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Pediatric hearing loss

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https://www.readbyqxmd.com/read/27925622/relation-between-amniotic-fluid-infection-or-cytokine-levels-and-hearing-screen-failure-in-infants-at-32-wk-gestation-or-less
#1
Eun Young Jung, Byung Yoon Choi, Jihye Rhee, Jaehong Park, Soo-Hyun Cho, Kyo Hoon Park
BACKGROUND: To determine whether the presence of intra-amniotic infection and elevated proinflammatory cytokine levels in amniotic fluid (AF) are associated with failure in the newborn hearing screen (NHS) test in very preterm neonates. METHODS: This is a retrospective cohort study of 112 premature singleton neonates born to women with preterm labor or preterm premature rupture of membranes at ≤32 wk. AF obtained through amniocentesis was cultured, and interleukin-6 (IL-6) and IL-8 levels were determined...
December 7, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27894912/hearing-thresholds-at-high-frequency-in-patients-with-cystic-fibrosis-a-systematic-review
#2
Debora T M Caumo, Lúcia B Geyer, Adriana R Teixeira, Sérgio S M Barreto
INTRODUCTION: High-frequency audiometry may contribute to the early detection of hearing loss caused by ototoxic medications. Many ototoxic drugs are widely used in the treatment of patients with cystic fibrosis. Early detection of hearing loss should allow known harmful drugs to be identified before the damage affects speech frequencies. The damage caused by ototoxicity is irreversible, resulting in important social and psychological consequences. In children, hearing loss, even when restricted to high frequencies, can affect the development of language...
November 9, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27886419/functional-characterization-of-a-novel-loss-of-function-mutation-of-prps1-related-to-early-onset-progressive-nonsyndromic-hearing-loss-in-koreans-dfnx1-potential-implications-on-future-therapeutic-intervention
#3
So Young Kim, Ah Reum Kim, Nayoung K D Kim, Chung Lee, Jin Hee Han, Min Young Kim, Eun-Hee Jeon, Woong-Yang Park, Rahul Mittal, Denise Yan, Xue Zhong Liu, Byung Yoon Choi
BACKGROUND: The symptoms of phosphoribosyl pyrophosphate synthetase 1 (PRPS1) deficiency diseases have been reported to be alleviated by medication. Herein, we report biochemical data to favor PRPS1 deficiency-related hearing loss as a potential target for pharmaceutical treatment. METHODS: We recruited 42 probands from subjects under the age of 15 years with a moderate degree of nonsyndromic autosomal-recessive or sporadic sensorineural hearing loss (SNHL) in at least one side...
November 25, 2016: Journal of Gene Medicine
https://www.readbyqxmd.com/read/27885978/factors-affecting-daily-cochlear-implant-use-in-children-datalogging-evidence
#4
Vijayalakshmi Easwar, Joseph Sanfilippo, Blake Papsin, Karen Gordon
BACKGROUND: Children with profound hearing loss can gain access to sound through cochlear implants (CIs), but these devices must be worn consistently to promote auditory development. Although subjective parent reports have identified several factors limiting long-term CI use in children, it is also important to understand the day-to-day issues which may preclude consistent device use. In the present study, objective measures gathered through datalogging software were used to quantify the following in children: (1) number of hours of CI use per day, (2) practical concerns including repeated disconnections between the external transmission coil and the internal device (termed "coil-offs"), and (3) listening environments experienced during daily use...
November 2016: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/27885975/hearing-benefit-and-rated-satisfaction-in-children-with-unilateral-conductive-hearing-loss-using-a-transcutaneous-magnetic-coupled-bone-conduction-hearing-aid
#5
Melissa J Polonenko, Lora Carinci, Karen A Gordon, Blake C Papsin, Sharon L Cushing
BACKGROUND: Bilateral hearing is important for learning, development, and function in complex everyday environments. Children with conductive and mixed hearing loss (HL) have been treated for years with percutaneous coupling through an abutment, which achieves powerful output, but the implant site is susceptible to skin reactions and trauma. To overcome these complications, transcutaneous magnetic coupling systems were recently introduced. PURPOSE: The purpose of the study was to evaluate whether the new transcutaneous magnetic coupling is an effective coupling paradigm for bone-conduction hearing aids (BCHAs)...
