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fibrin glue fistule

Kenneth M Keogh, Neil J Smart
Fistula in ano is a very common presentation to colorectal clinic. Embarrassment due to the symptoms makes accurate estimations of incidence difficult. It is estimated that up to 40% of peri-anal abscess will be accompanied by or preceded by a fistula. Fistulae can be classified into simple fistulae that involve no or minimal sphincter muscle and complex, which involve significant amounts of the anal sphincter muscle, possibly with multiple tracts. For complex fistulae a seton suture is usually placed through the tract and out through the anus to form a loop allowing pockets of sepsis to drain internally and externally and a mature tract of fibrous tissue to develop...
January 2016: Medical Hypotheses
Xiuwen Wu, Jianan Ren, Gefei Wang, Guosheng Gu, Xiaoting Li, Huajian Ren, Zhiwu Hong, Jieshou Li
GOALS: This study was designed to investigate the risk factors affecting glue-assisted closure (GAC) in the enterocutaneous fistula (ECF) patients receiving glue application. BACKGROUND: ECF is a challenging problem in surgical practice, and it is difficult to resolve by spontaneous closure. Currently, GAC is popular when treating fistulas, but data related to risk factors are limited. METHODS: We retrospectively analyzed 82 patients with 93 ECFs, who had autologous glue sealing from 2010 to 2012 in a referral center...
April 2015: Journal of Clinical Gastroenterology
Tetsuji Soda, Hiroshi Kiuchi, Yoichi Kakuta, Yasutomo Nakai, Tsunekazu Mizushima, Akira Tsujimura, Norio Nonomura
A 56- year-old man underwent a laparoscopic low anterior resection for rectal cancer (cT3bN0M0). Postoperatively, he was fairly well and started oral intake on postoperative day (POD) 9. On POD 14, he had an uncomfortable feeling during urination and noticed pneumaturia, and urinalysis revealed hematopyuria. Abdominal computed tomography (CT) showed air collection in the left seminal vesicle and bladder, and colonoscopy demonstrated a fistula at the anastomotic site. Abdominal CT following the fistulography under colonoscopy demonstrated fistulous communication between the rectum and left seminal vesicle...
December 2013: Hinyokika Kiyo. Acta Urologica Japonica
M Radionov, D D Ziya, I Sechanov
It is done an analysis of 191 patients operated on for crypto-glandular chronic fistulous paraproctitis. The age of the patients vary 21 to 76 years and the male:female proportion is 2,25 to 1. In 164 patients it was first operation for fistula-in-ano and in 27 cases it was a consecutive one for reccurence. There was intervened a concomitant other disease of the anal channel which pathogenetically predispose the development of fistula in 54 (28%) cases. The patients were discharged 1-3 days after surgery. Ambulant control and ligature procedures up to the 30th day were done...
2013: Khirurgiia
Jan Voswinkel, Sabine Francois, Norbert-Claude Gorin, Alain Chapel
Mesenchymal stromal cells (MSC) are multipotent adult stem cells with the potential to regenerate tissue damage and inhibit inflammation and fibrosis in parallel. As they are non-immunogenic, MSC can be safely auto- and allotransplanted and consequently represent a therapeutic option for refractory connective tissue diseases and fistulizing colitis like Crohn's disease. Actually, there are more than 200 registered clinical trial sites for evaluating MSC therapy, 22 are on autoimmune diseases and 27 are actually recruiting bowel disease' patients...
July 2013: Immunologic Research
Pravin J Gupta, Shalini N Gupta, P S Heda
Anorectal fistulas are common maladies. The challenge in therapy of perianal fistulas balances between the best possible cure and the preservation of continence. Complex fistulous disease challenges even the most experienced surgical specialists. The management options in these groups of patients are inadequate, with treatment often requiring multiple procedures, causing a risk for continued symptoms and fecal incontinence. This has lead to a serious search for newer and safer treatment options. Use of different types of setons and advancement flaps have their own advantages and pitfalls...
