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https://www.readbyqxmd.com/read/28330941/nurse-driven-clinical-pathway-for-inpatient-asthma-a-randomized-controlled-trial
#1
Catherine M Pound, Victoria Gelt, Salwa Akiki, Kaylee Eady, Katherine Moreau, Franco Momoli, Barbara Murchison, Roger Zemek, Brett Mulholland, Tom Kovesi
OBJECTIVE: We examined the impact of a nurse-driven clinical pathway on length of stay (LOS) for children hospitalized with asthma. METHODS: We conducted a randomized controlled trial involving children hospitalized with asthma. Nurses of children in the intervention group weaned salbutamol frequency using an asthma scoring tool, whereas physicians weaned salbutamol frequency for the control group patients as per standard care. The primary outcome was LOS in hours...
March 22, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/28316424/ovicidal-effect-of-chitinase-and-protease-enzymes-produced-by-soil-fungi-on-the-camel-tick-hyalomma-dromedarii-eggs-acari-ixodidae
#2
Salwa M Habeeb, Heba M Ashry, Moataza M Saad
The aim of this study was to evaluate the effect of chitinase and protease enzymes produced by environmentally safe soil Fungi; Aspergillus sp. NRC 4/5H; Mucor sp. NRC 5; Trichoderma sp. NRC 4/56; Aspergillus sojae; Mucor ranosisinus; Aspergillus oryzae on embryo development of the camel tick Hyalomma dromedarii eggs. The experiment was carried out on the 7 day aged eggs. Concentrations of the chitinase and protease crude enzymes [1:1, 1:2, 1:3, 1:4 and 1:5 (v/v)] were prepared from six stock solutions whose concentrations were 5 units/ml each...
March 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28296538/hemolytic-uremic-syndrome-findings-of-post-acute-renal-failure-in-light-and-electron-microscopy
#3
Wiesława Salwa-Żurawska, Jakub Żurawski, Aldona Woźniak, Elżbieta Bortkiewicz, Paweł Burchardt, Przemysław Kwiatkowski, Monika Seget, Piotr Tabaczewski
The blood count test results of six patients (five male adolescents and one female adult) who were diagnosed with the hemolytic-uremic syndrome are presented. Certain diverse lesions and especially, their different intensity, were observed. They were referred to the clinical process and the time from syndrome occurrence to biopsy.
March 15, 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28255550/indolent-lung-opacity-ten-years-follow-up-of-pulmonary-inflammatory-pseudo-tumor
#4
Jad A Degheili, Nadim A Kanj, Salwa A Koubaissi, Mouhamad J Nasser
Inflammatory pseudotumor (IPT) has always been considered a diagnostic challenge. Its rarity and resemblance to other more common pathological entities imposes that neither clinical nor radiological characteristics can lead to a definitive diagnosis. The surgical excision of the lesion is the ultimate approach for accurate diagnosis and cure. Moreover the true nature of IPT, its origin as a neoplastic entity or an over-reactive inflammatory reaction to an unknown trigger, has been a long debated matter. Surgery remains the treatment of choice...
February 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28250648/the-influence-of-pluronic-f68-and-f127-nanocarrier-on-physicochemical-properties-in-vitro-release-and-antiproliferative-activity-of-thymoquinone-drug
#5
Salwa Shaarani, Shahrul Sahul Hamid, Noor Haida Mohd Kaus
BACKGROUND: This study reports on hydrophobic drug thymoquinone (TQ), an active compound found in the volatile oil of Nigella sativa that exhibits anticancer activities. Nanoformulation of this drug could potentially increase its bioavailability to specific target cells. OBJECTIVE: The aim of this study was to formulate TQ into polymer micelle, Pluronic F127 (5.0 wt %) and Pluronic F68 (0.1 wt %), as a drug carrier to enhance its solubility and instability in aqueous media...
January 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/28250345/design-and-synthesis-of-pyridazine-containing-compounds-with-promising-anticancer-activity
#6
Salwa Elmeligie, Eman Mohamed Ahmed, Suzan Mohamed Abuel-Maaty, Sawsan Abo-Bakr Zaitone, Demiana Samir Mikhail
Certain pyridazine containing compounds 2a-f, 3a, b, 4a, b, 5a, b, 6a and b were synthesized and characterized by spectroscopic means and elemental analysis. All the synthesized compounds were screened for their cytotoxic activity in vitro on colon cancer cell line (HCT-116) and breast cancer cell line (MCF-7). In addition, the antitumor activity of the synthesized compounds was tested in vivo against Ehrlich's ascites carcinoma (EAC) solid tumor grown in mice. The in vitro vascular endothelial growth factor receptor (VEGFR) enzyme inhibition assay was carried out for the most active compounds at a single dose of 10 µM...