November 2016: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/27863639/conversion-of-traditional-osseointegrated-bone-anchored-hearing-aids-to-the-baha-%C3%A2-attract-in-four-pediatric-patients
#6
Elizabeth Cedars, Dylan Chan, Anga Lao, Lauren Hardies, Anna Meyer, Kristina Rosbe
Bone-anchored hearing aids are external devices attached to the skull via a titanium implant, and can be used for multiple types of hearing loss. Traditionally, osseointegrated implants have been coupled to the external processor with a percutaneous abutment, but more recently, a fully implanted, transcutaneous magnet-based system has become available. Skin reactions from the percutaneous portion are a common complication that can prevent use of the device during critical windows of language development and learning in children...
December 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27818398/early-identification-of-infants-and-toddlers-with-deafblindness
#7
Tanni L Anthony
Data from the 2014 National Center on Deaf-Blindness Count show that fewer than 100 infants and toddlers are currently identified with deaf-blindness across the United States and that identification rates for this population vary greatly from state to state. The author presents a key rationale for timely and accurate identification of early-onset deafblindness and of the challenges involved in current early identification practices. Health and educational providers play a vital role in efforts to understand the impact of deafblindness on early development, high-risk conditions, and diagnoses associated with pediatric deafblindness, as well as the warning signs of early-onset hearing and vision loss...
2016: American Annals of the Deaf
https://www.readbyqxmd.com/read/27787647/pediatric-intracranial-clear-cell-meningioma-a-clinicopathological-study-of-seven-cases-and-literature-review
#8
Hao Li, Meng Zhao, Yuming Jiao, Zhicen Li, Ji Ma, Shuo Wang, Yong Cao, Jizong Zhao
BACKGROUND: In this study, we reported seven cases of pediatric intracranial clear cell meningiomas (CCMs) in our institution and reviewed the relevant literature to investigate the clinicopathological characteristics, treatment options, and prognosis of these rare tumors. METHODS: From January 2005 to June 2016, we retrospectively reviewed seven pediatric intracranial CCMs in terms of their clinical data, preoperative MRI features, and prognosis. Moreover, a critical review of the English language literature was also conducted...
October 27, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27779564/x-linked-malformation-and-cochlear-implantation
#9
Henrik Smeds, Jeremy Wales, Filip Asp, Ulrika Löfkvist, Babak Falahat, Britt-Marie Anderlid, Lena Anmyr, Eva Karltorp
OBJECTIVE: To evaluate if cochlear implantation is safe and constitutes an option for hearing rehabilitation of children with x-linked inner ear malformation. STUDY DESIGN: Retrospective patient review in combination with a multidisciplinary follow-up. SETTING: Tertiary referral hospital and cochlear implant program. PATIENTS: Ten children with severe-profound mixed hearing loss and radiological findings consistent with Incomplete Partition type 3 cochlear malformation received cochlear implants during the years 2007 to 2015...
October 21, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27774600/characteristics-of-tinnitus-in-adolescents-and-association-with-psychoemotional-factors
#10
So Young Kim, Yung Jin Jeon, Jun-Young Lee, Young Ho Kim
OBJECTIVES/HYPOTHESIS: The characteristics and underlying mechanisms of tinnitus remain more elusive in the pediatric population than in adults. We investigated the prevalence of tinnitus, its characteristics, and associated factors, with a focus on psychoemotional problems in adolescents. STUDY DESIGN: Cross-sectional study METHODS: In total, 962 adolescents were surveyed for tinnitus and possibly related otologic and socioeconomic factors. The participants completed a visual analog scale (VAS) pertaining to various aspects of tinnitus, as well as the Tinnitus Handicap Inventory, Children's Depression Inventory (CDI), State Anxiety Inventory for Children, Trait Anxiety Inventory for Children (TAIC), Internet Addiction Test, Conners' Abbreviated Parent Rating Scale, and a learning disability score...
