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Schizophrenia inpatient

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https://www.readbyqxmd.com/read/28814728/prevalence-of-smoking-in-patients-with-bipolar-disorder-major-depressive-disorder-and-schizophrenia-and-their-relationships-with-quality-of-life
#1
Xiao-Hong Li, Feng-Rong An, Gabor S Ungvari, Chee H Ng, Helen F K Chiu, Ping-Ping Wu, Xin Jin, Yu-Tao Xiang
Few studies have compared the prevalence of smoking between patients with bipolar disorder, major depressive disorder (MDD) and schizophrenia. This study examined the prevalence of smoking and its relationships with demographic and clinical characteristics, and quality of life (QOL) in patients with these psychiatric disorders. A total of 1,102 inpatients were consecutively screened. Psychopathology and QOL were measured with standardized instruments. The prevalence of current smoking in the whole sample was 16...
August 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28809128/real-world-adherence-and-economic-outcomes-associated-with-paliperidone-palmitate-versus-oral-atypical-antipsychotics-in-schizophrenia-patients-with-substance-related-disorders-using-medicaid-benefits
#2
Kruti Joshi, Marie-Hélène Lafeuille, Rhiannon Kamstra, Sean Tiggelaar, Patrick Lefebvre, Edward Kim, Yong Yue, Neeta Tandon
AIM: Compare medication utilization, costs and healthcare resource use in schizophrenia patients with substance-related disorders initiated on once-monthly paliperidone palmitate (PP1M) or an oral atypical antipsychotic (OAA). MATERIALS & METHODS: Data from six Medicaid states (07/2009-03/2015) were used to compare outcomes between PP1M and OAA patients. RESULTS: PP1M patients had higher 12-month antipsychotic adherence and persistence than OAA patients...
August 15, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/28806363/clinical-epidemiology-of-single-versus-multiple-substance-use-disorders-polysubstance-use-disorder
#3
Ish P Bhalla, Elina A Stefanovics, Robert A Rosenheck
OBJECTIVE: While research on substance abuse has largely focused on people who have a single substance use disorder (SUD), many people abuse multiple substances. Studies have yet to examine the distinctive characteristics of patients diagnosed with more than 1 SUD and how those with polysubstance use disorder (PSUD) differ from those with a single SUD. METHODS: National Veterans Health Administration data from fiscal year 2012 were used to compare veterans diagnosed 1 SUD to veterans diagnosed with 2-3, and >3 SUDs on demographic characteristics, psychiatric and medical diagnoses, medical and psychiatric service utilization, and psychotropic medication fills...
September 2017: Medical Care
https://www.readbyqxmd.com/read/28798699/schizophrenia-or-atypical-lupus-erythematosus-with-predominant-psychiatric-manifestations-over-25%C3%A2-years-case-analysis-and-review
#4
Axel Mack, Christiane Pfeiffer, E Marion Schneider, Karl Bechter
We observed a case over 25 years of relapsing-remitting schizophrenic spectrum disorder, varying regarding the main symptomatology between more depressive or more schizoaffective or rather typical schizophrenic syndrome. Diseased phases were repeatedly accompanied by minor skin lesions, which were initially classified as mixed tissue disorder. Psychotic phases were waxing-waning over years. During one later relapse, skin involvement was severe, classified to likely represent an allergic reaction to psychopharmaca; this generalized exanthema remitted rapidly with cortisone treatment and azathioprine...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28791485/effectiveness-and-cost-effectiveness-of-an-integrated-care-program-for-schizophrenia-an-analysis-of-routine-data
#5
Linda Kerkemeyer, Jürgen Wasem, Anja Neumann, Werner Brannath, Benjamin Mester, Jürgen Timm, Thomas Wobrock, Claudia Bartels, Peter Falkai, Janine Biermann
In Germany, a regional social health insurance fund provides an integrated care program for patients with schizophrenia (IVS). Based on routine data of the social health insurance, this evaluation examined the effectiveness and cost-effectiveness of the IVS compared to the standard care (control group, CG). The primary outcome was the reduction of psychiatric inpatient treatment (days in hospital), and secondary outcomes were schizophrenia-related inpatient treatment, readmission rates, and costs. To reduce selection bias, a propensity score matching was performed...