2017: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28247937/estimation-of-interleukin-1%C3%AE-promoter-31%C3%A2-c-t-511-t-c-polymorphisms-and-its-level-in-coronary-artery-disease-patients
#7
Nasimudeen R Jabir, Chelapram K Firoz, Salwa Hindawi, Shazi Shakil, Ghazi A Damanhouri, Syed Kashif Zaidi, Shams Tabrez
Interleukin-1β (IL-1β) is an inflammation-causing cytokine that exerts several unique biological effects and could lead to future adverse events of CAD. The piece of work presented herein is aimed at investigating possible association of levels of IL-1β to its polymorphic site viz. -511 and -31 at promoter region in Saudi CAD patients. The study included 155 confirmed CAD patients and 80 healthy control individuals both men and women. Concentration of IL-1β in the patients' serum was measured by ELISA method...
March 1, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28236193/optimization-of-cellulase-production-by-halobacillus-sp-qls-31-isolated-from-lake-qarun-egypt
#8
Ahmed H Korany, Amal E Ali, Tamer M Essam, Salwa A Megahed
A halophilic cellulase-producing bacterium was isolated from a sediment sample collected from Lake Qarun (Fayoum Province, Egypt). Molecular identification based on 16S rDNA amplification and sequencing revealed 99% homology with Halobacillus sp. and hence was designated as Halobacillus sp. QLS 31. Medium composition and culture conditions were optimized for enhancing the production of cellulase enzyme using the Plackett-Burman statistical design. Ten variables were evaluated for their influence on cellulase production...
February 24, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28183196/the-application-of-current-proposed-venous-thromboembolism-risk-assessment-model-for-ambulatory-patients-with-cancer
#9
Hikmat Abdel-Razeq, Asem Mansour, Salwa S Saadeh, Mahmoud Abu-Nasser, Mohammad Makoseh, Murad Salam, Alaa Abufara, Yousef Ismael, Alaa Ibrahim, Ghaleb Khirfan, Mohammad Ibrahim
Venous thromboembolism (VTE) is a commonly encountered problem in patients with cancer. In recent years, cancer treatment paradigm has shifted with most therapy offered in ambulatory outpatient settings. Excess of half VTEs in patients with cancer occur in outpatient settings without prior hospitalization, where current practice guidelines do not recommend routine prophylaxis. Risk assessment models (RAMs) for VTE in such patients were recently introduced. This study aims to assess the practical application of one of these models in clinical practice...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/28152478/cytotoxic-effect-of-ferrimagnetic-glass-ceramic-nanocomposites-on-bone-osteosarcoma-cells
#10
Amira M Gamal-Eldeen, Salwa A M Abdel-Hameed, Sherien M El-Daly, Mona A M Abo-Zeid, Menha M Swellam
This work pointed out the anti-cancer effect of ferrimagnetic glass ceramic nanocomposites (CaO-ZnO-Fe2O3-SiO2), which contain high amount of magnetite (∼60%), crystallite size <100nm, and different nucleating agents on bone cancer Saos-2 cells. The cell viability was inhibited by FH and FW to <50% and <25%, respectively, with/without magnetism, and both also reduced mitochondrial transmembrane potential (ΔYm), with/without magnetism (no influence of magnetism). Histone deacetylase (HDAC) activity was inhibited by FH, FW, and FHPNT, with/without magnetism...
April 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28151567/first-molecular-epidemiology-of-entamoeba-histolytica-e-dispar-and-e-moshkovskii-infections-in-yemen-different-species-specific-associated-risk-factors
#11
Mona A Al-Areeqi, Hany Sady, Hesham M Al-Mekhlafi, Tengku Shahrul Anuar, Abdulelah H Al-Adhroey, Wahib M Atroosh, Salwa Dawaki, Fatin Nur Elyana, Nabil A Nasr, Init Ithoi, Yee-Ling Lau, Johari Surin
OBJECTIVES: To investigate the molecular epidemiology of Entamoeba histolytica, E. dispar and E. moshkovskii infections among rural communities in Yemen. METHODS: In a community-based study, faecal samples were collected from 605 participants and examined by wet mount, formalin-ether sedimentation, trichrome staining and nested multiplex PCR techniques. Demographic, socio-economic and environmental information was collected using a pre-tested questionnaire. RESULTS: Overall, 324 (53...