October 24, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27761737/middle-ear-adenoma-with-neuroendocrine-differentiation-a%C3%A2-pediatric-case-report
#11
Elisabeth Sterrer, Franz Windisch, Kurt Frey, Klaus Rettensteiner, Benjamin Loader
BACKGROUND: Middle ear adenoma with neuroendocrine differentiation (MEA-ND), also known as carcinoid tumor of the middle ear, is an extremely rare neoplasm, especially when located within the tympanic cavity. To the best of our knowledge, this represents the first pediatric case of a MEA-ND described in Europe. Excluding the present case, only three other pediatric cases of this disease have been published globally. CASE REPORT: We report on a 15-year-old female patient who presented with conductive hearing loss of the right ear...
October 19, 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/27755357/cochleariform-process-abutment-on-tbct-in-early-congenital-cholesteatoma
#12
Chang Ho Lee, So Young Kim, Hyoung-Mi Kim, Young Ju Kim, Ji Yoon Kim, Mi Kyung Kim
OBJECTIVES: To study the influence of the cochleariform process abutment (CPA) of early congenital cholesteatomas (CC) (ECCs) on surgical outcomes. STUDY DESIGN: Retrospective case review. SETTING: University hospital otology referral clinic. PATIENTS: Two hundred consecutive pediatric ECC patients. INTERVENTIONS: The patients were classified into three groups based on the temporal bone computed tomography (TBCT) findings of ECC: A) the absence of CPA, B) the presence of CPA, and C) the presence of CPA and extension posterior to the malleus handle...
October 12, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27729150/hearing-devices-for-children-with-unilateral-hearing-loss-patient-and-parent-reported-perspectives
#13
Patricia L Purcell, Rose Jones-Goodrich, Meghan Wisneski, Todd C Edwards, Kathleen C Y Sie
OBJECTIVE: Management of children with unilateral hearing loss is not standardized. The primary goal of this study was to elicit patient- and parent-reported perspectives regarding usage of hearing devices in pediatric UHL and to suggest a basic algorithmic approach to management. METHODS: Our tertiary care center recruited families of youth ages 5-19 years with unilateral hearing loss from January 2014 through October 2015. Parents of all youths completed a 36-item survey, and some youth ages 11-19 years participated in hour-long interviews...
November 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27729144/international-pediatric-otolaryngology-group-ipog-consensus-recommendations-hearing-loss-in-the-pediatric-patient
#14
Bryan J Liming, John Carter, Alan Cheng, Daniel Choo, John Curotta, Daniela Carvalho, John A Germiller, Stephen Hone, Margaret A Kenna, Natalie Loundon, Diego Preciado, Anne Schilder, Brian J Reilly, Stephane Roman, Julie Strychowsky, Jean-Michel Triglia, Nancy Young, Richard J H Smith
OBJECTIVE: To provide recommendations for the workup of hearing loss in the pediatric patient. METHODS: Expert opinion by the members of the International Pediatric Otolaryngology Group. RESULTS: Consensus recommendations include initial screening and diagnosis as well as the workup of sensorineural, conductive and mixed hearing loss in children. The consensus statement discusses the role of genetic testing and imaging and provides algorithms to guide the workup of children with hearing loss...
November 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27688594/the-p1-biomarker-for-assessing-cortical-maturation-in-pediatric-hearing-loss-a-review
#15
Anu Sharma, Hannah Glick, Emily Deeves, Erin Duncan
We review evidence for a high degree of neuroplasticity of the central auditory pathways in early childhood, citing evidence of studies of the P1 and N1 cortical auditory evoked potentials in congenitally deaf children receiving cochlear implants at different ages during childhood, children with auditory neuropathy spectrum disorder and children with hearing loss and comorbid multiple disabilities. We discuss neuroplasticity, including cortico-cortical de-coupling and cross-modal re-organization that occurs in deafness...
