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https://www.readbyqxmd.com/read/28225072/copper-treatment-during-storage-reduces-phytophthora-and-halophytophthora-infection-of-zostera-marina-seeds-used-for-restoration
#1
Laura L Govers, Els M van der Zee, Johan P Meffert, Patricia C J van Rijswick, Willem A Man In 't Veld, Jannes H T Heusinkveld, Tjisse van der Heide
Restoration is increasingly considered an essential tool to halt and reverse the rapid decline of vital coastal ecosystems dominated by habitat-forming foundation species such as seagrasses. However, two recently discovered pathogens of marine plants, Phytophthora gemini and Halophytophthora sp. Zostera, can seriously hamper restoration efforts by dramatically reducing seed germination. Here, we report on a novel method that strongly reduces Phytophthora and Halophytophthora infection of eelgrass (Zostera marina) seeds...
February 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28208794/qsrr-modeling-for-metabolite-standards-analyzed-by-two-different-chromatographic-columns-using-multiple-linear-regression
#2
Chrysostomi Zisi, Ioannis Sampsonidis, Stella Fasoula, Konstantinos Papachristos, Michael Witting, Helen G Gika, Panagiotis Nikitas, Adriani Pappa-Louisi
Modified quantitative structure retention relationships (QSRRs) are proposed and applied to describe two retention data sets: A set of 94 metabolites studied by a hydrophilic interaction chromatography system under organic content gradient conditions and a set of tryptophan and its major metabolites analyzed by a reversed-phase chromatographic system under isocratic as well as pH and/or simultaneous pH and organic content gradient conditions. According to the proposed modification, an additional descriptor is added to a conventional QSRR expression, which is the analyte retention time, tR(R), measured under the same elution conditions, but in a second chromatographic column considered as a reference one...
February 9, 2017: Metabolites
https://www.readbyqxmd.com/read/28195418/upconversion-nanoparticles-synthesized-by-ultra-short-pulsed-laser-ablation-in-liquid-effect-of-stabilizing-environment
#3
Laura Gemini, Tim Schmitz, Rainer Kling, Stephan Barcikowski, Bilal Gökce
The distinctive feature of upconverting compounds to absorb and emit light in the near-infrared region has made upconverting nanoparticles of great interest in various application fields. Nevertheless, these colloids show highly hydrophobic behavior and therefore the use of a proper stabilizing agent is necessary in most cases. Although few chemical techniques for colloid stabilization are available, it is still difficult to achieve a fully reproducible synthesis method for stable upconverting nanoparticle colloids...
February 14, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28180226/facile-fabrication-of-sudan-red-particle-microcapsules-by-a-polymerizable-gemini-surfactant-and-molecular-assembly-mechanisms
#4
Yaqian Wu, Haike Yan, Xuefeng Shi, Jinben Wang
An efficient method was developed to encapsulate water insoluble organic particles of Sudan red III (SR) in aqueous suspensions by using a polymerizable cationic gemini surfactant, 1,3-bis(N,N-dimethyl-N-cetylammonium)-2-(propylacrylate dibromide) (AGC16). The AGC16 coated SR microcapsules (AGC16@SR) were prepared by absorption of AGC16 on the surface of SR, followed by in situ homopolymerization (PAGC16). Several measurements, including transmission and scanning electron microscopy, isothermal titration calorimetry, zeta potential, electron paramagnetic resonance and small angle X-ray scattering, were performed to determine the adsorption amount of AGC16, and the layer structures and the molecular assembly mechanism in the AGC16@SR and PAGC16@SR systems, respectively...
February 9, 2017: Soft Matter
https://www.readbyqxmd.com/read/28174921/dop026-sustained-remission-with-vedolizumab-in-patients-with-moderately-to-severely-active-ulcerative-colitis-a-gemini-1-post-hoc-analysis-of-week-14-remitters
#5
A Stallmach, B Bokemeyer, J Axler, R Curtis, R Ehehalt, B Feagan, P Geransar, A James, A Kaviya, J M Khalid, D Wolf, S Schreiber
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172706/dop021-long-term-effectiveness-and-safety-of-vedolizumab-in-patients-with-crohn-s-disease-5-year-cumulative-exposure-of-gemini-2-completers-rolling-into-the-gemini-open-label-extension-study
#6
S Vermeire, E V Loftus, J-F Colombel, B Feagan, W Sandborn, B Sands, S Danese, G D'Haens, A Kaser, R Panaccione, D Rubin, I Shafran, S O'Byrne, P Geransar, A Previtali, J M Khalid, A Kaviya
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172630/dop019-effect-of-vedolizumab-treatment-on-extraintestinal-manifestations-in-patients-with-crohn-s-disease-a%C3%A2-gemini-2-post-hoc-analysis
#7
B G Feagan, W J Sandborn, J-F Colombel, S O'Byrne, J M Khalid, N Brayshaw, P Geransar, D T Rubin
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172545/p209-long-term-effectiveness-and-safety-of-vedolizumab-in-patients-with-ulcerative-colitis-5-year-cumulative-exposure-of-gemini-1-completers-rolling-into-the-gemini-open-label-extension-study
#8
E V Loftus, J-F Colombel, B Feagan, S Vermeire, W Sandborn, B Sands, S Danese, G D'Haens, A Kaser, R Panaccione, D Rubin, I Shafran, S O'Byrne, P Geransar, A James, A Kaviya, J M Khalid
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28168729/novel-uhplc-ms-ms-method-for-the-determination-of-rotigotine-in-the-plasma-of-patients-with-parkinson-s-disease
#9
Susan Mohamed, Roberto Riva, Manuela Contin
A novel ultra high pressure liquid chromatography-tandem mass spectrometry method was developed and validated for the determination of the dopamine receptor agonist rotigotine in human plasma. Following liquid-liquid extraction with tert-butyl methyl ether from 500 μL plasma, the chromatographic analysis was performed on a Gemini NX3 column using 5 mM pH 5.0 ammonium acetate/5 mM ammonium acetate in methanol as binary gradient mobile phase, at a flow rate of 0.3 mL/min. The MS/MS ion transitions were 316...
