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Schizophrenia hallucination

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https://www.readbyqxmd.com/read/29925851/trajectories-and-changes-in-individual-items-of-positive-and-negative-syndrome-scale-among-schizophrenia-patients-prior-to-impending-relapse
#1
Dai Wang, Srihari Gopal, Susan Baker, Vaibhav A Narayan
Effective early detection of impending relapse may offer opportunities for early interventions to prevent full relapse in schizophrenia patients. Previously reported early warning signs were not consistently validated by prospective studies. It remains unclear which symptoms are most predictive of relapse. To prioritize the symptoms to be captured by periodic self-report in technology-enabled remote assessment solutions for monitoring symptoms and detecting relapse early, we analyzed data from three relapse-prevention studies to identify individual items of the Positive and Negative Syndrome Scale (PANSS) that changed the most prior to relapse and to understand exactly when these symptoms manifested...
June 20, 2018: NPJ Schizophrenia
https://www.readbyqxmd.com/read/29914267/latent-schizencephaly-with-psychotic-phenotype-or-schizophrenia-with-schizencephaly-a-case-report-and-review-of-the-literature
#2
Filip Tylš, Martin Brunovský, Kateřina Šulcová, Barbora Kohútová, Zuzana Ryznarová, Miloslav Kopeček
OBJECTIVES: Although schizencephaly belongs to the class of neurodevelopmental disorders, which are a well-known predisposing factor for psychosis, there is a lack of relevant studies and diagnostic guidelines on this relationship. METHOD: A case report of first-episode psychosis with persistent negative symptoms associated with schizencephaly is described and compared with 7 other cases found in the literature. RESULTS: We found perinatal pathology, cognitive deficit, and EEG abnormality in a patient with atypical initial symptoms of psychosis such as olfactory hallucinations...
June 1, 2018: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/29909766/-phenomenology-clinical-diagnostics-and-treatment-of-hallucinations
#3
Daniela Hubl
Phenomenology, clinical diagnostics and treatment of hallucinations Abstract. Hallucinations are perceptions without any stimulus. They occur typically in schizophrenia, but they can be found in other psychiatric or medical disorders as well. Recently, hallucinations have been increasingly reported to occur with a high prevalence in the general population and they are conceptualised as continuum from a physiological to pathological especially psychotic phenomenon. Schizophrenic hallucinations exhibit a special proximity to language and for this they can be considered as diagnostic...
June 2018: Therapeutische Umschau. Revue Thérapeutique
https://www.readbyqxmd.com/read/29897597/high-frequency-neuronavigated-rtms-in-auditory-verbal-hallucinations-a-pilot-double-blind-controlled-study-in-patients-with-schizophrenia
#4
Sonia Dollfus, Nemat Jaafari, Olivier Guillin, Benoit Trojak, Marion Plaze, Ghassen Saba, Cécilia Nauczyciel, Aurélie Montagne Larmurier, Nathalie Chastan, Vincent Meille, Marie-Odile Krebs, Samar S Ayache, Jean Pascal Lefaucheur, Annick Razafimandimby, Elise Leroux, Rémy Morello, Jean Marie Batail, Perrine Brazo, Nicolas Lafay, Issa Wassouf, Ghina Harika-Germaneau, Remy Guillevin, Carole Guillevin, Emmanuel Gerardin, Maud Rotharmel, Benoit Crépon, Raphael Gaillard, Christophe Delmas, Gael Fouldrin, Guillaume Laurent, Clément Nathou, Olivier Etard
INTRODUCTION: Despite extensive testing, the efficacy of low-frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) of temporo-parietal targets for the treatment of auditory verbal hallucinations (AVH) in patients with schizophrenia is still controversial, but promising results have been reported with both high-frequency and neuronavigated rTMS. Here, we report a double-blind sham-controlled study to assess the efficacy of high-frequency (20 Hz) rTMS applied over a precise anatomical site in the left temporal region using neuronavigation...
