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Toxocariasis

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https://www.readbyqxmd.com/read/28302681/ultrasound-biomicroscopic-imaging-in-paediatric-ocular-toxocariasis
#1
Jinghua Liu, Songfeng Li, Guangda Deng, Wenli Yang, Wei Chen, Hai Lu
PURPOSE: To determine the potential and usefulness of ultrasound biomicroscopy (UBM) as a diagnostic procedure on a larger cohort of paediatric patients with ocular toxocariasis. METHODS: UBM was performed on 41 eyes of 41 patients with ocular toxocariasis in order to determine configuration of peripheral retina, pars plana and vitreous. Location and range of peripheral pathology using ophthalmoscopy with scleral indentation, UBM and intraoperative confirmation were recorded and compared...
March 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28259548/seroprevalence-of-five-neglected-parasitic-diseases-among-immigrants-accessing-five-infectious-and-tropical-diseases-units-in-italy-a-cross-sectional-study
#2
Giulia Martelli, Chiara Di Girolamo, Lorenzo Zammarchi, Andrea Angheben, Matteo Morandi, Stefano Tais, Monica Degani, Issa El Hamad, Silvio Caligaris, Anna Ciannameo, Elisabetta Grilli, Lucia Urbinati, Geraldo Badona Monteiro, Carmelo Scarcella, Nicola Petrosillo, Margherita Digaetano, Lorenzo Rabbi, Noemi Bazzanini, Francesca Cacciatore, Brigida Lilia Marta, Maria Luisa Moro, Alessandro Bartoloni, Pierluigi Viale, Gabriella Verucchi
OBJECTIVE: This multicentre cross-sectional study aims to estimate the prevalence of five neglected tropical diseases (Chagas disease, filariasis, schistosomiasis, strongyloidiasis, toxocariasis) among immigrants accessing health care facilities in five Italian cities (Bologna, Brescia, Florence, Rome, Verona). METHODS: Individuals underwent a different set of serological tests, according to country of origin and presence of eosinophilia. Seropositive patients were treated and further followed up...
March 1, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28188768/frequency-of-toxocara-spp-antibodies-in-umbilical-cords-of-newborns-attended-atthe-university-hospital-in-southern-brazil-and-factors-associated-with-infection
#3
Paula Costa Santos, Paula Lima Telmo, Lis Maurente Lehmann, Carolina Lorenzi, Carolina Hirsch, Gabriela Torres Mattos, Gabriel Baracy Klafke, Maria Elisabeth Aires Berne, Carla Vitola Gonçalves, Carlos James Scaini
Toxocariasis is a neglected and geographically widespread parasitic disease. The detection of specific antibodies associated with this disease is required to confirm its clinical diagnosis and to aid in prevention. Although helminth infection during pregnancy can promote foetal immune responses with long-term effects, specific information regarding the risk of Toxocara spp. infection to the human foetus during pregnancy is lacking. Therefore, the present study aimed to investigate the frequency of antibodies against Toxocara spp...
February 8, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28164001/abdominal-mass-secondary-to-human-toxocariasis
#4
Javad Ghoroobi, Leily Mohajerzadeh, Maliheh Khoddami, Alireza Mirshemirani, Naser Sadeghian, Alireza Mahdavi, Sayeh Hatefi
Toxocariasis is an extensive helminthic infection that leads to visceral larva migrans in humans. A 2.5-year-old girl referred for abdominal mass. She had history of pharyngitis for two weeks. There were no other symptoms. Abdominal examination revealed an irregular solid mass in right lower quadrant (RLQ). Abdominal ultrasonography revealed an echohetrogenic large mass in RLQ, liver, and retroperitoneal area. Abdominal CT scan showed a huge mass. At laparotomy a large retroperitoneal mass that involved right liver lobe, bladder, ileocecal valve, small and large intestines was found...