2012: Acta Chirurgica Iugoslavica
Luis A Borda Mederos, Luis I Chiroque Benites, Jesús O Pinto Elera, Ana J Manzaneda Pineda
Treatment of complex anal fistula is a surgical challenge because the risk of sphincter injury with the possibility of developing fecal incontinence. There are many techniques for the treatment of anal fistulas such as fistulotomy, fistulectomy, seton, endorectal advancement flap and fibrin glue, with different rates of recurrence and fecal incontinence. The biologic plug Surgisis® AFP it's being used since 2006 and produces the closure of the fistula in approximately 12 weeks, without surgery, by replacement of the fistulous tract by cells of the patient, apparently having advantages over other techniques...
October 2011: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
Helena Tabry, Paul A Farrands
Anal fistulae are common and debilitating; they are characterized by severe pain and discharge. They arise following infection near the anal canal, or as a primary event from an abscess in the abdomen, fistulating into the vagina or perianal skin. The term 'cryptoglandular' is given to abscesses arising from the anal glands.For many years, the treatment of choice was to lay open the fistula; however, this risks causing incontinence with potentially devastating consequences. Alternative surgical treatments include setons, fibrin glue, collagen plugs and flaps to cover the internal fistula opening...
December 2011: Canadian Journal of Gastroenterology, Journal Canadien de Gastroenterologie
Sherief Shawki, Steven D Wexner
Fistula-in-ano is the most common form of perineal sepsis. Typically, a fistula includes an internal opening, a track, and an external opening. The external opening might acutely appear following infection and/or an abscess, or more insiduously in a chronic manner. Management includes control of infection, assessment of the fistulous track in relation to the anal sphincter muscle, and finally, definitive treatment of the fistula. Fistulotomy was the most commonly used mode of management, but concerns about post-fistulotomy incontinence prompted the use of sphincter preserving techniques such as advancement flaps, fibrin glue, collagen fistula plug, ligation of the intersphincteric fistula track, and stem cells...
July 28, 2011: World Journal of Gastroenterology: WJG
Eric J Moore, Kerry D Olsen, Eliot J Martin
OBJECTIVES: 1) Determine the incidence of pharyngocutaneous fistula associated with transoral robotic oropharyngectomy with concurrent neck dissection. 2) Discuss prevention and treatment of pharyngocutaneous fistulization as a consequence of transoral oropharyngeal surgery with concurrent neck dissection. METHODS: Retrospective, single-institution chart review of 148 consecutive patients who underwent transoral robotic surgery with synchronous neck dissection for oropharyngeal neoplasia April 2007 to February 2010...
March 2011: Laryngoscope
V de Parades, J-D Zeitoun, P Atienza
Fistula arising from the glands of the anal crypts is the most common form of anoperineal sepsis. It is characterized by a primary internal orifice in the anal canal, a fistulous tract, and an abscess and/or secondary perineal orifice with purulent discharge. Antibiotics are not curative. The treatment of an abscess is urgent and consists, whenever possible, of incision and drainage under local anesthesia. Definitive treatment of the fistulous tract can await a second stage. The primary aim is to control infection without sacrificing anal continence...
August 2010: Journal of Visceral Surgery
Jorge Avalos-González, Eliseo Portilla-deBuen, Caridad Aurea Leal-Cortés, Abel Orozco-Mosqueda, María del Carmen Estrada-Aguilar, Gabriela Abigail Velázquez-Ramírez, Gabriela Ambriz-González, Clotilde Fuentes-Orozco, Aldo Emmerson Guzmán-Gurrola, Alejandro González-Ojeda
AIM: To assess whether the use of fibrin sealant shortens the closure time of postoperative enterocutaneous fistulas (ECFs). METHODS: The prospective case-control study included 70 patients with postoperative ECFs with an output of < 500 mL/d, a fistulous tract of > 2 cm and without any local complication. They were divided into study (n = 23) and control groups (n = 47). Esophageal, gastric and colocutaneous fistulas were monitored under endoscopic visualization, which also allowed fibrin glue application directly through the external hole...
June 14, 2010: World Journal of Gastroenterology: WJG
Stefan D Holubar, Bruce G Wolff
In the last 5 years, significant advances have been made in the surgical approaches to, and medical management of, Crohn's disease (CD). This review summarizes these advances as they relate to the care of surgical patients with CD, with an emphasis on innovations in surgical techniques, specifically minimally invasive (laparoscopic) surgery, as well as on recent developments in biologic pharmacotherapies for CD that have important clinical implications for surgical patients. These include recent insights gained into the role of biologic therapy with infliximab and other newer agents in preoperative and postoperative therapy of CD patients...
