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https://www.readbyqxmd.com/read/28531908/methods-and-reporting-studies-assessing-fecal-microbiota-transplantation-a-systematic-review
#1
Aïda Bafeta, Amelie Yavchitz, Carolina Riveros, Rui Batista, Philippe Ravaud
Background: Fecal microbiota transplantation (FMT) could be a novel treatment option for several chronic diseases associated with altered gut microbiota. Purpose: To examine the conduct and reporting of studies assessing FMT. Data Sources: Cochrane Central Register of Controlled Trials, PubMed, EMBASE, and Web of Science from inception to 31 January 2017. Study Selection: Two reviewers independently examined titles and abstracts to identify all English-language reports of human clinical studies assessing the safety or efficacy of FMT...
May 23, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28531829/prevalence-of-gestational-diabetes-mellitus-in-europe-a-meta-analysis
#2
Claire E Eades, Dawn M Cameron, Josie M M Evans
AIMS: Estimates of the prevalence of gestational diabetes vary widely. It is important to have a clear understanding of the prevalence of this condition to be able to plan interventions and health care provision. This paper describes a meta-analysis of primary research data reporting the prevalence of gestational diabetes mellitus in the general pregnant population of developed countries in Europe. METHODS: Four electronic databases were systematically searched in May 2016...
May 9, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28531771/preventive-effect-of-l-carnitine-and-its-derivatives-on-endothelial-dysfunction-and-platelet-aggregation
#3
REVIEW
Mohammad Mohammadi, Azita Hajhossein Talasaz, Mohammad Alidoosti
BACKGROUND AND AIM: Oxidative stress plays an important role in platelet activation and endothelial dysfunction. Exogenous and endogenous reactive oxygen species are associated with platelet activation and vascular dysfunction. Antioxidants have been shown to attenuate oxidative stress and consequently endothelial dysfunction by preventing inflammation, regulating vascular tone, and promoting antiadhesive and antithrombotic properties. l-carnitine and its derivatives have been demonstrated to improve endothelial and platelet function against oxidative stress by several mechanisms, some of which cannot be found in other antioxidants...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28531179/the-gingival-vein-as-a-minimally-traumatic-site-for-multiple-blood-sampling-in-guinea-pigs-and-hamsters
#4
Mariana Valotta Rodrigues, Simone Oliveira de Castro, Cynthia Zaccanini de Albuquerque, Vânia Gomes de Moura Mattaraia, Marcelo Larami Santoro
Laboratory animals are still necessary in scientific investigation and vaccine testing, but while novel methodological approaches are not available for their replacement, the search for new, humane, easy, and painless methods is necessary to diminish their stress and pain. When multiple blood samples are to be collected from hamsters and guinea pigs, the number of available venipuncture sites-which are greatly diminished in these species in comparison with other rodents due to the absence of a long tail-, harasses animal caregivers and researchers...
2017: PloS One
https://www.readbyqxmd.com/read/28531109/physical-activity-and-quality-of-life-in-cancer-survivors-a-meta-synthesis-of-qualitative-research
#5
REVIEW
Shaunna Burke, Amanda Wurz, Andrew Bradshaw, Stephanie Saunders, Malcolm A West, Jennifer Brunet
Qualitative research on the impact of physical activity on quality of life (QoL) in adults diagnosed with cancer is accumulating. However, the field of physical activity and cancer survivorship lack a synthesis of this research to reliably understand the implications for future research and practice. The aim of this meta-synthesis was to identify, appraise, and synthesize qualitative research on cancer survivors' perspectives of the impact of physical activity on their QoL. Seven electronic databases were searched for original studies published in English, and reference lists of relevant studies were hand-searched to identify additional studies...
May 20, 2017: Cancers
https://www.readbyqxmd.com/read/28530624/-buccal-mucosa-graft-for-the-treatment-of-long-ureteral-stenosis-bibliographic-review
#6
Gema Del Pozo Jiménez, Ignacio Castillón-Vela, Joaquín Carballido Rodríguez
OBJECTIVE: To perform a literature review on the use of buccal mucosa graft (BMG) in the treatment of extensive ureteral stenosis, according to the criteria of Evidence Based Medicine. METHODS: Pubmed search of published studies with the following keywords: "ureteral stricture treatment", "buccal mucosa graft ureteral treatment" and "buccal mucosa graft ureteroplasty", without time limits, in English and Spanish; 12 articles were identified with a total of 48 cases (46 patients) of BMG use in ureteral repair...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28530045/mental-health-challenges-among-adolescents-living-with-hiv
#7
Rachel C Vreeman, Brittany M McCoy, Sonia Lee
INTRODUCTION: Mental health is a critical and neglected global health challenge for adolescents infected with HIV. The prevalence of mental and behavioural health issues among HIV-infected adolescents may not be well understood or addressed as the world scales up HIV prevention and treatment for adolescents. The objective of this narrative review is to assess the current literature related to mental health challenges faced by adolescents living with HIV, including access to mental health services, the role of mental health challenges during transition from paediatric to adult care services and responsibilities, and the impact of mental health interventions...
