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https://www.readbyqxmd.com/read/28537109/facial-and-prosodic-emotion-recognition-in-social-anxiety-disorder
#1
Huai-Hsuan Tseng, Yu-Lien Huang, Jian-Ting Chen, Kuei-Yu Liang, Chao-Cheng Lin, Sue-Huei Chen
INTRODUCTION: Patients with social anxiety disorder (SAD) have a cognitive preference to negatively evaluate emotional information. In particular, the preferential biases in prosodic emotion recognition in SAD have been much less explored. The present study aims to investigate whether SAD patients retain negative evaluation biases across visual and auditory modalities when given sufficient response time to recognise emotions. METHODS: Thirty-one SAD patients and 31 age- and gender-matched healthy participants completed a culturally suitable non-verbal emotion recognition task and received clinical assessments for social anxiety and depressive symptoms...
May 24, 2017: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/28532686/mismatch-negativity-mmn-to-spatial-deviants-and-behavioral-spatial-discrimination-ability-in-the-etiology-of-auditory-verbal-hallucinations-and-thought-disorder-in-schizophrenia
#2
Megan A Perrin, Joshua T Kantrowitz, Gail Silipo, Elisa Dias, Omar Jabado, Daniel C Javitt
Persistent auditory verbal hallucinations (AVH) in schizophrenia are increasingly tied to dysfunction at the level of auditory cortex. AVH may reflect in part misattribution of internally generated thoughts to external spatial locations. Here, we investigated the association between persistent AVH and spatial localization abilities assessed both behaviorally and by mismatch negativity (MMN) to location deviants. METHODS: Spatial- and tonal- discrimination abilities were assessed in patients (n=20) and controls (n=20) using free-field tones...
May 19, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28529495/determining-the-association-between-language-and-cognitive-tests-in-poststroke-aphasia
#3
Kylie J Wall, Toby B Cumming, David A Copland
BACKGROUND: Individuals with aphasia are often excluded from studies exploring poststroke cognition because so many of the standard cognitive assessments rely on language ability. Our primary objective was to examine the association between performance on cognitive tests and performance on comprehension and naming tests in poststroke aphasia. Second, we aimed to determine the association between language performance and a real-life measure of cognition (Kettle Test). Third, we explored the feasibility of administering cognitive tests in aphasia...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28526621/electrophysiological-signatures-of-phonological-and-semantic-maintenance-in-sentence-repetition
#4
Jed A Meltzer, Aneta Kielar, Lilia Panamsky, Kira A Links, Tiffany Deschamps, Rosie C Leigh
Verbal short-term memory comprises resources for phonological rehearsal, which have been characterized anatomically, and for maintenance of semantic information, which are less understood. Sentence repetition tasks tap both processes interactively. To distinguish brain activity involved in phonological vs. semantic maintenance, we recorded magnetoencephalography during a sentence repetition task, incorporating three manipulations emphasizing one mechanism over the other. Participants heard sentences or word lists and attempted to repeat them verbatim after a 5-second delay...