January 2017: APSP Journal of Case Reports
https://www.readbyqxmd.com/read/28157623/toxocariasis-of-the-central-nervous-system-with-report-of-two-cases
#5
Bouthouri Abir, Mansour Malek, Mrissa Ridha
Toxocariasis is a parasitic infection caused by the roundworms Toxocara canis or Toxocara cati, mostly due to accidental ingestion of embryonated eggs. Clinical manifestations vary and are classified according to the organs affected. Central nervous system involvement is an unusual complication. Here, we report two cases with neurological manifestations, in which there was cerebrospinal fluid (CSF) eosinophilia with marked blood eosinophilia and a positive serology for Toxocara both in serum and CSF. Improvement of signs and symptoms after specific treatment was observed in the two cases...
March 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28155105/toxocara-vitulorum-infection-in-german-beef-cattle
#6
Peter L Venjakob, Gerhard Thiele, Peter-Henning Clausen, Ard M Nijhof
Toxocara vitulorum is an ascarid that is frequently found in sub-tropical regions but little is known about infections in more temperate climates. In this study, we report the occurrence of this parasite in a beef cattle herd in eastern Germany. In June 2016, large (14-20 cm) cream-colored worms identified as adult T. vitulorum were observed in the feces of 2- to 3-month-old calves. Eggs of this parasite were subsequently detected in pooled fecal samples collected on all three farm sites. The morphological identification was supported by analysis of partial cytochrome c oxidase I and internal transcribed spacer 1 gene sequences...
February 2, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28151857/association-between-intermediate-uveitis-and-toxocariasis-in-the-korean-population
#7
Jin-Woo Kwon, Yoonseob Sim, Donghyun Jee
The aim of the study was to investigate the characteristics of ocular toxocariasis (OT) presenting with intermediate uveitis in the Korean population.We studied intermediate uveitis patients using ocular and systemic evaluations and a Toxocara IgG serology test.Of 50 intermediate uveitis patients, 19 were seropositive for Toxocara IgG. Of the 19 OT patients, 4 presented with recurrence within 6 months and were significantly younger than nonrecurrence patients (P = 0.009). Thirteen patients had a history of eating raw cow liver...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28141958/genetic-analysis-of-toxocara-cati-nematoda-ascarididae-from-guangdong-province-subtropical-china
#8
Xi He, Meng-Na Lv, Guo-Hua Liu, Rui-Qing Lin
Toxocara cati (cat roundworm) is a common parasitic nematode that infects humans and other hosts, causing toxocariasis. Although its significance as a pathogen, the epidemiology, genetics and biology of T. cati remain poorly understand in China. In the present study, genetic variation in mitochondrial (mt) cytochrome c oxidase subunit 1 (cox1) gene and internal transcribed spacer (ITS) of rDNA region among T. cati in Guangdong province, subtropical China was examined. A portion of the cox1 (pcox1) and the complete ITS (ITS1 + 5...
January 31, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/28138052/estimating-burdens-of-neglected-tropical-zoonotic-diseases-on-islands-with-introduced-mammals
#9
Luz A de Wit, Donald A Croll, Bernie Tershy, Kelly M Newton, Dena Spatz, Nick D Holmes, A Marm Kilpatrick
Many neglected tropical zoonotic diseases are maintained by introduced mammals, and on islands the most common introduced species are rodents, cats, and dogs. Management of introduced mammals, including control or eradication of feral populations, which is frequently done for ecological restoration, could also reduce or eliminate the diseases these animals carry. Understanding the burden of these zoonotic diseases is crucial for quantifying the potential public health benefits of introduced mammal management...
January 30, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28096863/seroepidemiological-study-of-toxocariasis-in-the-owners-of-domestic-cats-and-dogs-in-mashhad-northeastern-iran
#10
Fariba Berenji, Ali Pouryousef, Abdolmajid Fata, Mahmoud Mahmoudi, Maryam Salehi, Javad Khoshnegah
BACKGROUND: Toxocariasis is the clinical terms applied to infection of human with Ascarid nematodes in the order Ascaridida, named Toxocara canis and T. cati. Because in recent years in Iran many people desire to keep pets (cats and dogs), and lacking of seroepidemiological study of toxocariasis in Mashhad, we decided to determine the seroprevalence of toxocariasis among people who own cats and dogs in comparison with control group. METHODS: A serological study for detection antibodies to Toxocara in two groups (93 cat and dog owners and 93 healthy people as control group) was conducted from Feb 2013 to Dec 2013...
