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https://www.readbyqxmd.com/read/28527367/ysicochemical-properties-lipid-oxidation-and-sensory-attributes-of-pork-patties-with-lupin-protein-concentrate-stored-in-vacuum-modified-atmosphere-and-frozen-state
#1
Marzena Danowska-Oziewicz, Lidia Kurp
The effect of lupin protein concentrate (LPC) addition on selected physicochemical properties, lipid oxidation and sensory quality of pork patties was investigated. LPC was added at the level 1%, 2% and 3%. Patties were packed in vacuum and modified atmosphere (MA) and stored 42days in a refrigerator while aerobically packed patties were stored 84days in a frozen state. Patties with LPC showed a lower cooking loss, were less cohesive and juicy, and demonstrated a non-typical flavour compared to the control samples...
May 10, 2017: Meat Science
https://www.readbyqxmd.com/read/28525801/social-and-built-environment-factors-related-to-children-s-independent-mobility-the-importance-of-neighbourhood-cohesion-and-connectedness
#2
En-Yi Lin, Karen Witten, Melody Smith, Penelope Carroll, Lanuola Asiasiga, Hannah Badland, Karl Parker
This study examines aspects of neighbourhood social environments (namely, neighbourhood safety, cohesion and connection) and child-specific built environment attributes in relation to children's independent mobility. The results suggest that children aged 8-13 years with parents who perceive their neighbourhood as more cohesive and more connected, and are located closer to school, engaged in higher levels of independently mobile trips. The qualitative component of this research revealed that for NZ European, Māori, Samoan and other Pacific parents, 'people danger' was the most common concern for letting their children go out alone, whereas for Asian and Indian parents, 'traffic danger' was the most common reason for their concern...
May 16, 2017: Health & Place
https://www.readbyqxmd.com/read/28525648/the-role-of-omics-in-the-application-of-adverse-outcome-pathways-for-chemical-risk-assessment
#3
Erica K Brockmeier, Geoff Hodges, Thomas H Hutchinson, Emma Butler, Markus Hecker, Knut Erik Tollefsen, Natalia Garcia-Reyero, Peter Kille, Dörthe Becker, Kevin Chipman, John Colbourne, Timothy W Collette, Andrew Cossins, Mark Cronin, Peter Graystock, Steve Gutsell, Dries Knapen, Ioanna Katsiadaki, Anke Lange, Stuart Marshall, Stewart F Owen, Edward J Perkins, Stewart Plaistow, Anthony Schroeder, Daisy Taylor, Mark Viant, Gerald Ankley, Francesco Falciani
In conjunction with the second International Environmental Omics Symposium (iEOS) conference, held at the University of Liverpool (UK) in September 2014, a workshop was held to bring together experts in toxicology and regulatory science from academia, government and industry. The purpose of the workshop was to review the specific roles that high-content omics datasets (e.g., transcriptomics, metabolomics, lipidomics, and proteomics) can hold within the adverse outcome pathway (AOP) framework for supporting ecological and human health risk assessments...
May 19, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28522983/a-dynamical-model-of-pitch-memory-provides-an-improved-basis-for-implied-harmony-estimation
#4
Ji Chul Kim
Tonal melody can imply vertical harmony through a sequence of tones. Current methods for automatic chord estimation commonly use chroma-based features extracted from audio signals. However, the implied harmony of unaccompanied melodies can be difficult to estimate on the basis of chroma content in the presence of frequent nonchord tones. Here we present a novel approach to automatic chord estimation based on the human perception of pitch sequences. We use cohesion and inhibition between pitches in auditory short-term memory to differentiate chord tones and nonchord tones in tonal melodies...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28521644/slope-stability-and-bearing-capacity-of-landfills-and-simple-on-site-test-methods
#5
Atsushi Yamawaki, Yoichi Doi, Kiyoshi Omine
This study discusses strength characteristics (slope stability, bearing capacity, etc.) of waste landfills through on-site tests that were carried out at 29 locations in 19 sites in Japan and three other countries, and proposes simple methods to test and assess the mechanical strength of landfills on site. Also, the possibility of using a landfill site was investigated by a full-scale eccentric loading test. As a result of this, landfills containing more than about 10 cm long plastics or other fibrous materials were found to be resilient and hard to yield...