May 16, 2017: NeuroImage
https://www.readbyqxmd.com/read/28522971/altered-functional-connectivity-of-the-basal-nucleus-of-meynert-in-mild-cognitive-impairment-a-resting-state-fmri-study
#5
Hui Li, Xiuqin Jia, Zhigang Qi, Xiang Fan, Tian Ma, Hong Ni, Chiang-Shan R Li, Kuncheng Li
Background: Cholinergic dysfunction plays an important role in mild cognitive impairment (MCI). The basal nucleus of Meynert (BNM) provides the main source of cortical cholinergic innervation. Previous studies have characterized structural changes of the cholinergic basal forebrain in individuals at risk of developing Alzheimer's disease (AD). However, whether and how functional connectivity of the BNM (BNM-FC) is altered in MCI remains unknown. Objective: The aim of this study was to identify alterations in BNM-FC in individuals with MCI as compared to healthy controls (HCs), and to examine the relationship between these alterations with neuropsychological measures in individuals with MCI...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28516807/neurofeedback-based-enhancement-of-single-trial-auditory-evoked-potentials-feasibility-in-healthy-subjects
#6
Kathryn Rieger, Marie-Helene Rarra, Nicolas Moor, Laura Diaz Hernandez, Anja Baenninger, Nadja Razavi, Thomas Dierks, Daniela Hubl, Thomas Koenig
Previous studies showed a global reduction of the event-related potential component N100 in patients with schizophrenia, a phenomenon that is even more pronounced during auditory verbal hallucinations. This reduction assumingly results from dysfunctional activation of the primary auditory cortex by inner speech, which reduces its responsiveness to external stimuli. With this study, we tested the feasibility of enhancing the responsiveness of the primary auditory cortex to external stimuli with an upregulation of the event-related potential component N100 in healthy control subjects...
May 1, 2017: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/28513073/early-neurocognitive-improvements-following-parathyroidectomy-for-primary-hyperparathyroidism
#7
Shivani Shah-Becker, Jonathan Derr, Benjamin S Oberman, Aaron Baker, Brian Saunders, Michele M Carr, David Goldenberg
OBJECTIVES: To establish a time frame for postoperative improvements in neurocognitive function in patients who undergo parathyroidectomy for primary hyperparathyroidism by utilizing repeat neuropsychological assessment at multiple time points before and after surgery. STUDY DESIGN: Prospective cohort study. METHODS: A prospective study was conducted at a tertiary academic medical center between August 2014 and December 2015, including 50 patients with primary hyperparathyroidism who underwent parathyroidectomy...
May 16, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28511918/molecular-imaging-of-serotonin-degeneration-in-mild-cognitive-impairment
#8
Gwenn S Smith, Frederick S Barrett, Jin Hui Joo, Najlla Nassery, Alena Savonenko, Devin J Sodums, Christopher M Marano, Cynthia A Munro, Jason Brandt, Michael A Kraut, Yun Zhou, Dean F Wong, Clifford I Workman
Neuropathological and neuroimaging studies have consistently demonstrated degeneration of monoamine systems, especially the serotonin system, in normal aging and Alzheimer's disease. The evidence for degeneration of the serotonin system in mild cognitive impairment is limited. Thus, the goal of the present study was to measure the serotonin transporter in vivo in mild cognitive impairment and healthy controls. The serotonin transporter is a selective marker of serotonin terminals and of the integrity of serotonin projections to cortical, subcortical and limbic regions, as well as the cell bodies of origin (raphe nuclei)...
May 13, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/28502691/long-term-seizure-quality-of-life-depression-and-verbal-memory-outcomes-in-a-controlled-mesial-temporal-lobe-epilepsy-surgical-series-using-portuguese-validated-instruments
#9
Luis Dias, Geisa Angelis, Wagner Teixeira, Luiz Casulari
OBJECTIVE: We aimed to evaluate long-term surgical outcomes in patients treated for mesial temporal lobe epilepsy (MTLE) compared to a similar group of patients that underwent a preoperative evaluation. METHODS: Patient interviews were conducted by an independent neuropsychologist and included a socio-demographic questionnaire and validated versions of the Beck Depression Inventory-II (BDI-II), Adverse Events Profile (AEP), Quality of Life in Epilepsy-31 (QOLIE-31), and Rey Auditory Verbal Learning Test (RAVLT)...
May 11, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28497892/echoes-of-others-a-path-analytic-examination-of-an-interpersonal-cognitive-model-of-voice-related-distress
#10
Esther R Cole, Clara Strauss, Chris Fife-Schaw, Simon McCarthy-Jones
OBJECTIVES: Cognitive models propose that levels of distress associated with auditory verbal hallucinations ('voices') are influenced by the hearers' beliefs about their voices (perceived malevolence and omnipotence), their negative beliefs about themselves and others and their attachment style. This study aims to test a comprehensive model of the relationship between these variables in order to identify distal and proximal interpersonal and cognitive factors contributing to voice-related distress...