April 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28096624/genetic-variability-and-discrimination-of-low-doses-of-toxocara-spp-from-public-areas-soil-inferred-by-loop-mediated-isothermal-amplification-assay-as-a-field-friendly-molecular-tool
#11
Maryam Ozlati, Adel Spotin, Abbas Shahbazi, Mahmoud Mahami-Oskouei, Teimour Hazratian, Mohammad Adibpor, Ehsan Ahmadpour, Afsaneh Dolatkhah, Paria Khoshakhlagh
ABSTRACT: Aim: One of the main diagnostic problems of conventional polymerase chain reaction (PCR) is indiscrimination of low parasitic loads in soil samples. The aim of this study is to determine the genetic diversity and identification of Toxocara spp. from public areas soil inferred by loop-mediated isothermal amplification (LAMP) assay. MATERIALS AND METHODS: A total of 180 soil samples were collected from various streets and public parks of northwest Iran. The DNA of recovered Toxocara eggs were extracted and amplified by PCR and LAMP following ZnSO4 flotation technique...
December 2016: Veterinary World
https://www.readbyqxmd.com/read/28077610/seroprevalence-of-toxocariasis-in-children-with-urticaria-a-population-based-study
#12
Paula Mayara Matos Fialho, Carlos Roberto Silveira Correa, Susana Zevallos Lescano
OBJECTIVE: This study described the prevalence of IgG class antibodies against Toxocara spp. and their association with urticaria in 2- to 12-year-old children. METHODS: This population-based cross-sectional study was conducted between May 2012 and September 2014. The study sample comprised 168 children. Blood samples were collected to verify the presence of toxocariasis by using ELISA to detect IgG antibodies. The guardians of the children were interviewed to characterize the presence or absence of other diseases, such as urticaria...
January 10, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28043392/influence-of-land-use-and-meteorological-factors-on-the-spatial-distribution-of-toxocara-canis-and-toxocara-cati-eggs-in-soil-in-urban-areas
#13
Xiang Gao, Hongbin Wang, Jianxin Li, Hongyu Qin, Jianhua Xiao
Soil which has been contaminated by Toxocara spp. eggs is considered as one of the main infection sources of Toxocariasis in animals and humans. The present study conducted a detailed investigation into the spatial patterns of Toxocara canis (T. canis) and Toxocara cati (T. cati) eggs in soil in urban area of northeastern Mainland China, and assessed the inter-relationships between meteorological factors, land use and the distribution of the Toxocara spp. eggs. Polymerase chain reaction (PCR) was used for the determination of T...
January 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/27901644/clinical-profile-treatment-and-visual-outcome-of-ocular-toxocara-in-a-tertiary-eye-care-centre
#14
Ekta S Sahu, Bikramjit Pal, Tarun Sharma, Jyotirmay Biswas
PURPOSE: To determine the clinical features, treatment, and visual outcome in ocular toxocariasis. METHODS: A total of 16 cases diagnosed as ocular toxocariasis clinically and/or serologically were analyzed retrospectively. RESULTS: The mean age of the patients was 22.6 years. Cases were categorized into three clinical types with peripheral granuloma (43.7%) as the most common presentation. Of the patients, 10 (62.5%) had positive serum ELISA for T...
November 30, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27866477/cross-reactivity-of-the-31-kda-antigen-of-angiostrongylus-cantonensis-dealing-with-the-immunodiagnosis-of-meningoencephalitis
#15
Alessandra L Morassutti, Lisa N Rascoe, Sukwan Handali, Alexandre J DA Silva, Patricia P Wilkins, Carlos Graeff-Teixeira
The primary causative agent of eosinophilic meningoencephalitis (EoM) in endemic regions is the nematode Angiostrongylus cantonensis. The occurrence of EoM was previously restricted to countries in Southeast Asia and the Pacific Islands; however, more recently, it has been reported from other regions, including Brazil. The commonly used diagnosis is detection of specific antibody reactivity to the 31 kDa antigen, which is derived from female worm somatic extracts. Here we report the occurrence of cross-reactivity to this antigen in sera from other parasitic infections, especially those that may cause EoM, such as gnathostomiasis, toxocariasis, hydatidosis and strongyloidiasis...
