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Khurul Ain Mohamed Mahzir, Siti Salwa Abd Gani, Uswatun Hasanah Zaidan, Mohd Izuan Effendi Halmi
In this study, the optimal conditions for the extraction of antioxidants from the Buah Mahkota Dewa fruit ( Phaleria macrocarpa) was determined by using Response Surface Methodology (RSM). The optimisation was applied using a Central Composite Design (CCD) to investigate the effect of three independent variables, namely extraction temperature (°C), extraction time (minutes) and extraction solvent to-feed ratio (% v / v ) on four responses: free radical scavenging activity (DPPH), ferric ion reducing power assay (FRAP), total phenolic content (TPC) and total flavonoid content (TFC)...
March 22, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Ashraf M Abdel-Moneim, Mohamed A Al-Kahtani, Omar M Elmenshawy, Hany Elsawy, Aly M Hafez, Marwa A Genena
In this field study, the levels of heavy metals (Pb, Fe, Co, Cu, and Zn) in water and a suite of biochemical and histological biomarkers in the grouper ( Epinephelus tauvina) were assessed at four sites in the Arabian Gulf. Samples were taken from a relatively non-urban reference site, called Salwa (S1), and three effluent-dominated sites, namely Al-aziziyah in southern Dammam city (S2), the Al-Jubail coast (S3), and Manifa (S4). Toxic metals, namely Pb and Co (at all sites) and Fe (at S3), were elevated in water samples relative to the internationally permissible limits...
January 1, 2018: Toxicology and Industrial Health
Khaled Abu Saman, Salwa Massad, Ali Abu Ibaid, Huda Anan, Mamhoud Daher, Rand Salman, Saleh Aldeqes
BACKGROUND: About 9% of the world's population has diabetes. Most people with diabetes live in developing countries. Diabetes is the fourth leading cause of death in the occupied Palestinian territory. The likelihood of diabetes complications increases with depression. Worldwide, about half of patients with diabetes have severe depression that has been misidentified by health providers. The aim of this study was to examine factors associated with depression in patients with type 2 diabetes in the Gaza governorate...
February 21, 2018: Lancet
Marika Houde, Nastaran Khodaei, Noreddine Benkerroum, Salwa Karboune
Protein concentrates were prepared from defatted barley (Hordeum vulgare L.) flour using alkaline and enzymatic treatments. Milder enzymatic treatments included (i) a bi-enzymatic method involving the use of starch-hydrolyzing enzymes, and (ii) a tri-enzymatic method using the former bi-enzymatic treatment followed by digestion with glucanase. The concentrate obtained through alkaline extraction (AI-BP) was comprised mainly of low molecular weight fractions of proteins. Bi-enzymatic treatment produced a protein concentrate with the highest protein content (49...
July 15, 2018: Food Chemistry
Houda Bouhajja, Rania Abdelhedi, Ali Amouri, Faten Hadj Kacem, Rim Marrakchi, Wajdi Safi, Houcem Mrabet, Lassaad Chtourou, Nadia Charfi, Mouna Fourati, Salwa Bensassi, Kamel Jamoussi, Mohamed Abid, Hammadi Ayadi, Mouna Mnif Feki, Noura Bougacha Elleuch
BACKGROUND: The relationship between liver enzymes and type 2 diabetes (T2D) risk is inconclusive. We aimed to evaluate the association between liver markers and risk of carbohydrate metabolism disorders and their discriminatory power for T2D prediction. METHODS: This cross-sectional study enrolled 216 participants classified as normoglycemic, prediabetes, newly-diagnosed diabetes and diagnosed diabetes. All participants underwent anthropometric and biochemical measurements...
March 10, 2018: Canadian Journal of Physiology and Pharmacology
Rita Rahmeh, Abrar Akbar, Mohamed Kishk, Thanyan Al Onaizi, Aisha Al-Shatti, Anisha Shajan, Batool Akbar, Salwa Al-Mutairi, Awatef Yateem
Food safety has become an issue of great interest worldwide. Listeria monocytogenes is a food-borne pathogen that causes listeriosis and is difficult to control in the dairy industry. The use of lactic acid bacteria (LAB) and their antimicrobial substances against Listeria is promising in food applications. Here, we report the isolation from raw camel milk of LAB displaying antilisterial activity. Two isolates were selected for their secretion of bacteriocin(s) and identified by 16S rRNA sequencing as Enterococcus faecium S6 and R9...