February 6, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28139691/the-hypothalamic-npvf-circuit-modulates-ventral-raphe-activity-during-nociception
#10
Romain Madelaine, Matthew Lovett-Barron, Caroline Halluin, Aaron S Andalman, Jin Liang, Gemini M Skariah, Louis C Leung, Vanessa M Burns, Philippe Mourrain
RFamide neuropeptide VF (NPVF) is expressed by neurons in the hypothalamus and has been implicated in nociception, but the circuit mechanisms remain unexplored. Here, we studied the structural and functional connections from NPVF neurons to downstream targets in the context of nociception, using novel transgenic lines, optogenetics, and calcium imaging in behaving larval zebrafish. We found a specific projection from NPVF neurons to serotonergic neurons in the ventral raphe nucleus (vRN). We showed NPVF neurons and vRN are suppressed and excited by noxious stimuli, respectively...
January 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28130141/starch-based-xerogels-effect-of-acetylation-on-physicochemical-and-rheological-properties
#11
Chinwe U Kemas, Ndidi C Ngwuluka, Nelson A Ochekpe, Elijah I Nep
This study was aimed at evaluating the physicochemical and rheological properties of starch-based xerogels. The starch from the shoots of Borassus aethiopium was physically modified by xerogelization, and chemically by acetylation, and combination of acetylation and xerogelization. The solubility, swelling and syneresis of the starches were determined by gravimetric techniques. Evaluation of the native starch and derivatives was done using microscopy, Fourier transform infra-red (FTIR), x-ray diffractometry (XRD), and (1)H NMR spectroscopy...
January 24, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28127535/mandibular-arch-orthodontic-treatment-stability-using-passive-self-ligating-and-conventional-systems-in-adults-a-randomized-controlled-trial
#12
Norma Ab Rahman, Mang Chek Wey, Siti Adibah Othman
OBJECTIVE: This randomized controlled trial aimed to compare the stability of mandibular arch orthodontic treatment outcomes between passive self-ligating and conventional systems during 6 months of retention. METHODS: Fortyseven orthodontic patients with mild to moderate crowding malocclusions not requiring extraction were recruited based on inclusion criteria. Patients (mean age 21.58 ± 2.94 years) were randomized into two groups to receive either passive self-ligating (Damon® 3MX, n = 23) or conventional system (Gemini MBT, n = 24) orthodontic treatment...
January 2017: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/28120957/coarse-grained-molecular-dynamics-study-on-the-self-assembly-of-gemini-surfactants-the-effect-of-spacer-length
#13
Pan Wang, Shuai Pei, Muhan Wang, Youguo Yan, Xiaoli Sun, Jun Zhang
Gemini surfactants cause a lot of concerns owing to their unusual aggregation morphologies and superior physicochemical properties over the conventional surfactants. Research shows that the unique structure of Gemini surfactants, especially the spacer group, has a great impact on the self-assembly behaviors. To understand the determinants of this behavior on the molecular level, we carried out coarse-grained molecular dynamics (CGMD) simulations on aqueous solutions of alkanediyl-a,w-bis (dimethylcetylammonium bromide)-based surfactants with different spacer group lengths...
January 25, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28111493/molecular-connectivity-indices-for-modeling-the-critical-micelle-concentration-of-cationic-chloride-gemini-surfactants
#14
Anna Mozrzymas
The molecular connectivity indices were used to derive the simple model relating the critical micelle concentration of cationic (chloride) gemini surfactants to their structure. One index was selected as the best to describe the effect of the structure of investigated compounds on critical micelle concentration consistent with the experimental results. This index encodes the information about molecular size, the branches, and also the information about heteroatoms. The selected model can be helpful in designing novel chloride gemini surfactants...