May 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/28516917/maternal-age-dependent-apc-c-mediated-decrease-in-securin-causes-premature-sister-chromatid-separation-in-meiosis-ii
#6
Ibtissem Nabti, Rosanna Grimes, Hema Sarna, Petros Marangos, John Carroll
Sister chromatid attachment during meiosis II (MII) is maintained by securin-mediated inhibition of separase. In maternal ageing, oocytes show increased inter-sister kinetochore distance and premature sister chromatid separation (PSCS), suggesting aberrant separase activity. Here, we find that MII oocytes from aged mice have less securin than oocytes from young mice and that this reduction is mediated by increased destruction by the anaphase promoting complex/cyclosome (APC/C) during meiosis I (MI) exit. Inhibition of the spindle assembly checkpoint (SAC) kinase, Mps1, during MI exit in young oocytes replicates this phenotype...
May 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28516822/key-drivers-of-patient-experience-in-ambulatory-paediatric-cardiology
#7
Shalini D Allam, Mary Mehta, Bertha Ben Khallouq, James F Burrows, Paul Rosen
Patient experience is becoming a central focus of healthcare. A broad range of studies on how to increase patient satisfaction ratings exists; however, they lack the specificity to adequately guide physicians and hospitals on how to improve patient experience. The objective of this study was to define the aspects of patient experience within paediatric cardiologist practices that can serve as predictors of excellent patient satisfaction. From 1 January, 2013 to 28 February, 2015 (26 months), outpatients who visited paediatric cardiologists were asked to complete a 39-question patient satisfaction survey regarding their experience...
May 18, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28514186/apc-c-cdc20-mediates-deprotection-of-centromeric-cohesin-at-meiosis-ii-in-yeast
#8
Katarzyna Jonak, Ievgeniia Zagoriy, Tugce Oz, Peter Graf, Julie Rojas, Valentina Mengoli, Wolfgang Zachariae
Cells undergoing meiosis produce haploid gametes through one round of DNA replication followed by two rounds of chromosome segregation. This requires that cohesin complexes, which establish sister chromatid cohesion during S phase, are removed in a stepwise manner. At meiosis I, the separase protease triggers the segregation of homologous chromosomes by cleaving cohesin's Rec8 subunit on chromosome arms. Cohesin persists at centromeres because the PP2A phosphatase, recruited by the shugoshin protein, dephosphorylates Rec8 and thereby protects it from cleavage...
May 17, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28512441/mapping-the-paths-from-styles-of-anger-experience-and-expression-to-obsessive-compulsive-symptoms-the-moderating-roles-of-family-cohesion-and-adaptability
#9
Liang Liu, Cuilian Liu, Xudong Zhao
Previous research has shown strong connections of anger experience and expression with obsessive-compulsive (OC) symptoms. Additionally, studies have demonstrated links between family environment variables and obsessive-compulsive disorder (OCD). Our study aims to integrate the perspectives from these two literatures by exploring the moderating roles of family cohesion and family adaptability in the relationship between anger proneness and suppression and OCD symptoms. A total of 2008 college students were recruited from a comprehensive university in Shanghai, China between February and May 2016...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28508069/high-predation-habitats-affect-the-social-dynamics-of-collective-exploration-in-a-shoaling-fish
#10
Christos C Ioannou, Indar W Ramnarine, Colin J Torney
Collective decisions play a major role in the benefits that animals gain from living in groups. Although the mechanisms of how groups collectively make decisions have been extensively researched, the response of within-group dynamics to ecological conditions is virtually unknown, despite adaptation to the environment being a cornerstone in biology. We investigate how within-group interactions during exploration of a novel environment are shaped by predation, a major influence on the behavior of prey species...
May 2017: Science Advances
https://www.readbyqxmd.com/read/28506890/biomechanics-of-the-transport-barrier-in-the-nuclear-pore-complex
#11
REVIEW
George J Stanley, Ariberto Fassati, Bart W Hoogenboom
The nuclear pore complex (NPC) is the selective gateway through which all molecules must pass when entering or exiting the nucleus. It is a cog in the gene expression pathway, an entrance to the nucleus exploited by viruses, and a highly-tuned nanoscale filter. The NPC is a large proteinaceous assembly with a central lumen occluded by natively disordered proteins, known as FG-nucleoporins (or FG-nups). These FG-nups, along with a family of soluble proteins known as nuclear transport receptors (NTRs), form the selective transport barrier...
