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Tendon healing

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https://www.readbyqxmd.com/read/29775802/nonoperative-management-of-a-severe-proximal-rectus-femoris-musculotendinous-injury-in-a-recreational-athlete-a-case-report
#1
Park Ck, Zlomislic V, Du J, Huang Bk, Chang Ey, Chang Dg
This report describes a severe injury to the proximal rectus femoris (RF) muscle in a 37-year-old recreational athlete. This injury is a relatively rare occurrence in both the general and elite athletic populations. Acute and long-term imaging and functional outcomes are described. This athlete was able to return to full activity without surgical intervention. Follow-up imaging demonstrated gross healing of both complete (or near complete) muscle and tendon tears.
May 15, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29772995/bilateral-spontaneous-quadriceps-tendon-ruptures-after-staged-bilateral-total-knee-arthroplasties-a-case-report
#2
Marine Coste, Jared M Newman, Neil V Shah, Ahmed M Eldib, Preston W Grieco, Aditya V Maheshwari
Quadriceps tendon ruptures are rare complications of total knee arthroplasty (TKA) and may be associated with preexisting tendon degeneration, vascular injuries during surgery, damage to the quadriceps tendon with over resection of the patella, or incomplete healing after a particular surgical approach. Moreover, postoperative causes include tissue necrosis due to component malalignment, trauma, and infection. Patient factors such as chronic systemic diseases, medications, increased body weight, and sedentary lifestyle could also be responsible...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29767810/a-novel-remaining-tendon-preserving-repair-technique-leads-to-improved-outcomes-in-special-rotator-cuff-tear-patterns
#3
Yoon Sang Jeon, Rag Gyu Kim, Sang-Jin Shin
INTRODUCTION: The purpose of this study was to identify the tear pattern that could be anatomically repaired by preserving the remaining tendon on footprint and evaluate clinical outcomes of patients who underwent remaining tendon preserving cuff repair. MATERIALS AND METHODS: Of 523 patients with full-thickness rotator cuff tears who underwent arthroscopic repair, 41 (7.8%) patients had repairable rotator cuff tear while preserving the remaining tendon. Among them, 31 patients were followed-up for more than 2 years, including 26 patients with posterior L-shaped tear and 5 patients with transtendinous tear patterns...
May 16, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29765486/use-of-hyaluronic-acid-based-biological-bilaminar-matrix-in-wound-bed-preparation-a-case-series
#4
Richard Simman, Walid Mari, Sara Younes, Michael Wilson
Objective: Hyalomatrix, a matrix that consists of esterified hyaluronic acid, covered with a removable, semipermeable silicone top layer, was used to generate granulation tissue in a series of 12 serious, surgical wounds of different etiologies. Methods: Many defects showed exposed muscle, tendons, and/or bone. After thorough debridement, the matrix was applied, in a number of cases, combined with negative pressure wound therapy. Results: All wounds developed granulation tissue in and on top of the matrix. Nine wounds were then closed with a split skin autograft...
2018: Eplasty
https://www.readbyqxmd.com/read/29763339/the-v-shaped-distal-triceps-tendon-repair-a-comparative-biomechanical-analysis
#5
Bastian Scheiderer, Florian B Imhoff, Daichi Morikawa, Lucca Lacheta, Elifho Obopilwe, Mark P Cote, Andreas B Imhoff, Augustus D Mazzocca, Sebastian Siebenlist
BACKGROUND: Restoring footprint anatomy, minimizing gap formation, and maximizing the strength of distal triceps tendon repairs are essential factors for a successful healing process and return to sport. HYPOTHESIS: The novel V-shaped distal triceps tendon repair technique with unicortical button fixation closely restores footprint anatomy, provides minimal gap formation and high ultimate failure load, and minimizes iatrogenic fracture risk in acute/subacute distal triceps tendon tears...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29755840/treatment-of-mallet-finger-deformity-with-a-modified-palmaris-longus-tendon-graft-through-a-bone-tunnel
#6
Zengbing Liu, Kai Ma, Dong Huang
OBJECTIVE: To investigate the clinical effect of treating mallet finger deformity using a modified palmaris longus tendon graft through a bone tunnel. METHODS: Altogether, 21 patients with mallet finger deformity (16 men, 5 women; average age 31 years, range 19-47 years) were treated with a modified palmaris longus tendon graft through a bone tunnel during 18 months (2014-2016). Four index fingers, seven middle fingers, eight ring fingers, and two little fingers were treated for four cutting injuries, eleven finger sprains, four crush injuries, and two twist injuries (7 open and 14 closed injuries)...