April 6, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29897555/linked-4-way-multimodal-brain-differences-in-schizophrenia-in-a-large-chinese-han-population
#5
Shengfeng Liu, Haiying Wang, Ming Song, Luxian Lv, Yue Cui, Yong Liu, Lingzhong Fan, Nianming Zuo, Kaibin Xu, Yuhui Du, Qingbao Yu, Na Luo, Shile Qi, Jian Yang, Sangma Xie, Jian Li, Jun Chen, Yunchun Chen, Huaning Wang, Hua Guo, Ping Wan, Yongfeng Yang, Peng Li, Lin Lu, Hao Yan, Jun Yan, Huiling Wang, Hongxing Zhang, Dai Zhang, Vince D Calhoun, Tianzi Jiang, Jing Sui
Multimodal fusion has been regarded as a promising tool to discover covarying patterns of multiple imaging types impaired in brain diseases, such as schizophrenia (SZ). In this article, we aim to investigate the covarying abnormalities underlying SZ in a large Chinese Han population (307 SZs, 298 healthy controls [HCs]). Four types of magnetic resonance imaging (MRI) features, including regional homogeneity (ReHo) from resting-state functional MRI, gray matter volume (GM) from structural MRI, fractional anisotropy (FA) from diffusion MRI, and functional network connectivity (FNC) resulted from group independent component analysis, were jointly analyzed by a data-driven multivariate fusion method...
April 20, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29892215/transcranial-direct-current-stimulation-symptomatology-and-cognition-in-psychosis-a-qualitative-review
#6
REVIEW
Tina Gupta, Nicholas J Kelley, Andrea Pelletier-Baldelli, Vijay A Mittal
Schizophrenia is a chronic, debilitating condition that affects approximately 1% of the population. Individuals diagnosed with schizophrenia typically exhibit positive (e.g., hallucinations) and negative symptoms (e.g., anhedonia) and impairments in cognitive function. Given the limitations of antipsychotic medication and psychotherapy in fully treating psychosis symptomatology, there has been increasing interest in other interventions such as transcranial direct current stimulation (tDCS). tDCS is a non-invasive neuromodulation technique, that is safe, cost-effective, and widely accessible...
2018: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29883222/abnormal-regions-in-functional-connectivity-of-chronic-schizophrenia
#7
Bo Chen
OBJECTIVES: Schizophrenia is a predominant product of pathological alterations distributed throughout interconnected neural systems. Functional connections (FCs) methodology is an effective lever to investigate macroscopic neural activity patterns underlying critical aspects of cognition and behavior. However, region properties of brain architecture have been less investigated by special markers of dynamical graph in general mental disorders. METHODS: Embracing the eigenvector centrality in holism significance, our important process is to uncover noticeable edges and regions with antagonistic stance between morbid and normal FCs of 67 healthy controls (HCs) and 53 chronic schizophrenia patients (SZs)...
June 8, 2018: International Journal of Neuroscience
https://www.readbyqxmd.com/read/29867612/sexual-hallucinations-in-schizophrenia-spectrum-disorders-and-their-relation-with-childhood-trauma
#8
Jan Dirk Blom, Esmeralda Mangoenkarso
Background: Sexual hallucinations are probably the most neglected types of hallucination, even in psychiatric settings. They are often multimodal in nature, and their prevalence rate is unknown. For other types of hallucination, notably auditory hallucinations, childhood trauma is an important risk factor. However, whether this also applies to sexual hallucinations is unexplored. Objective: To establish the prevalence rate of sexual hallucinations in a clinical sample of patients diagnosed with a schizophrenia spectrum disorder, to describe their phenomenological characteristics, and to estimate their relationship with childhood trauma...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29863689/-psychopathology-and-phenomenology-of-religious-delusion-of-possession-in-schizophrenia
#9
G I Kopeyko, O A Borisova, E V Gedevani
AIM: To analyze psychopathological features of religious delusion of possession, determine the place of this phenomenon in psychotic syndrome, and identify the prognosis and dynamics of schizophrenia due to this disorder. MATERIAL AND METHODS: Thirteen patients with religious delusion of possession were examined in 1994-2016 by psychopathological and follow-up methods. RESULTS AND CONCLUSION: Hallucinations of a general feeling are the crucial psychopathological phenomenon of states with religious delusion of possession...