February 2, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28150327/new-3-substituted-2-4-hydroxyanilino-pyridine-derivatives-synthesis-antitumor-activity-and-tubulin-polymerization-inhibition
#12
Salwa Elmeligie, Nadia A Khalil, Eman M Ahmed, Soha H Emam
A series of new pyridine derivatives 4a-c, 5a-d, 6a-d, 7a-f, and 8a-f structurally related to ABT-751 were synthesized and characterized by spectroscopic means and elemental analysis. All the synthesized compounds were tested for their cytotoxic activity in vitro against the HCT-116 and HepG-2 cancer cell lines using the MTT assay. The results showed that compound 8d has higher cytotoxic activity than the reference antimitotic agent colchicine, against both tested cell lines, with IC50  = 0.52 and 1.40 μM, respectively...
February 2, 2017: Archiv der Pharmazie
https://www.readbyqxmd.com/read/28135324/predictors-of-medication-adherence-and-blood-pressure-control-among-saudi-hypertensive-patients-attending-primary-care-clinics-a-cross-sectional-study
#13
Sarah M Khayyat, Salwa M Saeed Khayyat, Raghda S Hyat Alhazmi, Mahmoud M A Mohamed, Muhammad Abdul Hadi
PURPOSE: To assess the level of medication adherence and to investigate predictors of medication adherence and blood pressure control among hypertensive patients attending primary healthcare clinics in Makkah, Saudi Arabia. PATIENTS AND METHODS: Hypertensive patients meeting the eligibility criteria were recruited from eight primary care clinics between January and May 2016 for this study. The patients completed Arabic version of Morisky Medication Adherence Scale (MMAS-8), an eight-item validated, self-reported measure to assess medication adherence...
2017: PloS One
https://www.readbyqxmd.com/read/28118396/correction-spliceosome-snrnp200-promotes-viral-rna-sensing-and-irf3-activation-of-antiviral-response
#14
Nicolas Tremblay, Martin Baril, Laurent Chatel-Chaix, Salwa Es-Saad, Alex Young Park, Robert K Koenekoop, Daniel Lamarre
[This corrects the article DOI: 10.1371/journal.ppat.1005772.].
January 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28090491/allelic-variance-among-abo-blood-group-genotypes-in-a-population-from-the-western-region-of-saudi-arabia
#15
Abdularahman B O Mohamed, Salwa Ibrahim Hindawi, Sameer Al-Harthi, Qamre Alam, Mohammad Zubair Alam, Absarul Haque, Waseem Ahmad, Ghazi A Damanhouri
BACKGROUND: Characterization of the ABO blood group at the phenotype and genotype levels is clinically essential for transfusion, forensics, and population studies. This study elucidated ABO phenotypes and genotypes, and performed an evaluation of their distribution in individuals from the western region of Saudi Arabia. METHODS: One-hundred and seven samples underwent standard serological techniques for ABO blood group phenotype analysis. ABO alleles and genotypes were identified using multiplex polymerase chain reaction, and electrophoretic analysis was performed to evaluate the highly polymorphic ABO locus...
December 2016: Blood Research
https://www.readbyqxmd.com/read/28073903/assessing-patient-safety-culture-in-tunisian-operating-rooms-a-multicenter-study
#16
Manel Mallouli, Mohamed Ayoub Tlili, Wiem Aouicha, Mohamed Ben Rejeb, Chekib Zedini, Amrani Salwa, Ali Mtiraoui, Mohamed Ben Dhiab, Thouraya Ajmi
OBJECTIVE: To assess the patient safety culture (PSC) in operating rooms (ORs) and to determine influencing factors. DESIGN: A cross-sectional descriptive multicenter study which was conducted over a period of 7 months (October 2014-April 2015) using the French validated version of the Hospital Survey On Patient Safety Culture questionnaire. SETTING: Of the note, 15 ORs of public and private healthcare institutions. PARTICIPANTS: In total, there were 368 participants including surgeons, anesthesiologists, surgical and anesthesia technicians, nurses and caregivers, divided into 316 professionals exercising in public sector and 52 working in private one...