May 16, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28529532/the-effect-of-three-different-meditation-exercises-on-hypertension-a-network-meta-analysis
#8
Hongchang Yang, Xueping Wu, Min Wang
We aimed to use the pairwise and network meta-analysis to estimate the effects of different meditation exercises on the control of systolic blood pressure (SBP) and diastolic blood pressure (DBP). Randomized controlled trials (RCTs) were retrieved from PubMed and Embase up to June 2016, which are published in English and reported on meditation exercise for hypertensive patients. Risks of bias assessment of the included studies were assessed by Cochrane Collaboration Recommendations and network meta-analysis was performed by ADDIS...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28529262/investigations-of-carotid-stenosis-to-identify-vulnerable-atherosclerotic-plaque-and-determine-individual-stroke-risk
#9
Madieke I Liem, Fiona Kennedy, Leo H Bonati, Aad van der Lugt, Bram F Coolen, Aart J Nederveen, Hans R Jager, Martin M Brown, Paul J Nederkoorn
Selection of patients with atherosclerotic carotid stenosis for revascularization is mainly based on the degree of luminal narrowing of the carotid artery. However, identification of other features of plaque apart from the degree of stenosis could enable better selection for intervention if they are also associated with the occurrence of stroke. Before these risk factors can possibly play a role in treatment decisions, their prognostic value needs to be proven. The purpose of this narrative review is to summarize current knowledge regarding the risk factors for stroke in patients with carotid stenosis, how they can be determined, and to what extent they predict stroke, based on recent literature...
May 20, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28529246/surgical-outcome-of-laminoplasty-for-cervical-spondylotic-myelopathy-in-an-elderly-population-potentiality-for-effective-early-surgical-intervention-a-meta-analysis
#10
Yasuhiro Takeshima, Ryuta Matsuoka, Ichiro Nakagawa, Fumihiko Nishimura, Hiroyuki Nakase
A systematic review and meta-analysis was conducted to determine differences in surgical outcomes of laminoplasty for cervical spondylotic myelopathy (CSM) between elderly and non-elderly patients. PubMed and Google Scholar searches were performed using several key words and phrases related to cervical laminoplasty in elderly populations. Included studies were written in English, addressed laminoplasty for cervical spondylotic myelopathy, and evaluated outcomes of the treatment. Statistical analysis was performed using a random-effect model...
May 19, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/28529237/-i-life-in-the-year-6000-i-by-santiago-ram%C3%A3-n-y-cajal-a-translation-of-an-unpublished-vacation-story
#11
Andrew W Perez
In 2006, Laura Otis provided the first English translation of five short stories written by the Spanish artist, neuroscientist, and histologist Santiago Ramón y Cajal. These stories, originally published in 1905 by Cajal under the pseudonym "Dr. Bacteria," are called "Cuentos de vacaciones: narraciones seudocientíficas" or "Vacation Stories: Pseudoscientific Tales." In 1973, a version of Cajal's manuscript "La vida en el año 6000" (Life in the year 6000) was revealed. It had remained in manuscript form since the mid-1880s and appears to be a draft of one of Cajal's unpublished "Cuentos de vacaciones...
2017: Literature and Medicine
https://www.readbyqxmd.com/read/28529231/alzheimer-s-disease-metaphors-as-mirror-and-lens-to-the-stigma-of-dementia
#12
Martina Zimmermann
This essay gives an overview of the metaphors that patients in comparison to caregivers employ to conceptualize their experience with the chronic degenerative, cognitive, and incurable aspects of Alzheimer's disease. It explores how the images (such as the journey, darkness, the death sentence, and torture) relate to the narration of cognitive decline and memory loss, and how these personal accounts negotiate with the culturally dominant dementia narrative that centers on the patient's passivity and dependence and is, usually, found in caregiver stories...
2017: Literature and Medicine
https://www.readbyqxmd.com/read/28528561/angiotensin-ii-for-the-treatment-of-vasodilatory-shock
#13
Ashish Khanna, Shane W English, Xueyuan S Wang, Kealy Ham, James Tumlin, Harold Szerlip, Laurence W Busse, Laith Altaweel, Timothy E Albertson, Caleb Mackey, Michael T McCurdy, David W Boldt, Stefan Chock, Paul J Young, Kenneth Krell, Richard G Wunderink, Marlies Ostermann, Raghavan Murugan, Michelle N Gong, Rakshit Panwar, Johanna Hästbacka, Raphael Favory, Balasubramanian Venkatesh, B Taylor Thompson, Rinaldo Bellomo, Jeffrey Jensen, Stew Kroll, Lakhmir S Chawla, George F Tidmarsh, Adam M Deane
Background Vasodilatory shock that does not respond to high-dose vasopressors is associated with high mortality. We investigated the effectiveness of angiotensin II for the treatment of patients with this condition. Methods We randomly assigned patients with vasodilatory shock who were receiving more than 0.2 μg of norepinephrine per kilogram of body weight per minute or the equivalent dose of another vasopressor to receive infusions of either angiotensin II or placebo. The primary end point was a response with respect to mean arterial pressure at hour 3 after the start of infusion, with response defined as an increase from baseline of at least 10 mm Hg or an increase to at least 75 mm Hg, without an increase in the dose of background vasopressors...