August 8, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28779851/a-tale-of-two-sites-differential-impairment-of-frequency-and-duration-mismatch-negativity-across-a-primarily-inpatient-versus-a-primarily-outpatient-site-in-schizophrenia
#6
Migyung Lee, Pejman Sehatpour, Elisa C Dias, Gail S Silipo, Joshua T Kantrowitz, Antigona M Martinez, Daniel C Javitt
Deficits in mismatch negativity (MMN) generation are among the best replicated neurophysiological deficits in schizophrenia, with reduced amplitude reflecting impaired information processing at the level of supratemporal auditory cortex. Differential patterns of MMN dysfunction according to deviant types have been reported across studies, with some research groups showing impairment in duration MMN but not frequency MMN, and other research groups reporting both findings. We evaluate the hypothesis that recruitment setting, reflecting current functional status, might be an important determinant of the pattern of MMN dysfunction...
August 2, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28774193/declining-clinical-course-of-psychotic-disorders-over-the-two-decades-following-first-hospitalization-evidence-from-the-suffolk-county-mental-health-project
#7
Roman Kotov, Laura Fochtmann, Kaiqiao Li, Marsha Tanenberg-Karant, Eduardo A Constantino, Joan Rubinstein, Greg Perlman, Eva Velthorst, Anne-Kathrin J Fett, Gabrielle Carlson, Evelyn J Bromet
OBJECTIVE: Kraepelin considered declining course a hallmark of schizophrenia, but others have suggested that outcomes usually stabilize or improve after treatment initiation. The authors investigated this question in an epidemiologically defined cohort with psychotic disorders followed for 20 years after first hospitalization. METHOD: The Suffolk County Mental Health Project recruited first-admission patients with psychosis from all inpatient units of Suffolk County, New York (response rate, 72%)...
August 4, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28767928/trends-in-the-prescription-of-clozapine-in-a-psychiatric-hospital-a-5-year-observational-study
#8
Gabriela Danielski Niehues, Alexandre Balestieri Balan, Vinicius Brum Prá, Raphaela Santos Pellizzaro, Paulo Roberto Antunes da Silva, Manuela Danielski Niehues, Ana Paula Costa, Marcelo Liborio Schwarzbold, Alexandre Paim Diaz
Introduction: Clozapine is a well-recognized effective treatment for some patients with treatment-resistant schizophrenia (TRS). Although it has potential benefits and approximately 30% of patients have a clinical indication for clozapine use, prescription rates are low. Objective: To evaluate clozapine prescription trends over a 5-year period in a tertiary psychiatric hospital. Methods: In this observational study, data prospectively collected by the Medical and Statistical File Service (Serviço de Arquivo Médico e Estatístico) and the Pharmacy Division of Instituto de Psiquiatria de Santa Catarina between January 2010 and December 2014 were summarized and analyzed by investigators blinded to data collection...
July 31, 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28761468/seroepidemiological-study-of-toxoplasma-gondii-infection-among-psychiatric-patients-in-mashhad-northeast-of-iran
#9
Ebrahim Abdollahian, Reza Shafiei, Naghmeh Mokhber, Kurosh Kalantar, Abdolmajid Fata
BACKGROUND: Psychiatric patients have an increased risk of some infections like toxoplasmosis. Investigations on Toxoplasma gondii infection among psychiatric patients have been limited in Mashhad, Northeast of Iran. In this case-control study, prevalence of T. gondii was investigated by serological method. METHODS: This case-control study was performed among psychiatric patients admitted to Avicenna Hospital in Mashhad, Northeast of Iran. Three hundred and fifty inpatients and 350 controls were examined in 2012-2013 for detection of IgG and IgM antibodies against T...
January 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28750232/effects-of-chair-yoga-therapy-on-physical-fitness-in-patients-with-psychiatric-disorders-a-12-week-single-blind-randomized-controlled-trial
#10
Saeko Ikai, Hiroyuki Uchida, Yuya Mizuno, Hideaki Tani, Maki Nagaoka, Kenichi Tsunoda, Masaru Mimura, Takefumi Suzuki
INTRODUCTION: Since falls may lead to fractures and have serious, potentially fatal outcomes, prevention of falls is an urgent public health issue. We examined the effects of chair yoga therapy on physical fitness among psychiatric patients in order to reduce the risk of falls, which has not been previously reported in the literature. METHODS: In this 12-week single-blind randomized controlled trial with a 6-week follow-up, inpatients with mixed psychiatric diagnoses were randomly assigned to either chair yoga therapy in addition to ongoing treatment, or treatment-as-usual...
