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Newborn hearing

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https://www.readbyqxmd.com/read/28441153/discharge-criteria-for-the-late-preterm-infant-a-review-of-the-literature
#1
Jenny M Quinn, Marteen Sparks, Sheila M Gephart
BACKGROUND: Standardized late preterm infant (LPI) discharge criteria ensure best practice and help guide the neonatal provider to determine the appropriate level of care following birth. However, the location can vary from the well newborn setting to the neonatal intensive care unit (NICU). PURPOSE: The purpose of this review is to examine differences in LPI discharge criteria between the well newborn setting and the NICU by answering the clinical questions, "What are the recommended discharge criteria for the LPI and do they differ if admitted to the well newborn setting versus the NICU?" SEARCH STRATEGY: Databases searched include CINAHL, TRIP, PubMed, and the Cochrane Library...
April 24, 2017: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28424585/efr3a-insufficiency-attenuates-the-degeneration-of-spiral-ganglion-neurons-after-hair-cell-loss
#2
Haixia Hu, Bin Ye, Le Zhang, Quan Wang, Zhiwei Liu, Suying Ji, Qiuju Liu, Jingrong Lv, Yan Ma, Ying Xu, Hao Wu, Fude Huang, Mingliang Xiang
Sensorineural hearing loss (SNHL) is caused by an irreversible impairment of cochlear hair cells and subsequent progressive degeneration of spiral ganglion neurons (SGNs). Eighty-five requiring 3 (Efr3) is a plasma membrane protein conserved from yeast to human, and knockout of Efr3a was reported to facilitate the survival of hippocampal newborn neurons in adult mice. Previously, we found Efr3a expression in the auditory neural pathway is upregulated soon after the destruction of hair cells. Here we conducted a time-course analysis of drug-caused damage to hearing ability, hair cells and SGNs in Efr3a knocking down mice (Efr3a(-/+), Efr3a KD) and their wild type littermates...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/28420769/newborn-hearing-screening-making-a-difference
#3
Marcia Fort
Newborn hearing screening has become the standard of care in the United States, with over 98% of infants born screened for hearing loss. Appropriate and timely follow-up is critical when an infant does not pass the screening. While there remains room for improvement, newborn hearing screening is making a difference.
March 2017: North Carolina Medical Journal
https://www.readbyqxmd.com/read/28404573/cytomegalovirus-virions-shed-in-urine-have-a-reversible-block-to-epithelial-cell-entry-and-are-highly-resistant-to-antibody-neutralization
#4
Xiaohong Cui, Stuart P Adler, Mark R Schleiss, Ravit Arav-Boger, Gail J Demmler Harrison, Michael A McVoy
Cytomegalovirus (CMV) causes sensorineural hearing loss and developmental disabilities in newborns when infections are aquired in utero Pregnant women may acquire CMV from oral exposure to CMV in urine or saliva from young children. Neutralizing antibodies in maternal saliva have potential to prevent maternal infection and in turn fetal infection. As CMV uses different viral glycoprotein complexes to enter different cell types, the first cells to be infected in the oral cavity could determine the type of antibodies needed to disrupt oral transmission...
April 12, 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28399063/language-outcomes-in-deaf-or-hard-of-hearing-teenagers-who-are-spoken-language-users-effects-of-universal-newborn-hearing-screening-and-early-confirmation
#5
Hannah Pimperton, Jana Kreppner, Merle Mahon, Jim Stevenson, Emmanouela Terlektsi, Sarah Worsfold, Ho Ming Yuen, Colin R Kennedy
OBJECTIVES: This study aimed to examine whether (a) exposure to universal newborn hearing screening (UNHS) and b) early confirmation of hearing loss were associated with benefits to expressive and receptive language outcomes in the teenage years for a cohort of spoken language users. It also aimed to determine whether either of these two variables was associated with benefits to relative language gain from middle childhood to adolescence within this cohort. DESIGN: The participants were drawn from a prospective cohort study of a population sample of children with bilateral permanent childhood hearing loss, who varied in their exposure to UNHS and who had previously had their language skills assessed at 6-10 years...