2018: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29859117/gabaergic-deficits-and-schizophrenia-like-behaviors-in-a-mouse-model-carrying-patient-derived-neuroligin-2-r215h-mutation
#10
Dong-Yun Jiang, Zheng Wu, Cody Tieu Forsyth, Yi Hu, Siu-Pok Yee, Gong Chen
Schizophrenia (SCZ) is a severe mental disorder characterized by delusion, hallucination, and cognitive deficits. We have previously identified from schizophrenia patients a loss-of-function mutation Arg215 →His215 (R215H) of neuroligin 2 (NLGN2) gene, which encodes a cell adhesion molecule critical for GABAergic synapse formation and function. Here, we generated a novel transgenic mouse line with neuroligin-2 (NL2) R215H mutation. The single point mutation caused a significant loss of NL2 protein in vivo, reduced GABAergic transmission, and impaired hippocampal activation...
June 1, 2018: Molecular Brain
https://www.readbyqxmd.com/read/29843003/interventions-to-reduce-stigma-towards-people-with-severe-mental-illness-systematic-review-and-meta-analysis
#11
REVIEW
Amy J Morgan, Nicola J Reavley, Anna Ross, Lay San Too, Anthony F Jorm
This review evaluates the evidence on what interventions are effective in reducing public stigma towards people with severe mental illness, defined as schizophrenia, psychosis or bipolar disorder. We included 62 randomised controlled trials of contact interventions, educational interventions, mixed contact and education, family psychoeducation programs, and hallucination simulations. Contact interventions led to small-to-medium reductions in stigmatising attitudes (d = 0.39, 95% CI: 0.22 to 0.55) and desire for social distance (d = 0...
May 23, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29802811/mirtazapine-adjunct-for-people-with-schizophrenia
#12
REVIEW
Luke A Perry, Dhruvesh Ramson, Suzanne Stricklin
BACKGROUND: Many individuals who have a diagnosis of schizophrenia experience a range of distressing and debilitating symptoms. These can include positive symptoms (such as delusions, hallucinations, disorganised speech), cognitive symptoms (such as trouble focusing or paying attention or using information to make decisions), and negative symptoms (such as diminished emotional expression, avolition, alogia, and anhedonia). Antipsychotic drugs are often only partially effective, particularly in treating negative symptoms, indicating the need for additional treatment...
May 26, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29790145/-nursing-experience-of-using-mirror-visual-feedback-for-a-schizophrenia-patient-with-visual-hallucinations
#13
Shu-Ling Lan, Yu-Chi Chen, Hsiu-Ju Chang
The aim of this paper was to describe the nursing application of mirror visual feedback in a patient suffering from long-term visual hallucinations. The intervention period was from May 15th to October 19th, 2015. Using the five facets of psychiatric nursing assessment, several health problems were observed, including disturbed sensory perceptions (prominent visual hallucinations) and poor self-care (e.g. limited abilities to self-bathe and put on clothing). Furthermore, "caregiver role strain" due to the related intense care burden was noted...
June 2018: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/29780332/myoclonic-jerks-and-schizophreniform-syndrome-case-report-and-literature-review
#14
Dominique Endres, Dirk-M Altenmüller, Bernd Feige, Simon J Maier, Kathrin Nickel, Sabine Hellwig, Jördis Rausch, Christiane Ziegler, Katharina Domschke, John P Doerr, Karl Egger, Ludger Tebartz van Elst
Background: Schizophreniform syndromes can be divided into primary idiopathic forms as well as different secondary organic subgroups (e.g., paraepileptic, epileptic, immunological, or degenerative). Secondary epileptic explanatory approaches have often been discussed in the past, due to the high rates of electroencephalography (EEG) alterations in patients with schizophrenia. In particular, temporal lobe epilepsy is known to be associated with schizophreniform symptoms in well-described constellations. In the literature, juvenile myoclonic epilepsy has been linked to emotionally unstable personality traits, depression, anxiety, and executive dysfunction; however, the association with schizophrenia is largely unclear...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29755393/language-lateralization-and-auditory-attention-impairment-in-young-adults-at-ultra-high-risk-for-psychosis-a-dichotic-listening-study
#15
Ingvild Aase, Kristiina Kompus, Jens Gisselgård, Inge Joa, Jan O Johannessen, Kolbjørn Brønnick
Objectives: Impaired attention and language functions are common in psychosis, but have been less explored in subjects with ultra-high risk for psychosis (UHR). The aim of the study was to investigate differences in language lateralization and auditory attention in UHR subjects compared to healthy controls with a dichotic listening paradigm. In addition, symptoms from The Structural Interview for Prodromal Syndromes (SIPS) were explored in relation to performance on dichotic listening. Methods: The UHR subjects ( n = 46, female = 28, mean age = 17...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29733409/neural-correlates-of-auditory-verbal-hallucinations-in-schizophrenia-and-the-therapeutic-response-to-theta-burst-transcranial-magnetic-stimulation
#16
Xingui Chen, Gong-Jun Ji, Chunyan Zhu, Xiaomeng Bai, Lu Wang, Kongliang He, Yaxiang Gao, Longxiang Tao, Fengqiong Yu, Yanghua Tian, Kai Wang
Auditory verbal hallucinations (AVHs) are a core symptom of schizophrenia, and resistant to antipsychotic medication in a substantial proportion of patients. This study aimed to investigate the neural correlates of AVHs in schizophrenia patients and its response to a modified continuous theta-burst stimulation (cTBS) by transcranial magnetic stimulation. In a cross-sectional experiment, resting-state functional magnetic resonance images were collected from 31 AVH schizophrenia patients, 26 non-AVH schizophrenia patients, and 33 sex-/age-matched healthy controls (HCs)...