2017: Colloid and Polymer Science
https://www.readbyqxmd.com/read/28098305/phase-behaviour-and-temperature-responsive-properties-of-a-gemini-surfactant-brij-30-water-system
#15
Chuanhong Han, Yan Guo, Xiaoxiao Chen, Meihuan Yao, Yingtian Zhang, Qirui Zhang, Xilian Wei
The phase behaviour of a ternary system composed of cationic gemini surfactant 2-hydroxypropyl-1,3-bis(myristyldimethylammonium chloride) (14-3(OH)-14(2Cl)), nonionic surfactant polyoxyethylene laurel ether (C12H25(OCH2CH2)10OH, Brij-30) and H2O was studied and its phase diagram was determined. In several different phase regions identified in the phase diagram, the viscoelastic worm-like micellar solution region was investigated. The focus of the investigation was the increase in the viscosity of the micellar solution with the temperature and the Brij-30 content, as suggested by a partial region of the triangular phase diagram...
January 18, 2017: Soft Matter
https://www.readbyqxmd.com/read/28093968/quantification-of-etodolac-in-human-plasma-for-pharmacokinetics-and-bioequivalence-studies-in-27-korean-subjects
#16
Il-Dong Song, Je-Seop Kang, Hyun-Jin Kim, Se-Mi Kim, Dong-Xu Zhao, Shin-Hee Kim, Min-Young Chun, Kyuhyun Lee
We developed a simple and validated liquid chromatography tandem mass spectrometry(LC-MS/MS) for quantification of etodolac using pioglitazone as an internal standard (IS) to assess pharmacokinetics and to appraise bioequivalence of two formulations of etodolac (reference and tested) in 27 healthy Korean subjects. Isocratic mobile phase consisted of 10 mM ammonium formate and acetonitrile were used to separate the analytes on a Gemini C18 column. Also, analytes were analyzed by MS/MS in multiple reaction monitoring (MRM) mode using the transitions of (M+H)+ ions, m/z 288...
16, 2017: Drug Metabolism Letters
https://www.readbyqxmd.com/read/28079203/complexation-of-short-ds-rna-dna-oligonucleotides-with-gemini-micelles-a-time-resolved-saxs-and-computational-study
#17
Sara Falsini, Emanuela Di Cola, Martin In, Maria Giordani, Stefano Borocci, Sandra Ristori
Gene therapy is based on nucleic acid delivery to pathogenic cells in order to modulate their gene expression. The most used non viral vectors are lipid-based nanoaggregates, which are safer than viral carriers and have been shown to assemble easily with both DNA and RNA. However, the transfection efficiency of non viral carriers still needs to be improved before intensive practise in clinical trials can be implemented. For this purpose, the in depth characterization of the complexes formed by nucleic acids and their transporters is of great relevance...
January 12, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28070861/efficacy-and-safety-of-vedolizumab-in-ulcerative-colitis-and-crohn-s-disease-patients-stratified-by-age
#18
Vijay Yajnik, Nabeel Khan, Marla Dubinsky, Jeffrey Axler, Alexandra James, Brihad Abhyankar, Karen Lasch
INTRODUCTION: The efficacy and safety of vedolizumab, a gut-selective α4β7 integrin antibody, were demonstrated in the GEMINI 1 and GEMINI 2 clinical trials of adults aged 18-80 years. We investigated the efficacy and safety of vedolizumab in patients stratified by age from the GEMINI trials. METHODS: Safety and efficacy, including clinical response, clinical remission, and corticosteroid-free remission, at week 6 and/or 52 were determined post hoc in patients aged <35, 35 to <55, and ≥55 years...
January 9, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28065896/ge-mini-a-mobile-app-for-large-scale-gene-expression-visualization
#19
Zefang Tang, Chenwei Li, Karena Zhang, Mingyu Yang, Xueda Hu
: The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) projects produced large-scale RNA sequencing data, which provides an opportunity for performing integrated expression analysis for all genes across tens of thousands of tumor and normal tissue specimens. Rapid access to and easy visualization of such valuable data could facilitate research in a wide biological area. Here, we present the GE-mini APP for smart phones, a mobile visualization tool for integrated gene expression data based on both TCGA and GTEx...
January 8, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28050507/shear-bond-strength-of-ceramic-brackets-with-different-base-designs-comparative-in-vitro-study
#20
Mohd Younus Ansari, Deepak K Agarwal, Ankur Gupta, Preeti Bhattacharya, Juhi Ansar, Ravi Bhandari
INTRODUCTION: Knowledge about the Shear Bond Strength (SBS) of ceramic brackets with different base design is essential as it affects bond strength to enamel. AIM: The aim of the present study was to evaluate and compare the effect of base designs of different ceramic brackets on SBS, and to determine the fracture site after debonding. MATERIALS AND METHODS: Four groups of ceramic brackets and one group of metal brackets with different base designs were used...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
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