July 2009: Expert Review of Clinical Immunology
Rishabh Sehgal, Walter A Koltun
No abstract text is available yet for this article.
June 2010: Gastroenterology
Damian Garcia-Olmo, Dolores Herreros, Isabel Pascual, José Antonio Pascual, Emilio Del-Valle, Jaime Zorrilla, Paloma De-La-Quintana, Mariano Garcia-Arranz, Maria Pascual
PURPOSE: The feasibility and safety of stem cell-based therapy with expanded adipose-derived stem cells (ASCs) has been investigated in a phase I clinical trial. The present study was designed as a phase II multicenter, randomized controlled trial to further investigate the effectiveness and safety of ASCs in the treatment of complex perianal fistulas. METHODS: Patients with complex perianal fistulas (cryptoglandular origin, n = 35; associated with Crohn's disease, n = 14) were randomly assigned to intralesional treatment with fibrin glue or fibrin glue plus 20 million ASCs...
January 2009: Diseases of the Colon and Rectum
M Alan, Z Yener, I Tasal, B Bakir
The aims of this study were to investigate whether fibrin glue can be used to close experimentally induced incisions of the teat (mammary papillae) in lactating goats and to compare the healing of the glued with the sutured incisions. Four clinically healthy lactating dairy goats, namely 8 mammary papillae were used. After surgical preparation of the papillae, a 3.5 cm long incision of each papilla was made through skin, muscular layer and mucosa into the papillary sinus. The wounds in the right papillae in all goats were closed with U-shaped uninterrupted 00 chromic catgut sutures...
May 2008: DTW. Deutsche Tierärztliche Wochenschrift
Chad A Eicher, Anthony B Adelson, Jeffrey A Himmelberg, Udaya Chintalapudi
A persistent biliary-cutaneous fistula detected after biliary drainage catheter removal could not be resolved with diversionary techniques and Gelfoam and fibrin glue administration in the fistulous tract. As an alternative approach for treatment of the fistula, obliteration of the contributing bile duct with laser ablation was performed.
February 2008: Journal of Vascular and Interventional Radiology: JVIR
E A Alibai, A K Rahmanian, A Razmkon, S A Nabavizadeh
The occurrence of tension pneumocephalus following intracranial aneurysm surgery is a rare event. Here, we present a case of extradural tension pneumocephalus following pterional craniotomy for the treatment of intracavernous internal carotid artery aneurysm. It has been caused by a fistulous communication between the posterior wall of the frontal sinus and the extradural space. Successful obliteration of this aberrant communication tract was performed using fibrin glue, with complete resolution of the pneumocephalus...
November 2008: Emergency Radiology
D Fuks, O Bréhant, F Dumont, L Viart, D Manaouil, E Bartoli, T Yzet, F Mauvais, J M Regimbeau
BACKGROUND: Cutaneous fistulas from the rectal stump after Hartmann procedure are not rare. Rarely do they require operative intervention, but they may result in prolonged skin care during hospitalization. PURPOSE: of study: To describe the use of fibrin glue in the treatment of rectocutaneous fistulas occurring after Hartmann procedure. STUDY DESIGN: Ten patients underwent irrigation of the fistulous tract followed by fibrin glue injection...
January 2007: Journal de Chirurgie
Enrique Casal, Alberto de San Ildefonso, Juan Sánchez, Cristina Facal, José Pampin
Anal fistula is a frequent condition. The most commonly accepted origin is infectious. The most widely used classification is based on cryptoglandular theory and on the position of the fistulous tract in relation to the anal sphincter. Physical examination will help to identify the type of fistula and allow its treatment to be planned. The most widely used complementary tests are endoanal ultrasound and magnetic resonance imaging. We review the various therapeutic options and their results, especially fistulotomy, endorectal advancement flap, use of sedal, anodermal advancement flap, sphincterorrhaphy with sphincter repair, and fibrin glue...
December 2005: Cirugía Española
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