques, 4D CT simulation and respiratory motion management, target delineation for treatment planning, online treatment alignment, and established prescription regimens and OAR dose limits. Practical examples of cases, including the patient flow thought the clinical process are presented and audience participation will be encouraged...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048099/mo-e-brb-02-panel-member
#11
J Larner
: In this interactive session, lung SBRT patient cases will be presented to highlight real-world considerations for ensuring safe and accurate treatment delivery. An expert panel of speakers will discuss challenges specific to lung SBRT including patient selection, patient immobilization techniques, 4D CT simulation and respiratory motion management, target delineation for treatment planning, online treatment alignment, and established prescription regimens and OAR dose limits. Practical examples of cases, including the patient flow thought the clinical process are presented and audience participation will be encouraged...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047441/mo-e-brb-03-panel-member
#12
B Salter
: In this interactive session, lung SBRT patient cases will be presented to highlight real-world considerations for ensuring safe and accurate treatment delivery. An expert panel of speakers will discuss challenges specific to lung SBRT including patient selection, patient immobilization techniques, 4D CT simulation and respiratory motion management, target delineation for treatment planning, online treatment alignment, and established prescription regimens and OAR dose limits. Practical examples of cases, including the patient flow thought the clinical process are presented and audience participation will be encouraged...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045348/the-impact-of-increasing-staff-resources-on-patient-flow-in-a-psychiatric-emergency-service
#13
Lara Chepenik, Edieal Pinker
OBJECTIVE: The study illustrates the use of approaches based on queuing theory to understand bottlenecks in patient flow. A queuing simulation was used to predict the potential benefits of additional clinical personnel on patient flow through a psychiatric emergency service (PES). METHODS: A discrete-event simulation model was calibrated on the basis of two months of data collected in a PES. This model examined the effects of adding between .5 (half-time) and three additional providers to the 8 a...
January 3, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28012828/can-patient-variables-measured-on-arrival-to-the-emergency-department-predict-disposition-in-medium-acuity-patients
#14
John P Riordan, Wayne L Dell, James T Patrie
BACKGROUND: Emergency department crowding has led to innovative "front end" care models to safely and efficiently care for medium and lower acuity patients. In the United States, most treatment algorithms rely on the emergency severity index (ESI) triage tool to sort patients. However, there are no objective criteria used to differentiate ESI 3 patients. OBJECTIVE: We seek to derive and validate a model capable of predicting patient discharge disposition (DD) using variables present on arrival to the emergency department for ESI 3 patients...
December 21, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28009102/feeling-the-heat-using-hourly-emergency-activity-tracking-to-demonstrate-a-novel-method-of-describing-activity-and-patient-flow
#15
Kendall J Bein, Saartje Berendsen Russell, David Muscatello, Dane Chalkley, Rebecca Ivers, Michael M Dinh
OBJECTIVE: The objective of the present study is to demonstrate a novel method of mapping ED activity to analyse patterns presentations, occupancy and performance trends. METHODS: This was a retrospective, descriptive analysis of de-identified and linked ED presentations across NSW, Australia, over five calendar years, 2010-2014. It was undertaken as part of the Demand for Emergency Services Trend in Years 2010-2014 (DESTINY) study. The DESTINY project analysed 10...
December 23, 2016: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/27998879/using-patient-flow-information-to-determine-risk-of-hospital-presentation-protocol-for-a-proof-of-concept-study
#16
Christopher M Pearce, Adam McLeod, Jon Patrick, Douglas Boyle, Marianne Shearer, Paula Eustace, Mary Catherine Pearce
BACKGROUND: Every day, patients are admitted to the hospital with conditions that could have been effectively managed in the primary care sector. These admissions are expensive and in many cases are possible to avoid if early intervention occurs. General practitioners are in the best position to identify those at risk of imminent hospital presentation and admission; however, it is not always possible for all the factors to be considered. A lack of shared information contributes significantly to the challenge of understanding a patient's full medical history...
December 20, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27970701/utilisation-of-survival-outcomes-data-to-forecast-economic-impact-of-pricing-and-market-access-scenarios-in-a-multi-indication-patient-flow-models
#17
P Sogokon, M Hunt, J Kjeldgaard-Pedersen, G Furneri, M Chalmers
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27942343/effects-of-a-general-practitioner-cooperative-co-located-with-an-emergency-department-on-patient-throughput
#18
Michiel J van Veelen, Crispijn L van den Brand, Resi Reijnen, M Christien van der Linden
BACKGROUND: In 2013 a General Practitioner Cooperative (GPC) was introduced at the Emergency Department (ED) of our hospital. One of the aims of this co-located GPC was to improve throughput of the remaining patients at the ED. To determine the change in patient flow, we assessed the number of self-referrals, redirection of self-referrals to the GPC and back to the ED, as well as ward and ICU admission rates and length of stay of the remaining ED population. METHODS: We conducted a four months' pre-post comparison before and after the implementation of a co-located GPC with an urban ED in the Netherlands...
2016: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27940683/modification-of-an-established-pediatric-asthma-pathway-improves-evidence-based-efficient-care
#19
Lori Rutman, Robert C Atkins, Russell Migita, Jeffrey Foti, Suzanne Spencer, K Casey Lion, Davene R Wright, Michael G Leu, Chuan Zhou, Rita Mangione-Smith
OBJECTIVE: In September 2011, an established pediatric asthma pathway at a tertiary care children's hospital underwent significant revision. Modifications included simplification of the visual layout, addition of evidence-based recommendations regarding medication use, and implementation of standardized admission criteria. The objective of this study was to determine the impact of the modified asthma pathway on pathway adherence, percentage of patients receiving evidence-based care, length of stay, and cost...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27919244/surgical-antibiotic-prophylaxis-in-children-a-mixed-method-study-on-healthcare-professionals-attitudes
#20
Angela Giusti, Stefania Spila Alegiani, Marta Luisa Ciofi Degli Atti, Sofia Colaceci, Roberto Raschetti, Pasquale Arace, Raffaele Spiazzi, Massimiliano Raponi
BACKGROUND: Qualitative and quantitative research investigating determinants of adherence to clinical guidelines (GLs) on surgical antibiotic prophylaxis (SAP) are scarce. We conducted a mixed-method study aimed at investigating barriers and at describing attitudes of healthcare professionals (HCPs) regarding SAP in three Italian children's hospitals. METHODS: The study comprised two sequential phases: 1) collection of qualitative data through focus groups; 2) conduction of a survey on HCPs attitudes towards SAP...
December 5, 2016: BMC Pediatrics
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