April 10, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28395068/factors-related-to-not-following-up-with-recommended-testing-in-the-diagnosis-of-newborn-hearing-loss
#6
Wendy Zeitlin, Charles Auerbach, Susan E Mason, Lynn G Spivak, Bena Reiter
Children's hearing is a public health concern, and universal newborn hearing screenings are the first step in detecting and treating congenital hearing loss. Despite the high rate of participation in such programs, loss to follow-up (LTF) with additional recommended diagnosis and treatment has been a persistent problem. The current research seeks to expand the knowledge base at the point of diagnosis, where there is a large drop-off in parents following through with recommended care. This research was organized around the following question: What biopsychosocial factors are associated with LTF between screenings and diagnostic evaluations? A prospective quantitative longitudinal study tracked 203 families whose newborns were referred for additional testing at discharge from the hospital after birth...
February 1, 2017: Health & Social Work
https://www.readbyqxmd.com/read/28390612/the-results-of-newborn-hearing-screening-by-means-of-transient-otoacoustic-emissions-has-anything-changed-over-10-years
#7
Katarzyna Wroblewska-Seniuk, Grazyna Greczka, Piotr Dabrowski, Witold Szyfter, Jan Mazela
OBJECTIVES: Universal newborn hearing screening (UNHS) has become the standard of care in many countries. The aim of this study was to evaluate the results of UNHS after ten years of the program in Poland and to compare them with the results of 2003. METHODS: In the study, we analyze the results of UNHS in the University Hospital in Poznan, Poland. Between 01.01.2013 and 31.12.2013, 6827 children were examined by means of otoacoustic emissions. RESULTS: Risk factors (RF) were identified in 772 (11...
May 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28390610/myo15a-splicing-mutations-in-hearing-loss-a-review-literature-and-report-of-a-novel-mutation
#8
Mahsa Motavaf, Mahdieh Soveizi, Majid Maleki, Nejat Mahdieh
Sensorineural hearing loss (SNHL) is the most prevalent genetic sensory defect in humans, affecting about 1 in 1000 newborns around the world. Non-syndromic SNHL accounts for nearly 70% of hereditary hearing loss and 80% of SNHL cases show an autosomal recessive mode of inheritance (ARNSHL). In the present study, we applied targeted-exome sequencing to a family with a single proband affected by congenital sensorineural hearing loss. 127 known genes were sequenced to find the causative mutation. One novel homozygous donor splice site mutation, c...
May 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28385167/hearing-screening-in-newborns-in-the-central-denmark-region
#9
Linda Busk Linnebjerg, Anita Ekman Hansen, Troels Reinholdt Møller
INTRODUCTION: In 2005, a nationwide programme on hearing screening in newborns was launched in Denmark. The purpose of the programme was to ensure early detection of hearing loss in newborns and to institute subsequent treatment. The aim of this study was to assess whether the Central Denmark Region observes the guidelines of the Danish Health and Medicines Authority (DHMA) for neonatal hearing. In addition, we wanted to identify factors that may influence screening density positively or negatively...
April 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28384133/vital-signs-update-on-zika-virus-associated-birth-defects-and-evaluation-of-all-u-s-infants-with-congenital-zika-virus-exposure-u-s-zika-pregnancy-registry-2016
#10
Megan R Reynolds, Abbey M Jones, Emily E Petersen, Ellen H Lee, Marion E Rice, Andrea Bingham, Sascha R Ellington, Nicole Evert, Sarah Reagan-Steiner, Titilope Oduyebo, Catherine M Brown, Stacey Martin, Nina Ahmad, Julu Bhatnagar, Jennifer Macdonald, Carolyn Gould, Anne D Fine, Kara D Polen, Heather Lake-Burger, Christina L Hillard, Noemi Hall, Mahsa M Yazdy, Karnesha Slaughter, Jamie N Sommer, Alys Adamski, Meghan Raycraft, Shannon Fleck-Derderian, Jyoti Gupta, Kimberly Newsome, Madelyn Baez-Santiago, Sally Slavinski, Jennifer L White, Cynthia A Moore, Carrie K Shapiro-Mendoza, Lyle Petersen, Coleen Boyle, Denise J Jamieson, Dana Meaney-Delman, Margaret A Honein
BACKGROUND: In collaboration with state, tribal, local, and territorial health departments, CDC established the U.S. Zika Pregnancy Registry (USZPR) in early 2016 to monitor pregnant women with laboratory evidence of possible recent Zika virus infection and their infants. METHODS: This report includes an analysis of completed pregnancies (which include live births and pregnancy losses, regardless of gestational age) in the 50 U.S. states and the District of Columbia (DC) with laboratory evidence of possible recent Zika virus infection reported to the USZPR from January 15 to December 27, 2016...