May 3, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29713292/avatar-therapy-for-persistent-auditory-verbal-hallucinations-in-an-ultra-resistant-schizophrenia-patient-a-case-report
#17
Laura Dellazizzo, Stéphane Potvin, Kingsada Phraxayavong, Pierre Lalonde, Alexandre Dumais
Effective treatment strategies for schizophrenia remain very challenging and many treatment-resistant patients will suffer from persistent auditory verbal hallucinations (AVH). While clozapine is the gold-standard medication for this complex population, many will not respond to this molecule. For these ultra-resistant patients, limited options are available. Cognitive-behavioral therapy (CBT) is the most widely used psychological intervention, though it offers modest effects. With the interpersonal dimension of AVH being recognized, Avatar Therapy (AT), a novel experiential treatment enabling patients to create an avatar of their persecutor and allowing them to gain control over their symptoms, was developed and tested...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29703662/dysregulation-of-auditory-neuroplasticity-in-schizophrenia
#18
Patrice Voss, Maryse E Thomas, Gerson D Guercio, Etienne de Villers-Sidani
Schizophrenia is a complex brain syndrome characterized by an array of positive symptoms (delusions, hallucinations, disorganized speech), negative symptoms (alogia, apathy, avolition) and cognitive impairments (memory, executive functions). Although investigations of the cognitive deficits in schizophrenia have primarily concentrated on disturbances affecting higher-order cognitive processes, there is an increasing realization that schizophrenia also affects early sensory processing, which might, in fact, play a significant role in the development of higher-order cognitive impairments...
April 24, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29684224/mismatch-negativity-and-cortical-thickness-in-patients-with-schizophrenia-and-bipolar-disorder
#19
Sungkean Kim, Hyeonjin Jeon, Kuk-In Jang, Yong-Wook Kim, Chang-Hwan Im, Seung-Hwan Lee
Introduction: Mismatch negativity (MMN) is a measure of automatic neurophysiological brain processes for detecting unexpected sensory stimuli. This study investigated MMN reduction in patients with schizophrenia and bipolar disorder and examined whether cortical thickness is associated with MMN, for exploratory purposes. Methods: Electroencephalograms were recorded in 38 patients with schizophrenia, 37 patients with bipolar disorder, and 32 healthy controls (HCs) performing a passive auditory oddball paradigm...
April 19, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29680513/the-relationship-between-illicit-amphetamine-use-and-psychiatric-symptom-profiles-in-schizophrenia-and-affective-psychoses
#20
Alexandra Voce, Rebecca McKetin, Richard Burns, David Castle, Bianca Calabria
This study examines whether illicit amphetamine use is associated with differences in the prevalence of specific psychiatric symptoms in a community sample of individuals diagnosed with schizophrenia or affective psychotic disorders. Data was drawn from the Australian Survey of High Impact Psychosis. The Diagnostic Interview for Psychosis was used to measure substance use and psychiatric symptoms. Participants had used amphetamine within their lifetime and had an ICD-10 diagnosis of schizophrenia (n = 347) or an affective psychotic disorder (n = 289)...
July 2018: Psychiatry Research
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