May 12, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28493090/-impaired-recognition-of-environmental-sounds-in-patients-with-dementia-i%C3%A2-can-hear-but-i%C3%A2-do-not-understand
#11
Birgit Dietz, Sarah Kohl, Johannes Mayer, Christoph Metzger, Hans Förstl, Janine Diehl-Schmid
BACKGROUND: Impairment of central auditory processing is a well-known symptom of neurodegenerative dementia; however, whilst numerous studies have examined verbal processing impairment, to date few have attempted to describe impairments of non-verbal, environmental sound recognition in patients with dementia. As these impairments may have direct implications on patient support and care, such studies are urgently necessary. AIM OF THE STUDY: The aim of the study was to determine whether the recognition of meaningful environmental sounds is impaired in patients with mild or early stage neurodegenerative dementia...
May 10, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28492912/auditory-verbal-working-memory-as-a-predictor-of-speech-perception-in-modulated-maskers-in-listeners-with-normal-hearing
#12
Rebecca E Millman, Sven L Mattys
Purpose: Background noise can interfere with our ability to understand speech. Working memory capacity (WMC) has been shown to contribute to the perception of speech in modulated noise maskers. WMC has been assessed with a variety of auditory and visual tests, often pertaining to different components of working memory. This study assessed the relationship between speech perception in modulated maskers and components of auditory verbal working memory (AVWM) over a range of signal-to-noise ratios...
May 24, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28465538/how-doctors-diagnose-diseases-and-prescribe-treatments-an-fmri-study-of-diagnostic-salience
#13
Marcio Melo, Gustavo D F Gusso, Marcelo Levites, Edson Amaro, Eduardo Massad, Paulo A Lotufo, Peter Zeidman, Cathy J Price, Karl J Friston
Understanding the brain mechanisms involved in diagnostic reasoning may contribute to the development of methods that reduce errors in medical practice. In this study we identified similar brain systems for diagnosing diseases, prescribing treatments, and naming animals and objects using written information as stimuli. Employing time resolved modeling of blood oxygen level dependent (BOLD) responses enabled time resolved (400 milliseconds epochs) analyses. With this approach it was possible to study neural processes during successive stages of decision making...
May 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28463217/-neuropsychological-performance-in-patients-with-myasthenia-gravis
#14
María Bárbara Eizaguirre, Florencia Aguirre, Cecilia Yastremiz, Sandra Vanotti, Andrés Villa
Myasthenia gravis is a chronic autoimmune disease that affects the neuromuscular transmission. Controversial findings had been reported about cognitive impairment in this disease. The aim of this study was to investigate the cognitive pattern of patients with myasthenia gravis. There were enrolled 24 patients with myasthenia gravis, anti-acetylcholine receptor antibodies (ACRA) positive, and 24 healthy controls. PATIENTS: age 43.9 ± 14.8, years of education 10.9 ± 3.3. CONTROLS: age 44...
2017: Medicina
https://www.readbyqxmd.com/read/28453532/feasibility-of-computerized-working-memory-training-in-individuals-with-huntington-disease
#15
Mahsa Sadeghi, Emily Barlow-Krelina, Clare Gibbons, Komal T Shaikh, Wai Lun Alan Fung, Wendy S Meschino, Christine Till
OBJECTIVES: Huntington disease (HD) is associated with a variety of cognitive deficits, with prominent difficulties in working memory (WM). WM deficits are notably compromised in early-onset and prodromal HD patients. This study aimed to determine the feasibility of a computerized WM training program (Cogmed QM), novel to the HD population. METHODS: Nine patients, aged 26-62, with early stage HD underwent a 25-session (5 days/week for 5 weeks) WM training program (Cogmed QM)...