May 21, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28528451/influence-of-comorbidity-on-chemotherapy-use-for-early-breast-cancer-systematic-review-and-meta-analysis
#14
REVIEW
Melissa J Edwards, Ian D Campbell, Ross A Lawrenson, Marion J Kuper-Hommel
PURPOSE: Patients with early breast cancer and coexistent comorbidities generally experience worse prognosis which may be in part related to inferior treatment. Randomised data on chemotherapy use and tolerance in comorbid patients are limited. We aimed to review the available literature regarding the use of chemotherapy in such patients. METHODS: A systematic search of databases was performed for English-language articles evaluating the impact of comorbidity on chemotherapy use for early breast cancer...
May 20, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28528416/time-trends-of-persistent-organic-pollutants-in-benthic-and-pelagic-indicator-fishes-from-puget-sound-washington-usa
#15
James E West, Sandra M O'Neill, Gina M Ylitalo
We modeled temporal trends in polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), and dichlorodiphenyltrichloroethane and its metabolites (DDTs) in two indicator fish species representing benthic and pelagic habitats in Puget Sound, Washington, USA. English sole (Parophrys vetulus, benthic) index sites and larger-scale Pacific herring (Clupea pallasii, pelagic) foraging areas represented a wide range of possible contamination conditions, with sampling locations situated adjacent to watersheds exhibiting high, medium and low development...
May 20, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28528396/penetration-of-vancomycin-into-the-cerebrospinal-fluid-a-systematic-review
#16
REVIEW
Jessica E Beach, Jerrold Perrott, Ricky D Turgeon, Mary H H Ensom
INTRODUCTION: Infectious disease and pharmacokinetic textbooks indicate that vancomycin has poor penetration into the central nervous system due to its hydrophilic nature and high molecular weight. Recent literature suggests that penetration of vancomycin into cerebrospinal fluid (CSF) is higher than previously reported; therefore, we conducted a systematic review to assess the penetration of vancomycin into CSF. METHODS: We searched the MEDLINE, EMBASE, and CENTRAL electronic databases for English-language human studies evaluating serum and CSF concentrations of intravenous vancomycin...
May 20, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28528198/on-national-flags-and-language-tags-effects-of-flag-language-congruency-in-bilingual-word-recognition
#17
Jonathan Grainger, Mathieu Declerck, Yousri Marzouki
French-English bilinguals performed a generalized lexical decision experiment with mixed lists of French and English words and pseudo-words. In Experiment 1, each word/pseudo-word was superimposed on the picture of the French or UK flag, and flag-word congruency was manipulated. The flag was not informative with respect to either the lexical decision response or the language of the word. Nevertheless, lexical decisions to word stimuli were faster following the congruent flag compared with the incongruent flag, but only for French (L1) words...
May 18, 2017: Acta Psychologica
https://www.readbyqxmd.com/read/28528076/systematic-review-can-non-mydriatic-cameras-accurately-detect-diabetic-retinopathy
#18
REVIEW
Chloe Bedard, Siying Sherry Liu, Christopher Patterson, Hertzel Gerstein, Lauren Griffith
AIMS: Diabetes puts many individuals at risk for developing diabetic retinopathy (DR). Non-mydriatic (NM) retinal photography without pharmacological pupil dilation can be used to detect DR, however, its value in a general clinical setting has not been established. The objective of this review is to evaluate the validity of NM retinal photos, as compared to the reference standard of seven standard stereoscopic 30 degree field photographs (7SF), for their use of detecting DR in community-dwelling adults...
May 10, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28527613/no-344-opportunistic-salpingectomy-and-other-methods-of-risk-reduction-for-ovarian-fallopian-tube-peritoneal-cancer-in-the-general-population
#19
Shannon Salvador, Stephanie Scott, Julie Ann Francis, Anita Agrawal, Christopher Giede
OBJECTIVE: This guideline reviews the potential benefits of opportunistic salpingectomy to prevent the development of high grade serous cancers (HGSC) of the ovary/fallopian tube/peritoneum based on current evidence supporting the fallopian tube origin of disease. INTENDED USERS: Gynaecologists, obstetricians, family doctors, registered nurses, nurse practitioners, residents, and health care providers. TARGET POPULATION: Adult women (18 and older): OPTIONS: Women considering hysterectomy who wish to retain their ovaries in situ have traditionally also retained their fallopian tubes...
June 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28527478/-translation-cultural-adaptation-and-validation-of-the-satisfaction-with-amplification-in-daily-life-scale-for-european-portuguese
#20
Luis Roque Dos Reis, Mariana Donato, Rita Sousa, Pedro Escada
INTRODUCTION: The scale Satisfaction with Amplification in Daily Life uses a simple and easily administered questionnaire to evaluate the adaptation of individuals to their hearing aids. The objective of this study is to validate the scale for European Portuguese speakers, by means of translation and cultural adaptation of the questionnaire. The study includes an evaluation of reproducibility and a description of the results of the administration of the questionnaire to patients fitted with hearing aids...
February 27, 2017: Acta Médica Portuguesa
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