May 12, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28505850/damage-cluster-distributions-in-numerical-concrete-at-the-mesoscale
#12
Okan Yılmaz, Peter Michael Derlet, Jean-François Molinari
We investigate the size distribution of damage clusters in concrete under uniaxial tension loading conditions. Using the finite-element method, the concrete is modeled at the mesoscale by a random distribution of elastic spherical aggregates within an elastic mortar paste. The propagation and coalescence of damage zones are then simulated by means of dynamically inserted cohesive elements. Dynamic failure analysis shows that the size distribution of damage clusters follows a power law when a system-spanning cluster is first observed, with an exponent close to that of percolation theory...
April 2017: Physical Review. E
https://www.readbyqxmd.com/read/28505849/compaction-of-noncohesive-and-cohesive-granular-materials-under-vibrations-experiments-and-stochastic-model
#13
J-E Mathonnet, P Sornay, M Nicolas, B Dalloz-Dubrujeaud
We study the time evolution of the compaction of a noncohesive or cohesive granular material submitted to shaking through experiments and a stochastic model. Beyond well-known empirical expressions, we show that the characteristic time scales depend on the number of objects in the assembly. For a noncohesive granular material, the compaction time scale is governed by the number of individual grains in the system. In the case of a cohesive granular material, a two-scale model (individual particles and clusters) allows one to mimic the time evolution of the compaction of an actual cohesive powder driven by horizontal vibrations...
April 2017: Physical Review. E
https://www.readbyqxmd.com/read/28505718/mechanics-of-a-granular-skin
#14
Somnath Karmakar, Anit Sane, S Bhattacharya, Shankar Ghosh
Magic sand, a hydrophobic toy granular material, is widely used in popular science instructions because of its nonintuitive mechanical properties. A detailed study of the failure of an underwater column of magic sand shows that these properties can be traced to a single phenomenon: the system self-generates a cohesive skin that encapsulates the material inside. The skin, consisting of pinned air-water-grain interfaces, shows multiscale mechanical properties: they range from contact-line dynamics in the intragrain roughness scale, to plastic flow at the grain scale, all the way to sample-scale mechanical responses...
April 2017: Physical Review. E
https://www.readbyqxmd.com/read/28503215/fast-determination-of-structurally-cohesive-subgroups-in-large-networks
#15
Robert S Sinkovits, James Moody, B Tolga Oztan, Douglas R White
Structurally cohesive subgroups are a powerful and mathematically rigorous way to characterize network robustness. Their strength lies in the ability to detect strong connections among vertices that not only have no neighbors in common, but that may be distantly separated in the graph. Unfortunately, identifying cohesive subgroups is a computationally intensive problem, which has limited empirical assessments of cohesion to relatively small graphs of at most a few thousand vertices. We describe here an approach that exploits the properties of cliques, k-cores and vertex separators to iteratively reduce the complexity of the graph to the point where standard algorithms can be used to complete the analysis...
November 2016: Journal of Computational Science
https://www.readbyqxmd.com/read/28502659/apc-c-cdh1-enables-removal-of-shugoshin-2-from-the-arms-of-bivalent-chromosomes-by-moderating-cyclin-dependent-kinase-activity
#16
Ahmed Rattani, Randy Ballesteros Mejia, Katherine Roberts, Maurici B Roig, Jonathan Godwin, Michael Hopkins, Manuel Eguren, Luis Sanchez-Pulido, Elwy Okaz, Sugako Ogushi, Magda Wolna, Jean Metson, Alberto M Pendás, Marcos Malumbres, Béla Novák, Mary Herbert, Kim Nasmyth
In mammalian females, germ cells remain arrested as primordial follicles. Resumption of meiosis is heralded by germinal vesicle breakdown, condensation of chromosomes, and their eventual alignment on metaphase plates. At the first meiotic division, anaphase-promoting complex/cyclosome associated with Cdc20 (APC/C(Cdc20)) activates separase and thereby destroys cohesion along chromosome arms. Because cohesion around centromeres is protected by shugoshin-2, sister chromatids remain attached through centromeric/pericentromeric cohesin...