2017: PloS One
https://www.readbyqxmd.com/read/28450976/exploring-modality-compatibility-in-the-response-effect-compatibility-paradigm
#16
Noémi Földes, Andrea M Philipp, Arnaud Badets, Iring Koch
According to ideomotor theory, action planning is based on anticipatory perceptual representations of action-effects. This aspect of action control has been investigated in studies using the response-effect compatibility (REC) paradigm, in which responses have been shown to be facilitated if ensuing perceptual effects share codes with the response based on dimensional overlap (i.e., REC). Additionally, according to the notion of ideomotor compatibility, certain response-effect (R-E) mappings will be stronger than others because some response features resemble the anticipated sensory response effects more strongly than others (e...
2017: Advances in Cognitive Psychology
https://www.readbyqxmd.com/read/28446207/memory-is-preserved-in-older-adults-taking-at1-receptor-blockers
#17
Jean K Ho, Daniel A Nation
BACKGROUND: Prior work suggests that some but not all antihypertensive treatments may benefit cognition and risk for Alzheimer's disease, independent of stroke. Angiotensin II receptor blockers (ARBs) have been highlighted as one antihypertensive drug class that may confer greatest benefit. METHODS: The participants comprised 1626 nondemented adults, aged 55-91 years, recruited from Alzheimer's Disease Neuroimaging Initiative sites. Three groups were compared: ARB users (HTN-ARBs), other antihypertensive drug users (HTN-Other), and normotensives...
April 26, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28443036/auditory-motor-rhythms-and-speech-processing-in-french-and-german-listeners
#18
Simone Falk, Chloé Volpi-Moncorger, Simone Dalla Bella
Moving to a speech rhythm can enhance verbal processing in the listener by increasing temporal expectancies (Falk and Dalla Bella, 2016). Here we tested whether this hypothesis holds for prosodically diverse languages such as German (a lexical stress-language) and French (a non-stress language). Moreover, we examined the relation between motor performance and the benefits for verbal processing as a function of language. Sixty-four participants, 32 German and 32 French native speakers detected subtle word changes in accented positions in metrically structured sentences to which they previously tapped with their index finger...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28442422/effects-of-low-frequency-rtms-treatment-on-brain-networks-for-inner-speech-in-patients-with-schizophrenia-and-auditory-verbal-hallucinations
#19
Leonie Bais, Edith Liemburg, Ans Vercammen, Richard Bruggeman, Rikus Knegtering, André Aleman
INTRODUCTION: Efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) targeting the temporo-parietal junction (TPJ) for the treatment of auditory verbal hallucinations (AVH) remains under debate. We assessed the influence of a 1Hz rTMS treatment on neural networks involved in a cognitive mechanism proposed to subserve AVH. METHODS: Patients with schizophrenia (N=24) experiencing medication-resistant AVH completed a 10-day 1Hz rTMS treatment. Participants were randomized to active stimulation of the left or bilateral TPJ, or sham stimulation...
April 22, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28433073/neurocognitive-function-in-clinically-stable-individuals-with-long-term-bipolar-i-disorder-comparisons-with-schizophrenia-patients-and-controls
#20
Pei-Yun Lin, Peng-Wei Wang, Cheng-Sheng Chen, Cheng-Fang Yen
This study compared the levels of the five domains of neurocognitive function-executive function, attention, memory, verbal comprehension, and perceptual organization-among clinically stable individuals with long-term bipolar I disorder, individuals with long-term schizophrenia, and a group of controls. We recruited a total of 93 clinically stable individuals with bipolar I disorder, 94 individuals with schizophrenia, and 106 controls in this study. Their neurocognitive function was measured using a series of neurocognitive function tests: the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III), Line Cancellation Test, Visual Form Discrimination, Controlled Oral Word Association Test, Wisconsin Card Sorting Test, Continuous Performance Task, and Wechsler Memory Scale-Third Edition...
May 2017: Kaohsiung Journal of Medical Sciences
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