July 19, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28749830/characteristics-of-patients-involved-in-physical-assault-in-an-acute-inpatient-psychiatric-setting
#11
Sohag N Sanghani, Akeem N Marsh, Majnu John, Arya Soman, Leonardo V Lopez, Yolana A Young, Mark J Russ
BACKGROUND: Although aggressive behavior in psychiatric settings is a major concern, very few studies have focused exclusively on physical assault in a general inpatient psychiatric population. OBJECTIVES: This study had 3 main goals: (1) to evaluate the prevalence of assaultive behavior in an acute psychiatric hospital; (2) to identify the clinical and socio-demographic factors associated with assaultive behavior during hospitalization; and (3) to explore whether a diagnosis of schizophrenia spectrum disorder increases the risk of assaultive behavior...
July 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/28741387/baseline-characteristics-and-treatment-patterns-of-patients-with-schizophrenia-initiated-on-once-every-three-month-paliperidone-palmitate-in-the-real-world-setting
#12
Kruti Joshi, Marie-Hélène Lafeuille, Brianne Brown, Willy Wynant, Bruno Emond, Patrick Lefebvre, Neeta Tandon
OBJECTIVES: Since May 2015, adult patients with schizophrenia adequately treated with once-monthly paliperidone palmitate (PP1M) may be transitioned to once-every-three-month paliperidone palmitate (PP3M). This study aims to describe baseline characteristics and treatment patterns of patients with schizophrenia initiated on PP3M in the real-world setting. METHODS: Pharmacy and medical claims from 05/2014-09/2016 for adult patients with schizophrenia initiated on PP3M (index date) in the Symphony Health Solutions database were analyzed...
July 25, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28726159/diagnosis-and-treatment-delays-among-elderly-breast-cancer-patients-with-pre-existing-mental-illness
#13
Kristy Iglay, Melissa L Santorelli, Kim M Hirshfield, Jill M Williams, George G Rhoads, Yong Lin, Kitaw Demissie
PURPOSE: This study aimed to compare diagnosis and treatment delays in elderly breast cancer patients with and without pre-existing mental illness. METHODS: A retrospective cohort study was conducted using the Surveillance, Epidemiology and End Results-Medicare data including 16,636 women 68+ years, who were diagnosed with stage I-IIIa breast cancer in the United States from 2005 to 2007. Mental illness was identified using International Classification of Diseases, Ninth Revision, Clinical Modification codes recorded on inpatient and outpatient claims during the 3 years prior to breast cancer diagnosis...
July 19, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28712353/cost-effectiveness-of-a-ptsd-intervention-tailored-for-individuals-with-severe-mental-illness
#14
Eric P Slade, Jennifer D Gottlieb, Weili Lu, Philip T Yanos, Stanley Rosenberg, Steven M Silverstein, Shula K Minsky, Kim T Mueser
OBJECTIVE: This study examined the cost-effectiveness of a cognitive-behavioral therapy (CBT) intervention for posttraumatic stress disorder (PTSD) that is tailored for adults with a co-occurring severe mental illness. METHODS: Data were from a randomized trial involving 183 adult clients of two outpatient clinics and three partial hospitalization programs. All had a severe mental illness diagnosis (major mood disorder, schizophrenia, or schizoaffective disorder) and severe PTSD...
July 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28709057/predictive-validity-of-the-short-term-assessment-of-risk-and-treatability-start-for-multiple-adverse-outcomes-the-effect-of-diagnosis
#15
Rebecca Marriott, Laura E O'Shea, Marco M Picchioni, Geoffrey L Dickens
The Short-Term Assessment of Risk and Treatability (START) assists risk assessment for seven risk outcomes based on scoring of risk and protective factors and assignment of clinically-informed risk levels. Its predictive validity for violence and self-harm has been established in males with schizophrenia, but accuracy across pathologically diverse samples is unknown. Routine START assessments and 3-month risk outcome data of N = 527 adult, inpatients in a UK secure mental health facility were collected. The sample was divided into diagnostic groups; predictive validity was established using receiver operating characteristics regression (rocreg) analysis in which potential covariates were controlled...