April 7, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28353523/early-hearing-detection-and-intervention-pediatric-audiology-links-to-services-ehdi-pals-building-a-national-facility-database
#11
Winnie Chung, Kathryn L Beauchaine, Jeff Hoffman, Kirsten R Coverstone, Anne Oyler, Craig Mason
OBJECTIVES: To create a searchable web-based national audiology facility directory using a standardized survey, so parents and providers could identify which facilities had capacity to provide appropriate services based on child's age. DESIGN: An Early Hearing Detection and Intervention-Pediatric Audiology Links to Services expert panel was convened to create a survey to collect audiology facility information. Professional practice documents were reviewed, a survey was designed to collect pertinent test protocols of each audiology facility, and a standard of care template was created to cross-check survey answers...
March 28, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28330595/electrophysiological-exploration-of-hearing
#12
D Bakhos, M Marx, A Villeneuve, E Lescanne, S Kim, A Robier
Electrophysiologic hearing tests have been developed since the 1960s to determine hearing thresholds objectively. They are now implemented in newborn hearing screening. While they determine thresholds, interpretation requires subjective pure-tone and speech audiometry to determine the type of hearing loss. Each examination tests a different anatomic region, enabling the auditory system to be explored from the organ of Corti to the auditory cortex. Thus, the various objective audiometric examinations are complementary...
March 16, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28322432/bilateral-congenital-deafness-what-investigations-should-be-performed
#13
Nicolas Gürtler, Claudine Gysin, Nevenka Schmid, Claudia Pieren, Mattheus Vischer, Stefan Schumacher, Peter Oppermann, Daniel Leuba, Dorothée Veraguth
BACKGROUND: The introduction of newborn hearing screening has led to earlier identification of children with congenital sensorineural hearing loss (SNHL). Aetiological clarification offers several benefits. There is currently a lack of agreement on which examinations should be recommended. OBJECTIVE: Descriptive review of the literature reporting investigations performed to establish the aetiology of congenital SNHL and comparison of the management policy in Swiss referral centres...
March 21, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28298291/plasmablast-response-to-primary-rhesus-cytomegalovirus-infection-in-a-monkey-model-of-congenital-cmv-transmission
#14
Qihua Fan, Cody S Nelson, Kristy M Bialas, Flavia Chiuppesi, Joshua Amos, Thaddeus C Gurley, Dawn Jones Marshall, Joshua Eudailey, Holly Heimsath, Jonathon Himes, Ashlesha Deshpande, Mark R Walter, Felix Wussow, Don J Diamond, Peter A Barry, M Anthony Moody, Amitinder Kaur, Sallie R Permar
Human cytomegalovirus (HCMV) is the most common congenital infection worldwide, and the leading infectious cause of neurologic deficits and hearing loss in newborns. Development of a maternal HCMV vaccine to prevent vertical virus transmission is a high priority, yet protective maternal immune responses following acute infection are poorly understood. To characterize the maternal humoral immune response to primary CMV infection, we investigated the plasmablast and early antibody repertoire using a nonhuman primate model with two acutely rhesus CMV (RhCMV) infected animals - a CD4+ T cell-depleted dam that experienced fetal loss shortly after vertical RhCMV transmission and an immunocompetent dam that did not transmit RhCMV to her infant...
March 15, 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28291720/congenital-cytomegalovirus-infection-in-pregnancy-and-the-neonate-consensus-recommendations-for-prevention-diagnosis-and-therapy
#15
REVIEW
William D Rawlinson, Suresh B Boppana, Karen B Fowler, David W Kimberlin, Tiziana Lazzarotto, Sophie Alain, Kate Daly, Sara Doutré, Laura Gibson, Michelle L Giles, Janelle Greenlee, Stuart T Hamilton, Gail J Harrison, Lisa Hui, Cheryl A Jones, Pamela Palasanthiran, Mark R Schleiss, Antonia W Shand, Wendy J van Zuylen
Congenital cytomegalovirus is the most frequent, yet under-recognised, infectious cause of newborn malformation in developed countries. Despite its clinical and public health importance, questions remain regarding the best diagnostic methods for identifying maternal and neonatal infection, and regarding optimal prevention and therapeutic strategies for infected mothers and neonates. The absence of guidelines impairs global efforts to decrease the effect of congenital cytomegalovirus. Data in the literature suggest that congenital cytomegalovirus infection remains a research priority, but data are yet to be translated into clinical practice...