November 21, 2016: Parasitology
https://www.readbyqxmd.com/read/27857820/detection-of-specific-antibody-reactivity-to-toxocara-larval-excretory-secretory-antigens-in-asthmatic-patients-5-15-years
#16
Mahdi Mosayebi, Latif Moini, Reza Hajihossein, Mojtaba Didehdar, Zahra Eslamirad
BACKGROUND & PURPOSE: Humans act as an intermediate host for Toxocara canis and Toxocara cati. Toxocara may be an important risk factor for asthma in humans. The aim of the present study was to evaluate immunoglobulin G (IgG) anti-Toxocara canis antibody, using enzyme-linked immunosorbent assay (ELISA) in asthmatic patients (aged 5-15 years), referring to a clinic of pulmonary diseases in Arak, Iran. MATERIALS & METHODS: In this bi-group cross sectional study, serum samples were collected from 110 children with confirmed asthma and 70 children without asthma within one year...
2016: Open Microbiology Journal
https://www.readbyqxmd.com/read/27845205/comparative-transcriptomic-analyses-of-male-and-female-adult-toxocara-canis
#17
COMPARATIVE STUDY
Rong-Qiong Zhou, Guang-Xu Ma, Pasi K Korhonen, Yong-Li Luo, Hong-Hong Zhu, Yong-Fang Luo, Robin B Gasser, Qing-You Xia
Toxocariasis is an important, neglected zoonosis caused mainly by Toxocara canis. Although our knowledge of helminth molecular biology is improving through completed draft genome projects, there is limited detailed information on the molecular biology of Toxocara species. Here, transcriptomic sequencing of male and female adult T. canis and comparative analyses were conducted. For each sex, two-thirds (66-67%) of quality-filtered reads mapped to the gene set of T. canis, and at least five reads mapped to each of 16,196 (87...
February 5, 2017: Gene
https://www.readbyqxmd.com/read/27812663/toxocara-spp-seroprevalence-in-pregnant-women-in-bras%C3%A3-lia-brazil
#18
Lívia Custódio Pereira, Guita Rubinsky Elefant, Yanna Medeiros Nóbrega, Tamires Vital, Nadjar Nitz, Lenora Gandolfi, Riccardo Pratesi, Mariana Hecht
INTRODUCTION: The impact of gestational toxocariasis is an understudied topic on female reproductive health. We estimated anti-Toxocara IgG prevalence among pregnant women in Brasília, Brazil, and investigated the association of the infection with history of abortion and contact with pets. METHODS: Infection was diagnosed using ELISA with excretory/secretory antigens. Participant information was obtained via questionnaires. RESULTS: Of 311 pregnant women, 23 were anti-Toxocara IgG positive...
September 2016: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/27809350/clinical-usefulness-of-western-blotting-and-elisa-avidity-for-the-diagnosis-of-human-toxocariasis
#19
Monika Rudzińska, Beata Kowalewska, Katarzyna Sikorska
The serodiagnosis of human toxocariasis is difficult. Specific IgGs detected routinely with ELISA based on Toxocara excretory-secretory (TES) antigens often persist for years at an elevated level, which does not allow either the differentiation between an active and persistent infection or monitoring the effect of treatment. Additionally, false positive results may occur in co-infections with other helminths due to cross-reactions. We evaluated the usefulness of an IgG avidity index (AI) and a Western blotting (WB) IgG in the diagnosis of patients suspected of Toxocara infection...
November 3, 2016: Parasite Immunology
https://www.readbyqxmd.com/read/27800525/staphylococcus-aureus-endocarditis-as-a-complication-of-toxocariasis-associated-endomyocarditis-with-fibrosis-a-case-report
#20
Esther Kuenzli, Niklaus Labhardt, Gianmarco Balestra, Maja Weisser, Michael J Zellweger, Johannes Blum
Complications associated with Toxocara canis infection are rare. We present a case of a patient with Staphylococcus aureus endocarditis as a complication of an endomyocardial fibrosis caused by T canis. The epidemiological, pathological, and clinical features of this rare complication are described here.
September 2016: Open Forum Infectious Diseases
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