2018: International Journal of Burns and Trauma
https://www.readbyqxmd.com/read/29753900/dorsal-longitudinal-t-myelotomy-bischof-ii-technique-a-useful-antiquated-procedure-for-treatment-of-intractable-spastic-paraplegia
#7
Bunpot Sitthinamsuwan, Inthira Khampalikit, Luckchai Phonwijit, Akkapong Nitising, Sarun Nunta-Aree, Sirilak Suksompong
OBJECTIVE: Dorsal longitudinal T-myelotomy is a long-established operation to treat severe spastic paraplegia. The present study aimed to report this surgical technique and investigate the efficacy of T-myelotomy for spasticity relief. METHODS: All cases undergoing T-myelotomy for treatment of intractable spastic paraplegia during 2009-2017 were included. The spasticity severity was evaluated using the Modified Ashworth Scale (MAS), Penn Spasm Frequency Scale (PSFS), Adductor Tone Rating Scale (ATRS), degree of passive range of motion (PROM), and occurrence of abdominal muscle spasms...
May 10, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29753179/endoscopic-achilles-tendon-shortening
#8
T H Lui
Healing in continuity with lengthening of the Achilles tendon is a disabling complication after Achilles tendon rupture. This results in weakness of ankle plantarflexion and a non-propulsive gait on the affected side. The elongated tendon may have to be shortened or reconstructed to re-establish the length and the physiologic tension in triceps surae muscle and allow restoration of push off. This technical note describes the details of endoscopic shortening of the Achilles tendon.
December 29, 2017: Foot
https://www.readbyqxmd.com/read/29746144/effects-of-allogenic-dermal-fibroblasts-on-rotator-cuff-healing-in-a-rabbit-model-of-chronic-tear
#9
Jieun Kwon, Yun Hee Kim, Sung-Min Rhee, Tae In Kim, Jimin Lee, Saewha Jeon, Joo Han Oh
BACKGROUND: The failure of rotator cuffs to heal after repair is an unresolved surgical issue. There have been substantial efforts, including the use of biological supplements, to enhance tendon healing. Dermal fibroblasts are a good candidate for tendon tissue engineering because they are similar to the tenocytes used for collagen synthesis. In addition, they are easily accessible because autologous dermal fibroblasts can be obtained from individual skin without major skin defects and allogenic dermal fibroblasts (ADFs) have already been commercialized in the field of skin engineering...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29744878/photochemical-tissue-bonding-promotes-the-proliferation-and-migration-of-injured-tenocytes-through-ros-rhoa-nf-%C3%AE%C2%BAb-dynamin-2-signaling-pathway
#10
Zuochao Yao, Xi Wang, Wen Zhang, Yushu Liu, Tao Ni
Photochemical tissue bonding (PTB) has been found to promote the healing of Achilles tendon tissue injury and to reduce postoperative complications. However, the underlying cellular and molecular mechanisms are not clear. In this study, the cell proliferation, ROS generation, migration and the protein expression of DNM2, NF-κB p65, TGF-β1 and VEGF in tenocytes after PTB treatment were measured by CCK-8, flow cytometry, Transwell and western blot assay, respectively. And those in tenocytes after DNM2 silencing or overexpressing or treatment with inhibitors of NF-κB, ROS and RhoA were also measured...