July 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28700014/predictors-of-length-of-stay-in-an-acute-psychiatric-inpatient-facility-in-a-general-hospital-a-prospective-study
#16
Fernanda L Baeza, Neusa S da Rocha, Marcelo P Fleck
Objective: There have been significant reductions in numbers of psychiatric beds and length of stay (LOS) worldwide, making LOS in psychiatric beds an interesting outcome. The objective of this study was to find factors measurable on admission that would predict LOS in the acute psychiatric setting. Methods: This was a prospective, observational study. Results: Overall, 385 subjects were included. The median LOS was 25 days. In the final model, six variables explained 14...
July 6, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28688338/pregnenolone-as-an-adjunct-to-risperidone-for-treatment-of-women-with-schizophrenia-a-randomized-double-blind-placebo-controlled-clinical-trial
#17
Ladan Kashani, Nazila Shams, Ehsan Moazen-Zadeh, Mohammad-Ali Karkhaneh-Yousefi, Gita Sadighi, Mohammad-Reza Khodaie-Ardakani, Farzin Rezaei, Fatemeh Rahiminejad, Shahin Akhondzadeh
There have been few studies of pregnenolone therapy in schizophrenia and those that exist have been subject to several critical limitations, thus yielding inconsistent results. We attempted to assess the therapeutic effect of pregnenolone in a patient sample as homogeneous as possible. In this randomized double-blind clinical trial, 82 female inpatients with chronic schizophrenia, who had discontinued their antipsychotic medications for at least one week in case of any oral antipsychotic medication or a month for any depot antipsychotic medication, received risperidone plus either pregnenolone (50 mg/day) or placebo for 8 weeks...
June 28, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28674870/heart-rate-response-to-alpha2-adrenergic-receptor-antagonism-by-antipsychotics
#18
David D Kim, Donna J Lang, Darren E R Warburton, Melissa L Woodward, Randall F White, Alasdair M Barr, William G Honer, Ric M Procyshyn
PURPOSE: To explore the relationship between antipsychotic-associated antagonism of alpha2-adrenergic receptors and resting heart rate in individuals with schizophrenia. METHODS: Thirty-one inpatients treated with antipsychotics were included in this exploratory analysis. Antipsychotic doses were converted to haloperidol equivalents for alpha2-adrenergic receptor antagonism. Resting heart rate was measured with the patient in the seated upright posture. RESULTS: After controlling for confounding variables, the relationship between alpha2-adrenergic receptor antagonism and resting heart rate demonstrated a positive linear effect (P = 0...
July 3, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28669289/outpatient-follow-up-care-and-risk-of-hospital-readmission-in-schizophrenia-and-bipolar-disorder
#19
Steven C Marcus, Chien-Chia Chuang, Daisy S Ng-Mak, Mark Olfson
OBJECTIVE: Although outpatient care within 30 days of mental health hospital discharge is an established quality indicator, little is known about the clinical implications of not receiving such care. This study evaluated whether receipt of outpatient care within 30 days of discharge was associated with a reduced risk of readmission during days 31-120 postdischarge among adult inpatients with schizophrenia or bipolar disorder. METHODS: Retrospective longitudinal cohort analyses were performed with Truven MarketScan Commercial (2010-2014) and Medicaid (2010-2013) databases...
July 3, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28658994/socioeconomic-disadvantage-and-schizophrenia-in-migrants-under-mental-health-detention-orders
#20
Jan Bulla, Klaus Hoffmann, Jan Querengässer, Thomas Ross
BACKGROUND: Migrants with mental hospital orders according to section 63 of the German criminal code are overrepresented in relation to their numbers in the general population. Subgroups originating from certain world regions are diagnosed with schizophrenia at a much higher rate than others. In the present literature, there is a strong evidence for a substantial correlation between migration, social disadvantage and the prevalence of schizophrenia. AIMS: This study investigates the relationship between countries of origin, the risk of becoming a forensic patient and the proportion of schizophrenia spectrum disorders...
June 1, 2017: International Journal of Social Psychiatry
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