May 10, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28501814/a-scoping-review-protocol-on-social-participation-of-indigenous-elders-intergenerational-solidarity-and-their-influence-on-individual-and-community-wellness
#17
Chantal Viscogliosi, Hugo Asselin, Suzy Basile, Yves Couturier, Marie-Josée Drolet, Dominique Gagnon, Jill Torrie, Mélanie Levasseur
INTRODUCTION: Indigenous elders have traditionally played an important role in maintaining social cohesion within their communities. Today, part of this role has been taken over by government social and healthcare services, but they are having limited success in addressing social challenges. Increasing elders' social participation and intergenerational solidarity might foster community development and benefit young people, families, communities and the elders themselves. However, knowledge of the contribution of elders' social participation and intergenerational solidarity to wellness is scattered and needs to be synthesised...
May 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28499338/hyaluronic-acid-molecular-weight-dependent-modulation-of-mucin-nanostructure-for-potential-mucosal-therapeutic-applications
#18
Irene Maria Hansen, Morten Frendø Ebbesen, Liselotte Kaspersen, Troels Thomsen, Konrad Bienk, Yunpeng Cai, Birgitte Mølholm Malle, Kenneth Alan Howard
This study investigates the effects of different molecular weight hyaluronic acid (HA) on the mucosal nanostructure using a pig stomach mucin hydrogel as a mucosal barrier model. Micro- (1.0 µm) and nanoparticles (200 nm) were used as probes and their movement in mucin was studied by a 3D confocal microscopy-based particle tracking technique and by nanoparticle tracking analysis (NTA) after addition of high (900 kDa) and low (33 kDa) molecular weight HA. This demonstrated a molecular weight-dependent HA modulation of the mucin nanostructure with a 2...
May 12, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28497540/meikin-associated-polo-like-kinase-specifies-bub1-distribution-in-meiosis-i
#19
Seira Miyazaki, Jihye Kim, Yuya Yamagishi, Tadashi Ishiguro, Yuki Okada, Yuji Tanno, Takeshi Sakuno, Yoshinori Watanabe
In meiosis I, sister chromatids are captured by microtubules emanating from the same pole (mono-orientation), and centromeric cohesion is protected throughout anaphase. Shugoshin, which is localized to centromeres depending on the phosphorylation of histone H2A by Bub1 kinase, plays a central role in protecting meiotic cohesin Rec8 from separase cleavage. Another key meiotic kinetochore factor, meikin, may regulate cohesion protection, although the underlying molecular mechanisms remain elusive. Here, we show that fission yeast Moa1 (meikin), which associates stably with CENP-C during meiosis I, recruits Plo1 (polo-like kinase) to the kinetochores and phosphorylates Spc7 (KNL1) to accumulate Bub1...
May 12, 2017: Genes to Cells: Devoted to Molecular & Cellular Mechanisms
https://www.readbyqxmd.com/read/28492646/high-pressure-micromechanical-force-measurements-of-the-effects-of-surface-corrosion-and-salinity-on-ch4-c2h6-hydrate-particle-surface-interactions
#20
Shenglong Wang, Sijia Hu, Erika P Brown, Matthew A Nakatsuka, Jiafei Zhao, Mingjun Yang, Yongchen Song, Carolyn A Koh
In order to investigate the mechanism of gas hydrate deposition and agglomeration in gas dominated flowlines, a high-pressure micromechanical force (MMF) apparatus was applied to directly measure CH4/C2H6 hydrate adhesion/cohesion forces under low temperature and high pressure conditions. A CH4/C2H6 gas mixture was used as the hydrate former. Adhesion forces between hydrate particles and carbon steel (CS) surfaces were measured, and the effects of corrosion on adhesion forces were analyzed. The influences of NaCl concentration on the cohesion force between CH4/C2H6 hydrate particles were also studied for gas-dominated systems...
May 11, 2017: Physical Chemistry Chemical Physics: PCCP
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