May 10, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29741923/effect-of-intraoperative-platelet-rich-plasma-treatment-on-postoperative-donor-site-knee-pain-in-patellar-tendon-autograft-anterior-cruciate-ligament-reconstruction-a-double-blind-randomized-controlled-trial
#11
Brian L Walters, David A Porter, Sarah J Hobart, Benjamin B Bedford, Daniel E Hogan, Malachy M McHugh, Devon A Klein, Kendall Harousseau, Stephen J Nicholas
BACKGROUND: Donor site morbidity in the form of anterior knee pain is a frequent complication after bone-patellar tendon-bone (BPTB) autograft anterior cruciate ligament (ACL) reconstruction. Hypothesis/Purpose: The purpose was to examine the effect of the intraoperative administration of platelet-rich plasma (PRP) on postoperative kneeling pain. It was hypothesized that PRP treatment would reduce knee pain. STUDY DESIGN: Randomized controlled trial; Level of evidence, 2...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29741808/intravoxel-incoherent-motion-ivim-imaging-in-human-achilles-tendon
#12
Kenneth Wengler, Takeshi Fukuda, Dharmesh Tank, Mingqian Huang, Elaine S Gould, Mark E Schweitzer, Xiang He
BACKGROUND: Limited microcirculation has been implicated in Achilles tendinopathy and may affect healing and disease progression. Existing invasive and noninvasive approaches to evaluate tendon microcirculation lack sensitivity and spatial coverage. PURPOSE: To develop a novel Achilles tendon intravoxel incoherent motion (IVIM) MRI protocol to overcome the limitations from low tendon T2 /T2 * value and low intratendinous blood volume and blood velocity to evaluate tendon microcirculation...
May 9, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29732609/diffusion-tensor-imaging-of-human-achilles-tendon-by-stimulated-echo-readout-segmented-epi-ste-rs-epi
#13
Kenneth Wengler, Dharmesh Tank, Takeshi Fukuda, James M Paci, Mingqian Huang, Mark E Schweitzer, Xiang He
PURPOSE: Healing, regeneration, and remodeling of the injured Achilles tendon are associated with notable changes in tendon architecture. However, assessing Achilles microstructural properties with conventional diffusion tension imaging (DTI) remains a challenge because of very short T2 / T2* values of the tendon. Hence, the objective of this study was to develop a novel Achilles tendon DTI protocol for a non-invasive investigation of the changes of microstructural integrity in tendinopathy...
May 6, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29730212/arthroscopic-incomplete-repair-using-a-hybrid-technique-for-large-to-massive-rotator-cuff-tears-clinical-results-and-structural-integrity
#14
Jeung Yeol Jeong, Young Cheol Yoon, Sang Min Lee, Jae Chul Yoo
PURPOSE: The first aim of this study was to introduce the concept of hybrid repair (incomplete repair) for large to massive rotator cuff tears and to report clinical results and structural integrity of patients with a minimum 2-year follow-up. The second aim was to compare arthroscopic hybrid repair with partial repair for large to massive rotator cuff tears. METHODS: We retrospectively evaluated 65 patients who underwent arthroscopic incomplete (hybrid) repair (45 patients) or partial repair (20 patients) for large to massive cuff tears from March 2011 to January 2015...
May 2, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29725765/treatment-of-acute-achilles-tendon-rupture-with-a-standardised-protocol
#15
Heidi Haapasalo, Ulla Peltoniemi, Heikki-Jussi Laine, Pekka Kannus, Ville M Mattila
INTRODUCTION: A treatment protocol favouring non-operative treatment and based on early weight-bearing and early range-of-motion exercises was implemented in standard clinical care of a level I trauma clinic. MATERIALS AND METHODS: All patients treated due to acute Achilles tendon rupture between 2008 and 2014 were included in the study (n = 411). The patient records were retrospectively evaluated. RESULTS: The mean age of patients was 47 (range 17-88) years...