March 7, 2018: Journal of Dairy Science
Abir Salwa Ali, Malin Grönberg, Seppo W Langer, Morten Ladekarl, Geir Olav Hjortland, Lene Weber Vestermark, Pia Österlund, Staffan Welin, Henning Grønbæk, Ulrich Knigge, Halfdan Sorbye, Eva Tiensuu Janson
High-grade gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs, G3) are aggressive cancers of the digestive system with poor prognosis and survival. Platinum-based chemotherapy (cisplatin/carboplatin + etoposide) is considered the first-line palliative treatment. Etoposide is frequently administered intravenously; however, oral etoposide may be used as an alternative. Concerns for oral etoposide include decreased bioavailability, inter- and intra-patient variability and patient compliance. We aimed to evaluate possible differences in progression-free survival (PFS) and overall survival (OS) in patients treated with oral etoposide compared to etoposide given as infusion...
March 6, 2018: Medical Oncology
Salwa A Mohammad, Basma K Ramadan, Mona F Schaalan
No abstract text is available yet for this article.
March 2018: Canadian Journal of Physiology and Pharmacology
Tassos Irinakis, Salwa Aldahlawi
Achieving symmetry of the soft-tissue margins between anterior maxillary dental-implant restorations and adjacent teeth is a therapeutic challenge for both the implant surgeon and the restorative dentist. This article describes a modified procedure utilizing autogenous connective-tissue grafts to improve primarily buccal soft-tissue margins and secondarily inter-proximal tissues around tooth-bound single dental implants. This technique has the advantage of allowing for coronal augmentation of the peri-implant soft tissue while maximizing the blood supply to the area by using tunneling-technique principles...
2018: Clinical, Cosmetic and Investigational Dentistry
Michelle Long, Ken J Farion, Roger Zemek, Debby Voskamp, Nick Barrowman, Salwa Akiki, Sarah Reid
Background: Hyperbilirubinemia is a common neonatal condition requiring timely management to prevent acute bilirubin encephalopathy. Management protocols allow nonphysicians to initiate designated actions prior to physician assessment. Objective: To assess the effectiveness of a nurse-initiated neonatal jaundice management protocol for serum bilirubin sampling and phototherapy for neonates presenting with hyperbilirubinemia to the Paediatric Emergency Department (PED)...
August 2017: Paediatrics & Child Health
Omar Laraqui, Nadia Manar, Salwa Laraqui, Mehdi Boukili, Tarik Ghailan, Frédéric Deschamps, Chakib El Houssine Laraqui
OBJECTIVES: The aim of this study was to evaluate the well-being and occupational perception of healthcare workers in Morocco. METHODS: This observational and cross-sectional survey, carried out by self-administered questionnaire, was conducted in public hospitals in three cities. The target population consisted of 2,453 healthcare workers, comprising physicians and paramedics with at least two years of clinical experience. RESULTS: 1951 healthcare workers returned the questionnaire (29...
November 2017: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
Salwa A Alsadhan, Najla F Alsayari, Mashael F Abuabat
OBJECTIVES: The main aim of this cross-sectional study was to assess knowledge concerning traumatic dental injuries and their management among primary schoolteachers in Riyadh, Saudi Arabia. The secondary objective was to evaluate the effect of gender, nationality, marital status, school type, geographical area, age group, level of education and years of experience on teachers' knowledge. METHODOLOGY: Data were collected, through a self-administered questionnaire, from both male and female teachers employed in public and private primary schools in the five geographical areas of Riyadh City...
February 22, 2018: International Dental Journal
A Maurya, H N Shivakumar, S Honnavar, M Salwa, S N Murthy
The prevalence of Iron Deficiency Anemia (IDA) is predominant in women and children especially in developing countries. The disorder affects cognitive functions and physical activity. While oral iron supplementation and parenteral therapy remains the preferred choice of treatment, gastric side effects and risk of iron overload decreases adherence to therapy. Transdermal route is an established approach which circumvents the side-effects associated with conventional therapy. In this project, an attempt was made to investigate the use of rapidly dissolving microneedles loaded with Ferric pyrophosphate (FPP) as a potential therapeutic approach for management of IDA...
February 17, 2018: Journal of Pharmaceutical Sciences
Salwa Al-Mouqatea, Mohammad Alkhamis, Batool Akbar, Abdulmohsen Ali, Hameed Al-Aqeel, Ahmed Bin-Heji, Mohammed Razzaque, Julio Alvarez, Andres Perez
Bovine tuberculosis (TB) is endemic in Kuwait; cattle identified as TB-positive using the caudal fold test (CFT) are culled. We used a Bayesian approach to estimate the sensitivity (Se) and specificity (Sp) of the IFNγ assay and ELISA, which are not routinely used in Kuwait in CFT-negative dairy cattle. Blood samples from CFT-negative cattle ( n = 384) collected from 38 dairy farms were tested by IFNγ assay and ELISA. The Se and Sp (95% CI) of the IFNγ were 85.0% (67.6-95.3%) and 90.4% (86.7-95.3%), respectively, whereas estimates for the ELISA were 61...