March 10, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28274169/safety-and-efficacy-of-topiramate-in-neonates-with-hypoxic-ischemic-encephalopathy-treated-with-hypothermia-neonati-a-feasibility-study
#16
Luca Filippi, Patrizio Fiorini, Serena Catarzi, Elettra Berti, Letizia Padrini, Elisa Landucci, Gianpaolo Donzelli, Laura Bartalena, Erika Fiorentini, Antonio Boldrini, Matteo Giampietri, Rosa Teresa Scaramuzzo, Giancarlo la Marca, Maria Luisa Della Bona, Simona Fiori, Francesca Tinelli, Ada Bancale, Andrea Guzzetta, Giovanni Cioni, Tiziana Pisano, Melania Falchi, Renzo Guerrini
Purpose To investigate the feasibility of a study based on treatment with topiramate added to moderate hypothermia in newborns with hypoxic ischemic encephalopathy (HIE). Materials and methods Multicenter randomized controlled trial. Term newborns with precocious metabolic, clinical and electroencephalographic (EEG) signs of HIE were selected according to their amplified integrated EEG pattern and randomized to receive either topiramate (10 mg/kg once a day for the first three days of life) plus moderate hypothermia or hypothermia alone...
March 8, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28273057/the-association-of-accessory-auricular-tissue-with-solid-organ-abnormalities-and-its-effect-on-auditory-and-vestibular-function
#17
Hillary E Jenny, Benjamin B Massenburg, E Hope Weissler, Peter J Taub
BACKGROUND: Accessory auricular tissue is a common congenital anomaly ranging from an accessory skin appendage to a separate pinna. The association between auditory or vestibular dysfunction and accessory auricular tissue is debated, and little is known about related solid organ abnormalities. We examine the prevalence of accessory auricular tissue, its association between solid organ abnormalities and auditory/vestibular dysfunction, and its management. METHODS: A retrospective cohort study was performed using the 2000 to 2012 HCUP kids' inpatient database...
April 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28257528/service-delivery-to-children-with-mild-hearing-loss-current-practice-patterns-and-parent-perceptions
#18
Elizabeth A Walker, Meredith Spratford, Sophie E Ambrose, Lenore Holte, Jacob Oleson
Purpose: This study investigates clinical practice patterns and parent perception of intervention for children with mild hearing loss (HL). Method: Ages at and delays between service delivery steps (first diagnostic evaluation, confirmation of HL, hearing aid [HA] fitting, entry into early intervention) were investigated for 113 children with mild HL. Comparisons were made to children with moderate-to-severe HL. Parents of children with mild HL reported reasons for delays and their perceptions of intervention and amplification for their children...
March 2, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/28244580/evolution-of-italian-universal-newborn-hearing-screening-programs
#19
L Bubbico, G Tognola, F Grandori
BACKGROUND: The aim of this study was to evaluate the state of implementation of the Universal Newborn Hearing Screening Programs in Italy and to determine the effect that an ad hoc legislation may have on the percentage of infants screened for detection of hearing impairment in nurseries. MATERIAL AND METHODS: Italian Newborn Hearing Screening data were obtained during four national surveys (years 2003, 2006, 2008, and 2011). The screening rates obtained by the Regions which adopted or did not adopt a legislation to increase the newborns' coverage were compared...
March 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/28241207/literacy-outcomes-for-primary-school-children-who-are-deaf-and-hard-of-hearing-a-cohort-comparison-study
#20
Margaret Harris, Emmanouela Terlektsi, Fiona E Kyle
Purpose: In this study, we compared the language and literacy of two cohorts of children with severe-profound hearing loss, recruited 10 years apart, to determine if outcomes had improved in line with the introduction of newborn hearing screening and access to improved hearing aid technology. Method: Forty-two children with deafness, aged 5-7 years with a mean unaided loss of 102 DB, were assessed on language, reading, and phonological skills. Their performance was compared with that of a similar group of 32 children with deafness assessed 10 years earlier and also a group of 40 children with normal hearing of similar single word reading ability...
March 1, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
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