January 9, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28061857/coordinated-regulation-of-acid-resistance-in-escherichia-coli
#17
Patricia Aquino, Brent Honda, Suma Jaini, Anna Lyubetskaya, Krutika Hosur, Joanna G Chiu, Iriny Ekladious, Dongjian Hu, Lin Jin, Marianna K Sayeg, Arion I Stettner, Julia Wang, Brandon G Wong, Winnie S Wong, Stephen L Alexander, Cong Ba, Seth I Bensussen, David B Bernstein, Dana Braff, Susie Cha, Daniel I Cheng, Jang Hwan Cho, Kenny Chou, James Chuang, Daniel E Gastler, Daniel J Grasso, John S Greifenberger, Chen Guo, Anna K Hawes, Divya V Israni, Saloni R Jain, Jessica Kim, Junyu Lei, Hao Li, David Li, Qian Li, Christopher P Mancuso, Ning Mao, Salwa F Masud, Cari L Meisel, Jing Mi, Christine S Nykyforchyn, Minhee Park, Hannah M Peterson, Alfred K Ramirez, Daniel S Reynolds, Nae Gyune Rim, Jared C Saffie, Hang Su, Wendell R Su, Yaqing Su, Meng Sun, Meghan M Thommes, Tao Tu, Nitinun Varongchayakul, Tyler E Wagner, Benjamin H Weinberg, Rouhui Yang, Anastasia Yaroslavsky, Christine Yoon, Yanyu Zhao, Alicia J Zollinger, Anne M Stringer, John W Foster, Joseph Wade, Sahadaven Raman, Natasha Broude, Wilson W Wong, James E Galagan
BACKGROUND: Enteric Escherichia coli survives the highly acidic environment of the stomach through multiple acid resistance (AR) mechanisms. The most effective system, AR2, decarboxylates externally-derived glutamate to remove cytoplasmic protons and excrete GABA. The first described system, AR1, does not require an external amino acid. Its mechanism has not been determined. The regulation of the multiple AR systems and their coordination with broader cellular metabolism has not been fully explored...
January 6, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/28039211/long-term-follow-up-of-patients-with-paroxysmal-atrial-fibrillation-and-severe-left-atrial-scarring-comparison-between-pulmonary-vein-antrum-isolation-only-or-pulmonary-vein-isolation-combined-with-either-scar-homogenization-or-trigger-ablation
#18
Sanghamitra Mohanty, Prasant Mohanty, Luigi Di Biase, Chintan Trivedi, Eli Hamilton Morris, Carola Gianni, Pasquale Santangeli, Rong Bai, Javier E Sanchez, Patrick Hranitzky, G Joseph Gallinghouse, Amin Al-Ahmad, Rodney P Horton, Richard Hongo, Salwa Beheiry, Claude S Elayi, Dhanunjaya Lakkireddy, Yaruva Madhu Reddy, Juan F Viles Gonzalez, J David Burkhardt, Andrea Natale
AIMS: Left atrial (LA) scarring, a consequence of cardiac fibrosis is a powerful predictor of procedure-outcome in atrial fibrillation (AF) patients undergoing catheter ablation. We sought to compare the long-term outcome in patients with paroxysmal AF (PAF) and severe LA scarring identified by 3D mapping, undergoing pulmonary vein isolation (PVAI) only or PVAI and the entire scar areas (scar homogenization) or PVAI+ ablation of the non-PV triggers. METHODS AND RESULTS: Totally, 177 consecutive patients with PAF and severe LA scarring were included...
December 29, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28028396/the-hidden-function-of-vitamin-d
#19
Hiba Sibaii, Salwa Refat El-Zayat, Azza Abd El-Shaheed, Nermine N Mahfouz, Sara F Sallam, Marwa H El Azma
AIM: There are no reports regarding the influence of vitamin D on thymosin ß4 and the cluster of differentiation CD4 levels which are important for maintaining a healthy immune system. Consequently, we aimed to explore this relationship through a study. MATERIAL AND METHODS: The study was carried out on 35 subjects, screened for 25-hydroxy vitamin D[25 (OH) D] using ELISA method and they were divided into two groups: Group 1 consists of 10 healthy subjects with sufficient vit...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28024620/chitosan-banana-peel-powder-nanocomposites-for-wound-dressing-application-preparation-and-characterization
#20
Nagwa A Kamel, Salwa L Abd El-Messieh, Neveen M Saleh
Wound infection is a serious infection has been spread worldwide. In order to provide fast aid treatments for such infection, banana peels have been incorporated within chitosan as wound dressing. Banana was collected from Egyptian markets peeled and the dried peels were grounded to powder, Incorporated as nano fillers within chitosan matrix with different concentrations (0, 2, 5 and 10wt%). Glycerol was added as plasticizer and crosslinker to the membranes. The banana peel powder (BPP) particle shape and size were determined using Transmission Electron Microscope (TEM), The homogeneity and distribution of BPP in the membranes were investigated through Scanning Electron Microscope (SEM)...
March 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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