December 2015: Otorinolaringologia
https://www.readbyqxmd.com/read/27675353/predicting-iq-and-the-risk-of-hearing-loss-following-proton-versus-photon-radiation-therapy-for-pediatric-brain-tumor-patients
#16
D Fortin, A Ng, D S C Tsang, M B Sharpe, N J Laperriere, D Hodgson
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27669661/medical-interventions-for-the-prevention-of-platinum-induced-hearing-loss-in-children-with-cancer
#17
Jorrit W van As, Henk van den Berg, Elvira C van Dalen
BACKGROUND: Platinum-based therapy, including cisplatin, carboplatin, oxaliplatin or a combination of these, is used to treat a variety of paediatric malignancies. One of the most important adverse effects is the occurrence of hearing loss or ototoxicity. In an effort to prevent this ototoxicity, different otoprotective medical interventions have been studied. This review is the second update of a previously published Cochrane review. OBJECTIVES: To assess the efficacy of medical interventions to prevent hearing loss and to determine possible effects of these interventions on anti-tumour efficacy, toxicities other than hearing loss and quality of life in children with cancer treated with platinum-based therapy...
September 27, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27650356/long-term-auditory-complications-after-childhood-cancer-a-report-from-the-swiss-childhood-cancer-survivor-study
#18
Annette Weiss, Grit Sommer, Rahel Kasteler, Katrin Scheinemann, Michael Grotzer, Martin Kompis, Claudia E Kuehni
BACKGROUND: Auditory complications are an adverse event of childhood cancer treatment, especially common in children treated with platinum chemotherapy or cranial radiation. Variation between diagnostic childhood cancer groups has rarely been studied, and we do not know if the burden of auditory complications has changed over the last decades. PROCEDURE: Within the Swiss Childhood Cancer Survivor Study, we sent a questionnaire to all survivors who were diagnosed at age 16 years or less between 1976 and 2005...
September 21, 2016: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/27638585/clinical-electrophysiological-and-biochemical-markers-of-peripheral-and-central-nervous-system-disease-in-canine-globoid-cell-leukodystrophy-krabbe-s%C3%A2-disease
#19
Allison M Bradbury, Jessica H Bagel, Xuntian Jiang, Gary P Swain, Maria L Prociuk, Caitlin A Fitzgerald, Patricia A O'Donnell, Kyle G Braund, Daniel S Ory, Charles H Vite
Globoid cell leukodystrophy (GLD), or Krabbe's disease, is a debilitating and always fatal pediatric neurodegenerative disease caused by a mutation in the gene encoding the hydrolytic enzyme galactosylceramidase (GALC). In the absence of GALC, progressive loss of myelin and accumulation of a neurotoxic substrate lead to incapacitating loss of motor and cognitive function and death, typically by 2 years of age. Currently, there is no cure. Recent convincing evidence of the therapeutic potential of combining gene and cell therapies in the murine model of GLD has accelerated the requirement for validated markers of disease to evaluate therapeutic efficacy...
November 2016: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27636391/incidence-of-pediatric-superior-semicircular-canal-dehiscence-and-inner-ear-anomalies-a-large-multicenter-review
#20
Eric M Sugihara, Seilesh C Babu, Dennis J Kitsko, Michael S Haupert, Prasad J Thottam
OBJECTIVE: To determine the pediatric incidence and association of superior semicircular canal dehiscence (SSCD) with inner ear (IE) anomalies. STUDY DESIGN: Retrospective chart review. SETTING: Two tertiary referral centers. PATIENTS: Children less than 18 years who received a 0.5 mm or less collimated computed tomography study including the temporal bones between 2010 and 2013 for reasons including, but not limited to, hearing loss, trauma, and infection...
October 2016: Otology & Neurotology
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