February 1, 2018: Journal of Veterinary Diagnostic Investigation
Mohammad Nabil Abo-Zeid, Noha N Atia, Samia M El-Gizawy, Salwa R El-Shaboury
Direct-acting antivirals (DAAs) represent a revolution in the treatment of chronic hepatitis C which have emerged at an extremely rapid pace over the past few years. DAAs act directly on the hepatitis C virus at various points in the viral life cycle to inhibit viral production. Among these novel DAAs, are daclatasvir (DCS) and ledipasvir (LDS). Herein, a novel, fast, simple, ultrasensitive and cost-effective spectrofluorimetric method was designed for determination of DCS and LDS in miscellaneous matrices...
January 31, 2018: Journal of Pharmaceutical and Biomedical Analysis
Ahmed Ibrahim El-Batal, Salwa Farid Ahmed
Radiation combined injury, a life-threatening condition, has higher mortality than simple radiation injury. The aim of the present study was to analyze the efficiency of Aloe vera and silver nanoparticles in improving the healing of ulcerated oral mucosa after irradiation. Thirty male Albino mice were divided into five groups: control, radiation, Aloe vera (AV), silver nanoparticles (NS), and AV+NS. The mice were exposed to whole body 6Gy gamma-radiation. After one hour, 20% acetic acid was injected into the submucosal layer of the lower lip for ulcer induction...
February 5, 2018: Brazilian Oral Research
Wafaa Ahmed, Dina Mofed, Abdel-Rahman Zekri, Nasr El-Sayed, Mohamed Rahouma, Salwa Sabet
Objective To evaluate the antioxidant and apoptotic inductive effects of Withania somnifera (Ashwagandha) leaf extract against a hepatocellular carcinoma cell line. Methods After treating HepG2cells with Ashwagandha water extract (ASH-WX; 6.25 mg/ml-100 mg/ml), cell proliferation was assessed using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Antioxidant activities (total antioxidant, glutathione S-transferase and glutathione reductase), Fas-ligand level, tumour necrosis factor-α (TNF-α) level and caspase-3, -8, and -9 activities were measured...
January 1, 2018: Journal of International Medical Research
Salwa S Saadeh, Mark R Litzow
Allogeneic hematopoietic stem cell transplant (allo-HSCT) has an important role in management of acute lymphoblastic leukemia (ALL). Proper patient selection is central to ensure optimal outcomes. Areas covered: This review covers various aspects of HSCT in ALL patients, including indications, donor selection, conditioning regimens, and post-transplant management. Expert commentary: Allo-HSCT is important in post-remission management of ALL but proper risk-stratification is a major challenge. Incorporation of minimal residual disease (MRD) and molecular testing will improve patient allocation...
March 2018: Expert Review of Hematology
Yazeed Alghonaim, Salwa ALRashed ALHumaid, Abdullah Arafat
BACKGROUND: Ossifying fibroma is a rare benign fibro-osseous lesion seen in the bones of the head and neck area. It is mostly found in the mandible followed by the maxilla and rarely in the paranasal sinuses along with the orbit and skull bones. CASE PRESENTATION: A 30-year-old male patient presented with headache and incidental finding of a right ethmoidal sinus ossifying fibroma by paranasal-sinuses CT scan and MRI of the face. A flexible fiber-optic nasal endoscopy examination revealed a right side fullness...
December 26, 2017: International Journal of Surgery Case Reports
Abdullah Alharbi, Salwa Bakr Hassan, Abdul-Kareem Al-Momen, Khalid Al-Saleh, Rasheed Nasr, Haitham Kohgear, Tarek Owaidah
: Von Willebrand disease is a common bleeding disorder. The wide variation in von Willebrand factor (VWF) levels between and within normal individuals highlights the clinical challenge of defining its cutoff value. Although studies on the influence of ethnicity on ABO phenotypes and the levels of VWF have been carried out on different ethnicities, there is a lack of such data among Arab population. We aimed to evaluate the correlation of ABO phenotypes with all the parameters of the minimal test panel of VWF including VWF antigen, VWF activity using the ristocetin cofactor and the collagen binding activity assays, and factor VIII coagulant activity (VWF:Ag, VWF:RCo, VWF:CB and FVIII:C) tested in a normal Arab population, and to estimate ABO-specific normal reference range...
March 2018: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
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