May 3, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29722765/making-them-commit-strategies-to-influence-phenotypic-differentiation-in-mesenchymal-stem-cells
#16
Alessio Giai Via, Mary B McCarthy, Laura de Girolamo, Enrico Ragni, Francesco Oliva, Nicola Maffulli
Tendon injuries, bone defects, and cartilage defects are complex clinical conditions leading to pain and dysfunctions. Tendon, bone, and cartilage are highly specialized and organized tissues, and the self-healing may be limited by their histologic features, or impaired by the local conditions. Furthermore, the resultant tissue often shows inferior properties compared with native tissue, leading to high rates of reruptures and revision surgeries. A growing field of research has explored tendon, bone, and cartilage regeneration using mesenchymal stem cells (MSCs), because of their multipotency, and because they are relatively easy to harvest...
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722763/cell-therapies-in-tendon-ligament-and-musculoskeletal-system-repair
#17
Pilar M de Albornoz, Rocco Aicale, Francisco Forriol, Nicola Maffulli
In the last few decades, several techniques have been used to optimize tendon, ligament, and musculoskeletal healing. The evidence in favor of these techniques is still not proven, and level I studies are lacking. We performed an analysis of the therapeutic strategies and tissue engineering projects recently published in this field. Here, we try to give an insight into the current status of cell therapies and the latest techniques of bioengineering applied to the field of orthopedic surgery. The future areas for research in the management of musculoskeletal injuries are outlined...
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722762/prp-as-an-adjunct-to-rotator-cuff-tendon-repair
#18
F Alan Barber
Arthroscopic rotator cuff repair is a commonly performed repair. Technical developments provide surgeons the tools to create biomechanically robust repairs. How can the biological response mirror the strong and stable surgery? Platelet-rich plasma (PRP) is a supraphysiological platelet concentration which may positively augment rotator cuff healing. Not all PRPs are the same. High leukocyte levels and thrombin activation may be detrimental to tendon healing. Thrombin activation triggers an immediate release of growth factors and may actually inhibit some parts of the healing response...
June 2018: Sports Medicine and Arthroscopy Review
https://www.readbyqxmd.com/read/29722123/a-tricalcium-phosphate-polyether-ether-ketone-anchor-bionic-fixation-device-for-anterior-cruciate-ligament-reconstruction-safety-and-efficacy-in-a-beagle-model
#19
Genwen Mao, Zili Qin, Zheng Li, Xiang Li, Yusheng Qiu, Weiguo Bian
The goal of this study was to develop a bionic fixation device based on the use of a tricalcium phosphate/polyether ether ketone anchor and harvesting of the ulnar carpal flexor muscle tendon for application as a ligament graft in a beagle anterior cruciate ligament (ACL) reconstruction model, with the goal of accelerating the ligament graft-to-bone tunnel healing and providing a robust stability through exploration of this new kind of autologous ligament graft. The safety and efficacy of this fixation device were explored 3 and 6 months after surgery in a beagle ACL reconstruction model using biomechanical tests and comprehensive histological observation...
May 2, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29713352/chemical-activation-of-the-hypoxia-inducible-factor-reversibly-reduces-tendon-stem-cell-proliferation-inhibits-their-differentiation-and-maintains-cell-undifferentiation
#20
Alessandra Menon, Pasquale Creo, Marco Piccoli, Sonia Bergante, Erika Conforti, Giuseppe Banfi, Pietro Randelli, Luigi Anastasia
Adult stem cell-based therapeutic approaches for tissue regeneration have been proposed for several years. However, adult stem cells are usually limited in number and difficult to be expanded in vitro, and they usually tend to quickly lose their potency with passages, as they differentiate and become senescent. Culturing stem cells under reduced oxygen tensions (below 21%) has been proposed as a tool to increase cell proliferation, but many studies reported opposite effects. In particular, cell response to hypoxia seems to be very stem cell type specific...
2018: Stem Cells International
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